CN216499436U

CN216499436U - Air pressure supply device

Info

Publication number: CN216499436U
Application number: CN202121905225.3U
Authority: CN
Inventors: 董久源; 蔡松锜
Original assignee: Laifu Kede Biotechnology Co ltd
Current assignee: Dong Jiuyuan
Priority date: 2021-08-13
Filing date: 2021-08-13
Publication date: 2022-05-13
Anticipated expiration: 2031-08-13

Abstract

The present disclosure provides an air pressure supply device for supplying air pressure to a detection device, the air pressure supply device including: a body; the bearing table is arranged on the body and used for bearing the detection device; a positive pressure motor arranged on the body and used for generating positive pressure; the negative pressure motor is arranged on the body and used for generating negative pressure; the first electromagnetic valve is provided with two first inlets and a first outlet, wherein the two first inlets are respectively connected with the positive pressure motor and the negative pressure motor and used for controlling positive pressure or negative pressure to pass through; and the second electromagnetic valve is provided with a second inlet, an atmospheric port and a second outlet, wherein the second inlet is connected with the first outlet of the first electromagnetic valve and used for positive pressure or negative pressure to pass through, the atmospheric port is used for providing normal pressure to pass through, and the second outlet is connected with the detection device and used for providing the positive pressure, the negative pressure or the normal pressure to the detection device through the second electromagnetic valve.

Description

Air pressure supply device

Technical Field

The present disclosure relates to an air pressure supply device for providing air pressure to a detection device, and more particularly, to an air pressure supply device capable of providing micro-positive pressure, micro-negative pressure, positive pressure, negative pressure, or normal pressure.

Background

Circulating Tumor Cells (CTCs) have been widely used as a potential tool for diagnosis and prognosis of cancer, as their presence in the blood may suggest metastatic relapse. In order to detect rare CTCs in blood samples, automatic, rapid and sensitive detection devices have been developed that are capable of performing all experimental procedures without any manual intervention. The detection device requires the air pressure supply device to provide air pressure to actuate the pump and the valve in the detection device. However, the conventional air pressure supply device cannot provide a small air pressure, which often results in the membrane of the pump being damaged and unusable, and the conventional air pressure supply device cannot provide a normal pressure, which prevents the membrane of the pump from returning to a flat state during the detection process, thereby causing cell damage.

Therefore, the applicant finally devised the "air pressure supply device" in order to improve the above-mentioned drawbacks of the prior art through careful experiments and studies and with no intention of abandoning the spirit.

SUMMERY OF THE UTILITY MODEL

The air pressure supply device can provide larger positive and negative air pressure to regulate and control the actuation of the valve in the detection device, can also provide small positive and negative air pressure through the positive pressure fine adjustment valve and the negative pressure fine adjustment valve, and can provide normal pressure through the atmospheric port of the electromagnetic valve so as to regulate and control the actuation of the pump in the detection device more precisely.

An aspect of the present disclosure is to provide an air pressure supply device for supplying positive pressure, negative pressure, or normal pressure to a micro flow channel chip, wherein the micro flow channel chip includes a first pump, and the air pressure supply device includes: a body; a bearing platform arranged on the body and used for bearing the micro-channel chip; a positive pressure motor arranged on the body for generating the positive pressure; a negative pressure motor arranged on the body for generating the negative pressure; the first positive pressure fine adjusting valve is connected with the positive pressure motor and used for precisely adjusting the positive pressure to generate a first micro positive pressure; the first negative pressure fine adjustment valve is connected with the negative pressure motor and used for precisely adjusting the magnitude of the negative pressure to generate first micro negative pressure; the first electromagnetic valve is provided with two first inlets and a first outlet, wherein the two first inlets are respectively connected with the first positive pressure fine regulating valve and the first negative pressure fine regulating valve and used for controlling the first micro positive pressure or the first micro negative pressure to pass through; and a second solenoid valve having a second inlet, a first atmospheric port and a second outlet, wherein the second inlet is connected to the first outlet of the first solenoid valve for allowing the first micro-positive pressure or the first micro-negative pressure to pass through, the first atmospheric port is used for allowing the normal pressure to pass through, the second outlet is connected to the first pump of the micro-channel chip, and the first micro-positive pressure, the first micro-negative pressure or the normal pressure is provided to the micro-channel chip through the second solenoid valve, thereby actuating the first pump.

Another aspect of the present disclosure is to provide an air pressure supplying apparatus to supply air pressure to a detecting apparatus, including: a body; the bearing table is arranged on the body and used for bearing the detection device; a positive pressure motor arranged on the body for generating positive pressure; a negative pressure motor arranged on the body for generating negative pressure; the first electromagnetic valve is provided with two first inlets and a first outlet, wherein the two first inlets are respectively connected with the positive pressure motor and the negative pressure motor and used for controlling the positive pressure or the negative pressure to pass through; and the second electromagnetic valve is provided with a second inlet, an atmosphere port and a second outlet, wherein the second inlet is connected with the first outlet of the first electromagnetic valve and used for allowing the positive pressure or the negative pressure to pass through, the atmosphere port is used for allowing the normal pressure to pass through, the second outlet is connected with the detection device, and the positive pressure, the negative pressure or the normal pressure is provided to the detection device through the second electromagnetic valve.

Another aspect of the present disclosure is to provide an air pressure supply device to supply air pressure to a detection device, including: a body; the bearing platform is arranged on the body and used for bearing the detection device; a positive pressure motor arranged on the body for generating the positive pressure; the negative pressure motor is arranged on the body and used for generating the negative pressure; the positive pressure fine adjustment valve is connected with the positive pressure motor and used for precisely adjusting the positive pressure to generate micro positive pressure; the negative pressure fine adjustment valve is connected with the negative pressure motor and used for precisely adjusting the negative pressure to generate micro negative pressure; and the electromagnetic valve is provided with two inlets and an outlet, wherein the two inlets are respectively connected with the positive pressure fine adjustment valve and the negative pressure fine adjustment valve and used for controlling the micro positive pressure or the micro negative pressure to pass through, and the outlet is connected with the detection device and used for providing the micro positive pressure or the micro negative pressure to the detection device.

In order to make the aforementioned and other objects, features and advantages of the present disclosure comprehensible, preferred embodiments accompanied with figures are described in detail below.

Drawings

Fig. 1 is a schematic configuration diagram of an air pressure supply device of the present disclosure.

Fig. 2 is a schematic view of an embodiment of a detection device to which the air pressure supply device of the present disclosure is applied.

Fig. 3 is a schematic view of an embodiment of the air pressure supply device of the present disclosure applied to a detection device.

Detailed Description

Although the embodiments of the "air pressure supply apparatus" will be described with reference to the accompanying drawings, the actual configuration and the method to be implemented do not necessarily conform to the description, and those skilled in the art can make various changes and modifications without departing from the true spirit and scope of the present disclosure.

The air pressure supply device of the present disclosure is used to supply air pressure to the detection device, and in the example of the present disclosure, the detection device may be a micro flow channel chip that detects biological substances (such as circulating tumor cells, fetal cells, bacteria, viruses, epithelial cells, endothelial cells, etc.) in a biological fluid sample (such as blood, body fluid, or bacteria solution, etc.).

Please refer to fig. 1, which is a schematic configuration diagram of an air pressure supply device according to the present disclosure. The air pressure supply device 20 of the present disclosure includes a body 210, and the body 210 includes an upper layer 212 and a lower layer 214. The air pressure supply device 20 further includes a positive pressure supply source 220, a negative pressure supply source 230, a positive pressure fine adjustment valve 240, a negative pressure fine adjustment valve 250, a first solenoid valve set 260, a second solenoid valve set 270, and a carrying table 280 for carrying the inspection apparatus 10. The positive pressure supply source 220 includes a positive pressure motor 222 and a positive pressure gas distribution groove 224 respectively disposed on the lower layer 214 and the upper layer 212 of the body 210, the positive pressure motor 222 is connected to the positive pressure gas distribution groove 224 through a gas pipe, and the positive pressure gas generated by the positive pressure motor 222 is stored in the positive pressure gas distribution groove 224 to provide the positive pressure. The negative pressure supply source 230 includes a negative pressure motor 232 and a negative pressure distribution groove 234 respectively disposed on the lower layer 214 and the upper layer 212 of the body 210, the negative pressure motor 232 and the negative pressure distribution groove 234 are connected by an air pipe, and the vacuum suction force generated by the negative pressure motor 232 is stored in the negative pressure distribution groove 234 to provide the negative pressure.

The air pressure supply device 20 of the present disclosure can provide micro positive pressure, micro negative pressure and normal pressure to the detection device 10, and the micro air pressure supply path is from the positive pressure distribution tank 224 and the negative pressure distribution tank 234 to the detection device 10 through the positive pressure micro-regulating valve 240, the negative pressure micro-regulating valve 250, the first electromagnetic valve 262 and the second electromagnetic valve 272. The positive pressure fine adjustment valve 240 is connected to the positive pressure gas distribution groove 224 through a gas pipe, and when the positive pressure gas passes through the positive pressure fine adjustment valve 240, the pressure of the positive pressure gas can be adjusted to 1-6 psi, so as to provide a micro positive pressure. The negative pressure fine adjustment valve 250 is connected to the negative pressure distribution groove 234 through an air pipe, and when the vacuum suction force passes through the negative pressure fine adjustment valve 250, the pressure of the vacuum suction force can be adjusted to-1-6 psi so as to provide the micro negative pressure. The positive pressure trim valve 240 and the negative pressure trim valve 250 of the present disclosure may be precise to ± 0.01 psi. The first solenoid valve 262 includes two inlets and one outlet, wherein the two inlets of the first solenoid valve 262 are respectively connected to the positive pressure fine adjustment valve 240 and the negative pressure fine adjustment valve 250 through air pipes, and the controller 350 disposed at the lower layer 214 of the body 210 controls which inlet is to be opened, and the micro positive pressure generated by the positive pressure fine adjustment valve 240 or the micro negative pressure generated by the negative pressure fine adjustment valve 250 passes through and is delivered to the outlet of the first solenoid valve 262. The second solenoid valve 272 includes an inlet, an atmospheric port 273 and an outlet, wherein the inlet of the second solenoid valve 272 is connected to the outlet of the first solenoid valve 262 through a gas pipe, so that the micro-positive pressure or the micro-negative pressure from the first solenoid valve 262 can pass through, the atmospheric port 273 of the second solenoid valve 272 can pass through the atmosphere to provide the atmospheric pressure, and the second solenoid valve 272 can control which inlet is to be opened, passed through by the micro-positive pressure or the micro-negative pressure or the atmospheric pressure, and sent to the outlet of the second solenoid valve 272 through the controller 350 disposed at the lower layer 214 of the body 210. The outlet of the second solenoid valve 272 is connected to the detecting device 10 through a gas pipe to provide a micro positive pressure, a micro negative pressure or a normal pressure to the detecting device 10. The air pressure supply device 20 of the present disclosure may further include a pressure sensor 310 disposed on the air pipe between the outlet of the second solenoid valve 272 and the detection device 10 for sensing the magnitude of the micro positive pressure or the micro negative pressure to determine the magnitude of the pressure input to the detection device 10.

In the present disclosure, when the air pressure supply device 20 is to provide a micro positive pressure to the detection device 10, it is required to open the inlet of the first solenoid valve 262 connected to the positive pressure fine adjustment valve 240 and open the inlet of the second solenoid valve 272 connected to the first solenoid valve 262. When the air pressure supply device 20 is to provide micro negative pressure to the detecting device 10, it is necessary to open the inlet of the first solenoid valve 262 connected to the negative pressure fine adjustment valve 250 and open the inlet of the second solenoid valve 272 connected to the first solenoid valve 262. When the atmospheric pressure supply device 20 is to supply the atmospheric pressure to the detection device 10, the atmospheric port 273 of the second solenoid valve 272 needs to be opened.

The pneumatic supply device 20 of the present disclosure may include a plurality of sets of positive pressure trim valve 240, negative pressure trim valve 250, first solenoid valve 262 and second solenoid valve 272 for different detection devices 10. That is, the air pressure supply device 20 of the present disclosure may have more than 2 lines to supply the micro positive pressure, the micro negative pressure and the normal pressure to the detection device 10.

The air pressure supply device 20 of the present disclosure may also provide positive pressure, negative pressure and normal pressure to the detection device 10, and the air pressure supply path is from the positive pressure distribution tank 224 and the negative pressure distribution tank 234 to the detection device 10 through the first solenoid valve 264 and the second solenoid valve 274. Since the air pressure supply path does not pass through the positive pressure trim valve 240 and the negative pressure trim valve 250, the positive pressure and the negative pressure are provided at + -0.1-12 psi. Similarly, the first solenoid valve 264 includes two inlets and one outlet, wherein the two inlets of the first solenoid valve 264 are respectively connected to the positive pressure distribution tank 224 and the negative pressure distribution tank 234 through air pipes, and the controller 350 disposed at the lower layer 214 of the body 210 controls which inlet is to be opened, and the positive pressure generated by the positive pressure distribution tank 224 or the negative pressure generated by the negative pressure distribution tank 234 passes through and is delivered to the outlet of the first solenoid valve 264. The second solenoid valve 274 includes an inlet, an atmospheric port 275 and an outlet, wherein the inlet of the second solenoid valve 274 is connected to the outlet of the first solenoid valve 264 through a gas pipe, and allows the positive pressure or the negative pressure from the first solenoid valve 264 to pass through, the atmospheric port 275 of the second solenoid valve 274 allows the atmospheric pressure to pass through to provide the atmospheric pressure, and the second solenoid valve 274 can control which inlet is to be opened, passed through by the positive pressure or the negative pressure or the atmospheric pressure, and sent to the outlet of the second solenoid valve 274 through the controller 350 disposed at the lower layer 214 of the body 210. The outlet of the second solenoid valve 274 is connected to the detection device 10 with a gas pipe to supply positive or negative pressure or normal pressure to the detection device 10.

In the present disclosure, when the air pressure supply device 20 is to provide positive pressure to the detection device 10, it is necessary to open the inlet of the first solenoid valve 264 connected to the positive pressure air distribution groove 224 and open the inlet of the second solenoid valve 274 connected to the first solenoid valve 264. When the air pressure supply device 20 is to provide negative pressure to the detection device 10, it is necessary to open the inlet of the first solenoid valve 264 connected to the negative pressure distribution tank 234 and open the inlet of the second solenoid valve 274 connected to the first solenoid valve 264. When the atmospheric pressure is to be supplied from the atmospheric pressure supply device 20 to the detection device 10, the atmospheric port 275 of the second electromagnetic valve 274 needs to be opened.

The pneumatic supply device 20 of the present disclosure may include a plurality of sets of the first solenoid valve 264 and the second solenoid valve 274 for different detection devices 10. That is, the air pressure supply device 20 of the present disclosure may have more than 2 lines to supply positive pressure, negative pressure and normal pressure to the detection device 10.

The pneumatic supply device 20 of the present disclosure may also provide only negative pressure and normal pressure to the detection device 10, and the pneumatic supply path is from the negative pressure distribution groove 234 to the detection device 10 through the first solenoid valve 266 and the second solenoid valve 276. Since the air pressure supply path does not pass through the positive pressure micro-regulating valve 240, the negative pressure micro-regulating valve 250 and the positive pressure air distribution groove 224, the pressure of the negative pressure is-0.1 to 12 psi. Similarly, the first solenoid valve 266 includes two inlets and one outlet, wherein the two inlets of the first solenoid valve 266 are respectively connected to the positive pressure distribution groove 224 and the negative pressure distribution groove 234 through air pipes, and the controller 350 disposed at the lower layer 214 of the body 210 controls the negative pressure generated by the negative pressure distribution groove 234 to pass through and be conveyed to the outlet of the first solenoid valve 264. The second solenoid valve 276 includes an inlet, an atmosphere port 277 and an outlet, wherein the inlet of the second solenoid valve 276 is connected to the outlet of the first solenoid valve 266 by a gas pipe, and allows the negative pressure from the first solenoid valve 266 to pass through, the atmosphere port 277 of the second solenoid valve 276 allows the atmosphere to pass through to provide the normal pressure, and the second solenoid valve 276 can control which inlet is opened by the controller 350 disposed at the lower layer 214 of the body 210, and is passed through by the negative pressure or the normal pressure and sent to the outlet of the second solenoid valve 276. The outlet of the second solenoid valve 276 is connected to the detecting device 10 through a gas pipe to supply negative pressure or normal pressure to the detecting device 10. The pneumatic supply device 20 of the present disclosure may further include a collecting tank 320 disposed between the outlet of the second solenoid valve 276 and the detection device 10 for collecting the waste liquid in the detection device 10 by the negative pressure provided.

In this path, when the air pressure supply device 20 is to provide negative pressure to the detection device 10, it is necessary to open the inlet of the first solenoid valve 266 connected to the negative pressure distribution groove 234 and open the inlet of the second solenoid valve 276 connected to the first solenoid valve 266. When the atmospheric pressure is to be supplied from the atmospheric pressure supply device 20 to the detection device 10, the atmospheric port 277 of the second electromagnetic valve 276 needs to be opened.

The air pressure supply device 20 of the present disclosure conveys the micro positive pressure, the micro negative pressure, the positive pressure, the negative pressure, and the normal pressure to the detection device 10 through three paths to perform different functions. In addition, the air pressure supply device 20 of the present disclosure may control the air pressure supply device 20 to automatically operate through a computer or other electronic devices.

The pneumatic pressure supply device 20 of the present disclosure further includes a magnetic device 330 disposed on the lower layer 214 of the body 210 and below the susceptor 280. The magnetic device 330 may generate a magnetic field to attract the magnetic substance in the detection device 10. The magnetic device 330 can be moved to close to the carrier 280, or even close to the bottom of the carrier 280.

The bottom of the carrier 280 of the air pressure supply device 20 of the present disclosure is a heating device 282, which can heat the detecting device 10. The air pressure supply device 20 of the present disclosure further includes at least one fan 340 disposed on the lower layer 214 of the body 210, and configured to cool the detection device 10.

Examples

In an embodiment of the present disclosure, the detection device 10 is a micro-fluidic chip 100 as shown in fig. 2. The lower layer of the micro flow channel chip 100 is a liquid channel through which a biological liquid sample flows, and the upper layer is a gas channel through which gas passes. The micro flow channel chip 100 includes a first pump 110, a second pump 120, 8 valves 130A-130H and a collection region 140, and the first pump 110, the second pump 120 and the 8 valves 130A-130H are actuated by applying air pressure provided by the air pressure supply device 400 to the air channels of the micro flow channel chip 100.

Please refer to fig. 3, which is a schematic diagram of an embodiment of the air pressure supply device applied to the micro flow channel chip 100. Referring to fig. 2 to 3, in the embodiment of the disclosure, the micro flow channel chip 100 is disposed on the carrier 280 (as shown in fig. 1) of the air pressure supply device 400, and the air pressure supply device 400 provides 12 sets of air pressure paths, including 2 sets of paths providing micro positive pressure, micro negative pressure or normal pressure, 8 sets of paths providing positive pressure, negative pressure or normal pressure, 1 set of paths providing negative pressure or normal pressure, and 1 set of air pressure paths, so as to conform to the micro flow channel chip 100 shown in fig. 2.

The 2 sets of the air pressure supply device 400 provide micro positive pressure, micro negative pressure or normal pressure paths as a first micro air pressure path and a second micro air pressure path, which respectively activate the first pump 110 and the second pump 120 of the micro flow channel chip 100. The first micro-pressure path is that the positive pressure motor 222 provides positive pressure to the first positive pressure micro-regulating valve 242 through the positive pressure gas distribution groove 224 to generate first micro-positive pressure, the negative pressure motor 232 provides negative pressure to the first negative pressure micro-regulating valve 252 through the negative pressure gas distribution groove 234 to generate first micro-negative pressure, the generated first micro-positive pressure and first micro-negative pressure are provided to the first electromagnetic valve 411, the first electromagnetic valve 411 controls the first micro-positive pressure or first micro-negative pressure to be conveyed to the second electromagnetic valve 412, and the second electromagnetic valve 412 controls the first micro-positive pressure or first micro-negative pressure or normal pressure to be conveyed to the micro-channel chip 100, so that the first pump 110 is actuated. The second micro-pressure path provides positive pressure to the second positive pressure micro-regulating valve 244 through the positive pressure distribution groove 224 for the positive pressure motor 222 to generate second micro-positive pressure, the negative pressure motor 232 provides negative pressure to the second negative pressure micro-regulating valve 254 through the negative pressure distribution groove 234 for the negative pressure motor to generate second micro-negative pressure, the generated second micro-positive pressure and second micro-negative pressure are provided to the first electromagnetic valve 421, the first electromagnetic valve 421 controls the second micro-positive pressure or second micro-negative pressure to be conveyed to the second electromagnetic valve 422, and the second electromagnetic valve 422 controls the second micro-positive pressure or second micro-negative pressure or normal pressure to be conveyed to the micro-channel chip 100 for actuating the second pump 120. Similarly, the first and second micro-pressure paths may be respectively provided with a first pressure sensor 312 and a second pressure sensor 314 for respectively sensing the magnitude of the first micro-positive pressure or the first micro-negative pressure and the magnitude of the second micro-positive pressure or the second micro-negative pressure.

In this embodiment, the first pump 110 and the second pump 120 of the micro flow channel chip 100 cause the liquid flow in the liquid channel by the rise and fall of the respective membranes. When the air pressure supply device 400 provides micro positive pressure to the first pump 110 and the second pump 120 of the micro flow channel chip 100, the membranes of the first pump 110 and the second pump 120 are pressed down. When the air pressure supply device 400 provides a micro negative pressure to the first pump 110 and the second pump 120 of the microchannel chip 100, the membranes of the first pump 110 and the second pump 120 rise. When the air pressure supply device 400 supplies normal pressure to the first pump 110 and the second pump 120 of the microchannel chip 100, the thin films of the first pump 110 and the second pump 120 are in a flat state. Since the first pump 110 and the second pump 120 of the micro flow channel chip 100 are operated by a thin film to make the liquid in the liquid channel of the micro flow channel chip 100 flow, if the positive pressure and the negative pressure are provided too much, the thin film is damaged and can not be used, so the first micro air pressure path and the second micro air pressure path can provide micro air pressure, and the thin film of the first pump 110 and the second pump 120 can not be damaged under the condition of maximum liquid flow. In addition, the first micro-air pressure path and the second micro-air pressure path can also provide normal pressure, so that the film can be restored to a flat state after being lifted by micro negative pressure and then pressed down by micro positive pressure, and the biological substances in the biological liquid sample can be prevented from being damaged due to the fact that the biological substances are quickly extruded by the film.

The 8 sets of the air pressure supply device 400 provide positive pressure, negative pressure, or normal pressure paths from the first air pressure path to the eighth air pressure path, which respectively actuate the 8 valves 130A to 130H of the micro flow channel chip 100. Each air pressure path is the same, the positive pressure distribution groove 224 and the negative pressure distribution groove 234 respectively provide positive pressure and negative pressure to each first solenoid valve 431A-431H, each first solenoid valve 431A-431H transmits the positive pressure or the negative pressure to the corresponding second solenoid valve 432A-432H, and each second solenoid valve 432A-432H transmits the positive pressure or the negative pressure or the normal pressure to the corresponding valve 130A-130H. Taking the first air pressure path as an example, the first air pressure path is that the positive pressure motor 222 provides positive pressure to the first solenoid valve 431A through the positive pressure air distribution groove 224, the negative pressure motor 232 provides negative pressure to the first solenoid valve 431A through the negative pressure air distribution groove 234, the first solenoid valve 431A controls the positive pressure or the negative pressure to be transmitted to the second solenoid valve 432A, and the second solenoid valve 432A controls the positive pressure or the negative pressure or the normal pressure to be transmitted to the micro channel chip 100, so as to actuate the valve 130A. Since the valves 130A-130H of the micro flow channel chip 100 require a relatively strong air pressure to actuate, the air pressure from the first air pressure path to the eighth air pressure path can provide an air pressure of + -0.1-12 psi to actuate the valves 130A-130H.

In this embodiment, when the air pressure supply device 400 provides negative pressure to the valves 130A-130H of the micro flow channel chip 100, the valves 130A-130H are lifted to open. When the air pressure supply device 400 provides positive pressure to the valves 130A-130H of the micro flow channel chip 100, the valves 130A-130H are pressed down and closed. When the air pressure supply device 400 supplies normal pressure to the valves 130A to 130H of the micro flow channel chip 100, the valves 130A to 130H are in a closed state.

The path of the pressure supply device 400 providing 1 set of negative or normal pressure is a negative pressure path, which is communicated to the collection area 140 of the micro channel chip 100, so that the waste liquid in the collection area 140 is collected in the collection tank 320. The negative pressure path is that the positive pressure motor 222 provides positive pressure to the first solenoid valve 441 through the positive pressure gas distribution groove 224, the negative pressure motor 232 provides negative pressure to the first solenoid valve 441 through the negative pressure gas distribution groove 234, the first solenoid valve 441 provides negative pressure to the second solenoid valve 442, the second solenoid valve 442 controls the negative pressure or the normal pressure to be conveyed to the collecting groove 320, and then conveyed to the collecting region 140 of the micro channel chip 100, so that the waste liquid in the collecting region 140 is collected into the collecting groove 320 through the negative pressure.

In this embodiment, when the air pressure supply device 400 provides negative pressure to the collection region 140 of the microchannel chip 100, the waste liquid in the collection region 140 is collected in the collection tank 320. When the collection region 140 of the microchannel chip 100 is empty of waste liquid or the amount of waste liquid to be removed is not yet sufficient, the air pressure supply means 400 can supply normal pressure to the collection region 140 of the microchannel chip 100.

In this embodiment, each of the first solenoid valves and each of the second solenoid valves is controlled by the controller 350 (shown in fig. 1) to open the positive pressure inlet or the negative pressure inlet or the normal pressure inlet of each of the solenoid valves to deliver micro positive pressure, micro negative pressure, positive pressure, negative pressure or normal pressure to the micro flow channel chip 100.

In this embodiment, in order to conform to the micro flow channel chip 100 of FIG. 2, 1 set of non-operating air pressure paths is reserved for the air pressure supply device 400. When other detection devices are required, the set of air pressure paths can provide positive pressure, negative pressure or normal pressure, the set of air pressure paths provides positive pressure from the positive pressure motor 222 to the first solenoid valve 451 through the positive pressure distribution groove 224, the negative pressure motor 232 provides negative pressure to the first solenoid valve 451 through the negative pressure distribution groove 234, the first solenoid valve 451 delivers the positive pressure or the negative pressure to the second solenoid valve 452, and the second solenoid valve 452 delivers the positive pressure or the negative pressure or the normal pressure to the required position of the detection device.

In this embodiment, the air pressure supply device 400 also includes a magnetic device 330 (shown in FIG. 1) capable of generating a magnetic field to attract the magnetic substance in the micro flow channel chip 100, and a heating device 282 and a fan 340 (shown in FIG. 1) for heating and cooling the micro flow channel chip 100, respectively.

In summary, the present invention provides a novel concept that the air pressure supply device provides micro positive pressure, micro negative pressure, positive pressure, negative pressure and normal pressure to the detection device via three paths, so as to more precisely control the actuation of each component in the detection device and reduce the damage of the detected material. It will be apparent to those skilled in the art that various changes and modifications can be made without departing from the true spirit and scope of the disclosure.

Description of the symbols

10 detection device

100 micro flow channel chip

110 first pump

120: second pump

130A-130H valve

140 collection area

20 air pressure supply device

210: body

212 upper layer

214 lower layer

220 positive pressure supply source

222 positive pressure motor

224 positive pressure gas distribution groove

230 negative pressure supply source

232 negative pressure motor

234 negative pressure gas distribution groove

240 positive pressure fine regulating valve

242 first positive pressure trim valve

244 second positive pressure trim valve

250 negative pressure fine regulating valve

252 first negative pressure trim valve

254 second negative pressure fine adjustment valve

260 first electromagnetic valve group

262. 264, 266, 411, 421, 431A-431H, 441, 451A first solenoid valve

270 second electromagnetic valve group

272. 274, 276, 412, 422, 432A-432H, 442, 452 second solenoid valves

273. 275, 277 air ports

280 bearing table

282 heating device

310 pressure sensor

312 first pressure sensor

314 second pressure sensor

320 collecting groove

330 magnetic device

340 fan

350, a controller.

Claims

1. An air pressure supply device for supplying positive pressure, negative pressure or normal pressure to a micro flow channel chip, wherein the micro flow channel chip includes a first pump, the air pressure supply device comprising:

a body;

a bearing platform arranged on the body and used for bearing the micro-channel chip;

a positive pressure motor arranged on the body for generating the positive pressure;

a negative pressure motor arranged on the body for generating the negative pressure;

the first positive pressure fine adjusting valve is connected with the positive pressure motor and used for precisely adjusting the positive pressure to generate a first micro positive pressure;

the first negative pressure fine adjustment valve is connected with the negative pressure motor and used for precisely adjusting the magnitude of the negative pressure to generate first micro negative pressure;

the first electromagnetic valve is provided with two first inlets and a first outlet, wherein the two first inlets are respectively connected with the first positive pressure fine regulating valve and the first negative pressure fine regulating valve and used for controlling the first micro positive pressure or the first micro negative pressure to pass through; and

the second electromagnetic valve is provided with a second inlet, a first atmosphere port and a second outlet, wherein the second inlet is connected with the first outlet of the first electromagnetic valve and is used for allowing the first micro-positive pressure or the first micro-negative pressure to pass through, the first atmosphere port is used for allowing the normal pressure to pass through, the second outlet is connected with the first pump of the micro-channel chip, and the first micro-positive pressure, the first micro-negative pressure or the normal pressure are provided to the micro-channel chip through the second electromagnetic valve so as to enable the first pump to act.

2. The pneumatic pressure supply device according to claim 1, wherein the micro flow channel chip further comprises a second pump, and the pneumatic pressure supply device further comprises:

the second positive pressure fine adjusting valve is connected with the positive pressure motor and used for precisely adjusting the positive pressure to generate a second micro positive pressure;

the second negative pressure fine adjustment valve is connected with the negative pressure motor and used for precisely adjusting the negative pressure to generate second micro negative pressure;

the second electromagnetic valve is provided with two second inlets and a second outlet, wherein the two second inlets are respectively connected with the second positive pressure fine regulating valve and the second negative pressure fine regulating valve and used for controlling the second micro positive pressure or the second micro negative pressure to pass through; and

and a fourth solenoid valve having a fourth inlet, a second atmosphere port and a fourth outlet, wherein the fourth inlet is connected to the third outlet of the third solenoid valve for allowing the second micro-positive pressure or the second micro-negative pressure to pass through, the second atmosphere port is used for allowing the normal pressure to pass through, the fourth outlet is connected to the second pump of the microchannel chip, and the second micro-positive pressure, the second micro-negative pressure or the normal pressure is provided to the microchannel chip through the fourth solenoid valve, thereby actuating the second pump.

3. The air pressure supply device according to claim 2, further comprising a pressure sensor disposed between the second solenoid valve and the fourth solenoid valve and the micro flow channel chip for sensing the magnitude of the first micro positive pressure, the second micro positive pressure, the first micro negative pressure or the second micro negative pressure.

4. The pneumatic pressure supply device according to claim 2, wherein the micro flow channel chip further comprises a plurality of valves, and the pneumatic pressure supply device further comprises:

the plurality of fifth electromagnetic valves are respectively provided with two fifth inlets and a fifth outlet, wherein the two fifth inlets are respectively connected with the positive pressure motor and the negative pressure motor and used for controlling the positive pressure or the negative pressure to pass through; and

and the sixth electromagnetic valves are respectively connected with the fifth electromagnetic valves, each sixth electromagnetic valve is provided with a sixth inlet, a third atmosphere port and a sixth outlet, wherein the sixth inlet is connected with the fifth outlet of the corresponding fifth electromagnetic valve and used for allowing the positive pressure or the negative pressure to pass through, the third atmosphere port is used for providing the normal pressure, the sixth outlet is connected with one of the valves of the microchannel chip, and the positive pressure, the negative pressure or the normal pressure is provided to the microchannel chip through the sixth electromagnetic valves so as to enable the valves to actuate.

5. The apparatus according to claim 4, further comprising a positive pressure gas distribution tank and a negative pressure gas distribution tank, wherein the positive pressure gas distribution tank is connected to the positive pressure motor for storing positive pressure gas generated by the positive pressure motor and providing the positive pressure gas to the first positive pressure fine adjustment valve, the second positive pressure fine adjustment valve and the fifth solenoid valves, and the negative pressure gas distribution tank is connected to the negative pressure motor for storing vacuum suction generated by the negative pressure motor and providing the vacuum suction to the first negative pressure fine adjustment valve, the second negative pressure fine adjustment valve and the fifth solenoid valves.

6. The air pressure supply device according to claim 5, further comprising a collecting tank, wherein the micro flow channel chip further comprises a collecting region, the collecting tank is disposed between the negative pressure distribution tank and the collecting region of the micro flow channel chip for collecting the waste liquid in the collecting region into the collecting tank via the negative pressure.

7. The air pressure supply device of claim 1, further comprising a magnetic device disposed under the carrier for generating a magnetic field to attract the magnetic substance in the micro flow channel chip.

8. The air pressure supply device of claim 1, further comprising at least one fan disposed on the body, and the susceptor comprises a heating device, wherein the heating device and the at least one fan are used to heat and cool the microchannel chip, respectively.

9. An air pressure supply device for providing air pressure to a detection device, the air pressure supply device comprising:

a body;

the bearing platform is arranged on the body and used for bearing the detection device;

a positive pressure motor arranged on the body for generating positive pressure;

a negative pressure motor arranged on the body for generating negative pressure;

the first electromagnetic valve is provided with two first inlets and a first outlet, wherein the two first inlets are respectively connected with the positive pressure motor and the negative pressure motor and used for controlling the positive pressure or the negative pressure to pass through; and

the second electromagnetic valve is provided with a second inlet, an atmosphere port and a second outlet, wherein the second inlet is connected with the first outlet of the first electromagnetic valve and used for allowing the positive pressure or the negative pressure to pass through, the atmosphere port is used for allowing the normal pressure to pass through, the second outlet is connected with the detection device, and the positive pressure, the negative pressure or the normal pressure is provided to the detection device through the second electromagnetic valve.

10. The air pressure supply device according to claim 9, further comprising:

the positive pressure fine adjustment valve is connected with the positive pressure motor and used for precisely adjusting the positive pressure to generate micro positive pressure;

the negative pressure fine adjustment valve is connected with the negative pressure motor and used for precisely adjusting the negative pressure to generate micro negative pressure;

the third electromagnetic valve is provided with two third inlets and a third outlet, wherein the two third inlets are respectively connected with the positive pressure fine adjustment valve and the negative pressure fine adjustment valve and used for controlling the micro positive pressure or the micro negative pressure to pass through; and

and the fourth electromagnetic valve is provided with a fourth inlet, a second atmosphere port and a fourth outlet, wherein the fourth inlet is connected with the third outlet of the third electromagnetic valve and is used for allowing the micro-positive pressure or the micro-negative pressure to pass through, the second atmosphere port is used for providing the normal pressure to pass through, and the fourth outlet is connected with the detection device and is used for providing the micro-positive pressure, the micro-negative pressure or the normal pressure to the detection device through the fourth electromagnetic valve.

11. The air pressure supply device according to claim 10, further comprising a pressure sensor disposed between the fourth solenoid valve and the detection device for sensing the magnitude of the micro positive pressure or the micro negative pressure.

12. The apparatus according to claim 10, further comprising a positive pressure gas distribution tank and a negative pressure gas distribution tank, wherein the positive pressure gas distribution tank is connected to the positive pressure motor for storing positive pressure gas generated by the positive pressure motor and providing the positive pressure gas to the first solenoid valve and the positive pressure fine adjustment valve, and the negative pressure gas distribution tank is connected to the negative pressure motor for storing vacuum suction generated by the negative pressure motor and providing the vacuum suction to the first solenoid valve and the negative pressure fine adjustment valve.

13. The air pressure supply apparatus according to claim 9, further comprising a collecting tank, wherein the collecting tank is disposed between the negative pressure distribution tank and the detection device for collecting the waste liquid in the detection device into the collecting tank via the negative pressure.

14. The apparatus of claim 9, further comprising a magnetic device disposed under the susceptor for generating a magnetic field to attract the magnetic substance in the detecting device.

15. The air pressure supply apparatus according to claim 9, further comprising at least one fan disposed on the body, and the susceptor comprises a heating device, wherein the heating device and the at least one fan are respectively used for heating and cooling the detecting device.

16. An air pressure supply device for providing air pressure to a detection device, the air pressure supply device comprising:

a body;

the bearing table is arranged on the body and used for bearing the detection device;

the negative pressure fine adjustment valve is connected with the negative pressure motor and used for precisely adjusting the negative pressure to generate micro negative pressure; and

and the electromagnetic valve is provided with two inlets and an outlet, wherein the two inlets are respectively connected with the positive pressure fine adjustment valve and the negative pressure fine adjustment valve and used for controlling the micro positive pressure or the micro negative pressure to pass through, and the outlet is connected with the detection device and used for providing the micro positive pressure or the micro negative pressure to the detection device.