CN215833102U - Gather full-automatic pelleter of liquid-based cell - Google Patents

Gather full-automatic pelleter of liquid-based cell Download PDF

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CN215833102U
CN215833102U CN202121899506.2U CN202121899506U CN215833102U CN 215833102 U CN215833102 U CN 215833102U CN 202121899506 U CN202121899506 U CN 202121899506U CN 215833102 U CN215833102 U CN 215833102U
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clamping
slide
sucking disc
funnel
bin
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姚香怡
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Abstract

The utility model provides a full-automatic pelleter for collecting liquid-based cells, which comprises a frame main body, wherein the frame main body internally comprises a stirring mechanism, a vibrating mechanism, a clamping and rotating mechanism, a funnel lifting mechanism, a clamping and overturning mechanism, a sucker, a clamping and rotating mechanism, a slide bin lifting mechanism and a slide conveying mechanism; the stirring mechanism is used for carrying out primary shaking treatment on the cell liquid box; the oscillation mechanism is used for carrying out secondary oscillation treatment on the cell liquid box subjected to primary shaking-up treatment; and the clamping and rotating mechanism is used for clamping and rotating the cell liquid box after the secondary oscillation treatment to open the cover. Meanwhile, the device is formed by assembling a plurality of mechanisms, when a specific mechanism is abnormal, the specific mechanism can be detached and replaced independently, the maintenance time of the whole device is short, the assembly and the disassembly are convenient, and the abnormality is conveniently checked. In addition, the sucking disc and the clamping mechanism can overcome the thin and fragile characteristic of the glass slide, and the sucking disc is used for drawing or releasing the pressure, so that the process of safe operation of sucking and releasing the glass slide by the sucking disc can be realized.

Description

Gather full-automatic pelleter of liquid-based cell
Technical Field
The utility model belongs to the technical field of equipment for manufacturing a slide after cell sampling, and particularly relates to a full-automatic sheet making machine for collecting liquid-based cells.
Background
The liquid-based cytology examination adopts a liquid-based cytology slide making and staining technology to detect exfoliated cells of cervix uteri and other parts and carry out cytology diagnosis, is a more advanced cytology examination technology in the world at present, and aiming at the field of exfoliated cells of the cervix uteri, the technology obviously improves the satisfaction degree of a sample and the detection rate of abnormal cells of the cervix uteri compared with the traditional pap smear examination. At present, the liquid-based cytology smear making technology is a technology for storing exfoliated cells in liquid and uniformly dispersing and attaching the cells on a glass slide through a special way to make a smear. The liquid-based cytology slide-making technology is born in developed countries such as the United states in 1991, is applied to gynecological cytology examination first, and is researched for screening cervical cancer through liquid-based cytology from 2001 in China, so that the technology is developed rapidly, and great contribution is made to exfoliative cytology diagnosis.
The traditional liquid-based cytology film-making technology comprises a film filtration thin-layer film-making technology (TCT), an automatic centrifugal sedimentation film-making technology (LCT), a centrifugal flail film-making technology and a sharp manual centrifugal smear technology (LPT). These film-making techniques have the defects of expensive equipment, high cost of reagent consumables, low positive rate, unstable quality and the like, and simultaneously, the automation degree of most of designs is not high enough, and machines need manual operation in the operation process, and the design volume of the whole machine is huge, and the guidance quality is poor, and the precision of the film-making can be influenced after long-term use. In the face of large amount of hospital sampling, the precision of manual operation is limited, and the workload is very large, so that the requirement of the industry on a full-automatic pelleter is promoted, and the improvement is really necessary.
Disclosure of Invention
The technical scheme is as follows: in order to solve the technical problem, the utility model provides a full-automatic pelleter for collecting liquid-based cells, and particularly relates to a full-automatic pelleter for collecting liquid-based cells
The glass slide taking device comprises a frame main body, wherein the frame main body internally comprises a stirring mechanism, a vibrating mechanism, a clamping and rotating mechanism, a funnel lifting mechanism, a clamping and overturning mechanism, a sucker, a clamping and overturning mechanism, a glass slide bin lifting mechanism and a slide conveying mechanism;
the stirring mechanism is used for mechanically shaking the cell liquid box and primarily shaking up the cell liquid box;
the vibrating mechanism is fixedly arranged on one side of the stirring mechanism, and secondary vibrating treatment is carried out on the cell liquid box after primary shaking treatment;
the clamping and rotating mechanism is arranged on one side of the oscillating mechanism and is used for clamping the cell liquid box after secondary oscillation treatment and rotationally opening the cover;
the funnel lifting mechanism is used for lifting the disposable funnel and automatically supplementing the height of the disposable funnel after the disposable funnel is taken away;
the clamping and overturning mechanism is arranged on one side of the clamping and overturning mechanism and is used for clamping and overturning the cell liquid box of the rotary cover and pouring the cell liquid into a station;
one end of the sucking disc and clamping mechanism is fixedly arranged on the frame main body, and the other end of the sucking disc and clamping mechanism is provided with a moving mechanism and a sucking disc in three-dimensional directions and used for sucking and moving a slide, a slide bin, a mold pressing plate and a disposable funnel;
the glass bin lifting mechanism is arranged on one side of the sucking disc and the clamping mechanism and is used for lifting a group of glass bins at a time and automatically supplementing and taking the height of the glass bins away;
the piece feeding mechanism is arranged on one side of the sucking disc and the clamping mechanism and used for fixedly clamping the slide and the die pressing plate.
As an improvement, the device also comprises a slide storage bin and a mould pressing plate bin;
the slide storage bin is used for storing slides, and when the sucking disc and the clamping mechanism suck the slides, the height of the slide storage bin can be automatically supplemented to the height before the slides are not sucked;
the mould pressing plate bin is used for storing the mould pressing plates and used mould pressing plates.
As an improvement, the sucker and clamping mechanism comprises a Y-axis slide rail, an X-axis slide rail, a Z-axis slide rail, a sucker assembly and a clamping assembly;
the Y-axis slide rails are arranged in two groups and are fixedly arranged on the two side frames of the frame main body at intervals and symmetrically;
two ends of the X-axis slide rail are movably arranged between the two groups of Y-axis slide rails through slide blocks;
one end of the Z-axis slide rail is installed on the X-axis slide rail through a slide block, and the front end of the other end of the Z-axis slide rail is provided with a sucker assembly and a clamping assembly through a mechanical connecting piece.
As an improvement, the device also comprises a turnover motor and a rotating motor; the overturning motor is used for providing power when the sucker component overturns; and the rotating motor is used for providing power when the sucker assembly and the clamping assembly move.
As an improvement, the gripping assembly is provided with at least one set for gripping and/or placing slides, slide magazines, mold platens, and disposable funnels.
As an improvement, the device also comprises a waste recovery mechanism which is used for independently recovering the same type of consumables after tabletting is finished.
As an improvement, the consumable is a disposable funnel and a slide bin.
As an improvement, the disposable funnel of the funnel lifting mechanism is arranged to be an inlet end, a plurality of groups of structures are arranged side by side at intervals, and the distance between the outlet ends corresponds to the position of a slide in the slide bin.
Meanwhile, the sheet making method of the full-automatic sheet making machine for collecting the liquid-based cells comprises the following specific steps:
(I) shaking preparation before tabletting
Putting a plurality of groups of cell liquid boxes into a stirring mechanism, starting a stirring box body, mechanically shaking the cell liquid boxes inside, after shaking for 0.2-1h, dropping the cell liquid boxes from an outlet at the bottom of the stirring box body onto a connected transmission mechanism, conveying the cell liquid boxes to the inside of a shaking mechanism, and after shaking for 0.1-1.5h, shaking the cell liquid boxes uniformly for later use;
(II) turning over and opening the cell liquid box
Clamping the cell liquid box by the clamping and rotating mechanism, turning over the cell liquid box, then rotating to open the cover of the cell liquid box, opening the surface layer of the cover of the cell liquid box by the operation of the finger cylinder, and waiting for exporting the cell liquid in the cell liquid box with the cover opened by the clamping and turning mechanism;
(III) preparing upper piece, mould and funnel
Operating a rotary cylinder of the sucking disc and the clamping mechanism, and placing a group of slide bins to slide making station positions;
then the rotating cylinder of the sucking disc and the clamping mechanism is operated to suck a group of slides in the slide bin lifting mechanism and place the slides in the upper group of slide bins;
then the rotating cylinder of the sucking disc and the clamping mechanism is operated, the mold pressing plate is sucked and placed above the slide, and then the moving and sheet feeding mechanism is clamped on the mold pressing plate, so that the slide bin, the slide and the mold pressing plate are of an integrated structure;
then the rotating cylinder of the sucking disc and the clamping mechanism is operated, and the sucking disposable funnel is placed at the middle position of the integrated structure;
(IV) placing cell sap
Allowing the cell sap prepared in the step (II) to enter along the inlet end of the funnel of the disposable funnel and flow out along the outlets of the plurality of passages, uniformly flowing into each mould pressing plate in the step (III), and standing for a period of time to finish sampling;
(V) finishing the tabletting
Operating the rotary cylinder of the sucking disc and the clamping mechanism to take away the disposable funnel; moving the integrated structure to a waste recycling position, ejecting the clamped piece feeding mechanism, moving the die pressing plate away, and recycling and placing the die pressing plate at an initial standby position; and (4) putting the slide bin back to the original position according to the taking position, taking away the slide, completing slide production, and repeating the steps to produce the slide uninterruptedly.
As an improvement, the clamping shape on the sheet feeding mechanism is matched with the shape of the bottom plate of the die and is connected in an interference fit mode.
Has the advantages that: compared with the conventional device, the device provided by the utility model has the following advantages:
(1) the device is assembled by a plurality of mechanisms, and when a specific mechanism is abnormal, the specific mechanism can be detached and replaced independently, so that the maintenance time of the whole device is short, the assembly and disassembly are convenient, and the abnormality is conveniently checked.
(2) The device is provided with the sucking disc and gets the mechanism with pressing from both sides, has set up the multiunit collection and has absorb and press from both sides the subassembly of getting the characteristic, has overcome the thin and fragile characteristic of slide, takes out through the sucking disc and presses or put the pressure mode, can realize the sucking disc and absorb, put the process of the slide safe operation that falls.
Meanwhile, a three-dimensional movable and 360-degree turnover function integrated moving mechanism is further arranged on the sucking disc and clamping mechanism, and can be matched with the sucking disc assembly and the clamping assembly to complete movement of three-dimensional movement and 360-degree turnover, and the work of taking and placing different consumables and accessories is completed.
(3) The device still is provided with the automatic structure of mending the height together, and the concrete application is in slide storehouse lifting mechanism and funnel lifting mechanism, through using a funnel, behind a set of slide storehouse, the bottom can mend the rise height together automatically, makes things convenient for the sucking disc and presss from both sides to get the mechanism and snatchs or absorb the consumptive material, selectively sets up the counter simultaneously, can the automatic calculation, and the consumptive material is used up the back, intelligent supply, labour saving and time saving.
Drawings
FIG. 1 is a schematic view of the structure of the apparatus of the present invention.
FIG. 2 is a flow diagram of the tableting process of the apparatus of the present invention.
In the figure: the device comprises a stirring mechanism 1, a vibrating mechanism 2, a clamping and rotating mechanism 3, a finger cylinder 4, a funnel lifting mechanism 5, a clamping and overturning mechanism 6, a sucker and clamping mechanism 7, a slide bin lifting mechanism 8, a sheet conveying mechanism 9, a Y-axis slide rail 71, an X-axis slide rail 72, a Z-axis slide rail 73, a sucker component 74, a clamping and taking component 75, a stirring box body 11 and a transmission mechanism 12.
Detailed Description
The following examples are given to further illustrate the embodiments of the present invention. The following examples are intended to illustrate the utility model but are not intended to limit the scope of the utility model.
The full-automatic pelleter for collecting the liquid-based cells comprises a frame main body, wherein the frame main body internally comprises a stirring mechanism 1, a vibrating mechanism 2, a clamping and rotating mechanism 3, a funnel lifting mechanism 5, a clamping and overturning mechanism 6, an operation sucker and clamping mechanism 7, a slide cabin lifting mechanism 8 and a slide conveying mechanism 9; wherein the frame main part can be metal material or alloy material, can be according to using the place to adjust the mounted position by oneself, and is simple and convenient swift.
The stirring mechanism 1 is used for mechanically shaking the cell liquid box and primarily shaking up the cell liquid box;
the oscillating mechanism 2 is fixedly arranged on one side of the stirring mechanism 1, and secondary oscillating treatment is carried out on the cell liquid box after primary shaking-up treatment;
the clamping and rotating mechanism 3 is arranged on one side of the oscillating mechanism 2 and is used for clamping the cell liquid box after secondary oscillation treatment and rotationally opening the cover;
the funnel lifting mechanism 5 is used for lifting the disposable funnel and automatically supplementing the height of the disposable funnel after the disposable funnel is taken away;
the clamping and overturning mechanism 6 is arranged on one side of the clamping and overturning mechanism 3 and is used for clamping and overturning the cell liquid box of the rotary cover and pouring cell liquid into a station;
one end of the sucking disc and clamping mechanism 7 is fixedly arranged on the frame main body, and the other end is provided with a moving mechanism and a sucking disc in three-dimensional directions for sucking and moving the slide, the slide bin, the mold pressing plate and the disposable funnel;
the glass bin lifting mechanism 8 is arranged on one side of the sucking disc and clamping mechanism 7 and is used for lifting a group of glass bins at a time and automatically supplementing and taking the height of the glass bins away;
and the sheet feeding mechanism 9 is arranged on one side of the sucking disc and clamping mechanism 7 and is used for fixedly clamping the slide and the die pressing plate.
As an improvement, the device also comprises a slide storage bin and a mould pressing plate bin;
the slide storage bin is used for storing slides, and when the sucking disc and the clamping mechanism 7 suck the slides, the height of the slide storage bin can be automatically supplemented to the height before the slides are not sucked;
the mould pressing plate bin is used for storing the mould pressing plates and used mould pressing plates.
As an improvement, the suction cup and clamping mechanism 7 comprises a Y-axis slide rail 71, an X-axis slide rail 72, a Z-axis slide rail 73, a suction cup assembly 74 and a clamping assembly 75;
two groups of Y-axis slide rails 71 are arranged and are symmetrically and fixedly arranged on the two side frames of the frame main body at intervals;
two ends of the X-axis slide rail 72 are movably arranged between the two groups of Y-axis slide rails 71 through slide blocks;
one end of the Z-axis slide rail 73 is installed on the X-axis slide rail 72 through a slide block, and the front end of the other end of the Z-axis slide rail 73 is provided with a sucker assembly 74 and a clamping assembly 75 through mechanical connectors.
As a specific embodiment of the utility model, the utility model also comprises a turnover motor and a rotating motor; the overturning motor is used for providing power when the sucker assembly 74 overturns; the rotating motor is used for providing power when the sucker assembly 74 and the clamping assembly 75 move.
As a specific embodiment of the present invention, the gripper assembly 75 is provided in at least one set for grasping and/or placing slides, slide magazines, mold platens, and disposable funnels.
As a specific embodiment of the utility model, the device also comprises a waste recovery mechanism which is used for independently recovering the same type of consumables after tabletting is finished.
As a specific embodiment of the present invention, the consumable is a disposable funnel, slide magazine.
As a specific embodiment of the utility model, the disposable funnel of the funnel lifting mechanism 5 is arranged in a structure with one inlet end and a plurality of groups of outlet ends which are spaced side by side, and the spacing of the outlet ends corresponds to the position of the slide in the slide bin.
Meanwhile, the sheet making method of the full-automatic sheet making machine for collecting the liquid-based cells comprises the following specific steps:
(I) shaking preparation before tabletting
Putting a plurality of groups of cell liquid boxes into the stirring mechanism 1, starting the stirring box body 11, mechanically shaking the cell liquid boxes inside, after shaking for 0.2-1h, dropping the cell liquid boxes from an outlet at the bottom of the stirring box body onto a connected transmission mechanism 12, transmitting the cell liquid boxes to the inside of the oscillating mechanism (2), and after oscillating for 0.1-1.5h, shaking the cell liquid boxes uniformly for later use;
(II) turning over and opening the cell liquid box
The cell liquid box is clamped by the clamping and rotating mechanism 3, the cell liquid box is turned over and then the cover of the cell liquid box is opened in a rotating mode, the mechanical arm is driven to work by the finger cylinder 4, the surface layer of the cover of the cell liquid box is opened, and then cell liquid in the cell liquid box with the cover opened is waited to be led out for later use by the clamping and rotating mechanism 6;
(III) preparing upper piece, mould and funnel
Operating a rotary cylinder of the sucking disc and clamping mechanism 7, and placing a group of slide bins to slide making station positions;
then, the rotating cylinder of the sucking disc and clamping mechanism 7 is operated to suck a group of slides in the slide bin lifting mechanism 8 and place the slides in the upper group of slide bins;
then the rotating cylinder of the sucking disc and clamping mechanism 7 is operated, the mould pressing plate is sucked and placed above the slide, and then the moving and sheet feeding mechanism 9 is clamped on the mould pressing plate, so that the slide bin, the slide and the mould pressing plate are of an integrated structure;
then the rotating cylinder of the sucking disc and clamping mechanism 7 is operated, and the disposable funnel of the sucking funnel lifting mechanism 5 is placed at the middle position of the integrated structure;
(IV) placing cell sap
Allowing the cell sap prepared in the step (II) to enter along the inlet end of the funnel of the disposable funnel and flow out along the outlets of the plurality of passages, uniformly flowing into each mould pressing plate in the step (III), and standing for a period of time to finish sampling;
(V) finishing the tabletting
The rotating cylinder of the sucking disc and clamping mechanism 7 is operated to take away the disposable funnel; moving the integrated structure to a waste recycling position, ejecting the clamped movable sheet feeding mechanism 9, moving the die pressing plate away, and recycling and placing the die pressing plate at an initial standby position; and (4) putting the slide bin back to the original position according to the taking position, taking away the slide, completing slide production, and repeating the steps to produce the slide uninterruptedly.
In an embodiment of the present invention, the sheet feeding mechanism 9 is connected by an interference fit in a manner that an engaging shape thereof matches a shape of the mold base.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the utility model. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (8)

1. The utility model provides a gather full-automatic pelleter of liquid-based cell, includes the frame main part, its characterized in that: the frame main body internally comprises a stirring mechanism (1), a vibrating mechanism (2), a clamping and rotating mechanism (3), a funnel lifting mechanism (5), a clamping and overturning mechanism (6), a sucker and clamping mechanism (7), a slide bin lifting mechanism (8) and a slide conveying mechanism (9);
the stirring mechanism (1) is used for mechanically shaking the cell liquid box and primarily shaking up the cell liquid box;
the oscillating mechanism (2) is fixedly arranged on one side of the stirring mechanism (1), and secondary oscillating treatment is carried out on the cell liquid box after primary shaking-up treatment;
the clamping and rotating mechanism (3) is arranged on one side of the oscillating mechanism (2) and is used for clamping the cell liquid box after secondary oscillation treatment and rotatably opening the cover;
the funnel lifting mechanism (5) is used for lifting the disposable funnel and automatically supplementing the height of the funnel after the funnel is taken away;
the clamping and overturning mechanism (6) is arranged on one side of the clamping and overturning mechanism (3) and is used for clamping and overturning the cell liquid box of the rotary cover and pouring the cell liquid into a station;
one end of the sucking disc and clamping mechanism (7) is fixedly arranged on the frame main body, and the other end of the sucking disc and clamping mechanism is provided with a three-dimensional moving mechanism and a sucking disc which are used for sucking and moving a slide, a slide bin, a mold pressing plate and a disposable funnel;
the glass bin lifting mechanism (8) is arranged on one side of the sucking disc and clamping mechanism (7) and is used for lifting a group of glass bins at a time and automatically supplementing the height of the glass bins after the glass bins are taken away;
the piece feeding mechanism (9) is arranged on one side of the sucking disc and clamping mechanism (7) and is used for fixedly clamping the glass slide and the die pressing plate;
also comprises a slide storage bin and a mould pressing plate bin.
2. The full-automatic pelleter for collecting liquid-based cells of claim 1, wherein: the slide storage bin is used for storing slides, and when the sucking disc and the clamping mechanism (7) suck the slides, the height of the slide storage bin can be automatically supplemented to the height before the slides are not sucked;
the mould pressing plate bin is used for storing the mould pressing plates and used mould pressing plates.
3. The full-automatic pelleter for collecting liquid-based cells of claim 1, wherein: the sucking disc and clamping mechanism (7) comprises a Y-axis slide rail (71), an X-axis slide rail (72), a Z-axis slide rail (73), a sucking disc assembly (74) and a clamping assembly (75);
two groups of Y-axis slide rails (71) are arranged and are symmetrically and fixedly arranged on the two side frames of the frame main body at intervals;
two ends of the X-axis slide rail (72) are movably arranged between the two groups of Y-axis slide rails (71) through slide blocks;
one end of the Z-axis sliding rail (73) is installed on the X-axis sliding rail (72) through a sliding block, and the front end of the other end of the Z-axis sliding rail (73) is provided with a sucker component (74) and a clamping component (75) through a mechanical connecting piece.
4. A fully automatic pelleter for collecting liquid based cells as claimed in claim 3 wherein: the device also comprises a turnover motor and a rotating motor; the overturning motor is used for providing power when the sucker assembly (74) overturns; the rotating motor is used for providing power when the sucker assembly (74) and the clamping assembly (75) move.
5. A fully automatic pelleter for collecting liquid based cells as claimed in claim 3 or 4 wherein: the gripping assembly (75) is provided in at least one group for gripping and/or placing slides, slide magazines, mold platens, and disposable funnels.
6. The full-automatic pelleter for collecting liquid-based cells of claim 1, wherein: still include the waste recycling mechanism for independently retrieve the same type consumptive material after the film-making is accomplished.
7. A fully automatic pelleter for collecting liquid based cells as claimed in claim 6 wherein: wherein the consumables are a disposable funnel and a slide bin.
8. The full-automatic pelleter for collecting liquid-based cells of claim 1, wherein: the disposable funnel of funnel lifting mechanism (5) sets up to an entry end, the structure of the export end side by side is arranged at the interval of multiunit, and the interval of export end is corresponding with slide storehouse slide position.
CN202121899506.2U 2021-08-12 2021-08-12 Gather full-automatic pelleter of liquid-based cell Active CN215833102U (en)

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CN202121899506.2U CN215833102U (en) 2021-08-12 2021-08-12 Gather full-automatic pelleter of liquid-based cell

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113702125A (en) * 2021-08-12 2021-11-26 姚香怡 Full-automatic sheet making machine and sheet making process method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113702125A (en) * 2021-08-12 2021-11-26 姚香怡 Full-automatic sheet making machine and sheet making process method
CN113702125B (en) * 2021-08-12 2024-01-26 姚香怡 Full-automatic pelleter and pelleter process method

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