CN217490945U

CN217490945U - Multifunctional detection test box

Info

Publication number: CN217490945U
Application number: CN202123223010.6U
Authority: CN
Inventors: 杨华卫; 成诚; 刘陈晨
Original assignee: Jiangsu Huntarray Biotechnology Co ltd
Current assignee: Jiangsu Huntarray Biotechnology Co ltd
Priority date: 2021-12-21
Filing date: 2021-12-21
Publication date: 2022-09-27
Anticipated expiration: 2031-12-21

Abstract

The utility model provides a many functional detection test case, include: a box portion; a pipette tip cartridge for loading pipette tips; a centrifuge tube rack for holding centrifuge tubes; and a PCR tube cassette for placing a PCR tube; the pipette tip box, the centrifuge tube rack and the PCR tube box are respectively formed inside the box body part, and the centrifuge tube rack and the PCR tube box are positioned at the same side of the pipette tip box.

Description

Multifunctional detection test box

Technical Field

The utility model relates to a detection experiment auxiliary equipment, concretely relates to multifunctional detection test case.

Background

In detection experiments such as biological, chemical and medical research, instruments such as pipette tips, centrifuge tubes and PCR tubes are commonly used to perform operations such as sampling and sample application. For example, pipette tip cartridges, centrifuge tube holders, and PCR tube cartridges are commonly used in gene amplification diagnostics, and are also used in conventional rapid sample nucleic acid extraction. However, pipette tip cartridges, centrifuge rack and PCR tube cartridges are used at different sites, each instrument being independent. Therefore, it is inconvenient to carry and easy to miss when in use. To detecting, experimental operation in same place, through using solitary pipettor tip head box, centrifuge tube rack and PCR pipe box respectively, not only influence operating efficiency, a large amount of samples are easy chaotic when using moreover, can cause mutual pollution even, and go out to carry inconveniently, use extremely inconveniently. In addition, a plurality of pipettors tip head box, centrifuge tube rack and PCR pipe box are placed alone and are taken up space great in the detection experiment process, also can influence the detection experiment operation.

SUMMERY OF THE UTILITY MODEL

To the technical problem as above, the utility model aims at providing a multi-functional test box, it can load the pipettor suction head simultaneously and place centrifuging tube and PCR pipe, when going out the detection service, uses this multi-functional test box can effectively save space, and convenient to use, is favorable to improving and detects experimental efficiency.

Therefore, according to the utility model provides a multi-functional detection test case, include: a box portion; a pipette tip cartridge for loading pipette tips; a centrifuge tube rack for placing centrifuge tubes; and a PCR tube cassette for placing a PCR tube; the pipette tip box, the centrifuge tube rack and the PCR tube box are respectively formed inside the box body part, and the centrifuge tube rack and the PCR tube box are positioned at the same side of the pipette tip box.

In one embodiment, a first partition and a second partition are provided inside the case portion, perpendicular to the bottom of the case portion, and the first partition is perpendicular to the second partition, thereby partitioning the pipette tip cartridge, the centrifuge tube rack, and the PCR tube cartridge.

In one embodiment, the heights of the pipette tip cartridge, the PCR, and the centrifuge tube rack cartridge are configured to decrease progressively.

In one embodiment, a plurality of first placement holes are provided in the pipette tip magazine, which are distributed uniformly, for the loading of pipette tips.

In one embodiment, the distance between the axial centers of the adjacent first placing holes is set to be in the range of 8.6-23.3 mm.

In one embodiment, the pipette tip cartridge further comprises a cartridge cover provided at an upper end opening thereof.

In one embodiment, a plurality of second placing holes are uniformly distributed in the centrifuge tube rack and used for placing centrifuge tubes.

In one embodiment, the distance between the axial centers of the adjacent second placing holes is set to be in the range of 14-20 mm.

In one embodiment, a plurality of third placing holes are uniformly distributed in the PCR tube box and used for placing PCR tubes, the third placing holes are configured to be tapered blind holes, and the inner diameter of each tapered blind hole is gradually reduced from outside to inside.

In one embodiment, the axial extension depth of the third placement holes is set to be in the range of 7.7-20mm, and the interval between the axial centers of the adjacent third placement holes is set to be in the range of 9-16 mm.

Compared with the prior art, the utility model has the advantages of:

according to the utility model discloses a many function test proof box is through setting up pipettor suction head box, centrifuge tube rack and PCR pipe box integration for many function test proof box has possessed simultaneously and has loaded the pipettor suction head, placed the centrifuging tube, and place the multiple functions of PCR pipe, is showing and has saved the inner space, has improved convenient to carry nature and convenience in use greatly. When going out to detect service, multi-functional detection test case convenient to use carries article and is difficult to omit. This multifunctional detection test box easy operation is convenient, and is efficient, pipettor suction head box can keep the liquid-transfering suction head clean and tidy, can effectively avoid producing the pollution each other during the application of sample.

Drawings

The present invention will be described with reference to the accompanying drawings.

Fig. 1 schematically shows a top view structure of a multifunctional test chamber according to the present invention.

FIG. 2 schematically shows a front view of the multifunctional test chamber of FIG. 1.

Fig. 3 schematically shows the structure of a pipette tip cartridge in the multifunctional detection test kit shown in fig. 1.

FIG. 4 schematically shows the structure of the centrifuge tube rack in the multifunctional test kit of FIG. 1.

FIG. 5 schematically shows a top view of the PCR cartridge in the multi-functional assay kit of FIG. 1.

FIG. 6 schematically shows a side view structure of the PCR tube cassette shown in FIG. 5.

In the present application, all the figures are schematic and are only intended to illustrate the principles of the present invention and are not drawn to scale.

Detailed Description

Fig. 1 and 2 schematically show the structure of a multifunctional test chamber 100 according to the present invention. As shown in fig. 1 and 2, the multifunctional detection test chamber 100 includes a case portion 1, a pipette tip cassette 2 for loading pipette tips, a centrifuge tube rack 3 for placing centrifuge tubes, and a PCR tube cassette 4 for placing PCR tubes. Preferably, the case portion 1 may be configured in a rectangular parallelepiped structure, the pipette tip cartridge 2, the centrifuge tube rack 3, and the PCR tube cartridge 4 are respectively formed inside the case portion 1, and the centrifuge tube rack 3 and the PCR tube cartridge 4 are at the same side of the pipette tip cartridge 2.

In one embodiment, a first partition 11 and a second partition 12 are provided inside the case portion 1 to be perpendicular to the bottom of the case portion 1, and the first partition 11 is perpendicular to the second partition 12, thereby partitioning a space corresponding to the pipette tip cartridge 2, the centrifuge tube rack 3, and the PCR tube cartridge 4.

It is of course understood that the pipette tip cassette 2, the centrifuge rack 3, and the PCR tube cassette 4 may be integrally fixed to each other by fixing the centrifuge rack 3 and the PCR tube cassette 4 to the side of the pipette tip cassette 2, respectively.

The utility model discloses a multi-functional test box 100 is through setting up pipettor suction head box 2,

centrifuge tube rack

3 and 4 integration of PCR pipe box for multi-functional test box 100 has possessed the loading pipettor suction head simultaneously, has placed the centrifuging tube, and places the multiple functions of PCR pipe, and can show and save the inner space, has improved convenient to carry nature and use convenience greatly.

According to the utility model discloses, pipettor pipette tip box 2, PCR pipe box 4 and centrifuge tube rack 3 highly set to steadilyd decrease. This is advantageous for keeping the pipette tip clean and tidy. When using multi-functional test box 100, the position of centrifuge tube rack 3 is close to operating personnel one side, can prevent like this that liquid from dripping on PCR tube box 4 in order to avoid causing the pollution when the application of sample.

Fig. 3 schematically shows the structure of the pipette tip cartridge 2. As shown in fig. 3, a plurality of first placement holes 21 are provided in the pipette tip cassette 2, the first placement holes 21 being uniformly distributed, and the first placement holes 21 are used for loading pipette tips. The plurality of first placing holes 21 are arranged in evenly spaced distribution in both the lateral direction and the longitudinal direction. The first placement hole 21 is provided extending inward in a plane perpendicular to the top of the pipette tip cartridge 2, thereby forming a blind hole.

In the embodiment shown in fig. 3, the plurality of first placing holes 21 on the pipette tip cartridge 2 are arranged in 6 × 6, thereby forming 36 hole sites. The diameter of the first placement hole 21 may be set to different sizes as necessary so that the pipette tip cartridge 2 can be loaded with pipette tips of different specifications such as 10 μ L, 200 μ L, 1mL, and the like. Therefore, the multifunctional detection test box 100 can be suitable for pipette tips of various different specifications, and the application range of the multifunctional detection test box 100 is widened.

In the present embodiment, the interval between the axial centers of the first placing holes 21 adjacent in the lateral and longitudinal directions is set to be in the range of 8.6 to 23.3mm, preferably, to be 8.6 mm. This kind of setting up mode of first placing hole 21 not only can provide suitable operating space for the pipettor, and the pipettor operation of being convenient for is favorable to make full use of pipettor suction head box 2's space moreover to save holistic occupation space.

In one embodiment, which is not shown, the pipette tip magazine 2 may be configured to include a cubic inner cavity and a first placement plate disposed in the inner cavity, on which a plurality of evenly distributed through holes are disposed, whereby the through holes are formed as first placement holes 21. The pipette tip can be placed into the through hole. The first placing plate has certain thickness to guarantee that the pipette tip can be stably placed in the through hole. The first placing plates may be provided with a plurality of first placing holes 21, and the first placing holes may be distributed at intervals, and the through holes of the first placing plates correspond to one another.

Preferably, the first placement plate is configured to be detachably connectable to an inner wall of the pipette tip cartridge 1. Not only conveniently load the pipettor suction head like this, be convenient for moreover to clear up the inside of pipettor suction head box 2.

According to the utility model discloses, pipettor pipette tip box 2 is still including setting up in its upper end open-ended lid 5. As shown in fig. 3, a first connection portion 23 and a first catch 22 are provided at opposite sides of the pipette tip cartridge 2, respectively. Meanwhile, a second connection part 53 and a second latch 52 are respectively provided at opposite side parts of the box cover 5. The first connecting portion 23 forms a fitting connection with the second connecting portion 53. For example, the first connection portion 23 and the second connection portion 53 may be formed in a hinge-like structure or a hinge structure, thereby achieving connection between the cartridge cover 5 and the pipette tip cartridge 2. Thus, the box cover 5 is opened or closed by opening and closing. After the box cover 5 is closed, the box cover 5 can be locked by the first buckle 22 and the second buckle 52 in a matched clamping mode, so that the box cover 5 and the pipette tip box 2 are tightly connected, and the box cover 5 can be stably connected with the pipette tip box 2 after being closed.

The box cover is opened only when the pipettor needs to be sleeved with the pipette tips, so that the pipette tips in the pipette tip box 2 can be effectively protected, and the pipette tip box 2 is effectively prevented from being polluted.

Fig. 4 schematically shows the structure of the centrifuge tube rack 3. As shown in fig. 4, the centrifuge tube rack 3 is configured as a block-shaped body, and a plurality of second placing holes 31 are uniformly distributed on the block-shaped body, and the second placing holes 31 are used for placing centrifuge tubes. The plurality of second placing holes 31 are arranged in evenly spaced distribution in both the lateral direction and the longitudinal direction. The second placing hole 31 is provided extending inward in a plane perpendicular to the top of the centrifuge tube rack 3, thereby forming a blind hole.

In the embodiment shown in fig. 4, the plurality of second placing holes 31 in the centrifuge tube rack 3 are arranged 3 × 3, thereby forming 9 hole sites. The diameter of the second placement hole 31 may be set to different sizes as needed, so that the pipette tip cartridge 2 can place centrifuge tubes of different specifications such as 0.5mL, 1.5mL, 2mL, 4mL, and 5 mL. From this for many functional test case 100 can be applicable to the centrifuging tube of multiple different specifications, has improved many functional test case 100's application scope.

In the present embodiment, the interval between the axial centers of the second placing holes 31 adjacent in the lateral and longitudinal directions is set to be in the range of 14 to 20mm, preferably, 14 mm. This kind of setting mode of second placing hole 31 not only is convenient for place the centrifuging tube, is favorable to absorbing the sample in the centrifuging tube moreover.

Fig. 5 and 6 schematically show the structure of the PCR cartridge 4. As shown in FIGS. 5 and 6, the PCR tube cassette 4 is provided with a plurality of third placing holes 41 uniformly distributed, and the third placing holes 41 are used for placing the PCR tubes. The plurality of third placing holes 41 are arranged in evenly spaced distribution in both the lateral direction and the longitudinal direction. The third placing hole 41 is provided extending inward in a direction perpendicular to the top plane of the centrifuge tube rack 3, thereby forming a blind hole.

In the embodiment shown in FIG. 5, the plurality of third placing holes 41 on the PCR tube cassette 4 are arranged in a 3X 5 arrangement, thereby forming 15 hole sites. The diameter of the third placing hole 41 may be set to different sizes as necessary so that the PCR tube cassette 4 can place different sizes of PCR tubes, for example, 0.2 mL. Therefore, the multifunctional detection test box 100 can be suitable for PCR tubes of various specifications, and the application range of the multifunctional detection test box 100 is improved.

In the present embodiment, the axial extension depth of the third placing hole 41 is set to be in the range of 7.7-20 mm. Meanwhile, the interval between the axial centers of the third placing holes 41 adjacent in the lateral and longitudinal directions is set to be in the range of 9 to 16mm, preferably, to be 9 mm. This arrangement of the third placing hole 41 not only facilitates placing the PCR tube but also facilitates adding the sample to the PCR tube.

According to the present invention, as shown in fig. 6, the third placing hole 41 is configured as a tapered blind hole, and the inner diameter of the tapered blind hole decreases progressively from the outside to the inside. This kind of structure of hole 41 is placed to the third not only conveniently places the PCR pipe, can make the outer wall of PCR pipe closely laminate with the toper inner wall of hole 41 is placed to the third moreover, is favorable to keeping the PCR pipe stable.

According to the novel use, the box body part 1, the pipette tip box 2, the centrifuge tube rack 3 and the PCR tube box 4 of the multifunctional detection test box 100 are made of plastic or metal.

The use of the multifunctional detection test box 100 according to the present invention is described below by taking 10 μ L pipette tips, 1.5mL centrifuge tubes, and 0.2mL PCR tubes as examples. The user uses the multi-functional test chamber 100 in nucleic acid sample extraction and detection. 10 μ L pipette tips were loaded into the pipette tip cassette.

First, a sample is extracted. The extraction tube (i.e., 1.5mL centrifuge tube) was placed on a 1.5mL centrifuge tube rack, and then the lid of the pipette tip box was opened, and after a 10. mu.L pipette tip was mounted on the pipette, the lid was closed. Then, 10. mu.L of the sample was aspirated by a pipette tip using a pipette, and added to the extraction tube. The 10 microliter pipette tip is a disposable article and is discarded once used.

Thereafter, detection is performed. After the extraction is completed, the PCR tube containing the amplification reaction solution is taken out and placed in the third placing hole of the PCR tube cassette. Then, the lid of the pipette tip box is opened again, a 10 μ L pipette tip is mounted on the lid again by using a pipette, and then 2 μ L of sample is aspirated from the extraction tube by using the pipette tip and added to the well-placed PCR tube for subsequent operations.

According to the utility model discloses a multi-functional test box 100 is through setting up pipettor suction head box 2,

centrifuge tube rack

3 and 4 integration of PCR pipe box for multi-functional test box 100 has possessed simultaneously and has loaded the pipettor suction head, placed the centrifuging tube, and the multiple function of placing the PCR pipe, is showing and has saved the inner space, has improved convenient to carry nature and use convenience greatly. When going out for detection service, the multifunctional detection test box 100 is convenient to use and is not easy to omit articles. This multifunctional detection test case 100 easy operation is convenient, and is efficient, pipettor suction head box 2 can keep the clean and tidy of pipettor suction head, can effectively avoid producing the pollution each other during the application of sample.

In the description of the present invention, it is to be understood that the terms "first", "second" and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implying any number of technical features indicated. Thus, features defined as "first", "second", "third" may explicitly or implicitly include one or more of the features. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.

In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

Finally, it should be noted that the above description is only a preferred embodiment of the present invention, and should not be construed as limiting the present invention in any way. Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing examples, or that equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A multifunctional detection test box is characterized by comprising:

a box portion (1);

a pipette tip cassette (2) for loading pipette tips;

a centrifuge tube rack (3) for placing centrifuge tubes; and

a PCR tube cassette (4) for placing a PCR tube;

the pipette tip box, the centrifuge tube rack and the PCR tube box are respectively formed in the box body part, and the centrifuge tube rack and the PCR tube box are positioned at the same side of the pipette tip box,

the pipette tip box comprises a box body part and is characterized in that a first partition plate and a second partition plate which are perpendicular to the bottom of the box body part are arranged in the box body part, the first partition plate is perpendicular to the second partition plate, so that the pipette tip box, the centrifuge tube rack and the PCR tube box are formed in a separated mode, and the heights of the pipette tip box, the PCR tube box and the centrifuge tube rack are set to be gradually reduced.

2. The multifunctional test kit according to claim 1, wherein a plurality of first evenly distributed placement holes (21) are provided in the pipette tip cassette for loading pipette tips.

3. The multifunctional detection test chamber according to claim 2, wherein a distance between the axial centers of the adjacent first placing holes is set to be in a range of 8.6 to 23.3 mm.

4. The multifunctional detection test chamber according to claim 2, wherein the pipette tip cartridge further comprises a cartridge cover (5) provided at an upper end thereof with an opening.

5. The multifunctional detection test box according to claim 1, wherein a plurality of second placing holes (31) are uniformly distributed in the centrifuge tube rack and used for placing centrifuge tubes.

6. The multifunctional detection test chamber according to claim 5, wherein a distance between axes of the second placement holes adjacent to each other is set to be in a range of 14 to 20 mm.

7. The multifunctional detection test chamber according to claim 1, wherein a plurality of uniformly distributed third placing holes (41) are formed in the PCR tube box and used for placing PCR tubes, the third placing holes are formed into tapered blind holes, and the inner diameter of each tapered blind hole is gradually reduced from outside to inside.

8. The multifunctional detection test chamber according to claim 7, wherein the axial extension depth of the third placement holes is set to be in the range of 7.7 to 20mm, and the interval between the axial centers of the adjacent third placement holes is set to be in the range of 9 to 16 mm.