CN109771097A - Manpower intervention type aortic valve stent with the variation of radial support power - Google Patents
Manpower intervention type aortic valve stent with the variation of radial support power Download PDFInfo
- Publication number
- CN109771097A CN109771097A CN201910181781.1A CN201910181781A CN109771097A CN 109771097 A CN109771097 A CN 109771097A CN 201910181781 A CN201910181781 A CN 201910181781A CN 109771097 A CN109771097 A CN 109771097A
- Authority
- CN
- China
- Prior art keywords
- aortic valve
- network
- valve stent
- manpower intervention
- type aortic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses the variable diameters of manpower intervention type aortic valve stent to support force optimization method.The optimization method belongs to the technical field of manpower intervention type aortic valve stent optimization.It specifically includes: the optimization of bracket network, the structure optimization of bracket muscle and timbering material optimization.Optimization method principle of the present invention is simple, have not been changed former standoff overall dimensions, inherit former standoff core design theory and method, it is not changed to the radial support power for optimizing non-lesion region on the basis of lesion region therapeutic effect, and diversified prioritization scheme, multi-angle multi-scheme solving practical problems can be selected according to the difference of practical application scene.Meanwhile optimization method feasibility is higher.Scientific and reasonable mentality of designing and R&D direction are provided to be engaged in the vast researcher of manpower intervention type aortic valve stent design, shortens the R&D cycle, improves research and development benefit.
Description
Technical field
The present invention relates to the technical fields of manpower intervention type aortic valve stent optimization, refer specifically to manpower intervention type master
The variable diameter of artery valve bracket is to support force optimization method.
Background technique
Aorta petal plays the role of one-way cock between left ventricle and aorta ascendens, can hold in paradoxical expansion
It puts to allow the blood of left ventricle swimmingly to inject aorta ascendens, and can be closed in diastole, to guarantee aorta ascendens
Blood will not flow back into left ventricle.If there is lesion in aorta petal, such as: it cannot be opened completely when heart contraction (narrow
It is narrow), left ventricular ejection just will appear obstruction, or be unable to completely close (incompetence) in diastole, and directive rises master
The blood of artery will reversely flow back to left ventricle, can all make the function reduction of heart, and lead to whole body blood supply insufficiency, and patient can go out
Existing dizzy, out of strength, uncomfortable in chest, palpitaition etc..
It is one through conduit aortic valve replacement (Transcatheter Aortic Valve Replacement, TAVR)
Kind microtrauma type valve replacement surgery, is that heart valve prosthesis is delivered to aortic valve position and is released by interposing catheter technology
It puts, to complete artificial valve implantation, substitutes original diseased valve, realize its proper function.Manpower intervention type aortic valve
Bracket provides structural support effect for leaflet therein, and lesion narrow zone can be strutted by radial force, and anchoring is whole
Structure is to target lesion position.At present in support Design, the preferential larger radial support power for ensureing lesion region is to meet to narrow
The extension and anchoring in narrow region act on, and due to the global consistency of timbering material and network, bracket is in the non-disease of aorta ascendens
Become region and be also provided that biggish radial support power, may cause non-lesion region and generate new lesion.
Summary of the invention
According to an aspect of the invention, there is provided a kind of radial support power for mediatory type aortic valve stent is excellent
Change method, characterized by comprising:
Make mediatory type aortic valve stent that there is the network of unit repeatability,
Make the mesh-density in the non-lesion region of the network than the lesion region mesh-density of the network
It is small.
According to another aspect of the present invention, a kind of manpower intervention type aortic valve stent is provided, it is characterised in that
Include:
Network with unit repeatability,
Wherein:
The mesh-density in the non-lesion region of the network is smaller than the lesion region mesh-density of the network.
Detailed description of the invention
Fig. 1 is the variable diameter of manpower intervention type aortic valve stent of the present invention to support force optimization method schematic diagram.
Appended drawing reference:
LRBracket muscle structure longitudinal edge；
LCBracket muscle structure peripheral edge.
Specific embodiment
The present invention proposes bracket the service condition of above-mentioned manpower intervention type aortic valve and aiming at the problem that encounter
Variable diameter guarantees that bracket provides enough radial supports in lesion region and supports out narrow zone, anchoring certainly to support force optimization method
While body, changes bracket to the radial support power in non-lesion region, in order to avoid destroying vascular wall tissue, generate new lesion.
The variable diameter includes that bracket network optimizes to support force optimization method, the structure optimization of bracket muscle and timbering material
Optimization.
The bracket network optimization: bracket includes the gridding structure of unit repeatability.It is specified by adjusting bracket
The mesh-density in region changes the radial support power in the bracket region.
The muscle structure optimization: the section of bracket muscle structure is rectangle, and four sides are divided into the circumferential direction for being parallel to bracket circumferential direction
Side and the longitudinal edge for being parallel to bracket radial direction.Change by adjusting the peripheral edge size or longitudinal edge size in bracket non-lesion region
The area of section of bracket muscle structure further changes the radial support power of the region bracket.
The timbering material optimization: bracket is generally made of nickel-titanium alloy material, has good shape memory function.?
The method that bracket non-lesion region adjusts material properties using other memory alloy materials etc. changes the radial branch of the region bracket
Support force.
The optimization method, which can be used alone, also can be used in combination, specifically used method can according to concrete application scene into
Row selection.In conjunction with the increasing material manufacturings such as 3D printing being constantly progressive technique, it can be achieved that above-mentioned optimization method.
The present invention has the advantages that
1) former standoff overall dimensions are had not been changed, former standoff core design theory and method is inherited, does not change
It can both reduce bracket to non-lesion area to the radial support power for optimizing non-lesion region on the basis of lesion region therapeutic effect
The damage in domain can also increase the radial support power in bracket region, meet requirement used in connection with according to application scenarios difference.
2) principle of optimality is relatively simple, optimizes in terms of three, and both can be used alone a kind of optimization method, can also root
A variety of optimization methods are used according to actual conditions, to realize different effect of optimization.
3) optimization method feasibility is higher, can realize prioritization scheme by kinds of processes, wherein relies on 3D printing etc. constantly
Fast-developing increasing material manufacturing technique realizes that related prioritization scheme is more efficient, and feasibility is stronger.
Below with reference to drawings and examples, the present invention is described in further detail.
The invention discloses the variable diameters of manpower intervention type aortic valve stent to support force optimization method, by adjusting branch
Network, bracket muscle structure or timbering material in frame region, change the radial support power in bracket region, and optimization is artificial
The military service effect of mediatory type aortic valve.
The bracket network optimization refers to specifies the mesh-density in region to change bracket in the area by adjusting bracket
The radial support power in domain.As shown in Figure 1, bracket includes the gridding structure of unit repeatability.Wherein, make the non-lesion area of bracket
Domain mesh-density becomes smaller, and size of mesh opening becomes larger, and/or by the variation of geometry, changes the grid in per unit contact area
Muscle content, to reduce the radial support power of the region bracket；For needing to increase the narrow zone of radial support power, pass through increasing
Big bracket mesh-density, improves the region radial support power of bracket.
Muscle structure optimization refers to specifies the size of muscle structure in region to change the radial direction in the bracket region by adjusting bracket
Support force.The section of bracket muscle structure is rectangle, and four sides are divided into the peripheral edge L for being parallel to bracket circumferential directionCBe parallel to bracket
Radial longitudinal edge LR, by adjusting the peripheral edge L in bracket non-lesion regionCSize or longitudinal edge LRSize changes bracket muscle knot
The area of section of structure further changes the radial support power of the region bracket.Area of section is bigger, and radial support force is got in region
Greatly；Area of section is smaller, and radial support force is smaller in region.As bracket muscle structure peripheral edge LCSize is greater than longitudinal edge LRSize
When, cradle fits vascular wall effect is more preferable.
Timbering material optimization refers to the material by adjusting specified region inner support muscle to change the diameter of the region inner support
To support force.Bracket is generally made of nickel-titanium alloy material, has good shape memory function.It can produce at a lower temperature
Raw plastic deformation, restores its original form and mechanical property at relatively high temperatures, is very beneficial for manpower intervention type aorta petal
The conveying and release of film.It is specified in bracket and adjusts the material properties of bracket muscle in region to change the radial branch of region inner support
Support force.
According to one embodiment of present invention, the network is by the Nitinol with good shape memory function
Material is made, and the nickel-titanium alloy material generates plastic deformation at a temperature of 0~4 DEG C, restores its original at a temperature of 25~37 DEG C
There are form and mechanical property.
The optimization method, which can be used alone, also can be used in combination, specifically used method can according to concrete application scene into
Row selection.Individually using certain described optimization method, degree of optimization and effect are feasible to a certain extent, a variety of optimization sides
Method, which is used in combination, can be achieved effect of optimization superposition, can expand degree of optimization and effect.Can according to specific usage scenario or
Situation takes the circumstances into consideration to select.
Optimization method principle belonging to the present invention is simple, has not been changed former standoff overall dimensions, inherits former standoff
Core design theory and method do not change it to the radial support for optimizing non-lesion region on the basis of lesion region therapeutic effect
Power, and different prioritization schemes can be selected according to the difference of practical application scene, multi-angle multi-scheme solving practical problems.Together
When, optimization method feasibility is higher, can realize prioritization scheme by kinds of processes, wherein 3D printing etc. is relied on constantly quickly to send out
The increasing material manufacturing technique of exhibition realizes that related prioritization scheme is more efficient, and feasibility is stronger.
Claims (8)
1. being used for the radial support power optimization method of mediatory type aortic valve stent, characterized by comprising:
Make mediatory type aortic valve stent that there is the network of unit repeatability,
Keep the mesh-density in the non-lesion region of the network smaller than the lesion region mesh-density of the network.
2. being used for the radial support power optimization method of mediatory type aortic valve stent as described in claim 1, feature exists
In:
Make the muscle structure of the network that there is the section of rectangle, the four edges of the rectangle include being parallel to manpower intervention type
The circumferential peripheral edge L of aortic valve stentCWith the radial longitudinal edge for being parallel to manpower intervention type aortic valve stent
LR,
It is greater than the area in the section in the lesion region of the network in the non-lesion area of the network
The area in the section in domain.
3. being used for the radial support power optimization method of mediatory type aortic valve stent as claimed in claim 2, feature exists
In:
Make the bracket muscle structure peripheral edge L in the lesion region of the networkCSize be greater than longitudinal edge LRSize.
4. the radial support power optimization method for mediatory type aortic valve stent as described in one of claim 1-3,
It is characterized in that:
The network is made with the nickel-titanium alloy material with good shape memory function,
Wherein:
The nickel-titanium alloy material generates plastic deformation at a temperature of 0~4 DEG C, restores its original form at a temperature of 25~37 DEG C
And mechanical property.
5. a kind of manpower intervention type aortic valve stent, characterized by comprising:
Network with unit repeatability,
Wherein:
The mesh-density in the non-lesion region of the network is smaller than the lesion region mesh-density of the network.
6. manpower intervention type aortic valve stent as claimed in claim 5, it is characterised in that:
The section of the muscle structure of the network is rectangle, and four sides include being parallel to manpower intervention type aortic valve stent
Circumferential peripheral edge LCWith the radial longitudinal edge L for being parallel to manpower intervention type aortic valve stentR,
The area in the section in the lesion region of the network is greater than in the non-lesion region of the network
In the section area.
7. manpower intervention type aortic valve stent as claimed in claim 6, it is characterised in that:
Bracket muscle structure peripheral edge L in the lesion region of the networkCSize be greater than longitudinal edge LRSize.
8. the manpower intervention type aortic valve stent as described in one of claim 5-7, it is characterised in that:
The network is made of the nickel-titanium alloy material with good shape memory function,
The nickel-titanium alloy material generates plastic deformation at a temperature of 0~4 DEG C, restores its original form at a temperature of 25~37 DEG C
And mechanical property.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910181781.1A CN109771097A (en) | 2019-03-11 | 2019-03-11 | Manpower intervention type aortic valve stent with the variation of radial support power |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910181781.1A CN109771097A (en) | 2019-03-11 | 2019-03-11 | Manpower intervention type aortic valve stent with the variation of radial support power |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109771097A true CN109771097A (en) | 2019-05-21 |
Family
ID=66488850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910181781.1A Pending CN109771097A (en) | 2019-03-11 | 2019-03-11 | Manpower intervention type aortic valve stent with the variation of radial support power |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109771097A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111407466A (en) * | 2020-03-27 | 2020-07-14 | 山东大学齐鲁医院 | Implantable biological valve |
Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201001791Y (en) * | 2007-02-12 | 2008-01-09 | 孔祥清 | Stent for reducing left ventricular mitral back-flow and its conveying device |
| CN101606869A (en) * | 2009-07-13 | 2009-12-23 | 成正辉 | Cerebral aneurysm endovascular plastic repair bracket and conveyer device thereof |
| US20100256732A1 (en) * | 2008-10-16 | 2010-10-07 | Kyong-Min Shin | Wavily deformable stent and method for producing the same |
| CN101991477A (en) * | 2009-08-27 | 2011-03-30 | 微创医疗器械(上海)有限公司 | Vascular reconstructive support frame |
| CN202724037U (en) * | 2012-08-01 | 2013-02-13 | 吕文峰 | Support and conveying system thereof for treating arterial aneurysm |
| CN203885667U (en) * | 2014-06-06 | 2014-10-22 | 微创神通医疗科技（上海）有限公司 | Stent |
| CN204133642U (en) * | 2014-06-25 | 2015-02-04 | 北京奇伦天佑创业投资有限公司 | The support of overlay film frame and the implant system implanted respectively with overlay film thereof |
| CN104736107A (en) * | 2012-10-25 | 2015-06-24 | W.L.戈尔及同仁股份有限公司 | Stent with varying cross-section |
| CN105287051A (en) * | 2015-09-30 | 2016-02-03 | 复旦大学附属中山医院 | Artificial aortic valve ring system implanted through peripheral arterial approach |
| CN205031392U (en) * | 2015-09-25 | 2016-02-17 | 北京工业大学 | Novel blood vessel support |
| CN106073957A (en) * | 2016-06-20 | 2016-11-09 | 常州乐奥医疗科技股份有限公司 | A kind of Novel weaved intravascular stent |
| CN108720972A (en) * | 2017-04-19 | 2018-11-02 | 北京航空航天大学 | A kind of self expandable for avoiding coronary artery from blocking intervention valve bracket |
| CN109223107A (en) * | 2018-11-09 | 2019-01-18 | 鼎科医疗技术（苏州）有限公司 | One kind taking pin device |
-
2019
- 2019-03-11 CN CN201910181781.1A patent/CN109771097A/en active Pending
Patent Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201001791Y (en) * | 2007-02-12 | 2008-01-09 | 孔祥清 | Stent for reducing left ventricular mitral back-flow and its conveying device |
| US20100256732A1 (en) * | 2008-10-16 | 2010-10-07 | Kyong-Min Shin | Wavily deformable stent and method for producing the same |
| CN101606869A (en) * | 2009-07-13 | 2009-12-23 | 成正辉 | Cerebral aneurysm endovascular plastic repair bracket and conveyer device thereof |
| CN101991477A (en) * | 2009-08-27 | 2011-03-30 | 微创医疗器械(上海)有限公司 | Vascular reconstructive support frame |
| CN202724037U (en) * | 2012-08-01 | 2013-02-13 | 吕文峰 | Support and conveying system thereof for treating arterial aneurysm |
| CN104736107A (en) * | 2012-10-25 | 2015-06-24 | W.L.戈尔及同仁股份有限公司 | Stent with varying cross-section |
| CN203885667U (en) * | 2014-06-06 | 2014-10-22 | 微创神通医疗科技（上海）有限公司 | Stent |
| CN204133642U (en) * | 2014-06-25 | 2015-02-04 | 北京奇伦天佑创业投资有限公司 | The support of overlay film frame and the implant system implanted respectively with overlay film thereof |
| CN205031392U (en) * | 2015-09-25 | 2016-02-17 | 北京工业大学 | Novel blood vessel support |
| CN105287051A (en) * | 2015-09-30 | 2016-02-03 | 复旦大学附属中山医院 | Artificial aortic valve ring system implanted through peripheral arterial approach |
| CN106073957A (en) * | 2016-06-20 | 2016-11-09 | 常州乐奥医疗科技股份有限公司 | A kind of Novel weaved intravascular stent |
| CN108720972A (en) * | 2017-04-19 | 2018-11-02 | 北京航空航天大学 | A kind of self expandable for avoiding coronary artery from blocking intervention valve bracket |
| CN109223107A (en) * | 2018-11-09 | 2019-01-18 | 鼎科医疗技术（苏州）有限公司 | One kind taking pin device |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111407466A (en) * | 2020-03-27 | 2020-07-14 | 山东大学齐鲁医院 | Implantable biological valve |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20230233318A1 (en) | Modular valve prosthesis with anchor stent and valve component | |
| JP6473682B2 (en) | Implantable device for treating heart valve regurgitation | |
| JP6560507B2 (en) | Device for implantation in the heart of a mammal | |
| EP3052053B1 (en) | Device for mitral valve regurgitation method | |
| CN105578991B (en) | It is equipped with valve leaflets heart valve support device | |
| CA2922123C (en) | Device and use for mitral valve regurgitation treatment | |
| JP2023099828A (en) | Information marker for heart prosthesis and method of using the same | |
| EP3043746B1 (en) | Vascular implant | |
| EP2600798B1 (en) | Two valve caval stent for functional replacement of incompetent tricuspid valve | |
| CN111447889A (en) | Adjustable prosthetic heart valve | |
| CN105520792A (en) | D-shaped invasive prosthetic heart valve | |
| CN203736349U (en) | Novel aorta valve stent | |
| CN103517688A (en) | Valve prosthesis for replacing an atrioventricular valve of the heart | |
| CN105726167A (en) | Involved artificial heart valve prosthesis | |
| WO2023155538A1 (en) | Anchoring devices of artificial heart valve and artificial heart valve system | |
| CN104799974A (en) | Involvement type prosthetic heart valve stent with barbs and preparation method thereof | |
| CN103598939A (en) | Safety improved pulmonary artery stent and pulmonary artery valve replacement device | |
| CN205434001U (en) | D shape intervention formula artificial heart valve | |
| CN209377809U (en) | A kind of heart valve prosthesis prosthese and its bracket | |
| CN103462728B (en) | A kind of aortic valve prosthesis's holder and its transport system through conduit implantation | |
| WO2019062366A1 (en) | Heart valve prosthesis | |
| CN205434002U (en) | Intervention formula artificial heart valve | |
| CN203379235U (en) | Pulmonary artery support and pulmonary artery valve replacement device with thereof | |
| WO2022262110A1 (en) | Implant delivery apparatus and implant delivery system | |
| CN109771097A (en) | Manpower intervention type aortic valve stent with the variation of radial support power |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190521 |