CN216473219U - Open kit and reagent detection device - Google Patents

Abstract

The application relates to an open kit and reagent detection device, the open kit of this application includes: the reagent box comprises an outer frame, a reagent tray, an outer support frame and a turnover cover, wherein the outer frame is provided with an accommodating space; the reagent tray is arranged in the accommodating space, and a plurality of first accommodating holes are formed in the top surface of the reagent tray; the outer support frame is connected with the outer frame and is arranged at intervals with the reagent tray, an outer mounting box is arranged on the outer support frame, and at least one second accommodating hole is formed in the top surface of the outer mounting box; the turning cover can be rotatably connected to the outer frame, and an opening position is arranged on the turning cover; therefore, the open type reagent kit can enable the first accommodating hole and the second accommodating hole to be kept in an open state when the flip cover covers through the open position arranged on the flip cover; when the reagent detection device is applied to the reagent detection device, the pollution among samples can be avoided, the working efficiency is high, the application range is wide, and the cost is reduced.

Description

Open kit and reagent detection device

Technical Field

The application relates to the field of gene detection, in particular to an open type kit and a reagent detection device.

Background

Gene detection has become a major research tool used in clinical molecular experiments. The precondition of gene detection is the extraction of biological sample nucleic acids of high quality and purity. Therefore, nucleic acid extraction and purification, gene library construction and PCR amplification become important steps in gene detection. The kit is an important part in a gene sequencing pretreatment device, and the kit in the prior art generally stores various samples, generally adopts a totally enclosed structure, is troublesome to operate, has a small application range and is high in cost.

SUMMERY OF THE UTILITY MODEL

The present application provides an open type reagent cartridge and a reagent detection device, wherein the open type reagent cartridge can enable a first accommodating hole and a second accommodating hole to be kept in an open state when a flip cover is closed through an opening position arranged on the flip cover.

The embodiment of the application is realized as follows:

in a first aspect, the present application provides an open kit comprising: the reagent box comprises an outer frame, a reagent tray, an outer support frame and a turnover cover, wherein the outer frame is provided with an accommodating space; the reagent tray is arranged in the accommodating space, and a plurality of first accommodating holes are formed in the top surface of the reagent tray; the outer support frame is connected with the outer frame and is arranged at intervals with the reagent tray, an outer mounting box is arranged on the outer support frame, and at least one second accommodating hole is formed in the top surface of the outer mounting box; the turning cover can be rotatably connected to the outer frame, and an opening position is arranged on the turning cover; when the flip cover is arranged on the reagent tray and the outer support frame, the first accommodating hole and the second accommodating hole are configured to be in an open state through the open position.

In one embodiment, the outer frame comprises a first frame and a second frame, and the first frame and the second frame are arranged at intervals to form an accommodating space; the top surface of the second frame is provided with a mounting groove, and the inner wall of the mounting groove is provided with at least one elastic plunger; one end of the bottom surface of the flip cover is hinged to the top surface of the first frame, the other end of the bottom surface of the flip cover is provided with a connecting buckle matched with the mounting groove, and the connecting buckle is provided with a clasp used for forming buckling fit with the elastic plunger.

In one embodiment, a positioning groove is formed on the top surface of the second frame and is positioned at the mounting groove; the bottom surface of the flip cover is provided with a positioning bulge matched with the positioning groove, and the connecting buckle is arranged on the positioning bulge.

In one embodiment, the top surface of the flip cover is provided with a handle.

In one embodiment, the plurality of first receiving holes includes: at least one test tube well, at least one thermal cover well, at least one first reaction well, at least one second reaction well, and a plurality of reagent wells.

In one embodiment, the plurality of reagent wells are distributed in an array; the test tube storage hole is positioned between the reagent hole and the outer support frame; the thermal cover storage hole, the first reaction hole and the second reaction hole are all positioned between the second frames of the reagent holes. The capacity of the first reaction well is smaller than the capacity of the second reaction well.

In one embodiment, the open bit comprises: at least one first open hole, at least one second open hole, and at least one third open hole, the first open hole being configured to configure the reagent well, the first reaction well, the second reaction well, and the thermal cover storage well to be open; the second open hole is used for configuring the second accommodating hole into an open state; the third opening hole is used for arranging the test tube storage hole in an open state.

In one embodiment, the bottom aperture of each reagent well is tapered.

In one embodiment, the reagent wells may be either square or circular in shape.

In one embodiment, the second receiving hole is used for storing the suction head cover or the thermal cover.

In one embodiment, the outer frame is provided with a tray in-place detection mechanism.

In one embodiment, the open kit further comprises: the storage rack is provided with an outer frame, a reagent tray and an outer support frame;

wherein, the bottom of outer mounting box is protruding to be located outer support frame, is equipped with the first through-hole that corresponds with outer mounting box on the supporter.

In a second aspect, the present application provides a reagent detection device comprising: the kit comprises a case and an open kit, wherein the open kit is the open kit of any embodiment, and is arranged in the case; wherein, an ultraviolet lamp is arranged in the case; the case is provided with a ventilation hole, and a filtering device is arranged at the ventilation hole.

Compared with the prior art, the beneficial effect of this application is:

the open type reagent kit can enable the first accommodating hole and the second accommodating hole to be kept in an open state when the flip cover covers through the open position arranged on the flip cover; when the device is applied to a reagent detection device, only one open type reagent kit works, and the case is sealed by matching the ventilation device arranged at the ventilation hole with the ultraviolet lamp for disinfection, so that the pollution among samples is avoided; in addition, due to the adoption of the open type kit, when the liquid transfer device is used for taking liquid, a suction head and the like from the open type kit, the liquid transfer device can be directly operated without frequently opening the turnover cover, so that the procedures are saved, the working efficiency is high, the application range is wide, and the cost is reduced.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present application and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained from the drawings without inventive effort.

Fig. 1 is a schematic structural diagram of a reagent detection device according to an embodiment of the present application.

Fig. 2 is a schematic structural diagram of an open kit according to an embodiment of the present application.

Fig. 3 is an exploded view of an open kit according to an embodiment of the present application.

Fig. 4 is a cross-sectional view of an open type reagent cartridge shown in an embodiment of the present application with a lid in an open state.

Fig. 5 is a cross-sectional view of an open type reagent cartridge shown in an embodiment of the present application with a lid in a closed state.

FIG. 6 is a top view of a reagent tray shown in an embodiment of the present application.

Fig. 7 is a sectional view taken along the line a-a of fig. 6 according to an embodiment of the present application.

Fig. 8 is a cross-sectional view taken along line B-B of fig. 6 according to an embodiment of the present application.

FIG. 9 is a cross-sectional view taken along the line C-C of FIG. 6, illustrating one embodiment of the present application.

FIG. 10 is a cross-sectional view taken in the direction of D-D of FIG. 6 illustrating one embodiment of the present application.

Icon: 1-a reagent detection device; 100-a chassis; 110-ultraviolet lamp; 120-a vent; 130-a filtration device; 140-a mobile device; 200-open kit; 210-an outer frame; 211-a first frame; 212-a second frame; 2121-mounting a groove; 2122-positioning the groove; 2123-a resilient plunger; 213-a containing space; 214-tray in-place detection mechanism; 2141-an elasticity detecting sheet; 220-a reagent tray; 221-a first receiving hole; 2211-test tube storage hole; 2212-hot lid storage hole; 2213-first reaction well; 2214-second reaction well; 2215-reagent well; a 1-general reagent zone; b 1-waste liquid zone; c 1-Trace reagent zone; d 1-Cold storage reagent zone; 230-outer support frame; 231-outer mounting box; 2311-a second receiving hole; 2312-first groove; 240-flip cover; 241-open position; 2411-a first open pore; 2412-a second open pore; 2413-a third open hole; 242-connecting fastener; 2421-clasp; 243-positioning protrusion; 250-a shelf; 251-a first through hole; 260-a handle; 300-a suction head sleeve; 310-a suction head; 320-a suction head sleeve fixing plate; 400-test tube with cover; 500-Hot lid.

Detailed Description

The terms "first," "second," "third," and the like are used for descriptive purposes only and not for purposes of indicating or implying relative importance, and do not denote any order or order.

Furthermore, the terms "horizontal", "vertical", "overhang" and the like do not imply that the components are required to be absolutely horizontal or overhang, but may be slightly inclined. For example, "horizontal" merely means that the direction is more horizontal than "vertical" and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.

In the description of the present application, it should be noted that the terms "inside", "outside", "left", "right", "upper", "lower", and the like indicate orientations or positional relationships based on orientations or positional relationships shown in the drawings or orientations or positional relationships that are conventionally arranged when products of the application are used, and are used only for convenience in describing the application and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the application.

In the description of the present application, unless expressly stated or limited otherwise, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements.

The gene detection is a medical detection technology, which extracts nucleic acid in peripheral venous blood, tissues and other body fluids of a detected person, analyzes DNA molecule or RNA molecule information in cells of the detected person through a detection device, so as to know the gene information of the detected person and further determine the cause of disease or the risk of disease. It should be understood that the gene detection is not limited to the detection of human body, but also includes the gene detection of animal and plant.

The nucleic acid extraction is a pretreatment process of gene detection, specific primers and probe design are carried out according to the sequence of known nucleic acid, the designed primers are synthesized, the extracted nucleic acid is used as a template to carry out a fluorescence quantitative PCR experiment, and the negative and positive of a target sample are judged according to a fluorescence signal. Nucleic acid extraction is a key step of gene detection, and the quality of the obtained nucleic acid directly influences the success or failure of downstream experiments.

The technical solution of the present application will be clearly and completely described below with reference to the accompanying drawings.

Please refer to fig. 1, which is a schematic structural diagram of a reagent detecting device 1 according to an embodiment of the present application. The reagent detecting device 1 includes: a case 100, wherein an open type reagent kit 200, an ultraviolet lamp 110 and a mobile device 140 are arranged in the case 100; one or more vents 120 are disposed on the housing 100, and a filtering device 130 is disposed at the vent 120. The filtering device 130 may be a High efficiency air Filter (HEPA).

The open type reagent cartridge 200 includes a flip 240, and a first receiving hole 221 and a second receiving hole 2311 for receiving reagents, test tubes, a thermal cap 500, a tip 310 and/or a tip holder 300, wherein the flip 240 is provided with an open position 241, as shown in fig. 1, the open type reagent cartridge 200 of the present embodiment can keep the first receiving hole 221 and the second receiving hole 2311 in an open state when the flip 240 is closed by the open position 241 provided on the flip 240.

Therefore, in this embodiment, only one open type reagent kit 200 works in one reagent detection device 1, and the case 100 is sterilized and sealed by the ventilation device arranged at the ventilation hole 120 and the ultraviolet lamp 110, so as to avoid contamination between samples; and because the open type kit 200 and the reagent detection device 1 are suitable for single sample detection, and a single sample can be detected at any time, the speed is high, the possibility of mutual pollution is avoided, the kit can be suitable for different reagent types on different occasions, and the pretreatment (nucleic acid extraction, gene library and PCR amplification reaction) of complete gene sequencing can be completed.

In addition, since the open type reagent kit 200 is adopted, when the liquid-taking, the suction head 310, the heat-taking cover 500 and the like are performed on the open type reagent kit 200 by the pipettor or the heating column in the moving device 140, the flip cover 240 does not need to be frequently opened, the operation can be directly performed, the procedures are saved, the working efficiency is high, the application range is wide, and the cost is reduced.

Please refer to fig. 2, which is a schematic structural diagram of an open kit 200 according to an embodiment of the present application. The open kit 200 includes: an outer frame 210, a reagent tray 220, an outer support frame 230 and a flip 240, wherein the outer frame 210 has a receiving space 213; the reagent tray 220 is disposed in the accommodating space 213, and a plurality of first accommodating holes 221 are formed in a top surface of the reagent tray 220; the outer support frame 230 is connected to the outer frame 210 and spaced from the reagent tray 220, an outer mounting box 231 is arranged on the outer support frame 230, and at least one second accommodating hole 2311 is formed in the top surface of the outer mounting box 231; the flip 240 is rotatably connected to the outer frame 210, and the flip 240 is provided with an open position 241.

In an operation process, the flip 240 is rotated to make the flip 240 in an open state, and at this time, the first receiving hole 221 and the second receiving hole 2311 are in an open state; when the lid 240 is rotated reversely to be in a closed state covering the reagent tray 220 and the outer support frame 230, the first accommodation hole 221 and the second accommodation hole 2311 are configured to be in an open state through the opening 241.

In this embodiment, the outer mounting box 231 and the outer support frame 230 are integrated, wherein the outer mounting box 231 and the outer support frame 230 can be detachably connected together by means of a snap connection or the like, so as to facilitate replacement and place other objects such as suction heads or heat covers with different sizes.

The open kit 200 further comprises: the shelf 250, the outer frame 210, the reagent tray 220 and the outer support frame 230 are all fixed on the shelf 250 by means of bolt connection and the like; the bottom of the outer mounting box 231 is convexly disposed on the outer support frame 230, the rack 250 is provided with a first through hole 251 corresponding to the outer mounting box 231, and the bottom of the outer mounting box 231 extends out of the first through hole 251.

In the open cassette 200, the usage of each of the first receiving hole 221 and the second receiving hole 2311 may be set by a user as needed, that is, in the case of using the layout of the first receiving hole 221 and the second receiving hole 2311 in the open cassette, the user may customize the usage of the hole sites according to a customized pre-gene sequencing flow.

Compared with the special kit in the prior art, the open kit 200 is not limited to one use method, has more use methods, and can be applied to various reagent schemes. Compared with a general kit such as a 96-well plate in the prior art, the open kit 200 has a certain special application, and a user can customize a hole site using mode according to a process before gene sequencing, so that the open kit 200 can carry out biochemical detection on a certain specific sample.

Please refer to fig. 3, which is an exploded view of an open kit 200 according to an embodiment of the present application. The outer frame 210 includes a first frame 211 and a second frame 212, and the first frame 211 and the second frame 212 are spaced apart from each other to form a receiving space 213 in which the reagent tray 220 is placed.

The second accommodation hole 2311 may be used to store the straw cap 300 or the hot cap 500. In this embodiment, the second receiving hole 2311 can store the pipette tip 310 and the pipette tip holder 300, the pipette tip 310 is isolated from each other to prevent contamination, and the second receiving hole 2311 is formed in the outer support frame 230 to eliminate the height limitation of the reagent tray 220. So that the manufacturing cost can be reduced.

Wherein, because the suction head 310 and the suction head cover 300 are disposable consumables, a suction head 310 can be wrapped in one suction head cover 300, and the independent packaging of the suction head 310 can prevent the pollution to other suction heads 310 caused by the arrangement of the suction head cover 300 after the use of the suction head 310 is completed.

In this embodiment, three second receiving holes 2311 are provided for respectively receiving one suction cap sleeve 300. The three pipette tip caps 300 are disposed on a pipette tip cap fixing plate 320, and the outer mounting case 231 is provided with a first groove 2312 matched with the pipette tip cap fixing plate 320. The pipette in the reagent detecting apparatus 1 can take away the tip 310 by the tension, and the reagent detecting apparatus 1 can further include a tip 310 retreating mechanism for retreating the tip 310 to the original position.

The plurality of first accommodation holes 221 include: at least one test tube storage hole 2211, at least one hot lid storage hole 2212, at least one first reaction hole 2213, at least one second reaction hole 2214, and a plurality of reagent holes 2215. Wherein, a plurality of reagent apertures 2215 are distributed in an array; the test tube access hole 2211 is located between the reagent hole 2215 and the outer support frame 230; the hot lid storage aperture 2212, the first reaction aperture 2213 and the second reaction aperture 2214 are all located between the second frame 212 of the reagent aperture 2215.

Wherein the thermal cover storage hole 2212 is located between the first reaction hole 2213 and the second reaction hole 2214. In another embodiment, the hot lid storage hole 2212 may be located at other positions on the reagent tray 220, not between the first reaction hole 2213 and the second reaction hole 2214.

In this embodiment, two test tube storage holes 2211 are provided for respectively storing one test tube 400 with a cap, the capacity of the test tube 400 with a cap may be 0.1mL to 0.2mL to increase universality, and one thermal cap storage hole 2212 is provided for storing one thermal cap 500. One first reaction hole 2213 is a micro-volume reaction hole and has heating and refrigerating functions, and a high-precision temperature sensor can be arranged at the first reaction hole 2213, so that high-precision thermal cycle control can be performed. The second reaction hole 2214 is provided with one, is a large-capacity reaction hole, has a bottom magnetism-absorbing function, a side magnetism-absorbing function and a heating function, and can carry out diversified magnetism-absorbing on magnetic beads. There are 28 reagent holes 2215.

The shape and number of the open positions 241 are related to the shape and number of the first and second receiving holes 221 and 2311. The open bit 241 includes: at least one first open hole 2411, at least one second open hole 2412, and at least one third open hole 2413, the first open hole 2411 being for disposing the reagent hole 2215, the first reaction hole 2213, the second reaction hole 2214, and the hot lid storage hole 2212 in an open state; the second open hole 2412 is used for configuring the second accommodation hole 2311 to be in an open state; the third opening 2413 is used to open the test tube storage hole 2211.

In this embodiment, one first open hole 2411 is provided, and the reagent hole 2215, the first reaction hole 2213, the second reaction hole 2214, and the thermal cover storage hole 2212 can be simultaneously arranged in an open state. The second open hole 2412 is a square hole, which can simultaneously configure 3 pipette tip caps 300 to be in an open state, and when the flip 240 is in a closed state, the flip 240 can press the pipette tip cap fixing plate 320. The third opening holes 2413 are provided two, and can respectively configure the test tubes 400 with covers in the 2 test tube storage holes 2211 in an open state, and when the folder 240 is in a closed state, the folder 240 can press the test tubes 400 with covers.

Referring to fig. 4, a cross-sectional view of the open type reagent kit 200 with the flip 240 in the open state is shown according to an embodiment of the present application. Referring to fig. 5, a cross-sectional view of the open type reagent kit 200 with the flip cover 240 in a closed state is shown according to an embodiment of the present application. A mounting groove 2121 is formed on the top surface of the second frame 212, and at least one elastic plunger 2123 is arranged on the inner wall of the mounting groove 2121; in this embodiment, two elastic plungers 2123 are provided. One end of the bottom surface of the flip 240 is hinged to the top surface of the first frame 211 by means of pin connection or the like, the other end is provided with a connecting buckle 242 matched with the mounting groove 2121, the connecting buckle 242 is provided with a clasp 2421, and the clasp 2421 is used for forming buckling fit with the elastic plunger 2123. The flip cover 240 is detachably connected with the elastic plunger 2123 through the clasp 2421, and the structure is simple and the operation is convenient.

A positioning groove 2122 is formed on the top surface of the second frame 212 at the mounting groove 2121; the bottom surface of the lid 240 is provided with a positioning protrusion 243 matching with the positioning groove 2122, and the connection buckle 242 is provided on the positioning protrusion 243. The positioning grooves 2122 and the positioning protrusions 243 may increase a contact area of the flip 240 with the second frame 212, so that the flip 240 is tightly connected with the second frame 212 in the closed state.

The top surface of the folder 240 is provided with a handle 260. The handle 260 may have various shapes such as a bar shape or a ball shape, and facilitates the opening and closing of the folder 240.

As shown in fig. 4, the tray-in-place detecting mechanism 214 is provided on the second frame 212 of the outer frame 210. The tray-in-position detecting mechanism 214 may be a deformation sensor or an optical sensor. In this embodiment, the tray in-place detection mechanism 214 is a deformation sensor, and when the reagent tray 220 is placed in the accommodating space 213, the elastic detection piece 2141 of the tray in-place detection mechanism 214 deforms, so that whether the reagent tray 220 is placed in the accommodating space 213 can be detected by the elastic detection piece 2141.

Please refer to fig. 6, which is a top view of the reagent tray 220 according to an embodiment of the present disclosure. Fig. 7 is a sectional view taken along the direction a-a of fig. 6 according to an embodiment of the present disclosure. Please refer to fig. 8, which is a cross-sectional view taken along the direction B-B of fig. 6 according to an embodiment of the present disclosure. Please refer to fig. 9, which is a cross-sectional view taken along the direction C-C in fig. 6 according to an embodiment of the present disclosure. Please refer to fig. 10, which is a cross-sectional view taken along the direction D-D of fig. 6 according to an embodiment of the present disclosure.

As shown in fig. 7; the bottom apertures of the first reaction hole 2213 and the second reaction hole 2214 are both tapered. And the bottom of the second reaction hole 2214 has a larger inclination angle, so that the liquid can slide down conveniently, and the liquid is less stored in the sharp head part at the bottom end and has considerable liquid level height. The hot lid storage hole 2212 is a stepped hole, and the bottom end of the stepped hole is closed, so that pollution to the outside of the open kit can be avoided.

The first and second reaction holes 2213 and 2214 have different capacities, and the capacity of the first reaction hole 2213 is smaller than that of the second reaction hole 2214, so that the capacity required for reactions with different amounts of reagents can be better satisfied. And first reaction hole 2213 and second reaction hole 2214 all have the reaction hole and contain the heating function, and second reaction hole 2214 more has the function of magnetism and inhales, and application scope is wider.

The hot cover 500 can be stored in the hot cover storage hole 2212, and the hot cover 500 can be used for preventing condensation and sealing aerosol in PCR amplification reaction, so that the pollution control effect is good.

The shape of the reagent hole 2215 may be either a square or a circle. In this embodiment, the reagent hole 2215 includes two types, namely a circular hole and a square hole, and can be divided into a general reagent area a1, a waste liquid area b1, a micro reagent area c1 and a refrigerated reagent area d1 as shown in fig. 6.

The bottom aperture of each reagent aperture 2215 is tapered. As shown in FIG. 8, the reagent hole 2215 in the normal reagent zone a1 is a square hole with a capacity of 2ml, and is mainly used for storing large-dose and non-valuable reagents. The bottom of the device is triangular prism-shaped, the sharp corner of the triangular prism is downward, so that the liquid reagent can flow to the middle, and most of the reagent can be taken away by the liquid shifter when the liquid is moved. As shown in FIG. 6, the reagent hole 2215 in the waste liquid region b1 can be composed of two square holes to have super capacity, and the shape is similar to the shape of the reagent hole 2215 in the ordinary reagent region a 1.

As shown in fig. 9, the reagent holes 2215 of the micro reagent area c1 and the refrigerated reagent area d1 have the same shape, except whether a refrigeration device is provided, such as: the refrigerated reagent zone d1 can be used for refrigerating temperature sensitive reagents such as enzymes and the like. The reagent hole 2215 in trace reagent district c1 and cold-stored reagent district d1 is the circular port, and its bottom sets up to big oblique angle circle end to make liquid reagent fall into the bottom more easily, and bottom liquid is enough little, can place the trace and cherish liquid, and the big oblique angle circle end of bottom can place the trace and cherish liquid, can place 5 microliters of liquid at minimum.

As shown in fig. 10, the test tube receiving hole 2211 is a circular hole, and the bottom aperture thereof is tapered and has a beveled rounded end to make it easier for the liquid reagent to fall to the bottom. The capped test tube 400 is in gapless long-distance fit with the test tube storage hole 2211, and the capped test tube 400 can be placed stably without shaking under the action of slight friction force. In the open kit, test tube storage hole 2211 can be deposited and is covered test tube 400, and the test tube 400 that covers is detachable, does benefit to the saving, and the result only needs 2 test tube storage holes 2211, more saves the position, and it is also more convenient to take.

To sum up, the open reagent kit of the present embodiment has a plurality of different and large accommodating holes, wherein the reagent hole 2215 of the reagent tray 220 can be divided into a plurality of different areas such as the general reagent area a1, the waste liquid area b1, the micro reagent area c1 and the refrigerated reagent area d1, so that the application range can be expanded, and the reagent kit can be applied to both the nucleic acid extraction type large reagent and the library construction type micro reagent, and the refrigerated reagent area d1 can be applied to the temperature sensitive reagent, and the product can be better preserved.

It should be noted that the features of the embodiments in the present application may be combined with each other without conflict.

The above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made to the present application by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims (10)

1. An open kit, comprising:

an outer frame having an accommodating space;

the reagent tray is arranged in the accommodating space, and a plurality of first accommodating holes are formed in the top surface of the reagent tray;

the outer support frame is connected to the outer frame and arranged at intervals with the reagent tray, an outer mounting box is arranged on the outer support frame, and at least one second accommodating hole is formed in the top surface of the outer mounting box;

the turnover cover is rotatably connected to the outer frame and is provided with an opening position;

when the flip cover is disposed on the reagent tray and the outer support frame, the first accommodating hole and the second accommodating hole are configured to be in an open state through the open position.

2. The open kit of claim 1, wherein the outer frame comprises a first frame and a second frame, the first frame and the second frame being spaced apart to form the receiving space;

the top surface of the second frame is provided with a mounting groove, and the inner wall of the mounting groove is provided with at least one elastic plunger;

one end of the bottom surface of the flip cover is hinged to the top surface of the first frame, a connecting buckle matched with the mounting groove is arranged at the other end of the bottom surface of the flip cover, and a clasp is arranged on the connecting buckle and used for being in lock joint fit with the elastic plunger.

3. The open kit of claim 2, wherein the top surface of the second frame is provided with a positioning groove at the mounting groove;

the bottom surface of the flip cover is provided with a positioning bulge matched with the positioning groove, and the connecting buckle is arranged on the positioning bulge;

the top surface of flip is equipped with the handle.

4. The open kit of claim 2, wherein the first plurality of receiving holes comprises: at least one test tube well, at least one thermal cover well, at least one first reaction well, at least one second reaction well, and a plurality of reagent wells; the second accommodating hole is a suction head sleeve mounting hole;

wherein, a plurality of reagent holes are distributed in an array;

the test tube storage hole is positioned between the reagent hole and the outer support frame;

the capacity of the first reaction hole is smaller than that of the second reaction hole;

the hot lid storage well, the first reaction well and the second reaction well are all located between the second frames of the reagent wells.

5. The open kit of claim 4, wherein the open position comprises: at least one first open hole, at least one second open hole and at least one third open hole,

the first open hole is used for configuring the reagent hole, the first reaction hole, the second reaction hole and the thermal cover storage hole into an open state;

the second open hole is used for configuring the second accommodating hole into an open state;

the third opening hole is used for arranging the test tube storage hole in an open state.

6. The open kit of claim 4, wherein the bottom aperture of each reagent well is tapered;

the reagent well may have a square or circular shape.

7. The open kit of claim 4, wherein the second receiving hole is for storing a pipette tip cap or a thermal cap.

8. The open kit of claim 1, wherein the outer frame is provided with a tray-in-place detection mechanism.

9. The open kit of any one of claims 1 to 7, further comprising:

the outer frame, the reagent tray and the outer support frame are arranged on the storage rack;

the bottom of the outer mounting box is convexly arranged on the outer support frame, and the article placing frame is provided with a first through hole corresponding to the outer mounting box.

10. A reagent testing device, comprising:

a chassis; and

an open kit according to any one of claims 1 to 9, the open kit being provided in the housing;

wherein an ultraviolet lamp is arranged in the case; the machine case is provided with a ventilation hole, and a filtering device is arranged at the ventilation hole.

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