CN217277264U - Glass slide serialization dyeing apparatus - Google Patents

Glass slide serialization dyeing apparatus Download PDF

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Publication number
CN217277264U
CN217277264U CN202122990666.4U CN202122990666U CN217277264U CN 217277264 U CN217277264 U CN 217277264U CN 202122990666 U CN202122990666 U CN 202122990666U CN 217277264 U CN217277264 U CN 217277264U
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China
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dyeing
slide
liquid
loading
separating cylinder
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CN202122990666.4U
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许济蕾
周春华
王光岩
陈言婕
闫士举
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Ruinjin Hospital Affiliated to Shanghai Jiaotong University School of Medicine Co Ltd
University of Shanghai for Science and Technology
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Ruinjin Hospital Affiliated to Shanghai Jiaotong University School of Medicine Co Ltd
University of Shanghai for Science and Technology
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Abstract

The utility model relates to a slide dyeing device, in particular to a slide sequencing dyeing device, which comprises a box body, a dyeing part and a loading part, wherein the dyeing part and the loading part are arranged in the box body; the dyeing part comprises a plurality of liquid storage tanks and a liquid separating cylinder, the liquid storage tanks are respectively connected with the liquid separating cylinder through pipelines, and the top of the liquid separating cylinder is provided with a plurality of spray heads extending towards the inside of the liquid separating cylinder; the loading part is arranged in the liquid separation cylinder in a lifting and rotating manner and comprises a loading platform, a plurality of bosses are arranged on the loading platform, and slide grooves for placing slides are arranged at the tops of the bosses; the nozzle is disposed toward the slide groove of the loading portion. Compared with the prior art, the utility model discloses set up a plurality of dyeing districts, each dyeing district all is equipped with the shower nozzle that corresponds different dye liquors, arranges each slide in the solitary dyeing district under following the load table rotation to different shower nozzles to carry out the dyeing and the washing of many dye liquors according to the order of sequence through the mode of spraying, prevent effectively that dyeing sequence mistake or dye liquor from receiving the pollution and leading to the dyeing failure.

Description

Glass slide serialization dyeing apparatus
Technical Field
The utility model relates to a slide dyeing apparatus, concretely relates to slide serialization dyeing apparatus.
Background
After the slide is loaded with the test substance, it is usually necessary to stain the slide so that the component substances contained therein can be observed more clearly under a microscope. However, the dyeing operation performed at present is usually performed manually. The manual operation is more tedious, and the analysis is carried out after the dyeing is carried out through different dye solutions in sequence, and then the dyeing is washed by clear water and dried. The operation mode is not only complicated, but also the problems of dyeing failure caused by wrong dyeing sequence or poor dyeing quality caused by inaccurate dye liquor consumption and the like are easy to occur; in addition, the staining efficiency is poor, only one slide can be processed at a time, and in practical cases, the number of biopsy pathological slides is usually large, and the processing and analysis need to be performed in time.
Although the existing automatic slide dyeing device can simultaneously process a plurality of slides, most dyeing devices perform dyeing processing in a dip dyeing mode, although the usage amount of the dip dyeing mode can be controlled to be uniform, the dip dyeing mode also has the condition that dye liquor is easy to pollute, the detection result can be influenced after the dye liquor is polluted, and more seriously, all dyed samples can fail, sampling and dyeing need to be performed again, so that time and resources are wasted.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving at least one of the above problems and providing a slide sequencing dyeing apparatus, realizing correct, batch, automatic and quick dyeing treatment of cytopathology slides under pancreas puncture and similar application scenes.
The purpose of the utility model is realized through the following technical scheme:
a slide sequential dyeing device comprises a box body, a dyeing part and a loading part, wherein the dyeing part and the loading part are arranged in the box body;
the dyeing part comprises a plurality of liquid storage tanks and a liquid separating cylinder, the liquid storage tanks are respectively connected with the liquid separating cylinder through pipelines, and the top of the liquid separating cylinder is provided with a plurality of spray heads extending towards the inside of the liquid separating cylinder;
the loading part is arranged in the liquid separation cylinder in a lifting and rotating manner and comprises a loading platform, a plurality of bosses are arranged on the loading platform, and slide grooves for placing slides are arranged at the tops of the bosses;
the spray head is arranged towards the slide groove of the loading part.
Preferably, the loading part further comprises a screw rod, a first-stage stepping motor, a motor base and a second-stage stepping motor, the first-stage stepping motor is connected with the loading platform through the screw rod, and the first-stage stepping motor is matched with the second-stage stepping motor through the motor base. The first-stage stepping motor controls the loading platform to move up and down along the screw rod; the motor base is respectively fixed with the first-stage stepping motor and the second-stage stepping motor; and the second-stage stepping motor controls the loading platform to rotate around the screw rod, so that after the glass slide is loaded in the glass slide groove, the loading platform descends to a specified height through the first-stage stepping motor and is dyed after rotating to a specified position through the second-stage stepping motor, and after dyeing is finished, the loading platform ascends to a height suitable for a user to take out the glass slide through the first-stage stepping motor.
Preferably, divide the liquid section of thick bamboo be equipped with the staining area that the boss quantity equals, every staining area top is equipped with the shower nozzle that equals with the liquid storage tank quantity along circumference. Supposing that x slides need to be dyed at one time, x bosses and slide grooves are correspondingly arranged, and x dyeing areas are arranged, y liquids need to be used during dyeing, y liquid storage tanks are correspondingly arranged, x and y spray heads can be arranged on the liquid separating cylinder totally, and y spray heads can be arranged in each dyeing area, so that each spray head in the same dyeing area corresponds to one liquid storage tank, and mixed use cannot occur.
Preferably, x and y are integers of 2 or more.
Preferably, the liquid separating cylinder is further provided with liquid separating cylinder ports, the number of the liquid separating cylinder ports is equal to that of the liquid storage tanks, the liquid separating cylinder ports are connected with the liquid storage tanks through pipelines, the liquid separating cylinder ports are connected with the spray heads through pipelines inside the liquid separating cylinder, and liquid in the liquid storage tanks is conveyed to the corresponding spray heads through the liquid separating cylinder ports. For one dyeing area, different liquid storage tanks are connected to different spray heads, so that the slide can be sequentially dyed under the spray heads in sequence, and the liquids are provided with separate pipelines, so that mutual pollution can not occur; the slides can be simultaneously dyed in different dyeing areas for the whole liquid separation cylinder, and the dyeing process of each slide in each dyeing area is consistent.
Preferably, the flushing and dyeing part further comprises a pump, and the pump is arranged on a pipeline connecting the liquid storage tank and the liquid separating cylinder. The pump provides sufficient pressure and can control the flow rate and flow rate of the liquid.
That is to say, liquid in the liquid storage tank can get into the liquid separation barrel through pipeline and liquid separation barrel mouth under the effect of pump machine to the pipeline according to liquid separation barrel internal design gets into the shower nozzle that corresponds in each dyeing district. In each dyeing area, each spray head is connected with the corresponding liquid storage tank, so that each liquid can be sprayed out by different spray heads in the dyeing area, and the dye liquor pollution caused by mixing can be avoided; and each dyeing area is provided with the respective spray head, so that uniform dyeing can be carried out, and the condition that a single spray head sprays non-uniformly in a large range can not happen.
Preferably, the box body comprises a box body and a box body cover covering the box body, and a box bottom groove, a motor groove and a liquid separating barrel groove are formed in the box body; the liquid storage tank is clamped in the tank bottom groove, the loading part is clamped in the motor groove, and the liquid separating barrel is sleeved outside the liquid separating barrel groove. The arrangement of each groove body is beneficial to positioning when the device is installed, and also can be convenient for a user to disassemble and assemble when the device is replaced and maintained.
Preferably, the upper end of the liquid separating cylinder groove is provided with a clamping groove matched with the spray head; the liquid separating cylinder is characterized in that a waste liquid pool and a liquid discharging pipe are arranged in the liquid separating cylinder, the waste liquid pool is arranged below the loading part, one end of the liquid discharging pipe is connected with the waste liquid pool, and the other end of the liquid discharging pipe penetrates through the box body. Because the liquid separation barrel is sleeved outside the liquid separation barrel groove, the clamping groove which can be matched with the spray head is arranged on the liquid separation barrel groove, the positioning of the liquid separation barrel during installation can be effectively realized, and the spray head and the slide groove do not need to be positioned again after the liquid separation barrel is installed every time.
Preferably, a hollow part is arranged at the center of the loading platform, and the hollow part is communicated with a waste liquid pool; the slide groove is inclined towards the hollow part. The lower part of loading portion communicates the waste liquid pond to the slide groove also sets up an inclination, not only can make the dye liquor more comprehensive dye the slide when dyeing, can also make the waste liquid flow down the loading platform along the slide, and flow into the waste liquid pond through well kenozooecium, passes through fluid-discharge tube eduction gear afterwards again. The design can reduce the collection of waste liquid after dyeing, and the waste liquid cannot be discharged randomly; and because loading portion when dyeing, whole all is located the box, therefore the dye liquor can not splash to the box outside, not only reduces the pollution to the environment, also can reduce the pollution of environment to the slide.
Preferably, the lower end of the slide groove is provided with a baffle plate with a notch. On the basis of ensuring that the slide cannot slide off, the dye solution can be left on the loading platform along the slide groove, and accumulation cannot occur.
Preferably, the box cover is provided with a loading cover at the position of the loading part, the loading cover is provided with an opening for the boss to pass through, and the lower side of the loading cover is provided with an air drying module. Through the design, when the loading platform is lifted, only the lug boss is exposed out of the box body cover, so that a user can take down the slide conveniently, and the damage of the outside to the internal structure can be reduced. The air drying module on the lower side of the loading cover is used for drying by blowing after dyeing and cleaning are finished, and dyeing quality is improved.
Preferably, the box cover further comprises a through hole for penetrating through the liquid storage tank, a digital display module arranged on the surface of the box cover and a control module arranged on the lower side of the box cover, and the control module is electrically connected with the digital display module, the box body, the dyeing part and the loading part respectively. The digital display module can display the internal working condition, the liquid height in the liquid storage tank, the waste liquid height in the waste liquid tank and the like for a user; the control module is used for controlling the movement of each component in the device, such as the movement of a driving motor, so that the loading platform is lifted and rotated; the control module can also receive external instructions input by a user, such as the sequence of automatic dyeing or the number of steps of automatic dyeing and the like can be adjusted according to the requirement, and a temperature and humidity sensing system is loaded to acquire related information for reference; the through hole can facilitate the user to take out the liquid storage tank, and can assist the positioning of the liquid storage tank.
After the device is opened, a user arranges a plurality of slides to be tested on the device loading table, the loading table drives the slides to move to a working position, automatic dyeing is started, the loading table rotates to different spray heads to sequentially carry out dyeing treatment on various dye solutions, after dyeing and washing are finished, the device air-dries the slides, and finally the user takes down the treated slides to analyze, and can prepare to treat the next batch of slides.
The utility model discloses a theory of operation does:
the device is opened by a user, the loading platform rises to expose the box body, after the user places the slide in the slide groove, the loading platform descends to a set height, the loading platform rotates to a first dyeing position, the spray head positioned right above the position sprays out the first dye solution stored in the liquid storage tank to dye, the loading platform rotates to a second dyeing position after standing, the spray head positioned right above the position sprays out the second dye solution stored in the liquid storage tank to dye, the loading platform stands and continues to be carried out until dyeing and cleaning (same as a dyeing process) are finished, then the loading platform rotates to be same as an initial position, and the loading platform rises to expose the boss out of the box body, so that the user can take down the slide to complete dyeing operation.
Compared with the prior art, the utility model discloses following beneficial effect has:
1. the utility model discloses a device divide into a plurality of dyeing districts, and every dyeing district all is provided with the shower nozzle that corresponds different dye liquors, when dyeing, arranges each slide in solitary dyeing district respectively in, follows the mode that the loading platform is rotatory to spraying through the shower nozzle under the different shower nozzles and carries out the dyeing of many dye liquors according to the order of sequence and handle and wash, prevents effectively that dyeing sequence mistake or dye liquor from receiving the pollution and make the problem of final dyeing failure.
2. The device of the utility model is provided with a plurality of dyeing areas, and each dyeing area is provided with an independent spray head for dyeing, so that a plurality of slides can be dyed simultaneously; all steps and operations in the dyeing process are automatically controlled and processed through the control module, full automation of dyeing is achieved, a user only needs to place a slide into the slide groove and take out the slide after dyeing is completed, and the workload of the user is greatly saved; in addition, because the whole process is automatically controlled, the dye liquor consumption and the dyeing duration in the dyeing process can be accurately controlled, and the dyeing result with good consistency can be obtained. This device convenient to use is swift, and dyeing quality is good, and is efficient to can carry out simple change in order to carry out the adaptation according to the actual dyeing demand, be suitable for the use.
3. During dyeing, the whole loading part can be retracted into the box body, and the design mode can prevent dye liquor from splashing everywhere to pollute the experimental environment; and a waste liquid pool specially used for storing waste liquid and a liquid discharge pipe used for discharging the waste liquid are arranged below the loading platform, so that the waste liquid obtained in the steps of dyeing, cleaning and the like is collected, and the environmental pollution caused by direct discharge of the waste liquid can be prevented.
4. Through setting up multiple groove in bottom half, be favorable to the location when installation and maintenance, especially set up the draw-in groove with shower nozzle matched with in minute liquid cylinder groove upper end, make the position of minute liquid cylinder installation back shower nozzle fixed, need not to carry on the alignment and the location in shower nozzle and slide groove again.
5. The box body cover is provided with the digital display module and the control module, so that a user can conveniently and visually read the dye liquor in the internal liquid storage tank, the height of the waste liquid in the waste liquid tank and the internal working state, and the user can be timely reminded of operating when the dye liquor is too little or the waste liquid is too much; and can also be loaded with environmental parameters such as temperature, humidity, etc. to provide a reference.
Drawings
Fig. 1 is a perspective schematic view of the overall structure of embodiment 1 of the present invention;
fig. 2 is an exploded perspective view of embodiment 1 of the present invention;
fig. 3 is an exploded perspective view of the case according to embodiment 1 of the present invention;
fig. 4 is an exploded schematic view of a loading part according to embodiment 1 of the present invention;
fig. 5 is a schematic perspective view of a loading table according to embodiment 1 of the present invention;
fig. 6 is a schematic structural view of a loading lid according to embodiment 1 of the present invention;
fig. 7 is a schematic structural view of the device according to embodiment 1 of the present invention when the loading platform is lifted;
fig. 8 is a schematic structural view of a die-dyeing section according to embodiment 1 of the present invention;
fig. 9 is a schematic perspective view of the structure of the die-dyeing part according to embodiment 1 of the present invention;
fig. 10 is a schematic top view of a liquid separation barrel according to embodiment 1 of the present invention;
fig. 11 is a schematic side view of a liquid separation barrel according to embodiment 1 of the present invention;
fig. 12 is a schematic perspective view of a structure of a liquid separation barrel according to embodiment 1 of the present invention;
in the figure: 100-a box body; 101-a box body; 102-a case cover; 103-a loading lid; 104-a control module; 105-a digital display module; 106-a via; 107-opening a hole; 108-an air drying module; 109-separating liquid cylinder groove; 110-drain pipe; 111-motor slot; 112-waste liquid pool; 113-tank bottom tank; 114-a card slot; 200-a dyeing part; 201-liquid separation cylinder; 202-a spray head; 203-a separating tube port; 204-a pump; 205-a liquid storage tank; 206-a pipeline; 300-a loading section; 301-a loading table; 302-boss; 303-slide groove; 304-a screw rod; 305-a one-stage stepper motor; 306-a motor mount; 307-a secondary stepper motor; 401-slide.
Detailed Description
The present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.
Example 1
A slide sequential-dyeing apparatus, as shown in fig. 1 to 12, comprising a case 100, and a dyeing section 200 and a loading section 300 provided inside the case 100; the dyeing part 200 comprises a plurality of liquid storage tanks 205 and liquid separating cylinders 201, the liquid storage tanks 205 are respectively connected with the liquid separating cylinders 201 through pipelines 206, and the tops of the liquid separating cylinders 201 are provided with a plurality of spray heads 202 extending towards the insides of the liquid separating cylinders 201; the loading part 300 is arranged in the liquid separation cylinder 201 in a lifting and rotating manner, the loading part 300 comprises a loading platform 301, a plurality of bosses 302 are arranged on the loading platform 301, and a slide groove 303 for placing a slide 401 is arranged at the top of each boss 302; the shower head 202 faces the slide groove 303 on the loading part 300.
More specifically, in the present embodiment:
the staining process of the slide 401 needs 2 kinds of staining solutions and washing with clear water, so the liquid storage pool 205 is provided with 3: respectively a first liquid storage tank 205 filled with a first dye solution, a second liquid storage tank 205 filled with a second dye solution and a third liquid storage tank 205 filled with clean water, wherein each liquid storage tank 205 is independently arranged (not communicated with each other). The loading stage 301 is provided with 5 bosses 302, and as shown in fig. 5, simultaneous staining of 5 slides 401 can be performed simultaneously. As shown in fig. 8, the liquid separating cylinder 201 is divided into 5 dyeing regions, 3 spray nozzles 202 are arranged at the upper end of each dyeing region, 15 spray nozzles 202 are arranged at the top of the liquid separating cylinder 201, the spray nozzles are circumferentially arranged along the top of the liquid separating cylinder 201, the distance between the spray nozzles 202 in the same dyeing region is equal, the distance between the spray nozzles in adjacent dyeing regions is slightly larger than the distance between the spray nozzles 202 in the same dyeing region, and the spray nozzles 202 in each dyeing region are respectively used for spraying the first dye solution, the second dye solution and the clear water. In this embodiment, the liquid separation cylinders 201 are of a similar layered structure, and as can be seen from fig. 11, a liquid separation cylinder port 203 is respectively arranged below the three liquid separation cylinders 201, specifically, the leftmost liquid separation cylinder port 203 in fig. 11 is connected with the innermost liquid separation cylinder 201 and a third liquid storage pool 205 filled with clean water through a pipeline 206, the middle liquid separation cylinder port 203 is connected with the middle liquid separation cylinder 201 and a second liquid storage pool 205 filled with a second dye solution through a pipeline 206, and the rightmost liquid separation cylinder port 203 is connected with the outermost liquid separation cylinder 201 and the first liquid storage pool 205 filled with a first dye solution through a pipeline 206; the feeding pipe is arranged in each layer of liquid separating cylinder 201 to feed the dye liquor or the clear water to the corresponding spray head 202, so that each liquid (including the dye liquor and the clear water) has an independent channel and the spray head 202, and mutual pollution can not occur. Because the liquid separating cylinder 201 and the liquid storage tank 205 are positioned on the same plane, even the spray head 202 is higher than the liquid level in the liquid storage tank 205, a pump 204 is also arranged on the pipeline 206 between the liquid storage tank 205 and the liquid separating cylinder port 203, so as to smoothly ensure the delivery of the dye liquor and the clean water and control the flow speed and the flow of the liquid.
The loading part 300 further comprises a driving component for driving the loading platform 301 to move, and specifically comprises a screw rod 304, a first-stage stepping motor 305, a motor base 306 and a second-stage stepping motor 307, wherein the first-stage stepping motor 305 is connected with the loading platform 301 through the screw rod 304, and the first-stage stepping motor 305 is matched with the second-stage stepping motor 307 through the motor base 306. The first-stage stepping motor 305 controls the loading platform 301 to move up and down along the screw rod 304; the motor base 306 respectively fixes the first-stage stepping motor 305 and the second-stage stepping motor 307; the second-stage stepping motor 307 controls the loading platform 301 to rotate around the screw rod 304, so that after the slide 401 is loaded in the slide groove 303, the loading platform 301 is lowered to a designated height through the first-stage stepping motor 305, and is rotated to a designated position through the second-stage stepping motor 307 for dyeing, and after the dyeing is finished, the loading platform 301 is raised to a height suitable for a user to take out the slide 401 through the first-stage stepping motor 305. In this embodiment, the second-stage stepping motor 307 drives the loading platform 301 to rotate three times during the staining process, so as to perform the first staining, the second staining and the rinsing, and after the cleaning process is completed, the second-stage stepping motor 307 drives the loading platform 301 to rotate to the initial position again, so that the user can conveniently identify the sequence and the position of the slide 401.
The housing 100 is composed of a housing body 101 and a housing cover 102 covering the housing body 101, and a waste liquid pool 112 and a drain pipe 110 are provided in the housing 100, the waste liquid pool 112 is provided below the loading part 300, and collects waste liquid flowing down from the loading part 300, and when it is necessary to drain the waste liquid, the waste liquid pool 112 is drained through the drain pipe 110 connected thereto. For better use with the waste liquid tank 112, a hollow portion is formed in the center of the loading table 301 so that the width of the remaining circular ring is equal to the length of the boss 302, as shown in fig. 5, and the slide groove 303 is formed in a pattern having an inclination angle of about 30 ° which is inclined from the outside to the inside, so that the dyeing liquid and the clean water during dyeing flow from the slide groove 303 through the hollow portion into the waste liquid tank 112. In order to prevent the slide 401 from sliding off due to the inclination angle during the staining process, a baffle is arranged at the lower end of the slide groove 303, and a gap with the length of about 2/3 slide grooves 303 is arranged at the middle part of the baffle so as to prevent the liquid from accumulating through the liquid. A tank bottom groove 113, a motor groove 111 and a separating cylinder groove 109 are also arranged in the tank body 100; the liquid storage tank 205 and the pump 204 are clamped in the tank bottom groove 113, the loading part 300 is clamped in the motor groove 111, and the liquid separating cylinder 201 is sleeved outside the liquid separating cylinder groove 109, so that the positioning of each part is facilitated during the installation and maintenance of the device. In this embodiment, the waste liquid pool 112 is a concentric cylinder nested type, as shown in fig. 3, the waste liquid pool 112 is an annular space portion formed between two cylinders, the bottom of the inner cylinder is provided with a motor groove 111 for arranging a secondary stepping motor 307, the centers of the tops of the two cylinders are provided with holes 107 matching the diameter of the screw rod 304, and the screw rod 304 extends out of the holes. The upper end of the liquid separating cylinder groove 109 is also provided with the matched clamping grooves 114 according to the shape, size and distribution of the spray heads 202 of the liquid separating cylinders 201, and the spray heads can be installed according to corresponding positions during installation, so that the spray heads 202 and the slide grooves 303 can be prevented from being realigned and positioned after the installation is finished.
The box cover 102 is provided with a loading cover 103 at the position of the loading portion 300, the loading cover 103 is provided with an opening 107 for allowing the boss 302 to pass through, the boss 302 in this embodiment is selected to be rectangular, and therefore the opening 107 is also a rectangular opening 107. When the user places the slide 401 before the staining and the user takes out the slide 401 after the staining is completed, the boss 302 protrudes from the opening 107 without opening the case cover 102, which is convenient for the user to operate. An air drying module 108 is arranged on the lower side of the loading cover 103, and after being cleaned by clear water, the air drying module 108 is started to dry the slide 401, so that the dyeing quality is improved. The tank cover 102 is also provided with a through hole 106 through which the reservoir 205 passes, and if the reservoir 205 is provided with a transparent surface, the internal liquid level and the state of the liquid can be directly observed, and replacement of the reservoir 205 or addition of the liquid can be performed through the through hole 106. The upper surface of the box cover 102 is provided with the digital display module 105, the inner surface is provided with the control module 104, the control module 104 can control the operation of the loading part 300 and the dyeing part 200, and can also integrate the internal information of the device, such as temperature, humidity, liquid level height in the liquid storage pool 205, liquid level height in the waste liquid pool 112 and other parameters, and react the internal information on the digital display module 105, in particular, when the liquid level height in the liquid storage pool 205 is too low or the liquid level height in the waste liquid pool 112 is too high, the user can be prompted to operate through the digital display module 105, in addition, the control module 104 can also access external data or external programs, so that the user can adjust the parameters of the device during operation, such as standing time, liquid flow rate, rotation angle and the like.
When the staining apparatus of this embodiment is used, first, the apparatus is opened, the boss 302 will extend from the opening 107 of the loading lid 103 in the box 100, the user will place the slide 401 in the slide groove 303, when the loading platform 301 and the control module 104 detect that the slide groove 303 is full and correctly installed, or the user actively turns on the apparatus, the one-stage stepping motor 305 will be started to lower the loading platform 301 to a height suitable for spraying and staining, and after reaching the height, the rotation will be performed to align each slide groove 303 with the nozzle 202(1A) (see fig. 12, the 1A mark in the figure is only an example, actually, each staining area is provided with the nozzle 202(1A), and the same follows, even if each slide 401 is located under the nozzle 202 to be sprayed with liquid. And then, a pump 204 connected with the first liquid storage tank operates to send the first dye solution into the liquid separation barrel 201 from the liquid separation barrel port 203(5A) through a pipeline 206 at a set flow speed and flow rate, the first dye solution sequentially passes through the annular channel (4A), the short channel (3A) and the barrel wall channel (2A) in the liquid separation barrel 201 to reach the spray head 202(1A), the spray head 202(1A) sprays the dye solution, after the spraying is finished, the pump 204 stops working, and the redundant dye solution flows into the waste liquid tank 112 along with the slide groove 303. Standing for a period of time (which can be set according to different dyeing objects, such as 15s or 30s, and the like), fully dyeing for the first time, driving the loading platform 301 to rotate again by the secondary stepping motor 307, enabling the slide groove 303 to be aligned with the spray head 202(1B), operating the pump 204 connected with the second liquid storage tank, sending the second dye solution into the liquid separation cylinder 201 from the liquid separation cylinder port 203(5B) through the pipeline 206 at a set flow rate and flow rate, sequentially passing through the annular channel (4B), the short channel (3B) and the cylinder wall channel (2B) in the liquid separation cylinder 201 to reach the spray head 202(1B), spraying the spray head 202(1B) with the dye solution, stopping the pump 204 after spraying, and allowing the redundant dye solution to flow into the waste liquid tank 112 along with the slide groove 303. Standing for a period of time to fully dye the second time, driving the loading platform 301 to rotate again by the second-stage stepping motor 307 to enable the slide groove 303 to align with the spray head 202(1C), enabling the pump 204 connected with the third liquid storage tank to operate, sending the clear water into the liquid separation cylinder 201 from the liquid separation cylinder port 203(5C) through the pipeline 206 at the set flow speed and flow rate, enabling the clear water to sequentially pass through the annular channel (4C), the short channel (3C) and the cylinder wall channel (2C) in the liquid separation cylinder 201 to reach the spray head 202(1C), spraying the clear water by the spray head 202(1C), stopping the pump 204 after cleaning, and enabling the redundant clear water to flow into the waste liquid tank 112 along with the slide groove 303. After standing for a period of time, the air drying module 108 inside the loading cover 103 is started to dry the slide 401, then the second-stage stepping motor 307 rotates the loading platform 301 to return to the initial position, the first-stage stepping motor 305 lifts the loading platform 301 to the boss 302 to expose the loading cover 103, and the user takes out the slide 401. If the user continues to place a new slide 401 to be processed, the apparatus automatically repeats the above steps, and automatically returns to the initial state after the user finishes using the apparatus. Of course, this process is only one embodiment, and dyeing and rinsing may be performed in the order of 1C, 1B and 1A by rotating it in the reverse direction according to the setting.
The utility model discloses a theory of operation does:
when the user opens the apparatus, the loading platform 301 is raised to expose the box body 100, after the user places the slide 401 in the slide groove 303, the loading platform 301 is lowered to a set height, rotated to a first dyeing position, the spray head 202 positioned right above the position sprays the first dye solution stored in the liquid storage pool 205 for dyeing, after standing, the loading platform 301 is rotated to a second dyeing position, the spray head 202 positioned right above the position sprays the second dye solution stored in the liquid storage pool 205 for dyeing, standing is continued until dyeing and cleaning (same as a dyeing flow) are finished, then the loading platform 301 is rotated to be same as the initial position, and is raised to expose the boss 302 out of the box body 100, and the user can take off the slide 401 to finish the dyeing operation.
It should be noted that the present embodiment is only one of the exemplary embodiments, and is only used for illustrating the technical solution of the present invention, and not for limiting the same. While the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those skilled in the art that; it is also possible to modify the solutions described in the above embodiments or to substitute some or all of the technical features of them equally. Such modifications and substitutions do not depart from the spirit and scope of the embodiments of the present invention.
For example, in the present embodiment, for cytopathology staining treatment after fine needle puncture under guidance of an ultrasound endoscope for pancreatic lesion, three kinds of staining solutions can be used sequentially for staining, and the number of the liquid storage tanks 205, the pump 204, and the like can be adjusted according to actual needs, and the structure of the liquid distribution cylinder 201 and the number of the spray heads 202 can be adjusted in an analog manner.
The embodiments described above are intended to facilitate the understanding and use of the invention by those skilled in the art. It will be readily apparent to those skilled in the art that various modifications to these embodiments may be made, and the generic principles described herein may be applied to other embodiments without the use of the inventive faculty. Therefore, the present invention is not limited to the above embodiments, and those skilled in the art should make improvements and modifications within the scope of the present invention according to the disclosure of the present invention.

Claims (10)

1. A slide sequential staining device is characterized by comprising a box body (100), and a staining part (200) and a loading part (300) which are arranged in the box body (100);
the dyeing part (200) comprises a plurality of liquid storage tanks (205) and a liquid separating cylinder (201), the liquid storage tanks (205) are respectively connected with the liquid separating cylinder (201) through pipelines (206), and the top of the liquid separating cylinder (201) is provided with a plurality of spray heads (202) extending towards the interior of the liquid separating cylinder (201);
the loading part (300) is arranged in the liquid separation cylinder (201) in a lifting and rotating manner, the loading part (300) comprises a loading table (301), a plurality of bosses (302) are arranged on the loading table (301), and a slide groove (303) for placing a slide (401) is arranged at the top of each boss (302);
the nozzle (202) is disposed facing the slide groove (303) of the loading unit (300).
2. A slide sequential staining apparatus as claimed in claim 1, wherein the loading portion (300) further comprises a lead screw (304), a first step motor (305), a motor base (306), and a second step motor (307), the first step motor (305) is connected to the loading stage (301) through the lead screw (304), and the first step motor (305) and the second step motor (307) are coupled through the motor base (306).
3. A slide-ordering staining apparatus as claimed in claim 1, wherein the liquid-separating cylinder (201) has staining areas equal in number to the number of the bosses (302), and a number of the nozzles (202) equal in number to the number of the reservoirs (205) are provided at the top of each staining area in the circumferential direction.
4. A slide-sequencing staining apparatus according to claim 1 or 3, wherein the washing section (200) further comprises a pump (204), and the pump (204) is disposed on a pipe (206) connecting the reservoir (205) and the dispensing cylinder (201).
5. The slide sequential staining device of claim 1, wherein the box (100) comprises a box body (101) and a box cover (102) covering the box body (101), and a bottom tank (113), a motor tank (111) and a separating barrel tank (109) are arranged in the box (100); the liquid storage tank (205) is clamped in the tank bottom groove (113), the loading part (300) is clamped in the motor groove (111), and the liquid separating cylinder (201) is sleeved outside the liquid separating cylinder groove (109).
6. The device for sequentially dyeing the glass slides as claimed in claim 5, wherein the upper end of the liquid separating cylinder groove (109) is provided with a clamping groove (114) matched with the spray head (202); the liquid separating cylinder is characterized in that a waste liquid pool (112) and a liquid discharging pipe (110) are arranged in the liquid separating cylinder groove (109), the waste liquid pool (112) is arranged below the loading part (300), one end of the liquid discharging pipe (110) is connected with the waste liquid pool (112), and the other end of the liquid discharging pipe penetrates through the box body (101).
7. A slide sequential staining apparatus as claimed in claim 6, wherein the loading platform (301) has a hollow portion at the center, the hollow portion being connected to the waste liquid pool (112); the slide groove (303) is inclined towards the hollow part.
8. A slide sequential staining apparatus as claimed in claim 7, wherein the slide groove (303) is provided at a lower end thereof with a notched stopper.
9. The slide sequential staining device of claim 5, wherein the box cover (102) is provided with a loading cover (103) at the position of the loading part (300), the loading cover (103) is provided with an opening (107) for the boss (302) to pass through, and an air drying module (108) is arranged at the lower side of the loading cover (103).
10. The slide sequential staining device of claim 5, wherein the case cover (102) further comprises a through hole (106) for passing through the liquid storage tank (205), a digital display module (105) disposed on the surface of the case cover (102), and a control module (104) disposed on the lower side of the case cover (102), and the control module (104) is electrically connected to the digital display module (105), the case (100), the staining part (200), and the loading part (300), respectively.
CN202122990666.4U 2021-12-01 2021-12-01 Glass slide serialization dyeing apparatus Active CN217277264U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122990666.4U CN217277264U (en) 2021-12-01 2021-12-01 Glass slide serialization dyeing apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122990666.4U CN217277264U (en) 2021-12-01 2021-12-01 Glass slide serialization dyeing apparatus

Publications (1)

Publication Number Publication Date
CN217277264U true CN217277264U (en) 2022-08-23

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Application Number Title Priority Date Filing Date
CN202122990666.4U Active CN217277264U (en) 2021-12-01 2021-12-01 Glass slide serialization dyeing apparatus

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