CN217488951U - Mouse fixing device - Google Patents

Mouse fixing device Download PDF

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Publication number
CN217488951U
CN217488951U CN202120250859.3U CN202120250859U CN217488951U CN 217488951 U CN217488951 U CN 217488951U CN 202120250859 U CN202120250859 U CN 202120250859U CN 217488951 U CN217488951 U CN 217488951U
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China
Prior art keywords
mouse
box body
opening
lead plate
fixing device
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CN202120250859.3U
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Chinese (zh)
Inventor
陈柳尹
胡凯
黄卫妹
王厚圣
时智灵
陆玉双
范婷
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First Affiliated Hospital of Guangxi Medical University
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First Affiliated Hospital of Guangxi Medical University
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Abstract

The utility model discloses a mouse fixing device, which comprises a box body, a movable lead plate and a fixing frame, wherein one side of the box body is provided with an opening, at least one side of the box body is provided with an operation opening which can be opened and closed, and the bottom of the box body is provided with a heating component; the movable lead plate is plugged on the opening and can slide along the plane where the opening is located, and a hollowed-out area is formed in the movable lead plate; the fixing frame is arranged in the box body, and a plurality of fixing clamps are arranged on one side of the fixing frame, which is opposite to the opening. This mouse fixing device is provided with heating element on the box body, can guarantee the temperature in the whole box body, has reduced the influence of environment to the mouse, avoids disturbing the mouse. The operation port is convenient for workers to perform anesthesia or fixing operation on the mouse. The adjustment of different irradiation areas of the mouse can be realized by moving the movable lead plate, so that flexible radiation is realized; because the mouse is fixed on the fixing frame and is not moved in the irradiation process, the mouse is not easily disturbed, and the irradiation effect is convenient to improve.

Description

Mouse fixing device
Technical Field
The utility model relates to a radiobiology branch of academic or vocational study technical field especially relates to a mouse fixing device.
Background
Radiation therapy is an effective tumor treatment, but the tumor suppression effect of radiation therapy and the quality of life of patients are seriously affected by the damage of normal tissues caused by radiation therapy. Therefore, the evaluation of the damage of normal tissue caused by radiation is an important content of the radiobiological research, especially the skin reaction, and the skin is distributed on the surface and easy to observe, so that the evaluation of the damage of normal tissue caused by radiation is often used as an index.
At present, the radiation test is generally performed in animal experiments to evaluate and analyze the skin damage. Mice are often used as excellent animal test species due to their high human gene fitness and high reproductive capacity. In the radioactive experiment, the mouse has uncontrollable action because it belongs to a living animal, and therefore, some fixing structures are commonly used for fixing the four limbs of the mouse. For example, patent publication No. CN 205031385U-bare mouse radiotherapy fixing device for podocardial tumor discloses a fixing method, the fixing device includes several groups of unit drawer cases, each group of unit drawer cases includes a rectangular outer sleeve case and a rectangular drawing case, the drawing case is placed in the outer sleeve case to form a drawer structure, two end faces of the drawing case are closed, one end face is provided with a breathing hole, the other end face is provided with a leg stretching hole, the breathing hole is a circular hole, the leg stretching hole is a notch hole formed in the upper end of the end face of the drawing case, and the notch hole is a semicircular hole. The experimental mouse needs to be fixed in the radioactive experiment, but the above patent does not set any structure for fixing the mouse, and the box drawing and the mouse move together, so that the mouse is easy to frighten in the experiment process, and the behavior of the mouse is uncontrollable, thereby increasing the difficulty of the radioactive experiment and reducing the accuracy of the radioactive experiment, and therefore, the structure which can stably fix the mouse and reduce the frightening of the mouse in the radioactive experiment process is necessary.
Disclosure of Invention
The utility model provides a mouse fixing device, the mouse is difficult to frighten in this mouse fixing device experimentation, and the radiation is shone of high quality.
In order to realize the purpose, the utility model discloses a technical scheme be:
a mouse fixing device comprises a box body, a movable lead plate and a fixing frame, wherein an opening is formed in one side of the box body, an operation opening capable of being opened and closed is formed in at least one side of the box body, and a heating assembly is arranged at the bottom of the box body; the movable lead plate is blocked on the opening and can slide along the plane where the opening is located, and a hollow area is arranged on the movable lead plate; the fixing frame is arranged in the box body, and a plurality of fixing clamps are arranged on one side, opposite to the opening, of the fixing frame.
Further, be provided with the shutoff board on the mount, the fixation clamp sets up on the shutoff board.
Further, a sliding groove is formed in the opening, and the movable lead plate is slidably mounted in the sliding groove.
Further, the movable lead plate is provided with an adjusting block on the side of the periphery of the hollow area, the adjusting block is slidably mounted on the movable lead plate, and at least part of the adjusting block can block the hollow area.
Furthermore, a fixing pin is arranged on the movable lead plate, a guide groove matched with the fixing pin is formed in the adjusting block, a locking nut is arranged on the fixing pin and locks the adjusting block on the fixing pin, and a through hole is formed in the adjusting block.
Further, a handle is arranged at the top of the box body.
Further, the operation opening is arranged on the side wall of the box body on one side of the opening; and a sealing cover is arranged on the operation opening.
Furthermore, a sliding rail is arranged at the bottom inside the box body, the fixing frame is slidably mounted on the sliding rail, and the guiding direction of the sliding rail faces the operation opening.
Furthermore, a plurality of air holes are formed in the box body.
Furthermore, a heat preservation layer and a sound insulation layer are arranged in the box body.
Furthermore, a push-pull block is arranged on the movable lead plate.
The utility model has the advantages that:
this mouse fixing device is provided with heating element on the box body, can guarantee the temperature in the whole box body, has reduced the influence of environment to the mouse, avoids disturbing the mouse. In addition, the mouse can be conveniently anesthetized or fixedly operated by workers through the operation port. The adjustment of different irradiation areas of the mouse can be realized by moving the movable lead plate, so that flexible radiation is realized; meanwhile, the mouse is fixed on the fixing frame and is not moved in the irradiation process, so that the mouse is not easily disturbed, the behavior capability of the mouse is stable, and the radiation effect is convenient to improve.
Drawings
The following detailed description of embodiments of the invention is provided in conjunction with the accompanying drawings, in which:
fig. 1 is a first schematic structural diagram of an embodiment of the present invention;
fig. 2 is a schematic structural diagram ii according to an embodiment of the present invention.
In the figure: the box body 1, an opening 11, an operation opening 12, a heating component 13, a handle 14, a sealing cover 15, a slide rail 16, an air hole 17, a chute 18, a movable lead plate 2, a hollow-out area 21, an adjusting block 22, a push-pull block 23, a fixing pin 24, a guide groove 25, a locking nut 26, a through hole 27, a fixing frame 3, a fixing clamp 31 and a blocking plate 32
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts all belong to the protection scope of the present invention.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When a component is referred to as being "connected" to another component, it can be directly connected to the other component or intervening components may also be present. When a component is referred to as being "disposed on" another component, it can be directly on the other component or there can be intervening components, and when a component is referred to as being "disposed in the middle," it is not just disposed in the middle, as long as it is not disposed at both ends within the scope defined by the middle. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
Referring to fig. 1 to 2, the present application provides a mouse fixing device, which includes a box body 1, a movable lead plate 2 and a fixing frame 3, wherein an opening 11 is formed in one side of the box body 1, an operation opening 12 capable of being opened and closed is formed in at least one side of the box body 1, and a heating assembly 13 is arranged on the bottom of the box body 1; the movable lead plate 2 is blocked on the opening 11 and can slide along the plane where the opening 11 is located, and a hollow area 21 is arranged on the movable lead plate 2; the fixing frame 3 is arranged in the box body 1, and a plurality of fixing clamps 31 are arranged on one side of the fixing frame 3, which is opposite to the opening 11. Wherein, box body 1 adopts transparent material's plastics to make in this application, and the staff of being convenient for observes. The movable lead plate 2 can slide along any direction of the plane of the opening 11, but in practical use, the mouse is fixed and the whole body is small, so the movable lead plate 2 can slide along a given direction of the opening 11 in the application. The heating element 13 may be a conventional heating wire structure. In addition, the hollow-out area 21 may be a whole hollow-out hole, or may be a plurality of perforation structures distributed according to the corresponding positions of the conventional living organs, and in this application, the hollow-out area 21 is preferably a plurality of perforation structures distributed according to the corresponding positions of the conventional living organs.
In a modified embodiment, it is not easy to irradiate all the areas of the mouse if the mobile lead plate 2 is moved in only one direction, wherein, for better sliding, the mobile lead plate 2 is provided with a sliding slot 18 on the opening 11, and the mobile lead plate 2 is slidably mounted in the sliding slot 18. Furthermore, in order to better pull the mobile lead plate 2, a push-pull block 23 is provided on the mobile lead plate 2.
In another embodiment, in order to adjust the irradiation area more flexibly, the movable lead plate 2 is provided with an adjusting block 22 on the periphery of the hollow area 21, and the adjusting block 22 is slidably mounted on the movable lead plate 2 and at least partially blocks the hollow area 21. The range size of the hollow-out area 21 can be adjusted through the adjusting block 22, so that the size of the irradiated area of the mouse can be adjusted, and the irradiation flexibility is improved. In order to adjust the relative position of the adjusting block 22 and the hollow area 21 more easily, a fixing pin 24 is provided on the movable lead plate 2, a guide groove 25 matched with the fixing pin 24 is provided on the adjusting block 22, and a lock nut 26 is provided on the fixing pin 24, so that the adjusting block 22 is locked on the fixing pin 24 by the lock nut 26, and the position of the whole adjusting block 22 can be fixed. In actual use, the track of the guide groove 25 can be set according to actual use requirements, so that the adjusting block 22 can adjust the position of the adjusting block relative to the hollow area 21. In a preferred embodiment, the adjusting block 22 is further designed with a through hole 27, and when the actual position of the whole irradiation is adjusted, the adjustment can be achieved by adjusting the relative offset direction of the through hole 27 and the hollow area 21, which is simpler and more convenient. It should be noted that in the present application, the adjusting block 22 can always block all the areas where the hollow-out areas 21 are located no matter how the adjusting block is adjusted, and one hollow-out area 21 is kept to be completely overlapped or partially overlapped with the through hole 27. In the actual use, in order to improve the efficiency of work, can shine simultaneously a plurality of mice in same box body 1, for this reason in some embodiments, regulating block 22 can be provided with a plurality ofly, and fretwork district 21 also is provided with a plurality ofly simultaneously, can realize like this that the mode shines to many mice in the same irradiation process. If the operation is performed in the above manner, the movable lead plate 2 should be made of a lead material, so that redundant rays can be blocked and absorbed, and the tissue of the non-target area of the mouse can be prevented from being accidentally injured by the redundant rays passing through the movable lead plate 2.
Referring to fig. 2, a blocking plate 32 is arranged on the fixing frame 3, the fixing clip 31 is arranged on the blocking plate 32, and the blocking plate 32 can limit the swing of the mouse and has a limiting effect. The blocking plate 32 can be made of a lead plate, and the design can avoid that leaked rays are resisted by the blocking plate 32 and cannot penetrate through the box body 1 to be accidentally damaged when the irradiation position is adjusted to be wrong in the irradiation process.
Further, the operation port 12 is provided on a side wall of the box body 1 on the side of the opening 11; a sealing cover 15 is arranged on the operation opening 12; wherein the operation opening 12 is mainly convenient for the staff to take and put the mouse and beat operations such as anesthesia, and the closing cap 15 adopts articulated mode to install on the operation opening 12. In addition, a slide rail 16 is arranged at the bottom inside the box body 1, the fixed frame 3 is slidably mounted on the slide rail 16, and the guide direction of the slide rail 16 faces the operation opening 12. Therefore, the fixing frame 3 can slide out of the operation opening 12, and a worker can conveniently take and place and fix the mouse.
Referring to fig. 1 and 2, in order to better carry the present fastening device in the present application, the top of the box 1 is provided with a handle 14; in addition, a plurality of air holes 17 are formed in the box body 1, so that the mouse can ventilate conveniently. Because sound and the environment of the cloudy heavy cause the mouse to frighten easily, all be provided with heat preservation and puigging in the box body 1, the heat preservation can keep warm to whole box body 1 for box body 1 maintains at a suitable temperature, and the puigging can avoid radiating the produced sound of in-process and frightening the mouse, avoids the mouse to move with disorder and influence the radiation effect.
This mouse fixing device is provided with heating element 13 on box body 1, can guarantee the temperature in the whole box body 1, has reduced the influence of environment to the mouse, avoids disturbing the mouse. In addition, the operation port 12 can be used for facilitating the anesthesia or fixation operation of the mouse by workers. Wherein, the adjustment of different irradiation areas of the mouse can be realized by moving the movable lead plate 2, and the flexible radiation is realized; meanwhile, the mouse is fixed on the fixing frame 3 and is not moved in the irradiation process, so that the mouse is not easily disturbed, the behavior capability of the mouse is stable, and the radiation effect is convenient to improve.
The above embodiments are only used for illustrating the technical solutions of the present invention and are not limited thereto, and any modifications or equivalent replacements that do not depart from the spirit and scope of the present invention should be covered within the scope of the technical solutions of the present invention.

Claims (10)

1. A mouse fixing device is characterized by comprising
The box body is provided with an opening at one side, an operation opening capable of being opened and closed is arranged at least one side of the box body, and a heating assembly is arranged at the bottom of the box body;
the movable lead plate is blocked on the opening and can slide along the plane where the opening is located, and a hollow area is arranged on the movable lead plate; and
the fixing frame is arranged in the box body, and a plurality of fixing clamps are arranged on one side, opposite to the opening, of the fixing frame.
2. The mouse fixing device according to claim 1, wherein the fixing frame is provided with a blocking plate, and the fixing clip is provided on the blocking plate.
3. The mouse fixing device of claim 1, wherein the opening is provided with a sliding slot, and the movable lead plate is slidably mounted in the sliding slot.
4. A mouse fixing device according to claim 1 or 3, wherein the movable lead plate is provided with an adjusting block on the periphery of the hollow area, and the adjusting block is slidably mounted on the movable lead plate and at least partially blocks the hollow area.
5. The mouse fixing device according to claim 4, wherein the movable lead plate is provided with a fixing pin, the adjusting block is provided with a guide groove for matching with the fixing pin, a locking nut is arranged on the fixing pin, the locking nut locks the adjusting block on the fixing pin, and the adjusting block is provided with a through hole.
6. The mouse fixing device according to claim 1, wherein the operation port is provided on a side wall of the case body on the side of the opening; and a sealing cover is arranged on the operation opening.
7. The mouse fixing device according to claim 6, wherein a slide rail is disposed on the bottom inside the box body, the fixing frame is slidably mounted on the slide rail, and the guide direction of the slide rail faces the operation opening.
8. The mouse fixing device according to claim 1, wherein the box body is provided with a plurality of ventilation holes.
9. The mouse fixing device according to claim 1, wherein a heat insulation layer and a sound insulation layer are arranged in the box body.
10. The mouse fixing device of claim 1, wherein the moving lead plate is provided with a push-pull block.
CN202120250859.3U 2021-01-29 2021-01-29 Mouse fixing device Active CN217488951U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202120250859.3U CN217488951U (en) 2021-01-29 2021-01-29 Mouse fixing device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202120250859.3U CN217488951U (en) 2021-01-29 2021-01-29 Mouse fixing device

Publications (1)

Publication Number Publication Date
CN217488951U true CN217488951U (en) 2022-09-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202120250859.3U Active CN217488951U (en) 2021-01-29 2021-01-29 Mouse fixing device

Country Status (1)

Country Link
CN (1) CN217488951U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116650849A (en) * 2023-05-15 2023-08-29 中国人民解放军军事科学院军事医学研究院 Special fixing protection device for mouse radiotherapy and use method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116650849A (en) * 2023-05-15 2023-08-29 中国人民解放军军事科学院军事医学研究院 Special fixing protection device for mouse radiotherapy and use method
CN116650849B (en) * 2023-05-15 2024-03-22 中国人民解放军军事科学院军事医学研究院 Special fixing protection device for mouse radiotherapy and use method

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