CN217033306U - Stepped configuration device for different solution concentrations based on high-flux microfluidics - Google Patents
Stepped configuration device for different solution concentrations based on high-flux microfluidics Download PDFInfo
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Abstract
The utility model discloses a stepped configuration device for different solution concentrations based on high-throughput microfluidics, which comprises: the solution distribution device comprises m solution distribution mechanisms which are sequentially arranged along the gravity direction, each solution distribution mechanism comprises n solution pools which are isolated from each other, two adjacent solution distribution mechanisms in the m solution distribution mechanisms are defined as a first solution distribution mechanism and a second solution distribution mechanism, each solution pool in the first solution distribution mechanism is also communicated with at least two selected solution pools in the second solution distribution mechanism, and the solution in one solution pool in the first solution distribution mechanism can automatically flow into the at least two selected solution pools in the second solution distribution mechanism under the action of gravity. The stepped configuration device provided by the embodiment of the utility model can output sample solutions with various target concentrations at the same time, and the configuration efficiency of solutions with different concentration gradients is obviously improved.
Description
Technical Field
The utility model particularly relates to a high-throughput micro-fluidic based stepped configuration device with different solution concentrations, and belongs to the technical field of material preparation.
Background
With the development of industry, the problem of water pollution is also becoming more severe. The sewage treatment and the standard discharge are indispensable. A large amount of indexes are required to be detected in sewage treatment and standard discharge, wherein the sewage is detected by using a traditional method and is widely applied to industries and laboratories. However, the detection process by the conventional means is slow, because the conventional means is mostly based on 'case-by-case public customs' and scattered 'experimental trial and error'. In the future, sewage detection and standard discharge must be established on the basis of a huge basic database, high-throughput test and automatic control, so that for sewage with different concentration gradients, improvement on the configuration mode is urgently needed, and the mechanism of influence of process parameters such as sewage concentration, sewage flow rate and the like on the configured sewage concentration gradient is explored. How to obtain single batch large-scale experimental data of multi-concentration gradient sewage is a key problem for solving a high-throughput microfluidic research and development mode. The micro-fluidic and high-throughput technology are combined with each other, so that the solution can be accurately and dynamically controlled and configured in a large scale, the solution in the system can be dynamically updated, and the system is particularly suitable for sewage detection; on the other hand, the method can accurately control solution diffusion, create a gradient solution concentration field, and is suitable for solution preparation with different concentration gradients.
At present, related patents can perform batch preparation on solutions with the same concentration, for example, chinese patent CN105107557A, which greatly improves the preparation efficiency of solutions from one to n, and such high-throughput solution preparation methods adopt a matrix solution sample preparation device 3-9-27 … … (even larger scale), which greatly improves the efficiency of solution batch preparation, but the device can only perform batch preparation on solutions with a single concentration, when solutions with multiple concentrations need to be prepared, only the batch preparation of a single solution can be performed according to the above patents, a large amount of time is required for preparing sample solutions with different concentrations, the detection efficiency will decrease with the increase of the sample concentration gradient, and the preparation efficiency of the large-scale solution concentration gradient still needs to be improved.
SUMMERY OF THE UTILITY MODEL
The utility model mainly aims to provide a stepped configuration device based on high-throughput microfluidics and different solution concentrations, so that the defects in the prior art are overcome.
In order to achieve the purpose of the utility model, the technical scheme adopted by the utility model comprises the following steps:
the embodiment of the utility model provides a stepped configuration device based on high-throughput microfluidics and different solution concentrations, which comprises: m solution allocation mechanisms are sequentially arranged along the gravity direction, each solution allocation mechanism comprises n solution pools which are isolated from each other,
defining any two adjacent solution allocation mechanisms in the m solution allocation mechanisms as a first solution allocation mechanism and a second solution allocation mechanism, wherein the first solution allocation mechanism is positioned above the second solution allocation mechanism, each solution pool in the first solution allocation mechanism is also communicated with at least two selected solution pools in the second solution allocation mechanism, and the solution in one solution pool in the first solution allocation mechanism can automatically flow into at least two selected solution pools in the second solution allocation mechanism under the action of gravity; and (c) a second step of,
the solution tank contained in the solution configuration mechanism positioned at the topmost layer is also provided with a solution inlet, and the solution tank contained in the solution configuration mechanism positioned at the bottommost layer is also connected with a second liquid outlet pipe, wherein m is more than or equal to 2, and n is more than or equal to 2.
Compared with the prior art, the utility model has the advantages that:
the stepped configuration device based on high-flux microfluidics and different solution concentrations, provided by the embodiment of the utility model, has a simple structure and is more convenient to use, the stepped configuration device can realize simultaneous addition of multiple solutions in a short time, and sample solutions with multiple target concentrations are output at the same time, so that the configuration efficiency of solutions with different concentration gradients is remarkably improved;
according to the stepped configuration device based on high-throughput microfluidics and provided by the embodiment of the utility model, under the condition that the target concentration gradient required by the sample solution is determined, the sample solution of a single main system is input through the stepped solution mixing and shunting device, the solution of a single concentration is configured in the solution configuration system, the sample solution of the main system is driven to flow by means of gravitational potential energy, multi-channel output of the solutions of different concentrations in a single preparation batch is finally realized, and the configuration efficiency of the solutions of different concentrations is improved.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments described in the present application, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a schematic diagram of a high throughput microfluidic based stepped configuration of devices with different solution concentrations according to an exemplary embodiment of the present invention;
fig. 2 is an isometric view of a high throughput microfluidic based stepped configuration device of different solution concentrations provided in an exemplary embodiment of the utility model;
FIG. 3 is a top view of a high throughput microfluidic based stepped configuration device of different solution concentrations provided in an exemplary embodiment of the present invention;
FIG. 4 is a front view of a stepped configuration of devices for varying solution concentrations based on high throughput microfluidics, provided in an exemplary embodiment of the present invention;
FIG. 5 is an isometric view of a stepped configuration device for varying solution concentrations based on high throughput microfluidics, provided in an exemplary embodiment of the present invention;
FIG. 6 is a top view of a stepped configuration of devices for varying solution concentrations based on high throughput microfluidics, provided in an exemplary embodiment of the utility model;
FIG. 7 is a graph of five fitted Atrazine (ATZ) solutions of different concentrations provided in an exemplary embodiment of the utility model;
FIG. 8 is a curve fit to five Sulfamethoxazole (SMX) solutions of different concentrations provided in an exemplary embodiment of the present invention;
FIG. 9 is a fitted curve of five Ciprofloxacin (CIP) solutions of different concentrations provided in an exemplary embodiment of the present invention;
FIG. 10 is a plot of a fit of five sodium chloride (NaCl) solutions of different concentrations provided in an exemplary embodiment of the utility model;
FIG. 11 shows five different concentrations of sodium sulfate (Na) provided in an exemplary embodiment of the utility model2SO4) Fitted curve of solution.
Detailed Description
In view of the defects in the prior art, the inventor of the present invention has made extensive research and practice to propose the technical solution of the present invention. The technical solution, its implementation and principles, etc. will be further explained as follows.
The embodiment of the utility model provides a high-throughput microfluidic-based stepped configuration device for different solution concentrations, which can realize simultaneous addition of multiple solution concentration gradients in a short time, output sample solutions with multiple target concentrations at the same time, and remarkably improve the configuration efficiency of solutions with different concentration gradients.
The embodiment of the utility model provides a stepped configuration device based on high-throughput microfluidics and different solution concentrations, which comprises: m solution allocation mechanisms which are sequentially arranged along the gravity direction, each solution allocation mechanism comprises n solution pools which are isolated from each other,
defining any two adjacent solution configuration mechanisms in the m solution configuration mechanisms as a first solution configuration mechanism and a second solution configuration mechanism, wherein the first solution configuration mechanism is positioned above the second solution configuration mechanism, each solution pool in the first solution configuration mechanism is also communicated with at least two selected solution pools in the second solution configuration mechanism, and the solution in one solution pool in the first solution configuration mechanism can automatically flow into at least two selected solution pools in the second solution configuration mechanism under the action of gravity; and the number of the first and second groups,
the solution tank contained in the solution configuration mechanism positioned at the topmost layer is also provided with a solution inlet, and the solution tank contained in the solution configuration mechanism positioned at the bottommost layer is also connected with a second liquid outlet pipe, wherein m is more than or equal to 2, and n is more than or equal to 2.
In a specific embodiment, the solution pools in the first solution distribution mechanism and the second solution distribution mechanism are connected through a flow dividing pipe, the flow dividing pipe includes a liquid inlet pipe and at least two first liquid outlet pipes, the liquid inlet pipe is communicated with the solution pools in the first solution distribution mechanism, one end of each of the at least two first liquid outlet pipes is communicated with the liquid inlet pipe, and the other end of each of the at least two first liquid outlet pipes is in one-to-one correspondence with and communicated with at least two solution pools in the second solution distribution mechanism.
In a specific embodiment, the lengths and pipe diameters of at least two of the first liquid outlet pipes are the same.
In a specific embodiment, the first liquid outlet pipe is further provided with a first adjusting valve, and the second liquid outlet pipe is further provided with a first adjusting valve.
In one embodiment, the number of solution pools included in any two solution distribution mechanisms is the same or different.
In one embodiment, the number of the solution pools included in the m solution disposing mechanisms increases from top to bottom in the gravity direction, and n is m + 1.
In one embodiment, each of the solution reservoirs is closed.
In one embodiment, the m solution disposing mechanisms are further sequentially staggered in the horizontal direction, so that the m solution disposing mechanisms are in a step-like structure as a whole.
In one embodiment, the step configuration apparatus further comprises: the shell is internally provided with a closed cavity, the m solution configuration mechanisms are arranged in the closed cavity, and at least the pipe orifice part of the second liquid outlet pipe is exposed and arranged outside the closed cavity; and/or the housing is formed by connecting transparent support plates.
In a specific embodiment, the closed chamber is further provided with a plurality of partition plates, and the solution distribution mechanism is fixedly arranged on the partition plates.
In a specific embodiment, the plurality of partition plates are sequentially arranged at intervals along the gravity direction, and are sequentially staggered along the horizontal direction, so that the plurality of partition plates are integrally in a step-shaped structure.
The technical solution, implementation processes, principles, and the like will be further explained with reference to the drawings and specific embodiments, and unless otherwise specified, the embodiments of the present invention mainly explain and describe the structure and composition of a step configuration device based on high throughput microfluidics with different solution concentrations, and the size, material, and the like of each solution configuration mechanism in the embodiments of the present invention may be known to those skilled in the art, and are not limited specifically herein.
The technical solution of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. It should be apparent that the described embodiments are only some embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-6, a high throughput microfluidics based stepped configuration device for different solution concentrations includes: the device comprises a shell 100 and m solution configuration mechanisms 200, wherein a closed cavity is arranged in the shell 100, the m solution configuration mechanisms 200 are arranged in the closed cavity, the m solution configuration mechanisms 200 are sequentially arranged along the gravity direction, each solution configuration mechanism 200 comprises n solution pools 201 which are isolated from each other, the solution pool contained in one of the m solution configuration mechanisms 200 which is oppositely arranged at the upper layer along the gravity direction can be communicated with at least two solution pools contained in the other one which is oppositely arranged at the lower layer, the m is more than or equal to 2, and the n is more than or equal to 2.
In this embodiment, any two adjacent solution allocation mechanisms in the m solution allocation mechanisms are defined as a first solution allocation mechanism and a second solution allocation mechanism, the first solution allocation mechanism is located above the second solution allocation mechanism, each solution pool in the first solution allocation mechanism is further communicated with at least two selected solution pools in the second solution allocation mechanism, and a solution in a solution pool in the first solution allocation mechanism can automatically flow into at least two selected solution pools in the second solution allocation mechanism under the action of gravity; and the solution pool contained in the solution configuration mechanism 200 positioned at the bottommost layer is also provided with a solution inlet, the solution pool contained in the solution configuration mechanism 200 positioned at the bottommost layer is also connected with a second liquid outlet pipe 400, and at least the pipe orifice part of the second liquid outlet pipe is exposed and arranged outside the closed chamber.
In this embodiment, each solution pool 201 has a solution inlet and a solution outlet, the solution inlet is correspondingly disposed at the top of the solution pool, and the solution outlet is correspondingly disposed at the bottom of the solution pool, so that the solution can be automatically distributed from top to bottom under the action of gravity.
In this embodiment, a main solution inlet 202 is formed at the top of the solution tank of the topmost solution distribution mechanism, so as to conveniently inject the solution stock solution into the solution tank of the topmost solution distribution mechanism through the main solution inlet.
In this embodiment, the solution pools in two adjacent solution configuration mechanisms are connected via a shunt tube 300, a tube opening at an inlet end of the shunt tube 300 is correspondingly connected with a solution outlet of the solution pool, and a tube opening at an outlet end of the shunt tube 300 is correspondingly connected with a solution inlet of the solution pool.
In this embodiment, each solution pool in the upper solution configuration mechanism of the two adjacent solution configuration mechanisms is connected to a shunt tube, the shunt tube includes a liquid inlet tube and at least two first liquid outlet tubes, the liquid inlet tube is communicated with the solution pool in one of the two solution configuration mechanisms, the at least two first liquid outlet tubes have one end communicated with the liquid inlet tube, and the other end communicated with the at least two solution pools in the other of the two solution configuration mechanisms.
In this embodiment, the shunt tube has two first outlet conduits, it being understood that the shunt tube has an inlet end and two outlet ends, the two outlet ends corresponding to two adjacent wells of the solution distribution structure located in an opposite direction, it being understood that the solution in each well is delivered along the shunt tube to two adjacent wells of the solution distribution structure in the opposite direction.
In this embodiment, the lengths and pipe diameters of the two first liquid outlet pipes are the same, so that the solution in one solution pool can be uniformly distributed into the two solution pools in the lower solution configuration mechanism.
In this embodiment, a first regulating valve is further disposed on the first liquid outlet pipe, a first regulating valve is further disposed on the second liquid outlet pipe, wherein the first regulating valve disposed on the first liquid outlet pipe is used for regulating a flow rate of the solution output from the first liquid outlet pipe, a second regulating valve disposed on the second liquid outlet pipe is used for regulating a flow rate of the solution output from the second liquid outlet pipe, and both the first regulating valve and the second regulating valve may be known to those skilled in the art and may be commercially available.
In the present embodiment, the number of solution pools included in any two solution arrangement mechanisms is the same or different, and preferably, the number of solution pools included in m solution arrangement mechanisms increases sequentially from top to bottom in the direction of gravity, and n is equal to m + 1.
In this embodiment, m solution disposing mechanisms are sequentially arranged along the gravity direction, and m solution disposing mechanisms are further sequentially staggered along the horizontal direction, so that the m solution disposing mechanisms are integrally in a step-like structure.
In this embodiment, still be provided with a plurality of baffles 500 in the airtight chamber, solution configuration mechanism 200 is fixed to be set up on the baffle 500, and is wherein, a plurality of baffle 500 sets up along the direction of gravity interval in proper order, and simultaneously, it is a plurality of baffle 500 still staggers in proper order along the horizontal direction, thereby makes a plurality of baffle 500 wholly is the echelonment structure.
In this embodiment, the housing 100 may be formed by a plurality of acrylic plates connected and enclosed together, for example, the housing may be formed by a plurality of acrylic plates bonded together by a hot melt adhesive, and the plurality of solution dispensing mechanisms may be fixed in a closed chamber inside the housing by the hot melt adhesive.
In this embodiment, when the number of the solution distribution mechanisms is greater than or equal to 2, the solution concentrations in the plurality of first liquid outlet pipes in each of the branch pipes may be the same; and the rest can be done in the same way until the concentration of the solution in the solution pool in the solution configuration mechanism at the lowest layer is different, namely the concentration of the solution output from the second liquid outlet pipe is different.
In this embodiment, a stepped configuration device based on high-throughput microfluidics with different solution concentrations includes a first-stage solution configuration mechanism 210, a second-stage solution configuration mechanism 220, a third-stage solution configuration mechanism 230, a fourth-stage solution configuration mechanism 240, a fifth-stage solution configuration mechanism 250, a sixth-stage solution configuration mechanism 260, a seventh-stage solution configuration mechanism 270, and an eighth-stage solution configuration mechanism 280, which are sequentially arranged from top to bottom along a gravity direction, the eight solution configuration mechanisms are staggered from each other along a horizontal direction to form an integral stepped structure, correspondingly, the first-stage solution configuration mechanism 210 is a solution configuration mechanism at the topmost layer, a solution pool included in the first-stage solution configuration mechanism 210 is a first-stage solution pool or a first-stage pool body, a solution located in the first-stage solution pool is called a primary solution or a first-stage solution, the second-stage solution configuration mechanism 220 is a solution configuration mechanism at the second topmost layer, the solution pool included in the second-stage solution configuration mechanism is a second-stage solution pool or a second-stage pool body, the solution located in the second-stage solution pool is called a second-stage solution, and so on, the eight-stage solution configuration mechanism 280 is a solution configuration mechanism at the bottommost layer, the solution pool included in the eight-stage solution configuration mechanism is an eight-stage solution pool or an eight-stage pool body, and the solution located in the eight-stage solution pool is called an eight-stage solution, namely the target solution to be finally obtained.
In this embodiment, each stage of solution distribution mechanism includes one or more solution pools, and each solution distribution mechanism includes the same number of shunt tubes as the number of solution pools.
In this embodiment, the method for performing high-throughput configuration of different-concentration solutions based on the step configuration device for different-solution concentrations based on high-throughput microfluidics may include the following steps:
inputting a main solution into a first-stage tank body from a main solution inlet of a topmost solution configuration mechanism to obtain a first-stage solution, performing multi-flow-channel flow distribution through array-type flow distribution pipes, mixing the main solution in a second-stage tank body when the main solution flows into the second-stage tank body through the flow distribution pipes to obtain a second-stage solution, and performing multi-stage solution configuration by analogy to obtain a solution with a required concentration, wherein the inflow speed of the main solution is preferably 0.01-0.05 m/s, and the main solution is controlled to be input in a low-speed inflow mode to ensure that the solutions are fully mixed.
It will be understood that the solution tank in the topmost (or first) solution configuration means is referred to as a primary tank body, the solution tank in the next topmost (or second) solution configuration means is referred to as a secondary tank body, and so on.
In this embodiment, the number of shunt tubes and the number of solution reservoirs in each solution distribution mechanism are the same.
In this embodiment, after completing the preparation of a group of solutions, the solutions are output through the second liquid outlet pipe, and the next solution preparation can be started after the device is cleaned.
In this embodiment, the monitoring solution flow rate is preferably: the method comprises the steps of monitoring the change rule of the flow rate of a solution along with time, controlling the flow rate of the solution, recording the point flow rate Q and the corresponding time point t, drawing a Q-t curve, calculating the volume and mixing time of the solution in the mixing process, realizing high-throughput evaluation and calculation of the solution, evaluating the mixing degree of the solution through the flow rate curve measured by the flow rate, evaluating the uniformity of the solution through the dispersion degree of a solvent in the solution, finally realizing the high-throughput evaluation and calculation of the solution, and improving the configuration efficiency.
Example 1
The stepped configuration device based on high-throughput microfluidics and different solution concentrations as shown in fig. 1-6 is adopted to perform solution configuration with different concentration gradients, wherein the adopted main solutions are Atrazine (ATZ) solution (with the concentration of 80ppm) and deionized water (with the concentration of 0), the two main solutions with equal volume and equal flow rate flow into a main solution pool through a main solution inlet, and are subjected to uniform multi-channel shunting through an array type shunting pipe; with the circulation of the uniform shunt tubes, dividing the main solution into three streams, flowing into three secondary solution pools, and uniformly mixing in the secondary solution pools to obtain three Atrazine (ATZ) solutions with different concentration gradients of 0ppm, 40ppm and 80ppm, and marking as secondary solutions;
after the atrazine solution is uniformly mixed in the secondary solution pool, the secondary solution is uniformly divided by a flow dividing pipe of a second layer solution configuration mechanism, the secondary solution is divided into four strands and flows into the tertiary solution pool, and four Atrazine (ATZ) solutions with different concentration gradients, namely, 0, 1/3 x 80ppm, 2/3 x 80ppm and 80ppm are obtained after uniform mixing in the tertiary solution pool and are marked as tertiary solutions;
with the continuous passing of the Atrazine (ATZ) solution through the four-stage and five-stage solution pools, five Atrazine (ATZ) solutions with different concentrations of 0ppm, 20ppm, 40ppm, 60ppm and 80ppm can be obtained in the last five-stage solution pool after the Atrazine (ATZ) solution is uniformly mixed.
Liquid phase (HPLC) testing is performed on the obtained Atrazine (ATZ) solution, the obtained data (shown in table 1) are analyzed and fitted to obtain a fitted curve shown in fig. 7, and research shows that the linear characteristic of the fitted curve can meet the concentration error within the error range.
Table 1 shows the results of liquid phase tests on five Atrazine (ATZ) solutions of different concentrations
On the basis, the inventor also uses the instrument to carry out Sulfamethoxazole (SMX), Ciprofloxacin (CIP), sodium chloride (NaCl) and sodium sulfate (Na)28O4) Preparation of different concentration gradient solutions of equal aqueous solution, just as the preparation process of Atrazine (ATZ) solution in example 1, 80ppm Sulfamethoxazole (SMX), Ciprofloxacin (CIP), sodium chloride (NaCl), sodium sulfate (Na2SO4) aqueous solution and deionized water are flowed from the inlet of main solution at equal flow rate and equal flow rate through the second, third, fourth and fifth stage solution pools, and Sulfamethoxazole (SMX), Ciprofloxacin (CIP), sodium chloride (NaCl) and sodium sulfate (Na) are treated in the last fifth stage solution pool2SO4) The water solution is mixed uniformly to obtain five Sulfamethoxazole (SMX), Ciprofloxacin (CIP), sodium chloride (NaCl) and sodium sulfate (Na) with different concentrations of 0ppm, 20ppm, 40ppm, 60ppm and 80ppm2SO4) An aqueous solution of (a).
Sulfamethoxazole (SMX), Ciprofloxacin (CIP), sodium chloride (NaCl), sodium sulfate (Na) with different concentrations are obtained2SO4) The concentration of the aqueous solution was measured, and the obtained data were put into tables 2, 3, 4, and 5, and analyzed and fitted to obtain fitting curves as shown in fig. 8, 9, 10, and 11, respectively, which proved that the linear characteristic could satisfy the concentration error within the error range.
Table 2 shows the results of liquid phase tests on five Sulfamethoxazole (SMX) solutions of different concentrations
Table 3 shows the results of liquid phase tests of five Ciprofloxacin (CIP) solutions with different concentrations
Table 4 shows the results of liquid phase tests on five sodium chloride (NaCl) solutions of different concentrations
Table 5 shows five sodium sulfate (Na) concentrations2SO4) Liquid phase test results of the solution
According to the stepped configuration device based on high-flux microfluidics and provided by the embodiment of the utility model, under the condition that the type and concentration of the solution are determined, the solution of a single main system is input through the stepped solution mixing device to obtain the required solution with different concentration gradients, the liquid in the whole system is driven to flow by means of gravitational potential energy, multi-channel output of the solutions with different concentrations in a single preparation batch is realized, and the configuration efficiency of the solution is improved.
The stepped configuration device based on high-flux microfluidics and different solution concentrations, provided by the embodiment of the utility model, has a simple structure and is more convenient to use, the stepped configuration device can realize simultaneous addition of multiple solutions in a short time, sample solutions with multiple target concentrations are output at the same time, and the configuration efficiency of solutions with different concentration gradients is remarkably improved.
It should be understood that the above-mentioned embodiments are merely illustrative of the technical concepts and features of the present invention, and are intended to enable those skilled in the art to understand the contents of the present invention and implement the utility model, and not to limit the scope of the present invention. All equivalent changes and modifications made according to the spirit of the present invention should be covered in the protection scope of the present invention.
Claims (10)
1. A high throughput microfluidics based stepped configuration device of different solution concentrations, comprising: m solution allocation mechanisms which are sequentially arranged along the gravity direction, each solution allocation mechanism comprises n solution pools which are isolated from each other,
defining any two adjacent solution allocation mechanisms in the m solution allocation mechanisms as a first solution allocation mechanism and a second solution allocation mechanism, wherein the first solution allocation mechanism is positioned above the second solution allocation mechanism, each solution pool in the first solution allocation mechanism is also communicated with at least two selected solution pools in the second solution allocation mechanism, and the solution in one solution pool in the first solution allocation mechanism can automatically flow into at least two selected solution pools in the second solution allocation mechanism under the action of gravity; and the number of the first and second groups,
the solution tank contained in the solution configuration mechanism positioned at the topmost layer is also provided with a solution inlet, and the solution tank contained in the solution configuration mechanism positioned at the bottommost layer is also connected with a second liquid outlet pipe, wherein m is more than or equal to 2, and n is more than or equal to 2.
2. The stepped configuration device of claim 1, wherein: the solution pools in the first solution configuration mechanism and the second solution configuration mechanism are connected through the flow dividing pipe, the flow dividing pipe comprises a liquid inlet pipe and at least two first liquid outlet pipes, the liquid inlet pipe is communicated with the solution pools in the first solution configuration mechanism, one ends of the at least two first liquid outlet pipes are communicated with the liquid inlet pipe, and the other ends of the at least two first liquid outlet pipes are communicated with the at least two solution pools in the second solution configuration mechanism in a one-to-one correspondence manner.
3. The stepped configuration device of claim 2, wherein: at least two the length and the pipe diameter of first drain pipe are all the same.
4. The stepped configuration device of claim 2, wherein: still be provided with first governing valve on the first drain pipe, still be provided with first governing valve on the second drain pipe.
5. The stepped configuration device of claim 1, wherein: the number of the solution pools contained in any two solution preparation mechanisms is the same or different.
6. The stepped configuration device of claim 5, wherein: the number of the solution pools contained in the m solution allocation mechanisms is gradually increased from top to bottom along the gravity direction, and n is equal to m + 1.
7. The stepped configuration device of claim 1, wherein: each solution pool is closed; and/or the m solution allocation mechanisms are staggered in sequence along the horizontal direction, so that the m solution allocation mechanisms are in a stepped structure integrally.
8. The stepped configuration device of claim 1, further comprising: the shell is internally provided with a closed cavity, the m solution configuration mechanisms are arranged in the closed cavity, and at least the pipe orifice part of the second liquid outlet pipe is exposed and arranged outside the closed cavity; and/or the housing is formed by connecting transparent support plates.
9. The stepped configuration device of claim 8, wherein: the closed chamber is also provided with a plurality of clapboards, and the solution configuration mechanism is fixedly arranged on the clapboards.
10. The stepped configuration device of claim 9, wherein: it is a plurality of the baffle sets up along the direction of gravity interval in proper order, and simultaneously, it is a plurality of the baffle still staggers in proper order along the horizontal direction to it is a plurality of to make the baffle wholly be the echelonment structure.
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