CN215362454U

CN215362454U - Antinuclear antibody spectrum detection kit convenient to operate

Info

Publication number: CN215362454U
Application number: CN202121010341.9U
Authority: CN
Inventors: 谢先洲; 鲁翌; 易丕冽
Original assignee: Wuhan Thalys Biological Technology Co ltd
Current assignee: Wuhan Thalys Biological Technology Co ltd
Priority date: 2021-05-12
Filing date: 2021-05-12
Publication date: 2021-12-31
Anticipated expiration: 2031-05-12

Abstract

The utility model discloses an antinuclear antibody spectrum detection kit convenient to operate, which comprises a main box body, wherein the top of the main box body is provided with a splicing box body, the bottom surface of the splicing box body is provided with a splicing groove, the joint of the top surface of the main box body and the splicing groove is provided with a splicing bulge, the splicing bulge extends into the splicing groove to be clamped and connected, the inner side of the splicing box body is integrally provided with a positioning plate, the splicing box body which can be flexibly installed and detached through clamping is additionally arranged on the main box body, the positioning plate and the positioning hole are designed on the splicing box body, and a reagent tube with an extension ring is simultaneously designed, so that the reagent tube can be fixed, and when chemical changes in the reagent tube need to be observed, the splicing box body can be lifted up, the reagent tube can still be hung in the positioning hole through the extension ring, the bottom end of the reagent tube is exposed, and an experimenter can conveniently observe the changes in a plurality of reagent tubes simultaneously, the operation is more convenient and faster.

Description

Antinuclear antibody spectrum detection kit convenient to operate

Technical Field

The utility model belongs to the technical field of kits, and particularly relates to an antinuclear antibody spectrum detection kit convenient to operate.

Background

The detection method of clinical antinuclear antibody (ANA) is mainly immunoblotting or banding enzyme immunoassay, and the technical principle is that after the membrane strip coated with antigen is treated by using blocking liquor, the non-specific site on the membrane strip is blocked so as to prevent the occurrence of non-specific reaction, if the sample is positive, the specific IgG is combined with correspondent antigen, after the sample is washed, the enzyme conjugate is added, and incubated, after the sample is washed, the developing liquor is added, and the developing result of the membrane strip can be observed. In order to ensure the stability of reagents in kits generally produced in the industry, the produced sealant is in a dry powder state, the enzyme conjugate is a concentrated liquid, and the reagent after secondary treatment needs to be used after secondary treatment; the existing blocking agent is in a ready-to-use type, the main components of the blocking agent are PBS buffer solution, high-purity protein, Tween-20, polyethylene glycol, preservative and the like, the technical principle is that the reagent is guaranteed to be in a ready-to-use type without influencing the action mechanism of the blocking solution in a kit, and secondary treatment is not needed, so that the core of the utility model is to improve the stability of the reagent. The high-purity protein acts on the non-specific binding site in the closed membrane strip, and the polyethylene glycol and the Tween-20 can ensure the activity of the protein and the stability of the molecular structure of the protein, so that the protein can be stored in the solution for a long time; at present, antinuclear antibody spectrum detects and uses kit generally all is fixed structure, and the kit is placed in the reagent box at the in-process reagent pipe that uses, reagent socle bottom and desktop or laboratory bench contact, because the laboratory bench is for the anticorrosion, generally all be some anticorrosive metal material, it is too high or low excessively to probably appear the laboratory bench face temperature under special weather, probably influence the intraductal chemical reaction of reagent, thereby influence the test result, in addition after present reagent pipe is placed in the reagent box, the reagent box covers the reagent pipe, be not convenient for observe the chemical change of reagent, if want to observe can only one take to see, it is very inconvenient.

SUMMERY OF THE UTILITY MODEL

The present invention aims to provide an antinuclear antibody spectrum detection kit which is convenient to operate, so as to solve the problems in the background technology.

In order to achieve the purpose, the utility model provides the following technical scheme: an antinuclear antibody spectrum detection kit convenient to operate comprises a main box body, wherein a splicing box body is arranged at the top of the main box body, splicing grooves are formed in the bottom surface of the splicing box body, splicing protrusions are arranged at the joints of the top surface of the main box body and the splicing grooves, the splicing protrusions extend into the splicing grooves and are connected in a clamping manner, a positioning plate is integrally arranged on the inner side of the splicing box body, a plurality of positioning holes are formed in the top surface of the positioning plate at equal intervals, reagent tubes are placed inside the positioning holes, a constant-temperature base plate is arranged at the bottom of the main box body, an installation sliding groove is formed at the joint of the lower end of the inner side surface of the main box body and the constant-temperature base plate, one end of the installation sliding groove penetrates through one side surface of the main box body and is communicated with the outside, one side surface of the constant-temperature base plate extends to the opening position of the installation sliding groove, and a connecting plate is arranged on one side surface of the constant-temperature base plate relative to the outer side of the main box body, be provided with the card hole on the connecting plate, the opening edge of installation spout is provided with the plastics buckle, the plastics buckle aligns with the card hole, and the plastics buckle passes card hole block and connects, the bottom of reagent pipe extends to in the main box body, and the bottom and the laminating of constant temperature backing plate of reagent pipe, the top edge of reagent pipe is provided with the extension ring, the laminating of top opening edge of extension ring and locating hole.

Preferably, the extension ring and the reagent tube are of an integrated structure, and the diameter of the extension ring is 5mm larger than that of the positioning hole.

Preferably, the splicing groove is of a rectangular annular structure, and the size and the shape of the splicing groove are consistent with those of the splicing bulge.

Preferably, the end of the plastic buckle is a hook-shaped structure, and an inclined plane inclined by forty-five degrees is arranged on the outer side of the hook-shaped structure.

Preferably, the lower floor of constant temperature backing plate is provided with the rock wool layer, the upper strata of constant temperature backing plate is provided with the rubber layer.

Compared with the prior art, the utility model has the beneficial effects that: according to the utility model, the splicing box body which can be flexibly installed and disassembled through clamping is additionally arranged on the main box body, the positioning plate and the positioning hole are designed on the splicing box body, and the reagent tube with the extension ring is designed at the same time, so that the reagent tube can be fixed, and when chemical changes in the reagent tube need to be observed, the splicing box body can be lifted up, the reagent tube can still be hung in the positioning hole through the extension ring, the bottom end of the reagent tube is exposed, an experimenter can conveniently observe changes in a plurality of reagent tubes at the same time, and the operation is more convenient and rapid;

the constant temperature base plate which can be flexibly installed and detached is additionally arranged at the bottom of the main box body, so that the bottom of the reagent tube is in contact with the constant temperature base plate, the condition that the bottom of the reagent tube is in contact with an experiment table top with large temperature difference after the traditional reagent tube is placed in the reagent box is avoided, the condition that an experiment has errors is avoided, and the constant temperature base plate can be flexibly installed and detached and is convenient to replace and clean.

Drawings

FIG. 1 is a schematic front view of the present invention;

FIG. 2 is a schematic top view of the present invention;

FIG. 3 is a side cross-sectional structural view of the present invention;

FIG. 4 is a front sectional structural view of the main case of the present invention;

FIG. 5 is an enlarged schematic view of the structure at A of the present invention;

in the figure: 1. a main box body; 2. splicing the box bodies; 3. a connecting plate; 4. positioning a plate; 5. positioning holes; 6. a reagent tube; 7. a constant temperature base plate; 8. installing a chute; 9. splicing grooves; 10. splicing the bulges; 11. a clamping hole; 12. and (6) plastic buckles.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1 to 5, the present invention provides a technical solution: a nuclear-resistant antibody spectrum detection kit convenient to operate comprises a main box body 1, a splicing box body 2 is arranged at the top of the main box body 1, a splicing groove 9 is formed in the bottom surface of the splicing box body 2, splicing protrusions 10 are arranged at the joint of the top surface of the main box body 1 and the splicing groove 9, the splicing protrusions 10 extend into the splicing groove 9 to be connected in a clamping manner, in order to facilitate lifting of the splicing box body 2 and observation of chemical changes of a reagent tube 6 inside the splicing box body 2, a positioning plate 4 is integrally arranged on the inner side of the splicing box body 2, a plurality of positioning holes 5 are formed in the top surface of the positioning plate 4 at equal intervals to facilitate fixed placement of the reagent tube 6, the reagent tube 6 is placed inside the positioning holes 5, a constant-temperature base plate 7 is arranged at the bottom of the main box body 1, an installation chute 8 is arranged at the joint of the lower end of the inner side surface of the main box body 1 and the constant-temperature base plate 7, and one end of the installation chute 8 penetrates through one side surface of the main box body 1 and is communicated with the outside, one side surface of the constant temperature cushion plate 7 extends to the opening position of the mounting chute 8, a connecting plate 3 is arranged on one side surface of the constant temperature cushion plate 7 opposite to the outer side of the main box body 1, a clamping hole 11 is arranged on the connecting plate 3, a plastic buckle 12 is arranged on the opening edge of the mounting chute 8, the plastic buckle 12 is aligned with the clamping hole 11, and the plastic buckle 12 passes through the clamping hole 11 to be clamped and connected, in order to facilitate the fixing and the dismounting of the constant temperature cushion plate 7, the bottom of the reagent tube 6 extends into the main box body 1, and the bottom of the reagent tube 6 is jointed with the constant temperature cushion plate 7, in order to avoid reagent pipe 6 and laboratory bench direct contact's the condition, reduce the influence of difference in temperature to reagent reaction, the top edge of reagent pipe 6 is provided with the extension ring, extends ring and the laminating of the open-top edge of locating hole 5, and the condition that reagent pipe 6 drops from the locating hole takes place after in order to prevent to carry the concatenation box body 2.

In this embodiment, preferably, the extension ring and the reagent tube 6 are of an integral structure, and the diameter of the extension ring is 5mm larger than that of the positioning hole 5, so as to ensure that the reagent tube 6 is firmly clamped in the positioning hole 5.

In this embodiment, preferably, the splicing groove 9 is a rectangular ring structure, and the size and shape of the splicing groove 9 are consistent with the size and shape of the splicing protrusion 10, so as to ensure that the clamping installation is stable.

In this embodiment, preferably, the end of the plastic buckle 12 is a hook-shaped structure, and an inclined surface inclined by forty-five degrees is disposed on the outer side of the hook-shaped structure, so as to facilitate the plastic buckle 12 to be clamped into the hole 11.

In this embodiment, it is preferred, the lower floor of constant temperature backing plate 7 is provided with the rock wool layer, and on the temperature of preventing the laboratory bench transmitted the reagent pipe, the upper strata of constant temperature backing plate 7 was provided with the rubber layer, in order to reduce 6 impact forces of reagent pipe, avoided 6 pipe damages of reagent.

The working principle and the using process of the utility model are as follows: when the utility model is used, a plurality of reagent tubes 6 are placed in the positioning holes 5, so that the bottoms of the reagent tubes 6 are jointed with the constant temperature backing plate 7, so that the reagent tube 6 can not contact with the experiment table, the temperature of the experiment table can not be transferred to the reagent tube 6, thereby ensuring the temperature of the reagent to be constant, the extension ring at the top edge of the reagent tube 6 is jointed at the top opening edge of the positioning hole 5, then the experimental reagent is dropped in turn, when the chemical change in the reagent tube 6 needs to be observed, the splicing box body 2 can be lifted directly to separate the splicing groove 9 from the splicing bulge 10, thereby the splicing box body 2 is separated from the main box body 1 and lifted, the reagent tube 6 is still clamped in the positioning hole 5 through the extension ring, the bottom ends of the reagent tubes are all exposed out of the bottom of the splicing box body 2, the chemical change of the reagents in the reagent tubes 6 can be directly observed, and the operation is more convenient.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides an antinuclear antibody spectrum detection kit convenient to operation, includes main box body (1), its characterized in that: the top of the main box body (1) is provided with a splicing box body (2), the bottom surface of the splicing box body (2) is provided with a splicing groove (9), the joint of the top surface of the main box body (1) and the splicing groove (9) is provided with a splicing bulge (10), the splicing bulge (10) extends into the splicing groove (9) to be connected in a clamping manner, the inner side of the splicing box body (2) is integrally provided with a positioning plate (4), the top surface of the positioning plate (4) is provided with a plurality of positioning holes (5) at equal intervals, a reagent pipe (6) is placed inside the positioning holes (5), the bottom of the main box body (1) is provided with a constant temperature backing plate (7), the joint of the lower end of the inner side surface of the main box body (1) and the constant temperature backing plate (7) is provided with an installation chute (8), one end of the installation chute (8) penetrates through one side surface of the main box body (1) and is communicated with the outside, the utility model discloses a reagent kit, including the constant temperature backing plate (7), the opening position of installation spout (8) is extended to one side surface of constant temperature backing plate (7), and one side surface of constant temperature backing plate (7) is provided with connecting plate (3) for the outside of main box body (1), be provided with card hole (11) on connecting plate (3), the opening edge of installation spout (8) is provided with plastics buckle (12), plastics buckle (12) align with card hole (11), and plastics buckle (12) pass card hole (11) block and connect, the bottom of reagent pipe (6) extends to in main box body (1), and the bottom and the laminating of constant temperature backing plate (7) of reagent pipe (6), the top edge of reagent pipe (6) is provided with extends the ring, extend the ring and laminate with the top opening edge of locating hole (5).

2. The kit for detecting antinuclear antibody spectra, which is convenient to handle, according to claim 1, characterized in that: the extension ring and the reagent tube (6) are of an integrated structure, and the diameter of the extension ring is 5mm larger than that of the positioning hole (5).

3. The kit for detecting antinuclear antibody spectra, which is convenient to handle, according to claim 1, characterized in that: the splicing groove (9) is of a rectangular annular structure, and the size and the shape of the splicing groove (9) are consistent with those of the splicing protrusion (10).

4. The kit for detecting antinuclear antibody spectra, which is convenient to handle, according to claim 1, characterized in that: the end part of the plastic buckle (12) is of a hook-shaped structure, and an inclined plane inclined by forty-five degrees is arranged on the outer side of the hook-shaped structure.

5. The kit for detecting antinuclear antibody spectra, which is convenient to handle, according to claim 1, characterized in that: the lower floor of constant temperature backing plate (7) is provided with the rock wool layer, the upper strata of constant temperature backing plate (7) is provided with the rubber layer.