CN216091021U - Device for assisting administration in corneal cross-linking operation - Google Patents
Device for assisting administration in corneal cross-linking operation Download PDFInfo
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- CN216091021U CN216091021U CN202121996540.1U CN202121996540U CN216091021U CN 216091021 U CN216091021 U CN 216091021U CN 202121996540 U CN202121996540 U CN 202121996540U CN 216091021 U CN216091021 U CN 216091021U
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Abstract
A device for assisting drug delivery in corneal cross-linking surgery comprises a negative pressure adsorption part which is of a ring-shaped structure integrally, wherein an internal air cavity is arranged on the negative pressure adsorption part, a ventilation interface communicated with the internal air cavity is arranged on the negative pressure adsorption part, an opening is formed in the lower end of the internal air cavity, an eyeball surface contact part suitable for being attached to and contacting with the surface of an eyeball is formed at the opening of the negative pressure adsorption part, and when air is pumped through the ventilation interface to generate negative pressure in the internal air cavity, the negative pressure adsorption part is adsorbed on the eyeball through the eyeball surface contact part to form a liquid storage tank surrounding the surface of the eyeball. The device is used for assisting in the administration in the corneal crosslinking operation, so that the loss of riboflavin can be prevented, and the utilization rate and the absorption degree of the riboflavin solution can be improved.
Description
Technical Field
The utility model relates to a device for assisting drug delivery in corneal crosslinking surgery.
Background
The ultraviolet ray A riboflavin cornea crosslinking therapy is a new method for inducing corneal stroma collagen fibers to crosslink with each other by adopting 370nm ultraviolet ray A light and photosensitizer riboflavin, thereby improving corneal hardness and changing biological performance, and is used for treating keratoconus disease, dilated corneal disease and the like.
The photosensitizer riboflavin (i.e. vitamin B2) is excited to triplet state under the action of ultraviolet light with wavelength of 370nm to generate active oxygen family mainly containing singlet oxygen. The reactive oxygen species can react with various molecules to induce chemical crosslinking reaction (type II photochemical reaction) between amino groups of collagen fibers, thereby increasing the mechanical strength of the collagen fibers and the capability of resisting corneal dilation, and 370nm is the absorption peak wavelength of riboflavin. Therefore, the absorption of riboflavin greatly affects the crosslinking result, and although many techniques such as continuous ultrasonic induction and ion introduction are proved to be effective for inducing the riboflavin to be immersed into the corneal stroma, the riboflavin is only intermittently dripped on the cornea during the actual operation and is easily lost, and the absorption efficiency is low, so that the final crosslinking effect is not ideal.
The tight connection of corneal epithelial cells leads to the fact that riboflavin solution is difficult to permeate into corneal stromal cells, the absorption degree of the riboflavin solution determines the final effect of crosslinking to a great extent, and in view of different operations from research, the adopted mode is often very simple to drip and permeate the riboflavin solution, most of riboflavin is directly lost and wasted, the riboflavin can be absorbed into stroma a little, and the final operation effect is difficult to control.
It is to be noted that the information disclosed in the above background section is only for understanding the background of the present application and thus may include information that does not constitute prior art known to a person of ordinary skill in the art.
SUMMERY OF THE UTILITY MODEL
The main purpose of the present invention is to overcome the above mentioned drawbacks of the background art, and to provide a device for assisting drug delivery in corneal cross-linking surgery, so as to prevent the loss of riboflavin and improve the utilization rate and absorption degree of riboflavin solution.
In order to achieve the purpose, the utility model adopts the following technical scheme:
a device for assisting drug delivery in corneal cross-linking surgery comprises a negative pressure adsorption part which is of a ring-shaped structure integrally, wherein an internal air cavity is arranged on the negative pressure adsorption part, a ventilation interface communicated with the internal air cavity is arranged on the negative pressure adsorption part, an opening is formed in the lower end of the internal air cavity, an eyeball surface contact part suitable for being attached to and contacting with the surface of an eyeball is formed at the opening of the negative pressure adsorption part, and when air is pumped through the ventilation interface to generate negative pressure in the internal air cavity, the negative pressure adsorption part is adsorbed on the eyeball through the eyeball surface contact part to form a liquid storage tank surrounding the surface of the eyeball.
Further:
the ring-shaped structure is a circular ring.
The eyeball surface contact part is in line contact with the eyeball surface, surface contact with the eyeball surface or a combination of the line contact and the surface contact with the eyeball surface.
The negative pressure adsorption part comprises a top wall, an inner side wall and an outer side wall, wherein the inner side wall and the outer side wall are connected with the top wall, and the eyeball surface contact part is formed at the bottom ends of the inner side wall and the outer side wall.
The eyeball surface contact portion includes first and second arc portions formed at bottom ends of the inner and outer side walls, respectively, the first and second arc portions being curved toward the inside air cavity.
The negative pressure adsorption part is of an elastic deformation structure, and elastic deformation is generated when the difference between the internal air pressure and the external air pressure of the internal air cavity reaches a threshold value, so that at least one part of the eyeball surface contact part is separated from the eyeball, and the internal air cavity is elastically restored after being communicated with the external atmosphere.
The negative pressure suction forms an enclosure for the pupil, the cornea, or a larger surface area of the eye.
The eyeball surface contact part is made of medical grade plastics.
The negative pressure adsorption part is made of medical grade plastics through integral molding.
The inner wall of the liquid storage tank is provided with at least one scale mark for indicating the amount of the liquid.
The utility model has the following beneficial effects:
the utility model provides a device for assisting drug administration in a corneal crosslinking operation, which can be adsorbed on an eyeball of a human body through negative pressure and surround an area (such as a cornea) on the surface of the eyeball to be administered to form a liquid storage tank, a riboflavin solution can be added into the liquid storage tank, the loss of riboflavin is prevented, the utilization rate and the absorption degree of the riboflavin solution are improved, the crosslinking effect is improved, the use of a medicament in the corneal crosslinking operation can be saved, and the medicament cost of the corneal crosslinking operation is reduced.
Drawings
Figure 1 is an isometric view of one embodiment of a device of the present invention for use in assisting the administration of a drug during a corneal cross-linking procedure.
Fig. 2 is a front view of the device shown in fig. 1.
Fig. 3 is a cross-sectional view taken along line A-A of the device shown in fig. 2 attached to an eyeball.
Fig. 4 is a cross-sectional view of the device shown in fig. 2 at the instant of deformation when the negative pressure is overloaded.
Fig. 5 is a schematic view of the device of fig. 1 when connected to a syringe.
Detailed Description
The embodiments of the present invention will be described in detail below. It should be emphasized that the following description is merely exemplary in nature and is not intended to limit the scope of the utility model or its application.
It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or be indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or be indirectly connected to the other element. In addition, the connection may be for either a fixed or coupled or communicating function.
It is to be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in an orientation or positional relationship indicated in the drawings for convenience in describing the embodiments of the present invention and to simplify the description, and are not intended to indicate or imply that the referenced device or element must have a particular orientation, be constructed in a particular orientation, and be in any way limiting of the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the embodiments of the present invention, "a plurality" means two or more unless specifically limited otherwise.
Referring to fig. 1 to 5, an embodiment of the present invention provides a device for assisting drug delivery in a corneal cross-linking operation, including a negative pressure adsorption part having a ring-shaped structure, the negative pressure adsorption part being provided with an internal air cavity 300, the negative pressure adsorption part being provided with a ventilation interface 100, the ventilation interface 100 being communicated with the internal air cavity 300 through a channel 110, the internal air cavity 300 having an opening at a lower end thereof, the negative pressure adsorption part being formed with an eyeball surface contact part adapted to be in contact with an eyeball surface at the opening, and when a negative pressure is generated in the internal air cavity 300 by evacuating through the ventilation interface 100, the negative pressure adsorption part being adsorbed on the eyeball through the eyeball surface contact part to form a reservoir 200 surrounding the eyeball surface by one area. In operation, a device (such as a syringe) with an air pumping function can be connected with the ventilation interface 100 for air pumping to make the air pressure of the internal air cavity 300 of the negative pressure adsorption part lower than the atmospheric pressure, so as to generate negative pressure, the negative pressure adsorption part is arranged on the eyeball 900 of a human body by means of the negative pressure and surrounds an area (such as a cornea) on the surface of the eyeball to be dosed to form a liquid storage tank 200, a riboflavin solution can be added into the liquid storage tank 200, the loss of the riboflavin is prevented, the utilization rate and the absorption degree of the riboflavin solution are improved, so that the cross-linking effect can be improved, the use of a medicament in a corneal cross-linking operation can be saved, and the medicament cost of the corneal cross-linking operation can be reduced.
In various embodiments, the negative pressure suction may form an enclosure for the pupil, the cornea, or a larger surface area of the eye.
In various embodiments, the contact between the eyeball surface contact portion and the eyeball surface may be line contact, surface contact, or a combination of line contact and surface contact.
Referring to fig. 1 to 5, in a preferred embodiment, the negative pressure adsorption part of the ring-shaped structure is a circular negative pressure adsorption part. It is understood that the ring-shaped structure is not limited to a circular ring shape, and it is only necessary that the negative pressure suction part can form a surrounding of a certain area of the surface of the eyeball where corneal cross-linking operation is required.
Referring to fig. 1 to 5, in a preferred embodiment, the negative pressure suction part includes a top wall, and an inner sidewall and an outer sidewall connected to the top wall, and the eyeball surface contact part is formed at bottom ends of the inner sidewall and the outer sidewall and can be attached to an eyeball of a human body.
Referring to fig. 3 to 4, in a preferred embodiment, the eyeball surface-contacting portion includes first and second arc-shaped portions formed at the bottom ends of the inner and outer side walls, respectively, and the first and second arc-shaped portions are bent inward toward the inner air chamber 300. The arc part can change the curvature under the condition of negative pressure to adapt to eyeballs with different curvature radiuses.
In a preferred embodiment, the negative pressure absorbing part is an elastic deformation structure, and is elastically deformed when the difference between the internal air pressure and the external air pressure of the internal air cavity 300 reaches a threshold value, so that at least a part of the eyeball surface contact part is separated from the eyeball, and the internal air cavity 300 is elastically restored after being communicated with the external atmosphere. Fig. 4 is a cross-sectional view of an embodiment of the device at the instant of deformation during negative pressure overload, after which the inner negative pressure region is vented to the outside atmosphere, and the shape of the device is subsequently elastically restored. This deformation is only one example and does not represent that all deformations are so.
In a preferred embodiment, the material of the eyeball surface contact part is medical grade plastic. In a more preferred embodiment, the negative pressure adsorption part is integrally molded from medical grade plastic. It is understood that the ocular surface contact portion or the negative pressure attachment portion may be made of medical grade sterile materials, including but not limited to medical grade plastics.
In a preferred embodiment, the inner wall of the reservoir 200 is provided with at least one scale mark for indicating the amount of liquid.
Specific embodiments of the present invention are further described below.
A device for assisting in the administration of a drug during a corneal crosslinking procedure, which device can be easily conformed to the surface of a human eyeball, and the contact surface of the device can be adapted to a spherical surface, wherein the contact mode comprises but is not limited to line contact, surface contact, and the combination of line contact and surface contact. In this embodiment, the bonding contact manner of the device is line contact.
The periphery of the device is provided with a ventilation interface 100, a channel 110 leading to an internal negative pressure area is arranged in the ventilation interface 100, the ventilation interface 100 can be connected with a negative pressure source through a pipeline, so that a negative pressure environment is formed on the device and is adsorbed on the eyeball of the human body, the adsorption force of the negative pressure environment on the eyeball of the human body is controllable, and the degree of the adsorption force can be shown on the device. In one embodiment, the vent interface 100 on the periphery of the device is piped to a syringe, which can be made to create negative pressure, and the scale on the syringe can indicate the degree of suction. The adsorption force has an overload failure function, when the internal air pressure is too low, the material of the device is difficult to support the strength of negative pressure difference and elastically deforms, the inside and the outside of the device are communicated after deformation, the pressure is recovered, and the device elastically recovers.
The device is attached to an area of the human eyeball surrounding the eyeball, the center of the surrounding area generally aligned with the center of the corneal crosslinking area, forming a reservoir 200 into which riboflavin may be added. The size of the surrounding area can be set according to needs, and the requirement of surrounding pupil, cornea or larger area can be met.
The device is provided with at least one liquid level scale mark which can prompt the amount of the added liquid. In one embodiment, the interior wall of the reservoir 200 has three graduations 201, 202, 203, which are yellow, green, and red, respectively. Yellow indicates low fluid, green indicates moderate fluid, and red indicates high fluid.
The device can be conveniently taken down from the eyeball. In one embodiment, the device is removed by introducing gas into the device to restore or exceed the internal gas pressure. In another embodiment, the device is removed by deforming the device by an external force resulting in communication of internal and external air pressures.
The material of the device is medical grade sterile material, including but not limited to medical grade plastic. The device may be disposable.
The background of the present invention may contain background information related to the problem or environment of the present invention and does not necessarily describe the prior art. Accordingly, the inclusion in the background section is not an admission of prior art by the applicant.
The foregoing is a more detailed description of the utility model in connection with specific/preferred embodiments and is not intended to limit the practice of the utility model to those descriptions. It will be apparent to those skilled in the art that various substitutions and modifications can be made to the described embodiments without departing from the spirit of the utility model, and these substitutions and modifications should be considered to fall within the scope of the utility model. In the description herein, references to the description of the term "one embodiment," "some embodiments," "preferred embodiments," "an example," "a specific example," or "some examples" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Various embodiments or examples and features of various embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction. Although embodiments of the present invention and their advantages have been described in detail, it should be understood that various changes, substitutions and alterations can be made herein without departing from the scope of the claims.
Claims (10)
1. A device for assisting drug delivery in corneal cross-linking surgery is characterized by comprising a negative pressure adsorption part which is integrally of a ring-shaped structure, wherein an internal air cavity is arranged on the negative pressure adsorption part, a ventilation interface communicated with the internal air cavity is arranged on the negative pressure adsorption part, an opening is formed in the lower end of the internal air cavity, an eyeball surface contact part suitable for being attached to and contacting with the surface of an eyeball is formed at the opening of the negative pressure adsorption part, and when air is pumped out through the ventilation interface to generate negative pressure in the internal air cavity, the negative pressure adsorption part is adsorbed on the eyeball through the eyeball surface contact part to form a liquid storage tank surrounding one area of the surface of the eyeball.
2. The device of claim 1, wherein the loop-like structure is a circular ring.
3. The apparatus according to claim 1, wherein the eyeball surface contact portion is in contact with the eyeball surface in a manner of line contact, surface contact, or a combination of line contact and surface contact.
4. The apparatus according to claim 1, wherein the negative pressure suction part includes a top wall, and inner and outer side walls connected to the top wall, and the eyeball surface-contacting portion is formed at bottom ends of the inner and outer side walls.
5. The apparatus of claim 4, wherein the eye surface contact portion comprises first and second arcuate portions formed at bottom ends of the inner and outer side walls, respectively, the first and second arcuate portions curving toward the interior lumen.
6. The apparatus according to claim 1, wherein the negative pressure suction portion is an elastic deformation structure, and is elastically deformed when the difference between the internal and external pressures of the internal air chamber reaches a threshold value, so that at least a portion of the eyeball surface contact portion is separated from the eyeball, resulting in elastic recovery of the internal air chamber after communicating with the external atmosphere.
7. The device of any of claims 1 to 6, wherein the negative pressure suction forms an enclosure for the pupil, the cornea, or a larger surface area of the eye.
8. The device according to any one of claims 1 to 6, wherein the material of the eyeball surface contact portion is medical grade plastic.
9. The device of claim 8, wherein the negative pressure suction portion is integrally formed from a medical grade plastic.
10. A device according to any one of claims 1 to 6, wherein the interior wall of the reservoir is provided with at least one scale marking indicating the amount of liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121996540.1U CN216091021U (en) | 2021-08-24 | 2021-08-24 | Device for assisting administration in corneal cross-linking operation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121996540.1U CN216091021U (en) | 2021-08-24 | 2021-08-24 | Device for assisting administration in corneal cross-linking operation |
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| Publication Number | Publication Date |
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| CN216091021U true CN216091021U (en) | 2022-03-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202121996540.1U Active CN216091021U (en) | 2021-08-24 | 2021-08-24 | Device for assisting administration in corneal cross-linking operation |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117281684A (en) * | 2023-11-24 | 2023-12-26 | 超目科技(北京)有限公司 | Eyeball adsorption device and eyeball adsorption system |
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2021
- 2021-08-24 CN CN202121996540.1U patent/CN216091021U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117281684A (en) * | 2023-11-24 | 2023-12-26 | 超目科技(北京)有限公司 | Eyeball adsorption device and eyeball adsorption system |
| CN117281684B (en) * | 2023-11-24 | 2024-03-29 | 超目科技(北京)有限公司 | Eyeball adsorption device and eyeball adsorption system |
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