CN215448991U - Fungus immunomagnetic bead purification and dyeing integrated device - Google Patents
Fungus immunomagnetic bead purification and dyeing integrated device Download PDFInfo
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- CN215448991U CN215448991U CN202121432465.6U CN202121432465U CN215448991U CN 215448991 U CN215448991 U CN 215448991U CN 202121432465 U CN202121432465 U CN 202121432465U CN 215448991 U CN215448991 U CN 215448991U
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Abstract
The utility model discloses a fungus immunomagnetic bead purification and dyeing integrated device, which comprises a shell, wherein a first electric push rod is vertically arranged at the top of the inner side of the shell, a second electric push rod and a base are respectively arranged at the bottom of the inner side of the shell, a T-shaped groove is formed in the upper surface of the base, a moving plate is slidably arranged in the T-shaped groove, one end of the second electric push rod is fixedly connected to one end of the moving plate, a rectangular groove is formed in the top of the moving plate, and a four-hole plate is arranged in the rectangular groove; the utility model completes detection in the four-hole plate by adopting the first electric push rod, the second electric push rod, the base and the movable plate to match with the magnetic rods, thereby not only reducing the detection period, but also avoiding the generation of aerosol, and the detection is carried out in the shell, the interference factors are less, and the detection is not in direct contact with people, thereby avoiding the risk of being infected, and when the temperature in the shell is lower than the required detection temperature, the temperature in the shell can be raised through the electric heating wire, thereby ensuring the normal operation of the detection.
Description
Technical Field
The utility model relates to the technical field of detection devices, in particular to a fungus immunomagnetic bead purification and dyeing integrated device.
Background
The microbial examination of fungal infection has important value for the diagnosis of mycosis, the traditional method is to use a microscope to observe fungal hypha and spore morphology for diagnosis, the current clinical diagnosis of fungal infection mostly depends on direct smear microscopy, the spore and hypha morphology is searched under a common microscope as the evidence of fungal infection, but the defects of the conventional microscopy mainly lie in that: because of direct microscopic examination, smear sampling amount is less, detection period is long, omission factor is high, aerosol is easy to generate, a laboratory is polluted, interference factors are more, false negative or false positive results are easy to occur, and therefore the fungus immunomagnetic bead purification and dyeing integrated device is provided.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide an integrated device for purifying and dyeing fungal immunomagnetic beads, so as to solve the problems in the background technology.
In order to achieve the purpose, the utility model provides the following technical scheme: a fungus immunomagnetic bead purification and dyeing integrated device comprises a shell, wherein a first electric push rod is vertically installed at the top of the inner side of the shell, a circular groove for fixing a magnetic rod is formed in the tail end of the first electric push rod, and a compression bolt is installed on the outer wall of the tail end of the first electric push rod;
the movable plate is characterized in that a second electric push rod and a base are respectively installed at the bottom of the inner side of the shell, a T-shaped groove is formed in the upper surface of the base, a movable plate is installed inside the T-shaped groove in a sliding mode, one end of the second electric push rod is fixedly connected to one end of the movable plate, a rectangular groove is formed in the top of the movable plate, and a four-hole plate is placed inside the rectangular groove.
Through adopting above-mentioned technical scheme, put into a hole in proper order in four downtheholes of four orifice plates earlier during the use: cell lysate (5% KOH)0.6ml, well two: fungal immunomagnetic beads 0.6ml, well three: fungal immunofluorescent chromogenic reagent 0.6ml, well four: purified water 100ul, then will detect the sample and place No. one downthehole schizolysis, pull up the door plant through the handle, four pore plates that will hold good medicine are put into rectangle recess inside, then close the door plant, place the hole site that needs the operation in under the bar magnet through adjusting second electric putter, then drive the bar magnet up-and-down motion through adjusting first electric putter, progressively accomplish detection operation, the inside temperature of casing is looked over to the accessible thermometer during detection, accessible heating wire heating when the temperature is low excessively.
Preferably, one side of the housing is provided with a glass plate structure.
By adopting the technical scheme, the reaction state during detection is convenient to observe.
Preferably, the side of the shell is provided with a sliding chute, a door plate is inserted in the sliding chute in a sliding mode, and a handle is installed on the side of the door plate.
Through adopting above-mentioned technical scheme, through the installation of the convenient movable plate of pull door plant and taking of four orifice plates.
Preferably, two sides of the rectangular groove are provided with notches.
Through adopting above-mentioned technical scheme, be convenient for four orifice plates through the breach and take out in the rectangle recess.
Preferably, a T-shaped clamping seat is integrally formed at the bottom of the moving plate, and the T-shaped clamping seat is slidably clamped inside the T-shaped groove.
Through adopting above-mentioned technical scheme for the movable plate can not drop from the base.
Preferably, four holes with the depth of 1.2mm are equidistantly formed in the surface of the four-hole plate.
By adopting the technical scheme, the detection requirement is met, and meanwhile, the observation is more convenient.
Preferably, the interlayer of the shell is filled with a heat insulation cotton layer.
Through adopting above-mentioned technical scheme for the inside difficult heat exchange that carries out with the external world of casing.
Preferably, the inner wall of the shell is provided with the heating wire in a surrounding manner, and the inner wall of the shell is provided with the thermometer.
Through adopting above-mentioned technical scheme, observe the inside back that is less than the detection requirement temperature of casing through the thermometer, the accessible heating wire heats.
Compared with the prior art, the utility model has the beneficial effects that:
according to the utility model, the detection is completed in the four-hole plate by adopting the first electric push rod, the second electric push rod, the base and the movable plate to match with the magnetic rods, so that the detection period is shortened, the generation of aerosol is avoided, the detection is carried out in the shell, interference factors are less, the detection is not in direct contact with people, the risk of infection is avoided, when the temperature in the shell is lower than the required detection temperature, the temperature in the shell can be increased through the electric heating wire, the normal operation of the detection is ensured, and the problem of false negative or false positive results is avoided.
Drawings
FIG. 1 is a cross-sectional view of the present invention;
FIG. 2 is a schematic structural view of a door panel according to the present invention;
FIG. 3 is a schematic structural diagram of a base according to the present invention;
fig. 4 is a schematic structural diagram of the moving plate of the present invention.
In the figure: 1. a housing; 101. a chute; 102. a door panel; 1021. a handle; 201. a second electric push rod; 202. a base; 2021. a T-shaped slot; 203. moving the plate; 2031. a T-shaped card seat; 2032. a rectangular groove; 2033. a notch; 3. a first electric push rod; 301. a circular groove; 302. a hold-down bolt; 4. a magnetic bar; 5. four orifice plates; 6. a thermometer.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-4, the present invention provides a technical solution:
the utility model provides a fungi immunomagnetic bead purification and dyeing integral type device, which comprises a housing 1, one side of casing 1 sets up to the glass plate structure, be convenient for observe the reaction state when examining, spout 101 has been seted up to the side of casing 1, the inside slip grafting of spout 101 has door plant 102, handle 1021 is installed to the side of door plant 102, through the installation of the convenient movable plate 203 of pull door plant 102 and the taking and putting of four orifice plates 5, the intermediate layer of casing 1 all fills the cotton layer that keeps warm, make the inside difficult heat exchange with the external world of casing 1, the inner wall of casing 1 encircles and installs the heating wire, thermometer 6 is installed to the inner wall of casing 1, after observing that the inside of casing 1 is less than the required temperature of detection through thermometer 6, can heat through the heating wire;
a first electric push rod 3 is vertically arranged at the top of the inner side of the shell 1, a circular groove 301 for fixing the magnetic rod 4 is formed in the tail end of the first electric push rod 3, and a compression bolt 302 is arranged on the outer wall of the tail end of the first electric push rod 3;
the bottom of the inner side of the housing 1 is respectively provided with a second electric push rod 201 and a base 202, the upper surface of the base 202 is provided with a T-shaped groove 2021, a moving plate 203 is slidably mounted in the T-shaped groove 2021, the bottom of the moving plate 203 is integrally formed with a T-shaped cassette 2031, and the T-shaped cassette 2031 is slidably clamped in the T-shaped groove 2021, so that the moving plate 203 cannot fall off the base 202;
one end of the second electric push rod 201 is fixedly connected to one end of the moving plate 203, a rectangular groove 2032 is formed in the top of the moving plate 203, four orifice plates 5 are placed inside the rectangular groove 2032, notches 2033 are formed in two sides of the rectangular groove 2032, and the four orifice plates 5 can be conveniently taken out of the rectangular groove 2032 through the notches 2033;
wherein, four holes that the degree of depth is 1.2mm are seted up to four orifice plates 5's surperficial equidistance, when satisfying the detection requirement, are convenient for more observe.
The working principle is as follows: when in use, the first hole is firstly sequentially arranged in the four holes of the four-hole plate: cell lysate (5% KOH)0.6ml, well two: fungal immunomagnetic beads 0.6ml, well three: fungal immunofluorescent chromogenic reagent 0.6ml, well four: purified water 100ul, then place the detection specimen in downthehole schizolysis No. one, pull up door plant 102 through handle 1021, the inside of rectangle recess 2032 is put into to four pore boards 5 that will hold good medicine, then close door plant 102, place the hole site that needs the operation in magnetic rod 4 through adjusting second electric putter 201 under, then drive the up-and-down motion of magnetic rod 4 through adjusting first electric putter 3, gradually accomplish detection operation, the inside temperature of casing 1 is looked over to accessible thermometer 6 during the detection, accessible heating wire heating when the temperature is low excessively.
In summary, the first electric push rod 3, the second electric push rod 201, the base 202, the moving plate 203 and the magnetic rods 4 are adopted to complete detection in the four-hole plate 5, so that the detection period is shortened, aerosol is avoided, the detection is performed in the shell 1 during detection, interference factors are few, the detection is not in direct contact with people, the risk of infection is avoided, and when the temperature in the shell 1 is lower than the required detection temperature, the temperature inside the shell can be raised through the electric heating wires, and the normal operation of the detection is ensured.
The parts not involved in the present invention are the same as or can be implemented by the prior art. Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. The utility model provides a fungi immunomagnetic bead purification and dyeing integral type device, includes casing (1), its characterized in that:
a first electric push rod (3) is vertically installed at the top of the inner side of the shell (1), a circular groove (301) used for fixing the magnetic rod (4) is formed in the tail end of the first electric push rod (3), and a compression bolt (302) is installed on the outer wall of the tail end of the first electric push rod (3);
second electric putter (201) and base (202) are installed respectively to the inboard bottom of casing (1), T-slot (2021) have been seted up to the upper surface of base (202), inside slidable mounting in T-slot (2021) has movable plate (203), the one end fixed connection of second electric putter (201) is in the one end of movable plate (203), rectangular groove (2032) have been seted up at the top of movable plate (203), four orifice plates (5) have been placed to the inside of rectangular groove (2032).
2. The integrated apparatus for purification and staining of fungal immunomagnetic beads according to claim 1, wherein: one side of the shell (1) is provided with a glass plate structure.
3. The integrated apparatus for purification and staining of fungal immunomagnetic beads according to claim 1, wherein: a sliding groove (101) is formed in the side face of the shell (1), a door plate (102) is inserted in the sliding groove (101) in a sliding mode, and a handle (1021) is installed on the side face of the door plate (102).
4. The integrated apparatus for purification and staining of fungal immunomagnetic beads according to claim 1, wherein: notches (2033) are formed in two sides of the rectangular groove (2032).
5. The integrated apparatus for purification and staining of fungal immunomagnetic beads according to claim 1, wherein: the bottom of the moving plate (203) is integrally formed with a T-shaped clamping seat (2031), and the T-shaped clamping seat (2031) is clamped in the T-shaped groove (2021) in a sliding manner.
6. The integrated apparatus for purification and staining of fungal immunomagnetic beads according to claim 1, wherein: four holes with the depth of 1.2mm are equidistantly arranged on the surface of the four-hole plate (5).
7. The integrated apparatus for purification and staining of fungal immunomagnetic beads according to claim 1, wherein: the interlayer of the shell (1) is filled with a heat insulation cotton layer.
8. The integrated apparatus for purification and staining of fungal immunomagnetic beads according to claim 1, wherein: the inner wall of the shell (1) is provided with an electric heating wire in a surrounding mode, and the inner wall of the shell (1) is provided with a thermometer (6).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121432465.6U CN215448991U (en) | 2021-06-28 | 2021-06-28 | Fungus immunomagnetic bead purification and dyeing integrated device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121432465.6U CN215448991U (en) | 2021-06-28 | 2021-06-28 | Fungus immunomagnetic bead purification and dyeing integrated device |
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| CN215448991U true CN215448991U (en) | 2022-01-07 |
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| CN202121432465.6U Active CN215448991U (en) | 2021-06-28 | 2021-06-28 | Fungus immunomagnetic bead purification and dyeing integrated device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116359118A (en) * | 2023-05-31 | 2023-06-30 | 东营市特种设备检验研究院 | Oil gas storage and transportation container detection device |
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2021
- 2021-06-28 CN CN202121432465.6U patent/CN215448991U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116359118A (en) * | 2023-05-31 | 2023-06-30 | 东营市特种设备检验研究院 | Oil gas storage and transportation container detection device |
| CN116359118B (en) * | 2023-05-31 | 2023-08-04 | 东营市特种设备检验研究院 | Oil gas storage and transportation container detection device |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220424 Address after: 225300 Taizhou pharmaceutical hi tech Industrial Development Zone, Jiangsu Province Patentee after: JIANGSU NUOGE BIOTECHNOLOGY CO.,LTD. Address before: 210007 room 603, building 2, No. 50, Shiyang Road, Qinhuai District, Nanjing, Jiangsu Province Patentee before: Xian Tao |
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| TR01 | Transfer of patent right |