CN217543122U

CN217543122U - Sample collecting bottle

Info

Publication number: CN217543122U
Application number: CN202122465679.XU
Authority: CN
Inventors: 蔡政君; 商涛; 唐林勇; 孔健希
Original assignee: Hangzhou Lin'an Aikang Biotechnology Co ltd
Current assignee: Hangzhou Lin'an Aikang Biotechnology Co ltd
Priority date: 2021-09-29
Filing date: 2021-10-13
Publication date: 2022-10-04
Anticipated expiration: 2031-10-13

Abstract

The utility model provides a sample collecting bottle, which comprises a bottle body with an opening at one end, wherein the bottle body is divided into an upper bottle body and a lower bottle body, and the upper bottle body is adjacent to the opening; the upper bottle body and the lower bottle body are connected through a boss; the boss is provided with a groove communicated with the lower bottle body. In biological sample inspection procedure, sample collecting bottle and sampling stick cooperation can fully collect the sample in the sampling stick to accomplish the preceding processing step of the schizolysis of sample in step, improve the utilization ratio of sampling sample.

Description

Sample collecting bottle

Technical Field

The utility model belongs to the technical field of medical instrument, especially, relate to a sample receiving flask that is used for collecting liquid sample with the cooperation of sampling stick.

Background

There are a variety of clinical Lateral Flow ("Lateral Flow" or "LF") immunoassay devices that can be used to detect the presence of analytes in a sample, such as hormones, sugars, adulterants, drugs of abuse, neocoronavirus, and the like. Typically, after a fluid sample is collected and added to a lateral flow immunoassay device, the amount of analyte in the fluid sample is measured.

Wherein the fluid sample may be any volume of fluid that is tested, examined, or studied. The fluid sample may be derived from any fluid, for example a bodily fluid such as saliva or blood or urine or other fluid to be tested such as a water sample from a source of contamination, a fluid sample from a beverage, etc.

Liquid samples are typically collected and absorbed using a sampling wand having a collection element formed of an absorbent material such as a pad or sponge attached to one end of a plunger. The collection element allows a sufficient volume of sample fluid to be absorbed from the fluid source, the presence of sample fluid in the collection element causing the interior of the collection element to expand. The collection element typically retains the sample until the collection element is manipulated to release the sample. During detection, a fluid sample needs to be extruded out of a collecting element of a sampling rod and then added to a lateral flow immunoassay device; in some assays, the fluid sample is mixed with the buffer solution before the sample is added to the buffer solution, or the fluid sample is squeezed out of the collection element of the sample wand and added to the buffer solution.

Taking the detection of the new coronavirus as an example to illustrate the existing operation, a collecting bottle with a lysate of the new coronavirus prestored inside is used for collecting a fluid sample on a collecting element, namely, the end of the collecting element of a sampling rod is inserted into the collecting bottle, and the collecting element is contacted with the side wall or the bottom of the collecting bottle body to extrude the collecting element so that the fluid sample flows out of the collecting bottle for sample collection. The prior art has the problems that the fluid sample on the collecting element can not be fully released (more fluid sample remains on the collecting element and can not be used for detection), or when buffer solution exists in the collecting bottle, the collecting element can absorb and take away part of the buffer solution or the mixed solution of the buffer solution and the fluid sample, so that the subsequent detection liquid is insufficient in quantity, and the detection result is inaccurate (for example false negative) and even the detection is failed due to insufficient sample.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a sample receiving flask for collecting liquid sample to the not enough that exists among the prior art.

For this reason, the above-mentioned purpose of the present invention is achieved by the following technical solutions:

a sample collection vial, wherein the sample collection vial comprises a vial body having an open end, the vial body being divided into an upper vial body and a lower vial body, wherein the upper vial body is adjacent to the open end; the upper bottle body is connected with the lower bottle body through a boss; the boss is provided with a groove communicated with the lower bottle body.

When adopting above-mentioned technical scheme, the utility model discloses can also adopt or make up and adopt following technical scheme:

as the utility model discloses a preferred technical scheme: the outer contour of the groove protrudes out of the outer surface of the lower bottle body.

As the utility model discloses a preferred technical scheme: the groove is of a chute-shaped structure, one end of the groove is positioned on the upper surface of the boss, and the other end of the groove is positioned on the side wall of the lower bottle body.

As the utility model discloses a preferred technical scheme: the grooves are four to six and are uniformly distributed on the lug boss and the side wall of the lower bottle body.

As the utility model discloses an preferred technical scheme: the boss is a hollow annular boss.

As the utility model discloses a preferred technical scheme: the upper bottle body and the lower bottle body are cylindrical or the upper bottle body and the lower bottle body are in a circular truncated cone shape.

As the utility model discloses a preferred technical scheme: the side wall of the upper bottle body is provided with a strip-shaped bulge.

As the utility model discloses a preferred technical scheme: a sealing membrane sealing the opening of the sample collection vial is also included.

Advantageous effects

The utility model discloses a boss and sampling rod's collection component contact makes collection component fully extruded, and the liquid sample among the collection component flows into down in the bottle through the recess. Both reached the effect of fully collecting the sample, still avoided simultaneously collecting the component and the condition that the buffer solution in the lower bottle contacted leads to the buffer solution to be taken away, realized the abundant collection of liquid sample and had abundant miscella and be used for next step's detection.

Drawings

Fig. 1 is a schematic view of a sample collection bottle provided by the present invention.

Fig. 2 is a top view of the sample collection bottle provided by the present invention.

Fig. 3 isbase:Sub>A schematic sectional view taken along linebase:Sub>A-base:Sub>A in fig. 2.

Fig. 4 is a schematic diagram of the cooperation of the sample collection bottle and the sampling rod provided by the present invention.

Fig. 5 is a cross-sectional view of the sample collection bottle and the sample rod provided by the present invention.

Reference numerals

Sample collection bottle 100, bottle body 10, upper bottle body 1, lower bottle body 2, opening 11, strip-shaped protrusion 12, boss 4, groove 3, groove end 31, groove other end 32, sampling rod 20, plunger 21 and collection element 22

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.

The above-described embodiments are intended to illustrate the present invention, is only a preferred embodiment of the invention, not a limitation of the invention, any modification, equivalent replacement, improvement, etc. made to the present invention within the spirit of the present invention and the scope of the claims fall within the scope of the present invention.

As shown in fig. 1-5, the present invention provides a sample collection bottle 100 having a bottle body 10, wherein an opening 11 is formed at one end of the bottle body 10, and the opening 11 can be sealed by a sealing film (not shown) when a buffer solution is pre-filled in the sample collection bottle. In use, after the sealing membrane is punctured, the sampling wand is inserted into the body 10 of the sample collection vial 100 through the opening 11. The bottle body 10 is divided into an upper body 1 and a lower body 2, wherein the upper body 1 is adjacent to the opening 11. The upper body 1 and the lower body 2 are cylindrical or the upper body 1 and the lower body 2 are truncated cone-shaped. As shown in fig. 1, the upper body 1 and the lower body 2 are each in a truncated cone shape. The sampling wand 20 includes a collecting member 21 and a plunger 22 connected to the collecting member. As shown in FIG. 2, the upper and

lower bodies

1, 2 are connected by a boss 4, the boss 4 being adapted to receive and contact a collection element 21 of a sampling wand 20 to facilitate the collection element 21 being squeezed. A groove 3 connected and communicated with the lower bottle body 2 is arranged on the boss 4, and the extruded fluid sample enters the lower bottle body 2 through the groove 3. In some embodiments, the boss 4 is a hollow annular boss to facilitate fluid flow, so that fluid can flow into the lower bottle body from the middle of the annular boss. When the collecting member 21 is pressed, the contact angle between the collecting member 21 and the annular boss and the sidewall of the upper body 1 can be adjusted to sufficiently press the collecting member 21.

As shown in fig. 1, 2 and 3, the groove 3 is in the shape of a chute, and the outer contour of the structure protrudes from the outer surface of the lower body, i.e. the contour of the groove is visible from the outside of the collection bottle. One end 31 of the groove is connected with the upper surface of the boss 4, and the other end 32 of the groove is connected with the inner side wall of the lower bottle body 2. That is to say, the initial section of the inclined groove-shaped groove 3 begins after the upper surface of the boss 4, part of the groove penetrates through the boss, part of the groove is positioned on the outer surface of the lower bottle body, and the final end of the groove penetrates through the side wall of the lower bottle body to be connected and communicated with the inner side wall. Thus, the groove 3 does not occupy the space of the lower body 2 and can effectively prevent the stagnation of the liquid. The grooves 3 are generally arranged in four to six and uniformly distributed on the boss 4 and the side wall of the lower bottle body 2.

In some embodiments, for convenience of operation, the sidewall of the upper bottle body 1 is provided with a strip-shaped protrusion 12.

Take the detection of new coronavirus as an example, the operation process of collecting and cracking the saliva sample by using the sample collecting bottle of the utility model is explained in detail. When the sampling device is used, as shown in fig. 4 and 5, a plunger of the sampling rod is held by a hand, the sampling rod with the saliva sample collected on the collecting element is placed above the opening 11 of the sample collecting bottle and then inserted into the sample collecting bottle, the collecting element is contacted with the boss, the sampling rod is continuously pressed downwards, the collecting element is extruded, the saliva sample flows out of the collecting element, flows into the lower bottle body along the hollow part (if arranged) of the groove or the annular boss, the extrusion force is continuously increased, the angle of the sampling rod in the collecting bottle is simultaneously adjusted, the extrusion is continuously carried out, and the sampling rod is pulled out until the collecting element is compressed to the maximum state and the liquid does not flow out any more. Mixing the saliva sample flowing into the sample collecting bottle with a lysis solution prestored in the sample collecting bottle, completing the lysis of the sample within a preset time, and then dropwise adding the mixed solution on new corona antigen detection test paper to complete the detection of the new corona antigen. The test paper can adopt lateral cross flow test paper of a double antibody sandwich method.

In biological sample inspection procedure, sample collecting bottle and sampling rod cooperation can fully collect the sample in the sampling rod, and can accomplish pretreatment steps such as the schizolysis of sample in step. The sampling rod can be used for improving the utilization rate of the sampling specimen in the detection items of allergens, tumor markers, gonadal markers, alpha-functional markers, infectious disease markers, diabetes markers, hepatic fibrosis markers and the like which need to be sampled by the sampling rod in the detection of the new coronavirus.

Claims

1. A sample collection bottle comprises a bottle body with an opening at one end, wherein the bottle body is divided into an upper bottle body and a lower bottle body, and the upper bottle body is adjacent to the opening; it is characterized in that the upper bottle body and the lower bottle body are connected through a boss; the boss is provided with a groove communicated with the lower bottle body.

2. The specimen collection vial of claim 1, wherein the recess has an outer contour that projects beyond an outer surface of the lower body.

3. The specimen collection vial of claim 2, wherein the groove is of a chute-shaped configuration, one end of the groove being located on the upper surface of the boss and the other end being located on the sidewall of the lower body.

4. The specimen collection bottle of claim 3, wherein the grooves are four to six and are evenly distributed at the boss and the sidewall of the lower body.

5. The specimen collection vial of any of claims 1-4, wherein the boss is a hollow annular boss.

6. The specimen collection vial of claim 1, wherein the upper body and the lower body are cylindrical or the upper body and the lower body are frustoconical.

7. The specimen collection vial of claim 1, wherein the sidewall of the upper body defines a raised strip.

8. The specimen collection vial of claim 1, further comprising a sealing membrane sealing the opening of the specimen collection vial.