CN217403892U - Sampling device for testing antioxidant activity of hyaluronic acid - Google Patents
Sampling device for testing antioxidant activity of hyaluronic acid Download PDFInfo
- Publication number
- CN217403892U CN217403892U CN202220236056.7U CN202220236056U CN217403892U CN 217403892 U CN217403892 U CN 217403892U CN 202220236056 U CN202220236056 U CN 202220236056U CN 217403892 U CN217403892 U CN 217403892U
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- CN
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- Prior art keywords
- sampling
- sampling tube
- hyaluronic acid
- push rod
- antioxidant activity
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000005070 sampling Methods 0.000 title claims abstract description 127
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title claims abstract description 29
- 229920002674 hyaluronan Polymers 0.000 title claims abstract description 29
- 229960003160 hyaluronic acid Drugs 0.000 title claims abstract description 29
- 230000003078 antioxidant effect Effects 0.000 title claims abstract description 21
- 238000012360 testing method Methods 0.000 title claims abstract description 19
- 239000007788 liquid Substances 0.000 claims abstract description 16
- 238000003756 stirring Methods 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 4
- 238000004891 communication Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 7
- 230000008569 process Effects 0.000 abstract description 5
- 238000007689 inspection Methods 0.000 abstract description 4
- 238000005213 imbibition Methods 0.000 abstract description 3
- 238000000605 extraction Methods 0.000 abstract description 2
- 239000000243 solution Substances 0.000 description 6
- 230000009471 action Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 description 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 description 1
- MBLBDJOUHNCFQT-LXGUWJNJSA-N N-acetylglucosamine Natural products CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 description 1
- AEMOLEFTQBMNLQ-WAXACMCWSA-N alpha-D-glucuronic acid Chemical compound O[C@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-WAXACMCWSA-N 0.000 description 1
- 238000013480 data collection Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 150000002016 disaccharides Chemical class 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229950006780 n-acetylglucosamine Drugs 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 235000013547 stew Nutrition 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Sampling And Sample Adjustment (AREA)
Abstract
The utility model discloses a hyaluronic acid is sampling device for anti-oxidant activity test belongs to inspection auxiliary device field, including the sampler barrel, sampler barrel inner chamber swing joint has the piston bush, the tip is equipped with push rod and sampling tube respectively under the piston bush, be equipped with reset spring between push rod and the sampler barrel, the sampling tube lateral surface is equipped with the spiral strip, the tip rotates under the sampler barrel and is connected with the sampling head, tip is the annular under the sampling head and has seted up the imbibition hole, the sampling head inner chamber upper end is connected with the movable sleeve through rotating, the helicla flute has been seted up to the inner side wall of movable sleeve, swing joint has the spiral strip in the helicla flute, be equipped with the gas cell between piston bush and the sampler barrel. According to the liquid sampling device, the operation steps can be simplified by realizing the extraction of the liquid to be detected through one-time pressing, the sampling efficiency is improved, the liquid disturbance can be automatically detected in the pressing process, and the sampling data acquisition accuracy for the hyaluronic acid antioxidant activity test is improved.
Description
Technical Field
The utility model relates to an inspection auxiliary device field, specificly relate to a hyaluronic acid is sampling device for antioxidant activity inspection.
Background
Hyaluronic acid, also known as hyaluronic acid, has a molecular formula of (C14H21NO11) N, and is a disaccharide glycosaminoglycan composed of D-glucuronic acid and N-acetylglucosamine. The active hyaluronic acid has better effect than common hyaluronic acid, hyaluronic acid has different molecular sizes, small molecular hyaluronic acid injected into skin can preserve moisture and replenish water, and large molecular hyaluronic acid injected into skin deep layer can fill. The hyaluronic acid injection does not cause wound, is safe and has no side effect.
At present, various sampling devices for testing the antioxidant activity of hyaluronic acid on the market have the defects of low practicability. In the sampling process, the medicine reagent may precipitate after standing for a long time, and the medicine reagent cannot be effectively stirred, so that the accuracy of subsequent sampling data is affected. In response, we propose a sampling device for testing antioxidant activity of hyaluronic acid.
SUMMERY OF THE UTILITY MODEL
1. Technical problem to be solved
The to-be-solved technical problem of the utility model is to provide a hyaluronic acid is sampling device for antioxidant activity test, it can solve the problem in the above-mentioned background art.
2. Technical scheme
In order to solve the problem, the utility model adopts the following technical proposal: the utility model provides a hyaluronic acid is sampling device for anti-oxidant activity test, includes the sampler barrel, sampler barrel inner chamber swing joint has the piston cover, the tip is equipped with push rod and sampling tube respectively on the piston cover lower tip, be equipped with reset spring between push rod and the sampler barrel, the sampling tube lateral surface is equipped with the spiral strip, tip rotates under the sampler barrel and is connected with the sampling head, the sampling head outside is equipped with stirs the tooth, tip is the annular under the sampling head and has seted up the imbibition hole, sampling head inner chamber upper end fixed mounting has the movable sleeve, the helicla flute has been seted up to the inner wall of movable sleeve, swing joint has the spiral strip in the helicla flute, be equipped with the gas cell between piston cover and the sampler barrel.
Preferably, the outer side surface of the sampling tube is provided with a communicating hole which is used for communicating with the inflatable bag.
Preferably, the reset spring is arranged in the inner cavity of the sampling tube, and the reset spring is movably sleeved on the push rod.
Preferably, the push rod and the sampling tube are collinear in center, and the push rod is arranged above the sampling tube.
Preferably, the lower end part of the sampling tube is opened, and the sampling tube is movably inserted into the inner cavity of the sampling head.
Preferably, the sampling head is communicated with the inner cavity of the sampling tube, and a sealing ring is arranged at the joint of the sampling head and the sampling tube.
Preferably, the air inflation bag is arranged on the lower end part of the inner cavity of the sampling tube, and the upper end part and the lower end part of the air inflation bag are respectively glued on the piston sleeve and the sampling tube.
3. Advantageous effects
The utility model relates to a hyaluronic acid is sampling device for antioxidant activity test sets up push rod and sampling tube through setting up in the sampling tube to set up reset spring and gas cell respectively outside push rod and sampling tube, reset spring's setting can assist the gas cell to reset, makes once press can realize the extraction to the liquid that detects, has simplified the operating procedure, has improved the efficiency of sampling; and the tooth is moved in stirring that sets up in the sample head outside, press to waiting to detect liquid sample time, the sampling tube inserts inside the sample head gradually, the spiral strip of locating the sampling tube outside constantly is at the inside helicla flute internal motion of movable sleeve, thereby when pressing, can realize the autogiration of sample head, the tooth of stirring through the sample head outside can disturb the liquid of waiting to take a sample, prevent to stew and produce the sediment for a long time, and lead to the not accurate condition of sample data to take place, the accuracy of sample data collection for the anti-oxidant activity inspection of hyaluronic acid has been improved.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive labor.
FIG. 1 is a schematic main sectional view of the present invention;
fig. 2 is an enlarged schematic view of the utility model at the position M;
FIG. 3 is a schematic view showing the expansion of the movable sleeve according to the present invention;
fig. 4 is a schematic top view of the present invention.
Reference numerals are as follows: 1. a sampling tube; 2. a push rod; 3. a piston sleeve; 4. a sampling tube; 5. a return spring; 6. a helical strip; 7. a communicating hole; 8. an air-filled bag; 9. a sampling head; 10. a movable sleeve; 11. a helical groove; 12. a liquid suction hole; 13. the teeth are plucked.
Detailed Description
To make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the attached drawings in the embodiments of the present invention are combined to clearly and completely describe the technical solution in the embodiments of the present invention, and obviously, the described embodiments are part of the embodiments of the present invention, rather than all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
In the description of the present invention, unless otherwise explicitly specified or limited, the terms "connected", "connected" and "fixed" are to be construed broadly, e.g., as being fixedly connected, detachably connected, or integrated; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
In the present disclosure, unless expressly stated or limited otherwise, the feature of the inlet "on" or "under" the second feature may comprise direct contact between the inlet and the second feature, or may comprise contact between the inlet and the second feature not directly but through another feature in between. Also, the terms "over," "above," and "above" the second feature include the inlet feature being directly above and obliquely above the second feature, or simply indicating that the inlet feature is higher in level than the second feature. The terms "under", "below" and "beneath" of an inlet feature encompass the inlet feature being directly under and obliquely below the second feature, or simply meaning that the inlet feature is less level than the second feature.
The technical solution of the present invention is further explained by the following embodiments with reference to the accompanying drawings.
The sampling device for testing the antioxidant activity of hyaluronic acid comprises a sampling cylinder 1, a piston sleeve 3 is movably connected to the inner cavity of the sampling cylinder 1, and an air-filled bag 8 is arranged between the piston sleeve 3 and the sampling cylinder 1, as shown in fig. 1-4. Wherein the outer diameter of the piston sleeve 3 is equal to the inner diameter of the sampling tube 1. The upper end and the lower end of the piston sleeve 3 are respectively provided with a push rod 2 and a sampling tube 4, the centers of the push rod 2 and the sampling tube 4 are collinear, and the push rod 2 is arranged above the sampling tube 4. The junction of push rod 2 and sampler barrel 1 is equipped with the sealing washer, can be in push rod 2 in sampler barrel 1 in-process of taking out and inserting the motion, inside the reduction air admission sampler barrel 1, ensured the accuracy of sample.
Wherein, be equipped with reset spring 5 between push rod 2 and sampler barrel 1, reset spring 5 locates the inner chamber of sampler barrel 1, and reset spring 5 activity cup joints on push rod 2. By arranging the return spring 5, when the push rod 2 is pressed downwards, the piston sleeve 3 moves from top to bottom in the sampling tube 1, and at the moment, the return spring 5 is stretched; after sampling, the push rod 2 can be automatically pulled to move from bottom to top in the inner cavity of the sampling tube 1 under the elastic resetting action of the reset spring 5, and the auxiliary inflatable bag 8 sucks liquid to be sampled.
The outer side surface of the sampling tube 4 is provided with a spiral strip 6, and the spiral strip 6 is annularly wound on the outer side of the sampling tube 4. The lower end of the sampling tube 1 is rotatably connected with a sampling head 9, the sampling head 9 is communicated with the inner cavity of the sampling tube 1, and a sealing ring is arranged at the joint of the sampling head 9 and the sampling tube 1. The tip is the annular and has seted up imbibition hole 12 under the sampling head 9, and end fixed mounting has movable sleeve 10 on the sampling head 9 inner chamber, and spiral groove 11 has been seted up to movable sleeve 10 inside wall, and swing joint has helical strip 6 in the spiral groove 11, and at the in-process of sampling tube 4 up-and-down motion, helical strip 6 remains the internal motion at spiral groove 11 throughout to it is rotatory to promote movable sleeve 10. After the movable sleeve 10 rotates, the fixed sampling head 9 arranged outside the movable sleeve 10 rotates, a plurality of stirring teeth 13 are arranged outside the sampling head 9, the stirring teeth 13 can continuously treat liquid disturbance of sampling in the rotating process of the sampling head 9, and sampling accuracy is guaranteed.
Wherein, the inflatable bag 8 is arranged at the lower end part of the inner cavity of the sampling tube 1, and the upper end part and the lower end part of the inflatable bag 8 are respectively glued on the piston sleeve 3 and the sampling tube 1. Through the flexible of gas cell 8, can be with the liquid suction gas cell 8 inside of waiting to take a sample. The outer side surface of the sampling tube 4 is provided with a communicating hole 7 which is communicated with an air inflation bag 8. The lower end part of the sampling tube 4 is opened, and the sampling tube 4 is movably inserted in the inner cavity of the sampling head 9.
The specific application process of the sampling device for the antioxidant activity test of the hyaluronic acid is as follows: the sampling device for testing the antioxidant activity of the hyaluronic acid comprises a piston sleeve 3 arranged at the upper end part of an inner cavity of a sampling tube 1 under the elastic action of a return spring 5 in an initial state, the sampling device is inserted into liquid to be sampled when the sampling device is used, a push rod 2 is manually pressed to be inserted into the inner cavity of the sampling tube 1, the piston sleeve 3 moves in the inner cavity of the sampling tube 1 from top to bottom, the return spring 5 is stretched, an air bag 8 is compressed, a sampling tube 4 is inserted into a sampling head 9 in the downward movement process of the push rod 2, a spiral strip 6 arranged on the outer side of the sampling tube 4 continuously moves in a movable sleeve 10 to drive the movable sleeve 10 to rotate, and due to the fixed connection mode of the movable sleeve 10 and the sampling head 9, the sampling head 9 rotates while the movable sleeve 10 rotates, so as to drive a toggle tooth 13 arranged on the outer side of the sampling head 9 to disturb the liquid to be sampled continuously, the acting force applied to the push rod 2 is cancelled, at the moment, the piston sleeve 3 moves from bottom to top in the inner cavity of the sampling tube 1 under the elastic resetting action of the reset spring 5, the inflatable bag 8 forms negative pressure, liquid to be detected is sucked into the sampling head 9 from the liquid suction hole 12 and enters the inflatable bag 8 through the communication hole 7 on the sampling tube 4, and the liquid is continuously sucked along with the continuous resetting of the inflatable bag 8.
The above embodiments are only used to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.
Claims (7)
1. The utility model provides a hyaluronic acid is sampling device for antioxidant activity test, includes sampling tube (1), its characterized in that: the inner cavity of the sampling tube (1) is movably connected with a piston sleeve (3), the upper end and the lower end of the piston sleeve (3) are respectively provided with a push rod (2) and a sampling tube (4), a return spring (5) is arranged between the push rod (2) and the sampling tube (1), the outer side surface of the sampling tube (4) is provided with a spiral strip (6), the lower end part of the sampling tube (1) is rotationally connected with a sampling head (9), the outer side of the sampling head (9) is provided with a stirring tooth (13), the lower end part of the sampling head (9) is annularly provided with a liquid sucking hole (12), a movable sleeve (10) is fixedly arranged at the upper end part of the inner cavity of the sampling head (9), a spiral groove (11) is arranged on the inner side wall of the movable sleeve (10), a spiral strip (6) is movably connected in the spiral groove (11), an inflatable bag (8) is arranged between the piston sleeve (3) and the sampling tube (1).
2. The sampling device for testing the antioxidant activity of hyaluronic acid as defined in claim 1, wherein the outer side of the sampling tube (4) is provided with a communication hole (7) for communicating with the balloon (8).
3. The sampling device for testing the antioxidant activity of hyaluronic acid as defined in claim 1, wherein the return spring (5) is disposed in the inner cavity of the sampling tube (1), and the return spring (5) is movably sleeved on the push rod (2).
4. The sampling device for testing the antioxidant activity of hyaluronic acid as claimed in claim 1, wherein the push rod (2) is collinear with the center of the sampling tube (4), and the push rod (2) is disposed above the sampling tube (4).
5. The sampling device for testing the antioxidant activity of hyaluronic acid as claimed in claim 1, wherein the lower end of the sampling tube (4) is open, and the sampling tube (4) is movably inserted into the inner cavity of the sampling head (9).
6. The sampling device for testing the antioxidant activity of hyaluronic acid as defined in claim 1, wherein the sampling head (9) is communicated with the inner cavity of the sampling tube (1), and a sealing ring is disposed at the connection between the sampling head (9) and the sampling tube (1).
7. The sampling device for testing the antioxidant activity of hyaluronic acid as defined in claim 1, wherein the air-filled bag (8) is disposed at the lower end of the inner cavity of the sampling tube (1), and the upper and lower ends of the air-filled bag (8) are respectively glued to the piston sleeve (3) and the sampling tube (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220236056.7U CN217403892U (en) | 2022-01-28 | 2022-01-28 | Sampling device for testing antioxidant activity of hyaluronic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220236056.7U CN217403892U (en) | 2022-01-28 | 2022-01-28 | Sampling device for testing antioxidant activity of hyaluronic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN217403892U true CN217403892U (en) | 2022-09-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202220236056.7U Expired - Fee Related CN217403892U (en) | 2022-01-28 | 2022-01-28 | Sampling device for testing antioxidant activity of hyaluronic acid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN217403892U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116298181A (en) * | 2023-05-16 | 2023-06-23 | 山西国新科莱天然气有限公司 | Detection device for sulfide in natural gas |
-
2022
- 2022-01-28 CN CN202220236056.7U patent/CN217403892U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116298181A (en) * | 2023-05-16 | 2023-06-23 | 山西国新科莱天然气有限公司 | Detection device for sulfide in natural gas |
| CN116298181B (en) * | 2023-05-16 | 2023-07-21 | 山西国新科莱天然气有限公司 | Detection device for sulfide in natural gas |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20220909 |