CN215684072U

CN215684072U - Metabolism device and biological metabolism system

Info

Publication number: CN215684072U
Application number: CN202120968119.3U
Authority: CN
Inventors: 饶秀茸; 李敬; 黄芷媚
Original assignee: Shenzhen Topbiotech Co ltd
Current assignee: Shenzhen Lingfu Topu Biotechnology Co ltd
Priority date: 2021-05-07
Filing date: 2021-05-07
Publication date: 2022-02-01
Anticipated expiration: 2031-05-07

Abstract

The utility model provides a metabolism device and a biological metabolism system, the biological metabolism system comprises an air supply device, a ventilation pipeline, a cage frame and a metabolism device, the cage frame is provided with a placement position at least used for installing the metabolism device, the metabolism device is communicated with the air supply device through the ventilation pipeline, the metabolism device comprises an accommodating box, a chassis, a metabolism cage, a water supply structure and a urine collection structure, the accommodating box comprises a box body and a cover body which is assembled with the box body in a covering mode, the chassis can be installed in the box body, the chassis is provided with an installation position at least used for installing the metabolism cage, the water supply structure is connected to the metabolism cage, the water supply structure is used for supplying water into the metabolism cage, the urine collection structure can be assembled on the chassis and is positioned below the metabolism cage, and the urine collection structure is communicated with the bottom of the metabolism cage. The metabolism device of this scheme can carry out the urine to many animals simultaneously and collect, and occupation space is little and collection efficiency is high, can make the relevant experimental items progress of animal urine detection more smooth.

Description

Metabolism device and biological metabolism system

Technical Field

The utility model belongs to the technical field of experimental equipment, and particularly relates to a metabolism device and a biological metabolism system.

Background

Some experimental projects for animals need to collect urine of animals, for example, experiments for nephrology department, in the related art, a metabolism cage is used for collecting urine of animals, however, the metabolism cage in the market is generally bulky, and only a small number of animals can be collected at a time, so that the occupied space is large, the collection efficiency is low, and the progress of the related experimental projects is easily influenced.

SUMMERY OF THE UTILITY MODEL

The technical problem to be solved by the utility model is to provide a metabolic device and a biological metabolic system, which can be used for simultaneously collecting urine of a plurality of animals, have small occupied space and high collection efficiency, and can make the development of experimental projects related to animal urine detection more smooth.

In order to solve the technical problems, the utility model provides a metabolism device which comprises an accommodating box, a chassis, a metabolism cage, a water supply structure and a urine collection structure, wherein the accommodating box comprises a box body and a cover body which is assembled with the box body in a covering mode, the chassis can be installed in the box body, the chassis is provided with an installation position which is at least used for installing the metabolism cage, the water supply structure is connected to the metabolism cage, the water supply structure is used for supplying water into the metabolism cage, the urine collection structure can be assembled on the chassis and located below the metabolism cage, and the urine collection structure is communicated with the bottom of the metabolism cage.

Furthermore, the urine collecting structure comprises urine receiving containers which correspond to the metabolism cages one to one, and the urine receiving containers are communicated with the corresponding metabolism cages through pipelines.

Further, the bottom of metabolism cage is for leaking hopper-shaped, metabolism cage is including installing in the filter screen of the bottom in the metabolism cage.

Furthermore, the chassis is provided with a caulking groove corresponding to the mounting position one by one, the caulking groove is matched with the urine receiving container, and the caulking groove is used for mounting the urine receiving container.

Furthermore, the chassis comprises a first mounting plate and a second mounting plate fixed on the first mounting plate, the second mounting plate and the first mounting plate are arranged at intervals, and the caulking groove is formed in the first mounting plate;

the installation position set up in the second mounting panel, the installation position is including seting up in the card hole of second mounting panel and set up in the first location structure of card hole department, the outside of metabolism cage set up with the second location structure that first location structure matches, the metabolism cage is set in the card is downthehole just the second location structure with when first location structure matches, the metabolism cage suspension corresponds connect the urine container top.

Further, the cover body is provided with a ventilation structure, and the ventilation structure is used for communicating the inside of the box body with the outside.

Further, the metabolism cage comprises an isolation cover positioned at the top, and the isolation cover is connected with a breathable membrane.

Furthermore, the water supply structure comprises water storage containers which correspond to the metabolism cages one to one, the water storage containers are fixed on the isolation covers of the corresponding metabolism cages, and the water storage containers are connected with water supply pipes extending into the metabolism cages.

Furthermore, the water supply structure comprises water storage containers and water supply pipes which are in one-to-one correspondence with the metabolism cages, the water storage containers are assembled on the cover body, the water supply pipes are connected to the isolation covers of the corresponding metabolism cages, the water supply pipes extend into the corresponding metabolism cages, and each water supply pipe is communicated with the water storage containers.

Further, a biological metabolism system is provided, which comprises an air supply device, a ventilation pipeline, a cage and the metabolism device, wherein the cage is at least used for installing the placement position of the metabolism device, and the metabolism device is communicated with the air supply device through the ventilation pipeline.

Compared with the prior art, the metabolism device and the biological metabolism system have the advantages that:

at least two metabolism cages can be installed to the chassis, and the animal that needs to collect the urine puts into the metabolism cage in, the bottom and the collection urine structure intercommunication of metabolism cage, and water supply installation is connected to the metabolism cage, and the metabolism cage assembly can wholly put into the box body behind the chassis and close through the lid, and water supply installation can provide the drinking water for the animal, and the urine that the animal discharged can flow into the collection urine structure from the bottom of metabolism cage to realize collection urine function. The metabolism device of this scheme can carry out the urine to many animals simultaneously and collect, and occupation space is little and collection efficiency is high, can make the relevant experimental items progress of animal urine detection more smooth.

Drawings

FIG. 1 is a schematic view showing the structural layout of a metabolism apparatus in an embodiment of the present invention;

FIG. 2 is a schematic diagram of one implementation of a metabolic cage of a metabolic device in an embodiment of the present invention;

FIG. 3 is a schematic top view of a metabolic cage for collecting mouse urine in a containment box;

FIG. 4 is a schematic illustration of the configuration of the caulking groove of the first mounting plate of the metabolism apparatus for collecting mouse urine.

In the drawings, each reference numeral denotes: 1. a box is accommodated; 2. a chassis; 3. a metabolism cage; 4. a water supply structure; 5. a urine collection structure; 11. a box body; 12. a cover body; 21. a first mounting plate; 22. a second mounting plate; 211. caulking grooves; 31. filtering with a screen; 32. an isolation cover; 33. and (3) a breathable film.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the utility model and are not intended to limit the utility model.

Example (b):

in this embodiment, the biological metabolism system includes the air feed device, air pipe, cage and metabolism device, the cage has the position of placing that is used for installing metabolism device at least dually, metabolism device passes through air pipe and air feed device intercommunication, wherein, combine fig. 1-2, metabolism device includes containing box 1, chassis 2, metabolism cage 3, water supply structure 4 and urine collection structure 5, containing box 1 includes box 11 and the lid 12 of closing the assembly with box 11, chassis 2 can install in box 11, chassis 2 has the position of installing metabolism cage 3 at least dually, water supply structure 4 is connected in metabolism cage 3, water supply structure 4 is used for supplying water in the metabolism cage 3, urine collection structure 5 can assemble in chassis 2 and be located metabolism cage 3 below, urine collection structure 5 communicates the bottom of metabolism cage 3.

Chassis 2 can install two at least metabolism cages 3, the animal that needs to collect the urine is put into metabolism cage 3 in, the bottom and the 5 intercommunications of collection urine structure of metabolism cage 3, metabolism cage 3 connects water supply installation, metabolism cage 3 assembly can wholly put into box body 11 after chassis 2 and close through lid 12 lid, water supply installation can provide the drinking water for the animal, the urine that the animal discharged can flow into collection urine structure 5 from the bottom of metabolism cage 3 to realize collection urine function. The metabolism device of this scheme can carry out the urine to many animals simultaneously and collect, and occupation space is little and collection efficiency is high, can make the relevant experimental items progress of animal urine detection more smooth.

In the present embodiment, the biological metabolism system may be an independent aeration cage system (IVC system: independent aerated cage Systems), in the related art, the independent aeration cage means a closed independent unit (cage or cage) into which clean air is fed to intensively discharge waste gas, in the related art, experimental animals such as mice are usually cultured by such experimental equipment, but the existing system cannot be used for animal urine collection, in the present scheme, the independent aeration cage system is modified to be used for animal urine collection, wherein the housing box 1 is equivalent to the independent aeration cage.

In this embodiment, the urine collecting structure 5 comprises urine receiving containers in one-to-one correspondence with the metabolism cages 3, and the urine receiving containers are communicated with the corresponding metabolism cages 3 through pipes. Specifically, the urine receiving container can be a urine receiving cup, the urine receiving cup can be made of a transparent material, scales used for measuring the volume of urine can be arranged on the cup body of the urine receiving cup, so that the urine discharge amount of the animal in the corresponding metabolism cage 3 can be conveniently read, the bottom of the metabolism cage 3 can be connected with a guide pipe, one end of the guide pipe extends into the corresponding urine receiving cup, and the urine discharged by the animal can flow into the urine receiving cup through the guide pipe. In some embodiments, the urine receptacle may also be a urine receiving bottle. In some embodiments, the urine collecting structure 5 may be an integral structure, for example, the urine collecting structure 5 may be a plate-shaped structure, and one side of the plate-shaped structure facing the metabolism cage 3 is provided with spaced grooves, which are opposite to the bottom of the metabolism cage 3, and the grooves correspond to urine receiving containers.

The bottom of the metabolism cage 3 is funnel-shaped, and the metabolism cage 3 comprises a filter screen 31 arranged at the bottom in the metabolism cage 3. Specifically, in the present embodiment, the cross section of the metabolism cage 3 is preferably rectangular, especially square, so as to maximize the utilization of the internal space of the containing box 1, therefore, the bottom of the metabolism cage 3 is in an inverted frustum shape, the filter screen 31 is also in an inverted frustum shape, and the filter screen 31 is matched with the bottom of the metabolism cage 3, therefore, after the filter screen 31 is installed in the metabolism cage 3, the metabolism cage 3 has a flat bottom for the movement of animals, and the filter screen 31 can filter urine, so as to prevent the foreign matters such as feces and hair of the animals from flowing into the urine collecting structure 5 along with the urine; in order to make the assembly between filter screen 31 and metabolism cage 3 more swift and stable, the inboard of metabolism cage 3 bottom can set up a plurality of direction arriss, each direction arris is around the central line interval arrangement of metabolism cage 3, the central line of direction arris and metabolism cage 3 is located the coplanar, the week side of filter screen 31 can set up the spacing groove that matches with direction arris one-to-one and each other, when assembling filter screen 31, the direction arris can inlay and lead filter screen 31 in the spacing groove, after the assembly is accomplished, direction arris and spacing groove gomphosis assembly, thereby guarantee filter screen 31 and metabolism cage 3's assembly stability. In some embodiments, the shape of the cross section of the metabolism cage 3 can be adapted, for example, the cross section of the metabolism cage 3 can be circular, regular pentagon, regular hexagon, etc., correspondingly, the bottom of the metabolism cage 3 is an inverted round table, a pentagonal table, a hexagonal table, etc., and the filter screen 31 is matched with the bottom of the metabolism cage 3.

The chassis 2 is provided with a caulking groove 211 (as shown in fig. 4) corresponding to the mounting position one by one, the caulking groove 211 is matched with the urine receiving container, and the caulking groove 211 is used for mounting the urine receiving container. In the present embodiment, the chassis 2 includes a first mounting plate 21 and a second mounting plate 22 fixed to the first mounting plate 21, the second mounting plate 22 and the first mounting plate 21 are disposed at an interval, and the caulking groove 211 is opened in the first mounting plate 21; the installation position sets up in second mounting panel 22, and the installation position sets up the second location structure that matches with first location structure including seting up in the card hole of second mounting panel 22 and setting up in the first location structure of card hole department, the outside setting of metabolism cage 3, and when metabolism cage 3 inlays to be arranged in the card hole and second location structure and first location structure match, metabolism cage 3 suspension is in the corresponding urine container top that connects.

Specifically, the first mounting plate 21 and the second mounting plate 22 can be fixedly connected by a connecting frame, the connecting frame is matched with the inside of the box body 11, the connecting frame is provided with handle structures extending from the bottom to the cover body 12, the handle structures are symmetrically arranged at two sides of the connecting frame, the movable metabolism cage 3 can be conveniently and quickly driven by the handle structure, the first mounting plate 21 and the second mounting plate 22 are arranged in parallel, the first mounting plate 21 is provided with a plurality of caulking grooves 211 at equal intervals, the urine receiving container is embedded in the caulking grooves 211, thereby ensuring the installation stability of the urine receiving container, in order to improve the assembly speed of the urine receiving container and the caulking groove 211, the bottom of the urine receiving container can be in a frustum shape, the side wall of the caulking groove 211 is an inclined plane, that is, the section of the insertion groove 211 near the opening is larger than the section of the insertion groove 211 far from the opening, so that the urine receptacle can be guided when being assembled to the insertion groove 211, and the installation is more convenient. The outer profile matching of card hole and metabolism cage 3, the card hole of second mounting panel 22 is just to corresponding caulking groove 211, first location structure can be including seting up in deviating from first mounting panel 21 side of second mounting panel 22 and surrounding the constant head tank outside the locating hole and extending and surrounding the location edge outside the constant head tank towards the direction of keeping away from first mounting panel 21 from second mounting panel 22, second location structure can be the ladder groove that sets up in the outside of metabolism cage 3, specifically be two parts about metabolism cage 3 divide into, the partial cross-section of higher authority is greater than the cross-section of part below, thereby form the ladder groove, when the assembly, the ladder groove and the constant head tank gomphosis of metabolism cage 3, and, the outside of the upper portion of location edge ring in metabolism cage 3, in order to prevent that metabolism cage 3 is crooked. In some embodiments, first location structure also can be from the inboard of card hole two at least spaced location arch of extending inwards, second location structure can be set up in the vertical mounting groove in the metabolism cage 3 outside, the bottom of mounting groove is the opening, mounting groove and the protruding one-to-one in location, when installation metabolism cage 3, it is protruding to aim at the location with the mounting groove, then with metabolism cage 3 insert card downthehole can, the protruding final butt that can of location is on the top of mounting groove to realize metabolism cage 3's fixed Assembly. The first positioning structure and the second positioning structure of the scheme can be matched with each other, so that the metabolism cage 3 is fixed on the second mounting plate 22, and the metabolism cage 3 is suspended at the top of the urine collection container.

The lid 12 is provided with a ventilation structure for communicating the inside of the case 11 with the outside. Specifically, ventilation structure is including seting up the blow vent in one side of lid 12 and seting up the life window at lid 12 top, and the blow vent passes through air pipe and air supply device intercommunication, and air supply device lets in fresh air to holding box 1 in to guarantee the smooth breathing of animal, the life window will hold the inside and external intercommunication of box 1, even if air supply device stops the air feed, also can guarantee holding box 1 and external circulation of air, support for the animal provides the life.

In this embodiment, the metabolism cage 3 includes an isolation cover 32 at the top, and a gas permeable membrane 33 is attached to the isolation cover 32. The isolation cover 32 can be connected with the cage body of the metabolism cage 3 in a buckling mode, the assembly and the disassembly in the buckling connection mode are more convenient and quicker, and in some embodiments, the isolation cover 32 and the cage body of the metabolism cage 3 can be assembled in a threaded connection mode. The ventilated membrane 33 that sets up on the isolation lid 32 can be so that metabolism cage 3 and outside intercommunication to guarantee that the breathing of animal is smooth and easy, and ventilated membrane 33 and isolation lid 32 can prevent that the animal from running out from metabolism cage 3, go on with the job stabilization of guaranteeing to collect the urine.

In the present embodiment, the water supply structure 4 may be arranged in different ways:

in a first arrangement, the water supply structure 4 may comprise water storage containers in one-to-one correspondence with the metabolism cages 3, the water storage containers being fixed to the isolation covers 32 of the corresponding metabolism cages 3, the water storage containers being connected to water supply pipes extending into the metabolism cages 3. Specifically, in this kind of mode of setting, water storage container can be the water-jug to, water-jug and isolation lid 32 both can set up to an organic whole structure and also can set up to the components of a whole that can function independently structure, and the water-jug is located ventilated membrane 33's next door, and when the components of a whole that can function independently set up, the one end of water-jug can set up to be connected with isolation lid 32 threaded connection or buckle, through the mode that sets up a water storage container respectively for each metabolism cage 3, can provide the water source for the animal effectively, guarantee the normal life activity of animal.

In a second arrangement, the water supply structure 4 may include a water storage container assembled to the cover 12 and a water supply pipe corresponding to the metabolism cage 3 one-to-one, the water supply pipe being connected to the isolation cover 32 corresponding to the metabolism cage 3 and extending into the corresponding metabolism cage 3, each water supply pipe being communicated with the water storage container. Specifically, in this arrangement, the water storage container may be integrated with the cover 12, that is, when the cover 12 is processed, the water storage container is formed in the cover 12 as a part of the cover 12; in some embodiments, the water storage container may also be configured to be connected to the cover 12 by a screw or a snap, so that the water storage container and the cover 12 can be easily and conveniently detached from the water supply. In this arrangement, the water storage container and each metabolism cage 3 can be communicated in various ways, for example, in some ways, water supply pipes facing the water storage container one by one can be arranged on the bottom side of the cover body 12, each water supply pipe is communicated with the water storage container, a yielding hole is arranged on the top of the isolation cover 32, and when the cover body 12 is assembled, one end of each water supply pipe extends into the metabolism cage 3 from the yielding hole, so as to supply water to the animals in the metabolism cage 3; in other modes, the delivery pipe can directly be fixed in isolation cover 32, and the one end of delivery pipe stretches into in the metabolism cage 3, the other end of delivery pipe is the pipeline interface, the bottom side of lid 12 can set up the water supply hose the same with metabolism cage 3 quantity, water supply hose intercommunication water storage container, the tip of water supply hose is the interface that matches with the delivery pipe, and, can set up the pot head that is used for sealed water supply hose, after confirming the metabolism cage 3 that needs to supply water, can open the pot head of the tip of a water supply hose back and this metabolism cage 3's delivery pipe connection, thereby realize the water supply in the metabolism cage 3, when need not supplying water, with water supply hose and delivery pipe separation and the sealed corresponding water supply hose end of pot head with the pot head.

It will be appreciated that the number, shape and size of the metabolism cages 3, etc. may be adapted according to the size of the IVC cage and the size of the animal from which urine is to be collected. For example, two, three, four, five, etc. metabolism cages 3 may be provided. In the scheme, a cage box with the size of 470 h 312 h 260mm is taken as an example, when the device is used for collecting urine of a mouse, three rows and five columns of fifteen metabolism cages 3 can be arranged by combining with a figure 3-4, the size of the metabolism cages 3 can be 80mm in length, 70mm in width and 100mm in height, a breathable film 33 is 0.22um in thickness, a urine receiving cup is 30mm in diameter, and an embedded groove 211 is 35mm in diameter; when the urine collecting cup is used for collecting urine of a rat, two rows and two columns of the total four metabolism cages 3 can be arranged, the size of each metabolism cage 3 can be 120mm long, 110mm wide and 100mm high, the thickness of the breathable film 33 is 0.22um, the diameter of the urine receiving cup is 50mm, and the diameter of the caulking groove 211 is 55 mm.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the utility model, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.

Claims

1. The utility model provides a metabolism device, its characterized in that, includes containing box (1), chassis (2), metabolism cage (3), water supply structure (4) and collection urine structure (5), containing box (1) including box body (11) and with box body (11) lid closes lid (12) of assembly, chassis (2) can install in box body (11), chassis (2) have at least two and are used for the installation position of metabolism cage (3), water supply structure (4) connect in metabolism cage (3), water supply structure (4) be used for to supply water in metabolism cage (3), collection urine structure (5) can assemble in chassis (2) just are located metabolism cage (3) below, collection urine structure (5) intercommunication the bottom of metabolism cage (3).

2. The metabolic device according to claim 1, characterized in that said urine collecting structure (5) comprises urine receiving containers in one-to-one correspondence with said metabolic cages (3), said urine receiving containers communicating with the corresponding metabolic cages (3) through pipes.

3. The metabolizing device according to claim 2, characterized in that the bottom of the metabolizing cage (3) is funnel-shaped, and the metabolizing cage (3) comprises a sieve (31) mounted at the bottom inside the metabolizing cage (3).

4. The metabolizing device according to claim 2, characterized in that the chassis (2) is provided with one-to-one corresponding caulking grooves (211) to the mounting positions, the caulking grooves (211) are matched with the urine receiving containers, and the caulking grooves (211) are used for mounting the urine receiving containers.

5. The metabolic device according to claim 4, characterized in that the chassis (2) comprises a first mounting plate (21) and a second mounting plate (22) fixed to the first mounting plate (21), the second mounting plate (22) and the first mounting plate (21) being arranged at a distance, the caulking groove (211) opening into the first mounting plate (21);

the installation position set up in second mounting panel (22), the installation position is including seting up in the card hole of second mounting panel (22) and set up in the first location structure of card hole department, the outside of metabolism cage (3) set up with the second location structure that first location structure matches, metabolism cage (3) are embedded in the card is downthehole just the second location structure with when first location structure matches, metabolism cage (3) suspension is in corresponding connect the urine container top.

6. The metabolic device according to any one of claims 1-5, characterized in that the cover (12) is provided with a venting structure for communicating the inside of the cartridge (11) with the outside.

7. The metabolic device according to claim 6, characterized in that said metabolic cage (3) comprises a top insulating cover (32), said insulating cover (32) being connected with a gas permeable membrane (33).

8. The metabolizing device according to claim 7, characterized in that the water supply structure (4) comprises water storage containers corresponding to the metabolizing cages (3) one to one, the water storage containers are fixed to the isolating covers (32) of the corresponding metabolizing cages (3), and the water storage containers are connected with water supply pipes extending into the metabolizing cages (3).

9. The metabolizing device according to claim 7, characterized in that the water supply structure (4) comprises a water storage container and water supply pipes corresponding to the metabolizing cages (3) one by one, the water storage container is assembled on the cover body (12), the water supply pipes are connected to the isolation covers (32) of the corresponding metabolizing cages (3), the water supply pipes extend into the corresponding metabolizing cages (3), and each water supply pipe is communicated with the water storage container.

10. A biological metabolism system comprising an air supply means, an air duct, a cage and a metabolism apparatus as claimed in any one of claims 1 to 9, the cage having a placement site for at least two purposes for mounting the metabolism apparatus, the metabolism apparatus being in communication with the air supply means through the air duct.