CN215480952U

CN215480952U - Nephropathy detection kit based on second generation sequencing platform

Info

Publication number: CN215480952U
Application number: CN202121981338.1U
Authority: CN
Inventors: 曹春燕; 孟艳艳; 李延杰; 江俊杰; 李智富
Original assignee: Qingdao Yanshun Biotechnology Co ltd
Current assignee: Qingdao Yanshun Biotechnology Co ltd
Priority date: 2021-08-23
Filing date: 2021-08-23
Publication date: 2022-01-11
Anticipated expiration: 2031-08-23

Abstract

The utility model relates to the technical field of medical instruments and discloses a nephropathy detection kit based on a second-generation sequencing platform. This nephropathy detect reagent box based on next generation sequencing platform, it places the seat to be equipped with through the inside at the box body, and the standing groove has been seted up on the upper portion of placing the seat, the bottom fixed mounting who places the seat has the cooling jacket, the inside fixed mounting of cooling jacket has heat exchange tube and refrigerating plant, be convenient for refrigerate the inside reagent bottle of standing groove through heat exchange tube and refrigerating plant, guarantee that the inside urine sample of reagent bottle deposits, make diagnosing that the urine sample can be timely, guarantee the accurate accuracy of testing result, the practicality of device has been improved.

Description

Nephropathy detection kit based on second generation sequencing platform

Technical Field

The utility model relates to the technical field of medical instruments, in particular to a nephropathy detection kit based on a second-generation sequencing platform.

Background

The kidney is an important organ that excretes water, metabolites and wastes to maintain the balance of body water, electrolytes and acid-base, and in addition, the kidney also makes some important physiologically active substances, such as renin and erythropoietin, etc., having important functions of regulating blood pressure, endocrine and hematopoiesis, and even the most sensitive examination method cannot detect early and slight damage of renal parenchyma due to its strong storage ability and being affected by individual differences, so the examination of renal function is of great significance for understanding the existence of renal diseases, the degree of diseases, selective treatment, understanding prognosis and research on renal diseases.

Along with the increase of human age, a series of structural changes have taken place for the kidney, for example glomerular vascular atherosclerosis increases, interstitial fibrosis aggravates, renal tubule atrophy and so on, kidney function gradually declines thereupon, clinical evaluation kidney needs to carry out sample detection, need use reagent pipe during the detection, present reagent pipe is the glass material mostly, cause the breakage of reagent pipe easily, and present kit does not all set up the mechanism that carries out the save to the urine, lead to the testing result inaccurate, reduced the practicality of device.

SUMMERY OF THE UTILITY MODEL

Aiming at the defects of the prior art, the utility model provides a nephropathy detection kit based on a second-generation sequencing platform, which has the advantages of good storage effect and convenience in detection and transportation, and solves the problems in the background technology.

The utility model provides the following technical scheme: the utility model provides a nephropathy detect reagent box based on next generation sequencing platform, includes the box body, the upper end of box body is equipped with the lid, the inside bottom fixed mounting of box body has the sponge base, the inside of sponge base is equipped with the glass test tube, the top movable mounting of sponge base has the seat of placing, the standing groove has been seted up to the upper end of placing the seat, the bottom fixed mounting who places the seat has the cooling jacket, the inside fixed mounting of cooling jacket has the heat exchange tube, one side fixed mounting of heat exchange tube has refrigerating plant, the inside movable mounting of standing groove has the reagent shell, the inside fixedly connected with spring of reagent shell, the bottom fixedly connected with end cap of spring, the below of end cap is equipped with reagent bottle, reagent bottle movable mounting is in the inside of reagent shell.

The tool box is characterized in that a tool rack is arranged inside the box cover, and a tool groove is fixedly arranged inside the tool rack.

Carefully selecting, the both sides of standing groove are equipped with logical groove, just the logical groove and the cooling jacket of standing groove communicate.

Carefully, the quantity of reagent shell and glass test tube is fifteen, and fifteen the reagent shell and the inside of glass test tube one-to-one setting at the box body.

Carefully selecting, the upper surface of placing the seat is equipped with the label, and label fixed mounting is under the standing groove.

Carefully selecting, the diameter value of the reagent shell is consistent with that of the placing groove, and the inner diameter value of the reagent shell is consistent with that of the reagent bottle.

Compared with the prior art, the utility model has the following beneficial effects:

1. this nephropathy detect reagent box based on next generation sequencing platform, it places the seat to be equipped with through the inside at the box body, and the standing groove has been seted up on the upper portion of placing the seat, the bottom fixed mounting who places the seat has the cooling jacket, the inside fixed mounting of cooling jacket has heat exchange tube and refrigerating plant, be convenient for refrigerate the inside reagent bottle of standing groove through heat exchange tube and refrigerating plant, guarantee that the inside urine sample of reagent bottle deposits, make diagnosing that the urine sample can be timely, guarantee the accurate accuracy of testing result, the practicality of device has been improved.

2. This nephropathy detect reagent box based on next generation sequencing platform, be equipped with the reagent shell through the outside at the reagent bottle, the inside of reagent shell is equipped with spring and end cap, the in-process that cup joints through reagent shell and reagent bottle is tightly detained the end cap at the upper end of reagent bottle, be convenient for seal the save to the inside urine sample of reagent bottle, avoid oozing and the leakage of urine sample, be convenient for shift and save the detection sample, and the top of box body is equipped with the tool holder, the inside of tool holder is equipped with the tool groove, be convenient for place the instrument of kit testing in-process through tool holder and tool groove, the use of the kit of being convenient for.

Drawings

FIG. 1 is a schematic structural view of the present invention;

fig. 2 is an exploded view of the seat of the present invention;

FIG. 3 is a cross-sectional view of the cartridge of the present invention;

FIG. 4 is a sectional view of a reagent bottle according to the present invention.

In the figure: 1. a box body; 2. a box cover; 3. a tool holder; 4. a tool slot; 5. a placing seat; 6. a placement groove; 7. a reagent housing; 8. a reagent bottle; 9. a plug; 10. a spring; 11. a cooling jacket; 12. a heat exchange pipe; 13. a refrigeration device; 14. a sponge base; 15. glass test tubes.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-3, a kidney disease detection kit based on a second generation sequencing platform comprises a box body 1, a box cover 2 is arranged at the upper end of the box body 1, a tool rack 3 is arranged inside the box cover 2, a tool groove 4 is fixedly arranged inside the tool rack 3, the tool rack 3 and the tool groove 4 are arranged to facilitate independent placement of some cotton swab and other instruments in the using process of the kit, shaking and damage during moving are avoided, a sponge base 14 is fixedly arranged at the bottom end inside the box body 1, a glass test tube 15 is arranged inside the sponge base 14, a placing seat 5 is movably arranged above the sponge base 14, a label is arranged on the upper surface of the placing seat 5 and is fixedly arranged under the placing groove 6, the label on the placing groove 6 facilitates timely labeling of a reagent shell 7 inside the placing groove 6, and errors and omissions are avoided, the accuracy of detection data is ensured, the upper end of the placing seat 5 is provided with the placing groove 6, two sides of the placing groove 6 are provided with through grooves, the through grooves of the placing groove 6 are communicated with the cooling cover 11, the through grooves of the placing groove 6 circulate cold air in the cooling cover 11, a reagent shell 7 in the placing seat 5 is conveniently refrigerated, a urine sample in the reagent shell 7 is conveniently stored, the accuracy of the sample is conveniently ensured, the bottom end of the placing seat 5 is fixedly provided with the cooling cover 11, the inside of the cooling cover 11 is fixedly provided with the heat exchange tube 12, one side of the heat exchange tube 12 is fixedly provided with the refrigerating device 13, the inside of the placing groove 6 is movably provided with the reagent shell 7, the diameter value of the reagent shell 7 is consistent with that of the placing groove 6, the inside of the reagent shell 7 is consistent with that of the reagent bottle 8, the reagent shell 7 is placed in the placing groove 6, the reagent bottle 8 and the urine sample in the reagent bottle 8 inside of the reagent shell 7 are stored, avoid appearing leaking and polluting, the inside fixedly connected with spring 10 of reagent shell 7, the bottom fixedly connected with end cap 9 of spring 10, the below of end cap 9 is equipped with reagent bottle 8, and reagent bottle 8 movable mounting is in the inside of reagent shell 7.

Referring to fig. 2, the number of the reagent shells 7 and the number of the glass test tubes 15 are fifteen, and the fifteen reagent shells 7 and the fifteen glass test tubes 15 are correspondingly arranged inside the box body 1 one by one, so that the number of the reagent shells 7 and the number of the glass test tubes 15 are consistent, errors are avoided, and the number of detections inside the kit is increased.

The working principle is as follows: during the use, expand the device, take out tool holder 3, will place seat 5 and take out, and take out top 6 inboard reagent casings 7 of standing groove, take out glass test tube 15 at last, orderly the placing on the mesa in proper order, and pair the use one by one, the urine sample that will detect the sample is put in the inside of reagent bottle 8, and use the reagent in glass test tube 15, press reagent bottle 8 in the inside of reagent casing 7 afterwards, carry out open-ended shutoff through end cap 9, and fix reagent casing 7 and reagent bottle 8 whole inside of placing groove 6, later with glass test tube 15, place seat 5 and tool holder 3 in proper order the inside of placing at box body 1, seal lid 2, can.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Meanwhile, in the drawings of the utility model, the filling pattern is only used for distinguishing the layers and is not limited at all.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a nephropathy detect reagent box based on next generation sequencing platform, includes box body (1), its characterized in that: the reagent box is characterized in that a box cover (2) is arranged at the upper end of the box body (1), a sponge base (14) is fixedly arranged at the bottom end inside the box body (1), a glass test tube (15) is arranged inside the sponge base (14), a placing seat (5) is movably arranged above the sponge base (14), a placing groove (6) is formed in the upper end of the placing seat (5), a cooling cover (11) is fixedly arranged at the bottom end of the placing seat (5), a heat exchange tube (12) is fixedly arranged inside the cooling cover (11), a refrigerating device (13) is fixedly arranged on one side of the heat exchange tube (12), a reagent shell (7) is movably arranged inside the placing groove (6), a spring (10) is fixedly connected inside the reagent shell (7), a plug (9) is fixedly connected at the bottom end of the spring (10), and a reagent bottle (8) is arranged below the plug (9), the reagent bottle (8) is movably arranged in the reagent shell (7).

2. The nephropathy detection kit based on the next generation sequencing platform as claimed in claim 1, wherein: the tool holder is characterized in that a tool holder (3) is arranged inside the box cover (2), and a tool groove (4) is fixedly arranged inside the tool holder (3).

3. The nephropathy detection kit based on the next generation sequencing platform as claimed in claim 1, wherein: through grooves are formed in two sides of the placing groove (6), and the through grooves of the placing groove (6) are communicated with the cooling cover (11).

4. The nephropathy detection kit based on the next generation sequencing platform as claimed in claim 1, wherein: the number of the reagent shells (7) and the number of the glass test tubes (15) are fifteen, and the reagent shells (7) and the glass test tubes (15) are correspondingly arranged in the box body (1) one by one.

5. The nephropathy detection kit based on the next generation sequencing platform as claimed in claim 1, wherein: the upper surface of the placing seat (5) is provided with a label, and the label is fixedly arranged under the placing groove (6).

6. The nephropathy detection kit based on the next-generation sequencing platform as claimed in claim 4, wherein: the diameter value of the reagent shell (7) is consistent with that of the placing groove (6), and the inner diameter value of the reagent shell (7) is consistent with that of the reagent bottle (8).