CN215133412U - Connecting device convenient for plasma separation, purification and storage - Google Patents
Connecting device convenient for plasma separation, purification and storage Download PDFInfo
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- CN215133412U CN215133412U CN202120202572.3U CN202120202572U CN215133412U CN 215133412 U CN215133412 U CN 215133412U CN 202120202572 U CN202120202572 U CN 202120202572U CN 215133412 U CN215133412 U CN 215133412U
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- 238000003860 storage Methods 0.000 title claims abstract description 28
- 238000000746 purification Methods 0.000 title claims abstract description 24
- 238000000926 separation method Methods 0.000 title claims abstract description 19
- 238000001179 sorption measurement Methods 0.000 claims abstract description 17
- 238000002955 isolation Methods 0.000 claims abstract description 15
- 210000002381 plasma Anatomy 0.000 claims description 78
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 7
- 229910052799 carbon Inorganic materials 0.000 claims description 4
- 239000011347 resin Substances 0.000 claims description 4
- 229920005989 resin Polymers 0.000 claims description 4
- 208000002925 dental caries Diseases 0.000 abstract description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
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- 239000003610 charcoal Substances 0.000 description 2
- 238000005352 clarification Methods 0.000 description 2
- 238000000502 dialysis Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000004623 platelet-rich plasma Anatomy 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- 108010049003 Fibrinogen Proteins 0.000 description 1
- 102000008946 Fibrinogen Human genes 0.000 description 1
- 102000016359 Fibronectins Human genes 0.000 description 1
- 108010067306 Fibronectins Proteins 0.000 description 1
- 108010077077 Osteonectin Proteins 0.000 description 1
- 102100037599 SPARC Human genes 0.000 description 1
- 108090000190 Thrombin Proteins 0.000 description 1
- 102000002938 Thrombospondin Human genes 0.000 description 1
- 108060008245 Thrombospondin Proteins 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 238000007675 cardiac surgery Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 229940012952 fibrinogen Drugs 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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Abstract
The utility model discloses a connecting device convenient to plasma separation purifies and stores belongs to medical supplies technical field. A connection device for facilitating separation, purification and storage of plasma, comprising: the device comprises a connecting bag, a first input pipe, a connecting pipe, an external circulation input pipe and an external circulation output pipe; the interior of the connecting bag is sequentially provided with an adsorption layer and an isolation layer, and the adsorption layer and the isolation layer divide the connecting bag into an input cavity, a circulation cavity and an output cavity in sequence; the first input pipe is communicated with the input cavity, the external circulation input pipe is communicated with the circulation cavity, and the external circulation output pipe and the connecting pipe are respectively communicated with the output cavity. The utility model discloses a to connect the bag and separate for different cavitys, the inside of connecting the bag sets up the adsorbed layer to external other plasma separation purifier, thereby be convenient for separate purification and storage to plasma.
Description
Technical Field
The utility model relates to the technical field of medical supplies, concretely relates to connecting device convenient to plasma separation purifies and stores.
Background
The platelet-rich plasma is a plasma product obtained by performing gradient centrifugal separation on whole blood, and the concentration of platelets is usually 3-5 times of the normal concentration. Its main components are platelets, plasma (plasma protein, fibrinogen), leukocytes and other components (fibronectin, thrombospondin, osteonectin, etc.). In 1977, PRP was first isolated from Harkenig and used for patients after cardiac surgery to achieve good therapeutic effect. In 1984, Okuda et al found that platelet rich plasma extracted from plasma contained various growth factors. In 1993, Hood et al added thrombin and calcium ions to PRP, proposed PG concept, and used the gel-like material formed for tissue repair. Whitman in 1997 pioneered the use of autologous PRP for oral maxillofacial surgery to repair bone tissue. At present, a plasma separation instrument is commonly used for separating and extracting platelet-rich, but the existing plasma bag has a lot of inconvenience in the use process, and the separated plasma is inconvenient to purify, so that the problem that the plasma is inconvenient to separate, purify and store exists in the prior art.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a connecting device convenient to plasma separation purifies and stores to solve among the prior art inconvenient problem of separating purification and storage to plasma.
The utility model provides an above-mentioned technical problem's technical scheme as follows:
a connection device for facilitating separation, purification and storage of plasma, comprising: the device comprises a connecting bag, a first input pipe, a connecting pipe, an external circulation input pipe and an external circulation output pipe; the interior of the connecting bag is sequentially provided with an adsorption layer and an isolation layer, and the adsorption layer and the isolation layer divide the connecting bag into an input cavity, a circulation cavity and an output cavity in sequence; the first input pipe is communicated with the input cavity, the external circulation input pipe is communicated with the circulation cavity, and the external circulation output pipe and the connecting pipe are respectively communicated with the output cavity.
The utility model discloses a connect the bag and pour into plasma to input chamber into through first input tube, the plasma of input intracavity flows into the circulation chamber after the adsorbed layer, and the plasma of circulation intracavity portion receives the effect of blockking of isolation layer can not directly get into the output chamber, and the external plasma clarification plant of extrinsic cycle input tube, for example plasma dialysis machine or plasma filter, the plasma of recirculating intracavity portion purifies the back and flows into the output chamber through extrinsic cycle output tube, finally flows through the connecting pipe. The utility model discloses a to connect the bag and separate for different cavitys to through external other plasma separation or purifier, thereby be convenient for separate purification and storage to plasma.
The utility model discloses a use: (1) the plasma enters the input cavity of the connecting bag through the first input tube; (2) the plasma in the input cavity enters the circulating cavity through the adsorption layer; (3) the plasma in the circulating cavity can not directly enter the output cavity under the isolation action of the isolating layer; (4) the external circulation input tube is connected with other purifying equipment to purify the plasma in the circulation cavity and then flow into the output cavity through the external circulation output tube; (5) the plasma in the output chamber flows out through the connecting tube.
Furthermore, the connecting bags are sequentially detachably connected with a plurality of storage bags through connecting pipes, and the storage bags are also internally provided with adsorption layers.
The utility model discloses a storage bag is convenient for store the plasma after purifying to the inside of every storage bag is equipped with the adsorbed layer and is convenient for carry out repeated absorption to plasma and purify.
Furthermore, the external circulation input pipe is communicated with the bottom of the circulation cavity, the external circulation output pipe is communicated with the top of the output cavity, and the capacity of the output cavity is larger than that of the circulation cavity and the input cavity.
The utility model has the advantages that the external circulation input pipe is communicated with the bottom of the circulation cavity, so that the plasma in the circulation cavity can flow out and circulate conveniently, and the external circulation output pipe is communicated with the top of the output cavity, so that the plasma in the output cavity can be circulated conveniently; and the output cavity has enough capacity to be convenient for plasma preservation.
Further, the first input pipe and the connecting pipe are respectively connected with a flow regulator.
The utility model discloses a flow regulator is through the pipe wall of the first input tube of extrusion and connecting pipe to the realization is to the flow control of first input tube and connecting pipe, and cooperates external plasma clarification plant's purification rate, is favorable to the circulation of plasma to purify.
Further, the first input pipe, the connecting pipe, the external circulation input pipe and the external circulation output pipe are respectively connected with a liquid pipe clamp.
The utility model discloses a liquid pipe clamp is used for centre gripping extrusion pipe wall, and the plasma of being convenient for directly intercepting in the corresponding pipeline flows.
Furthermore, the top of the connecting bag is provided with a hanging hole.
The utility model discloses a hanging hole is convenient for hang and is connected the bag, improves the flexibility of connecting the bag.
Further, the inside of the adsorption layer is filled with activated carbon and resin carbon.
The utility model discloses a thereby active carbon and resin charcoal constitute the adsorbed layer and realize adsorbing the purification to plasma.
The utility model discloses following beneficial effect has:
(1) the utility model discloses a to connect the bag and separate for different cavitys, the inside of connecting the bag sets up the adsorbed layer to external other plasma purifier, thereby be convenient for separate purification and storage to plasma.
(2) The utility model discloses a storage bag is convenient for store the plasma after purifying to the inside of every storage bag is equipped with the adsorbed layer and is convenient for carry out repeated absorption to plasma and purify.
(3) The utility model connects the external circulation input pipe with the bottom of the circulation cavity and the external circulation output pipe with the top of the output cavity, so that the blood plasma in the circulation cavity and the output cavity is more convenient to circulate; and the output cavity has enough capacity to be convenient for plasma preservation.
(4) The utility model discloses a liquid pipe clamp is used for centre gripping extrusion pipe wall, and the plasma of being convenient for directly in the corresponding pipeline of interception flows, can be used to the circulation that certain plasma purified the mode and go on.
Drawings
FIG. 1 is a schematic structural view of a connection device for facilitating separation, purification and storage of blood plasma according to the present invention;
fig. 2 is a schematic structural view of the connection bag of the present invention.
In the figure: 10-a connecting bag; 11-an adsorption layer; 12-an isolation layer; 13-an input cavity; 14-a circulation chamber; 15-an output cavity; 16-hanging holes; 20-storage bag; 21-a first input pipe; 22-connecting tube; 24-external circulation input pipe; 25-external circulation output pipe; 26-a flow regulator; 27-liquid tube clamp.
Detailed Description
The principles and features of the present invention are described below in conjunction with the following drawings, the examples given are only intended to illustrate the present invention and are not intended to limit the scope of the present invention.
Examples
Referring to fig. 1 and 2, a connection device for separating, purifying and storing plasma comprises a connection bag 10, a first input tube 21, a connection tube 22, an external circulation input tube 24 and an external circulation output tube 25. Connect bag 10, first input tube 21, connecting pipe 22, extrinsic cycle input tube 24 and extrinsic cycle output tube 25 and be the TPE material, have the advantage of rubber and plastics concurrently to be convenient for recycle, use cost is lower.
A first inlet tube 21 is connected to the top of the connection bag 10, and plasma is injected into the connection bag 10 through the first inlet tube 21. The inside position that is close to first input tube 21 of connecting bag 10 is equipped with adsorbed layer 11, and the inside packing of adsorbed layer 11 has active carbon and resin charcoal for the inside plasmalexin of adsorbing connecting bag 10 plays the effect of absorption purification. The bottom of the connection bag 10 is connected with a connection tube 22, and the connection tube 22 is used for connecting a transfusion tube to output the plasma inside the connection bag 10. The inside position that is close to connecting pipe 22 of connecting bag 10 is equipped with isolation layer 12, and isolation layer 12 plays the isolation effect, avoids being located the mutual circulation of plasma of isolation layer 12 both sides.
The connection bag 10 is divided into an input chamber 13, a circulation chamber 14, and an output chamber 15 in this order by an adsorption layer 11 and a separation layer. The inlet chamber 13 communicates with the first inlet pipe 21, the external circulation inlet pipe 24 communicates with the circulation chamber 14, and the external circulation outlet pipe 25 and the connection pipe 22 communicate with the outlet chamber 15, respectively. Plasma flows into the input cavity 13 through the first input tube 21, the plasma in the input cavity 13 flows into the circulating cavity 14 after being adsorbed and purified by the adsorption layer 11, and the isolating layer 12 separates the circulating cavity 14 from the output cavity 15 to prevent the plasma in the circulating cavity 14 from directly flowing into the output cavity 15. The external circulation input tube 24 is externally connected with other plasma separation and purification devices, and the plasma inside the circulation chamber 14 is purified in other manners through the external devices, such as plasma dialysis or plasma filtration, so that the separated and purified plasma flows into the output chamber 15 through the external circulation output tube 25 and finally flows out of the connection bag 10 through the connection tube 22.
The internal corners of the connecting bag 10 are rounded, so that the plasma flowing efficiency in the connecting bag 10 is improved, the phenomenon that the plasma does not flow at the corners is avoided, and the circulation purification of the plasma is facilitated. The top of the connecting bag 10 is also provided with a hanging hole 16, the connecting bag 10 can be conveniently hung through the hanging hole 16, and the use flexibility of the connecting bag 10 is improved.
The first input tube 21 and the connecting tube 22 are respectively connected with a flow regulator 26, and the flow regulator 26 extrudes the tube walls of the first input tube 21 and the connecting tube 22, so that the flow regulation of the first input tube 21 and the connecting tube 22 is realized, and the purification speed of the external plasma purification device is matched, thereby being beneficial to the circular purification of plasma. The first input tube 21, the connecting tube 22, the external circulation input tube 24 and the external circulation output tube 25 are respectively connected with a liquid tube clamp 27, and the liquid tube clamp 27 is used for clamping and extruding the tube wall, so that the plasma flowing in the corresponding tube can be directly stopped, and the plasma separation and purification can be suspended.
The connection bag 10 is further sequentially connected with a plurality of storage bags 20 through a connection pipe 22, the number of the storage bags 20 is two, and the inside of the storage bag 20 is also provided with an adsorption layer 11, so that the stored plasma can be conveniently subjected to repeated adsorption and purification. Both the top and bottom of the pouch 20 are provided with ports for connection to the connector 22 to facilitate access to the pouch 20 on demand by providing a detachable connection. The top of the storage bag 20 is also provided with a hanging hole 16 for hanging when used alone. In other embodiments of the present invention, the number of the storage bags 20 can be three, four, five, etc.
The utility model discloses an operation process: (1) the first input tube 21 inputs plasma into the input chamber 13; (2) the plasma in the input cavity 13 flows into the circulating cavity 14 through the adsorption layer 11; (3) the plasma inside the circulating cavity 14 cannot directly enter the output cavity 15 under the isolation action of the isolation layer 12; (4) the external circulation input pipe 24 is externally connected with other plasma purification devices to purify the plasma in the circulation cavity 14; (5) the plasma purified by the external equipment flows into the output cavity 15 through the external circulation delivery pipe 25; (6) the finally separated and purified plasma flows into the storage bag 20 through the connection tube 22.
The above description is only for the preferred embodiment of the present invention, and is not intended to limit the present invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included within the protection scope of the present invention.
Claims (7)
1. A connection device for facilitating separation, purification and storage of plasma, comprising: a connecting bag (10), a first input pipe (21), a connecting pipe (22), an external circulation input pipe (24) and an external circulation output pipe (25);
an adsorption layer (11) and an isolation layer (12) are sequentially arranged inside the connecting bag (10), and the adsorption layer (11) and the isolation layer (12) sequentially divide the inside of the connecting bag (10) into an input cavity (13), a circulation cavity (14) and an output cavity (15);
the first input pipe (21) is communicated with the input cavity (13), the external circulation input pipe (24) is communicated with the circulation cavity (14), and the external circulation output pipe (25) and the connecting pipe (22) are respectively communicated with the output cavity (15).
2. The connection device for separating, purifying and storing plasma according to claim 1, wherein the connection bag (10) is sequentially detachably connected with a plurality of storage bags (20) through the connection tube (22), and the interior of the storage bags (20) is also provided with an adsorption layer (11).
3. The connection device for facilitating the separation, purification and storage of plasma according to claim 2, wherein the external circulation input tube (24) communicates with the bottom of the circulation chamber (14), the external circulation output tube (25) communicates with the top of the output chamber (15), and the capacity of the output chamber (15) is larger than the capacity of the circulation chamber (14) and the input chamber (13).
4. The connection device for facilitating the separation, purification and storage of plasma according to claim 3, wherein a flow regulator (26) is connected to the first input tube (21) and the connection tube (22), respectively.
5. The connection device for separating, purifying and storing plasma according to claim 4, wherein the first input tube (21), the connection tube (22), the external circulation input tube (24) and the external circulation output tube (25) are respectively connected with a liquid tube clamp (27).
6. The connection device for separating, purifying and storing plasma according to any of claims 1 to 5, wherein the top of the connection bag (10) is provided with a hanging hole (16).
7. The connection device for facilitating the separation, purification and storage of blood plasma according to claim 6, wherein the inside of the adsorption layer (11) is filled with activated carbon and resin carbon.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120202572.3U CN215133412U (en) | 2021-01-25 | 2021-01-25 | Connecting device convenient for plasma separation, purification and storage |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120202572.3U CN215133412U (en) | 2021-01-25 | 2021-01-25 | Connecting device convenient for plasma separation, purification and storage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215133412U true CN215133412U (en) | 2021-12-14 |
Family
ID=79407884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120202572.3U Expired - Fee Related CN215133412U (en) | 2021-01-25 | 2021-01-25 | Connecting device convenient for plasma separation, purification and storage |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215133412U (en) |
-
2021
- 2021-01-25 CN CN202120202572.3U patent/CN215133412U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211214 |