CN215139273U - Virus inactivation blending instrument - Google Patents
Virus inactivation blending instrument Download PDFInfo
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- CN215139273U CN215139273U CN202121322038.2U CN202121322038U CN215139273U CN 215139273 U CN215139273 U CN 215139273U CN 202121322038 U CN202121322038 U CN 202121322038U CN 215139273 U CN215139273 U CN 215139273U
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- water
- reaction tank
- sample
- reciprocating
- sample basket
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- 238000002156 mixing Methods 0.000 title claims abstract description 38
- 230000002779 inactivation Effects 0.000 title claims abstract description 30
- 241000700605 Viruses Species 0.000 title claims abstract description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 108
- 238000006243 chemical reaction Methods 0.000 claims abstract description 52
- 238000010438 heat treatment Methods 0.000 claims abstract description 10
- 230000010355 oscillation Effects 0.000 claims abstract description 10
- 238000009210 therapy by ultrasound Methods 0.000 claims abstract description 6
- 150000001875 compounds Chemical class 0.000 claims description 6
- 238000001914 filtration Methods 0.000 abstract description 4
- 150000007523 nucleic acids Chemical class 0.000 abstract description 3
- 102000039446 nucleic acids Human genes 0.000 abstract description 3
- 108020004707 nucleic acids Proteins 0.000 abstract description 3
- 238000000605 extraction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 description 7
- 238000005034 decoration Methods 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 210000001989 nasopharynx Anatomy 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 241000711573 Coronaviridae Species 0.000 description 1
- 240000003186 Stachytarpheta cayennensis Species 0.000 description 1
- 235000009233 Stachytarpheta cayennensis Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model provides a virus inactivation mixing instrument, which has the main functions of constant temperature heating, can be realized by adjusting the circulating water temperature of a reaction tank, realizes the heating of the circulating water through a water heater, temporarily stores the circulating water reaching the set temperature in a water storage tank, inputs the circulating water into the reaction tank through a water pump after the water temperature in the reaction tank is reduced so as to keep the water temperature in the reaction tank constant, and performs coarse filtration through a filter; ultrasonic oscillation is realized through an ultrasonic generator, so that the specimen in the specimen basket in the reaction tank is subjected to ultrasonic treatment, and the functions of uniform mixing, oscillation and the like are realized; reciprocating oscillation, namely erecting a sample in a sample basket, clamping and fixing the sample by using a sample fixing plate, and then connecting the sample basket with a reciprocating oscillator through a reciprocating oscillator gripper; the virus inactivation blending instrument does not need to convert an instrument, can directly combine the inactivation step and the blending step, reduces the risk of specimen pollution and leakage, and ensures that the release and extraction of virus nucleic acid are more sufficient.
Description
Technical Field
The utility model belongs to the technical field of the medical equipment technique and specifically relates to a virus inactivation mixing appearance.
Background
The existing instrument for processing the nasopharyngeal swab specimen for detecting the new coronavirus nucleic acid is single in function, and two steps of inactivation and uniform mixing need to be carried out on two or more instruments and cannot be carried out simultaneously.
According to the current procedure, the specimen is transferred to the mixing apparatus after 30 minutes of inactivation, where the specimen holder is sometimes replaced, and the specimen is discharged again. For some specimens at risk of infection, the specimen may be contaminated or even leaked with each additional step and one minute of prolonged operation. At the same time, each additional instrument increases the cost of economy, space, and maintenance for the laboratory.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the technical problem that a virus inactivation mixing appearance is provided, the mixing appearance collects constant temperature heating and sample mixing in the instrument of an organic whole.
In order to solve the technical problem, the technical scheme of the utility model is that:
a virus inactivation blending machine comprises a machine body and a sample basket, wherein a reaction tank (A.1.3) is arranged in the machine body, the reaction tank (A.1.3) is divided into an upper part and a lower part (separated by a dotted line), the upper part is used for reciprocating oscillation, the lower part is used for ultrasound and heating, the sample basket is arranged in the reaction tank, wherein,
the sample basket is of an open structure above, a fixing groove (B.1.5) is designed on the side face of a sample basket main body (B.1.1) and used for being connected with a reciprocating type oscillator fixer (A.6.2) of a machine body, a fixing plate (B.1.2) used for fixing a sample frame is arranged on the inner side of the sample basket, and the distance between the two fixing plates can be adjusted by adjusting a fixing screw (B.1.3) so as to adapt to sample frames of different specifications;
the machine body further comprises a water circulation system, a water heater (A.2.1), a water storage tank (A.2.2), a filter (A.2.3), a water pump (A.2.4), a temperature and water level sensor (A.2.5), an ultrasonic generator (A.3.1), a reaction tank cover plate (A.4.1), an operation panel (A.5.1) and a reciprocating type oscillator motor (A.6.1), wherein the water circulation system comprises a water inlet (A.1.1), a water outlet (A.1.2), a circulating pipe (A.1.4) and a water outlet control valve (A.1.5), the water inlet, the water outlet and the circulating pipe are respectively communicated with the reaction tank (A.1.3), and the water outlet control valve (A.1.5) is arranged at the water outlet and is used for controlling water drainage; the water heater (A.2.1), the water storage tank (A.2.2), the filter (A.2.3) and the water pump (A.2.4) are sequentially arranged on the circulating pipe (A.1.4), the temperature and water level sensor (A.2.5) and the ultrasonic generator (A.3.1) are respectively arranged at the bottom of the reaction tank (A.1.3), the reaction tank cover plate (A.4.1) is arranged at the top of the reaction tank (A.1.3), the compound oscillator motor (A.6.1) is arranged outside the reaction tank (A.1.3) and is fixedly connected with the reciprocating oscillator fixer (A.6.2), and the operation panel (A.5.1) is respectively connected with the water outlet control valve (A.1.5), the water heater (A.2.1), the temperature sensor (A.2.5), the ultrasonic generator (A.3.1) and the reciprocating oscillator motor (A.6.1) in a line control mode.
The water heater (A.2.1) is used for adjusting the temperature of circulating water in the reaction tank, the water storage tank (A.2.2) is used for temporarily storing the circulating water, the filter (A.2.3) is used for filtering the circulating water, the water pump (A.2.4) is used for injecting water into the reaction tank, and the temperature and water level sensor (A.2.5) is used for detecting the water level and the temperature in the reaction tank.
Preferably, above-mentioned virus inactivation blending machine, be equipped with on compound oscillator fixer (A.6.2) be used for with the fixed slot (B.1.5) fixed connection's of sample basket tongs (A.6.2.2), reciprocating type oscillator embeds sawtooth formula guide rail (A.6.2.3) that is used for realizing the interval adjustment, tongs (A.6.2.2) and sawtooth formula guide rail (A.6.2.3) fixed connection adjust the interval along with the motion of sawtooth formula guide rail (A.6.2.3) to it is fixed through adjusting screw (A.6.2.1).
Preferably, in the above virus inactivation and mixing apparatus, the front surface and the bottom surface of the sample basket main body (b.1.1) are designed to be of a net structure.
Preferably, in the virus inactivation and mixing instrument, a handle (b.1.4) is arranged above the side surface of the sample basket body.
Preferably, in the virus inactivation and mixing instrument, the cover plate (A.4.1) of the reaction tank is designed to be a transparent structure.
Has the advantages that:
above-mentioned virus inactivation blending appearance need not change the instrument, can directly combine two steps of inactivation and mixing, has both practiced thrift the time, has reduced the operating procedure, has practiced thrift the cost of economy, space and maintenance again, and more importantly has reduced the risk that the sample pollutes and leaks and the release of virus nucleic acid and extract more abundant, when protecting operating personnel and laboratory environment, more is favorable to more fast more accurate screening positive patient.
Drawings
Fig. 1 is a blue top view of a sample of the virus inactivation mixing apparatus of the present invention.
Fig. 2 is a first side view of a sample blue of the virus inactivation and mixing instrument of the present invention.
Fig. 3 is a blue second side view of a sample of the virus inactivation and mixing apparatus of the present invention.
Fig. 4 is a side view of the body of the virus inactivation and mixing instrument of the present invention.
In the figure: a.1.1: water inlet, a.1.2: water outlet, a.1.3: reaction tank, a.1.4: circulation tube, a.1.5: outlet control valve, a.2.1: water heater, a.2.2: water storage tank, a.2.3: filter, a.2.4: water pump, a.2.5: temperature water level sensor, a.3.1: ultrasonic generator, a.4.1: reaction tank cover plate, a.5.1: operating panel, a.6.1: reciprocating oscillator motor, a.6.2: multiple oscillator fixture, a.6.2.1: adjusting screw, a.6.2.2: gripper, a.6.2.3: zigzag guide rail, b.1.1: sample basket body, b.1.2: fixed plate, b.1.3: set screw, b.1.4: handle, b.1.5: fixing groove
Detailed Description
Example 1
As shown in fig. 1-4, the virus inactivation and mixing instrument comprises a machine body and a sample basket, wherein a reaction tank A.1.3 is arranged in the machine body, the reaction tank A.1.3 is divided into an upper part and a lower part (separated by a dotted line), the upper part is used for reciprocating oscillation, the lower part is used for ultrasonic treatment and heating, the sample basket is arranged in the reaction tank, a handle B.1.4 is arranged above the side surface of the sample basket main body, wherein,
the sample basket is of an open structure above, the front surface and the bottom surface of a sample basket main body B.1.1 are designed to be of a net structure, the side surface of the main body is provided with a fixing groove B.1.5 for being connected with a reciprocating oscillator fixer A.6.2 of a machine body, the inner side of the sample basket is provided with a fixing plate B.1.2 for fixing a sample frame, and the distance between the two fixing plates can be adjusted by adjusting a fixing screw B.1.3 so as to adapt to sample frames of different specifications;
the machine body further comprises a water circulation system, a water heater A.2.1, a water storage tank A.2.2, a filter A.2.3, a water pump A.2.4, a temperature and water level sensor A.2.5, an ultrasonic generator A.3.1, a reaction tank cover plate A.4.1, an operation panel A.5.1 and a reciprocating oscillator motor A.6.1, wherein the water circulation system comprises a water inlet A.1.1, a water outlet A.1.2, a circulating pipe A.1.4 and a water outlet control valve A.1.5, the water inlet, the water outlet and the circulating pipe are respectively communicated with the reaction tank A.1.3, and the water outlet control valve A.1.5 is arranged at a water outlet and used for controlling water drainage; the water heater A.2.1, the water storage tank A.2.2, the filter A.2.3 and the water pump A.2.4 are sequentially arranged on the circulating pipe A.1.4, the temperature and water level sensor A.2.5 and the ultrasonic generator A.3.1 are respectively arranged at the bottom of the reaction tank A.1.3, the reaction tank cover plate A.4.1 is designed to be a transparent structure, the reaction tank cover plate A.4.1 is arranged at the top of the reaction tank A.1.3, the compound oscillator motor A.6.1 is arranged outside the reaction tank A.1.3 and is fixedly connected with the reciprocating oscillator fixer A.6.2, and the operation panel A.5.1 is respectively in line control connection with the water outlet control valve A.1.5, the water heater A.2.1, the temperature and water level sensor A.2.5, the ultrasonic generator A.3.1 and the reciprocating oscillator motor A.6.1.
The compound oscillator fixer A.6.2 is provided with a hand grip A.6.2.2 which is fixedly connected with a fixing groove B.1.5 of the sample basket, a zigzag guide rail A.6.2.3 for realizing interval adjustment is arranged in the reciprocating oscillator, the hand grip A.6.2.2 is fixedly connected with the zigzag guide rail A.6.2.3, the interval is adjusted along with the movement of the zigzag guide rail A.6.2.3, and the hand grip is fixed through an adjusting screw A.6.2.1.
The water heater A.2.1 is used for adjusting the temperature of circulating water in the reaction tank, the water storage tank A.2.2 is used for temporarily storing the circulating water, the filter A.2.3 is used for filtering the circulating water, the water pump A.2.4 is used for injecting water into the reaction tank, and the temperature and water level sensor A.2.5 is used for detecting the water level and the temperature in the reaction tank.
The use method of the virus inactivation and mixing instrument comprises the following steps:
firstly, a sample frame is placed in a sample basket of the machine, and is clamped and fixed by a sample frame fixing plate, and then is placed in circulating water at the lower part of a reaction tank, so that constant-temperature heating and ultrasonic treatment can be carried out, and the constant-temperature heating and the ultrasonic treatment can be carried out simultaneously or in a distributed manner. And then lifting the sample basket to the upper part of the reaction tank through a sample basket lifting handle and connecting the sample basket with a reciprocating type oscillator gripper, and adjusting the distance between the grippers through adjusting an adjusting screw on the gripper so as to fix the sample basket. After the sample basket is fixed, mechanical reciprocating oscillation with certain time and frequency can be carried out, and the function can realize uniform mixing of samples in the basket and primary throwing of residual circulating water.
The water adding of the virus inactivation and mixing instrument is designed to be manual, and a water adding port can be connected with a water tap or a hose; the water outlet is designed with a control valve, and a manual valve or an electromagnetic control valve can be selected. The reaction tank cover plate is designed to be a transparent structure, and the reaction process in the tank can be observed.
In conclusion, the main functions of the virus inactivation and mixing instrument comprise constant-temperature heating, which can be realized by adjusting the circulating water temperature of the reaction tank, the heating of the circulating water is realized by a water heater, the circulating water reaching the set temperature is temporarily stored in a water storage tank, after the water temperature in the reaction tank is reduced, the circulating water is input into the reaction tank through a water pump to keep the water temperature in the reaction tank constant, and coarse filtration is carried out through a filter; ultrasonic oscillation is realized through an ultrasonic generator, so that the specimen in the specimen basket in the reaction tank is subjected to ultrasonic treatment, and the functions of uniform mixing, oscillation and the like are realized; reciprocating type vibrates, erects the sample in the sample basket to it is fixed to carry out the centre gripping with the sample fixed plate, and later is connected the sample basket through reciprocating type oscillator tongs and reciprocating type oscillator.
After the nasopharynx swab specimen tube is put into the instrument, the nasopharynx swab specimen tube is uniformly mixed while being inactivated at constant temperature, wherein the constant temperature inactivation process can adopt a dry method or a wet method; the blending process can also be selected by self, and is divided into: vortex oscillation, ultrasonic mixing, vortex ultrasonic mixing and the like. Meanwhile, only the blending operation can be carried out on the specimen which does not need to be inactivated.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (5)
1. The utility model provides a virus inactivation blending appearance which characterized in that: comprises a machine body and a sample basket, wherein a reaction tank (A.1.3) is arranged in the machine body, the reaction tank (A.1.3) is divided into an upper part and a lower part, the upper part is used for reciprocating oscillation, the lower part is used for ultrasonic treatment and heating, the sample basket is arranged in the reaction tank, wherein,
the upper part of the sample basket is of an open structure, a fixing groove (B.1.5) is designed on the side surface of a sample basket main body (B.1.1) and used for being connected with a reciprocating type oscillator fixer (A.6.2) of a machine body, and a fixing plate (B.1.2) used for fixing a sample frame is arranged on the inner side of the sample basket;
the machine body further comprises a water circulation system, a water heater (A.2.1), a water storage tank (A.2.2), a filter (A.2.3), a water pump (A.2.4), a temperature and water level sensor (A.2.5), an ultrasonic generator (A.3.1), a reaction tank cover plate (A.4.1), an operation panel (A.5.1) and a reciprocating type oscillator motor (A.6.1), wherein the water circulation system comprises a water inlet (A.1.1), a water outlet (A.1.2), a circulating pipe (A.1.4) and a water outlet control valve (A.1.5), the water inlet, the water outlet and the circulating pipe are respectively communicated with the reaction tank (A.1.3), and the water outlet control valve (A.1.5) is arranged at the water outlet; the water heater (A.2.1), the water storage tank (A.2.2), the filter (A.2.3) and the water pump (A.2.4) are sequentially arranged on the circulating pipe (A.1.4), the temperature and water level sensor (A.2.5) and the ultrasonic generator (A.3.1) are respectively arranged at the bottom of the reaction tank (A.1.3), the reaction tank cover plate (A.4.1) is arranged at the top of the reaction tank (A.1.3), the compound oscillator motor (A.6.1) is arranged outside the reaction tank (A.1.3) and is fixedly connected with the reciprocating oscillator fixer (A.6.2), and the operation panel (A.5.1) is respectively connected with the water outlet control valve (A.1.5), the water heater (A.2.1), the temperature sensor (A.2.5), the ultrasonic generator (A.3.1) and the reciprocating oscillator motor (A.6.1) in a line control mode.
2. The virus inactivation and mixing instrument according to claim 1, wherein: the compound oscillator fixer (A.6.2) is provided with a gripper (A.6.2.2) fixedly connected with a fixing groove (B.1.5) of the sample basket, the reciprocating oscillator is internally provided with a sawtooth type guide rail (A.6.2.3) used for realizing spacing adjustment, the gripper (A.6.2.2) is fixedly connected with the sawtooth type guide rail (A.6.2.3), the spacing is adjusted along with the movement of the sawtooth type guide rail (A.6.2.3), and the gripper is fixed through an adjusting screw (A.6.2.1).
3. The virus inactivation and mixing instrument according to claim 1, wherein: the front surface and the bottom surface of the sample basket main body (B.1.1) are of a net structure.
4. The virus inactivation and mixing instrument according to claim 1, wherein: a handle (B.1.4) is arranged above the side surface of the sample basket main body.
5. The virus inactivation and mixing instrument according to claim 1, wherein: the reaction tank cover plate (A.4.1) is of a transparent structure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121322038.2U CN215139273U (en) | 2021-06-15 | 2021-06-15 | Virus inactivation blending instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121322038.2U CN215139273U (en) | 2021-06-15 | 2021-06-15 | Virus inactivation blending instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215139273U true CN215139273U (en) | 2021-12-14 |
Family
ID=79385721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121322038.2U Expired - Fee Related CN215139273U (en) | 2021-06-15 | 2021-06-15 | Virus inactivation blending instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215139273U (en) |
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2021
- 2021-06-15 CN CN202121322038.2U patent/CN215139273U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211214 |