CN217112169U - Portable quick biomacromolecule magnetoelectric double-acting separation equipment - Google Patents
Portable quick biomacromolecule magnetoelectric double-acting separation equipment Download PDFInfo
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- CN217112169U CN217112169U CN202123299494.2U CN202123299494U CN217112169U CN 217112169 U CN217112169 U CN 217112169U CN 202123299494 U CN202123299494 U CN 202123299494U CN 217112169 U CN217112169 U CN 217112169U
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Abstract
The utility model discloses a portable rapid biomacromolecule magnetoelectric double-acting separation device, which comprises a shell, wherein an electrophoresis tank is arranged in the shell; a plate body is arranged in the electrophoresis tank, gel is arranged on the plate body, and the plate body and the gel are divided into a plurality of segmentation areas; the inner surface of the shell is provided with a control box and a magnetic field sub-control box; a power switch and a power relay are arranged in the control box; a magnetic field relay and a tapping line bar are arranged in the magnetic field tapping control box; the two opposite inner surfaces of the shell are provided with movable mounting components, the movable mounting components are provided with electric field generators and magnetic field generators, and the electric field generators and the magnetic field generators correspond to all the segmentation areas. The utility model discloses fill the linear motion who guarantees the macromolecule, the condition of skew can not appear, and equipment overall design is reasonable, simple structure, small and exquisite light, conveniently carries and transport, and the in-service use is effectual.
Description
Technical Field
The utility model relates to a biomacromolecule splitter field particularly, relates to a two effect splitter of portable quick biomacromolecule magnetoelectric.
Background
The electrophoresis tank is commonly used for the separation experiment of biological macromolecules in biomedicine, and the principle is as follows: the terminals of the electrophoresis tank comprise a positive electrode and a negative electrode, and the positive electrode and the negative electrode are respectively connected with a positive output end and a negative output end of a direct current power supply. The anode electrode in the electrophoresis tank, various gels with a space grid steric hindrance structure, the cathode electrode in the electrophoresis tank, the immersed gel cathode end and the electrophoresis tank cathode electrode, and the immersed gel anode end and the buffer solution with the electrophoresis tank anode electrode and having the conductive property form a direct current circuit loop.
The mixture of biological macromolecules (DNA or RNA or protein) with different molecular weights, which is in a negative ion state after being processed, is powered by a direct current electric field of an electrophoresis tank, migrates from the cathode end to the anode end of the electrophoresis tank in gel with the function of a molecular sieve, and realizes the separation of the mixed biological macromolecules under the same electrophoresis starting point position and electrophoresis time according to the principle that the larger the molecule is, the larger the migration resistance in the gel is. The common electrophoresis tanks on the market at present are a horizontal electrophoresis device, a vertical electrophoresis device and a tubular electrophoresis device.
With the research of biological magnetism, the biomacromolecule itself is found to have certain magnetic substance characteristics, which shows that the biomacromolecule has biological paramagnetism under certain conditions. Biological paramagnetism has important biological energy and physiological function functions in the process of biological function activities of proteins and enzymes. From this, it can be known that under the action of the magnetic field, the biological macromolecules can realize sequential motion.
Therefore, the technology combination of the electric field and the magnetic field can be applied to the separation of biomacromolecules, and no application is made.
In view of this, further improvements are needed in the existing electrophoretic devices. The patent aims at providing portable quick biomacromolecule magnetoelectric double-acting separation equipment for carrying out technical improvement.
SUMMERY OF THE UTILITY MODEL
The utility model provides a portable quick two effect splitter of biomacromolecule magnetoelectric to prior art's shortcoming, solved the defect of above-mentioned technique.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the portable quick biomacromolecule magnetoelectric double-acting separation equipment comprises a shell, wherein an electrophoresis tank is arranged in the shell; a plate body is arranged in the electrophoresis tank, gel is arranged on the plate body, and the plate body and the gel are divided into a plurality of segmentation areas; the method is characterized in that: the inner surface of the shell is provided with a control box and a magnetic field sub-control box; a power switch and a power relay are arranged in the control box; a magnetic field relay and a tapping line bar are arranged in the magnetic field tapping control box; the two opposite inner surfaces of the shell are provided with movable mounting components, the movable mounting components are provided with electric field generators and magnetic field generators, and the electric field generators and the magnetic field generators correspond to all the segmentation areas.
According to a further optimized technical scheme, the movable mounting assembly comprises two slot plates symmetrically mounted on the inner surface of the shell, and a slot is formed in the inner side surface of each slot plate; a movable mounting plate is inserted between the two slots; the movable mounting plate is provided with an electric field generator and a magnetic field generator.
According to a further optimized technical scheme, the electric field generator comprises a wiring terminal arranged on the movable mounting plate; the wiring terminal is respectively connected with a power supply positive connector and a power supply negative connector which are arranged in the shell; the power supply positive connector and the power supply negative connector are respectively connected with the power supply relay.
According to the further optimized technical scheme, the magnetic field generator comprises a magnetic field relay, a tapping line row and a plurality of magnetic field generating assemblies, and all the magnetic field generating assemblies correspond to all the segmentation areas one to one; the power supply relay is connected with the magnetic field relay, the magnetic field relay is connected with the tapping line bank, and the tapping line bank is connected with the magnetic field generating assembly.
According to a further optimized technical scheme, the magnetic field generating assembly comprises an induction coil and a magnetic field conductor arranged in the induction coil; the induction coil comprises a metal coil, a current regulator and a switch which are connected with the metal coil in series; the switch and the current regulator are respectively connected with the tapping line bank.
According to the further optimized technical scheme, a plurality of spiral fastening devices for fixing the electrophoresis tank are arranged in the shell.
According to a further optimized technical scheme, the spiral fastening device comprises a conical sleeve arranged on the inner wall of the shell, and the conical sleeve is in a three-petal shape or a four-petal shape; a mounting hole is formed in the conical sleeve, and a fastening rod is movably inserted in the mounting hole; the outer surface of the conical sleeve is provided with an external thread, and the external thread is connected with a nut in a threaded manner.
Owing to adopted above-mentioned technique, compare with prior art, the beneficial effects of the utility model are that:
1. the utility model discloses make full use of inner space, movable mounting panel integrated electric field generator and magnetic field generator at first use the mode that electric field and magnetic field combine to use same DC power supply, guarantee the linear motion of macromolecule in biological macromolecule separation process, the condition of skew can not appear, and equipment overall design is reasonable, simple structure, small and exquisite light, conveniently carries and carries, and the in-service use is effectual.
2. The utility model discloses an inside is provided with a anchorage bar, can firmly fix the electrophoresis tank, guarantees that it realizes stably at the removal in-process, can drop into work at once after the installation finishes, has fully demonstrated portable advantage.
Drawings
Fig. 1 is a schematic external structural view of an embodiment of the present invention;
fig. 2 is a schematic view of an overhead internal structure according to an embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.
Example 1
As shown in fig. 1-2, the portable rapid biomacromolecule magnetoelectric double-acting separation device comprises a shell 8, and a cover body 1 can be additionally arranged on the shell 8. The electrophoresis tank 3 is installed in the housing 8. The electrophoresis tank is internally provided with a plate body, the plate body is provided with gel, and the plate body and the gel are divided into a plurality of segmentation areas. The above structures are all the prior art, and the mechanism and the working principle are not described in detail.
The inner surface of the shell 8 is provided with a control box 5 and a magnetic field branch control box 15. And a power switch and a power relay are arranged in the control box 5. And a magnetic field relay and a tapping line bar are arranged in the magnetic field branch control box 15. In addition, the housing is provided with a wiring socket 7 for connecting an external line or for being completed by the following technology.
And movable mounting components are arranged on two opposite inner surfaces of the shell. The movable mounting assembly comprises two slot plates 12 symmetrically mounted on the inner surface of the shell, and a slot is formed in the inner side surface of each slot plate 12. A movable mounting plate 13 is inserted between the two slots, and an electric field generator and a magnetic field generator 14 are mounted on the movable mounting plate 13. The electric field generator and the magnetic field generator correspond to all of the segmented regions. This is because the separation of biological macromolecules using the principle of electrophoresis is carried out under the action of a simple electric field, but occurs at the edge of the electrophoresis chamber and the gel
The electric field generator comprises a wiring terminal arranged on the movable mounting plate; the wiring terminal is respectively connected with a power supply positive connector and a power supply negative connector which are arranged in the shell; the power supply positive connector and the power supply negative connector are respectively connected with the power supply relay.
The magnetic field generator comprises a magnetic field relay, a tapping line row and a plurality of magnetic field generating assemblies, and all the magnetic field generating assemblies correspond to all the segmentation areas one to one; the power supply relay is connected with the magnetic field relay, the magnetic field relay is connected with the tapping line bank, and the tapping line bank is connected with the magnetic field generating assembly. The magnetic field generating assembly comprises an induction coil and a magnetic field conductor arranged in the induction coil; the induction coil comprises a metal coil, a current regulator and a switch which are connected with the metal coil in series; the switch and the current regulator are respectively connected with the tapping line bank.
The inside of the shell is provided with a plurality of spiral fastening devices for fixing the electrophoresis tank. The screw fastening device comprises a conical sleeve 10 arranged on the inner wall of the shell, and the conical sleeve 10 is in a three-lobe shape or a four-lobe shape. The interior of the conical sleeve 10 is provided with a mounting hole, and a fastening rod 11 is movably inserted in the mounting hole. And an external thread is arranged on the outer surface of the conical sleeve 11, and a nut 9 is connected to the external thread in a threaded manner. When the electrophoresis tank is used, the nut 9 is loosened firstly, the fastening rod moves to push the electrophoresis tank tightly, then the nut is screwed, the conical sleeve clamps the fastening rod, and the fastening effect is realized.
In this embodiment, the screw fastening device is made of plastic material or other insulating material, so as to avoid generating other magnetic fields.
The utility model discloses make full use of inner space, movable mounting panel integrated electric field generator and magnetic field generator at first use the mode that electric field and magnetic field combine to use same DC power supply, guarantee the linear motion of macromolecule in biological macromolecule separation process, the condition of skew can not appear, and equipment overall design is reasonable, simple structure, small and exquisite light, conveniently carries and carries, and the in-service use is effectual.
The utility model discloses an inside is provided with a anchorage bar, can firmly fix the electrophoresis tank, guarantees that it realizes stably at the removal in-process, can drop into work at once after the installation finishes, has fully demonstrated portable advantage.
The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.
Claims (7)
1. The portable quick biomacromolecule magnetoelectric double-acting separation equipment comprises a shell, wherein an electrophoresis tank is arranged in the shell; a plate body is arranged in the electrophoresis tank, gel is arranged on the plate body, and the plate body and the gel are divided into a plurality of segmentation areas;
the method is characterized in that:
the inner surface of the shell is provided with a control box and a magnetic field sub-control box; a power switch and a power relay are arranged in the control box; a magnetic field relay and a tapping line bar are arranged in the magnetic field tapping control box;
the two opposite inner surfaces of the shell are provided with movable mounting assemblies, the movable mounting assemblies are provided with electric field generators and magnetic field generators, and the electric field generators and the magnetic field generators correspond to all the segmentation areas.
2. The portable rapid biomacromolecule magnetoelectric double-acting separation device according to claim 1, characterized in that: the movable mounting assembly comprises two slot plates symmetrically mounted on the inner surface of the shell, and a slot is formed in the inner side surface of each slot plate; a movable mounting plate is inserted between the two slots; the movable mounting plate is provided with an electric field generator and a magnetic field generator.
3. The portable rapid biomacromolecule magnetoelectric double-acting separation device according to claim 2, characterized in that: the electric field generator comprises a wiring terminal arranged on the movable mounting plate; the wiring terminal is respectively connected with a power supply positive connector and a power supply negative connector which are arranged in the shell; the power supply positive connector and the power supply negative connector are respectively connected with the power supply relay.
4. A portable rapid biomacromolecule magnetoelectric double-acting separation device according to claim 3, characterized in that: the magnetic field generator comprises a magnetic field relay, a tapping line row and a plurality of magnetic field generating assemblies, and all the magnetic field generating assemblies correspond to all the segmentation areas one to one; the power supply relay is connected with the magnetic field relay, the magnetic field relay is connected with the tapping line bank, and the tapping line bank is connected with the magnetic field generating assembly.
5. A portable rapid biomacromolecule magnetoelectric double-acting separation device according to claim 4, characterized in that: the magnetic field generating assembly comprises an induction coil and a magnetic field conductor arranged in the induction coil; the induction coil comprises a metal coil, a current regulator and a switch which are connected with the metal coil in series; the switch and the current regulator are respectively connected with the tapping line bank.
6. The portable rapid biomacromolecule magnetoelectric double-acting separation device according to claim 1, characterized in that: the inside of the shell is provided with a plurality of spiral fastening devices for fixing the electrophoresis tank.
7. A portable rapid biomacromolecule magnetoelectric double-acting separation device according to claim 6, characterized in that: the spiral fastening device comprises a conical sleeve arranged on the inner wall of the shell, and the conical sleeve is in a three-petal shape or a four-petal shape; a mounting hole is formed in the conical sleeve, and a fastening rod is movably inserted in the mounting hole; the outer surface of the conical sleeve is provided with an external thread, and the external thread is connected with a nut in a threaded manner.
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CN202123299494.2U CN217112169U (en) | 2021-12-24 | 2021-12-24 | Portable quick biomacromolecule magnetoelectric double-acting separation equipment |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN114276409A (en) * | 2021-12-24 | 2022-04-05 | 上海天能生命科学有限公司 | Electromagnetic composite biomacromolecule separation technology and equipment |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN114276409A (en) * | 2021-12-24 | 2022-04-05 | 上海天能生命科学有限公司 | Electromagnetic composite biomacromolecule separation technology and equipment |
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