CN216728519U - Immunohistochemical film developing device - Google Patents
Immunohistochemical film developing device Download PDFInfo
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- CN216728519U CN216728519U CN202220033079.8U CN202220033079U CN216728519U CN 216728519 U CN216728519 U CN 216728519U CN 202220033079 U CN202220033079 U CN 202220033079U CN 216728519 U CN216728519 U CN 216728519U
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- Prior art keywords
- groove
- spring
- immunohistochemical
- hole
- ring
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- 230000002055 immunohistochemical effect Effects 0.000 title claims abstract description 20
- 230000007246 mechanism Effects 0.000 claims abstract description 43
- 238000001914 filtration Methods 0.000 claims abstract description 22
- 238000012545 processing Methods 0.000 claims description 9
- 238000005406 washing Methods 0.000 abstract description 11
- 210000004556 brain Anatomy 0.000 description 35
- 239000007788 liquid Substances 0.000 description 22
- 230000008859 change Effects 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000003364 immunohistochemistry Methods 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 1
- 238000003365 immunocytochemistry Methods 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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Abstract
The utility model relates to the technical field of medical instruments and discloses an immunohistochemical film washing device which comprises a plate body, wherein a plurality of hole grooves are formed in the plate body, and a filtering mechanism is inserted into each hole groove; the filter mechanism comprises a top ring, a bottom ring and a plurality of connecting rods connected between the top ring and the bottom ring, a cavity is formed between every two adjacent connecting rods, a first filter screen is arranged in the cavity, and an annular second filter screen is embedded at the bottom of the bottom ring.
Description
Technical Field
The utility model belongs to the technical field of medical instruments, and particularly relates to an immunohistochemical film washing device.
Background
Immunohistochemistry is a research on the localization, qualitative and relative quantification of antigens (polypeptides and proteins) in tissue cells by applying the principle of antigen-antibody reaction, namely the principle of specific combination of antigens and antibodies, which is the basic principle of immunology, and allowing color development agents (fluorescein, enzyme, metal ions and isotopes) of labeled antibodies to develop through chemical reaction, and is called immunohistochemistry technology or immunocytochemistry technology. In the immunohistochemical experiment process, the brain slice bearing the sample is usually cleaned for many times to remove residual liquid on the brain slice, so that mutual interference of reagents is prevented, and the immunohistochemical experiment is facilitated. But current immunohistochemical film processing device need pick the piece repeatedly when trading the liquid, causes the damage to the brain piece easily to the step is loaded down with trivial details, is not convenient for trade liquid fast, can not realize high-efficient film processing, and in addition, the film processing is accomplished the back, can not be with the brain piece by jacking in the filtering mechanism, the quick of the brain piece of not being convenient for takes out, still need pick out the brain piece by in the filtering mechanism, not only leads to the brain piece damage easily, still causes taking out inefficiency of brain piece.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide an immunohistochemical developing device to solve the problems that during liquid changing, the developing device needs to repeatedly pick the developing device, brain slices are easily damaged, steps are complicated, liquid is inconvenient to quickly change, and the brain slices cannot be lifted up from a filtering mechanism and cannot be quickly taken out.
In order to achieve the purpose, the utility model provides the following technical scheme: an immunohistochemical film washing device comprises a plate body, wherein a plurality of hole grooves are formed in the plate body, and a filtering mechanism is inserted into each hole groove; the filtering mechanism comprises a top ring, a bottom ring and a plurality of connecting rods connected between the top ring and the bottom ring, wherein cavities are formed between the connecting rods, a first filter screen is arranged in each cavity, and a second filter screen which is annular is embedded in the bottom of the bottom ring.
Preferably, still include ejection mechanism, ejection mechanism is including seting up groove, spring groove and the through-hole of accomodating in the middle of the bottom ring, the inside of accomodating the groove is equipped with the liftout plate, the spring groove is equipped with two altogether, and two spring groove symmetric distribution in the both sides of through-hole, two spring groove and through-hole all with accomodate the groove intercommunication, and the inside in two spring grooves all is fixed with the spring, the top of spring is connected with the bottom of liftout plate.
Preferably, the filtering mechanism further comprises a limiting assembly, the limiting assembly comprises a limiting strip installed on one side of the connecting rods and a limiting groove formed in the inner wall of the hole groove, and the limiting groove corresponds to the limiting strip in a one-to-one mode.
Preferably, a handle is installed on one side of the top ring, and an arc portion is formed at one end, far away from the top ring, of the handle.
Preferably, the inside of the spring groove is also provided with a telescopic linkage rod, two ends of the linkage rod are respectively connected with the bottom of the inside of the spring groove and the bottom of the ejector plate, and the spring sleeve is arranged outside the linkage rod.
Preferably, the top and the bottom of the limiting strip are both provided with inclined parts, and the bottom of the inner part of the limiting groove is provided with an inclined surface matched with the inclined parts at the bottom of the limiting strip.
Compared with the prior art, the utility model has the beneficial effects that:
(1) according to the utility model, through the arrangement of the filtering mechanism, when liquid is replaced, the filtering mechanism is only required to be pulled out of the hole groove, and then the liquid accumulated in the hole groove on the plate body is poured and replaced, so that the liquid is replaced quickly, the brain slices are not required to be picked out in advance, the liquid replacing step is simplified, the problem that the brain slices are damaged by repeatedly picking the immunohistochemical film washing is effectively solved, the immunohistochemical film washing is ensured, and the high-efficiency film washing can be realized.
(2) According to the utility model, the brain slice can be jacked up from the filtering mechanism through the jacking mechanism, and the brain slice can be prevented from being adsorbed in the filtering mechanism, so that the brain slice can be quickly taken out, a user does not need to pick out the brain slice from the filtering mechanism, the brain slice taking-out efficiency is effectively improved, the brain slice can be prevented from being damaged, and the use of the brain slice is ensured.
Drawings
FIG. 1 is a schematic view of the structure of the present invention;
FIG. 2 is a schematic view of the filter mechanism of the present invention after disassembly;
FIG. 3 is a cross-sectional view of the filter mechanism of the present invention;
FIG. 4 is a front view of the filter mechanism of the present invention;
FIG. 5 is an enlarged view taken at A in FIG. 1;
in the figure: 1. a plate body; 2. a filtering mechanism; 21. a top ring; 22. a bottom ring; 23. a connecting rod; 24. a first filter screen; 25. a second filter screen; 26. a handle; 3. an ejection mechanism; 31. a storage groove; 32. ejecting the plate; 33. a through hole; 34. a spring; 35. a spring slot; 4. a hole groove; 5. a limiting groove; 6. and (5) a limiting strip.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides the following technical solutions: an immunohistochemical film washing device comprises a plate body 1, wherein a plurality of hole grooves 4 are formed in the plate body 1, and a filtering mechanism 2 is inserted into each hole groove 4; the filter mechanism 2 comprises a top ring 21, a bottom ring 22 and a plurality of connecting rods 23 connected between the top ring 21 and the bottom ring 22, a cavity is formed between every two adjacent connecting rods 23, a first filter screen 24 is arranged in the cavity, and a second filter screen 25 which is annular is embedded at the bottom of the bottom ring 22.
A handle 26 is mounted on one side of the top ring 21, and an arc portion is formed at one end of the handle 26 far away from the top ring 21.
Through the technical scheme:
when the brain slice cleaning machine is used, a user can firstly insert the filter mechanism 2 into the hole groove 4 through the handle 26, put a brain slice into the filter mechanism 2 and then add cleaning liquid into the filter mechanism 2 to clean the brain slice, at the moment, cell liquid can flow into the hole groove 4 through the first filter screen 24 and the second filter screen 25 to be stored, and therefore the brain slice cleaning is achieved;
meanwhile, when liquid needs to be changed, a user can pull out the filtering mechanism 2 from the hole groove 4 through the handle 26, then pour the liquid accumulated in the hole groove 4 on the plate body 1 to change the liquid in the hole groove 4, and then insert the filtering mechanism 2 into the hole groove 4 to continuously clean the brain slice, so that the quick liquid change is realized, the brain slice does not need to be picked out in advance, the liquid changing step is simplified, the problem that the brain slice is damaged by repeatedly picking the immunohistochemical washing slice is effectively solved, the immunohistochemical washing slice is ensured to be carried out, and the high-efficiency washing slice can be realized;
in addition, in the present embodiment, there are 6 hole slots 4, but in the practical application, the number may be selected according to the requirement, and is not limited herein.
Referring to fig. 1, 3 and 5, the ejection device 3 further includes an ejection mechanism 3, the ejection mechanism 3 includes a receiving groove 31, a spring groove 35 and a through hole 33, the receiving groove 31 is provided with an ejection plate 32 therein, the number of the spring grooves 35 is two, the two spring grooves 35 are symmetrically distributed on two sides of the through hole 33, the two spring grooves 35 and the through hole 33 are both communicated with the receiving groove 31, the springs 34 are fixed inside the two spring grooves 35, and the top ends of the springs 34 are connected to the bottom of the ejection plate 32.
The inside of spring groove 35 still is equipped with telescopic gangbar, and the both ends of gangbar are connected with the inside bottom of spring groove 35 and the bottom of liftout plate 32 respectively, and the outside of gangbar is located to the spring 34 cover.
Through the technical scheme:
when the washing is completed, and the user takes out the brain slice from the filtering mechanism 2, the user can take a thin rod, the thin rod is inserted into the through hole 33 to push the ejecting plate 32 in the accommodating groove 31 upwards, so that the ejecting plate 32 is moved out of the accommodating groove 31, and the brain slice in the filtering mechanism 2 is lifted upwards, at the moment, the spring 34 in the spring groove 35 is stretched along with the spring, and then the user takes the brain slice down from the ejecting plate 32, after the brain slice is taken down, the user pulls out the thin rod from the through hole 33, at the moment, the ejecting plate 32 is taken into the accommodating groove 31 under the action of the spring 34, so that the ejection plate 32 is accommodated, the brain slice is taken out quickly, the brain slice does not need to be picked out of the filtering mechanism 2 by the user, the brain slice taking-out efficiency is effectively improved, the brain slice can be prevented from being damaged, and the use of the brain slice is ensured.
Referring to fig. 2-4, the filtering mechanism 2 further includes a limiting component, the limiting component includes a limiting strip 6 mounted on one side of the plurality of connecting rods 23 and a limiting groove 5 formed in the inner wall of the hole groove 4, and the limiting grooves 5 correspond to the limiting strips 6 one to one.
Through the technical scheme:
when the filter mechanism 2 is inserted into the hole groove 4, the limiting strip 6 can be inserted into the limiting groove 5 along with the filter mechanism and slide along the limiting groove 5, so that the position between the filter mechanism 2 and the plate body 1 is limited, and the stable work of the filter mechanism 2 is facilitated.
Referring to fig. 2 and 4, the top and bottom of the spacing bar 6 are formed with inclined portions, and the bottom of the inside of the spacing groove 5 is formed with an inclined surface matching the inclined portions at the bottom of the spacing bar 6.
Through the technical scheme:
when the liquid draining device is used, when liquid flows into the limiting groove 5, the inclined surface of the bottom plate of the limiting groove 5 can guide the liquid to drain the liquid out of the limiting groove 5, so that the liquid is prevented from accumulating in the limiting groove 5, and the liquid is convenient to drain.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. An immunohistochemical film processing device is characterized in that: the plate comprises a plate body (1), wherein a plurality of hole grooves (4) are formed in the plate body (1), and a filtering mechanism (2) is inserted into each hole groove (4); filtering mechanism (2) are including apical ring (21), end ring (22) and a plurality of connecting rod (23) of connecting between apical ring (21) and end ring (22), adjacent two all form the cavity between connecting rod (23), and are equipped with first filter screen (24) in the cavity, the bottom of end ring (22) is inlayed and is equipped with and is annular second filter screen (25).
2. The immunohistochemical film processing device according to claim 1, wherein: still include ejection mechanism (3), ejection mechanism (3) are including seting up groove (31), spring groove (35) and through-hole (33) of accomodating in the middle of bottom ring (22), the inside of accomodating groove (31) is equipped with liftout plate (32), spring groove (35) are equipped with two altogether, and two spring groove (35) symmetric distribution in the both sides of through-hole (33), two spring groove (35) and through-hole (33) all with accomodate groove (31) intercommunication, and the inside of two spring grooves (35) all is fixed with spring (34), the top of spring (34) is connected with the bottom of liftout plate (32).
3. The immunohistochemical film processing device according to claim 1, wherein: the filter mechanism (2) further comprises a limiting assembly, the limiting assembly comprises limiting strips (6) arranged on one sides of the connecting rods (23) and limiting grooves (5) formed in the inner wall of the hole groove (4), and the limiting grooves (5) correspond to the limiting strips (6) one to one.
4. The immunohistochemical film processing device according to claim 1, wherein: a handle (26) is installed on one side of the top ring (21), and an arc portion is formed at one end, far away from the top ring (21), of the handle (26).
5. An immunohistochemical film processing device according to claim 2, wherein: the inside of spring groove (35) still is equipped with telescopic gangbar, and the both ends of gangbar are connected with the inside bottom of spring groove (35) and the bottom of liftout plate (32) respectively, the outside of gangbar is located in the cover of spring (34).
6. An immunohistochemical film processing device according to claim 3, wherein: the top and the bottom of spacing strip (6) all are formed with the rake, the inside bottom of spacing groove (5) is formed with the rake assorted inclined plane with spacing strip (6) bottom.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220033079.8U CN216728519U (en) | 2022-01-07 | 2022-01-07 | Immunohistochemical film developing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202220033079.8U CN216728519U (en) | 2022-01-07 | 2022-01-07 | Immunohistochemical film developing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216728519U true CN216728519U (en) | 2022-06-14 |
Family
ID=81911867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202220033079.8U Expired - Fee Related CN216728519U (en) | 2022-01-07 | 2022-01-07 | Immunohistochemical film developing device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216728519U (en) |
-
2022
- 2022-01-07 CN CN202220033079.8U patent/CN216728519U/en not_active Expired - Fee Related
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|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20220614 |
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| CF01 | Termination of patent right due to non-payment of annual fee |