CN219032186U - Stem cell extraction device - Google Patents
Stem cell extraction device Download PDFInfo
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- CN219032186U CN219032186U CN202223454655.5U CN202223454655U CN219032186U CN 219032186 U CN219032186 U CN 219032186U CN 202223454655 U CN202223454655 U CN 202223454655U CN 219032186 U CN219032186 U CN 219032186U
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Abstract
The utility model discloses a stem cell extraction device, comprising: one end of the needle cylinder is fixedly connected with a one-way component, one end of the one-way component, which is far away from the needle cylinder, is fixedly connected with a needle head, the needle head and the needle cylinder are communicated with the one-way component, a piston is connected in the needle cylinder in a sliding way, one end of the piston, which is far away from the needle head, is fixedly connected with a push rod, and the tail end of the push rod penetrates through the needle cylinder; the one-way filter assembly is fixedly connected to the outer side wall of the needle cylinder, is communicated with the needle cylinder and is positioned at one side of the needle cylinder close to the needle head; the sampling tube is sleeved outside the unidirectional filtering component; clamping components are symmetrically arranged on two sides of the unidirectional filtering component, the clamping components are fixedly connected with the outer wall of the needle cylinder, and the clamping components are used for clamping the sampling tube. The utility model can realize continuous stem cell extraction until the required amount of stem cells are obtained, and simultaneously can directly split the extracted stem cells into the sampling tube, thereby facilitating the centrifugal treatment in the later stage.
Description
Technical Field
The utility model relates to the technical field of stem cell extraction, in particular to a stem cell extraction device.
Background
Stem cells refer to primitive cells having self-renewing and multipotent differentiation potential, which are cells of origin of the body, and which can differentiate into one or more cells constituting tissues or organs of the human body under specific conditions. Self-renewal refers to the ability of stem cells to maintain the size of a stem cell population by cell division; multidirectional differentiation means that stem cells have plasticity and can differentiate into different tissue cells under different environments so as to form various complex tissue organs of an organism.
In the treatment of certain diseases, stem cells are required to be extracted from the body of a healthy person for transplantation into the body of a patient, and currently, stem cell puncture extraction is mainly performed by adopting a sampling device similar to a syringe injector, but because the amount of liquid containing the stem cells extracted by the sampling device at one time is limited, when the required amount is large, the stem cells are required to be extracted by multiple punctures, so that the injury to a punctured person is increased.
Therefore, there is a need to design stem cell extraction devices to solve the above problems.
Disclosure of Invention
The present utility model provides a stem cell extraction device comprising:
the needle cylinder comprises a needle cylinder body, wherein one end of the needle cylinder is fixedly connected with a unidirectional component, one end of the unidirectional component, which is far away from the needle cylinder, is fixedly connected with a needle head, the needle head and the needle cylinder are both communicated with the unidirectional component, a piston is connected in the needle cylinder in a sliding way, one end of the piston, which is far away from the needle head, is fixedly connected with a push rod, and the tail end of the push rod penetrates through the needle cylinder;
the one-way filter assembly is fixedly connected to the outer side wall of the needle cylinder, the one-way filter assembly is communicated with the needle cylinder, and the one-way filter assembly is positioned on one side of the needle cylinder, which is close to the needle head;
the sampling tube is sleeved outside the unidirectional filtering component;
the clamping assembly is symmetrically arranged on two sides of the unidirectional filtering assembly and fixedly connected with the outer wall of the needle cylinder, and the clamping assembly is used for clamping the sampling tube.
Preferably, the unidirectional filtering component comprises a second valve body, a second valve core and a filter membrane, wherein the second valve body is fixedly connected to the outer side wall of the needle cylinder, the second valve body is positioned on one side, close to the needle head, of the needle cylinder, a second channel is formed in the second valve body, the second channel is communicated with the needle cylinder, the second valve core is positioned in the second channel, the large diameter of the second valve core is smaller than that of the second channel, a second sliding groove is formed in the inner wall of the second channel, a second sliding block is slidably connected in the second sliding groove, the second sliding block is fixedly connected with the second valve core, a second spring is fixedly connected to one side, far away from the needle cylinder, of the second sliding block, the tail end of the second spring is fixedly connected with the second sliding groove, a through hole is formed in the bottom end of the second valve body, the through hole is communicated with the second channel, and the filter membrane is fixedly connected in the through hole.
Preferably, the clamping assembly comprises a fixed block, clamping plates and a screw rod, wherein the fixed block is fixedly connected to the outer side wall of the needle cylinder, the clamping plates are located on one side, close to the second valve body, of the fixed block, screw threads penetrate through the fixed block and are rotationally connected with the clamping plates, guide rods are symmetrically arranged on two sides of the screw rod, the guide rods penetrate through the fixed block in a sliding mode, and the guide rods are fixedly connected with the clamping plates.
Preferably, a flexible gasket is fixedly connected to one side of the clamping plate, which is close to the second valve body.
Preferably, the unidirectional assembly comprises a first valve body and a first valve core, the first valve body is fixedly connected with one end of the needle cylinder, the needle head is fixedly connected with one end of the first valve body away from the needle cylinder, a first channel is formed in the first valve body, the needle head and the needle cylinder are communicated with the first channel, the first valve core is located in the first channel, the large diameter of the first valve core is smaller than that of the first channel, a first sliding groove is formed in the inner wall of the first channel, a first sliding block is connected in the first sliding groove in a sliding mode, the first sliding block is fixedly connected with the first valve core, a first spring is fixedly connected to one side of the first sliding block, which is close to the needle cylinder, and the tail end of the first spring is fixedly connected with the first sliding groove.
Preferably, the outer side wall of the needle cylinder is fixedly connected with a plurality of fixed handles.
Preferably, the sampling tube is carved with scales.
The utility model discloses the following technical effects:
according to the utility model, the unidirectional component and the unidirectional filtering component are arranged and are matched with the detachable sampling tube, so that continuous stem cell extraction can be realized until the required amount of stem cells are obtained, and meanwhile, the extracted stem cells can be directly packaged into the sampling tube, thereby facilitating later centrifugation.
Drawings
In order to more clearly illustrate the embodiments of the present utility model or the technical solutions of the prior art, the drawings that are needed in the embodiments will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present utility model, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of a stem cell extraction device according to the present utility model;
FIG. 2 is an enlarged view of A in FIG. 1;
FIG. 3 is an enlarged view of B in FIG. 1;
FIG. 4 is a schematic structural view of a sampling tube;
wherein, 1, the needle head; 2. a needle cylinder; 3. a piston; 4. a push rod; 5. a fixed handle; 6. a sampling tube; 7. a first valve body; 8. a first valve core; 9. a first slider; 10. a first spring; 11. a first channel; 12. a filter membrane; 13. a second valve body; 14. a second spring; 15. a second slider; 16. a second valve core; 17. a flexible gasket; 18. a clamping plate; 19. a guide rod; 20. a fixed block; 21. a screw; 22. and a second channel.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
In order that the above-recited objects, features and advantages of the present utility model will become more readily apparent, a more particular description of the utility model will be rendered by reference to the appended drawings and appended detailed description.
The present utility model provides a stem cell extraction device comprising:
the needle cylinder 2, one end of the needle cylinder 2 is fixedly connected with a one-way component, one end of the one-way component, which is far away from the needle cylinder 2, is fixedly connected with a needle head 1, both the needle head 1 and the needle cylinder 2 are communicated with the one-way component, a piston 3 is connected in the needle cylinder 2 in a sliding manner, one end of the piston 3, which is far away from the needle head 1, is fixedly connected with a push rod 4, and the tail end of the push rod 4 penetrates through the needle cylinder 2;
the one-way filter component is fixedly connected to the outer side wall of the needle cylinder 2, the one-way filter component is communicated with the needle cylinder 2, and the one-way filter component is positioned at one side of the needle cylinder 2 close to the needle head 1;
the sampling tube 6 is sleeved outside the unidirectional filter component;
clamping components are symmetrically arranged on two sides of the unidirectional filtering component, the clamping components are fixedly connected with the outer wall of the needle cylinder 2, and the clamping components are used for clamping the sampling tube 6.
Through setting up one-way subassembly and one-way filtration subassembly to cooperate detachable sampling tube 6, can realize continuous stem cell and draw, until obtaining the stem cell of required volume, can also directly divide into the sampling tube 6 with the stem cell of drawing simultaneously, make things convenient for the later stage to carry out centrifugal treatment.
Further, the unidirectional filter component comprises a second valve body 13, a second valve core 16 and a filter membrane 12, wherein the second valve body 13 is fixedly connected to the outer side wall of the needle cylinder 2, the second valve body 13 is positioned at one side of the needle cylinder 2, which is close to the needle head 1, a second channel 22 is formed in the second valve body 13, the second channel 22 is communicated with the needle cylinder 2, the second valve core 16 is positioned in the second channel 22, the large diameter of the second valve core 16 is smaller than that of the second channel 22, a second sliding groove is formed in the inner wall of the second channel 22, a second sliding block 15 is slidingly connected in the second sliding groove, the second sliding block 15 is fixedly connected with the second valve core 16, a second spring 14 is fixedly connected to one side, which is far away from the needle cylinder 2, of the second sliding block 15, the tail end of the second spring 14 is fixedly connected with the second sliding groove, a through hole is formed in the bottom end of the second valve body 13, the through hole is communicated with the second channel 22, and the filter membrane 12 is fixedly connected in the through hole.
When the push rod 4 drives the piston 3 to push to one side close to the needle head 1, the one-way component is sealed, and the space pressure intensity in the needle cylinder 2, which is positioned on one side of the piston 3 close to the needle head 1, is increased, so that the second valve core 16 is pushed and the second spring 14 is compressed, so that the second valve core 16 moves to a direction far away from the needle cylinder 2, and the liquid containing stem cells in the needle cylinder 2 enters the sampling tube 6 along the second channel 22 and through the filter membrane 12, and the filter membrane 12 can prevent skin and meat tissues possibly remained in the solution from entering the sampling tube 6, so that a better stem cell extraction effect is achieved.
Further, the second channel 22 is composed of a truncated cone-shaped structure and a cylindrical structure, the truncated cone-shaped structure is located at one side close to the needle cylinder 2, the small diameter end of the truncated cone-shaped structure is located at one side close to the needle cylinder 2, and the second sliding groove is formed in the cylindrical structure.
Further, the clamping assembly comprises a fixed block 20, clamping plates 18 and a screw rod 21, wherein the fixed block 20 is fixedly connected to the outer side wall of the needle cylinder 2, the clamping plates 18 are located on one side, close to the second valve body 13, of the fixed block 20, the screw rod 21 penetrates through the fixed block 20 in a threaded mode and is rotationally connected with the clamping plates 18, guide rods 19 are symmetrically arranged on two sides of the screw rod 21, the guide rods 19 penetrate through the fixed block 20 in a sliding mode, and the guide rods 19 are fixedly connected with the clamping plates 18.
When the screw rod 21 is rotated, due to the screw rod 21 is in threaded connection with the fixed block 20, and due to the limiting effect of the sliding connection of the guide rod 19 and the fixed block 20, the screw rod 21 and the fixed block 20 can move relatively, and further the clamping plate 18 is driven to move towards the direction close to the second valve body 13 or away from the second valve body 13, so that the clamping or loosening of the sampling tubes 6 is realized, when a proper amount of liquid containing stem cells is stored in one sampling tube 6, the clamping plate 18 does not clamp the sampling tube 6 any more, the sampling tube 6 is taken down, a new sampling tube 6 is replaced, and the sampling tube 6 is clamped and fixed through the clamping plate 18.
Further, a flexible gasket 17 is fixedly connected to one side of the clamping plate 18, which is close to the second valve body 13.
Further, the one-way subassembly includes first valve body 7 and first case 8, the one end at cylinder 2 is fixedly connected to first valve body 7, needle 1 rigid coupling is kept away from the one end of cylinder 2 at first valve body 7, first passageway 11 has been seted up in the first valve body 7, needle 1 and cylinder 2 all communicate with first passageway 11, first case 8 is located first passageway 11, the major diameter of first case 8 is less than the major diameter of first passageway 11, first spout has been seted up to first passageway 11 inner wall, sliding connection has first slider 9 in the first spout, first slider 9 and first case 8 rigid coupling, one side rigid coupling that first slider 9 is close to cylinder 2 has first spring 10, first spring 10 end and first spout rigid coupling.
When an operator drives the piston 3 to move in the direction away from the needle head 1 by the push rod 4, the space pressure in the needle cylinder 2, which is positioned on one side of the piston 3, close to the needle head 1 is increased, the first valve core 8 compresses the first spring 10 to move in the direction close to the piston 3, the first channel 11 is opened, and then the liquid containing stem cells can flow into the needle cylinder 2 from the needle head 1, when the push rod 4 drives the piston 3 to push to one side close to the needle head 1, the space pressure in the needle cylinder 2, which is positioned on one side of the piston 3, close to the needle head 1 is increased, the first valve core 8 seals the first channel 11, at the moment, the second valve core 16 in the second channel 22 is opened, the liquid containing stem cells can enter the sampling tube 6 through the second channel 22, continuous stem cell extraction can be realized through the arrangement of the one-way assembly and the one-way filter assembly until the stem cells with required quantity are obtained, and meanwhile, the extracted stem cells can be directly packaged into the sampling tube 6, so that the post centrifugation treatment is convenient.
Further, the first channel 11 is composed of a truncated cone-shaped structure and a cylindrical structure, the truncated cone-shaped structure is located at one side far away from the needle cylinder 2, the small diameter end of the truncated cone-shaped structure is located at one side far away from the needle cylinder 2, and the first sliding groove is formed in the cylindrical structure.
Furthermore, in order to better press and pull the push rod 4 by an operator, a plurality of fixed handles 5 are fixedly connected to the outer side wall of the needle cylinder 2.
Further, the sampling tube 6 is marked with graduations.
The using method comprises the following steps: the sampling tube 6 is clamped and fixed by the clamping component, the needle head 1 is inserted into the part of stem cells to be extracted, the one-way component of the push rod 4 is pulled to open, liquid containing the stem cells enters the needle cylinder 2, the push rod 4 is pushed after a certain amount of the liquid is extracted, the one-way component is closed, the one-way filtering component is opened, the liquid containing the stem cells enters the sampling tube 6 through the filtering of the filter membrane 12, the sampling tube 6 is taken down after the liquid in one sampling tube 6 reaches a certain amount, and then the sampling tube 6 is replaced by a new sampling tube 6.
In the description of the present utility model, it should be understood that the terms "longitudinal," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present utility model, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present utility model.
The above embodiments are only illustrative of the preferred embodiments of the present utility model and are not intended to limit the scope of the present utility model, and various modifications and improvements made by those skilled in the art to the technical solutions of the present utility model should fall within the protection scope defined by the claims of the present utility model without departing from the design spirit of the present utility model.
Claims (7)
1. Stem cell extraction device, characterized by comprising:
the needle comprises a needle cylinder (2), wherein one end of the needle cylinder (2) is fixedly connected with a one-way component, one end of the one-way component, which is far away from the needle cylinder (2), is fixedly connected with a needle head (1), the needle head (1) and the needle cylinder (2) are both communicated with the one-way component, a piston (3) is connected in a sliding manner in the needle cylinder (2), one end of the piston (3), which is far away from the needle head (1), is fixedly connected with a push rod (4), and the tail end of the push rod (4) penetrates through the needle cylinder (2);
the one-way filter assembly is fixedly connected to the outer side wall of the needle cylinder (2), the one-way filter assembly is communicated with the needle cylinder (2), and the one-way filter assembly is positioned on one side of the needle cylinder (2) close to the needle head (1);
the sampling tube (6) is sleeved outside the unidirectional filtering component;
the clamping assembly is symmetrically arranged on two sides of the unidirectional filtering assembly and fixedly connected with the outer wall of the needle cylinder (2), and the clamping assembly is used for clamping the sampling tube (6).
2. The stem cell extraction apparatus of claim 1, wherein: the one-way filter assembly comprises a second valve body (13), a second valve core (16) and a filter membrane (12), wherein the second valve body (13) is fixedly connected to the outer side wall of the needle cylinder (2), the second valve body (13) is positioned on one side, close to the needle head (1), of the needle cylinder (2), a second channel (22) is formed in the second valve body (13), the second channel (22) is communicated with the needle cylinder (2), the second valve core (16) is positioned in the second channel (22), the large diameter of the second valve core (16) is smaller than that of the second channel (22), a second chute is formed in the inner wall of the second channel (22), a second slider (15) is connected in a sliding mode in the second chute, a second spring (14) is fixedly connected to one side, far away from the second valve core (2), of the second slider (15) is fixedly connected to the end of the second spring (14), the second chute (13) is fixedly connected to the bottom end of the needle cylinder (12), and the filter membrane (12) is fixedly connected to the bottom end of the needle cylinder (12).
3. The stem cell extraction apparatus of claim 2, wherein: the clamping assembly comprises a fixed block (20), clamping plates (18) and a screw rod (21), wherein the fixed block (20) is fixedly connected to the outer side wall of the needle cylinder (2), the clamping plates (18) are located on one side, close to the second valve body (13), of the fixed block (20), the screw rod (21) penetrates through threads of the screw rod (21) and is rotationally connected with the clamping plates (18), guide rods (19) are symmetrically arranged on two sides of the screw rod (21), the guide rods (19) penetrate through the fixed block (20) in a sliding mode, and the guide rods (19) are fixedly connected with the clamping plates (18).
4. A stem cell extraction apparatus according to claim 3, wherein: and one side of the clamping plate (18) close to the second valve body (13) is fixedly connected with a flexible gasket (17).
5. The stem cell extraction apparatus of claim 1, wherein: the one-way assembly comprises a first valve body (7) and a first valve core (8), wherein the first valve body (7) is fixedly connected to one end of the needle cylinder (2), the needle head (1) is fixedly connected to the first valve body (7) and is far away from one end of the needle cylinder (2), a first channel (11) is formed in the first valve body (7), the needle head (1) and the needle cylinder (2) are communicated with the first channel (11), the first valve core (8) is located in the first channel (11), the large diameter of the first valve core (8) is smaller than that of the first channel (11), a first sliding groove is formed in the inner wall of the first channel (11), a first sliding block (9) is connected to the first sliding groove in a sliding mode, a first spring (10) is fixedly connected to one side, close to the first sliding block (9), of the first sliding block (2), and the tail end of the first spring (10) is fixedly connected with the first sliding groove.
6. The stem cell extraction apparatus of claim 1, wherein: the outer side wall of the needle cylinder (2) is fixedly connected with a plurality of fixed handles (5).
7. The stem cell extraction apparatus of claim 1, wherein: the sampling tube (6) is carved with scales.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223454655.5U CN219032186U (en) | 2022-12-23 | 2022-12-23 | Stem cell extraction device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223454655.5U CN219032186U (en) | 2022-12-23 | 2022-12-23 | Stem cell extraction device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219032186U true CN219032186U (en) | 2023-05-16 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202223454655.5U Active CN219032186U (en) | 2022-12-23 | 2022-12-23 | Stem cell extraction device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219032186U (en) |
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2022
- 2022-12-23 CN CN202223454655.5U patent/CN219032186U/en active Active
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