CN217466416U

CN217466416U - Pathological biopsy tiny specimen collecting and embedding box

Info

Publication number: CN217466416U
Application number: CN202220295917.9U
Authority: CN
Inventors: 章文华; 董晓超; 田田; 孙丽娟
Original assignee: Hangzhou First Peoples Hospital
Current assignee: Hangzhou First Peoples Hospital
Priority date: 2022-02-14
Filing date: 2022-02-14
Publication date: 2022-09-20
Anticipated expiration: 2032-02-14

Abstract

The utility model discloses an embedding box is collected to small sample of pathological biopsy utilizes and can be solidified gradually by liquid for the embedding material of gel attitude, dewaters, the embedding to biological tissue sample, reduces the sample loss. The key points of the technical scheme are as follows: the device comprises an embedding box body and a box cover for sealing the embedding box body, wherein the box cover is connected with the embedding box body in a locking manner, a sample collecting bin is arranged in the embedding box body, a feeding port is formed in the top of the sample collecting bin, an seepage port is formed in the bottom of the sample collecting bin, a flow guide wall is arranged between the feeding port and the upper edge of the embedding box body, the feeding port is lower than the upper edge of the embedding box body, and the flow guide wall is an inclined wall gradually reduced from the periphery to the feeding port; the lid inboard is equipped with the pressure board, and when the lid covered tightly on the embedding box body, the pan feeding mouth in sample collection storehouse was sealed completely to the pressure board.

Description

Pathological biopsy tiny specimen collecting and embedding box

Technical Field

The utility model relates to a medical supplies technical field specifically is a miniature sample of pathology biopsy collects embedding box.

Background

With the rapid development of medical imaging technology, various minimally invasive diagnosis and treatment operations such as ultrasonic positioning puncture, endoscopic biopsy and the like are developed clinically. However, in order to reduce the bleeding and other side injuries in the puncture and biopsy operations, the selection of the puncture needle and the biopsy forceps is more and more elaborate, which results in small volume and small quantity of the obtained samples, and the sample loss is inevitable in the collection and manufacturing process of the tiny samples, thus further increasing the difficulty and the challenge for the later pathological diagnosis. Therefore, how to preserve as many tissue cells as possible under the condition of small specimen obtaining amount so as to improve the accuracy of pathological diagnosis becomes a clinical problem to be solved urgently.

The collection and the processing of the small sample of traditional pathology biopsy adopt formalin fixation, then all empty the sample and put into the dehydration on filter paper in the embedding box, the wax dipping, some tiny tissue blocks may directly run off because of empting the improper operation in this in-process, still some samples become littleer because of the dehydration, position dispersion on filter paper, probably be unfavorable for naked eye identification, it is very limited to cause the embedding in-process finally to remain the sample that is used for reading the piece diagnosis, it is also relatively not enough to do the usable sample of immunohistochemistry or molecular detection in the later stage, bring the difficulty for the accurate diagnosis of pathology.

SUMMERY OF THE UTILITY MODEL

The utility model aims at the problem that exists among the above-mentioned background art, provide a tiny sample of pathology biopsy (hereinafter referred to as "sample") and collect the embedding box, utilize and can solidify gradually by liquid for solid-state embedding material, convenient, swiftly collect the sample, reduce the sample loss under the prerequisite that does not influence the dehydration effect.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

a pathological biopsy tiny specimen collecting and embedding box comprises an embedding box body and a box cover used for sealing the embedding box body, wherein the box cover is connected with the embedding box body in a locking mode, a specimen collecting bin is arranged inside the embedding box body, the top of the specimen collecting bin is a feeding opening, the bottom of the specimen collecting bin is an seepage opening, a flow guide wall is arranged between the feeding opening and the upper edge of the embedding box body, the feeding opening is lower than the upper edge of the embedding box body, and the flow guide wall is an inclined wall gradually reduced from the periphery to the feeding opening; the lid inboard is equipped with the pressure board, and when the lid covered tightly on the embedding box body, the pan feeding mouth in sample collection storehouse was sealed completely to the pressure board.

Preferably, the box cover is provided with a sinking convex wall, the sinking convex wall is formed by extending the edge of the inner side of the box cover to the edge of the sealing and pressing plate, and when the box cover is tightly covered on the embedding box body, the sinking convex wall is tightly attached to the flow guide wall.

Preferably, a water absorption cushion layer is arranged in the seepage port of the specimen collection bin, and the water absorption cushion layer is made of porous water absorption materials.

Compared with the prior art, the pathological biopsy tiny specimen collecting and embedding box adopting the technical scheme has the following beneficial effects:

after the specimen is poured into the embedding box along with formalin solution, the specimen can flow into the specimen collecting bin along the flow guide wall, and the water absorption cushion layer can effectively overcome the surface tension of the liquid so that the solution can quickly seep out, and the specimen is left in the specimen collecting bin.

Second, the storehouse is collected to the sample in the cooperation this scheme, and the usable embedding material (like agar) that is solid-state by liquid solidification gradually is moulding to the sample, reduction sample loss that can be better. After liquid agar (temperature about 45 ℃) is added into the specimen collecting bin, the agar is closely attached to the specimen, then the box cover is fastened immediately, and the specimen can be molded after the agar is solidified, so that later-stage embedding is facilitated.

Preferably, the storehouse lateral wall is collected to the sample is equipped with a plurality of infiltration holes, embedding box body bottom fretwork, and the sample is collected and is communicate between storehouse lateral wall and the embedding box body bottom. The infiltration hole cooperation water absorption bed course can reach stronger infiltration ability, and the infiltration hole is set for enough little aperture according to the in-service use condition, can make liquid material such as formalin solution, alcohol and liquid paraffin fully permeate, nevertheless can not make the sample spill, and in addition, solution also has certain osmotic force in the agar, and with the dehydration effect that the sample can not be influenced to the sample moulding of agar.

Preferably, the box cover forms a sinking groove at the back side of the sinking convex wall, the sealing pressing plate is provided with a plurality of collecting holes, and after liquid agar is added into the specimen collecting bin, the redundant agar can also overflow upwards from the collecting holes and is stored in the sinking groove of the box cover.

Preferably, seal and press the panel surface middle part to be equipped with and be used for taking out the sample extraction structure in sample collection storehouse with the sample that the embedding was accomplished when uncapping.

Preferably, the sample taking-out structure comprises an embedded thin plate and an inward extending rod, the embedded thin plate is relatively fixed with the surface of the sealing and pressing plate through the inward extending rod, and when the box cover is tightly covered on the embedding box body, the embedded thin plate extends into the sample collecting bin from the feeding port.

Because the agar can stick the tiny tissues, after the agar is solidified, the tiny tissues in the specimen collection bin can be taken out together by taking out the agar block, and the loss caused by manually picking the specimen during embedding is reduced; because the embedding material is stayed in the specimen collection bin after solidification and is difficult to take down, and probably lead to the embedded specimen impaired during the separation of exerting oneself, and the embedding sheet metal is coated in the embedding material, can pull out the agar-agar piece that has the tissue together from specimen collection bin when uncapping.

Drawings

Fig. 1 is a schematic structural view of the pathological biopsy micro-specimen collecting and embedding box of embodiment 1 of the present invention.

Fig. 2 is a schematic structural view of a fully opened state of the lid in embodiment 1.

Fig. 3 and 4 are schematic cross-sectional views of example 1.

Fig. 5 is a schematic structural view of the pathological biopsy micro-specimen collecting and embedding box of embodiment 2 of the present invention.

Reference numerals: 1. embedding a box body of the box; 10. a flow guide wall; 11. a slope; 2. a box cover; 20. sinking the convex wall; 21. sealing and pressing the plate; 210. a collection well; 3. a specimen collecting bin; 30. a feeding port; 31. an effusion port; 32. a penetration hole; 4. a water-absorbing cushion layer; 5. a specimen retrieval structure; 50. embedding a thin plate; 51. an inner extending rod.

Detailed Description

The present invention will be further described with reference to the accompanying drawings.

Example 1:

as shown in fig. 1 to 4, the embedding box is collected to small sample of pathological biopsy, including embedding box body 1 and the lid 2 that is used for sealing embedding box body 1, lid 2 and embedding box body 1 can lock the connection, 1 inside sample collection storehouse 3 that is equipped with of embedding box body, 3 tops in sample collection storehouse are

pan feeding mouth

30, 3 bottoms in sample collection storehouse are oozing out 31, be equipped with water conservancy diversion wall 10 between pan feeding mouth 30 and the 1 top edge of embedding box body, pan feeding mouth 30 is less than 1 top edge of embedding box body, water conservancy diversion wall 10 is by the skew wall that reduces gradually all around to pan feeding mouth 30.

The inner side of the box cover 2 is provided with a sinking convex wall 20 and a sealing plate 21, the sinking convex wall 20 is formed by extending the inner side edge of the box cover 2 to the edge of the sealing plate 21, when the box cover 2 is tightly covered on the embedding box body 1, the sealing plate 21 completely seals the feeding port 30 of the specimen collecting bin 3, and the sinking convex wall 20 is tightly attached to the guide wall 10.

When pouring into the formalin solution that carries the sample to sample collection storehouse 3, solution flows into sample collection storehouse 3 along water conservancy diversion wall 10 is automatic, can avoid solution outflow to lead to the sample loss, convenient operation.

Be equipped with water absorption bed course 4 in the infiltration mouth 31 of storehouse 3 is collected to the sample, water absorption bed course 4 adopts porous water absorbing material, like the sponge, and the sample is poured into sample collection storehouse 3 along with formalin solution, because water absorption bed course 4's effect makes formalin solution can ooze fast, and leaves the sample completely and place in sample collection storehouse 3, conveniently collects the sample.

3 lateral walls in storehouse are collected to the sample are equipped with a plurality of infiltration holes 32, and the fretwork of 1 bottom of embedding box body, and the regional cavity between 3 lateral walls in storehouse and the water conservancy diversion wall 10 is collected to the shell body of embedding box body 1, sample for intercommunication between 3 lateral walls in storehouse and the 1 bottom of embedding box body is collected to the sample, and the liquid that oozes from infiltration holes 32 can be followed the outflow of 1 bottom of embedding box body.

The permeation hole 32 is set to a sufficiently small diameter according to actual use conditions, and the solution can be sufficiently permeated but the specimen cannot be leaked out.

The box cover 2 forms a sinking groove at the back side of the sinking convex wall 20, the sealing plate 21 is provided with a plurality of collecting holes 210, the aperture size of the collecting holes 210 is the same as that of the permeation holes 32 on the sample collecting bin 3, and after liquid agar is added into the sample collecting bin 3, the redundant agar can also overflow upwards from the collecting holes 210 and be stored in the sinking groove of the box cover 2.

In the in-service use process, pour the sample into sample collection storehouse 3 in the back, also can collect storehouse 3 to the sample and add a sponge, and agar is not added, and the sponge can cover on the sample, makes the sample concentrate on the bottom in sample collection storehouse, treats dehydration, soaks the wax after, the embedding is chosen to the manual work.

Example 2:

as shown in fig. 5, the technical content of this embodiment is basically the same as that of embodiment 1, and the technical points of this embodiment and embodiment 1 are as follows:

the specimen taking-out structure 5 that the storehouse 3 was collected to the specimen that will embed was accomplished was taken out in the middle part of the holding down plate 21 surface when being used for uncapping, specimen taking-out structure 5 is including embedding thin plate 50 and interior pole 51 that stretches out, embedding thin plate 50 is through stretching out pole 51 and holding down plate 21 surface relatively fixed in, when lid 2 lid was tightly on the embedding box, embedding thin plate 50 is stretched into in storehouse 3 is collected to the specimen by pan feeding mouth 30, embedding thin plate 50 is wrapped up by agar, after agar solidifies, embedding thin plate 50 is fixed in the agar block, open lid 2 this moment and can take out from the storehouse 3 is collected to the agar block that is inlaying the specimen.

The above is the preferred embodiment of the present invention, and for those skilled in the art, without departing from the principle of the present invention, several modifications and improvements can be made, and these should also be regarded as the protection scope of the present invention.

Claims

1. The utility model provides a little sample of pathology biopsy collects embedding box which characterized in that: the device comprises an embedding box body (1) and a box cover (2) used for sealing the embedding box body (1), wherein the box cover (2) is connected with the embedding box body (1) in a locking manner, a specimen collecting bin (3) is arranged inside the embedding box body (1), the top of the specimen collecting bin (3) is a feeding port (30), the bottom of the specimen collecting bin (3) is an seepage port (31), a flow guide wall (10) is arranged between the feeding port (30) and the upper edge of the embedding box body (1), the feeding port (30) is lower than the upper edge of the embedding box body (1), and the flow guide wall (10) is an inclined wall gradually reduced from the periphery to the feeding port (30); the inner side of the box cover (2) is provided with a sealing plate (21), and when the box cover (2) is tightly covered on the embedding box body (1), the feeding hole (30) of the specimen collecting bin (3) is completely sealed by the sealing plate (21).

2. The microscopic specimen collecting and embedding box for pathological biopsy according to claim 1, wherein: lid (2) are equipped with and sink protruding wall (20), sink protruding wall (20) and form by the edge extension of inboard edge of lid (2) to holding down plate (21), when lid (2) lid is tight on embedding box body (1), sink protruding wall (20) and hug closely water conservancy diversion wall (10).

3. The tiny specimen collecting and embedding box for pathological biopsy according to claim 1, which is characterized in that: a water absorption cushion layer (4) is arranged in the seepage port (31) of the specimen collection bin (3), and the water absorption cushion layer (4) is made of porous water absorption materials.

4. The microscopic specimen collecting and embedding box for pathological biopsy according to claim 1, wherein: the lateral wall of the specimen collection bin (3) is provided with a plurality of penetration holes (32), the bottom of the embedding box body (1) is hollowed out, and the lateral wall of the specimen collection bin (3) is communicated with the bottom of the embedding box body (1).

5. The microscopic specimen collecting and embedding box for pathological biopsy according to claim 2, wherein: the box cover (2) forms a sunken groove at the back side of the sunken convex wall (20), and a plurality of collecting holes (210) are formed in the sealing and pressing plate (21).

6. The microscopic specimen collecting and embedding box for pathological biopsy according to claim 1, wherein: the middle part of the surface of the pressure sealing plate (21) is provided with a specimen taking-out structure (5) which is used for taking out the embedded specimen from the specimen collecting bin (3) when the cover is opened.

7. The microscopic specimen collecting and embedding box for pathological biopsy according to claim 6, wherein: the specimen taking-out structure (5) comprises an embedded thin plate (50) and an inner extending rod (51), the embedded thin plate (50) is relatively fixed with the surface of the sealing plate (21) through the inner extending rod (51), and when the box cover (2) is tightly covered on the embedding box body (1), the embedded thin plate (50) extends into the specimen collecting bin (3) through the material inlet (30).