CN217377914U - Cell culture equipment - Google Patents
Cell culture equipment Download PDFInfo
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- CN217377914U CN217377914U CN202221228630.0U CN202221228630U CN217377914U CN 217377914 U CN217377914 U CN 217377914U CN 202221228630 U CN202221228630 U CN 202221228630U CN 217377914 U CN217377914 U CN 217377914U
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Abstract
The utility model discloses a cell culture equipment, include: the main shell comprises a pipeline installation panel, a centrifugal system placing groove and a waste liquid placing groove; the centrifugal system is used for separating and culturing cells, is arranged in the centrifugal system placing groove and comprises a cell culture container and an observation system for observing the cell culture condition, and the observation system is connected with a display device positioned on the outer side of the main shell; the pipeline conveying system comprises a driving device for driving fluid to flow and a plurality of pipelines for conveying the fluid, the pipelines are detachably mounted on the pipeline mounting panel, each pipeline is provided with a switch valve for controlling the on-off of the pipeline, and the pipelines are communicated with the cell culture container. The utility model provides a cell culture equipment can realize automatic cell culture process, reduces the manpower demand, improves the efficiency of cell preparation, reduces the experiment cost and the pollution control degree of difficulty.
Description
Technical Field
The utility model relates to a cell culture equipment technical field especially relates to a cell culture equipment.
Background
The existing cell culture process is usually completed in a complex cell therapy laboratory, a GMP factory needs to be independently constructed in the traditional laboratory, the construction period is long, and the construction cost is high. Secondly, the whole process of the existing cell preparation is completed by manual operation, so that more manpower is required, errors can occur in the manual operation process, the experiment efficiency is low, and meanwhile, the difficulty in pollution control is high.
Therefore, how to improve the efficiency of cell culture, reduce the difficulty of pollution control, and reduce the cost of experiments is a technical problem that needs to be solved by those skilled in the art.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model aims at providing a cell culture equipment can realize automatic cell culture process, reduces the manpower demand, improves the efficiency of cell preparation, reduces the experiment cost and the pollution control degree of difficulty.
In order to achieve the above purpose, the utility model provides a following technical scheme:
a cell culture apparatus comprising:
the centrifugal device comprises a main shell, a centrifugal system and a waste liquid storage tank, wherein the main shell comprises a pipeline mounting panel, a centrifugal system storage tank and a waste liquid storage tank;
the centrifugal system is used for separating and culturing cells, is arranged in the centrifugal system placing groove and comprises a cell culture container and an observation system for observing the cell culture condition, and the observation system is connected with a display device positioned outside the main shell;
the pipeline conveying system comprises a driving device for driving fluid to flow and a plurality of pipelines for conveying fluid, the pipelines are detachably mounted on the pipeline mounting panel, each pipeline is provided with a switch valve for controlling the on-off of the pipeline, and the pipelines are communicated with the cell culture container.
Preferably, the electric vehicle further comprises an electric box detachably mounted to the inner side of the main housing.
Preferably, the conduit for transporting the liquid is provided with a bubble sensor for detecting bubbles in the liquid.
Preferably, the drive means is a peristaltic pump.
Preferably, the on-off valve is a pinch valve.
Preferably, one side of each pinch valve is connected with an indicator light, and the indicator light is used for indicating the working state of the corresponding pinch valve.
Preferably, one or more hangers for hanging the liquid bag are arranged above the top of the main shell.
Preferably, the main housing is provided with one or more support rods for supporting the corresponding hangers, and the hangers are slidably connected to the support rods through sliders.
Preferably, the display device is a touch screen display.
Preferably, the centrifugal system placing groove and the waste liquid placing groove are both located in front of the pipe installation panel.
The utility model provides a cell culture equipment's theory of operation as follows:
liquid such as blood and culture solution is carried to centrifugal system in through pipeline conveying system, and carry gas such as oxygen and carbon dioxide in to centrifugal system, centrifugal system realizes the separation of cell after centrifuging cell culture solution, after the induced cultivation of a period of time, observe the cell culture condition in the cell culture container through observation system, and show the observation result in real time through display device, after the cell reaches target quantity, restart pipeline conveying system, with the cell suction in the centrifugal system to the target liquid bag, simultaneously, waste liquid in the culture process also can carry the waste liquid bag through pipeline conveying system.
It is visible, the utility model provides a cell culture equipment can realize automatic cell culture process, reduces the manpower demand, improves the efficiency of cell preparation, reduces the experiment cost and the pollution control degree of difficulty.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic perspective view of a cell culture apparatus according to an embodiment of the present invention;
FIG. 2 is a front view of a cell culture apparatus according to an embodiment of the present invention;
FIG. 3 is a left side view of a cell culture apparatus according to an embodiment of the present invention;
FIG. 4 is a right side view of a cell culture apparatus according to an embodiment of the present invention;
FIG. 5 is a rear view of a cell culture apparatus according to an embodiment of the present invention.
Wherein 101 is a main casing, 102 is a centrifugal system, 103 is a display device, 104 is a pipeline, 105 is a switch valve, 106 is a bubble sensor, 107 is a driving device, 108 is an indicator, 109 is a hanger, 110 is a slider, 111 is a support rod, 112 is a waste liquid placing groove, 113 is an adjustable support leg, 114 is a power supply port, 115 is a distribution box, 116 is a first rear cover, and 117 is a second rear cover.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1 to 5, the present invention provides a cell culture apparatus, including:
the main casing 101, the main casing 101 includes the pipeline installation panel, centrifugal system standing groove, waste liquid standing groove 112, the waste liquid standing groove 112 can be the stainless steel container used for placing the waste liquid in bags, the main casing 101 can also set up the power port 114 used for external power supply;
the centrifugal system 102, the centrifugal system 102 is used for separating and culturing cells, the centrifugal system 102 is arranged in the centrifugal system placing groove, so that the whole centrifugal system 102 can be conveniently dismounted and replaced, and the centrifugal system placing groove can be arranged at the left front part of the cell culture equipment. The centrifugal system 102 comprises a cell culture container and an observation system for observing the cell culture condition, the observation system is connected with a display device 103 positioned outside the main shell 101, the display device 103 can be fixed on the main shell 101 according to a certain proper angle, and can also be arranged on the main shell 101 through an angle adjusting device so as to adjust the angle of the display device 103 according to requirements, the display device 103 is also a main equipment unit of man-machine interaction so as to control a circuit system by combining software, and the display device 103 can be a touch screen display;
the pipeline conveying system comprises a driving device 107 for driving fluid to flow and a plurality of pipelines 104 for conveying fluid to convey the fluid to the centrifugal system 102, the driving device 107 can be a peristaltic pump, the connecting relationship between the pipelines 104 and other devices (such as respectively communicated with the centrifugal system 102 and a liquid bag) can be the same as that in the prior art, the key point of the scheme is the installation manner of the centrifugal system and the pipeline conveying system, the pipelines 104 are detachably installed on a pipeline installation panel to facilitate the replacement of the pipelines 104, each pipeline 104 is provided with an on-off valve 105 for controlling the on-off of the pipeline, the pipeline 104 is communicated with a cell culture container, and the on-off valve 105 can be a pinch valve.
The utility model provides a cell culture equipment's theory of operation as follows:
liquid such as blood, culture solution and the like is conveyed into the centrifugal system 102 through the pipeline conveying system, gas such as oxygen, carbon dioxide and the like is conveyed into the centrifugal system 102, the centrifugal system 102 separates cells after centrifuging the cell culture solution, after a period of induced culture, the cell culture condition in a cell culture container is observed through the observation system, the observation result is displayed in real time through the display device 103, when the cells reach the target number, the pipeline conveying system is started again, the cells in the centrifugal system 102 are sucked out to the target liquid bag, and meanwhile, waste liquid in the culture process can also be conveyed into the waste liquid bag through the pipeline conveying system.
It is visible, the utility model provides a cell culture equipment can realize automatic cell culture process, reduces the manpower demand, improves the efficiency of cell preparation, reduces the experiment cost and the pollution control degree of difficulty.
In a specific embodiment of the present invention, the cell culture apparatus may further include a distribution box 115, the distribution box 115 is detachably installed in the inner side of the main casing 101, the distribution box 115 is the most core module in the whole apparatus, and the power supply unit, the control unit, the lead wire and other internal core components may be uniformly deployed and installed.
In order to further optimize the above technical solution, the pipeline 104 for conveying liquid may further be provided with a bubble sensor 106 for detecting bubbles in the liquid, and the bubble sensor 106 is adapted to detect the air, bubbles, and foam levels in the liquid flowing in the pipeline. It will be understood by those skilled in the art that other sensors may be provided as required for detecting the corresponding data according to actual requirements.
In order to indicate the on-off state of the pinch valves, one indicator light 108 is connected to one side of each pinch valve, and the indicator light 108 is used for indicating the working state of the corresponding pinch valve. Generally, the on state of the light can be set to indicate that the valve is opened, and the off state of the light can be correspondingly set to indicate that the valve is closed, and the reverse can be also set, for example, the on state of the light indicates that the valve is closed, and the off state of the light indicates that the valve is opened.
To facilitate the fixing of the fluid bag, one or more hangers 109 for hanging the fluid bag are provided above the top of the main housing 101 to provide fixing points for the fluid bag.
Further, the main housing 101 is provided with one or more support bars 111 for supporting the corresponding hangers 109, and the hangers 109 are slidably connected to the support bars 111 through the sliders 110. The hanger 109 is supported by the support rod 111, and the height of the hanger 109 can be adjusted under the action of the slider 110, and then the height of the fixed point of the liquid bag can be adjusted, and the fixed point of the liquid bag can be adjusted to a proper height by a person skilled in the art according to requirements. The sliding block 110 can be slidably engaged with the supporting rod 111, and after being adjusted to a suitable height, the sliding block is locked at a corresponding height of the supporting rod 111 through a locking device, and the hanger 109 can be directly fixed on the sliding block 110.
Further, both the centrifugal system placing tank and the waste liquid placing tank 112 are located in front of the pipe installation panel. The centrifugal system placing groove and the waste liquid placing groove 112 are respectively positioned at the left side and the right side of the whole machine.
The rear portion of the main casing body 101 is detachably provided with a first rear cover 116 and a second rear cover 117, the first rear cover 116 and the second rear cover 117 are respectively located on the left side and the right side of the equipment, and are respectively used for installing and overhauling parts on the left side and the right side in the equipment, and meanwhile, the sealing of the equipment can be guaranteed.
In order to facilitate the height adjustment of the cell culture apparatus, the main housing 101 is provided with adjustable legs 113 for supporting, the height of the adjustable legs 113 is adjustable, and the height of the cell culture apparatus can be adjusted correspondingly by adjusting the height of the adjustable legs 113, so as to adjust the height of the cell culture apparatus to a suitable height for an operator.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. A cell culture apparatus, comprising:
the centrifugal device comprises a main shell, a centrifugal system and a waste liquid storage tank, wherein the main shell comprises a pipeline mounting panel, a centrifugal system storage tank and a waste liquid storage tank;
the centrifugal system is used for separating and culturing cells, is arranged in the centrifugal system placing groove and comprises a cell culture container and an observation system for observing the cell culture condition, and the observation system is connected with a display device positioned outside the main shell;
the pipeline conveying system comprises a driving device for driving fluid to flow and a plurality of pipelines for conveying fluid, the pipelines are detachably mounted on the pipeline mounting panel, each pipeline is provided with a switch valve for controlling the on-off of the pipeline, and the pipelines are communicated with the cell culture container.
2. The cell culture apparatus of claim 1, further comprising a power distribution box removably mounted to an inside of the main housing.
3. The cell culture apparatus according to claim 1, wherein the piping for transporting the liquid is provided with a bubble sensor for detecting bubbles in the liquid.
4. The cell culture apparatus of claim 1, wherein the drive device is a peristaltic pump.
5. The cell culture apparatus of claim 1, wherein the on-off valve is a pinch valve.
6. The cell culture apparatus of claim 5, wherein an indicator light is connected to one side of each pinch valve for indicating the operating status of the corresponding pinch valve.
7. The cell culture apparatus of claim 1, wherein one or more hangers for hanging a fluid bag are disposed above the top of the main housing.
8. The cell culture apparatus of claim 7, wherein the main housing is provided with one or more support rods for supporting the corresponding hangers, and the hangers are slidably connected to the support rods by sliders.
9. The cell culture apparatus of claim 1, wherein the display device is a touch screen display.
10. The cell culture apparatus according to any one of claims 1 to 9, wherein the centrifugation system placement tank and the waste liquid placement tank are both located in front of the piping installation panel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221228630.0U CN217377914U (en) | 2022-05-20 | 2022-05-20 | Cell culture equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221228630.0U CN217377914U (en) | 2022-05-20 | 2022-05-20 | Cell culture equipment |
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| Publication Number | Publication Date |
|---|---|
| CN217377914U true CN217377914U (en) | 2022-09-06 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221228630.0U Active CN217377914U (en) | 2022-05-20 | 2022-05-20 | Cell culture equipment |
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| CN (1) | CN217377914U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118064269A (en) * | 2024-04-18 | 2024-05-24 | 苏州欣协生物科技有限公司 | Full-automatic closed cell preparation all-in-one |
-
2022
- 2022-05-20 CN CN202221228630.0U patent/CN217377914U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118064269A (en) * | 2024-04-18 | 2024-05-24 | 苏州欣协生物科技有限公司 | Full-automatic closed cell preparation all-in-one |
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Effective date of registration: 20230907 Address after: Room B6, 2nd Floor, Building A, Haichuang Valley Industrial Park, No. 8 Yaogu Erheng Road, Phase II, Yaogu Industrial Park, National High tech Industrial Development Zone, Haikou City, Hainan Province, 570100 Patentee after: Hainan Jiusu Medical Technology Development Co.,Ltd. Address before: 570300 room a7-26, 5th floor, building a, business incubation center, Haikou national high tech Zone, Xiuying street, Xiuying District, Haikou City, Hainan Province Patentee before: Hainan Langke Biotechnology Co.,Ltd. |
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| TR01 | Transfer of patent right |