CN109223107A - One kind taking pin device - Google Patents
One kind taking pin device Download PDFInfo
- Publication number
- CN109223107A CN109223107A CN201811331717.9A CN201811331717A CN109223107A CN 109223107 A CN109223107 A CN 109223107A CN 201811331717 A CN201811331717 A CN 201811331717A CN 109223107 A CN109223107 A CN 109223107A
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- Prior art keywords
- network
- bracket
- pin device
- outer tube
- mandrel
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- 238000007493 shaping process Methods 0.000 claims description 19
- 238000004513 sizing Methods 0.000 claims description 16
- 239000000463 material Substances 0.000 claims description 15
- 238000009954 braiding Methods 0.000 claims description 12
- 238000001816 cooling Methods 0.000 claims description 7
- 238000009826 distribution Methods 0.000 claims description 7
- 239000007769 metal material Substances 0.000 claims description 4
- 208000007536 Thrombosis Diseases 0.000 abstract description 22
- 210000004204 blood vessel Anatomy 0.000 abstract description 17
- 238000013461 design Methods 0.000 abstract description 11
- 230000002792 vascular Effects 0.000 abstract description 11
- 230000003902 lesion Effects 0.000 abstract description 10
- 208000005189 Embolism Diseases 0.000 description 9
- 208000006011 Stroke Diseases 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 8
- 230000002537 thrombolytic effect Effects 0.000 description 8
- 239000000956 alloy Substances 0.000 description 6
- 229910001000 nickel titanium Inorganic materials 0.000 description 6
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 6
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 6
- 230000001154 acute effect Effects 0.000 description 5
- 208000001435 Thromboembolism Diseases 0.000 description 4
- 229910045601 alloy Inorganic materials 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 238000007917 intracranial administration Methods 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 206010008190 Cerebrovascular accident Diseases 0.000 description 3
- 201000001429 Intracranial Thrombosis Diseases 0.000 description 3
- 230000002490 cerebral effect Effects 0.000 description 3
- 230000000302 ischemic effect Effects 0.000 description 3
- 229910052697 platinum Inorganic materials 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 206010008132 Cerebral thrombosis Diseases 0.000 description 2
- 241000676840 Elater Species 0.000 description 2
- 239000004677 Nylon Substances 0.000 description 2
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
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- 239000012634 fragment Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 229920001778 nylon Polymers 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 229960000103 thrombolytic agent Drugs 0.000 description 2
- 238000009941 weaving Methods 0.000 description 2
- 208000014644 Brain disease Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 241000549343 Myadestes Species 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 206010053648 Vascular occlusion Diseases 0.000 description 1
- 238000002583 angiography Methods 0.000 description 1
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- 210000001367 artery Anatomy 0.000 description 1
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- 229910052802 copper Inorganic materials 0.000 description 1
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- 238000005520 cutting process Methods 0.000 description 1
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- 230000003073 embolic effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000016507 interphase Effects 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000003447 ipsilateral effect Effects 0.000 description 1
- 238000009940 knitting Methods 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
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- 230000007115 recruitment Effects 0.000 description 1
- 230000000250 revascularization Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 229910001285 shape-memory alloy Inorganic materials 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 229910052715 tantalum Inorganic materials 0.000 description 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000013151 thrombectomy Methods 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
- A61B2017/2215—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having an open distal end
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Prostheses (AREA)
Abstract
The present invention provides one kind to take pin device, comprising: takes bolt bracket, transportation system and push handle.Compared with prior art, the present invention be adjusted network can according to the diameter of diseased region blood vessel, improve the matching for taking bolt bracket and lesion vessels by movement of the mandrel in outer tube；Meanwhile the grid gap of network by proximal end to being distally gradually reduced, the mesh design that density matches guarantees that bracket can quickly be embedded in combination and fishing capacity endovascular while that increase bracket and thrombus；Furthermore the density for increasing distal stent grid, can effectively prevent broken small Thromboembolus to fall off from bracket and reduce bracket when passing through blood vessel to the damage of vascular wall；The distal end of last bracket is provided with spring, increases the flexibility for taking bolt bracket；Finally by the cooperation of push handle casing and pushing hands, the operability for taking bolt bracket is improved.
Description
Technical field
The invention belongs to the field of medical instrument technology more particularly to one kind to take pin device.
Background technique
Treatment for ischemic cerebral stroke patients, removing thrombus speed speed is a key index.If rescue is not
In time, treatment is slow, it is more likely that effect after influencing more.But traditional chemicals thrombolytic effect is slow, is unable to satisfy
To the rate request of patients with acute ischemic cerebral stroke treatment, namely why many Patients with Stroke are non-extremely i.e. residual for this.
At present there are mainly two types of the treatment methods of Intracranial thrombus: drug thrombolysis and machinery take bolt.
Drug thromboembolism treatment be thrombolytics inject lesion where endovascular lesion near, lesion part instantaneously
Very high thrombolytics concentration is formed, accelerates thrombolysis speed, and then increase the chance of revascularization, and passes through unique skill of developing
Art is in real time to surgical procedure full name implementing monitoring.According to result of study surface is faced, intravenous thrombolysis should carry out in morbidity 3 hours,
Arterial thrombolysis time window is within 6 hours.Since drug thrombolytic treatment time window is shorter, and thromboembolism treatment is only applicable to volume
Lesser thrombus, it is unsatisfactory to the therapeutic effect of large volume thromboembolism, so it is final only about 3%~5% patient
It is suitble to do drug thromboembolism treatment.
It is exactly to use that bolt bracket is taken to take out the embolus of occluding vascular in vitro that so-called machinery, which takes bolt,.The country also rarely has the country at present
Company listing product, machinery take in bolt instrument market also mainly based on the product of the offshore companies such as Medtronic, Johnson & Johnson.According to
Investigation, there is 3,000,000 newly-increased cerebral thrombosis group in China every year at present, and acute cerebral thrombosis accounts for the ratio of cerebral apoplexy also by 55.8%
81.6% is risen to, the big disease of brain first is become.Leading to again for blood vessel is the key that treatment acute ischemic cerebral apoplexy, and machinery takes
Bolt includes following several method: capture takes bolt, suction that bolt, rotary-cut is taken to take bolt etc..Capture takes bolt, and when taking massive, effect is most
It is good, but the patch be easy to causeing on vascular wall and broken thrombi, which flow to distal vessels after falling off, causes new embolism, one
Denier blocks important branch vessel, it will cause serious malpractice, and often exist when taking bolt and bolt is taken to be not thorough,
There is the problem of residual, it is easy to lead to the formation of secondary acute thrombus.Suction takes bolt effect when taking fritter embolus preferable, is taking
It is blocked in order to prevent when massive, suction tube needs to aspirate again after smashing thrombus to pieces repeatedly, cumbersome and is easy to damage
Blood vessel.It is larger that rotary-cut takes bolt to damage caused by vascular wall, it is easy to cause complication.
Current takes patch of pin device during taking bolt on vascular wall and broken thrombi to be easy to fall off, and flows to
Distal vessels cause new embolism.It is reported that there are about 70% blood vessel intervention take bolt perform the operation in observed thrombus fragment and
Fragment flows to distal vessels, and which increase the risks of patient vessel's embolism again.
The Chinese patent of Publication No. CN105476689A discloses one kind and takes bolt holder device, including takes bolt bracket, defeated
Seal wire, guiding seal wire and Marking ring are sent, it is in the reticular structure of sealing two ends that proximal end, which takes bolt bracket, distal embolic protection bracket,；Publication number
Disclose one kind for the Chinese patent of CN104000635A and take bolt device and its take pin device, this take pin device include guiding wire,
Push rod, outer sheath and the inner tube mobile relative to outer sheath；The United States Patent (USP) of Patent No. US9,510,855B also discloses
It is a kind of can be used for blood vessel take pin device comprising skeleton, skeleton can be woven by shape-memory alloy wire, to capture blood
Bolt.But these take pin device that must could pass through lesion under the cooperation of microtubular, and discharge after-poppet in target vascular site
The diameter of opening can not be adjusted, and especially when passing through local stenosis lesion, the thrombus of capture is easy to take off due to being not fixed firmly
It falls.
The Chinese patent of Publication No. CN204337002U discloses a kind of controllable intracranial vessel thrombectomy device, there is adjusting
Seal wire takes bolt device, outer fixed sheath, and bolt device one end is taken to be fixedly connected with outer fixed sheath by fixator, and the other end and head end develop
Connect by the way that fixator is fixed.But it is single establishment that this, which takes bolt bracket, and the larger easy scratch blood vessel of radial force, distal end gap is larger,
Small thrombus is easy to fall off, and the developing material of stent surface coated is easy to fall off, conical support Design and blood contacting surface
Product is limited.
Currently on the market most by American-European doctor receive encephalic acute thrombus extraction system be EV3 Company of the U.S.
Solitaire FR system, which captures the mode for taking bolt using cylinder stent, by microtubular by instrument in lesion
Thrombus is entangled after the release of position, is withdrawn from after then taking in instrument and thrombus in the bigger guiding catheter of internal diameter together external.But
It is to reflect according to clinic, when taking bolt using the instrument, since distal stent be that opening designs weaker, thrombus of arresting power to thrombus
It is fallen off on bolt device easily in removal process from taking, needs to capture repeatedly, when not only having increased the pain of patient, but also having extended operation
Between, also add distal vessels blocking risk therefore,
Summary of the invention
In view of this, this takes pin device flexibility the technical problem to be solved in the present invention is that providing one kind takes pin device
Good, diameter is adjustable and catches grip with stronger.
The present invention provides one kind to take pin device, comprising:
Take bolt bracket, transportation system and push handle；
Described to take bolt bracket include network and spring, and the grid gap of described network one end is less than the other end
Grid gap；The network gap is provided with spring at the top of small one end；
The transportation system includes mandrel and the outer tube for mandrel traveling；
The mandrel runs through entire outer tube and network；
The top fixation of the big one end in network grid gap is collected in one end of outer tube；
The push handle includes shell and pushing hands；
Slideway is provided on the shell；The pushing hands is set in slideway, and can be slided along slideway；
The shell is connected with the other end of outer tube, and the pushing hands is connected with the other end of mandrel；
Or the shell is connected with the other end of mandrel, the pushing hands is connected with the other end of outer tube.
It preferably, further include the first developing ring and the second developing ring；First developing ring is set to network and outer
Between pipe；Second developing ring is set between network and spring.
Preferably, the small parts transversely spacing in network grid gap is 1~5mm；The network grid
The big parts transversely spacing in gap is 1.2~3 times of the small parts transversely spacing in network gap.
Preferably, one end that the spring is not contacted with network is closed using smooth material, and the smooth material
Top be arc-shaped.
Preferably, the network is the staggered supporting structure of forward-reverse spiral as made of the braiding of superlastic silk.
Preferably, the superlastic silk includes visible metal material under X-ray.
Preferably, the network is prepared according to the following steps:
Using cylindric or columned bracket sizing tooling；The surface of the bracket sizing tooling is provided with spiral
The a plurality of anchor point of distribution；
One end of superlastic silk is fixed on to one end of bracket sizing tooling, is then advanced along anchor point, braiding obtains net
Shape supporting structure；The grid gap of network structure one end is less than the grid gap of the other end；
The network structure heat-shaping is obtained into network after cooling.
Preferably, the network is prepared according to the following steps:
It is cut on tubing by laser and obtains network structure；
The grid gap of network structure one end is less than the grid gap of the other end；
The network structure heat-shaping is obtained into network after cooling.
Preferably, the temperature of the heat-shaping is 400 DEG C~510 DEG C；The time of the heat-shaping is 1~15min.
Preferably, slideway is provided with scale on the shell.
The present invention provides one kind to take pin device, comprising: takes bolt bracket, transportation system and push handle；It is described to take bolt branch
Frame includes network and spring, and the grid gap of described network one end is less than the grid gap of the other end；The net
Shape standoff gap is provided with spring at the top of small one end；The transportation system includes mandrel and the outer tube for mandrel traveling；Institute
Mandrel is stated through entire outer tube and network；The top fixation of the big one end in network grid gap is collected in outer tube
One end；The push handle includes shell and pushing hands；Slideway is provided on the shell；The pushing hands is set in slideway,
And it can be slided along slideway；The shell is connected with the other end of outer tube, and the pushing hands is connected with the other end of mandrel；Or
The shell is connected with the other end of mandrel, and the pushing hands is connected with the other end of outer tube.Compared with prior art, this hair
The bright movement by mandrel in outer tube be adjusted network can according to the diameter of diseased region blood vessel, improve and take
The matching of bolt bracket and lesion vessels；Meanwhile the grid gap of network by proximal end to being distally gradually reduced, density matches
The mesh design of conjunction guarantees that bracket can quickly be embedded in combination and fishing capacity endovascular while that increase bracket and thrombus；
Furthermore the density for increasing distal stent grid can effectively prevent broken small Thromboembolus to fall off from bracket and reduce bracket and pass through
To the damage of vascular wall when blood vessel；The distal end of last bracket is provided with spring, increases the flexibility for taking bolt bracket；Finally by
The cooperation for pushing handle casing and pushing hands, improves the operability for taking bolt bracket.
Detailed description of the invention
Fig. 1 is the structural schematic diagram provided by the invention for taking pin device；
Fig. 2 is the structural schematic diagram of superlastic silk at anchor point provided by the invention；
Fig. 3 is the structural schematic diagram of woven mesh bracket of the present invention；
Fig. 4 takes pin device to take bolt process schematic to be provided by the invention；
Fig. 5 is the structural schematic diagram of the push handle provided by the invention for taking pin device；
Fig. 6 is the structural schematic diagram that pushing hands sliding takes bolt bracket.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described,
Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention
Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all
Belong to the scope of protection of the invention.
The present invention provides one kind to take pin device, comprising:
Take bolt bracket, transportation system and push handle；
Described to take bolt bracket include network and spring, and the grid gap of described network one end is less than the other end
Grid gap；The network gap is provided with spring at the top of small one end；
The transportation system includes mandrel and the outer tube for mandrel traveling；
The mandrel runs through entire outer tube and network；
The top fixation of the big one end in network grid gap is collected in one end of outer tube；
The push handle includes shell and pushing hands；
Slideway is provided on the shell；The pushing hands is set in slideway, and can be slided along slideway；
The shell is connected with the other end of outer tube, and the pushing hands is connected with the other end of mandrel；
Or the shell is connected with the other end of mandrel, the pushing hands is connected with the other end of outer tube.
Referring to Fig. 1, Fig. 1 is the structural schematic diagram provided by the invention for taking bolt bracket, wherein 1 is network, 2 be core
Axis, 3 be outer tube, and 4 be developing ring, and 5 be spring, and 6 be shell, and 7 be pushing hands.
According to the present invention, described to take bolt bracket include network and spring；The network is those skilled in the art
Network known to member, has no special limitation, and the grid cell of heretofore described network is surrounded by twine,
The twine is preferably wound by 1 strand or 1 strand or more of monofilament, more preferably winds shape by 2 strands or 2 strands or more of monofilament
At；The twine is preferably made of the twine lattice unit that monofilament is wound density interphase；The network is preferably by having
Memory capability, the alloy material of elasticity and/or high molecular material are formed；It is described in order to improve the whole developability of network
Network preferably includes visible metal material under X-ray, more preferably one of gold, platinum, tantalum, platinumiridio and barium sulfate
Or it is a variety of；The network can cut to obtain for tubing, can also be woven by superlastic silk, it is preferably by surpassing in the present invention
The staggered supporting structure of forward-reverse spiral made of elater braiding；Network integrally uses helical structure to design, and increases bracket
Flexibility, reduce scratch when passing through curved blood vessel to vascular wall, in addition network is obtained by being cross-woven, and can also be made close
Hold manipulation effect more preferable；The network can be woven back and forth by single superlastic silk, can also by the braiding of more superlastic silks and
At；When the network is woven back and forth by single superlastic silk, round-trip number is preferably 4 multiple；When by more
When superlastic silk weaves, the radical of the superlastic silk is preferably 3 multiple, while making each grid intersection and have 4
Superlastic silk crossed loops without restriction around and moving freely；The superlastic silk is superlastic silk well known to those skilled in the art, and
Without special limitation, a preferably at least inside is visible metal material under X-ray in the present invention, and outside package is super-elasticity
Material, can be hyperelastic alloy material such as Nitinol, also be with memory capability, elasticity high molecular material so that
Entire network has can developability.
The grid gap of described network one end is less than the grid gap of the other end；In medical instrument, normal operating
When, it is distal end apart from remote the contacting first with patient of doctor that one end close apart from doctor, which is proximal end, i.e. netted in the present invention
The grid gap of rack far end is less than the grid gap of proximal end, forms it into grid gap and is gradually reduced by proximal end to distal end；?
Relaxed state, the small parts transversely spacing in the network gap are 1~5mm；The big portion in network grid gap
Dividing horizontal spacing is preferably 1.2~3 times of the small parts transversely spacing in gap, and more preferably 1.2~2.5 times, be further preferably 1.2
~2 times；The length of grid gap fraction and the ratio of grid gap major part length are preferably 1:(0.5~5), it is more excellent
It is selected as 1:(1~5), be further preferably 1:(2~4), most preferably 1:(2.5~3)；The length of the network is preferably 10~
200mm；The diameter of the network is preferably 0.5~40mm, more preferably 0.5~30mm, is further preferably 0.5~20mm,
It is further preferably 2~20mm, is further preferably 2~10mm, is further preferably 2~8mm, most preferably 2~5.5mm.
According to the present invention, the second developing ring is further preferably provided between the network and spring；Second development
Ring is developing ring well known to those skilled in the art, has no special limitation.First be arranged by network both ends
Developing ring and the second developing ring can show the working region of network under X-ray.
The small one end in network grid gap can be fixed to collect also to fix in the second developing ring and collect in bullet
In spring；It is preferably 2~20mm that the fixation, which is collected in the length in the second developing ring or spring, more preferably 5~15mm, then excellent
It is selected as 8~10mm；The spring is spring well known to those skilled in the art, has no special limitation；The spring is not
The one end contacted with network is preferably closed using smooth material；The top of the smooth material is preferably arc-shaped；It is described
The length of spring is preferably 5~20mm, more preferably 10~20mm, is further preferably 15mm；The outer diameter of the spring is preferably
0.01~0.02 inch, more preferably 0.012~0.019 inch；The internal diameter of the spring is preferably 0.005~0.02 inch,
More preferably 0.01~0.016 inch.
It is provided by the invention that take pin device include transportation system；The transportation system includes mandrel and advances for mandrel outer
Pipe；The big one end in network grid gap is fixed in outer tube；The outer tube is well known to those skilled in the art outer
Pipe has no special limitation, is preferably woven tube or macromolecule tubing in the present invention.The diameter of the outer tube is preferably
0.1~2.5mm, more preferably 0.5~2mm are further preferably 0.5~1mm；The length of the outer tube is preferably 20~300cm, more
Preferably 50~250cm is further preferably 100~250cm, is further preferably 150~200cm, most preferably 180cm.
It is described to take bolt bracket it is also preferable to include the first developing rings according to the present invention；First developing ring is set to netted
Between bracket and outer tube, and it is preferably fixed on outer tube；First developing ring is that the known developing ring of those skilled in the art is
Can, have no special limitation.
It is provided with mandrel in the outer tube, and can freely advance in outer tube；The mandrel through entire outer tube with it is netted
Bracket, and one end of the mandrel is fixed with the small one end, that is, network distal end in network grid gap and is collected in second
In developing ring or spring；By movement of the mandrel in outer tube, network can be pushed and pulled and generate deformation, and then realize network
The change of diameter；The mandrel is preferably Nitinol, stainless steel or other hardness suitable metal silks or metal tube.
It is provided by the invention that pin device is taken to include push handle；The push handle includes shell and pushing hands；In the present invention
Described in shell be preferably molded and formed by high molecular material with pushing hands.Slideway is provided on the shell；The pushing hands setting
In in slideway, and can be slided along slideway；The other end of the shell and outer tube, i.e., the one end not contacted with network are connected
It connects, the pushing hands is that the one end not contacted with network is connected with the other end of mandrel；Or the shell and mandrel
The other end is connected, and the pushing hands is connected with the other end of outer tube；So as to pass through by the opposite sliding of pushing hands and shell
It advances and retreats the contraction or expansion for driving network, achievees the purpose that stent diameter is controllable.
The relative movement distance and network of pushing hands and shell expansion with shrink when length difference, the difference with
The diameter of network there are corresponding linear relationship, for convenience of operator can intuitive judgment bracket opening situation, it is described outer
It is preferably provided with scale along slideway on shell, i.e., is provided with scale on the stroke of pushing hands, which corresponds to network variation
Numerical value.
It is hand-held for convenience of operator, operational difficulty, the preferably imitative ergonomics of the shell are reduced to greatest extent
Design.
The present invention makes to take bolt bracket that can be adjusted according to the diameter of diseased region blood vessel by movement of the mandrel in outer tube
Section, improves the matching for taking bolt bracket and lesion vessels；Meanwhile the grid gap of network by proximal end to distally gradually contracting
Mesh design small, that density matches guarantees that bracket can quickly be embedded in combination that is endovascular while increasing bracket and thrombus
And fishing capacity；Furthermore the density for increasing distal stent grid, can effectively prevent broken small Thromboembolus to fall off from bracket；Most
The distal end of after-poppet collects in spring, increases the flexibility for taking bolt bracket；Finally by push handle casing and pushing hands
Cooperation, improves the operability for taking bolt bracket.In conclusion provided by the invention, to take pin device be that a kind of structure setting passes through
Ability is good, and bracket operation row is strong, is not easy to shift, and arrests that thrombus range is wide, removal of thromboses controllable taking thrombus not easily to fall off
Device.
The present invention also provides a kind of above-mentioned preparation methods for taking network in pin device, comprising:
Using cylindric or columned bracket sizing tooling；The surface of the bracket sizing tooling is provided with spiral
The a plurality of anchor point of distribution；
One end of superlastic silk is fixed on to one end of bracket sizing tooling, is then advanced along anchor point, braiding obtains net
Shape supporting structure；The grid gap of network structure one end is less than the grid gap of the other end；
The network structure heat-shaping is obtained into network after cooling.
The present invention weaves superlastic silk using cylindric or columned bracket sizing tooling；Tooling is used in the bracket sizing
It is preferred that being formed by materials with high melting point, more preferably by one of copper, stainless steel and ceramics or a variety of formation；The bracket sizing is used
The surface of tooling is provided with a plurality of anchor point of Spiral distribution；The anchor point is preferably right-handed screw and/or backpitch distribution；Institute
The item number for stating anchor point Spiral distribution is preferably 3~6, and more preferably 3~4, be further preferably 3；Also, it can be by adjusting
The density of arbitrary region anchor point distribution, can adjust the gap size of the network of braiding.
One end of superlastic silk is fixed on to one end of bracket sizing tooling, is then advanced along anchor point, braiding；It is described super
Elater also can be more superlastic silks for single superlastic silk, and when using single superlastic silk, branch is fixed in one end of superlastic silk
One end of tooling is used in frame sizing, is then advanced, is preferably advanced according to sinuous path, and in adjacent anchor point superlastic along anchor point
Silk is located at the two sides of anchor point, can not be starting point back along phase using the anchor point after marching to the last one anchor point ipsilateral
Anti- path is advanced along cosine path direction, adjacent positioned point superlastic silk is located at the two sides of anchor point equally on path, such as
This reciprocal knitting is loaded onto form the staggered network structure of forward-reverse spiral in bracket sizing recruitment；Each anchor point is excellent
Choosing has 4 superlastic silk crossed loops around four interlaced superlastic silks can be free to slide without restricting at anchor point.At anchor point
The structural schematic diagram of superlastic silk is as shown in Figure 2 a, and wherein black dot is anchor point；Fig. 3 is the structural representation of woven mesh bracket
Figure, weaves by adjusting arbitrary region anchor point density.
When the superlastic silk is more superlastic silks, the number of the superlastic silk is preferably that anchor point forms spiral bar number
Multiple more preferably forms 4 times of spiral bar number；It specifically weaves according to the following steps: taking superlastic silk identical with spiral bar number,
It is fixed on one end of bracket sizing tooling, the other end is advanced along anchor point sinuous path spiral, and the adjacent positioned on path
Superlastic silk is located at the two sides of anchor point at point, fixes after marching to the tooling other end；Superlastic silk identical with spiral bar number is taken again,
It is fixed on identical starting point, the other end is advanced along anchor point cosine path spiral, and adjacent positioned point makes superlastic silk on path
Positioned at the two sides of anchor point, fixed after marching to the other end；It repeats the above steps after the traveling of sinuous path spiral, then by superlastic
Silk is advanced along cosine path spiral, makes each anchor point and have 4 superlastic silk crossed loops around obtaining network structure.
The present invention also provides a kind of preparation methods of above-mentioned network, comprising:
By braider or tooling by two superlastic silk winding braidings, is handled using thermal finalization, obtain twine.
Twine is woven to obtain network structure by braider；
The superlastic silk is same as above, and details are not described herein；The superlastic silk preferably elastic alternate braiding is formed to have and be dredged
The structure of close alternate twine unit, as shown in Figure 2 b.
Thermal finalization is handled after braiding, obtains twine；The condition of the thermal finalization is same as above, and details are not described herein.
Twine is woven to obtain network structure by braider, as shown in Figure 2 c；The grid of the network structure
Gap, length and diameter are same as above, and details are not described herein.
The network structure heat-shaping is obtained into network after cooling；The temperature of the heat-shaping is preferred
It is 400 DEG C~510 DEG C；The time of the heat-shaping is preferably 1~15min.
In the present invention, it can also be cut on tubing by laser and obtain network structure；The tubing is this field
Tubing known to technical staff has no special limitation；Such as it is less than the network for needing to obtain using the diameter of tubing
The diameter of structure after cutting, preferably by mold expansion diameter, obtains network structure.
The grid gap of the network structure, length and diameter are same as above, and details are not described herein.
The network structure heat-shaping is obtained into network after cooling；The temperature of the heat-shaping is preferred
It is 400 DEG C~510 DEG C；The time of the heat-shaping is preferably 1~15min.
In order to further illustrate the present invention, pin device is taken to carry out in detail one kind provided by the invention with reference to embodiments
Description.
Reagent used in following embodiment is commercially available.
Embodiment 1
Network length 30mm, stent diameter 5.5mm；Outer length of tube 180cm；Outer tube diameter 0.60mm.
The present embodiment matches 0.021 inch of microtubular of internal diameter, bracket work zone length 30mm, diameter 5.5mm with size.
Specifically, the superlastic silk of bolt bracket is taken to choose diameter as 0.004 inch (0.0102mm) containing 30% platinum for weaving
The nitinol alloy wire that can integrally develop.Multifibres is taken to weave preparation method, weaver sets the sparse parts transversely interval in site
7mm, extensive part lateral separation 5mm, sparse part are 3:1 with extensive part length ratio, are woven into working region with 12 silks
Length 30mm, the network of working diameter 5.5mm are 1., stand-by after heat treatment shaping.2. mandrel selects 0.007 inch of diameter
3. nitinol alloy wire, outer tube select the nylon tube of 0.02 inch of outer diameter, 0.015 inch of internal diameter.By 0.023 inch of outer diameter, internal diameter
0.02 inch, 4. the developing ring of long 1mm is fixed on the outside of distal outer tube.Remove the good network of heat treatment shaping 1., it will
3. the raw silk rings part of the network 1. superlastic silk of proximal end 12, which is collected, to be connected one end inner cavity of developing ring 4. in outer tube and fixes.Bracket
1. 4. distal end and developing ring link together, and mandrel is 2. 1. internal through bracket, 4. it is pierced by from distal end developing ring.Exceed
2. distal end developing ring superlastic silk 4. and mandrel retain 10mm length.Choose 0.019 inch of outer diameter, 0.016 inch of internal diameter, length
5., by the superlastic silk of above-mentioned 10mm length the spring of 15mm collects with mandrel that 5. inner cavity is fixed in spring, in the distal end of spring 5.
Using smooth material closing spring opening and arc-shaped is formed on top, constitutes the distal end for entirely taking bolt bracket, passes through arc-shaped
The Combination Design of smooth top and spring can increase the flexibility for taking bolt rack far end, have it with blood vessel and preferably comply with
Property, the stimulation to vascular wall is reduced during taking pin device to discharge can prevent from taking especially in the curved vessel segment of detour
Pin device punctures blood vessel and the accident that causes.
6. push handle casing is imitative ergonomic designs, facilitate operator hand-held, reduce to greatest extent operational
Difficulty, by the outer tube of transportation system, 3. 6. proximal end links together with shell, 2. 7. the mandrel of transportation system connects with pushing hands respectively
It is connected together.Pushing hands is the difference for taking bolt stent expansion with stent length when shrinking at a distance from 7. 6. relatively moving with shell,
There are corresponding linear relationships with stent diameter for the difference, further, as shown in figure 5, in the stroke of handle casing pushing hands
On mark the numerical value of corresponding stent diameter variation, facilitate doctor that can intuitively judge the opening situation of bracket, Fig. 5 is push
The structural schematic diagram of handle, wherein 1 is shell, 2 be pushing hands, and 3 be slideway；Fig. 6 is the structural representation that pushing hands sliding takes bolt bracket
Figure.
Embodiment 2
Below to match 0.013 inch of microtubular of internal diameter, bracket work zone length 20.5mm, diameter 2mm are applicable in blood vessel
Diameter 0.5mm~2.5mm makes further supplement to use scope of the invention.
Specifically, the superlastic silk of bolt bracket is taken to choose diameter as 0.004 inch (0.0102mm) containing 30% platinum for weaving
The nitinol alloy wire that can integrally develop.Multifibres is taken to weave preparation method, weaver sets the sparse parts transversely interval in site
2mm, extensive part lateral separation 1mm, sparse part and the length ratio of extensive part are 2.5:1, are woven into work with 12 silks
Make zone length 20.5mm, the network of diameter 2mm is 1., stand-by after heat treatment shaping.2. mandrel selects 0.005 inch of diameter
Nitinol alloy wire, 3. outer tube selects the nylon tube of 0.012 inch of outer diameter, 0.010 inch of internal diameter.By 0.014 inch of outer diameter, interior
0.012 inch of diameter, 4. the developing ring of long 1mm is fixed on the outside of distal outer tube.Remove the good network of heat treatment shaping 1.,
The raw silk rings part of the bracket 1. superlastic silk of proximal end 12 is collected and 3. connects one end inner cavity of developing ring 4. in outer tube and fixes.Bracket is 1.
4. distal end and developing ring link together, and mandrel is 2. 1. internal through bracket, are 4. pierced by from distal end developing ring.Beyond remote
2. end developing ring superlastic silk 4. and mandrel retain 10mm length.Choose 0.012 inch of outer diameter, 0.010 inch of internal diameter, length
5., by the superlastic silk of above-mentioned 10mm length the spring of 15mm collects with mandrel that 5. inner cavity is fixed in spring, in the distal end of spring 5.
Using smooth material closing spring opening and arc-shaped is formed on top, constitutes the distal end for entirely taking pin device, passes through arc-shaped
The Combination Design of smooth top and spring can increase the flexibility for taking pin device distal end, have it with blood vessel and preferably comply with
Property, the stimulation to vascular wall is reduced during taking pin device to discharge can prevent from taking especially in the curved vessel segment of detour
Pin device punctures blood vessel and the accident that causes.Sending handle casing 6. is imitative ergonomic designs, facilitates operator hand-held, maximum
Limit reduces operational difficulty.The method different with embodiment 1 can be used in supplying system and the connection of handle, it respectively will be defeated
Send the outer tube of system 3. proximal end with pushing hands 7., the mandrel of transportation system 2. 6. link together with shell, pushing hands 7. with shell 6.
The distance of relative movement is the difference of stent length when taking bolt stent expansion and shrinking, and the difference and stent diameter exist opposite
The linear relationship answered, further, as shown in figure 5, marking corresponding stent diameter variation on the stroke of handle casing pushing hands
Numerical value, facilitate doctor that can intuitively judge the opening situation of bracket.
The present embodiment is small compared with same device on the market by 80%, leads by the way that the neural blood vessel of soft distal outer diameter 1.3Fr is micro-
Pipe is sent into, and to the intracranial vessel of 0.5mm~2.5mm carries out that bolt is taken to operate.The vascular occlusion of this kind of caliber accounts for patients with cerebral apoplexy
30%, other machinery can not treat on the market.
The present invention takes the application method embodiment of pin device as follows:
When interventional therapy, intracranial vessel lesion locations are determined by angiography first, it is then dynamic from femoral artery or the upper arm
Arteries and veins punctures and is put into vagina vasorum, and guiding wire and microtubular are alternately pushed and are placed into diseased region front end, withdraws from guiding wire,
Bolt bracket will be taken to be put into diseased region along microtubular, as shown in fig. 4 a, take bolt rack far end all to pass through thrombus, during which take
Bolt bracket is in contraction state always situated in microtubular.It stretches mandrel or pushes outer tube, open network, such as Fig. 4 b
It is shown, thrombus is incorporated, recline vascular wall.As illustrated in fig. 4 c, using the taking thrombus bracket and microtubular that incorporate thrombus as one
It is whole slowly to pull out, take bolt bracket integrally to withdraw from outside human body, completion takes bolt process.
Embodiment of the method description used above is directed to intracranial vessel and takes bolt, is only exemplary, pin device is taken to close
Also other be may adapt under suitable size and intravascular take bolt.
Claims (10)
1. one kind takes pin device characterized by comprising
Take bolt bracket, transportation system and push handle；
Described to take bolt bracket include network and spring, and the grid gap of described network one end is less than the net of the other end
Compartment gap；The network gap is provided with spring at the top of small one end；
The transportation system includes mandrel and the outer tube for mandrel traveling；
The mandrel runs through entire outer tube and network；
The top fixation of the big one end in network grid gap is collected in one end of outer tube；
The push handle includes shell and pushing hands；
Slideway is provided on the shell；The pushing hands is set in slideway, and can be slided along slideway；
The shell is connected with the other end of outer tube, and the pushing hands is connected with the other end of mandrel；
Or the shell is connected with the other end of mandrel, the pushing hands is connected with the other end of outer tube.
2. according to claim 1 take pin device, which is characterized in that further include the first developing ring and the second developing ring；Institute
The first developing ring is stated to be set between network and outer tube；Second developing ring is set between network and spring.
3. according to claim 1 take pin device, which is characterized in that the small parts transversely in network grid gap
Spacing is 1~5mm；The big parts transversely spacing in network grid gap is between the small parts transversely in network gap
Away from 1.2~3 times.
4. according to claim 1 take pin device, which is characterized in that adopt one end that the spring is not contacted with network
It is closed with smooth material, and the top of the smooth material is arc-shaped.
5. according to claim 1 take pin device, which is characterized in that the network is as made of the braiding of superlastic silk
The staggered supporting structure of forward-reverse spiral.
6. according to claim 5 take pin device, which is characterized in that the superlastic silk includes visible metal material under X-ray
Material.
7. according to claim 1 take pin device, which is characterized in that the network is prepared according to the following steps:
Using cylindric or columned bracket sizing tooling；The surface of the bracket sizing tooling is provided with Spiral distribution
A plurality of anchor point；
One end of superlastic silk is fixed on to one end of bracket sizing tooling, is then advanced along anchor point, braiding obtains netted branch
Frame structure；The grid gap of network structure one end is less than the grid gap of the other end；
The network structure heat-shaping is obtained into network after cooling.
8. according to claim 1 take pin device, which is characterized in that the network is prepared according to the following steps:
It is cut on tubing by laser and obtains network structure；
The grid gap of network structure one end is less than the grid gap of the other end；
The network structure heat-shaping is obtained into network after cooling.
9. according to claim 7 or 8 take pin device, which is characterized in that the temperature of the heat-shaping be 400 DEG C~
510℃；The time of the heat-shaping is 1~15min.
10. according to claim 1 take pin device, which is characterized in that slideway is provided with scale on the shell.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811331717.9A CN109223107B (en) | 2018-11-09 | 2018-11-09 | Bolt taking device |
| CN202410289753.2A CN118105136A (en) | 2018-11-09 | 2018-11-09 | Bolt taking device |
| CN202410289772.5A CN118000834A (en) | 2018-11-09 | 2018-11-09 | Bolt taking device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811331717.9A CN109223107B (en) | 2018-11-09 | 2018-11-09 | Bolt taking device |
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|---|---|---|---|
| CN202410289753.2A Division CN118105136A (en) | 2018-11-09 | 2018-11-09 | Bolt taking device |
| CN202410289772.5A Division CN118000834A (en) | 2018-11-09 | 2018-11-09 | Bolt taking device |
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| Publication Number | Publication Date |
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| CN109223107A true CN109223107A (en) | 2019-01-18 |
| CN109223107B CN109223107B (en) | 2024-04-02 |
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| CN202410289753.2A Pending CN118105136A (en) | 2018-11-09 | 2018-11-09 | Bolt taking device |
| CN201811331717.9A Active CN109223107B (en) | 2018-11-09 | 2018-11-09 | Bolt taking device |
| CN202410289772.5A Pending CN118000834A (en) | 2018-11-09 | 2018-11-09 | Bolt taking device |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109771097A (en) * | 2019-03-11 | 2019-05-21 | 北京航空航天大学 | Manpower intervention type aortic valve stent with the variation of radial support power |
| CN112168286A (en) * | 2020-11-16 | 2021-01-05 | 杭州诺礼医疗器械有限公司 | Thrombectomy support, thrombectomy device and thrombectomy system |
| CN112294394A (en) * | 2019-07-24 | 2021-02-02 | 西安交通大学医学院第一附属医院 | Adjustable peripheral blood vessel thrombus taking support assembly |
| CN113520519A (en) * | 2021-04-30 | 2021-10-22 | 常州凯尼特医疗科技有限公司 | Adjustable bracket type bolt taking device |
| WO2023050521A1 (en) * | 2021-09-29 | 2023-04-06 | 北京泰杰伟业科技有限公司 | Combined control thrombectomy device |
| CN116942255A (en) * | 2023-09-18 | 2023-10-27 | 北京华脉泰科医疗器械股份有限公司 | Thrombus removing device |
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Also Published As
| Publication number | Publication date |
|---|---|
| CN118105136A (en) | 2024-05-31 |
| CN109223107B (en) | 2024-04-02 |
| CN118000834A (en) | 2024-05-10 |
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