CN206515567U - One kind carries property of medicine contact lens - Google Patents
One kind carries property of medicine contact lens Download PDFInfo
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- CN206515567U CN206515567U CN201720209458.7U CN201720209458U CN206515567U CN 206515567 U CN206515567 U CN 206515567U CN 201720209458 U CN201720209458 U CN 201720209458U CN 206515567 U CN206515567 U CN 206515567U
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- membrane sheet
- contact lens
- outer membrane
- drug
- film
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- 239000003814 drug Substances 0.000 title claims abstract description 27
- 239000012528 membrane Substances 0.000 claims abstract description 50
- 210000005252 bulbus oculi Anatomy 0.000 claims abstract description 6
- 239000000017 hydrogel Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 229940079593 drug Drugs 0.000 abstract description 20
- 238000012377 drug delivery Methods 0.000 abstract description 3
- 239000000243 solution Substances 0.000 description 7
- 230000000694 effects Effects 0.000 description 3
- 239000003889 eye drop Substances 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 229940012356 eye drops Drugs 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 238000013268 sustained release Methods 0.000 description 2
- 239000012730 sustained-release form Substances 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000004087 cornea Anatomy 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 229960001193 diclofenac sodium Drugs 0.000 description 1
- 210000001508 eye Anatomy 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- JGMJQSFLQWGYMQ-UHFFFAOYSA-M sodium;2,6-dichloro-n-phenylaniline;acetate Chemical compound [Na+].CC([O-])=O.ClC1=CC=CC(Cl)=C1NC1=CC=CC=C1 JGMJQSFLQWGYMQ-UHFFFAOYSA-M 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
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- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
本实用新型公开一种载药性角膜接触镜，包括外膜片和内膜片。所述外膜片和内膜片均为角膜接触镜(隐形眼镜)。所述外膜片的四周紧贴内膜片的四周，从而形成结合部。使用时，所述内膜片背向外膜片的一面，是与眼球接触的面。所述外膜片的基弧小于内膜片的基弧，从而形成外膜片和内膜片之间的内腔。所述内腔中填充药物。所述内膜片上具有若干通孔。在患者使用时，可以挤出内腔中的空气，将载药性角膜接触镜整体浸入药液中，使得内腔中吸入药液。患者佩戴载药性角膜接触镜时，内腔中药液会通过内膜片上的若干通孔缓慢释放，达到安全、持续、稳定给药之目的。
The utility model discloses a drug-loaded corneal contact lens, which comprises an outer membrane sheet and an inner membrane sheet. Both the outer film and the inner film are contact lenses (contact lenses). The periphery of the outer membrane sheet is in close contact with the periphery of the inner membrane sheet, thereby forming a joint. During use, the side of the inner membrane sheet facing away from the outer membrane sheet is the surface in contact with the eyeball. The base arc of the outer membrane sheet is smaller than the base arc of the inner membrane sheet, thereby forming a lumen between the outer membrane sheet and the inner membrane sheet. Drugs are filled in the cavity. There are several through holes on the inner membrane sheet. When the patient uses it, the air in the inner cavity can be squeezed out, and the drug-loaded corneal contact lens can be completely immersed in the medicinal solution, so that the inner cavity can absorb the medicinal solution. When the patient wears the drug-loaded contact lens, the drug solution in the inner cavity will be released slowly through a number of through holes on the inner film, so as to achieve the purpose of safe, continuous and stable drug delivery.
Description
技术领域technical field
本实用新型涉及医疗器械领域，特别是一种用于眼科治疗的装置。The utility model relates to the field of medical equipment, in particular to a device for ophthalmology treatment.
背景技术Background technique
目前，眼部疾病的治疗是个缓慢的过程，给药途径是全身给药和局部给药。At present, the treatment of eye diseases is a slow process, and the route of administration is systemic administration and local administration.
局部给药包括：滴眼、玻璃体腔内注射、植入缓释装置等，均有不足之处。Topical administration includes: eye drops, intravitreal injection, implantation of sustained-release devices, etc., all of which have deficiencies.
眼用滴剂――需要患者反复点眼，患者的顺应性不稳定，不能遵循指定的治疗方案。顺应性问题包括：没有滴入、无效技术(滴入量小于需要量，过量使用)、滴入次数太多(患者会忘记)。Eye Drops - Requires repeated instillation by the patient, and the patient's compliance is unstable and cannot follow the prescribed treatment plan. Compliance problems include: no instillation, ineffective technique (instill less than needed, overdose), too many instillations (patient forgets).
玻璃体腔内注射以及植入缓释装置――给药容易导致感染、出血等。具有给药不便及引发严重副作用的风险。Intravitreal injection and implantation of sustained-release devices—administration can easily lead to infection, bleeding, etc. It has the risk of inconvenient administration and serious side effects.
发明内容Contents of the invention
本实用新型的目的是解决角膜局部给药的问题。The purpose of the utility model is to solve the problem of local administration of cornea.
为实现本实用新型目的而采用的技术方案是这样的，一种载药性角膜接触镜，包括外膜片和内膜片。The technical solution adopted to realize the object of the utility model is as follows, a drug-loaded contact lens includes an outer film and an inner film.
所述外膜片和内膜片均为角膜接触镜(隐形眼镜)。所述外膜片的四周紧贴内膜片的四周，从而形成结合部。使用时，所述内膜片背向外膜片的一面，是与眼球接触的面。Both the outer film and the inner film are contact lenses (contact lenses). The periphery of the outer membrane sheet is in close contact with the periphery of the inner membrane sheet, thereby forming a joint. When in use, the side of the inner membrane facing away from the outer membrane is the surface in contact with the eyeball.
所述外膜片的基弧小于内膜片的基弧，从而形成外膜片和内膜片之间的内腔。所述内腔中填充药物。The base arc of the outer membrane sheet is smaller than the base arc of the inner membrane sheet, thereby forming a lumen between the outer membrane sheet and the inner membrane sheet. Drugs are filled in the cavity.
所述内膜片上具有若干通孔。There are several through holes on the inner membrane sheet.
一种实施方式中，所述内膜片和外膜片为软性角膜接触镜。In one embodiment, the inner and outer membrane sheets are soft contact lenses.
另一种实施方式中，所述内膜片为硬性角膜接触镜，外膜片为软性角膜接触镜。In another embodiment, the inner film is a rigid contact lens, and the outer film is a soft contact lens.
进一步，所述内膜片的材料为硅水凝胶。Further, the material of the inner membrane sheet is silicon hydrogel.
进一步，所述结合部开有若干微孔。Further, the joint part has several micropores.
进一步，所述通孔的直径小于或等于0.1mm。Further, the diameter of the through hole is less than or equal to 0.1mm.
本实用新型的技术效果是毋庸置疑的：The technical effect of the present utility model is beyond doubt:
1)使用(载药)方便。即，在患者使用时，可以挤出内腔中的空气，将载药性角膜接触镜整体浸入药液中，使得内腔中吸入药液。1) It is convenient to use (drug loading). That is, when the patient uses it, the air in the inner cavity can be squeezed out, and the whole drug-loaded contact lens can be immersed in the medicinal solution, so that the inner cavity can absorb the medicinal solution.
2)避免滴眼治疗时，患者顺应性的问题。2) To avoid the problem of patient compliance during eye drop treatment.
3)避免传统注射或植入材料带来的副作用。即，患者佩戴载药性角膜接触镜时，内腔中药液会通过内膜片上的若干通孔缓慢释放，达到安全、持续、稳定给药之目的。3) Avoid side effects caused by traditional injection or implant materials. That is, when the patient wears the drug-loaded contact lens, the drug solution in the inner cavity will be released slowly through a number of through holes on the inner film, so as to achieve the purpose of safe, continuous and stable drug delivery.
附图说明Description of drawings
图1为本实用新型的结构示意图；Fig. 1 is the structural representation of the utility model;
图2为图1的A-A剖视图。Fig. 2 is a sectional view along line A-A of Fig. 1 .
图中：外膜片1、内膜片2、结合部3、通孔4、内腔5。In the figure: an outer membrane 1, an inner membrane 2, a junction 3, a through hole 4, and an inner cavity 5.
具体实施方式detailed description
下面结合附图和实施例对本实用新型作进一步说明，但不应该理解为本实用新型上述主题范围仅限于下述实施例。在不脱离本实用新型上述技术思想的情况下，根据本领域普通技术知识和惯用手段，做出各种替换和变更，均应包括在本实用新型的保护范围内。The utility model will be further described below in conjunction with the accompanying drawings and embodiments, but it should not be understood that the scope of the above subject matter of the utility model is limited to the following embodiments. Without departing from the above-mentioned technical ideas of the present utility model, various replacements and changes made according to common technical knowledge and conventional means in this field shall be included in the protection scope of the present utility model.
实施例1：Example 1:
参见图1和2，一种载药性角膜接触镜，包括外膜片1和内膜片2。Referring to FIGS. 1 and 2 , a drug-loaded contact lens includes an outer film 1 and an inner film 2 .
所述外膜片1和内膜片2均为角膜接触镜。所述外膜片1的四周紧贴内膜片2的四周，从而形成结合部3。使用时，所述内膜片2背向外膜片1的一面，是与眼球接触的面。Both the outer film 1 and the inner film 2 are contact lenses. The periphery of the outer membrane sheet 1 is in close contact with the periphery of the inner membrane sheet 2 to form a joint 3 . During use, the side of the inner membrane sheet 2 facing away from the outer membrane sheet 1 is the surface in contact with the eyeball.
所述外膜片1的基弧小于内膜片2的基弧，从而形成外膜片1和内膜片2之间的内腔5。所述内腔5中填充药物。The base curve of the outer membrane 1 is smaller than the base curve of the inner membrane 2 , thereby forming a lumen 5 between the outer membrane 1 and the inner membrane 2 . Drugs are filled in the inner cavity 5 .
实施例中，所述内膜片2和外膜片1为软性角膜接触镜，材料为硅水凝胶。内膜片2的基弧根据患者眼球的基弧决定(国人的眼弧大部分在8.4-8.6之间)。用于患者的视力本来就比较差，因此可以不考虑载药性角膜接触镜的光学性能，为了更多的载药，所述外膜片1与内膜片2的差值在2mm左右。In the embodiment, the inner membrane sheet 2 and the outer membrane sheet 1 are soft contact lenses made of silicone hydrogel. The base arc of the intima sheet 2 is determined according to the base arc of the patient's eyeball (most of the eye arcs of Chinese people are between 8.4-8.6). The eyesight of the patient is relatively poor, so the optical performance of the drug-loaded contact lens can be ignored. In order to load more drugs, the difference between the outer film 1 and the inner film 2 is about 2 mm.
所述内膜片2上具有若干通孔4。在患者使用时，可以挤出内腔中的空气，将载药性角膜接触镜整体浸入药液(双氯芬酸钠等)中，使得内腔中吸入药液。患者佩戴载药性角膜接触镜时，内腔中药液会通过内膜片上的若干通孔缓慢释放，达到安全、持续、稳定给药之目的。There are several through holes 4 on the inner membrane sheet 2 . When the patient uses it, the air in the inner cavity can be squeezed out, and the drug-loaded contact lens can be completely immersed in the medicinal solution (diclofenac sodium, etc.), so that the inner cavity can inhale the medicinal solution. When the patient wears the drug-loaded contact lens, the drug solution in the inner cavity will be released slowly through a number of through holes on the inner film, so as to achieve the purpose of safe, continuous and stable drug delivery.
实施例2：Example 2:
一种载药性角膜接触镜，包括外膜片1和内膜片2。A drug-loaded corneal contact lens comprises an outer film 1 and an inner film 2.
所述外膜片1和内膜片2均为角膜接触镜。所述外膜片1的四周紧贴内膜片2的四周，从而形成结合部3。使用时，所述内膜片2背向外膜片1的一面，是与眼球接触的面。Both the outer film 1 and the inner film 2 are contact lenses. The periphery of the outer membrane sheet 1 is in close contact with the periphery of the inner membrane sheet 2 to form a joint 3 . During use, the side of the inner membrane sheet 2 facing away from the outer membrane sheet 1 is the surface in contact with the eyeball.
所述外膜片1的基弧小于内膜片2的基弧，所述内膜片2为硬性角膜接触镜，外膜片1为软性角膜接触镜。The base arc of the outer film 1 is smaller than the base arc of the inner film 2, the inner film 2 is a rigid contact lens, and the outer film 1 is a soft contact lens.
从而形成外膜片1和内膜片2之间的内腔5。所述内腔5中填充药物。所述内膜片2上具有若干通孔4。Thus, an inner cavity 5 between the outer membrane sheet 1 and the inner membrane sheet 2 is formed. Drugs are filled in the inner cavity 5 . There are several through holes 4 on the inner membrane sheet 2 .
优选地，为了改善透气性能，所述结合部3开有若干微孔。Preferably, in order to improve air permeability, the bonding part 3 is provided with several micropores.
Claims (5)
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720209458.7U CN206515567U (en) | 2017-03-06 | 2017-03-06 | One kind carries property of medicine contact lens |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201720209458.7U CN206515567U (en) | 2017-03-06 | 2017-03-06 | One kind carries property of medicine contact lens |
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| CN206515567U true CN206515567U (en) | 2017-09-22 |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107811751A (en) * | 2017-12-08 | 2018-03-20 | 华中科技大学 | A kind of contact lenses for being used to treat xerophthalmia |
| CN107951618A (en) * | 2017-12-08 | 2018-04-24 | 华中科技大学 | A kind of contact lenses for drug treatment fungal keratitis |
| CN108056755A (en) * | 2017-12-08 | 2018-05-22 | 华中科技大学 | A kind of conformal microfluidic device preparation method of curved surface |
| CN108095886A (en) * | 2017-12-08 | 2018-06-01 | 华中科技大学 | A kind of contact lenses for being used to treat glaucoma |
| CN108309555A (en) * | 2018-04-16 | 2018-07-24 | 石凡军 | A kind of anti-glaucoma surgery scarring inhibits and avascular filtering bleb maintenance tool |
| CN108969185A (en) * | 2018-07-06 | 2018-12-11 | 佛山市瑞生海特生物科技有限公司 | Bandage is sterilized by the eyeball that eyelid squeezes sustained release dosage |
| CN109847109A (en) * | 2018-09-11 | 2019-06-07 | 滕宇池 | A kind of contact lens carrying medicine |
-
2017
- 2017-03-06 CN CN201720209458.7U patent/CN206515567U/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107811751A (en) * | 2017-12-08 | 2018-03-20 | 华中科技大学 | A kind of contact lenses for being used to treat xerophthalmia |
| CN107951618A (en) * | 2017-12-08 | 2018-04-24 | 华中科技大学 | A kind of contact lenses for drug treatment fungal keratitis |
| CN108056755A (en) * | 2017-12-08 | 2018-05-22 | 华中科技大学 | A kind of conformal microfluidic device preparation method of curved surface |
| CN108095886A (en) * | 2017-12-08 | 2018-06-01 | 华中科技大学 | A kind of contact lenses for being used to treat glaucoma |
| CN107951618B (en) * | 2017-12-08 | 2019-10-08 | 华中科技大学 | A kind of contact lenses for drug treatment fungal keratitis |
| CN108095886B (en) * | 2017-12-08 | 2019-10-25 | 华中科技大学 | A kind of contact lens for treating glaucoma |
| CN108309555A (en) * | 2018-04-16 | 2018-07-24 | 石凡军 | A kind of anti-glaucoma surgery scarring inhibits and avascular filtering bleb maintenance tool |
| CN108969185A (en) * | 2018-07-06 | 2018-12-11 | 佛山市瑞生海特生物科技有限公司 | Bandage is sterilized by the eyeball that eyelid squeezes sustained release dosage |
| CN108969185B (en) * | 2018-07-06 | 2020-09-29 | 青岛市市立医院 | Eyeball antiseptic bandage that squeezes the sustained release agent through the eyelid |
| CN109847109A (en) * | 2018-09-11 | 2019-06-07 | 滕宇池 | A kind of contact lens carrying medicine |
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