CN215066121U - Solid tumor immune microenvironment detection and analysis device - Google Patents

Solid tumor immune microenvironment detection and analysis device Download PDF

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Publication number
CN215066121U
CN215066121U CN202121145424.9U CN202121145424U CN215066121U CN 215066121 U CN215066121 U CN 215066121U CN 202121145424 U CN202121145424 U CN 202121145424U CN 215066121 U CN215066121 U CN 215066121U
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China
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detection
groove
vertical plate
fixedly arranged
spectrum receiving
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CN202121145424.9U
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Chinese (zh)
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赵森林
李大卫
密玉帅
施德兵
冯亚光
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Fudan University Shanghai Cancer Center
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Fudan University Shanghai Cancer Center
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Abstract

The utility model aims to provide an entity tumour immunity microenvironment detection and analysis device, which comprises a base, a detection light source, a detection groove and a spectrum receiving component, wherein the detection light source, the detection groove and the spectrum receiving component are distributed from bottom to top, the detection groove is a transparent groove body, a vertical plate is fixed on one side of the base, the detection light source is fixedly arranged on the base, the detection groove is fixedly arranged on the vertical plate through a connecting rod, a supporting plate is longitudinally and slidably arranged on the vertical plate, the spectrum receiving component is fixedly arranged at the bottom of the supporting plate, so that the spectrum receiving component can move up and down on the vertical plate along with the supporting plate, the device also comprises a cleaning sealing cover, a rotating seat is fixedly arranged on the base, a rotating column is rotatably arranged on the rotating seat, the axial direction of the rotating column is vertical, and a driving device for driving the rotating column to rotate is arranged in the rotating seat, the side wall of the rotating column is fixedly provided with a support, and the support is longitudinally provided with a second sliding block in a sliding manner.

Description

Solid tumor immune microenvironment detection and analysis device
Technical Field
The utility model relates to a detection and analysis device specifically is a solid tumor immunity microenvironment detection and analysis device.
Background
When a tumor patient is diagnosed, the patient needs to be subjected to immunodetection, and an immunodetection and analysis instrument is various detection and analysis equipment established by taking immunoreaction specificity as a principle and is widely applied to the field of life science. An immunoassay analyzer is an analyzer for measuring specific molecules in samples such as body fluid, serum, plasma, whole blood, etc., and generally comprises the steps of sample introduction, mixing, temperature control, reaction, cleaning, display, detection and analysis, etc.
In the cleaning work of the immunity detection analysis instrument, a fluid sample is placed in a detection tank, the sample is analyzed through spectrum, in order to improve the detection accuracy, after each detection, the interior of the detection tank needs to be washed, and the sample in the detection tank needs to be cleaned for the next detection; to ensure the sensitivity of the assay, the desired washing effect is the most thorough washing and the least sample residue.
The existing immunoassay analyzer can not effectively clean dead corners when being cleaned, so that the immunoassay analyzer still has sample residues after the washing is finished, bacteria are easily generated after the washing, and the factors are not favorable for the detection accuracy.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an entity tumour immunity microenvironment detection analysis device to solve the problem that proposes in the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme:
a solid tumor immune microenvironment detection and analysis device comprises a base, a detection light source, a detection groove and a spectrum receiving assembly, wherein the detection light source, the detection groove and the spectrum receiving assembly are distributed from bottom to top, the detection groove is a transparent groove body, a vertical plate is fixed on one side of the base, the detection light source is fixedly arranged on the base, the detection groove is fixedly arranged on the vertical plate through a connecting rod, a supporting plate is longitudinally and slidably arranged on the vertical plate, the spectrum receiving assembly is fixedly arranged at the bottom of the supporting plate, so that the spectrum receiving assembly can move up and down on the vertical plate along with the supporting plate, the device also comprises a cleaning sealing cover, a rotating seat is fixedly arranged on the base, a rotating column is rotatably arranged on the rotating seat, the axial direction of the rotating column is vertical, a driving device for driving the rotating column to rotate is arranged in the rotating seat, and a support is fixedly arranged on the side wall of the rotating column, longitudinal sliding installs the second slider on the support, wash the sealed cowling through the linking arm with the second slider is connected, and the rotation plane that should wash the sealed cowling is located all the time between spectrum receiving assembly and the detection groove, and slide when the second slider extremely during the bottom of support, wash the sealed lock of sealed cowling and be in detect on the groove, wash the interior fixed mounting of sealed cowling and have the spray board of shower nozzle, the feed liquor pipe that sprays the board extends to outside the sealed cowling of washing.
As a further aspect of the present invention: the upper end face of the detection groove is provided with a sealing groove for embedding the cleaning sealing cover.
As a further aspect of the present invention: and the detection tank is provided with a waste liquid pipe with a valve.
As a further aspect of the present invention: the bottom of the detection groove is an inclined bottom surface which faces the waste liquid pipe and inclines downwards.
As a further aspect of the present invention: the vertical plate is provided with a sliding groove, a first sliding block is arranged in the sliding groove in a sliding mode, the supporting plate is fixedly connected with the first sliding block, a lead screw is rotatably arranged in the sliding groove, and one end of the lead screw is in transmission connection with a motor.
Compared with the prior art, the beneficial effects of the utility model are that:
the utility model has the advantages of simple structure, high durability and convenient use, through with spectrum dash receiver subassembly slidable mounting on the riser, and fixed mounting has the support on rotating the post, it installs on the support to wash the seal cover longitudinal sliding, and the rotation plane that washs the seal cover lies in all the time between test groove and the spectrum dash receiver subassembly, thereby can carry out position control to wasing the seal cover, and to the test groove pressure spray rinsing, wash the completion back, wash the seal cover and separate and to stepping down with the test groove, from not influencing the detection, further reduce the sample and remain, improve and detect the accuracy.
Drawings
FIG. 1 is a schematic structural diagram of a solid tumor immune microenvironment detection analysis device;
FIG. 2 is a schematic view of the cleaning sealing cover away from the detection tank in the solid tumor immune microenvironment detection analysis device;
in the figure: base 1, riser 2, detection light source 3, detection groove 4, waste liquid pipe 5, shower nozzle 6, spray plate 7, backup pad 8, washing sealed cowling 9, motor 10, linking arm 11, spectrum receiving plate subassembly 12, rotate seat 13, rotate post 14, support 15, second slider 16, spout 17, lead screw 18, first slider 19.
Detailed Description
The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, rather than all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without creative work belong to the protection scope of the present invention based on the embodiments of the present invention.
Referring to fig. 1-2, in an embodiment of the present invention, an apparatus for detecting and analyzing a solid tumor immune microenvironment includes a base 1, a detection light source 3, a detection tank 4 and a spectrum receiving assembly, wherein the detection light source 3, the detection tank 4 and the spectrum receiving assembly are distributed from bottom to top, a fluid sample (such as blood, body fluid, etc.) is contained in the detection tank 4, the detection tank 4 is a transparent tank, the detection light source 3 is irradiated from the lower side of the detection tank 4, the spectrum receiving assembly receives a spectrum transmitted through the sample and transmits the information to an analysis host for analysis and detection, thereby completing the immunoassay, the apparatus is basically the same as the prior art, a vertical plate 2 is fixed on one side of the base 1, the detection light source 3 is fixedly installed on the base 1, the detection tank 4 is fixedly installed on the vertical plate 2 through a connecting rod, a supporting plate 8 is longitudinally slidably installed on the vertical plate 2, the spectrum receiving assembly is fixedly arranged at the bottom of the supporting plate 8, so that the spectrum receiving assembly moves up and down on the vertical plate 2 along with the supporting plate 8, and the distance between the spectrum receiving assembly and the detection groove 4 is adjusted.
This entity tumour immunity microenvironment detection analytical equipment still includes washs sealed cowling 9, fixed mounting on the base 1 rotates seat 13, rotate on the seat 13 and rotate and install rotation post 14, this rotation post 14's axial is vertical direction, rotates and has drive rotation post 14 pivoted drive arrangement in the seat 13, and fixed mounting has support 15 on the lateral wall of rotation post 14, vertical slidable mounting has second slider 16 on the support 15, wash the sealed cowling pass through linking arm 11 with second slider 16 is connected, and the rotation plane that should wash sealed cowling 9 is located all the time between spectrum receiving assembly and the detection groove 4, and slide extremely as second slider 16 during the bottom of support 15, wash sealed cowling 9 sealed lock and be in detect on the groove 4. The cleaning sealing cover 9 is internally and fixedly provided with a spray plate 7 with a spray head 6, and a liquid inlet pipe of the spray plate 7 extends out of the cleaning sealing cover 9.
When needs wash detection tank 4, rotate to detection tank 4 directly over through rotating post 14 earlier through wasing sealed cowling 9, rethread second slider 16 lapse to drive and wash sealed cowling 9 lock on detecting tank 4, this upper end that detects tank 4 has the confession wash the seal groove of sealed cowling 9 embedding, feed liquor pipe and outside water tank (not shown in the figure) are connected, and go into the antiseptic solution pump in the water tank and spray plate 7 in and to detecting tank 4 spray rinsing, thereby accomplish the washing operation, the waste liquid that the washing produced is discharged by the waste liquid pipe 5 that has the valve on detecting tank 4. In order to completely discharge the waste liquid in the detection tank 4, the bottom of the detection tank 4 is an inclined bottom surface inclined downward toward the waste liquid pipe 5.
In this embodiment, specifically, a sliding groove 17 is formed in the vertical plate 2, a first sliding block 19 is slidably mounted in the sliding groove 17, the supporting plate 8 is fixedly connected to the first sliding block 19, a screw rod 18 is rotatably mounted in the sliding groove 17, and one end of the screw rod 18 is in transmission connection with the motor 10. The second slider 16 is driven in the same manner as the first slider 19.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.

Claims (5)

1. The utility model provides an entity tumour immunity microenvironment detection analysis device, includes the base, detects the light source, detects groove and spectrum receiving element, detect the light source, detect groove and spectrum receiving element and distribute from bottom to top, detect the groove and be transparent cell body, its characterized in that: a vertical plate is fixed on one side of the base, the detection light source is fixedly arranged on the base, the detection groove is fixedly arranged on the vertical plate through a connecting rod, a supporting plate is longitudinally and slidably arranged on the vertical plate, the spectrum receiving assembly is fixedly arranged at the bottom of the supporting plate so as to realize the up-and-down movement of the spectrum receiving assembly on the vertical plate along with the supporting plate, the detection device further comprises a cleaning sealing cover, a rotating seat is fixedly arranged on the base, a rotating column is rotatably arranged on the rotating seat, the axial direction of the rotating column is vertical, a driving device for driving the rotating column to rotate is arranged in the rotating seat, a support is fixedly arranged on the side wall of the rotating column, a second sliding block is longitudinally and slidably arranged on the support, the cleaning sealing cover is connected with the second sliding block through a connecting arm, and the rotating plane of the cleaning sealing cover is always positioned between the spectrum receiving assembly and the detection groove, and when the second slider slides to when the lower extreme of support, wash the sealed lock of sealed cowling and be in detect on the groove, wash the interior fixed mounting of sealed cowling and have the spray board of shower nozzle, the feed liquor pipe of spray board extends to outside the sealed cowling of washing.
2. The solid tumor immune microenvironment detection and analysis device of claim 1, wherein: the upper end face of the detection groove is provided with a sealing groove for embedding the cleaning sealing cover.
3. The solid tumor immune microenvironment detection and analysis device of claim 1, wherein: and the detection tank is provided with a waste liquid pipe with a valve.
4. The solid tumor immune microenvironment detection and analysis device of claim 3, wherein: the bottom of the detection groove is an inclined bottom surface which faces the waste liquid pipe and inclines downwards.
5. The solid tumor immune microenvironment detection and analysis device of claim 1, wherein: the vertical plate is provided with a sliding groove, a first sliding block is arranged in the sliding groove in a sliding mode, the supporting plate is fixedly connected with the first sliding block, a lead screw is rotatably arranged in the sliding groove, and one end of the lead screw is in transmission connection with a motor.
CN202121145424.9U 2021-05-26 2021-05-26 Solid tumor immune microenvironment detection and analysis device Active CN215066121U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202121145424.9U CN215066121U (en) 2021-05-26 2021-05-26 Solid tumor immune microenvironment detection and analysis device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121145424.9U CN215066121U (en) 2021-05-26 2021-05-26 Solid tumor immune microenvironment detection and analysis device

Publications (1)

Publication Number Publication Date
CN215066121U true CN215066121U (en) 2021-12-07

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Application Number Title Priority Date Filing Date
CN202121145424.9U Active CN215066121U (en) 2021-05-26 2021-05-26 Solid tumor immune microenvironment detection and analysis device

Country Status (1)

Country Link
CN (1) CN215066121U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115598364A (en) * 2022-12-15 2023-01-13 广州仁恒医药科技股份有限公司(Cn) Tumor immune microenvironment detection and analysis device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115598364A (en) * 2022-12-15 2023-01-13 广州仁恒医药科技股份有限公司(Cn) Tumor immune microenvironment detection and analysis device
CN115598364B (en) * 2022-12-15 2023-03-10 广州仁恒医药科技股份有限公司 Tumor immune microenvironment detection and analysis device

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