CN215087080U - Reaction kettle for adenine production - Google Patents
Reaction kettle for adenine production Download PDFInfo
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- CN215087080U CN215087080U CN202120618986.4U CN202120618986U CN215087080U CN 215087080 U CN215087080 U CN 215087080U CN 202120618986 U CN202120618986 U CN 202120618986U CN 215087080 U CN215087080 U CN 215087080U
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- reaction kettle
- kettle body
- adjusting plate
- reation kettle
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Abstract
The utility model provides a reation kettle is used in adenine production, includes the reation kettle body (1), (mixing) shaft (2), agitator motor (3) and a pair of unloading pipe (4), open at reation kettle body (1) top has a pair of feed opening, and open reation kettle body (1) bottom has the discharge gate, and unloading pipe (4) one end is passed the feed opening and is stretched into reation kettle body (1) in, and unloading pipe (4) that are located reation kettle body (1) are oval pipeline, and it has the multiunit discharge opening to open on the pipe wall of oval pipeline, the utility model discloses the advantage is: it is internal that each raw materials enters into reation kettle from the discharge opening of a pair of unloading pipe respectively, disperses the raw materials when reation kettle internal liquid flows, and oval pipeline can also play the liquid of reation kettle internal flow and block the dispersion effect in the unloading, through rotating oval pipeline, can also change the resistance size of unloading pipe to liquid, improves mixing efficiency.
Description
Technical Field
The utility model relates to a reation kettle technical field, concretely relates to reation kettle is used in adenine production.
Background
At present, tenofovir is an AIDS antiviral drug, and the production process comprises the steps of dissolving diethyl phosphite, paraformaldehyde and triethylamine in toluene, carrying out heating reaction in a reaction kettle, then cooling, adding tosyl chloride and triethylamine again to carry out low-temperature reaction to obtain a raw material of diethyl tosyloxymethyl phosphonate, then dissolving propylene glycol carbonate, adenine, diethyl tosyloxymethyl phosphonate and sodium hydroxide in dimethylformamide to react to obtain propyl adenine, dissolving propyl adenine in acetonitrile, adding bromotrimethylsilane to obtain a crude product of tenofovir, and carrying out water crystallization.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a reaction kettle for adenine production aiming at the defects.
The utility model comprises a reaction kettle body, a stirring shaft, a stirring motor and a pair of blanking pipes, wherein the reaction kettle body is provided with a jacket, one end of the bottom of the stirring shaft is provided with a stirrer, and the stirring motor is arranged at the top of the reaction kettle body and drives the stirrer to rotate in the reaction kettle body through the stirring shaft;
open at reation kettle body top has a pair of feed opening, open reation kettle body bottom has the discharge gate, it is internal that feed pipe one end passes the feed opening and stretches into reation kettle, the feed pipe that is located reation kettle is oval pipeline, and it has the multiunit discharge opening to open on the pipe wall of oval pipeline, feed pipe top one end rotatable coupling is on the feed opening of the reation kettle body, be equipped with angle adjusting plate on the reation kettle body that is located between a pair of feed pipe, be equipped with regulating plate installation axle on the reation kettle body, and the spiro union has the locking handle on the regulating plate installation axle, open at the angle adjusting plate middle part has the regulating plate installation axle to dodge the hole, angle adjusting plate movable mounting is on the regulating plate installation axle, and lock through the locking handle, the top one end of feed pipe is equipped with the swing arm, angle adjusting plate's both ends are respectively through connecting rod and the swing arm swing joint that corresponds.
The bottom in the reaction kettle body is provided with a stirring shaft mounting seat, and one end of the bottom of the stirring shaft is movably mounted on the stirring shaft mounting seat.
The stirring shaft in the reaction kettle body is rotatably connected with a shaft sleeve, the shaft sleeve is provided with a discharging pipe connecting rod, and one end of the bottom of each discharging pipe is movably connected with the discharging pipe connecting rod.
The stirrer is an anchor frame type stirrer.
The minor axis of the inner diameter of the oval tube has a length no greater than half the length of the major axis.
The utility model has the advantages that: it is internal that each raw materials enters into reation kettle from the discharge opening of a pair of unloading pipe respectively, disperses the raw materials when reation kettle internal liquid flows, and oval pipeline can also play the liquid of reation kettle internal flow and block the dispersion effect in the unloading, through rotating oval pipeline, can also change the resistance size of unloading pipe to liquid, improves mixing efficiency.
Description of the drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic view of the linkage structure at the top of a pair of blanking pipes.
Detailed Description
As shown in the attached drawings, the utility model comprises a reaction kettle body 1, a stirring shaft 2, a stirring motor 3 and a pair of discharging pipes 4, wherein a jacket 5 is arranged on the reaction kettle body 1, a stirrer 6 is arranged at one end of the bottom of the stirring shaft 2, the stirring motor 3 is arranged at the top of the reaction kettle body 1, and the stirrer 6 is driven by the stirring shaft 2 to rotate in the reaction kettle body 1;
the top of the reaction kettle body 1 is provided with a pair of feed openings, the bottom of the reaction kettle body 1 is provided with a discharge opening, one end of the feed pipe 4 passes through the feed openings and extends into the reaction kettle body 1, the feed pipe 4 positioned in the reaction kettle body 1 is an elliptical pipeline, a plurality of groups of discharge holes are arranged on the pipe wall of the oval pipeline, one end of the top of each discharge pipe 4 is rotatably connected on a discharge port of the reaction kettle body 1, an angle adjusting plate 8 is arranged on the reaction kettle body 1 between the pair of discharge pipes 4, an adjusting plate mounting shaft is arranged on the reaction kettle body 1, a locking handle 9 is screwed on the adjusting plate mounting shaft, an adjusting plate mounting shaft avoiding hole is arranged in the middle of the angle adjusting plate 8, the angle adjusting plate 8 is movably mounted on the adjusting plate mounting shaft, and is locked by a locking handle 9, one end of the top of the blanking tube 4 is provided with a swing arm 10, and two ends of an angle adjusting plate 8 are respectively movably connected with the corresponding swing arms 10 through connecting rods.
The bottom in the reaction kettle body 1 is provided with a stirring shaft mounting seat 11, and one end of the bottom of the stirring shaft 2 is movably mounted on the stirring shaft mounting seat 11.
The stirring shaft 2 in the reaction kettle body 1 is rotatably connected with a shaft sleeve 12, a feeding pipe connecting rod 13 is arranged on the shaft sleeve 12, and one end of the bottom of each feeding pipe 4 is movably connected with the feeding pipe connecting rod 13.
The stirrer 6 is an anchor frame stirrer.
The minor axis of the inner diameter of the oval tube has a length no greater than half the length of the major axis.
The working mode and principle are as follows: all raw materials enter organic solution in the reaction kettle body 1 from the pair of discharging pipes 4 in sequence, the stirrer 6 stirs the organic solution in the reaction kettle body 1, the organic solution brings out all raw materials in the discharging pipes 4 from a discharging hole when flowing, so that the organic solution is uniformly dispersed, meanwhile, the pair of discharging pipes 4 play a role in blocking liquid flowing in the reaction kettle body 1, the speed of the liquid rotating coaxially with the stirrer 6 in the reaction kettle body 1 is reduced, the dispersing speed and the stirring efficiency are improved, the resistance of the pair of discharging pipes 4 to flowing liquid can be adjusted according to needs, the discharging pipes 4 in the reaction kettle body 1 are oval pipes, the orientations of the oval pipes facing the flowing direction of the liquid are different, the resistance is also different, when in adjustment, the rotating angle adjusting plate 8, two ends of the angle adjusting plate 8 drive two swing arms 10 to synchronously through connecting rods respectively, the pair of discharging pipes 4 rotate a certain angle along the axis of the discharging pipes respectively, the blocking area of the discharging pipes for flowing liquid is changed, the resistance of the discharging pipes is the largest when the inner diameter long shaft surface of the oval pipe faces the flowing direction of the liquid, on the contrary, the resistance of the discharging pipes for flowing liquid is the smallest when the inner diameter short shaft surface of the oval pipe faces the flowing direction of the liquid, the liquid passing through the discharging pipes 4 passes through the discharging holes, the mixed liquid is dispersed, and the stirring efficiency is improved.
Claims (5)
1. A reaction kettle for adenine production is characterized by comprising a reaction kettle body (1), a stirring shaft (2), a stirring motor (3) and a pair of discharging pipes (4), wherein a jacket (5) is arranged on the reaction kettle body (1), a stirrer (6) is arranged at one end of the bottom of the stirring shaft (2), the stirring motor (3) is arranged at the top of the reaction kettle body (1), and the stirrer (6) is driven by the stirring shaft (2) to rotate in the reaction kettle body (1);
the top of the reaction kettle body (1) is provided with a pair of feed openings, the bottom of the reaction kettle body (1) is provided with a discharge opening, one end of the feed pipe (4) penetrates through the feed opening and extends into the reaction kettle body (1), the feed pipe (4) positioned in the reaction kettle body (1) is an oval pipeline, the pipe wall of the oval pipeline is provided with a plurality of groups of discharge openings, one end of the top of the feed pipe (4) is rotatably connected on the feed opening of the reaction kettle body (1), the reaction kettle body (1) positioned between the pair of feed pipes (4) is provided with an angle adjusting plate (8), the reaction kettle body (1) is provided with an adjusting plate mounting shaft, the adjusting plate mounting shaft is screwed with a locking handle (9), the middle part of the angle adjusting plate (8) is provided with an adjusting plate avoiding hole, the angle adjusting plate (8) is movably arranged on the adjusting plate mounting shaft and locked by the locking handle (9), one end of the top of the feed pipe (4) is provided with a swing arm (10), two ends of the angle adjusting plate (8) are respectively movably connected with the corresponding swing arms (10) through connecting rods.
2. The reaction kettle for producing adenine according to claim 1 wherein a stirring shaft mounting seat (11) is provided at the bottom of the reaction kettle body (1), and one end of the bottom of the stirring shaft (2) is movably mounted on the stirring shaft mounting seat (11).
3. The reaction kettle for adenine production as claimed in claim 1, wherein a shaft sleeve (12) is rotatably connected to the stirring shaft (2) in the reaction kettle body (1), a blanking pipe connecting rod (13) is arranged on the shaft sleeve (12), and one end of the bottom of the pair of blanking pipes (4) is movably connected with the blanking pipe connecting rod (13) respectively.
4. The reaction tank for producing adenine as claimed in claim 1, wherein the agitator (6) is an anchor frame agitator.
5. The reaction vessel for producing adenine as claimed in claim 1, wherein the minor axis length of the inner diameter of the oval tube is not more than half of the major axis length.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120618986.4U CN215087080U (en) | 2021-03-26 | 2021-03-26 | Reaction kettle for adenine production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120618986.4U CN215087080U (en) | 2021-03-26 | 2021-03-26 | Reaction kettle for adenine production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215087080U true CN215087080U (en) | 2021-12-10 |
Family
ID=79343566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120618986.4U Active CN215087080U (en) | 2021-03-26 | 2021-03-26 | Reaction kettle for adenine production |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215087080U (en) |
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2021
- 2021-03-26 CN CN202120618986.4U patent/CN215087080U/en active Active
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