CN215914703U - Device for tumor tissue transplantation - Google Patents

Device for tumor tissue transplantation Download PDF

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Publication number
CN215914703U
CN215914703U CN202121347771.XU CN202121347771U CN215914703U CN 215914703 U CN215914703 U CN 215914703U CN 202121347771 U CN202121347771 U CN 202121347771U CN 215914703 U CN215914703 U CN 215914703U
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needle
fixed
tumor tissue
clearance groove
tube
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CN202121347771.XU
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Chinese (zh)
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王玉光
郑晨
陈可明
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Abstract

The utility model relates to the technical field of medical instruments and discloses a device for tumor tissue transplantation, which comprises a needle tube, wherein the bottom of the needle tube is in threaded connection with a lower threaded cover, a first clearance groove is formed in the middle of the upper surface of the lower threaded cover, a first through hole is formed in the middle of the inner wall of the first clearance groove, a waist penetrating needle is fixed in the middle of the lower surface of the lower threaded cover, an upper threaded cover is in threaded connection with the top of the needle tube, and a second clearance groove is formed in the middle of the upper surface of the upper threaded cover. This device for tumor tissue transplantation is provided with guider in that the guide rail is inside, make not unidimensional straw when injecting the needle tubing inside, through the universal ball of straw extrusion, make the movable rod can remove to a fixed cylinder, the movable rod compresses the spring through driving the slider simultaneously, can make universal ball contact with the straw all the time under the effect of spring, avoided injection needle and needle tubing contact to cause the contaminated phenomenon of tumor tissue, improved work efficiency.

Description

Device for tumor tissue transplantation
Technical Field
The utility model relates to the technical field of medical instruments, in particular to a device for tumor tissue transplantation.
Background
The existing tissue block transplanting method comprises the steps of washing tumor tissues for multiple times by using balanced salt solution, removing blood on the surface of the tumor tissues, soaking the tumor tissues in serum-free culture medium loaded by a sterile culture dish, shearing a target donor into tissue small blocks with the size of 1 cubic millimeter by using small surgical scissors or sucking the tumor small tissues by a lumbar puncture needle, taking a nude mouse or SCID mouse for 6-8 weeks, transferring the extracted tissue blocks into corresponding positions, and then carrying out proper treatment, so that the tumor can continue to grow, and the tumor tissue bulge growth at the inoculated part can be observed in about 1 week by observing every day;
the existing transplantation method comprises the following steps: subcutaneous transplantation, kidney capsule undertransplantation and in situ inoculation, each of which requires the adsorption of tissue mass, but the current method is performed with a lumbar puncture needle during the extraction and transplantation processes.
Some medical device devices currently on the market:
(1) in the tissue transplantation process, most of the existing medical apparatus and instruments are disposable, so that resource waste is caused, and meanwhile, the existing medical apparatus and instruments cannot be adjusted according to the size of the suction pipe, so that the tumor tissue is easily polluted and damaged, and the transplantation failure is caused.
Therefore, we have proposed a device for tumor tissue transplantation so as to solve the problems set forth above.
SUMMERY OF THE UTILITY MODEL
Technical problem to be solved
In view of the above-mentioned shortcomings in the prior art, an object of the present invention is to provide a device for tumor tissue transplantation, so as to solve the problems of the prior art that the devices for tumor tissue transplantation are disposable, which results in waste of resources, and the devices cannot be adjusted according to the size of the suction tube, which easily causes the phenomena of tumor tissue contamination and damage, which results in transplantation failure.
(II) technical scheme
In order to achieve the purpose, the utility model is realized by the following technical scheme:
a device for tumor tissue transplantation comprises a needle tube, wherein the bottom of the needle tube is in threaded connection with a lower threaded cover, a first clearance groove is formed in the middle of the upper surface of the lower threaded cover, a first through hole is formed in the middle of the inner wall of the first clearance groove, a lumbar puncture needle is fixed in the middle of the lower surface of the lower threaded cover, an upper threaded cover is in threaded connection with the top of the needle tube, a second clearance groove is formed in the middle of the upper surface of the upper threaded cover, a second through hole is formed in the middle of the inner bottom wall of the second clearance groove, four guide rails are fixed on the inner wall of the needle tube, sliding strips are connected inside the guide rails in a sliding manner, a limiting strip is fixed on one side of each sliding strip, which is far away from the sliding strip, a connecting column is fixed on one side of the connecting column, which is far away from the limiting strip, a fixed tube is fixed inside the fixed tube in a sliding manner, and is connected with a sliding block, the injection syringe is characterized in that a movable rod is fixed on one side of the sliding block, a spring is fixed on the other side of the sliding block, a universal ball is fixed at one end, away from the sliding block, of the movable rod, a suction tube is arranged inside the needle tube, a compression ball is fixed at the top of the suction tube, and an injection needle is fixed at the bottom of the suction tube.
Preferably, an inner thread groove is formed in the middle of the lower surface of the needle tube, an outer thread ring matched with the inner thread groove is formed in the outer side of the upper end of the lower thread cover, an inner thread matched with the upper thread cover is formed in the inner wall of the upper end of the needle tube, and the top and the bottom of the guide rail are in contact with the lower surface of the upper thread cover and the upper surface of the lower thread cover respectively.
Preferably, the lumbar puncture needle is communicated with the first through hole, and the second through hole is opposite to the first through hole.
Preferably, four guide rails are distributed in an annular array relative to the central axis of the needle tube, and arc-shaped through holes and rectangular through holes matched with the sliding strips and the limiting strips are formed in the middle of one side, away from the inner wall of the needle tube, of each guide rail.
Further, four the spliced pole is from last to being equidistant distribution down in proper order, the size of first groove of keeping away and the size of second groove of keeping away all is greater than the size of straw.
Furthermore, the movable rod is in sliding connection with the fixed cylinder, and one end, far away from the sliding block, of the spring is fixed to the inner wall of the fixed cylinder.
Further, the straw communicates with the compression ball, the crossing department of straw and syringe needle is provided with slope and not with first clearance groove contact, the bottom of straw and the bottom of syringe needle run through the second in proper order and keep away dead slot, second through-hole and first clearance groove, and the syringe needle runs through first through-hole and waist and pierces the needle, the lateral wall and the universal ball of straw are sliding connection, the syringe needle does not contact with the universal ball.
(III) advantageous effects
Compared with the prior art, the utility model has the beneficial effects that: this device for tumor tissue transplantation:
(1) through seting up the internal thread groove in the bottom of needle tubing to at the internal thread groove's internal thread connection lower screw cap and at needle tubing top threaded connection upper screw cap, and through slide rail sliding connection guider inside the needle tubing, conveniently dismantle and disinfect to the needle tubing like this, also can change upper screw cap and lower screw cap as required simultaneously, make the device can adapt to not unidimensional straw, improved work efficiency, save the resource.
(2) The guide device is arranged inside the guide rail, so that the suction tubes of different sizes extrude the universal ball through the suction tubes when being inserted into the needle tubes, the movable rod can move in the fixed cylinder, the spring is compressed through the sliding block, the universal ball can be always in contact with the suction tubes under the action of the spring, the phenomenon that tumor tissues are polluted due to the contact of an injection needle head and the needle tubes is avoided, and the working efficiency is improved.
Drawings
FIG. 1 is a schematic perspective view of a tumor tissue transplantation device according to the present invention;
FIG. 2 is a schematic longitudinal sectional view showing a device for tumor tissue transplantation according to the present invention;
FIG. 3 is an enlarged schematic view of the tumor tissue transplantation device of the present invention at A in FIG. 2;
FIG. 4 is an enlarged view of the device for tumor tissue transplantation of the present invention shown at B in FIG. 2;
FIG. 5 is a cross-sectional view schematically showing the structure of the device for tumor tissue transplantation of the present invention;
FIG. 6 is a perspective view of a guide device of the device for tumor tissue transplantation according to the present invention;
FIG. 7 is an enlarged schematic view of the tumor tissue transplantation device of the present invention at C in FIG. 6.
In the figure: 1. a needle tube; 2. an internal thread groove; 3. a lower threaded cap; 4. a guide rail; 5. a first clearance groove; 6. puncturing the waist; 7. a slide bar; 8. a limiting strip; 9. a fixed cylinder; 10. a slider; 11. a movable rod; 12. a universal ball; 13. a spring; 14. a screw cap is arranged; 15. a second clearance groove; 16. an internal thread; 17. a straw; 18. compressing the ball; 19. an injection needle; 20. connecting columns.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to FIGS. 1-7, the present invention provides a device for tumor tissue transplantation; comprises a needle tube 1, the bottom of the needle tube 1 is connected with a lower thread cover 3 by screw thread, the middle part of the upper surface of the lower thread cover 3 is provided with a first clearance groove 5, the middle part of the inner wall of the first clearance groove 5 is provided with a first through hole, the middle part of the lower surface of the lower thread cover 3 is fixed with a lumbar puncture needle 6, the top of the needle tube 1 is connected with an upper thread cover 14 by screw thread, the middle part of the upper surface of the upper thread cover 14 is provided with a second clearance groove 15, the middle part of the inner bottom wall of the second clearance groove 15 is provided with a second through hole, the inner wall of the needle tube 1 is fixed with four guide rails 4, the inner part of each guide rail 4 is connected with a slide bar 7 in a sliding way, one side of each slide bar 7 far away from the inner wall of the needle tube 1 is fixed with a limit bar 8, one side of each limit bar 8 far away from the slide bar 7 is fixed with a connecting column 20, one side of the connecting column 20 far away from the limit bar 8 is fixed with a fixed cylinder 9, the inner part of the fixed cylinder 9 is connected with a slide block 10, one side of the slide block 10 is fixed with a movable rod 11, a spring 13 is fixed on the other side of the slider 10, a universal ball 12 is fixed on one end of the movable rod 11, which is far away from the slider 10, a suction tube 17 is arranged in the needle tube 1, a compression ball 18 is fixed on the top of the suction tube 17, an injection needle 19 is fixed on the bottom of the suction tube 17, and a guide device is arranged in the guide rail 4, so that the universal ball 12 is extruded through the suction tube 17 when the suction tubes 17 with different sizes are inserted into the needle tube 1, the movable rod 11 can move in the fixed cylinder 9, meanwhile, the movable rod 11 compresses the spring 13 through the slider 10, the universal ball 12 can be always contacted with the suction tube 17 under the action of the spring 13, the phenomenon that the injection needle 19 is contacted with the needle tube 1 to cause the tumor tissue to be polluted is avoided, and the working efficiency is improved;
as a preferred technical scheme of the utility model: the middle part of the lower surface of the needle tube 1 is provided with an internal thread groove 2, the outer side of the upper end of the lower thread cover 3 is provided with an external thread ring matched with the internal thread groove 2, the inner wall of the upper end of the needle tube 1 is provided with an internal thread 16 matched with the upper thread cover 14, and the top and the bottom of the guide rail 4 are respectively contacted with the lower surface of the upper thread cover 14 and the upper surface of the lower thread cover 3, so that the upper thread cover 14 and the lower thread cover 3 can better limit the guide rail 4 and the slide bar 7;
as a preferred technical scheme of the utility model: the lumbar puncture needle 6 is communicated with the first through hole, and the second through hole is opposite to the first through hole, so that the suction tube 17 and the injection needle 19 can enter the needle tube 1 more smoothly;
as a preferred technical scheme of the utility model: the four guide rails 4 are distributed in an annular array relative to the central axis of the needle tube 1, and arc-shaped through holes and rectangular through holes matched with the sliding strips 7 and the limiting strips 8 are formed in the middle of one side of each guide rail 4, which is far away from the inner wall of the needle tube 1, so that the guide rails 4 can better guide and limit the sliding strips 7 and the limiting strips 8;
as a preferred technical scheme of the utility model: the four connecting columns 20 are distributed at equal intervals from top to bottom in sequence, the size of the first clearance groove 5 and the size of the second clearance groove 15 are both larger than the size of the suction pipe 17, and the first clearance groove 5 and the second clearance groove 15 are arranged to prevent the injection needle 19 from contacting the upper threaded cover 14 and the lower threaded cover 3 and have a guiding function;
as a preferred technical scheme of the utility model: the movable rod 11 is connected with the fixed cylinder 9 in a sliding manner, and one end of the spring 13, which is far away from the slide block 10, is fixed with the inner wall of the fixed cylinder 9, so that the movable rod 11 can drive the universal ball 12 to be always contacted with the suction pipe 17 under the action of the spring 13;
as a preferred technical scheme of the utility model: the suction pipe 17 is communicated with the compression ball 18, a slope is arranged at the intersection of the suction pipe 17 and the injection needle 19 and does not contact with the first clearance groove 5, the bottom of the suction pipe 17 and the bottom of the injection needle 19 sequentially penetrate through the second clearance groove 15, the second through hole and the first clearance groove 5, the injection needle 19 penetrates through the first through hole and the lumbar puncture needle 6, the outer side wall of the suction pipe 17 is in sliding connection with the universal ball 12, the injection needle 19 does not contact with the universal ball 12, and the suction pipe 17 and the injection needle 19 can smoothly enter the needle tube 1 and the lumbar puncture needle 6.
The working principle of the embodiment is as follows: when the device for tumor tissue transplantation is used, as shown in fig. 1-7, the device integrally comprises a needle tube 1, an inner thread groove 2, a lower thread cover 3, a guide rail 4, a first clearance groove 5, a lumbar puncture needle 6, a slide bar 7, a limit strip 8, a fixed cylinder 9, a slide block 10, a movable rod 11, a universal ball 12, a spring 13, an upper thread cover 14, a second clearance groove 15, an inner thread 16, a suction tube 17, a compression ball 18, an injection needle 19 and a connecting column 20, when in use, the proper upper thread cover 14 and lower thread cover 3 can be selected according to the size of the suction tube 17 and the size of the injection needle 19, the lower thread cover 3 is screwed into the bottom of the needle tube 1, the upper surface of the lower thread cover 3 is abutted against the lower surface of the guide rail 4, then the slide bar 7 and the limit strip 8 on the guide device are installed into the guide rail 4, so that the bottom of the slide bar 7 is contacted with the upper surface of the lower thread cover 3, then screwing the upper thread cover 14 into the top of the needle tube 1, wherein the lower surface of the upper thread cover 14 is pressed against the guide rail 4 and the slide bar 7, then compressing the compression ball 18, so that the tissue block is fixed at the end part of the injection needle 19 by the adsorption force generated by the compression ball 18, holding the lumbar puncture needle 6 by hand, puncturing the lumbar puncture needle 6 at the lower part of the skin, moving the compression ball head 18 downwards, driving the suction pipe 17 and the injection needle 19 to move downwards, enabling the suction pipe 17 and the injection needle 19 to sequentially pass through the second clearance groove 15 and the second through hole and enter the interior of the needle tube 1, at the moment, because the size of the injection needle 19 is smaller than the size among the four universal balls 12, the tumor tissue cannot contact with the universal balls 12, but the size of the suction pipe 17 is larger than the size of the injection needle 19, enabling the outer wall of the suction pipe 17 to contact with the universal balls 12 and extrude the universal balls 12, enabling the universal balls 12 to drive the movable rod 11 to move towards the fixed barrel 9, at the same time, the movable rod 11 drives the slider 10 to move and press the spring 13, so as to move the compression ball 18 downwards all the time, thus making the injection needle 19 pass through the first clearance groove 5 and the first through hole and enter the interior of the lumbar puncture needle 6, so that the tissue mass is directly implanted into the lower part of the skin, which is the working process of the whole device, and the content which is not described in detail in the specification belongs to the prior art which is well known to the professional skilled in the art.
Although the present invention has been described in detail with reference to the foregoing embodiments, it should be noted that, in the present invention, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," "fixed," and the like are to be construed broadly, and for example, may be fixedly connected or detachably connected; or indirectly through an intermediary. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations; it will be apparent to those skilled in the art that modifications and equivalents may be made in the embodiments and/or portions thereof without departing from the spirit and scope of the present invention.

Claims (7)

1. The device for tumor tissue transplantation comprises a needle tube (1) and is characterized in that the bottom of the needle tube (1) is in threaded connection with a lower threaded cover (3), a first clearance groove (5) is formed in the middle of the upper surface of the lower threaded cover (3), a first through hole is formed in the middle of the inner wall of the first clearance groove (5), a waist penetrating needle (6) is fixed in the middle of the lower surface of the lower threaded cover (3), an upper threaded cover (14) is in threaded connection with the top of the needle tube (1), a second clearance groove (15) is formed in the middle of the upper surface of the upper threaded cover (14), a second through hole is formed in the middle of the inner bottom wall of the second clearance groove (15), four guide rails (4) are fixed on the inner wall of the needle tube (1), sliding strips (7) are slidably connected inside the guide rails (4), and a limiting strip (8) is fixed on one side, far away from the inner wall of the needle tube (1), of each sliding strip (7), every one side that draw runner (7) were kept away from in spacing strip (8) all is fixed with spliced pole (20), one side that spacing strip (8) were kept away from in spliced pole (20) is fixed with solid fixed cylinder (9), the inside sliding connection of solid fixed cylinder (9) has slider (10), one side of slider (10) is fixed with movable rod (11), the opposite side of slider (10) is fixed with spring (13), the one end that slider (10) were kept away from in movable rod (11) is fixed with universal ball (12), the inside of needle tubing (1) is provided with straw (17), the top of straw (17) is fixed with compression ball (18), the bottom of straw (17) is fixed with injection needle (19).
2. The device for tumor tissue transplantation according to claim 1, wherein an internal thread groove (2) is formed in the middle of the lower surface of the needle tube (1), an external thread ring matched with the internal thread groove (2) is formed on the outer side of the upper end of the lower thread cover (3), an internal thread (16) matched with the upper thread cover (14) is formed on the inner wall of the upper end of the needle tube (1), and the top and the bottom of the guide rail (4) are respectively in contact with the lower surface of the upper thread cover (14) and the upper surface of the lower thread cover (3).
3. The device for tumor tissue transplantation according to claim 1, wherein the lumbar puncture needle (6) is in communication with the first through hole, and the second through hole is opposite to the first through hole.
4. The device for tumor tissue transplantation according to claim 1, wherein the four guide rails (4) are distributed in an annular array about a central axis of the needle tube (1), and arc-shaped through holes and rectangular through holes matched with the sliding strips (7) and the limiting strips (8) are formed in the middle of one side of the guide rails (4) far away from the inner wall of the needle tube (1).
5. The device for tumor tissue transplantation according to claim 1, wherein the four connecting columns (20) are sequentially distributed at equal intervals from top to bottom, and the size of the first clearance groove (5) and the size of the second clearance groove (15) are both larger than the size of the suction tube (17).
6. The device for tumor tissue transplantation according to claim 1, wherein the movable rod (11) is slidably connected to the fixed cylinder (9), and one end of the spring (13) away from the slider (10) is fixed to the inner wall of the fixed cylinder (9).
7. The device for tumor tissue transplantation according to claim 1, wherein the suction tube (17) is communicated with the compression ball (18), a slope is arranged at the intersection of the suction tube (17) and the injection needle (19) and is not in contact with the first clearance groove (5), the bottom of the suction tube (17) and the bottom of the injection needle (19) sequentially penetrate through the second clearance groove (15), the second through hole and the first clearance groove (5), the injection needle (19) penetrates through the first through hole and the lumbar puncture needle (6), the outer side wall of the suction tube (17) is in sliding connection with the universal ball (12), and the injection needle (19) is not in contact with the universal ball (12).
CN202121347771.XU 2021-06-17 2021-06-17 Device for tumor tissue transplantation Active CN215914703U (en)

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CN202121347771.XU CN215914703U (en) 2021-06-17 2021-06-17 Device for tumor tissue transplantation

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CN202121347771.XU CN215914703U (en) 2021-06-17 2021-06-17 Device for tumor tissue transplantation

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116159197A (en) * 2023-03-13 2023-05-26 牡丹江医学院 Child sputum aspirator capable of preventing pollution from being scattered outwards

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116159197A (en) * 2023-03-13 2023-05-26 牡丹江医学院 Child sputum aspirator capable of preventing pollution from being scattered outwards

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