CN215218569U - Automatic slice scanning device - Google Patents
Automatic slice scanning device Download PDFInfo
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- CN215218569U CN215218569U CN202120875176.7U CN202120875176U CN215218569U CN 215218569 U CN215218569 U CN 215218569U CN 202120875176 U CN202120875176 U CN 202120875176U CN 215218569 U CN215218569 U CN 215218569U
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Abstract
The utility model provides an automatic slice scanning device, which comprises a base (1), a slide suction device (2) arranged on the base (1), a microscope device (3) and a slide box (4); the slide suction device (2) is used for sucking the slide in the slide box (4) to the microscope device (3); the microscope device (3) is used for automatically scanning and detecting cells on the glass slide; the slide box (4) is used for accommodating slides. The utility model discloses a carry out automatic absorption, automatic scanning to the slide glass and detect, realize automatic sliced scanning, simple structure, reliable, convenient operation.
Description
Technical Field
The utility model belongs to the technical field of microscope automatic scanning, particularly, relate to an automatic change section scanning device.
Background
The pathological section is that part of the tissue or organ with pathological changes is treated by various chemicals and embedding method, and then is fixed and hardened, and cut into slices on a microtome, and the slices are adhered on a glass slide, and stained with various colors for examination under a microscope, so as to observe pathological changes and make pathological diagnosis, and provide help for clinical diagnosis and treatment. However, when the traditional pathological section scanner is used for fixing the glass slide with pathological sections, the operation is complicated, the glass slide needs to be replaced manually when needing to be replaced, the working efficiency is extremely low, and the phenomenon of misoperation is avoided due to manual operation, so that troubles are brought to the diagnosis work; meanwhile, because the structure of the existing device is old, the precision is low, the slide glass is difficult to be fixed at the accurate position, the operation is inconvenient and cannot be automated, and the manual operation causes low efficiency, and the stability is poor, so that the pathological change of subsequent observation sections is influenced, therefore, an automatic section scanner needs to be designed, and the working efficiency is improved.
Disclosure of Invention
An object of the utility model is to provide an automatic change section scanning device that can absorb the slide automatically and carry out automatic scanning to prior art not enough.
In order to achieve the purpose, the utility model provides an automatic slice scanning device, which comprises a base, a slide suction device arranged on the base, a microscope device and a slide box; the slide suction device is used for sucking the slide glass in the slide box to the microscope device; the microscope device is used for automatically scanning and detecting the cells on the glass slide; the slide box is used for accommodating slides.
Preferably, the base comprises an installation plate and feet arranged on the installation plate, and the feet are provided with four pieces.
Preferably, the slide suction device comprises an X-axis driving mechanism, a Y-axis driving mechanism, a Z-axis driving mechanism and a suction mechanism; the X-axis driving mechanism is arranged on the mounting plate, and the driving end of the X-axis driving mechanism is connected with the Y-axis driving mechanism and is used for driving the Y-axis driving mechanism to perform displacement in the X-axis direction; the driving end of the Y-axis driving mechanism is connected with the Z-axis driving mechanism and is used for driving the Z-axis driving mechanism to perform displacement in the Y-axis direction; the driving end of the Z-axis driving mechanism is connected with the suction mechanism and is used for driving the suction mechanism to perform displacement in the Z-axis direction;
preferably, the suction mechanism is used for sucking the slide glass positioned in the slide box to the microscope device.
As a further aspect of the present invention, the suction mechanism includes a displacement mechanism and a suction cup, the displacement mechanism is mounted on the Z-axis driving mechanism for driving the suction cup to displace; the sucker is arranged on the displacement mechanism and used for sucking the glass slide.
As a further aspect of the present invention, the microscope device includes a microscope, a stage mechanism, a Z-axis autofocus mechanism, and a holder; the microscope is arranged on the bracket and used for scanning the glass slide; the objective table is arranged on the bracket, is arranged below the microscope and is used for placing a glass slide; the Z-axis automatic focusing mechanism is arranged on the microscope and is used for carrying out automatic focusing according to the position of the glass slide; the bracket is mounted on the mounting plate and used for supporting the microscope and the objective table mechanism.
As a further aspect of the utility model, Z axle autofocus mechanism includes linking bridge, motor, slide rail, installing support and reading head, the linking bridge is used for being connected with the microscope, the both ends of motor are connected with linking bridge and installing support respectively for the drive installing support carries out the displacement on the slide rail, the installing support is used for installing the reading head to the drive through the motor makes the reading head carry out the displacement, thereby realizes autofocus.
As a further proposal of the utility model, the objective table mechanism comprises an objective table, a clamping mechanism and a resetting mechanism which are arranged on the objective table; the objective table is used for being connected with an electric platform of the microscope; the clamping mechanism is used for clamping the glass slide and comprises a fixed support, a right movable plate, a middle connecting plate and a left movable plate, and the fixed support, the right movable plate and the left movable plate are respectively arranged on the objective table and are used for respectively clamping and fixing the four sides of the glass slide; the reset mechanism is used for driving the clamping mechanism to automatically clamp the glass slide, and comprises a reset end, a connecting rod and an elastic piece, wherein the reset end is arranged on the right movable plate, the connecting rod is connected with the objective table, and two ends of the elastic piece are respectively connected with the reset end and the connecting rod and used for automatically clamping the glass slide through the right movable plate and the left movable plate through the elasticity of the elastic piece.
The slide box comprises a box frame and a tray; the box frame is arranged on the mounting plate and used for placing the tray; the tray is arranged on the box frame and used for placing the glass slide.
As a further aspect of the present invention, a pull rail is further provided between the tray and the box rack, and the pull rail is used to make the tray move in a telescopic manner relative to the box rack.
As a further aspect of the present invention, the tray is preferably provided with 6 pieces, and each piece can hold 20 slides.
Compared with the prior art, the utility model discloses following beneficial effect has:
(1) the utility model discloses a carry out automatic absorption, automatic scanning to the slide glass and detect, realize automatic sliced scanning, simple structure, reliable, convenient operation.
(2) The utility model discloses in through set up the lower margin on the base, make it place the convenience.
(3) The utility model discloses in through the drive that sets up X axle, Y axle and Z axle, make it effectively absorb the slide glass on the slide case.
(4) The utility model discloses well adoption sucking disc absorbs the slide glass, makes its absorption reliable, and can not harm the slide glass.
(5) The utility model discloses in through setting up Z axle automatic focusing mechanism to effectively guarantee the scanning validity of microscope to the slide glass.
(6) The utility model discloses in through the clamping mechanism who sets up the slide glass, make the slide glass can effective location.
(7) The utility model discloses in through set up on the slide frame and draw the rail to effectively realize the displacement of tray on the tank tower, so that suction means is to the absorption of slide glass.
(8) The utility model discloses in through setting up a plurality of tray to realize the continuous scanning to the slide glass.
In addition to the above-described objects, features and advantages, the present invention has other objects, features and advantages. The present invention will be described in further detail with reference to the drawings.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this application, are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification. In the drawings:
FIG. 1 is an axial view of the overall structure of the present invention;
FIG. 2 is a schematic axial view of the suction mechanism of the present invention;
FIG. 3 is a schematic structural diagram of the Z-axis automatic focusing mechanism of the present invention;
fig. 4 is a schematic structural diagram of the objective table of the present invention.
Wherein:
1. the device comprises a base, 1-1 parts, a mounting plate, 1-2 parts, feet, 2 parts, a slide sucking device, 2-1 parts, an X-axis driving mechanism, 2-2 parts, a Y-axis driving mechanism, 2-3 parts, a Z-axis driving mechanism, 2-4 parts, a sucking mechanism, 2-41 parts, a connecting plate, 2-42 parts, a sucker, 3 parts, a microscope device, 3-1 parts, a microscope, 3-2 parts, a stage mechanism, 3-21 parts, a stage, 3-22 parts, a fixed support, 3-23 parts, a right movable plate, 3-24 parts, a middle connecting plate, 3-25 parts, a left movable plate, 3-26 parts, a reset end, 3-27 parts, a connecting rod, 3-28 parts, an elastic part, 3-3 parts, a Z-axis automatic focusing mechanism, 3-31 parts, a connecting support, 3-32 parts, a motor, 3-33 parts, 3-34 parts of sliding rail, 3-35 parts of mounting bracket, 3-4 parts of reading head, 4 parts of bracket, 4 parts of slide box, 4-1 parts of box frame, 4-2 parts of tray.
Detailed Description
The embodiments of the invention will be described in detail hereinafter with reference to the accompanying drawings, but the invention can be implemented in many different ways, which are defined and covered by the claims.
In order to make the above objects, features, advantages, and the like of the present invention more clearly understandable, embodiments of the present invention will be described in detail below with reference to the accompanying drawings. It should be noted that the drawings of the utility model all adopt simplified forms and all use non-precise proportions, and are only used for conveniently and clearly assisting in explaining the implementation of the utility model; the number mentioned in the present invention is not limited to the specific number in the example of the drawings; the directions or positional relationships indicated in the "front" middle "rear" left "right" upper "lower" top "bottom" middle "etc. in the present invention are all based on the directions or positional relationships shown in the drawings of the present invention, and do not indicate or suggest that the indicated device or component must have a specific direction, and cannot be understood as a limitation of the present invention.
In this embodiment:
referring to fig. 1 to 3, the present invention provides an automatic slice scanning device, which includes a base 1, a slide suction device 2 disposed on the base 1, a microscope device 3, and a slide box 4; the slide suction device 2 is used for sucking the slide in the slide box 4 to the microscope device 3; the microscope device 3 is used for automatically scanning and detecting cells on the glass slide; the slide cassette 4 is used to house slides.
The base 1 comprises an installation plate 1-1 and four feet 1-2 arranged on the installation plate 1-1, and the feet 1-2 are provided with four pieces.
The slide suction device 2 comprises an X-axis driving mechanism 2-1, a Y-axis driving mechanism 2-2, a Z-axis driving mechanism 2-3 and a suction mechanism 2-4; the X-axis driving mechanism 2-1 is arranged on the mounting plate 1-1, and the driving end of the X-axis driving mechanism is connected with the Y-axis driving mechanism 2-2 and is used for driving the Y-axis driving mechanism 2-2 to perform displacement in the X-axis direction; the driving end of the Y-axis driving mechanism 2-2 is connected with the Z-axis driving mechanism 2-3 and is used for driving the Z-axis driving mechanism 2-3 to perform displacement in the Y-axis direction; the driving end of the Z-axis driving mechanism 2-3 is connected with the suction mechanism 2-4 and is used for driving the suction mechanism 2-4 to perform displacement in the Z-axis direction; the suction mechanism 2-4 is used to suck the slide located in the slide magazine 4 onto the microscope device 3.
Preferably, the suction mechanism 2-4 comprises a displacement mechanism and a sucker, and the displacement mechanism is mounted on the Z-axis driving mechanism 2-3 and used for driving the sucker to displace; the sucker is arranged on the displacement mechanism and used for sucking the glass slide.
The microscope device 3 comprises a microscope 3-1, an object stage mechanism 3-2, a Z-axis automatic focusing mechanism 3-3 and a support 3-4; the microscope 3-1 is arranged on the bracket 3-4 and is used for scanning the glass slide; the objective table 3-2 is arranged on the bracket 3-4, is arranged below the microscope 3-1 and is used for placing a glass slide; the Z-axis automatic focusing mechanism 3-3 is arranged on the microscope 3-1 and is used for carrying out automatic focusing according to the position of the glass slide; the support 3-4 is mounted on the mounting plate 1-1 for supporting the microscope 3-1 and the stage mechanism 3-2.
Preferably, the Z-axis automatic focusing mechanism 3-3 comprises a connecting bracket 3-31, a motor 3-32, a sliding rail 3-22, a mounting bracket 3-34 and a reading head 3-35, wherein the connecting bracket 3-31 is used for being connected with the microscope 3-1, two ends of the motor 3-32 are respectively connected with the connecting bracket 3-31 and the mounting bracket 3-34 and are used for driving the mounting bracket 3-34 to displace on the sliding rail 3-33, and the mounting bracket 3-34 is used for mounting the reading head 3-35 so as to displace the reading head 3-35 through the driving of the motor 3-32, thereby realizing automatic focusing.
The slide box 4 comprises a box frame 4-1 and a tray 4-2; the box frame 4-1 is arranged on the mounting plate 1-1 and used for placing the tray 4-2; the tray 4-2 is arranged on the box frame 4-1 and used for placing glass slides.
Preferably, a pull rail is further arranged between the tray 4-2 and the box frame 4-1, and the pull rail is used for enabling the tray 4-2 to be capable of performing telescopic displacement relative to the box frame 4-1.
Preferably, the tray 4-2 is preferably provided with 6 pieces, and each piece can be provided with 20 slides.
As a further embodiment of the present invention, referring to fig. 3, the objective table mechanism 3-2 comprises an objective table 3-21, a clamping mechanism and a resetting mechanism disposed on the objective table 3-21; the object stage 3-21 is used for being connected with an electric platform of the microscope 3-1; the clamping mechanism is used for clamping the glass slide and comprises a fixed support 3-22, a right movable plate 3-23, a middle connecting plate 3-24 and a left movable plate 3-25, wherein the fixed support 3-22, the right movable plate 3-23 and the left movable plate 3-25 are respectively arranged on the object stage 3-21 and are used for respectively clamping and fixing the four sides of the glass slide; the reset mechanism is used for driving the clamping mechanism to automatically clamp the glass slide and comprises a reset end 3-26, a connecting rod 3-27 and an elastic piece 3-28, the reset end 3-26 is arranged on the right movable plate 3-23, the connecting rod 3-27 is connected with the objective table 3-21, and two ends of the elastic piece 3-28 are respectively connected with the reset end 3-26 and the connecting rod 3-27 and used for enabling the right movable plate 3-23 and the left movable plate to automatically clamp the glass slide through the elasticity of the elastic piece 3-28.
The utility model discloses a working procedure specifically as follows:
manually placing the glass slide with the cells and the cover glass on a tray;
starting a slide suction device, sucking the slide placed in the tray, and placing the slide on an objective table;
automatically scanning the glass slide on the objective table by the microscope;
when the scanning is finished, the slide suction device sucks the slide into the tray, and the scanning of one slide is finished.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. An automatic change section scanning device which characterized in that: comprises a base (1), a slide suction device (2) arranged on the base (1), a microscope device (3) and a slide box (4);
the slide suction device (2) is used for sucking the slide in the slide box (4) to the microscope device (3);
the microscope device (3) is used for automatically scanning and detecting cells on the glass slide;
the slide box (4) is used for accommodating slides.
2. The automated slice scanning apparatus of claim 1, wherein: the base (1) comprises an installation plate (1-1) and four ground feet (1-2) arranged on the installation plate (1-1), and the four ground feet (1-2) are arranged.
3. The automated slice scanning apparatus of claim 1, wherein: the slide suction device (2) comprises an X-axis driving mechanism (2-1), a Y-axis driving mechanism (2-2), a Z-axis driving mechanism (2-3) and a suction mechanism (2-4);
the X-axis driving mechanism (2-1) is arranged on the mounting plate (1-1), and the driving end of the X-axis driving mechanism is connected with the Y-axis driving mechanism (2-2) and is used for driving the Y-axis driving mechanism (2-2) to perform displacement in the X-axis direction;
the driving end of the Y-axis driving mechanism (2-2) is connected with the Z-axis driving mechanism (2-3) and is used for driving the Z-axis driving mechanism (2-3) to perform displacement in the Y-axis direction;
the driving end of the Z-axis driving mechanism (2-3) is connected with the suction mechanism (2-4) and is used for driving the suction mechanism (2-4) to perform displacement in the Z-axis direction;
the suction mechanism (2-4) is used for sucking the slide glass positioned in the slide box (4) to the microscope device (3).
4. The automated slice scanning apparatus of claim 3, wherein: the suction mechanism (2-4) comprises a displacement mechanism and a sucker, and the displacement mechanism is mounted on the Z-axis driving mechanism (2-3) and used for driving the sucker to displace; the sucker is arranged on the displacement mechanism and used for sucking the glass slide.
5. The automated slice scanning apparatus of claim 1, wherein: the microscope device (3) comprises a microscope (3-1), an object stage mechanism (3-2), a Z-axis automatic focusing mechanism (3-3) and a bracket (3-4);
the microscope (3-1) is arranged on the bracket (3-4) and is used for scanning the glass slide;
the object stage (3-2) is arranged on the bracket (3-4), is arranged below the microscope (3-1) and is used for placing a glass slide;
the Z-axis automatic focusing mechanism (3-3) is arranged on the microscope (3-1) and is used for carrying out automatic focusing according to the position of the glass slide;
the support (3-4) is arranged on the mounting plate (1-1) and is used for supporting the microscope (3-1) and the objective table mechanism (3-2).
6. The automated slice scanning apparatus of claim 5, wherein: the Z-axis automatic focusing mechanism (3-3) comprises a connecting support, a motor, a sliding rail, a mounting support and a reading head, wherein the connecting support is used for being connected with a microscope, two ends of the motor are respectively connected with the connecting support and the mounting support and used for driving the mounting support to displace on the sliding rail, and the mounting support is used for mounting the reading head so as to enable the reading head to displace through the driving of the motor, so that automatic focusing is realized.
7. The automated slice scanning apparatus of claim 6, wherein: the objective table mechanism (3-2) comprises an objective table (3-21), a clamping mechanism and a reset mechanism, wherein the clamping mechanism and the reset mechanism are arranged on the objective table (3-21);
the object stage (3-21) is used for being connected with an electric platform of the microscope (3-1);
the clamping mechanism is used for clamping the glass slide and comprises a fixed support (3-22), a right movable plate (3-23), a middle connecting plate (3-24) and a left movable plate (3-25), and the fixed support (3-22), the right movable plate (3-23) and the left movable plate (3-25) are respectively arranged on the object stage (3-21) and are used for respectively clamping and fixing the four sides of the glass slide;
the reset mechanism is used for driving the clamping mechanism to automatically clamp the glass slide and comprises a reset end (3-26), a connecting rod (3-27) and an elastic piece (3-28), the reset end (3-26) is arranged on the right movable plate (3-23), the connecting rod (3-27) is connected with the objective table (3-21), and two ends of the elastic piece (3-28) are respectively connected with the reset end (3-26) and the connecting rod (3-27) and used for enabling the right movable plate (3-23) and the left movable plate to automatically clamp the glass slide through the elasticity of the elastic piece (3-28).
8. The automated slice scanning apparatus of claim 1, wherein: the slide box (4) comprises a box frame (4-1) and a tray (4-2);
the box frame (4-1) is arranged on the mounting plate (1-1) and used for placing the tray (4-2);
the tray (4-2) is arranged on the box frame (4-1) and used for placing glass slides.
9. The automated slice scanning apparatus of claim 8, wherein: and a pull rail is also arranged between the tray (4-2) and the box frame (4-1), and the pull rail is used for enabling the tray (4-2) to be capable of performing telescopic displacement relative to the box frame (4-1).
10. The automated slice scanning apparatus of claim 9, wherein: the tray (4-2) is provided with one or more than one slide glass, and each slide glass can be placed on one or more than one tray.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120875176.7U CN215218569U (en) | 2021-04-26 | 2021-04-26 | Automatic slice scanning device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120875176.7U CN215218569U (en) | 2021-04-26 | 2021-04-26 | Automatic slice scanning device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215218569U true CN215218569U (en) | 2021-12-17 |
Family
ID=79450918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120875176.7U Active CN215218569U (en) | 2021-04-26 | 2021-04-26 | Automatic slice scanning device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215218569U (en) |
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2021
- 2021-04-26 CN CN202120875176.7U patent/CN215218569U/en active Active
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