CN217092466U

CN217092466U - Mannan peptide enrichment facility

Info

Publication number: CN217092466U
Application number: CN202220888148.3U
Authority: CN
Inventors: 王峰; 路超刚; 张牛; 孟燕
Original assignee: Henan Quanyu Pharmaceutical Co ltd
Current assignee: Henan Quanyu Pharmaceutical Co ltd
Priority date: 2022-04-18
Filing date: 2022-04-18
Publication date: 2022-08-02
Anticipated expiration: 2032-04-18

Abstract

The utility model discloses a mannatide enrichment facility belongs to the concentrated technical field of mannatide, and the mode that aims at solving present concentrated mannatide solution is single, and concentration efficiency and effect are not good, can't carry out prefilter edulcoration and concentration to solution, has the problem of calorific loss and the extravagant condition of water resource. Through the arrangement of the first filter screen, the primary filtering concentration layer, the electromagnetic valve, the stirring device and the resistance heater, the mannatide solution can be sequentially subjected to primary filtering, impurity removal, water absorption concentration and sealing heating concentration, and meanwhile, the solution is uniformly stirred so as to be uniformly heated, and various concentration modes are used, so that the concentration efficiency and effect are improved; through the setting of condenser pipe, heat transfer device, moisture meter, temperature sensor and baroceptor, can carry out the condensation heat transfer to exhaust steam, reduce calorific loss, avoid the waste of water resource, atmospheric pressure and mannan peptide solution's in the while can real-time supervision concentrated jar temperature, moisture content.

Description

Mannan peptide enrichment facility

Technical Field

The utility model relates to a mannatide concentration technical field specifically is a mannatide enrichment facility.

Background

Mannan peptide is white or yellowish amorphous powder, is odorless and tasteless, is easily soluble in water, is insoluble in organic solvents, is a mixture with stable chemical properties and certain uniformity, does not contain micromolecular saccharides such as monosaccharide and disaccharide and free amino acid, is completely composed of mannan peptide molecules with different chain lengths, and has the molecular mass of about 71 ku. The content of total sugar in the mannatide is 87.7-90.3%, and the mannatide mainly contains mannose and a small amount of glucose residues; the total content of amino acids is 4.5% -6.2%, mainly including aspartic acid, threonine, serine, glutamic acid, alanine and leucine, wherein the sugar chain and the peptide chain are connected by N-glycosidic bond connection and O-glycosidic bond connection. The mannan peptide tablet can inhibit the synthesis of DNA and RNA of cell strains such as S-180 sarcoma, Ehrlich ascites carcinoma, human tongue squamous cell carcinoma Tca8113 and the like and glucose metabolism in vitro of animals; can inhibit the growth of Ehrlich ascites carcinoma, S-180 sarcoma and HePA liver cancer ascites tumor (tumor inhibition rate is 63%), can promote peripheral leukocyte, enhance phagocytic function of reticuloendothelial system, activate macrophage and lymphocyte, induce thymic lymphocyte to generate active substance, improve and enhance organism immunity and stress capability; has effects in activating phagocyte, NK cell, and T.B cell subset; has the functions of inducing interferon and interleukin, etc.

When preparing mannatide, need carry out concentrated processing to the mannatide solution of extracting, current concentration method is mostly directly to heat and boil the concentration, and the concentration mode is single, and concentration efficiency and effect are not good, can't carry out prefilter edulcoration and concentration to mannatide solution, and the steam that the direct heating boiled the production can directly discharge in the air moreover, has calorific loss and the extravagant condition of water resource.

SUMMERY OF THE UTILITY MODEL

In view of the problems in the prior art, the utility model discloses a mannan peptide concentration device, which adopts the technical proposal that the mannan peptide concentration device comprises a storage tank, a concentration tank, a water storage tank and a microprocessor, the storage tank, the concentration tank and the water storage tank are sequentially arranged from left to right, the microprocessor is arranged inside the concentration tank, a first filter screen is arranged at the inlet of the storage tank, a primary filter concentration layer is arranged inside the storage tank, the mannan peptide solution added into the storage tank can be preliminarily filtered, decontaminated and concentrated by the arrangement of the first filter screen and the primary filter concentration layer, one side of the concentration tank is provided with an inlet pipe, the other side of the concentration tank is provided with an exhaust pipe, the bottom of the concentration tank is provided with a discharge pipe, and the mannan peptide solution can be conveniently fed and discharged through the arrangement of the inlet pipe, the exhaust pipe and the discharge pipe, the feeding pipe, the exhaust pipe and the discharging pipe are all provided with electromagnetic valves, the electromagnetic valves can control the opening and closing of the feeding pipe, the exhaust pipe and the discharging pipe, the storage tank is communicated with the feeding pipe through the conveying device, mannatide solution in the storage tank can be guided into the concentration tank through the arrangement of the conveying device, the stirring device is arranged in the concentration tank, the mannatide solution can be uniformly stirred through the arrangement of the stirring device, the mannatide solution is uniformly heated, the concentration efficiency and the concentration effect are improved, the inner wall of the concentration tank is provided with the resistance heater, the mannatide solution can be heated and concentrated through the arrangement of the resistance heater, the front of the concentration tank is provided with the sealing cover, the sealing of the concentration tank can be kept when the concentration tank is closed, and the concentrated interior of the tank can be conveniently cleaned when the concentration tank is opened, the controller is arranged below the sealing cover, the whole concentration process can be manually controlled by using the controller, one side of the discharge pipe is connected with the condenser pipe, the condenser pipe is communicated with the water storage tank through the heat exchange device, the discharged steam can be condensed and heat exchanged through the arrangement of the condenser pipe and the heat exchange device, the heat loss is reduced, the waste of water resources is avoided, the condensed water is guided into the water storage tank, the bottom of the condenser pipe is communicated with the water storage tank, the top of the condenser pipe is provided with an exhaust port, the air pressure in the concentration tank can be conveniently balanced through the arrangement of the exhaust port, the second filter screen is arranged in the exhaust port, foreign matters can be prevented from falling into the water storage tank through the arrangement of the second filter screen, a water outlet is arranged on one side of the water storage tank, and the water in the water storage tank can be conveniently discharged through the arrangement of the water outlet, the inside of concentrated jar is provided with moisture meter, temperature sensor and baroceptor, through moisture meter, temperature sensor and baroceptor's setting, can the atmospheric pressure in the real-time supervision concentrated jar and the temperature of mannan peptide solution, moisture content, solenoid valve, conveyor, agitating unit, resistance heater, controller, heat transfer device, moisture meter, temperature sensor and baroceptor all are connected with microprocessor.

As an optimal technical scheme of the utility model, elementary filtration concentration layer includes ultrafiltration rete, calcium chloride adsorbed layer and silica gel adsorbed layer, ultrafiltration rete, calcium chloride adsorbed layer and silica gel adsorbed layer set gradually under to in the inside of holding vessel from the top down, through the setting of ultrafiltration rete, calcium chloride adsorbed layer and silica gel adsorbed layer, can filter edulcoration and the concentration of absorbing water in proper order to mannatide solution.

As an optimal technical scheme of the utility model, conveyor includes conveyer pipe and first delivery pump, through conveyer pipe and first delivery pump intercommunication between holding vessel and the inlet pipe, first delivery pump sets up in one side of holding vessel, the entrance point of conveyer pipe is located the inner diapire of holding vessel, first delivery pump is connected with microprocessor, through the setting of conveyer pipe and first delivery pump, can be with the leading-in concentrated jar of mannatide solution in the holding vessel in.

As an optimal technical scheme of the utility model, agitating unit includes agitator motor, pivot and stirring leaf, the top of concentrated jar is provided with agitator motor, agitator motor's output is located the internal hub connection of concentrated jar and has the pivot, the outside fixedly connected with stirring leaf of pivot, agitator motor is connected with microprocessor, through agitator motor, pivot and stirring leaf's setting, can realize the even stirring to mannan peptide solution, makes it be heated evenly, improves concentrated efficiency and effect.

As the utility model discloses an optimal technical scheme, the front of holding vessel, sealed lid and storage water tank all is provided with the observation window, through the setting of observation window, can conveniently look over the condition in holding vessel, concentrated jar and the storage water tank.

As the utility model discloses a preferred technical scheme, heat transfer device includes heat exchange tube, second delivery pump and back flow, the inside intercommunication of heat exchange tube and storage water tank is passed through to the bottom of condenser pipe one side, the one end setting that the inner bottom wall of storage water tank is located the heat exchange tube is connected with the second delivery pump, the inside intercommunication of back flow and storage water tank is passed through to the bottom of condenser pipe opposite side, the second delivery pump is connected with microprocessor, through the setting of heat exchange tube, second delivery pump and back flow, can be with the leading-in condenser pipe of hydrologic cycle in the storage water tank, improve condensation effect.

As the utility model discloses a preferred technical scheme, the equal fixedly connected with landing leg in bottom of holding vessel, concentrated jar and storage water tank, through the setting of landing leg, can the stable stay holding vessel, concentrated jar and storage water tank.

The utility model has the advantages that: the utility model discloses a first filter screen, the concentrated layer of elementary filtration, a solenoid valve, agitating unit and resistance heater's cooperation setting, first filter screen and the concentrated layer of elementary filtration can carry out prefiltration edulcoration and concentration to the mannatide solution that adds in the holding vessel, the inlet pipe can be closed to the solenoid valve, blast pipe and row's material pipe, sealed in the concentrated jar when guaranteeing to concentrate, resistance heater can heat the mannatide solution and concentrate, agitating unit evenly stirs mannatide solution, make it be heated evenly, multiple concentration mode has been used, concentration efficiency and effect have been improved; through the condenser pipe, heat transfer device, the moisture meter, temperature sensor and baroceptor's cooperation sets up, the condenser pipe can carry out the condensation heat transfer to exhaust steam, reduce calorific loss, avoid the waste of water resource, and with the leading-in storage water tank of moisture after the condensation, heat transfer device can be with the leading-in condenser pipe of the hydrologic cycle in the storage water tank, improve condensation effect, simultaneously the moisture meter, temperature sensor and baroceptor can the temperature of atmospheric pressure and mannan peptide solution in the real-time supervision concentrated jar, the moisture content.

Drawings

FIG. 1 is a schematic view of the structure of the present invention;

FIG. 2 is a schematic view of the cross-sectional structure of the present invention;

fig. 3 is an enlarged schematic view of the a position of the present invention.

In the figure: 1. a storage tank; 2. a concentration tank; 3. a water storage tank; 4. a first filter screen; 5. a primary filtration concentration layer; 501. an ultrafiltration membrane layer; 502. a calcium chloride adsorption layer; 503. a silica gel adsorption layer; 6. a feed pipe; 7. an exhaust pipe; 8. a discharge pipe; 9. an electromagnetic valve; 10. a conveying device; 1001. a delivery pipe; 1002. a first delivery pump; 11. a stirring device; 1101. a stirring motor; 1102. a rotating shaft; 1103. stirring blades; 12. a resistance heater; 13. a sealing cover; 14. a controller; 15. a condenser tube; 16. a heat exchange device; 1601. a heat exchange pipe; 1602. a second delivery pump; 1603. a return pipe; 17. an exhaust port; 18. a second filter screen; 19. a water outlet; 20. an observation window; 21. and (7) supporting legs.

Detailed Description

Example 1

The technical solution of the present invention will be clearly and completely described with reference to the accompanying drawings. In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance. In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

As shown in fig. 1 to 3, the utility model discloses a mannan peptide concentrating device, which adopts the technical proposal that the mannan peptide concentrating device comprises a storage tank 1, a concentrating tank 2, a water storage tank 3 and a microprocessor, wherein the storage tank 1, the concentrating tank 2 and the water storage tank 3 are sequentially arranged from left to right, the microprocessor is arranged inside the concentrating tank 2, a first filter screen 4 is arranged at the inlet of the storage tank 1, a primary filtering and concentrating layer 5 is arranged inside the storage tank 1, mannan peptide solution added into the storage tank 1 is sequentially primarily filtered and concentrated by the first filter screen 4 and the primary filtering and concentrating layer 5, one side of the concentrating tank 2 is provided with an inlet pipe 6, the other side of the concentrating tank 2 is provided with an exhaust pipe 7, the bottom of the concentrating tank 2 is provided with a discharge pipe 8, and the inlet pipe 6, the exhaust pipe 7 and the discharge pipe 8 are all provided with an electromagnetic valve 9, the inlet pipe 6, the exhaust pipe 7 and the discharge pipe 8 can be opened and closed by using the electromagnetic valve 9, the storage tank 1 is communicated with the inlet pipe 6 through the conveying device 10, the solution in the storage tank 1 is guided into the concentration tank 2 from the inlet pipe 6 by the conveying device 10, the stirring device 11 is arranged in the concentration tank 2, the inner wall of the concentration tank 2 is provided with the resistance heater 12, the resistance heater 12 heats and concentrates the solution, the stirring device 11 uniformly stirs the solution, the solution is uniformly heated, the concentration efficiency and the concentration effect are improved, the front surface of the concentration tank 2 is provided with the sealing cover 13, the sealing cover 13 is convenient for cleaning the inside of the concentration tank 2 in the later period, the controller 14 is arranged below the sealing cover 13, the controller 14 is used for conveniently checking the temperature, the air pressure and the water content of the solution in the concentration tank 2, and the whole concentration process can be manually controlled simultaneously, arrange one side of material pipe 8 and be connected with condenser pipe 15, condenser pipe 15 condenses blast pipe 7 exhaust steam, condenser pipe 15 passes through heat transfer device 16 and storage water tank 3 intercommunication, and heat transfer device 16 is with leading-in condenser pipe 15 of the hydrologic cycle in the storage water tank 3, the bottom and the storage water tank 3 intercommunication of condenser pipe 15, the top of condenser pipe 15 is provided with gas vent 17, and remaining gas is discharged from gas vent 17 after the condensation, the inside of gas vent 17 is provided with second filter screen 18, and second filter screen 18 prevents that external foreign matter from falling into storage water tank 3, one side of storage water tank 3 is provided with outlet 19, and outlet 19 can in time discharge the water in the storage water tank 3, the inside of concentrated jar 2 is provided with moisture meter, temperature sensor and baroceptor, and moisture meter, temperature sensor and baroceptor can real-time monitoring the temperature in the concentrated jar 2, The electromagnetic valve 9, the conveying device 10, the stirring device 11, the resistance heater 12, the controller 14, the heat exchange device 16, the moisture meter, the temperature sensor and the air pressure sensor are all connected with the microprocessor.

As an optimal technical scheme of the utility model, elementary filtration concentrated layer 5 includes ultrafiltration rete 501, calcium chloride adsorbed layer 502 and silica gel adsorbed layer 503, ultrafiltration rete 501, calcium chloride adsorbed layer 502 and silica gel adsorbed layer 503 set gradually in the inside from the top down of holding vessel 1, and ultrafiltration rete 501, calcium chloride adsorbed layer 502 and silica gel adsorbed layer 503 filter solution and the concentration of absorbing water in proper order.

As an optimal technical scheme of the utility model, conveyor 10 includes conveyer pipe 1001 and first delivery pump 1002, communicate through conveyer pipe 1001 and first delivery pump 1002 between holding vessel 1 and the inlet pipe 6, first delivery pump 1002 sets up in one side of holding vessel 1, the entrance point of conveyer pipe 1001 is located the inner diapire of holding vessel 1, first delivery pump 1002 is connected with microprocessor, opens first delivery pump 1002 back, can follow the leading-in concentrated jar 2 of conveyer pipe 1001 with the solution in the holding vessel 1.

As an optimal technical scheme of the utility model, agitating unit 11 includes agitator motor 1101, pivot 1102 and stirring leaf 1103, the top of concentrated jar 2 is provided with agitator motor 1101, agitator motor 1101's output is located the internal shaft of concentrated jar 2 and is connected with pivot 1102, the outside fixedly connected with stirring leaf 1103 of pivot 1102, agitator motor 1101 is connected with microprocessor, opens behind agitator motor 1101, and pivot 1102 drives stirring leaf 1103 and rotates to carry out the homogeneous stirring to solution, make it be heated evenly, improve concentrated efficiency and effect.

As an optimal technical scheme of the utility model, the front of holding vessel 1, sealed lid 13 and storage water tank 3 all is provided with observation window 20, sees through observation window 20 and can look over the condition in holding vessel 1, concentrated jar 2 and the storage water tank 3.

As an optimal technical scheme of the utility model, heat transfer device 16 includes heat exchange tube 1601, second delivery pump 1602 and back flow 1603, the inside intercommunication of heat exchange tube 1601 and storage water tank 3 is passed through to the bottom of condenser pipe 15 one side, the one end setting that the inner bottom wall of storage water tank 3 is located heat exchange tube 1601 is connected with second delivery pump 1602, the inside intercommunication of back flow 1603 and storage water tank 3 is passed through to the bottom of condenser pipe 15 opposite side, second delivery pump 1602 is connected with microprocessor, opens after second delivery pump 1602, and water in the storage water tank 3 is from heat exchange tube 1601 suction condenser pipe 15, water after the heat transfer and follow back flow 1603 and flow back into storage water tank 3.

As an optimal technical scheme of the utility model, the equal fixedly connected with landing leg 21 in bottom of holding vessel 1, concentrated jar 2 and storage water tank 3, landing leg 21 makes holding vessel 1, concentrated jar 2 and storage water tank 3 remain stable.

The utility model discloses a theory of operation: when concentrating the mannatide solution, firstly adding the solution into a storage tank 1, sequentially filtering and concentrating the solution by a first filter screen 4, an ultrafiltration membrane layer 501, a calcium chloride adsorption layer 502 and a silica gel adsorption layer 503, then starting a first delivery pump 1002 by a controller 14, guiding the solution in the storage tank 1 into a concentration tank 2 from a delivery pipe 1001 and a feed pipe 6, then closing the feed pipe 6, an exhaust pipe 7 and a discharge pipe 8 by an electromagnetic valve 9, keeping the interior of the concentration tank 2 sealed, then starting a resistance heater 12 and a stirring motor 1101, heating and concentrating the solution by the resistance heater 12, simultaneously driving a stirring blade 1103 to rotate by a rotating shaft 1102, thereby uniformly stirring the solution, uniformly heating the solution, improving the concentration efficiency and effect, monitoring the temperature, the air pressure and the water content of the solution in the concentration tank 2 in real time by a moisture meter, a temperature sensor and a pressure sensor, the temperature in the concentrate jar 2, the moisture content data of atmospheric pressure and solution are through the demonstration of controller 14, when reaching maximum atmospheric pressure in the concentrate jar 2, in time open blast pipe 7 exhaust steam, exhaust steam is condensed by condenser pipe 15, open second delivery pump 1602 after that, water from heat exchange tube 1601 suction condenser pipe 15 in with storage water tank 3, water after the heat transfer flows back into storage water tank 3 from back flow 1603, water after the condensation also flows into storage water tank 3, remaining gas is discharged from gas vent 17, second filter screen 18 prevents that external foreign matter from falling into storage water tank 3, can look over storage tank 1 through observation window 20, the condition and the liquid level in concentrate jar 2 and the storage water tank 3, water in the storage water tank 3 can in time be discharged from outlet 19.

The microprocessor adopts an STM32 chip for controlling the switches of the motor, the pump and the resistance heater and transmitting signals, and the technical advices can be obtained by those skilled in the art by referring to textbooks or technical manuals published by manufacturers by the pins and the connection mode of the STM 32; the circuit and mechanical connections of the present invention are conventional means used by those skilled in the art, and can be suggested by limited tests, which are common knowledge.

Components not described in detail herein are prior art.

Although the present invention has been described in detail with reference to the specific embodiments, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge range of those skilled in the art, and modifications or variations without creative efforts are still within the scope of the present invention.

Claims

1. The utility model provides a mannan peptide enrichment facility, includes holding vessel (1), concentrated jar (2), storage water tank (3) and microprocessor, holding vessel (1), concentrated jar (2) and storage water tank (3) set gradually from left to right, the inside of concentrated jar (2) is provided with microprocessor, its characterized in that: the filter screen is characterized in that a first filter screen (4) is arranged at an inlet of the storage tank (1), a primary filtering concentration layer (5) is arranged inside the storage tank (1), an inlet pipe (6) is arranged on one side of the concentration tank (2), an exhaust pipe (7) is arranged on the other side of the concentration tank (2), a discharge pipe (8) is arranged at the bottom of the concentration tank (2), electromagnetic valves (9) are arranged at the inlet pipe (6), the exhaust pipe (7) and the discharge pipe (8), the storage tank (1) is communicated with the inlet pipe (6) through a conveying device (10), a stirring device (11) is arranged inside the concentration tank (2), a resistance heater (12) is arranged on the inner wall of the concentration tank (2), a sealing cover (13) is arranged on the front side of the concentration tank (2), and a controller (14) is arranged below the sealing cover (13), one side of arranging material pipe (8) is connected with condenser pipe (15), condenser pipe (15) are through heat transfer device (16) and storage water tank (3) intercommunication, the bottom and storage water tank (3) intercommunication of condenser pipe (15), the top of condenser pipe (15) is provided with gas vent (17), the inside of gas vent (17) is provided with second filter screen (18), one side of storage water tank (3) is provided with outlet (19), the inside of concentrate jar (2) is provided with moisture meter, temperature sensor and baroceptor, solenoid valve (9), conveyor (10), agitating unit (11), resistance heater (12), controller (14), heat transfer device (16), moisture meter, temperature sensor and baroceptor all are connected with microprocessor.

2. The mannan peptide concentrating device according to claim 1, wherein: elementary filtration concentrated layer (5) are including ultrafiltration rete (501), calcium chloride adsorbed layer (502) and silica gel adsorbed layer (503), ultrafiltration rete (501), calcium chloride adsorbed layer (502) and silica gel adsorbed layer (503) set gradually under the inside from the top down of holding vessel (1).

3. The mannan peptide concentrating device according to claim 1, wherein: conveyor (10) are including conveyer pipe (1001) and first delivery pump (1002), communicate through conveyer pipe (1001) and first delivery pump (1002) between holding vessel (1) and inlet pipe (6), first delivery pump (1002) set up in one side of holding vessel (1), the entrance point of conveyer pipe (1001) is located the interior diapire of holding vessel (1), first delivery pump (1002) are connected with microprocessor.

4. The mannan peptide concentrating device according to claim 1, wherein: agitating unit (11) are including agitator motor (1101), pivot (1102) and stirring leaf (1103), the top of concentrated jar (2) is provided with agitator motor (1101), the output of agitator motor (1101) is located the internal shaft of concentrated jar (2) and is connected with pivot (1102), the outside fixedly connected with stirring leaf (1103) of pivot (1102), agitator motor (1101) is connected with microprocessor.

5. The mannan peptide concentrating device according to claim 1, wherein: the front surfaces of the storage tank (1), the sealing cover (13) and the water storage tank (3) are all provided with observation windows (20).

6. The mannan peptide concentrating device according to claim 1, wherein: heat transfer device (16) include heat exchange tube (1601), second delivery pump (1602) and back flow (1603), the inside intercommunication of heat exchange tube (1601) and storage water tank (3) is passed through to the bottom of condenser pipe (15) one side, the one end setting that the interior diapire of storage water tank (3) is located heat exchange tube (1601) is connected with second delivery pump (1602), the inside intercommunication of back flow (1603) and storage water tank (3) is passed through to the bottom of condenser pipe (15) opposite side, second delivery pump (1602) is connected with microprocessor.

7. The mannan peptide concentrating device according to claim 1, wherein: the bottom of the storage tank (1), the bottom of the concentration tank (2) and the bottom of the water storage tank (3) are fixedly connected with supporting legs (21).