CN216484524U

CN216484524U - Filter integrity tester for preparing non-alcoholic steatohepatitis resisting bulk drug

Info

Publication number: CN216484524U
Application number: CN202123331978.0U
Authority: CN
Inventors: 刘强
Original assignee: Nanjing Huicheng Pharmaceutical Co ltd
Current assignee: Nanjing Huicheng Pharmaceutical Co ltd
Priority date: 2021-12-28
Filing date: 2021-12-28
Publication date: 2022-05-10
Anticipated expiration: 2031-12-28

Abstract

The utility model discloses a filter integrality tester for preparing a non-alcoholic steatohepatitis resisting raw material medicine, which relates to the technical field of non-alcoholic steatohepatitis resisting raw material medicine preparation equipment and comprises a detection box and a control panel, wherein the detection box detects the integrality of a filter through a built-in detection component, the control panel is electrically connected with the detection component and is used for controlling the working state of the detection component, the integrality tester also comprises a clamping mechanism used for clamping a filter piece to be detected, the clamping mechanism comprises a vertical plate, an air cylinder, an upper gland and a lower gland, the vertical plate is vertically fixed on the detection box through a base, the air cylinder is vertically fixed at the top position of the vertical plate through a fixing seat, the filter element can be clamped and fixed through the clamping mechanism, and the filter disc can be clamped and fixed, so that the tester not only can carry out integrality test on the filter element, but also can carry out integrality test on the filter disc, the applicability of the device is improved, and meanwhile, the detector is high in detection efficiency, better in sealing effect and smaller in detection error.

Description

Filter integrity tester for preparing non-alcoholic steatohepatitis resisting bulk drug

Technical Field

The utility model relates to an anti non-alcoholic steatohepatitis bulk drug preparation equipment technical field, concretely relates to anti non-alcoholic steatohepatitis bulk drug is filter integrality tester for preparation.

Background

Non-alcoholic steatohepatitis, also known as metabolic steatohepatitis, is a clinical syndrome with pathological changes similar to alcoholic hepatitis but without history of excessive drinking, and is better to be developed in middle-aged and particularly overweight and obese individuals. The non-alcoholic steatohepatitis is closely related to metabolic disorders such as obesity, insulin resistance, type 2 diabetes mellitus, hyperlipidemia and the like, and is mainly characterized in that hepatic cell bullous steatosis is accompanied with hepatic cell injury and inflammation, and a serious patient can develop liver cirrhosis. The bulk drug for resisting the nonalcoholic steatohepatitis is used for preparing a finished drug for resisting the nonalcoholic steatohepatitis, the bulk drug for resisting the nonalcoholic steatohepatitis needs to be subjected to multiple filtration of a filter in the processing process, and the integrity of the filter needs to be detected due to high filtration requirements.

Although the existing filter integrity tester can detect the integrity of the filter, certain defects still exist in the using process, the existing filter integrity tester can only detect a filter disc or a filter element, has single detection function, and cannot be suitable for various filtering environments for processing the anti-nonalcoholic fatty hepatitis raw material. Therefore, the filter integrity tester for preparing the non-alcoholic fatty hepatitis resisting raw material medicine is provided for overcoming the defects of the prior art.

Disclosure of Invention

In order to overcome not enough among the prior art, the utility model provides an anti non-alcoholic fatty hepatitis bulk drug preparation is with filter integrality tester, it can be suitable for the filtration piece of different models, and the suitability is stronger.

In order to achieve the purpose, the utility model discloses a filter integrality tester for preparing anti-non-alcoholic fatty hepatitis bulk drug, including detection case and control panel, the detection case detects filter integrality through built-in detection subassembly, control panel electric connection detection subassembly is used for controlling the operating condition of detection subassembly, the integrality tester still includes the fixture for the centre gripping to detect the filter piece, the fixture includes riser, cylinder, upper gland and lower gland, the riser passes through the base vertical fixation on the detection case, the cylinder passes through the fixing base vertical fixation at the riser top position;

the telescopic rod of the cylinder is connected with the upper gland through the connecting seat, wherein a discharge nozzle is arranged on the upper gland in a penetrating manner, one end of the discharge nozzle is connected with the feed end of the detection box through a guide pipe, the other end of the discharge nozzle extends to the inner cavity of the upper gland, a first clamping groove is arranged along the edge of the inner cavity of the upper gland in an annular structure, and a first sealing gasket is arranged in the first clamping groove in a cushioning manner;

the lower gland is fixed above the base through a supporting table, a groove is concavely arranged on the upper end face of the lower gland, a mounting groove is concavely arranged in the center of the groove, the mounting groove is communicated with the discharging nozzle through a locking groove, the bottom end of the discharging nozzle is connected with the feeding end of the detection box through a conveying pipe, a second clamping groove which is of an annular structure is further concavely arranged on the groove by taking the mounting groove as the center, a second sealing gasket is arranged in the second clamping groove in a cushioning mode, and the second clamping groove is corresponding to the first clamping groove in position and is matched with the first clamping groove in specification.

Preferably, the riser lateral wall sets up the tank chain, and riser, other end connection connecting seat are connected to tank chain one end to pass the pipe in the tank chain.

Preferably, set up a plurality of spouts perpendicularly along the riser lateral wall, the back lateral wall fixed connection slide of connecting seat, the protruding slider of establishing a plurality of and corresponding with the spout of the back lateral wall of slide, the slider block slides from top to bottom in the spout and along the spout.

Preferably, the mounting groove specification and filter core specification looks adaptation set up the third along the edge of the bottom of mounting groove inner chamber and seal up the pad, the plug specification looks adaptation of locking groove specification and filter core bottom to the locking inslot lateral wall is the concave seal groove that is used for the upper seal circle of block plug of establishing of annular structure.

Preferably, the diameter of lower gland is greater than the diameter of last gland, sets up the fourth sealed pad that is annular structure through solid fixed ring block in the recess of lower gland, and the lower edge position of fourth sealed pad and last gland is corresponding, specification looks adaptation.

The utility model discloses following beneficial effect has:

the utility model provides an anti non-alcoholic steatohepatitis bulk drug preparation is with filter integrality tester not only can be fixed with the filter core centre gripping through fixture, but also can the fixed filter element of centre gripping for the tester not only can carry out the integrality test to the filter core, but also can carry out the integrality test to the filter element, improves the suitability of device, and this detector detection efficiency is high simultaneously, and sealed effect is better, and detection error is littleer.

Drawings

The invention will be further described and illustrated with reference to the accompanying drawings.

Fig. 1 is a schematic view of the overall structure of a filter integrity tester for preparing a non-alcoholic steatohepatitis-resistant raw material drug according to a preferred embodiment of the present invention.

FIG. 2 is a schematic view showing the structure of a holding mechanism of the filter for preparing the anti-nonalcoholic fatty hepatitis drug substance shown in FIG. 1.

Fig. 3 is a schematic view of the upper gland structure of the clamping mechanism of fig. 2.

Fig. 4 is a schematic view of a lower press cover of the clamping mechanism of fig. 2.

Reference numerals: 1. a detection box; 2. a clamping mechanism; 21. a vertical plate; 22. a cylinder; 23. a gland is arranged; 24. a lower gland; 25. a base; 26. a tank chain; 27. a fixed seat; 28. a connecting seat; 29. a slide base; 210. a chute; 211. a support table; 212. a discharging nozzle; 213. a first card slot; 214. a first gasket; 215. mounting grooves; 216. a locking groove; 217. a discharging nozzle; 218. a second gasket; 219. a fixing ring; 220. a third gasket; 221. a second card slot; 222. a fourth gasket; 3. a control panel.

Detailed Description

The technical solution of the present invention will be more clearly and completely explained by the description of the preferred embodiments of the present invention with reference to the accompanying drawings.

Examples

As shown in figure 1, the utility model discloses an anti non-alcoholic fatty hepatitis bulk drug preparation is with filter integrality tester, including detection case 1 and control panel 3, detection case 1 detects filter integrality through built-in determine module, and 3 electric connection determine module of control panel are used for controlling determine module's operating condition.

In this embodiment, the detection module mainly performs integrity test by using a bubble point method test principle, detects the corresponding pressure when the wetting liquid is pressed out of the largest hole of the filter membrane, and the control panel 3 is mainly used for inputting parameters and controlling the working state of the detection module.

As shown in fig. 1 and fig. 2, the integrity tester further includes a clamping mechanism 2 for clamping a filter to be tested, the clamping mechanism 2 includes a vertical plate 21, an air cylinder 22, an upper pressing cover 23 and a lower pressing cover 24, the vertical plate 21 is vertically fixed on the testing box 1 through a base 25, and the air cylinder 22 is vertically fixed at the top of the vertical plate 21 through a fixing seat 27.

In this embodiment, the clamping mechanism 2 is mainly used for clamping a filter element or a filter disc, when the detection is performed, the entering liquid is pressed out of the filter hole through pressure, and the position of the upper pressing cover 23 can be adjusted up and down through the air cylinder 22, so that the filter cartridge of the filter element can be clamped and fixed between the upper pressing cover 23 and the lower pressing cover 24, and the position of the upper pressing cover 23 can also be continuously adjusted down, so that the filter disc can be clamped and fixed between the upper pressing cover 23 and the lower pressing cover 24.

As shown in fig. 3 and 4, the telescopic rod of the cylinder 22 is connected to the upper gland 23 through the connecting seat 28, wherein the upper gland 23 is provided with a discharging nozzle 217212, one end of the discharging nozzle 217212 is connected to the feeding end of the detection box 1 through a conduit, and the other end extends to the inner cavity of the upper gland 23, a first clamping groove 213 is provided along the edge of the inner cavity of the upper gland 23 in an annular structure, a first sealing gasket 214 ring is arranged in the first clamping groove 213, the lower gland 24 is fixed above the base 25 through a supporting platform 211, a groove is concavely provided on the upper end surface of the lower gland 24, a mounting groove 215 is concavely provided at the center position of the groove, the mounting groove 215 is communicated with the discharging nozzle 217212 through a locking groove 216, the bottom end of the discharging nozzle 217212 is connected to the feeding end of the detection box 1 through a conveying pipe, a second clamping groove 221 in an annular structure is concavely provided on the groove with the mounting groove 215 as the center, a second sealing gasket 218 ring is arranged in the second clamping groove 221, the clamping groove 221 corresponds to the first clamping groove 213, The specification is adaptive.

In this embodiment, the discharging nozzle 217212 is communicated with the feeding end through a conduit, when the integrity of the filter element is detected, the bottom of the filter element is firstly clamped and fixed in the mounting groove 215 of the lower gland 24, then the top end of the filter cartridge is clamped in the first clamping groove 213, the bottom end of the filter cartridge is clamped in the second clamping groove 221, the wet liquid at the feeding end enters the inner cavity of the upper gland 23 through the discharging nozzle 217212 under the action of pressure, and the liquid is filtered by the filter element and enters the detection box 1 again through the discharging nozzle 217212.

As the utility model discloses a technical optimization scheme, the riser lateral wall sets up tank chain 26, and riser 21, other end connection connecting seat 28 are connected to tank chain 26 one end to pass the pipe in the tank chain 26.

Through adopting above-mentioned technical scheme to can utilize tank chain 26 to carry on spacingly to the pipe, prevent that the pipe from twineing, folding influence liquid supply effect at removal in-process.

As a technical optimization scheme of the utility model, set up a plurality of spouts 210 perpendicularly along riser 21 lateral wall, the back lateral wall fixed connection slide 29 of connecting seat 28, the protruding slider of establishing a plurality of and spout 210 correspondences of the back lateral wall of slide 29, the slider block slides from top to bottom in spout 210 and along spout 210.

By adopting the technical scheme, the sliding seat 29 can be utilized to vertically slide along the sliding groove 210, the upper pressing cover 23 can be ensured to move along a fixed track when moving up and down, and the accuracy of the upper pressing cover 23 in moving is improved.

As a technical optimization scheme, mounting groove 215 specification and filter core specification looks adaptation set up the sealed pad 220 of third along the edge of the bottom of mounting groove 215 inner chamber, the plug specification looks adaptation of locking groove 216 specification and filter core bottom to locking groove 216 inside wall is the concave seal groove of establishing the sealing washer on the block plug of annular structure.

Through adopting above-mentioned technical scheme to can utilize the third to seal up the sealed filter core bottom and mounting groove 215 of filling up 220, can utilize the seal groove to come the sealed sealing washer on the sealed filter core of block simultaneously, guarantee that the filter core can not be fixed firm stable, improve the leakproofness of filter core bottom moreover.

As a technical optimization scheme of the utility model, the diameter of lower gland 24 is greater than the diameter of last gland 23, and the fourth sealed pad 222 that is the loop configuration is set up through solid fixed ring 219 block in the recess of lower gland, and the fourth sealed pad 222 is corresponding, specification looks adaptation with the lower edge position of last gland 23.

Through adopting above-mentioned technical scheme, when detecting the filter element integrality, place the filter element level on fourth sealed 222, cylinder 22 drive upper gland 23 moves down for upper gland 23's bottom can the pressfitting fix on the filter element, and the moist liquid of feed end enters into the inner chamber of upper gland 23 under the pressure effect by ejection of compact mouth 217212, and liquid filters through the filter chip and enters into in detection case 1 again by ejection of compact mouth 217212.

The above detailed description merely describes the preferred embodiments of the present invention and does not limit the scope of the present invention. Without departing from the design concept and spirit scope of the present invention, the ordinary skilled in the art should belong to the protection scope of the present invention according to the present invention provides the text description and drawings to the various modifications, replacements and improvements made by the technical solution of the present invention. The scope of protection of the present invention is determined by the claims.

Claims

1. The integrity tester for the filter for preparing the non-alcoholic steatohepatitis resisting raw material medicine comprises a detection box and a control panel, wherein the detection box detects the integrity of the filter through a built-in detection assembly, and the control panel is electrically connected with the detection assembly and used for controlling the working state of the detection assembly;

the telescopic rod of the air cylinder is connected with the upper gland through the connecting seat, wherein a discharge nozzle is arranged on the upper gland in a penetrating manner, one end of the discharge nozzle is connected with the feeding end of the detection box through a guide pipe, the other end of the discharge nozzle extends to the inner cavity of the upper gland, a first clamping groove is arranged along the edge of the inner cavity of the upper gland in an annular structure, and a first sealing gasket is arranged in the first clamping groove in a cushioning manner;

the utility model discloses a gland, including a base, a lower gland, a supporting bench, the gland passes through the brace table to be fixed in the base top down, the concave recess of establishing of up end of gland down, the central point of recess puts the concave mounting groove of establishing, the mounting groove passes through locking groove intercommunication ejection of compact mouth, the feed end of conveyer pipe connection detection case is passed through to the bottom of ejection of compact mouth, use the mounting groove to still set up the second draw-in groove that is loop configuration as the center concave on the recess, second seal ring is established to the pad in the second draw-in groove, second draw-in groove and first draw-in groove position are corresponding, specification looks adaptation.

2. The tester for testing the integrity of the filter for preparing the bulk drug for resisting nonalcoholic fatty hepatitis according to claim 1, wherein a tank chain is arranged on the side wall of the vertical plate, one end of the tank chain is connected with the vertical plate, the other end of the tank chain is connected with the connecting seat, and a guide pipe passes through the tank chain.

3. The tester for testing the integrity of the filter for preparing the non-alcoholic steatohepatitis raw material drug according to claim 2, wherein a plurality of sliding grooves are vertically arranged along the side wall of the vertical plate, the rear side wall of the connecting seat is fixedly connected with a sliding seat, a plurality of sliding blocks corresponding to the sliding grooves are convexly arranged on the rear side wall of the sliding seat, and the sliding blocks are clamped in the sliding grooves and slide up and down along the sliding grooves.

4. The tester for testing the integrity of the filter for preparing the non-alcoholic steatohepatitis raw material drug as claimed in claim 1, wherein the specification of the installation groove is adapted to the specification of the filter element, a third sealing gasket is arranged along the edge of the bottom of the inner cavity of the installation groove, the specification of the locking groove is adapted to the specification of the plug at the bottom of the filter element, and the inner side wall of the locking groove is in an annular structure and is concavely provided with a sealing groove for clamping the upper sealing ring of the plug.

5. The filter integrity tester for preparing a non-alcoholic steatohepatitis raw material drug according to claim 1, wherein the diameter of the lower gland is larger than that of the upper gland, a fourth sealing gasket in an annular structure is arranged in a groove of the lower gland in a clamping manner through a fixing ring, and the fourth sealing gasket corresponds to the lower edge of the upper gland in position and is adaptive to the specification.