CN111529045B - Blood flow uninterrupted cryoablation system and cryoablation method - Google Patents
Blood flow uninterrupted cryoablation system and cryoablation method Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/481—Diagnostic techniques involving the use of contrast agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
- A61B6/504—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of blood vessels, e.g. by angiography
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
- A61B2018/0022—Balloons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00351—Heart
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0212—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
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Abstract
The invention relates to an uninterrupted blood flow cryoablation system, which comprises a balloon catheter, a stent catheter and a guide wire, wherein the balloon catheter is connected with the stent catheter through the guide wire; the balloon catheter comprises a special-shaped balloon, a catheter, an injection joint and a handle which are sequentially connected, wherein three inner cavities in the special-shaped balloon are respectively connected with the injection joint and the handle through the catheter, the stent catheter comprises a push rod with a guide wire cavity inside, the push rod comprises a stent component, an inner tube, an outer sheath tube and a sealing switch, and the guide wire comprises a preformed structure positioned at the front end of the guide wire. The guide wire is used for improving the guide insertion of the cryoablation system, a stable channel is formed on the inner side of the balloon through the support of the bracket component, vascular embolism caused by balloon dilatation compression is avoided, liquid nitrogen can be continuously input under the condition of not interrupting blood flow, and the liquid nitrogen is repeatedly and circularly extracted and injected, so that the consequences of serious ischemia at the far end and the like caused by target vascular occlusion in operation are avoided.
Description
Technical Field
The invention relates to a medical instrument technology, which is applied to cardiovascular intervention operation, in particular to a blood flow uninterrupted cryoablation system and a cryoablation method.
Technical Field
When atrial fibrillation cryoballoon ablation is clinically carried out, the catheter is generally conveyed to a target pulmonary vein through atrial septum puncture, and the cryoablation instrument conveys liquid N2O to an inner balloon of the balloon catheter through a coaxial connection and an ultrafine lumen (injection tube) of a cryoablation catheter body. After the balloon is inflated and X-rays are positioned to determine the blocking condition of the balloon, ablation is carried out, liquid N2O in the balloon is gasified during ablation, heat of surrounding tissues is absorbed, and target tissues are rapidly frozen to achieve an ablation effect. The cryoablation instrument controls safe transportation and back pumping of N2O, and gaseous N2O is pumped back to the cryoablation instrument through negative pressure vacuum and finally discharged in a tail gas form through a hospital exhaust system.
The cryoballoon widely used in clinic at present is only aimed at pulmonary vein potential isolation of atrial fibrillation, so that the ablated target blood vessel is only aimed at pulmonary vein, and the cryoballoon cannot be widely applied to blood vessel cryoablation (such as renal artery, pulmonary artery and branch artery thereof) in other fields, and main limiting factors include: 1. when in cryoablation, the larger the area of the head end of the catheter (i.e. the balloon) and the tissue is required, the more heat is removed, so that the blood flow of a target blood vessel is interrupted in the ablation of the traditional cryoballoon, and the artificial embolism is extremely easy to be caused when the target blood vessel such as the renal artery, the pulmonary artery and the branch artery is ablated; 2. the main limitation of traditional cryoablation therapy is the narrow indication, and the traditional cryoballoon catheter is specially designed for pulmonary vein anatomy, and is mainly applied to pulmonary vein isolation at present. For paroxysmal atrial fibrillation patients with trigger foci of non-pulmonary vein origin (such as superior vena cava, coronary sinus ostium, etc.), only other ablation catheters can be used for ablation; 3. the prior ablation treatment for removing pulmonary artery sympathsis is only point-to-point radio frequency ablation, and ablation and ending are limited, but the tablet injury of the traditional cryoballoon cannot be applied to the treatment of pulmonary artery hypertension due to various limitations; 4. at present, the renal sympathetic ablation is used for treating hypertension, heart failure and the like by point-to-point radio frequency ablation, often combined with severe complications such as severe pain in operation, and has no effective and monitorable intraoperative end point, but the tablet injury of the traditional cryoballoon cannot be applied to the sympathetic ablation treatment of renal arteries due to various limitations; 5. the traditional balloon is of a spherical structure rather than a tubular shape, and is limited to the mouth of a target blood vessel in the ablation operation, so that the distal ablation of the blood vessel cannot be performed. 6. Since the catheter is not provided with a blood flow guiding hole and a catheter, there is no aspiration or injection function. After the target vessel is fed with the sheath, air bubbles or thrombus possibly existing in the sheath cannot be sucked, anticoagulant preparations (such as heparin saline) and other therapeutic drugs cannot be injected into the sheath, and real-time angiography cannot be realized.
Disclosure of Invention
In order to solve the problems, the invention provides a blood flow uninterrupted cryoablation system and a cryoablation method, and the technical scheme adopted by the invention is as follows:
The system comprises a balloon catheter, a stent catheter and a guide wire, wherein the balloon catheter is connected with the stent catheter through the guide wire;
The balloon catheter comprises a special-shaped balloon, a catheter, an injection joint and a handle which are sequentially connected, wherein a special-shaped guide hole used for being connected with a guide wire is formed in the special-shaped balloon, so that blood diversion can be realized while cryoablation at a focus position is met, relative occlusion of an ablation target blood vessel is prevented, and meanwhile, the balloon catheter is guided to be inserted as a guide hole of the guide wire in a folded state. The front and back of the balloon is respectively provided with a developing ring so as to identify the balloon position in radiography, the inside of the special-shaped balloon is divided into three inner cavities which are respectively connected with an injection joint and a handle through a catheter, the two inner cavities connected with the handle are respectively an injection cavity and an output cavity of liquid nitrogen, the handle can be used for controlling the injection and the output of the liquid nitrogen, the continuous expansion of the balloon body and the continuous cryoablation of the vessel wall are realized by controlling the flow, and the inner cavity connected with the injection joint is a contrast agent injection cavity which can be used for injecting contrast agent;
the support catheter comprises a push rod with a guide wire cavity inside, the push rod comprises a support component, an inner tube, an outer sheath tube and a sealing switch, the support component is positioned at the front end of the push rod and is provided with a developing ring, the sealing switch is arranged at the rear end of the push rod, the inner tube is connected with the support component, the outer side of the inner tube and the outer side of the support component are provided with the outer sheath tube, the other end of the inner tube is provided with a push block and a stop switch, and the support can be extended and contracted forwards and backwards by pushing the inner tube;
the guide wire comprises a preformed structure which is positioned at the front end of the guide wire and is used for conveniently guiding the guide wire into a target blood vessel in the inserting process.
Furthermore, the injection joint at the tail end of the balloon catheter is provided with a switch valve, and the switch valve is used for injecting contrast medium and avoiding blood backflow.
Further, the support assembly comprises a plurality of supports which are fixed in a front-back overlapping mode, the support effect is improved, the inner special-shaped guide holes are prevented from being blocked due to the influence of pressure after the balloon is expanded, so that the blood flow is influenced, meanwhile, when the push-pull rod is pushed, the front-back linkage between the supports can be realized, the developing ring is arranged at the rear end of the inner portion of each support, the developing positioning of the support can be realized, and the limiting when the support is expanded can be realized.
Furthermore, the bracket is made of nickel-titanium alloy material and is shaped through heat treatment so as to realize free expansion in operation.
Further, a screwing device is arranged in the stop switch on the inner tube of the stent catheter and is used for keeping the support or the forward extension state of the stent continuously and effectively.
Furthermore, the inner tube of the stent catheter is provided with a color ring mark, and the color ring mark is used for judging whether the stent component is fully received in the outer sheath tube or not by identifying the position of the color ring in the process of pushing the outer sheath tube.
Furthermore, the pushing rod of the stent catheter is made of a polymer material with certain rigidity and flexibility, so that the stent catheter is smoothly bent in the inserting process and the function of pushing the stent assembly can be realized.
Further, the sealing switch of the support catheter is provided with a silica gel cushion, and the silica gel cushion is used for screwing the sealing switch after being inserted into a focus position, so that the sealing of the tail end of the catheter cavity can be realized by the inner silica gel cushion, and blood backflow is avoided.
Further, a position indication point is arranged on the outer side of the rear end of the inner tube of the stent catheter and used for identifying whether the stent assembly is fully recovered or released.
In another aspect of the present invention, a cryoablation method employing the above-described uninterruptible blood flow cryoablation system is also included, comprising the steps of:
S1, guiding a stent catheter into a balloon catheter through a guide wire, wherein a stent assembly is positioned at the special-shaped balloon;
S2, pushing a pushing rod on the stent catheter, wherein the stent assembly is pushed by an inner tube of the pushing rod and is converted into a supporting state from a forward extending state, so that a special-shaped balloon of the balloon catheter is deformed, a stable channel is formed through a stop switch, and the balloon is prevented from expanding;
s3, continuously and circularly pumping out and injecting liquid nitrogen into the injection cavity and the output cavity of the liquid nitrogen through the handle of the balloon catheter, connecting the handle with the balloon liquid nitrogen injection cavity and the output cavity of the balloon catheter through the catheter, controlling the volume of the balloon body and continuously cryoablation of the vessel wall through controlling the flow of the liquid nitrogen, and injecting the contrast agent into the injection cavity through connecting the contrast agent injection cavity of the balloon cavity through the injection joint.
The invention has the advantages that the guide insertion of the cryoablation system is improved through the guide wire, and the stable channel is formed inside the balloon due to the support of the bracket component through the cryoablation guided by the balloon catheter and the bracket catheter, so that the vascular pipeline is prevented from being completely sealed due to the expansion and the compression of the balloon, and the vascular embolism is caused. Meanwhile, liquid nitrogen can be continuously input under the condition of not interrupting blood flow, so that the blood vessel can be continuously cryoablation, repeated circulation of liquid nitrogen extraction and injection due to temperature rise and cryoablation failure of the liquid nitrogen are avoided, and the consequences of serious ischemia at the far end and the like caused by target blood vessel occlusion in operation are avoided.
Drawings
Fig. 1 is a schematic view of the structure of a balloon catheter of an uninterrupted blood flow cryoablation system of the present invention.
Fig. 2 is a schematic view of the structure of a balloon catheter balloon portion of an uninterrupted blood flow cryoablation system of the present invention.
Fig. 3 is a schematic view of the structure of a stent catheter of a cryoablation system without interrupting blood flow in accordance with the present invention.
Fig. 4 is a schematic illustration of the stent assembly of the stent catheter of the present invention after expansion without interruption of the blood flow cryoablation system.
Fig. 5 is a schematic view of the structure of a stent catheter of the present invention after the stent assembly is received into the outer sheath.
Fig. 6-14 are flow diagrams of a cryoablation method performed by an uninterruptible blood flow cryoablation system of the present invention.
Wherein: 1-special-shaped balloons, 2a and 2 b-balloon developing rings, 3-catheters, 4-injection joints, 5-handles, 6-pushing rods, stents in 7a, 7b and 7 c-stent assemblies, 8a,8b and 8 c-stent developing rings, 9-inner tubes, 10-outer sheath tubes, 11-pushing blocks, 12-stop switches, 13-sealing switches, 14-special-shaped guide holes and 15-guide wires.
Detailed Description
In order to enable those skilled in the art to better understand the present invention, a further description of the technical solution adopted by the present invention is provided below with reference to the accompanying drawings and examples.
Example 1
As shown in fig. 1, an embodiment of a balloon catheter of an uninterrupted blood flow cryoablation system according to the present invention is shown, wherein the balloon catheter comprises a special-shaped balloon 1, two developing rings 2a and 2b are arranged in the special-shaped balloon 1, the developing rings 2a and 2b are used for identifying balloon positions in radiography, therefore, the developing ring 2a is positioned at the front part of the special-shaped balloon, the developing ring 2b is positioned at the rear part of the special-shaped balloon, three inner cavities, namely a liquid nitrogen injection cavity and a liquid nitrogen output cavity, are arranged in the special-shaped balloon, and the three inner cavities are connected with a catheter 3, the catheter 3 is respectively connected with an injection joint 4 and a handle 5, the injection joint 4 is used for injecting contrast agent, the injection joint 4 is connected with the contrast agent injection cavity of the special-shaped balloon 1 through the catheter 3, the handle 5 is used for controlling injection and outflow of liquid nitrogen, and the handle 5 is connected with the liquid nitrogen injection cavity and the liquid nitrogen output cavity of the special-shaped balloon 1 through the catheter 3, so that the liquid nitrogen injection cavity and the liquid nitrogen output cavity can circulate in the special-shaped balloon.
As shown in fig. 2, the balloon is further provided with a special-shaped guide hole, when the balloon is in a folded state, the guide wire can penetrate through the special-shaped guide hole, and when the balloon is in an expanded state, the guide wire can guide blood to pass through the special-shaped guide hole, so that the ablation target blood vessel is prevented from being blocked relatively.
In the above figures, it should be noted that the injection joint is provided with a switch valve for injecting contrast medium and avoiding blood backflow.
Example 2
As shown in fig. 3, in an embodiment of a stent catheter of an uninterrupted blood flow cryoablation system in the present invention, the stent catheter includes a push rod 6, the front end of the push rod 6 is a stent assembly 7, at least one stent is disposed on the stent assembly 7, as shown in the figure, three stents are disposed on the stent assembly, and are respectively a stent 7a, 7b and 7c, wherein the three stents are stacked front and back, the more the number of the set stents is increased, the more obvious the supporting effect is achieved, the blockage of an internal special-shaped guide hole due to the influence of pressure is avoided after the balloon is expanded, thereby influencing the blood flow, and a developing ring 8, such as 8a, 8b and 8c in the figure, is mounted at the rear end of each stent, for realizing the development positioning of the stent and the limit of the stent when the stent is opened. The pushing pipe is further provided with an inner pipe 9 and an outer sheath pipe 10, the inner pipe 9 is connected with the support assembly 7, the outer sheath pipe 10 is located outside the inner pipe 9 and the support assembly 7, the inner pipe 9 is further provided with a pushing block 11 and a stop switch 12, and the pushing block 11 pushes the inner pipe 9 to enable the inner pipe 9 to push the support assembly 7.
As shown in fig. 4 and 5, the support assembly 7 can automatically change from a forward extending state to a supporting state after extending out of the outer sheath 10, so as to support the special-shaped balloon 1, the stop switch 12 is used for enabling the support on the support assembly 7 to keep the forward extending state or the supporting state, and the rear end of the pushing rod 6 is provided with a sealing switch 13, and the sealing switch is used for sealing the tail end of the lumen to avoid blood backflow.
The leading end of the guide wire is of a pre-shaped structure, so that the guide wire can conveniently guide into the left pulmonary artery or the right pulmonary artery in the inserting process.
In the above-mentioned figures, it should be noted that the brackets 7a, 7b, 7c are made of nitinol, and are shaped by heat treatment, so as to realize free expansion in surgery, a screwing device is provided in a stop switch on an inner tube of the bracket catheter, so as to keep the support of the bracket or continuously and effectively in a forward extending state, a color ring mark is provided on the inner tube of the bracket catheter, so that in the process of pushing the sheath tube, whether the bracket component is fully retracted into the sheath tube is judged by identifying the color ring position, a push rod of the bracket catheter adopts a polymer material with certain rigidity and flexibility, so that the bracket catheter insertion process is smoothly bent and the function of pushing the bracket component can be realized, a silica gel cushion is provided in a sealing switch of the bracket catheter, so that after the bracket catheter is inserted into the focus position, the sealing switch is screwed, the sealing of the inner silica gel cushion can realize the end of the catheter cavity, so as to avoid blood backflow, and a position indication point is provided on the outer side of the inner tube of the bracket catheter, so as to identify whether the bracket component is fully retracted or released.
Example 3
A specific description of how the cryoablation method of the present invention can be performed using an uninterrupted blood flow cryoablation system is described below with reference to the accompanying drawings, and with reference to examples 1 and 2.
In this embodiment, the method includes the steps of:
S1, as shown in FIG. 6, inserting a guide wire 15 and delivering the guide wire to a left pulmonary artery;
S2, installing an injector filled with contrast agent on an injection joint 4 at the tail end of the balloon catheter, opening a switch valve, injecting the contrast agent, and closing the switch valve on the injection joint 4 after the air in the inner cavity of the catheter 3 is exhausted outside the body;
S3, as shown in fig. 7, the tail end of the guide wire 15 passes through the special-shaped guide hole 14 on the balloon 1 to guide the balloon catheter to enter the focus position, and contrast agent can be injected in the guiding process to identify the state of the focus position;
s4, as shown in figures 8 and 9, opening a sealing switch 13 at the tail part of the stent catheter, penetrating the tail end of a guide wire 15 from a guide wire hole on the stent catheter, guiding the stent catheter to pass through a balloon special-shaped guide hole to reach a focus, and closing the sealing switch 13;
s5, as shown in FIG. 10, after the stent assembly 7 is judged to have entered the covering position of the balloon 1 through radiography, the stent assembly 7 is pushed out of the outer sheath 10 through the inner tube of the push tube, the push rod 6 is pulled back until the stent assembly 7 reaches a fully supported state, and the stop switch 12 is screwed to fix the push rod 6;
s6, as shown in FIG. 11, continuously injecting liquid nitrogen into the balloon 1 through the handle 5, and expanding the balloon 1 to cryoablate the focus;
S7, as shown in FIG. 12, evacuating liquid nitrogen in the balloon 1 after ablation is completed;
S8, as shown in FIG. 13, opening the stop switch 12, pushing the push-pull rod 6, fully extending the bracket assembly 7, and screwing the stop switch 12 to fix the push-pull rod 6;
S9, pushing the outer sheath 10, identifying whether the stent assembly 7 is fully received in the outer sheath 10 according to the mark point of the inner tube 9, taking out the guide wire 15 and the stent catheter together after receiving, and taking out the balloon catheter.
The special-shaped balloon and the front and rear developing rings are arranged at the front end of the balloon catheter, so that the balloon position can be identified in radiography; the balloon inner cavity is connected with the handle through the catheter to realize internal communication, and the control handle can be used for injecting liquid nitrogen or outputting liquid nitrogen in an operation; the end of the catheter is connected with an injection joint, so that the injection of contrast agent can be realized.
The inside of the multi-section telescopic support catheter is provided with a pushing rod, the front end of the pushing rod is provided with a plurality of supports, the front end of the pushing rod is fixedly connected with the front end of a first support, meanwhile, the pushing rod on the inner side of the support is provided with a plurality of developing rings, and the tail end of the pushing rod is provided with a sealing switch; the inner tube outside the pushing rod is fixedly connected with the rear end of the last bracket, so that the bracket can extend and retract forwards and backwards, and the tail end of the inner tube is provided with a stop switch; the outer sheath tube outside the balloon catheter is provided with a pushing block at the tail end.
The guide wire has a pre-shaped front end, and is conveniently guided into a target blood vessel, such as a left pulmonary artery or a right pulmonary artery, in the inserting process.
By the technical scheme, the guiding insertion of the cryoablation system is improved, the cryoablation under the continuous balloon guiding can be realized under the condition of not interrupting blood flow, and the consequences such as severe ischemia at the far end caused by target vascular occlusion in operation are avoided.
The above examples only show the preferred embodiments of the present invention, and the emphasis is on the cryoablation system and the cryoablation method, and the matched parts are only examples, which are more specific and detailed, and are not intended to limit the invention to the accessories and are not construed as limiting the scope of the invention. It should be noted that modifications, improvements and substitutions can be made by those skilled in the art without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.
Claims (6)
1. An uninterrupted blood flow cryoablation system, comprising a balloon catheter, a stent catheter and a guide wire, wherein the balloon catheter is connected with the stent catheter through the guide wire; the balloon catheter comprises a special-shaped balloon, a catheter, an injection joint and a handle which are sequentially connected, wherein a special-shaped guide hole used for being connected with a guide wire is formed in the special-shaped balloon, a developing ring is respectively arranged in front of and behind the inside of the special-shaped balloon, the inside of the special-shaped balloon is divided into three inner cavities which are respectively connected with the injection joint and the handle through the catheter, two inner cavities connected with the handle are respectively an injection cavity and an output cavity of liquid nitrogen, and the inner cavity connected with the injection joint is a contrast agent injection cavity;
The support catheter comprises a push rod with a guide wire cavity inside, the push rod comprises a support component, an inner tube, an outer sheath tube and a sealing switch, the support component is positioned at the front end of the push rod and is provided with a developing ring, the sealing switch is arranged at the rear end of the push rod, the inner tube is connected with the support component, the outer side of the inner tube and the outer side of the support component are provided with the outer sheath tube, and the other end of the inner tube is provided with a push block and a stop switch;
the guide wire comprises a preformed structure, and the preformed structure is positioned at the front end of the guide wire;
The support assembly comprises a plurality of supports which are overlapped and fixed back and forth, and the developing ring is arranged at the inner rear end of each support;
A screwing device is arranged in a stop switch on the inner tube of the stent catheter and is used for keeping the support of the stent or the continuous and effective forward extension state;
The inner tube of the stent catheter is provided with a color ring mark which is used for judging whether the stent component is fully received in the outer sheath tube or not by identifying the position of the color ring in the process of pushing the outer sheath tube.
2. The cryoablation system of claim 1 wherein the injection connector of the balloon catheter is provided with an on-off valve for injecting contrast agent and preventing blood reflux.
3. The cryoablation system of claim 1 wherein the scaffold is a nickel titanium alloy material and is shaped by a heat treatment.
4. The cryoablation system of claim 1 wherein the pusher bar of the stent catheter is a polymeric material having a degree of rigidity and flexibility.
5. The cryoablation system of claim 1 wherein a silicone cushion is provided in the sealing switch of the stent catheter for sealing the lumen of the catheter to prevent blood reflux.
6. The cryoablation system of claim 1 wherein a location indicator is provided on the outside of the rear end of the inner tube of the stent catheter for identifying whether the stent assembly is fully retrieved or released.
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| CN112971964B (en) * | 2021-03-02 | 2022-04-05 | 首都医科大学附属北京安贞医院 | Balloon for cardiac surgery and ablation device |
| CN113384341A (en) * | 2021-07-06 | 2021-09-14 | 海杰亚（北京）医疗器械有限公司 | Freezing sacculus device for treating natural cavity diseases |
| CN115153814B (en) * | 2022-06-23 | 2023-04-14 | 上海玮琅医疗科技有限公司 | Bracket type radio frequency ablation catheter |
| CN116236237B (en) * | 2022-12-21 | 2024-01-26 | 南京思脉德医疗科技有限公司 | Foramen ovale plugging device and plugging method |
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