CN216169306U

CN216169306U - Medical catheter and medical kit

Info

Publication number: CN216169306U
Application number: CN202122554193.3U
Authority: CN
Inventors: 高凌岳; 徐茜; 王金耀; 朱清
Original assignee: Shanghai Tuomai Medical Technology Co ltd
Current assignee: Shanghai Tuomai Medical Technology Co ltd
Priority date: 2021-10-22
Filing date: 2021-10-22
Publication date: 2022-04-05
Anticipated expiration: 2031-10-22

Abstract

The utility model provides a medical catheter and a medical kit, wherein the medical kit comprises the medical catheter and an embolic agent, the medical catheter is used for being partially inserted into a target lumen and used for conveying the embolic agent to a preset position in the target lumen and blocking the target lumen; the medical catheter comprises a catheter body and an auxiliary unit, wherein the auxiliary unit is sleeved on the outer surface of the distal end of the catheter body and is configured to be capable of contracting or expanding along the radial direction of the catheter body, when the auxiliary unit expands, the auxiliary unit is abutted with the cavity wall of the target cavity and keeps the distal end of the catheter body in the target cavity in a preset posture, for example, a central posture, so that the embolic agent can be conveyed along the axis of the target cavity and uniformly blocks the target cavity to avoid accumulation.

Description

Medical catheter and medical kit

Technical Field

The utility model relates to the technical field of medical instruments, in particular to a medical catheter and a medical kit.

Background

Transcatheter Arterial Chemoembolization (TACE) is an important method for the clinical treatment of hepatocellular carcinoma (HCC). TACE blocks the blood supply of tumor by injecting solid embolus into blood supply artery of embolized tumor, so as to make tumor be ischemic and anoxic, and further attain the goal of inhibiting tumor growth and promoting tumor cell necrosis and apoptosis.

During TACE surgery, a physician usually punctures the femoral artery, inserts a contrast catheter from the puncture port, runs in the reverse direction along the inferior artery and reaches the hepatic artery through the celiac trunk artery, performs DSA angiography, and observes the location of the tumor, i.e., the distribution of the blood supply vessels of the tumor. After the blood vessel path is determined, the micro catheter is selected into a blood supply target artery of the tumor through the cooperation of the micro guide wire and the micro catheter, then the micro guide wire is withdrawn, and the embolic agent is injected to a preset position of the blood supply target artery along the micro catheter.

When TACE operation is carried out in the prior art, the problem that easily appears is that if the external diameter of microcatheter is less than the diameter of blood vessel, the distal end of microcatheter often pastes and leans on the vascular wall, leads to solid embolus can not carry along the blood vessel center, leads to solid embolus can not seal up the blood vessel evenly, piles up at certain one side of blood vessel even, in addition, when the transport speed of solid embolus was too fast, solid embolus still takes place palirrhea easily, drifts into non-target blood vessel even, causes the necrosis of healthy tissue.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a medical catheter and a medical kit, which can enable an embolic agent to be conveyed along the center of a blood vessel when the embolic agent is conveyed by the medical catheter, so that solid emboli can uniformly block the blood vessel.

In order to achieve the above object, the present invention provides a medical catheter, which comprises a catheter body and an auxiliary unit, wherein the catheter body has an inner cavity extending axially through the catheter body, and a flow guide section is formed at the distal end of the catheter body, and a flow guide hole communicated with the inner cavity is formed on the flow guide section; the auxiliary unit covers the flow guide section, and two axial ends of the auxiliary unit are respectively connected with the outer wall of the conduit body in a sealing manner;

the medical catheter is configured such that when a dilator flows from the diversion hole into between the auxiliary unit and the outer wall of the catheter body, the auxiliary unit expands in the radial direction of the catheter body, and a containing cavity is formed between the auxiliary unit and the outer wall of the catheter body to contain the dilator; when the expanding agent is discharged from the containing cavity through the diversion hole, the auxiliary unit is contracted along the radial direction of the catheter body.

Optionally, the auxiliary unit comprises a membrane material.

Optionally, the number of the flow guide holes is multiple, and the flow guide holes are uniformly distributed on the flow guide section along the circumferential direction and the axial direction of the conduit body.

Optionally, the lumen of the catheter body is for delivery of an embolic agent comprising a dispersion and a solid embolic material, the dispersion constituting the dilator; the aperture of the diversion hole is smaller than the grain diameter of the solid embolus.

Optionally, the medical catheter further comprises a visualization element for displaying the position of the auxiliary unit.

Optionally, the number of the developing elements is two, and the two developing elements are respectively located at two ends of the auxiliary unit in the axial direction.

Optionally, the medical catheter further comprises a connector connected to the proximal end of the catheter body.

To achieve the above object, the present invention also provides a medical kit comprising the medical catheter according to any one of the preceding claims and an embolic agent; the lumen is for delivery of the embolic agent, and the embolic agent comprises a dispersion and a solid embolic material, the solid embolic material being dispersed in the dispersion; the dispersion liquid partially flows from the diversion holes into a space between the auxiliary unit and the outer wall of the catheter body, so that the auxiliary unit expands along the radial direction of the catheter body, and a containing cavity is formed between the auxiliary unit and the outer wall of the catheter body to contain the expanding agent; when the expanding agent is discharged from the containing cavity through the diversion hole, the auxiliary unit is contracted along the radial direction of the catheter body.

Optionally, the solid embolus comprises a carrier and a drug.

Compared with the prior art, the medical catheter and the medical kit have the advantages that:

the medical catheter comprises a catheter body and an auxiliary unit, wherein the catheter body is provided with an inner cavity which axially extends through the catheter body, a flow guide section is formed at the far end of the catheter body, and a flow guide hole communicated with the inner cavity is formed in the flow guide section; the auxiliary unit covers the flow guide section, and two axial ends of the auxiliary unit are respectively connected with the outer wall of the conduit body in a sealing manner; the medical catheter is configured to apply a force outwards along the radial direction of the catheter body to the auxiliary body from the flow guide hole when a dilator flows along the inner cavity under the action of an external force, so that the membrane expands along the radial direction and stores elastic potential energy, and a containing cavity is formed between the membrane and the outer wall of the flow guide section and contains the dilator; when the external force is cancelled, the auxiliary unit releases the elastic potential energy, restores the deformation and enables the expanding agent to be discharged out of the accommodating cavity from the flow guide hole. The medical catheter is used for implanting a target lumen such as a blood supply artery of a tumor (hereinafter referred to as a target blood vessel) and delivering an embolic agent, and when the auxiliary unit is in an expanded state, the auxiliary unit can be abutted with the wall of the target lumen so that the medical catheter is positioned in the target lumen in a predetermined posture, which is usually a centering posture, in the sense that the axis of the distal end of the catheter body coincides with the axis of the target blood vessel, which has the advantage that the embolic agent can be delivered along the center of the blood vessel, so that the solid embolic agent can uniformly occlude the target blood vessel and avoid accumulating on one side of the target blood vessel. Meanwhile, the medical catheter has a smaller outer diameter, and the distal end of the medical catheter is easier to convey to a target blood vessel.

Drawings

The drawings are included to provide a better understanding of the utility model and are not to be construed as unduly limiting the utility model. Wherein:

FIG. 1 is a schematic view of the overall construction of a medical catheter according to an embodiment of the present invention;

FIG. 2 is a schematic view of the distal end of a medical catheter in accordance with one embodiment of the present invention, with the visualization element not shown;

FIG. 3 is a schematic view of the distal end of a medical catheter in accordance with an embodiment of the present invention, with the auxiliary structure unexpanded;

FIG. 4 is a schematic view of a distal end of a medical catheter in accordance with an embodiment of the utility model, with an auxiliary structure expanded.

[ reference numerals are described below ]:

100-medical catheter, 110-catheter body, 111-guide section, 112-guide hole, 120-auxiliary unit, 130-developing element, 140-connector, 150-auxiliary catheter body and 101-containing cavity.

Detailed Description

The embodiments of the present invention are described below with reference to specific embodiments, and other advantages and effects of the present invention will be easily understood by those skilled in the art from the disclosure of the present specification. The utility model is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present invention. It should be noted that the drawings provided in the present embodiment are only for illustrating the basic idea of the present invention, and the components related to the present invention are only shown in the drawings rather than drawn according to the number, shape and size of the components in actual implementation, and the type, quantity and proportion of the components in actual implementation may be changed freely, and the layout of the components may be more complicated.

Furthermore, each of the embodiments described below has one or more technical features, and thus, the use of the technical features of any one embodiment does not necessarily mean that all of the technical features of any one embodiment are implemented at the same time or that only some or all of the technical features of different embodiments are implemented separately. In other words, those skilled in the art can selectively implement some or all of the features of any embodiment or combinations of some or all of the features of multiple embodiments according to the disclosure of the present invention and according to design specifications or implementation requirements, thereby increasing the flexibility in implementing the utility model.

As used in this specification, the singular forms "a", "an" and "the" include plural referents, and the plural forms "a plurality" includes more than two referents unless the content clearly dictates otherwise. As used in this specification, the term "or" is generally employed in its sense including "and/or" unless the content clearly dictates otherwise, and the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either fixedly connected, detachably connected, or integrally connected. Either mechanically or electrically. Either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

Herein, the terms "proximal" and "distal" are relative orientations, relative positions, and directions of elements or actions with respect to each other from the perspective of a clinician using a medical device, and although "proximal" and "distal" are not intended to be limiting, the term "proximal" generally refers to the end of the medical device that is closer to the clinician during normal operation, and the term "distal" generally refers to the end of the medical device that is first introduced into a patient.

To further clarify the objects, advantages and features of the present invention, a more particular description of the utility model will be rendered by reference to the appended drawings. It is to be noted that the drawings are in a very simplified form and are not to precise scale, which is merely for the purpose of facilitating and distinctly claiming the embodiments of the present invention. The same or similar reference numbers in the drawings identify the same or similar elements.

Fig. 1 shows an overall structural diagram of a medical catheter 100 according to an embodiment of the present invention, and fig. 2 to 4 show structural diagrams of a distal end of the medical catheter 100.

Referring to fig. 1-4, the medical catheter 100 is for partial insertion into a target lumen. The medical catheter 100 includes a catheter body 110 and an auxiliary unit 120. The catheter body 110 has a lumen extending therethrough in an axial direction thereof. The auxiliary unit 120 is fitted over the outer surface of the distal end of the catheter body 110, the auxiliary unit 120 is configured to be contracted or expanded in the radial direction of the catheter body 110, and when the auxiliary unit 120 is expanded, the auxiliary unit 120 abuts against the wall of the target lumen and holds the distal end of the catheter body 110 in the target lumen in a predetermined posture. The predetermined posture is a centered posture, i.e., the axis of the distal end of the catheter body 110 coincides with the axis of the target lumen.

The medical catheter 100 can be used for constructing a delivery channel of an embolic agent in a TACE operation, that is, when the medical catheter 100 is used for TACE operation, the medical catheter 100 is partially inserted into a blood supply artery of a tumor (the blood supply artery may be referred to as a target blood vessel, which is the aforementioned target lumen), and an operator delivers the embolic agent to a predetermined position of the target blood vessel through the inner lumen of the catheter body 110 and blocks the target blood vessel to block the blood supply of the tumor. It will be appreciated that the embolic agent comprises a dispersion and a solid embolic material dispersed in the dispersion, the solid embolic material being used to occlude the target blood vessel. Also, the medical catheter 100 may be used in other procedures requiring occlusion of a target lumen, which is determined according to actual conditions, and only TACE procedure is described herein as an example. During operation, even if the outer diameter of the distal end of the catheter body 110 is smaller than the diameter of the target vessel, the catheter body 110 can be supported by the radial expansion of the auxiliary unit 120, and the distal end of the catheter body 110 is prevented from abutting against the local vessel wall, so that the embolic agent can be delivered along the axis of the target vessel, in other words, the solid embolic material can be delivered along the axis of the target vessel, thereby uniformly occluding the target vessel and preventing accumulation in a certain part of the target vessel.

In a non-limiting embodiment, referring to fig. 2 to 4, the distal end of the catheter body 110 is formed with a flow guiding section 111, the flow guiding section 111 is provided with a flow guiding hole 112 communicating with the inner cavity, and the diameter of the flow guiding hole 112 is smaller than the particle size of the solid embolus. The auxiliary unit 120 covers the flow guide section 111, and two axial ends of the auxiliary unit 120 are respectively connected with the outer wall of the catheter body 110 in a sealing manner. Alternatively, the auxiliary unit 120 is mainly composed of a film material having elasticity.

During the delivery of the medical catheter 100, the inner wall of the membrane material abuts the outer wall of the catheter body 110. When the operator injects an embolic agent into the lumen of the catheter body 110 at the proximal end of the catheter body 110 through a pressure mechanism, such as a syringe, after the distal end of the catheter body 110 reaches a predetermined position of a target blood vessel, the embolic agent continuously flows distally in the axial direction of the catheter body 110 under the external force provided by the pressure mechanism. When the embolic agent reaches the diversion section 111, the dispersion of the embolic agent partially applies a force radially outward of the catheter body 110 from the diversion holes 112 to the membrane material, so that the membrane material expands radially outward and stores elastic potential energy, and a containing cavity 101 is formed between the membrane material and the outer wall of the diversion section 111 to contain the dispersion flowing in from the diversion holes 112, and the solid component (i.e. solid embolus) and another part of the dispersion of the embolic agent flow out from the distal end of the catheter body 110 to reach a predetermined position of a target blood vessel. That is, the dispersion constitutes an expanding agent, and a force is continuously applied to the membrane material to continuously expand the membrane material until the membrane material abuts against the vessel wall of the target vessel, thereby preventing backflow of the embolic agent flowing into the predetermined position. When the operator confirms that the solid emboli in the infused embolic agent has occluded the target vessel, the injection of the embolic agent may be stopped and the pressure mechanism no longer provides the external force, in which case the membrane releases the elastic potential energy and compresses the dilator to cause the dilator to exit the containment chamber 101 from the diversion aperture 112. It will be appreciated that during expulsion of the dilator, the receiving cavity 101 gradually decreases until the membrane again abuts the outer wall of the guide section 111, whereupon the membrane returns to its shape, after which the medical catheter 100 can be withdrawn from the body. In this embodiment, when the dispersion of the embolic agent is directly applied with a force to the membrane through the guiding holes 112, the membrane is radially expanded without introducing an additional dilator or providing an additional fluid channel, which not only simplifies the use method, but also reduces the outer diameter of the medical catheter 100, so that the distal end of the medical catheter 100 can enter into smaller blood vessels, and simultaneously reduces the resistance of the medical catheter 100 during the transportation and withdrawal process.

Further, the number of the guide holes 112 is plural, and the plurality of guide holes 112 are uniformly distributed on the guide section 111 along the circumferential direction and the axial direction of the catheter body 110. With this arrangement, on the one hand, the expanding speed of the auxiliary unit 120 can be increased, and on the other hand, the auxiliary unit 120 can be expanded uniformly in the circumferential direction of the catheter body 110, so as to ensure that the auxiliary unit 120 is still coaxial with the catheter body 110 after being expanded, and further ensure that the distal end of the catheter body 110 can be kept centered in the target blood vessel. In other implementations, the plurality of flow guide holes 112 may also be arranged alternately in the circumferential direction and in the axial direction.

In addition, the material of the film and the shape of the flow guide holes 112 are not particularly limited in the embodiments of the present invention. The specific type of the film material can be determined according to the magnitude of the external force provided by the pressure mechanism, and the film material can be a polymer film, such as a TPU thermoplastic film, a polytetrafluoroethylene film and the like, and can also be a metal film. The shape of the diversion holes 112 may be at least one of circular, square, diamond, oval, polygonal, and irregular.

In an alternative embodiment, the auxiliary unit 120 may include a plurality of pre-shaped high-elasticity support rods (not shown). In detail, the support rods can be pre-shaped into an arc, the support rods are arranged around the catheter body, the distal ends of the support rods are fixedly connected to the catheter body after being folded, the proximal ends of the support rods are connected through a connecting ring after being folded, and the connecting ring is movably sleeved on the catheter body. Meanwhile, the medical catheter also comprises a pushing pipe, the pushing pipe is arranged on the outer surface of the catheter body and is configured to be capable of generating axial relative movement with the catheter body, and the distal end of the pushing pipe is connected with the connecting ring. Thus, when the pushing tube drives the proximal end of the supporting rod to move in the direction from the distal end to the proximal end, the pushing tube applies a pulling force to the supporting rod so that the supporting rod is straightened, and thus the auxiliary unit contracts in the radial direction. The support rods may be fabricated from a shape memory alloy, such as nitinol.

Further, as shown in fig. 3 and 4, the medical catheter 100 further includes a visualization element 130, wherein the visualization element 130 is used for displaying the position of the auxiliary unit 120, and is used for assisting in determining whether the distal end of the catheter body 110 reaches a predetermined position of the target blood vessel during the delivery of the medical catheter 100, and determining whether the catheter body 110 and the auxiliary unit 120 are displaced during the infusion of the embolic agent. Alternatively, the number of the developing members 130 is two, and the two developing members 130 are respectively disposed at both ends of the auxiliary unit 120 in the axial direction. It is to be understood that each of the developing units 130 may be connected to only the auxiliary unit 120, only the catheter body 110, or both the auxiliary unit 120 and the catheter body 110. Alternatively, the developing member may be provided on the auxiliary unit (not shown in the drawings).

In addition, the medical catheter 100 further comprises a connector 140 and an auxiliary tube 150, wherein the connector 140 is connected to the proximal end of the catheter body 110 and is used for connecting with an external pressure mechanism. The auxiliary tube 150 covers the proximal outer surface of the catheter body 110 and is also connected to the connector 140, which can play a role of buffering to reduce stress concentration at the connection between the catheter body 110 and the connector 140.

Further, the embodiment of the present invention also provides a medical kit, which includes the medical catheter 100 and the embolic agent.

As previously mentioned, the embolic agent comprises a dispersion and a solid embolic material dispersed in the dispersion. In one embodiment of the present invention, the dispersion may include a contrast agent and saline. The solid embolus can be at least one of microspheres, gelatin sponge and spring embolus. Further, the solid embolus can comprise a carrier and a drug, wherein the carrier can be any suitable drug carrier, the drug can be an anti-tumor drug, such as adriamycin, epirubicin, irinotecan, vandetanib and the like, and the solid embolus can also continuously and slowly release the anti-tumor drug to improve the treatment effect when blocking the target blood vessel.

Although the present invention is disclosed above, it is not limited thereto. Various modifications and alterations of this invention may be made by those skilled in the art without departing from the spirit and scope of this invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims

1. The medical catheter is characterized by comprising a catheter body and an auxiliary unit, wherein the catheter body is provided with an inner cavity which axially extends through the catheter body, a flow guide section is formed at the far end of the catheter body, and a flow guide hole communicated with the inner cavity is formed in the flow guide section; the auxiliary unit covers the flow guide section, and two axial ends of the auxiliary unit are respectively connected with the outer wall of the conduit body in a sealing manner;

2. The medical catheter of claim 1, wherein the auxiliary unit comprises a membrane.

3. The medical catheter as claimed in claim 1, wherein the number of the guiding holes is plural, and the guiding holes are uniformly distributed on the guiding section along the circumferential direction and the axial direction of the catheter body.

4. The medical catheter of claim 1, wherein the lumen of the catheter body is for delivery of an embolic agent comprising a dispersion and a solid embolic material, the dispersion constituting the dilator; the aperture of the diversion hole is smaller than the grain diameter of the solid embolus.

5. The medical catheter of claim 1, further comprising a visualization element for displaying the location of the auxiliary unit.

6. The medical catheter according to claim 5, wherein the number of the developing members is two, and the two developing members are respectively located at both axial ends of the auxiliary unit.

7. The medical catheter of claim 1, further comprising a connector attached to the proximal end of the catheter body.

8. A medical kit comprising the medical catheter of any one of claims 1-7 and an embolic agent; the lumen is for delivery of the embolic agent, and the embolic agent comprises a dispersion and a solid embolic material, the solid embolic material being dispersed in the dispersion; the dispersion liquid partially flows from the diversion holes into a space between the auxiliary unit and the outer wall of the catheter body, so that the auxiliary unit expands along the radial direction of the catheter body, and a containing cavity is formed between the auxiliary unit and the outer wall of the catheter body to contain the expanding agent; when the expanding agent is discharged from the containing cavity through the diversion hole, the auxiliary unit is contracted along the radial direction of the catheter body.

9. The medical kit of claim 8, wherein the solid embolus comprises a carrier and a drug.