CN217568831U - Auxiliary device for stereotactic microinjection - Google Patents
Auxiliary device for stereotactic microinjection Download PDFInfo
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- CN217568831U CN217568831U CN202120846811.9U CN202120846811U CN217568831U CN 217568831 U CN217568831 U CN 217568831U CN 202120846811 U CN202120846811 U CN 202120846811U CN 217568831 U CN217568831 U CN 217568831U
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Abstract
The utility model discloses an auxiliary device for stereotactic microinjection, which comprises a base, a first supporting column and a second supporting column, wherein the first supporting column is arranged on the upper end surface of the base, the first supporting column is vertical to the base, and the first supporting column is fixedly connected with the base; the second supporting column is vertical to the first supporting column, and the second supporting column is fixedly connected with the upper end of the first supporting column; the second support column comprises a fixing frame for fixing the centrifugal tube. The utility model has small integral volume, occupies smaller area while playing the role of fixing a centrifuge tube, and can be matched with the existing stereotaxic instrument for use; and the centrifugal tube can be positioned at a proper position by adjusting the first supporting column and the second supporting column according to the positioning requirement.
Description
Technical Field
The utility model belongs to the technical field of biological assay apparatus, concretely relates to is an auxiliary device for stereotactic microinjection.
Background
In the operation of injecting virus or medicine into the brain of an animal in a micro-scale manner, a micro-injector is utilized to suck a micro-amount of recombinant virus or medicine reagent into the tip of a glass electrode, and then the micro-amount of recombinant virus or medicine reagent is injected into the brain of the animal. Because the absorbed dose is very small, usually 1-5 mul, in order to accurately, slowly and stably absorb the reagent, the micro syringe is usually required to be fixed on a stereotaxic instrument, because the tip of the glass electrode is thin and soft, the glass electrode is easy to be broken by touching the wall of the centrifugal tube in the process of slowly and manually entering the glass electrode fixed on the micro syringe pump into a 0.2/0.5/1.5/2/10ml centrifugal tube for containing the reagent, and if the glass electrode is broken carelessly, the needle needs to be manufactured again, thus the experimental efficiency is very influenced.
Therefore, the experimental operation has higher requirements on the stability of fixing the virus or the medicine container, and the position for sucking the recombinant medicine or the virus every time is not fixed, so that the position of the recombinant medicine or the virus is flexibly adjusted along with the placement of the micro syringe. Because stereotaxic apparatus structure is complicated, the space that can place the centrifuge tube rack is limited, and present centrifuge tube rack is firm, but the volume is great usually, and the great centrifuge tube rack of volume can't be placed and use on stereotaxic apparatus.
SUMMERY OF THE UTILITY MODEL
In order to solve the technical problem, the utility model provides an auxiliary device for stereotactic microinjection, it is small, can place and use on stereotaxic instrument, the effectual problem that exists among the prior art of having solved.
An auxiliary device for stereotactic microinjection comprises a base, a first supporting column and a second supporting column, wherein the first supporting column is arranged on the upper end surface of the base, is vertical to the base and is fixedly connected with the base; the second supporting column is vertical to the first supporting column, and the second supporting column is fixedly connected with the upper end of the first supporting column; the second support column comprises a fixing frame for fixing the centrifugal tube.
Further, the base is a solid metal base.
Or the base is made of solid metal or plastic.
Further, the bottom of the base includes an absorbent structure.
Furthermore, the first support column is a first telescopic rod capable of adjusting the longitudinal height.
Furthermore, the first telescopic rod comprises a first sleeve and a first sleeve rod, the bottom of the first sleeve is fixedly connected with the base, and the first sleeve rod is sleeved inside the first sleeve; the first sleeve comprises a first limiting piece, and the first limiting piece limits the position of the first sleeve rod relative to the first sleeve.
Furthermore, the first limiting part comprises a first threaded cylinder and a first limiting handle, the first threaded cylinder is connected with the sleeve in an integrated mode, the first limiting handle comprises an external thread, and the first limiting handle is in threaded connection with the first threaded cylinder.
Further, the second support column is a second telescopic rod capable of adjusting the transverse length.
Further, the second telescopic rod comprises a second sleeve and a second loop bar, and the second loop bar is sleeved inside the second sleeve; one end of the sleeve II is fixedly connected with the upper end of the sleeve rod I; the second sleeve comprises a second limiting part which limits the position of the second sleeve rod.
Or the telescopic rod II comprises a sleeve II and a sleeve rod II, and the sleeve rod II is sleeved in the sleeve II; one end of the sleeve II is rotatably connected with the upper end of the sleeve rod I; the second sleeve comprises a second limiting part which limits the position of the second sleeve rod.
Furthermore, a threaded hole is formed in the upper end face of the sleeve rod II and penetrates through the sleeve rod II; and screws are arranged in the threaded holes.
Further, locating part two includes a screw thread section of thick bamboo two and spacing handle two, and a screw thread section of thick bamboo two and two body coupling of sleeve, and spacing handle two includes the external screw thread, and spacing handle two and two threaded connection of a screw thread section of thick bamboo.
Further, the mount is including the retainer plate that is used for fixed centrifuging tube, and the retainer plate includes the link plate of a body coupling, and the retainer plate passes through link plate and loop bar two combination coupling.
Further, the hanging plate is an L-shaped hanging plate; the loop bar II comprises a through hole allowing the hanging plate to pass through, and the length of the L-shaped hanging plate is larger than that of the through hole.
Further, the retainer plate is circular circle, and the internal diameter of retainer plate is greater than the pipe diameter of centrifuging tube and is less than the external diameter of the lid of centrifuging tube.
Or the fixing frame is a fixing ring, and the fixing ring is connected with the loop bar in a whole.
Or the second supporting column comprises a fixed plate and a sliding plate, and the sliding plate is connected with the fixed plate in a sliding manner; one end of the fixing plate is fixedly or rotatably connected with the upper end of the first loop bar.
Furthermore, the fixing frames with different specifications are arranged, so that the centrifugal tube fixing device is suitable for centrifugal tubes with different specifications.
The utility model has the advantages that the auxiliary device for stereotactic microinjection has small overall volume, occupies smaller area while playing the role of fixing a centrifuge tube, and can be matched with the existing stereotaxic instrument for use; and the centrifugal tube can be positioned at a proper position by adjusting the first supporting column and the second supporting column according to the positioning requirement.
Drawings
Fig. 1 is a schematic front view of embodiment 1 of the present invention;
fig. 2 is a schematic view of the overall structure of embodiment 1 of the present invention;
FIG. 3 is a schematic structural view of the centrifuge tube not placed in the embodiment 1 of the present invention;
fig. 4 is a schematic front view of embodiment 2 of the present invention;
fig. 5 is a schematic view of the overall structure of embodiment 2 of the present invention;
fig. 6 is a schematic view of a partially separated and enlarged structure of a fixing frame and a loop bar ii according to embodiment 2 of the present invention;
fig. 7 is a schematic front view of embodiment 3 of the present invention;
fig. 8 is a schematic view of the overall structure of embodiment 3 of the present invention;
FIG. 9 is an enlarged schematic view of the connection between the connection plate and the loop bar;
fig. 10 is a schematic structural view in front view of li 4 according to an embodiment of the present invention;
fig. 11 is a schematic view of the overall structure of embodiment 4 of the present invention;
fig. 12 is a schematic view of the separation structure of the fixing plate, the sliding plate and the fixing frame of the present invention;
in the figure, 1, a base; 11. a suction cup; 21. a first sleeve; 22. a loop bar I; 23. a first thread cylinder; 24. a first limiting handle; 31. a second sleeve; 311. a connecting plate; 312. a "T" shaped screw; 32. a loop bar II; 33. a second threaded cylinder; 34. a second limiting handle; 4. a fixed ring; 41. hanging the plate; 42. a through hole; 5. centrifuging the tube; 61. a fixing plate; 62. a sliding plate; 63. a slider; 64. a chute.
Detailed Description
The technical solutions in the embodiments of the present invention will be described in detail below with reference to specific embodiments, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, rather than all embodiments, and those skilled in the art can easily understand other advantages and effects of the present invention from the disclosure in the specification. The utility model discloses can also implement or use through other different concrete implementation modes, under the circumstances of conflict-free, the characteristics in following embodiment and the embodiment can the intercombination, based on the embodiment of the utility model provides a, all other embodiments that ordinary skilled person in the art obtained under the prerequisite of not making creative work all belong to the scope of the utility model protection.
Example 1
As shown in fig. 1 to 3, a centrifuge tube 5 support in this embodiment includes a base 1, a first support column and a second support column, the first support column is disposed on an upper end surface of the base 1, the first support column is perpendicular to the base 1, and the first support column is fixedly connected to the base 1; the second supporting column is vertical to the first supporting column, and the second supporting column is fixedly connected with the upper end of the first supporting column; the second support column comprises a fixing frame for fixing the centrifuge tube 5.
In this embodiment, the base 1 is a solid metal base 1, and the weight of the base 1 is greater than 100 g.
The first support column is a first telescopic rod with adjustable longitudinal height; the first telescopic rod comprises a first sleeve 21 and a first sleeve rod 22, the bottom of the first sleeve 21 is fixedly connected with the base 1, and the first sleeve rod 22 is sleeved inside the first sleeve 21; the first sleeve 21 comprises a first limiting part, and the first limiting part limits the position of the first sleeve rod 22 relative to the first sleeve 21; the sleeve I21 is a cylindrical barrel, the sleeve rod I22 is a cylindrical rod, and the sleeve rod I22 can slide upwards or downwards; the first limiting part comprises a first threaded barrel 23 and a first limiting handle 24, the first threaded barrel 23 is integrally connected with the first sleeve 21, the first limiting handle 24 comprises external threads, and the first limiting handle 24 is in threaded connection with the first threaded barrel 23.
The second supporting column is a telescopic rod II capable of adjusting the transverse length; the second telescopic rod comprises a second sleeve 31 and a second sleeve rod 32, and the second sleeve rod 32 is sleeved inside the second sleeve 31; one end of the sleeve II 31 is fixedly connected with the upper end of the sleeve rod I22; the second sleeve 31 comprises a second limiting part, and the second limiting part limits the position of the second sleeve rod 32; a threaded hole is formed in the upper end face of the second sleeve rod 32 and penetrates through the second sleeve 31; a screw is arranged in the threaded hole; the sleeve II 31 is a cylindrical barrel, the sleeve rod II 32 is a cylindrical rod, and the sleeve rod II 32 can slide transversely; the second limiting part comprises a second threaded barrel 33 and a second limiting handle 34, the second threaded barrel 33 is integrally connected with the second sleeve 31, the second limiting handle 34 comprises external threads, and the second limiting handle 34 is in threaded connection with the second threaded barrel 33.
The fixing frame is a fixing ring 4, and the fixing ring 4 is integrally connected with the second loop bar 32.
When the auxiliary device for stereotactic microinjection is used, a gap is formed between the first loop bar 22 and the first sleeve 21 by rotating the first limit handle 24, and the first loop bar 22 slides upwards or downwards, so that the height of the upper end surface of the first loop bar 22 is adjusted, or the position of the first loop bar 22 is fixed; the centrifugal tube 5 is inserted into the fixing ring 4 from the top down, thereby fixing the position of the centrifugal tube 5.
Example 2
As shown in fig. 4 to 6, the present embodiment is different from embodiment 1 in that: the mount includes the retainer plate 4 that is used for fixed centrifuging tube 5, and retainer plate 4 includes integral connection's link plate 41, and retainer plate 4 passes through link plate 41 and two 32 built-up connections of loop bar.
The hanging plate 41 is an L-shaped hanging plate 41; the loop bar II 32 comprises a through hole 42 allowing the hanging plate 41 to pass through, and the length of the L-shaped hanging plate 41 is greater than that of the through hole 42; retainer plate 4 is circular circle, and the internal diameter of retainer plate 4 is greater than centrifuge tube 5's pipe diameter and is less than the external diameter of centrifuge tube 5's lid. When in use, the hanging plate 41 is hung in the through hole 42 of the loop bar II 32.
The base 1 is made of solid metal or plastic, and the bottom of the base 1 comprises an adsorption structure; the adsorption structure is a sucker 11, and the sucker 11 is fixedly connected with the base 1.
Example 3
As shown in fig. 7 to 9, the present embodiment is different from embodiment 1 in that: the second telescopic rod comprises a second sleeve 31 and a second sleeve rod 32, and the second sleeve rod 32 is sleeved inside the second sleeve 31; one end of the sleeve II 31 is rotatably connected with the upper end of the sleeve rod I22; the second sleeve 31 comprises a second limiting piece, and the second limiting piece limits the position of the second sleeve rod 32.
The connecting plate 311 is arranged at one end of the second sleeve 31, the connecting plate 311 is integrally connected with the second sleeve 31, the connecting plate 311 is fixedly connected with the upper end of the first sleeve rod 22 through the T-shaped screw 312, when the connecting device is used, the T-shaped screw 312 is screwed down to enable the connecting plate 311 to be firmly connected with the first sleeve rod 22, and the connecting plate 311 can be rotated after the T-shaped screw 312 is screwed out, so that the direction of the second sleeve 31 can be adjusted.
Example 4
As shown in fig. 10 to 12, the present embodiment is different from embodiment 2 in that: the second telescopic rod comprises a second sleeve 31 and a second sleeve rod 32, and the second sleeve rod 32 is sleeved inside the second sleeve 31; one end of the sleeve II 31 is rotatably connected with the upper end of the sleeve rod I22; the second sleeve 31 comprises a second limiting piece, and the second limiting piece limits the position of the second sleeve rod 32.
The second support column comprises a fixed plate 61 and a sliding plate 62, and the sliding plate 62 is connected with the fixed plate 61 in a sliding manner; one end of the fixed plate 61 is rotatably connected with the upper end of the loop bar I22; the sliding plate 62 comprises a sliding block 63, the fixed plate 61 comprises a sliding slot 64 matched with the sliding block 63, and the sliding plate 62 can slide relative to the fixed plate 61; the slider 63 includes a washer that acts as a stop for the slider 63.
The above description of the embodiments is only intended to illustrate the present invention. It should be noted that, for those skilled in the art, without departing from the principle of the present invention, several modifications can be made to the present invention, and these modifications will also fall within the scope of the claims of the present invention.
Claims (10)
1. An auxiliary device for stereotactic microinjection comprises a base, a first supporting column and a second supporting column, and is characterized in that the first supporting column is arranged on the upper end surface of the base, is vertical to the base and is fixedly connected with the base; the second supporting column is vertical to the first supporting column, and the second supporting column is fixedly connected with the upper end of the first supporting column; the second support column comprises a fixing frame for fixing the centrifuge tube.
2. An aid for stereotactic microinjection as claimed in claim 1, wherein said base is a solid metal base.
3. The aid device for stereotactic microinjection as claimed in claim 1, wherein said bottom of said base comprises an absorbent structure.
4. An aid for stereotactic microinjection as claimed in claim 3, wherein said first support post is a first telescoping rod whose longitudinal height can be adjusted.
5. The auxiliary device for stereotactic microinjection as claimed in claim 4, wherein said first telescoping shaft comprises a first sleeve and a first sleeve rod, the bottom of the first sleeve is fixedly connected to the base, and the first sleeve rod is sleeved inside the first sleeve; the first sleeve comprises a first limiting piece, and the first limiting piece limits the position of the first sleeve rod relative to the first sleeve.
6. The auxiliary device of claim 5, wherein the second supporting post is a second telescopic rod capable of adjusting a transverse length, the second telescopic rod comprises a second sleeve and a second sleeve, and the second sleeve is sleeved inside the second sleeve; one end of the sleeve II is fixedly connected with the upper end of the sleeve rod I; the second sleeve comprises a second limiting part which limits the position of the second sleeve rod.
7. The auxiliary device of claim 5, wherein the second supporting post is a second telescopic rod capable of adjusting a transverse length, the second telescopic rod comprises a second sleeve and a second sleeve, and the second sleeve is sleeved inside the second sleeve; one end of the sleeve II is rotatably connected with the upper end of the sleeve rod I; the second sleeve comprises a second limiting part which limits the position of the second sleeve rod.
8. The assisting apparatus for stereotactic microinjection of claim 7, wherein said fixing frame comprises a fixing ring for fixing a centrifuge tube, said fixing ring comprises an integrally connected hanging plate, and said fixing ring is connected to a loop bar by a combination of said hanging plate and said loop bar.
9. The aid device according to claim 5, wherein the second support column comprises a fixed plate and a sliding plate, the sliding plate being slidably connected to the fixed plate; one end of the fixing plate is fixedly or rotatably connected with the upper end of the loop bar I.
10. The auxiliary device for stereotactic microinjection of claim 9, wherein said sliding plate comprises a sliding block, the fixed plate comprises a sliding slot matching with the sliding block, the sliding plate is slidable with respect to the fixed plate; the slider includes the packing ring, and the packing ring plays spacing effect to the slider.
Priority Applications (1)
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CN202120846811.9U CN217568831U (en) | 2021-04-23 | 2021-04-23 | Auxiliary device for stereotactic microinjection |
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CN202120846811.9U CN217568831U (en) | 2021-04-23 | 2021-04-23 | Auxiliary device for stereotactic microinjection |
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CN217568831U true CN217568831U (en) | 2022-10-14 |
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CN202120846811.9U Active CN217568831U (en) | 2021-04-23 | 2021-04-23 | Auxiliary device for stereotactic microinjection |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116327416A (en) * | 2023-05-22 | 2023-06-27 | 中国人民解放军军事科学院军事医学研究院 | Ball base positioning instrument |
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2021
- 2021-04-23 CN CN202120846811.9U patent/CN217568831U/en active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116327416A (en) * | 2023-05-22 | 2023-06-27 | 中国人民解放军军事科学院军事医学研究院 | Ball base positioning instrument |
CN116327416B (en) * | 2023-05-22 | 2023-08-25 | 中国人民解放军军事科学院军事医学研究院 | Ball base positioning instrument |
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