CN215739279U

CN215739279U - Thrombus taking device

Info

Publication number: CN215739279U
Application number: CN202122045169.7U
Authority: CN
Inventors: 熊丹; 邢雷; 齐妍; 陈晓龙; 程宇镳; 其他发明人请求不公开姓名
Original assignee: Changzhou Kainit Medical Technology Co ltd
Current assignee: Changzhou Kainit Medical Technology Co ltd
Priority date: 2020-08-29
Filing date: 2021-08-27
Publication date: 2022-02-08
Anticipated expiration: 2031-08-27
Also published as: CN113693679A; CN216317846U; CN216021269U; CN113693678A

Abstract

The application provides a get and tie device for apoplexy, thrombus or hemangioma's treatment, it adopts double-deck support to get ties the net, double-deck support is got to tie the net and is got to tie net (11) and skin including the inlayer and is got to tie net (12), double-deck support is got to tie the net and is got to tie net and/or the sculpture formula is got to tie net and/or weave the formula and get one or two kinds in the net including the formula of expanding certainly.

Description

Thrombus taking device

Technical Field

The application belongs to the field of medical equipment, in particular to a thrombus removal device.

Background

Ischemic stroke is also called cerebral infarction, and is called stroke or stroke in traditional Chinese medicine. The disease is caused by blood supply disorder of local brain tissue areas caused by various reasons, and the ischemic and hypoxic lesion necrosis of the brain tissue is caused, so that the clinically corresponding nerve function deficiency expression is generated. Cerebral infarction is divided into main types such as cerebral thrombosis, cerebral embolism, lacunar infarction and the like according to different pathogenesis.

Cerebral thrombosis is the most common type of cerebral infarction, accounting for about 60% of all cerebral infarctions, and so the so-called "cerebral infarction" actually refers to cerebral thrombosis.

Interventional therapy includes intravascular mechanical thrombectomy and arterial thrombolysis.

(1) The mechanical thrombus removal in the blood vessel can obviously improve the prognosis of patients with cerebral arterial thrombosis caused by acute aortic occlusion. In 2018, the diagnosis and treatment guideline for acute ischemic stroke recommends a conditional medical institution, and a clinical medical team trained by the guideline carries out the diagnosis and treatment guideline for acute ischemic stroke, so that the indication of mechanical thrombus removal in blood vessels is strictly mastered.

(2) Arterial thrombolysis, which makes thrombolysis medicine directly reach local part of thrombus, theoretically, the blood vessel recanalization rate is higher than that of venous thrombolysis, and the bleeding risk is reduced. However, because of the lack of clinical evidence demonstrating the benefits of arterial thrombolysis, current first-line intravascular therapy is mechanical embolectomy.

For patients with stroke who are delivered to the hospital in a timely manner, the conventional treatment regimen is drug thrombolysis, but the optimal window time for drug thrombolysis (the time from onset of the disease to treatment) is within 4 hours, while the short thrombolysis time window results in less than 10% of patients receiving effective thrombolytic therapy; second, drug thrombolysis is essentially ineffective against larger thrombi.

In order to solve the above-mentioned problem of drug thrombolysis, a method of mechanically eliminating thromboembolism has been a hot research focus in recent years. The core of the mechanical thrombus removal is a thrombus removal device. The top end of the thrombus taking device is provided with a bracket, the push rod is connected behind the bracket, thrombus is embedded after the bracket is expanded, the thrombus is fixed, and then the push rod is withdrawn to remove the thrombus. The method can directly remove thrombus, has remarkable effect, greatly prolongs the treatment time window, reaches 24 hours at most, and strives for valuable rescue time for patients.

However, in the process of fixing and transferring the thrombus, the thrombus easily spreads and dissociates. Meanwhile, due to different soft and hard properties of thrombus, the clamping force of the thrombus taking device on the thrombus is easy to be insufficient, so that residual thrombus in blood vessels at other positions or thrombus taking failure is easily caused. Therefore, the current medical devices for enhancing the clamping force of thrombus are in need of research.

SUMMERY OF THE UTILITY MODEL

This application aims at providing a thrombectomy device, makes the thrombectomy success rate higher.

The application provides a get and tie device for apoplexy, thrombus or hemangioma's treatment, it adopts double-deck support to get ties the net, double-deck support is got to tie the net and is got to tie net and skin including the inlayer and get to tie the net, double-deck support is got to tie the net and is got to tie net and/or adjustable formula and get to tie the net and/or the formula of carving is got to tie net and/or weave one or two kinds in the net.

Preferably, the thrombus removal device comprises a support, the support is a double-layer support thrombus removal net, and the outer layer thrombus removal net is wrapped outside the inner layer thrombus removal net.

Preferably, the inner layer embolization mesh and the outer layer embolization mesh are the same type of embolization mesh or different types of embolization meshes.

Preferably, the inner layer embolectomy mesh and the outer layer embolectomy mesh are self-expanding embolectomy meshes.

Preferably, the thrombus removal device further comprises a core wire, and the proximal ends of the inner layer thrombus removal net and the outer layer thrombus removal net are connected to the core wire.

Preferably, the inner layer embolectomy mesh is an adjustable embolectomy mesh, and the outer layer embolectomy mesh is a self-expanding embolectomy mesh.

Preferably, the embolectomy device further comprises a core wire and a sleeve, wherein the sleeve is sleeved on the core wire, the proximal end of the inner layer embolectomy mesh is connected to the sleeve, the distal end of the inner layer embolectomy mesh is connected to the core wire, the proximal end of the outer layer embolectomy mesh is connected to the sleeve, and the inner layer embolectomy mesh can be controllably expanded through the movement of the core wire relative to the sleeve.

Preferably, the inner layer embolectomy net and the outer layer embolectomy net are both adjustable embolectomy nets.

Preferably, the thrombus removal device further comprises a core wire and a sleeve, the sleeve comprises an inner sleeve and an outer sleeve, the outer sleeve is sleeved on the inner sleeve, the core wire penetrates through the inner sleeve, the proximal end of the inner thrombus removal net is connected to the inner sleeve, the distal end of the inner thrombus removal net is connected to the core wire, the proximal end of the outer thrombus removal net is connected to the outer sleeve, and the distal end of the outer thrombus removal net is connected to the core wire.

Preferably, the inner-layer thrombus taking net is a self-expanding thrombus taking net, and the outer-layer thrombus taking net is an adjustable thrombus taking net.

Preferably, the thrombus removal device further comprises a core wire and a sleeve, the sleeve is sleeved on the core wire, the proximal ends of the inner layer thrombus removal net and the outer layer thrombus removal net are both connected to the sleeve, and the distal end of the outer layer thrombus removal net is connected to the core wire.

Preferably, the wall of the sleeve is cut to form a helix, the helix of the sleeve having locations with different pitches.

By adopting the technical scheme, the double-layer bracket embolectomy net can be 'double-nested'; the combination strength of the support and the thrombus is enhanced, the support and the thrombus are combined stably, the thrombus is limited to be free, the falling of fragments in the thrombus taking process is prevented, and the diffusion of residual microthrombus in the thrombus removing process to blood vessels at other positions is avoided. The thrombus is taken out favorably, the cell ischemia injury caused by long-time operation is avoided, the success rate of thrombus taking operation is improved, and the practicability is high.

Drawings

Fig. 1 shows a schematic structural diagram of a embolectomy device according to a first embodiment of the present application.

Fig. 2 shows a partial enlarged view of fig. 1.

Fig. 3 shows a schematic structural diagram of a embolectomy device according to a second embodiment of the present application.

Fig. 4 shows a schematic structural view of a stent, core wire and sleeve of a thrombectomy device according to a second embodiment of the present application.

Fig. 5 shows a schematic structural view of a holder of a thrombectomy device according to a second embodiment of the present application.

Fig. 6 shows a schematic structural view of another stent of a thrombectomy device according to the second embodiment of the present application.

Fig. 7 shows a schematic structural view of another possible embolectomy device according to the second embodiment of the present application.

Fig. 8 shows a schematic structural view of a stent, core wire and sleeve of a thrombectomy device according to a third embodiment of the present application.

Fig. 9 shows a schematic structural view of a holder of a embolectomy device according to a third embodiment of the present application.

Fig. 10 shows a schematic structural view of another stent of a thrombectomy device according to a third embodiment of the present application.

Fig. 11 shows a schematic structural view of a stent, core wire and sleeve of a thrombectomy device according to a fourth embodiment of the present application.

Fig. 12 shows a schematic structural view of a holder of a embolectomy device according to a fourth embodiment of the present application.

Description of the reference numerals

1 protective part of inner layer embolectomy net 12 and outer layer embolectomy net 13 of bracket 11

2-core filament

3 casing 31 inner layer casing 32 outer layer casing

4 handle

5 buttons.

Detailed Description

In order to more clearly illustrate the above objects, features and advantages of the present application, a detailed description of the present application is provided in this section in conjunction with the accompanying drawings. This application is capable of embodiments in addition to those described herein, and is intended to cover such departures from the present disclosure as come within known or customary practice in the art to which this application pertains and which fall within the limits of the appended claims. The protection scope of the present application shall be subject to the claims.

(first embodiment)

As shown in fig. 1 and 2, the embolectomy device comprises a stent 1 and a core wire 2.

In the following description, the end of the stent 1 close to the operator is referred to as the proximal end (right end in fig. 1) of the stent 1, and the end of the stent 1 far from the operator is referred to as the distal end (left end in fig. 1) of the stent 1.

The support 1 is double-deck support and gets and tie the net, and support 1 includes that the net 11 is got to the inlayer and ties the net 12 is got to the skin, and under the state that does not receive external force constraint, the radial dimension that the net 12 is got to the skin and is greater than the radial dimension that the net 11 is got to the inlayer on the whole, and the net 12 is got to the skin package is got to the inlayer and is tied the outside of net 11. It will be appreciated that the inner layer 11 and outer layer 12 may also have overlapping, touching portions. The inner layer embolectomy mesh 11 and the outer layer embolectomy mesh 12 are the same type of embolectomy mesh, and the inner layer embolectomy mesh 11 and the outer layer embolectomy mesh 12 can both be self-expansion type embolectomy meshes. The self-expansion bolt-taking net can be carved and is also called as a carving bolt-taking net.

The stent 1 may be made of nitinol, and the mesh structure may be dense in different portions of the inner layer 11 and/or the outer layer 12.

The proximal ends of the inner layer embolization mesh 11 and the outer layer embolization mesh 12 are attached to the core wire 2. Before use, the inner layer embolectomy mesh 11 and the outer layer embolectomy mesh 12 are both in a contracted state under the constraint of a guide catheter. In use, the stent 1 is expanded to cover and/or embed thrombus by means of the shape memory property of the nickel-titanium alloy after the constraint of the guide catheter is removed.

It can be understood that the inner and outer layers of the embolectomy mesh can be 'double nested'; the combination strength of reinforcing support 1 and thrombus, support 1 and thrombus combine stably, and the restriction thrombus is free, prevents that the piece of thrombectomy in-process from droing, avoids removing remaining little thrombus diffusion to other positions blood vessel departments in the thrombus in-process. The thrombus is taken out favorably, the cell ischemia injury caused by long-time operation is avoided, the success rate of thrombus taking operation is improved, and the practicability is high.

In other possible embodiments, the stent 1 may not only include the inner layer embolization mesh 11 and the outer layer embolization mesh 12, but may also have a structure with more layers of embolization meshes, for example, the stent 1 may have three layers of embolization meshes.

(second embodiment)

The same or similar parts in the second embodiment as those in the first embodiment are denoted by the same reference numerals.

As shown in fig. 3 to 6, the present application proposes a thrombus removal device which comprises a bracket 1, a core wire 2, a sleeve 3, a handle 4 and a button 5.

The support 1 comprises an inner layer embolism taking net 11 and an outer layer embolism taking net 12, the inner layer embolism taking net 11 and the outer layer embolism taking net 12 can be different types of embolism taking nets, the inner layer embolism taking net 11 can be an adjustable embolism taking net, the inner layer embolism taking net 11 can be woven, the outer layer embolism taking net 12 can be a self-woven embolism taking net, the outer layer embolism taking net 12 can be carved, and the outer layer embolism taking net is also named as a carved embolism taking net. The inner layer embolectomy mesh 11 and the outer layer embolectomy mesh 12 can be made of nickel titanium alloy, and the nickel titanium alloy has elasticity. The degree of densification of the network may vary in different parts of the stent 1.

The sleeve 3 is sleeved on the core wire 2, the core wire 2 can move in the sleeve 3 along the front-back direction, the near end of the inner layer embolectomy net 11 is connected to the sleeve 3, the far end of the inner layer embolectomy net 11 is connected to the core wire 2, and the core wire 2 can slide relative to the sleeve 3 along the front-back direction. The inner layer embolectomy mesh 11 can be expanded to a shape with thin ends and thick middle by pulling the core wire 2 towards the proximal end by operating the button 5, so that the inner layer embolectomy mesh 11 is embedded into the thrombus.

The proximal end of the outer layer embolectomy mesh 12 is connected to the sleeve 3, and after the outer layer embolectomy mesh 12 is removed from the constraint of the guide catheter, the distal end of the outer layer embolectomy mesh 12 can be expanded by means of the memory property of the distal end so as to be embedded into thrombus.

Optionally, the distal end of the inner layer embolectomy mesh 11 is formed with a protection part 13 (also called a tip), the protection part 13 can be bent relative to the sleeve 3, the protection part 13 can be made of soft material, and the protection part 13 is beneficial to steering the stent 1 in the blood vessel to prevent the stent 1 from damaging the blood vessel. It will be appreciated that the protection 13 may also be straight when not subjected to external forces and does not have to be bent with respect to the sleeve 3.

One end of the core wire 2 is connected to the distal end of the inner layer embolization mesh 11, and the other end of the core wire 2 is connected to the button 5. One end of the cannula 3 is connected to the proximal ends of the inner layer embolectomy mesh 11 and the outer layer embolectomy mesh 12, and the other end of the cannula 3 is connected to the handle 4.

The handle 4 and/or the button 5 are provided with locking structures that lock the button 5 relative to the handle 4 so that the shape of the stand 1 can be maintained.

Preferably, the handle 4 may be provided with graduation marks located beside the button 5 for marking the displacement of the button 5 in relation to the diameter of the holder 1. The button 5 is provided with a pointer, and the pointer points to the scale marks, so that the position of the button 5 can accurately correspond to the scale marks.

Further, the sleeve 3 may be woven using a metal wire, may be made of a metal tube, or may be formed by combining a metal wire and a metal tube. The metal tube may be cut (e.g. laser cut) in the axial direction of the tube to form a spiral structure in the wall of the tube, which spiral structure may adjust the hardness of the metal tube, resulting in a better fracture resistance of the sleeve 3. The pitch of the helical structure may be different at different parts of the cannula 3, so that corresponding sections of the cannula 3 have a suitable stiffness, e.g. the proximal pitch of the cannula 3 is smaller and the distal pitch of the cannula 3 is larger.

Generally, the hardness of the distal part of the cannula 3 is less than that of the proximal part of the cannula 3, the distal part of the cannula 3 is softer and easier to move in the blood vessel, and the proximal part of the cannula 3 is harder and easier to transmit the pushing force. The distal end of the sleeve 3 (the portion near the stent 1) uses a softer structure (e.g., a wire braid, a metal tube with a helical structure, or a combination of both); a stiffer structure (e.g., a metal tube without a helical structure) is used for the proximal end of the cannula 3 (the portion near the handle 4).

The inner layer embolectomy mesh 11 can be deformed by applying a force in the front-rear direction, and when the two end portions of the inner layer embolectomy mesh 11 approach under the action of an external force, the inner layer embolectomy mesh 11 can be expanded to enlarge the diameter of the inner layer embolectomy mesh 11, and the expanded inner layer embolectomy mesh 11 can be in a spindle shape with a thick middle and thin two ends. The inner layer embolectomy net 11 can have elasticity, and the expanded inner layer embolectomy net 11 can have the tendency of recovering the original state under the effect of the elasticity.

Before use, the inner layer embolectomy mesh 11 and the outer layer embolectomy mesh 12 are in a contracted state. When in use, the outer layer thrombus taking net 12 is embedded into thrombus by means of the expansion of shape memory property of the nickel-titanium alloy after the constraint is removed, and the inner layer thrombus taking net 11 is adjustably expanded and embedded into the thrombus through the core wire 2.

In other possible embodiments, as shown in fig. 7, the sleeve 3 may be attached to a button 5, the core wire 2 may be attached to a handle 4, and pushing the button 5 distally may expand the stent 1 to embed the thrombus.

During operation, the stent 1 firstly passes through the thrombus, then the button 5 is pushed forwards to move the sleeve 3 forwards, and the stent 1 expands to fix the thrombus on the stent 1. Then, the handle 4 is held to retract the whole of the push-controlled thrombus removal device, so that the thrombus can be recovered through the guide catheter. Before the stent 1 and the thrombus enter the guide catheter, the stent 1 is contracted to a certain degree, so that the stent 1 and the thrombus can enter the guide catheter conveniently. The handle 4 is kept still, namely the whole position of the push-controlled bolt taking device is not moved, the button 5 is pulled backwards, and the sleeve 3 is pulled backwards to be easily controlled. When the stent 1 is contracted, the distal end position of the stent 1 is not changed, the proximal end guide catheter of the stent 1 moves, the thrombus is stably fixed with the stent 1, the thrombus is not easy to fall off, and even if the thrombus falls off, the thrombus can be easily collected into the guide catheter along with the proximal end movement of the stent 1.

(third embodiment)

The same or similar parts in the third embodiment as those in the second embodiment are denoted by the same reference numerals.

As shown in fig. 8 to 10, the stent 1 comprises an inner layer embolectomy mesh 11 and an outer layer embolectomy mesh 12, the inner layer embolectomy mesh 11 and the outer layer embolectomy mesh 12 can be the same type of embolectomy mesh, and both the inner layer embolectomy mesh 11 and the outer layer embolectomy mesh 12 can be woven adjustable embolectomy meshes.

The sleeve 3 comprises an inner sleeve 31 and an outer sleeve 32, the outer sleeve 32 is sleeved on the inner sleeve 31, and the core wire 2 passes through the inner sleeve 31. The proximal end of the inner screen 11 is attached to the inner sleeve 31 and the distal end of the inner screen 11 is attached to the core wire 2. The proximal end of the outer embolization mesh 12 is attached to the outer sleeve 32, and the distal end of the outer embolization mesh 12 is attached to the core wire 2.

Optionally, the distal end of the outer layer embolectomy mesh 12 is formed with a protection part 13 (also called a tip), the protection part 13 is bent relative to the sleeve 3, the protection part 13 can be made of soft material, and the protection part 13 is beneficial to turning the stent 1 in the blood vessel to prevent the stent 1 from damaging the blood vessel.

In other possible embodiments, the sleeve may be a single layer, and the inner layer embolization mesh 11 and the outer layer embolization mesh 12 may be attached to the same sleeve.

(fourth embodiment)

The same or similar parts in the fourth embodiment as those in the second embodiment are denoted by the same reference numerals.

As shown in fig. 11 and 12, the stent 1 includes an inner layer embolectomy mesh 11 and an outer layer embolectomy mesh 12, the inner layer embolectomy mesh 11 and the outer layer embolectomy mesh 12 may be different kinds of embolectomy meshes, the inner layer embolectomy mesh 11 may be a self-expansion type embolectomy mesh, and the outer layer embolectomy mesh 12 may be an adjustable type embolectomy mesh.

The proximal ends of the inner layer embolectomy mesh 11 and the outer layer embolectomy mesh 12 are both connected to the sleeve 3, and the distal end of the outer layer embolectomy mesh 12 is connected to the core wire 2.

It will be appreciated that the inner screen 11 cannot be controlled for expansion and that if it is oversized it may interfere with the outer screen 12 and therefore the inner screen 11 is not oversized. The inner layer embolectomy mesh 11 is limited by the outer layer embolectomy mesh 12, and the inner layer embolectomy mesh 11 can expand sufficiently after the outer layer embolectomy mesh 12 expands controllably.

While the present application has been described in detail with reference to the above embodiments, it will be apparent to those skilled in the art that the present application is not limited to the embodiments described in the present specification. The present application can be modified and implemented as a modified embodiment without departing from the spirit and scope of the present application defined by the claims. Therefore, the description in this specification is for illustrative purposes and does not have any limiting meaning for the present application.

Claims

1. The utility model provides a thrombectomy device for apoplexy, thrombus or hemangioma's treatment, its characterized in that, it adopts double-deck support thrombectomy net, double-deck support thrombectomy net is including the inlayer and thrombectomy net and the skin thrombectomy net, double-deck support thrombectomy net is including one or two kinds in the formula of can expanding thrombectomy net and/or the adjustable thrombectomy net and/or the sculpture formula thrombectomy net and/or the formula of weaving thrombectomy net.

2. The embolectomy device of claim 1, wherein the embolectomy device comprises a stent, the stent is a double-layer stent embolectomy mesh, and the outer layer embolectomy mesh is wrapped outside the inner layer embolectomy mesh.

3. The embolectomy device of claim 2, wherein the inner layer embolectomy mesh and the outer layer embolectomy mesh are the same type of embolectomy mesh or different types of embolectomy meshes.

4. The embolectomy device of claim 2, wherein the inner layer embolectomy mesh and the outer layer embolectomy mesh are both self-expanding embolectomy meshes.

5. The embolectomy device of claim 4, further comprising a core wire, wherein the proximal ends of the inner and outer layers of the embolectomy mesh are attached to the core wire.

6. The embolectomy device of claim 2, wherein the inner layer embolectomy mesh is an adjustable embolectomy mesh, and the outer layer embolectomy mesh is a self-expanding embolectomy mesh.

7. The embolectomy device of claim 6, further comprising a core wire and a sleeve, wherein the sleeve is sleeved on the core wire, the proximal end of the inner layer embolectomy mesh is connected to the sleeve, the distal end of the inner layer embolectomy mesh is connected to the core wire, the proximal end of the outer layer embolectomy mesh is connected to the sleeve, and the inner layer embolectomy mesh can be controllably expanded by moving the core wire relative to the sleeve.

8. The embolectomy device of claim 2, wherein the inner layer embolectomy mesh and the outer layer embolectomy mesh are adjustable embolectomy meshes.

9. The embolectomy device of claim 8, further comprising a core wire and a sleeve, wherein the sleeve comprises an inner sleeve and an outer sleeve, the outer sleeve is sleeved on the inner sleeve, the core wire passes through the inner sleeve, the proximal end of the inner embolectomy mesh is connected to the inner sleeve, the distal end of the inner embolectomy mesh is connected to the core wire, the proximal end of the outer embolectomy mesh is connected to the outer sleeve, and the distal end of the outer embolectomy mesh is connected to the core wire.

10. The embolectomy device of claim 2, wherein the inner layer embolectomy mesh is a self-expanding embolectomy mesh, and the outer layer embolectomy mesh is an adjustable embolectomy mesh.

11. The embolectomy device of claim 10, further comprising a core wire and a sleeve, wherein the sleeve is sleeved on the core wire, the proximal ends of the inner layer embolectomy mesh and the outer layer embolectomy mesh are both connected to the sleeve, and the distal end of the outer layer embolectomy mesh is connected to the core wire.

12. The embolectomy device of any of claims 7, 9, and 11, wherein the wall of the cannula is cut to form a helix, and the helix of the cannula has sites with different pitches.