CN215026210U

CN215026210U - High-pressure liquid chromatographic column sieve plate

Info

Publication number: CN215026210U
Application number: CN202121331723.1U
Authority: CN
Inventors: 魏少勇; 禹飞乐; 刘柏华; 杨薇; 曾义建
Original assignee: Guangzhou Flm Scientific Instrument Co ltd
Current assignee: Guangzhou Flm Scientific Instrument Co ltd
Priority date: 2021-06-15
Filing date: 2021-06-15
Publication date: 2021-12-07
Anticipated expiration: 2031-06-15

Abstract

The utility model discloses a high-pressure liquid chromatography column sieve plate, which comprises a fixed frame plate, wherein the fixed frame plate is erected at the top of an experiment table, a support rod is welded at the bottom of the fixed frame plate, a circular groove is formed in the top of the fixed frame plate, a limiting clamping groove is formed in the top of the fixed frame plate, and a rubber pad is fixed on the inner wall of the limiting clamping groove; the column tube is erected and installed on the experiment table through the fixing frame plate, and a chromatographic column sieve plate body is arranged inside the column tube. Utilize the bracing piece to erect the fixed frame plate level and fix on the laboratory bench, the outer wall of column tube is provided with spacing pothook, spacing pothook and spacing draw-in groove phase-match, can fix the column tube block on the fixed frame plate, through the design of fixed frame plate, be equipped with stable support fixed knot in the column tube outside, be provided with and maintain the horizontally structure of sieve, can guarantee that chromatographic column tube remains vertical state throughout when using, difficult emergence slope to avoided the sieve to lead to damaging because the slope.

Description

High-pressure liquid chromatographic column sieve plate

Technical Field

The utility model relates to a chromatographic column technical field specifically is a high pressure liquid chromatography column sieve.

Background

High performance liquid chromatography, also known as high pressure liquid chromatography, high speed liquid chromatography, high resolution liquid chromatography, modern column chromatography and the like, is an important branch of chromatography, and takes liquid as a mobile phase, adopts a high pressure infusion system, pumps the mobile phase such as single solvents with different polarities or mixed solvents with different proportions, buffer solution and the like into a chromatographic column filled with a stationary phase, and after all components in the column are separated, the mobile phase enters a detector for detection or further collection, thereby realizing analysis or separation of a sample, but the existing high pressure liquid chromatography column sieve plate has certain defects, for example, a high pressure liquid chromatography column sieve plate with the application number of 202020646203.9, a structure for maintaining the sieve plate in a horizontal state is not arranged, a column tube of the chromatographic column can not be always kept in a vertical state when in use, once the chromatographic column sieve plate is inclined when in use, the damage to the sieve plate is large, can cause the chromatographic column to use even when serious, be unfavorable for the long-term use of chromatographic column, in addition, the sieve does not be provided with protection architecture, and the solvent that needs to detect can't permeate the sieve from the assigned position, and certain error probably appears in the testing result of sieve.

Aiming at the problems, innovative design is urgently needed on the basis of the original sieve plate structure of the high-pressure liquid chromatography column.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a high pressure liquid chromatography column sieve to the column casing that proposes in solving above-mentioned background art does not set up and maintains the horizontally structure of sieve, can't guarantee the chromatographic column when using remains vertical state throughout, in case the chromatographic column sieve inclines when using, damage to the sieve is great, can cause the unable use of chromatographic column even when serious, the sieve is not provided with protective structure, the solvent that needs to detect can't follow the assigned position infiltration sieve, the problem of certain error probably appears in the testing result of sieve.

In order to achieve the above object, the utility model provides a following technical scheme: a high pressure liquid chromatography column sieve plate comprising:

the fixing frame plate is erected at the top of the experiment table, a support rod is welded at the bottom of the fixing frame plate, a circular groove is formed in the top of the fixing frame plate, a limiting clamping groove is formed in the top of the fixing frame plate, and a rubber pad is fixed on the inner wall of the limiting clamping groove;

the column tube is erected and installed on the experiment table through the fixed frame plate, a chromatographic column sieve plate body is arranged inside the column tube, and the outer wall of the column tube is fixedly connected with a limiting clamping hook;

the control valve is arranged on the outer wall of the column tube and is positioned right below the fixed frame plate;

and the pressing cap is arranged at the top of the column tube and is positioned right above the fixed frame plate, a sealing ring is fixedly arranged on the outer wall of the pressing cap, and the sealing ring is positioned between the column tube and the pressing cap.

Preferably, the bottom of the fixed frame plate is connected with the top end of the supporting rod in a welding mode, the welding positions of the supporting rod are arranged at the four corners of the bottom of the fixed frame plate, and the fixed frame plate and the supporting rod form an integrated structure.

Preferably, the circular groove is located the top central point of fixed frame plate and puts, and evenly is provided with spacing draw-in groove around the circular groove, and the quantity of spacing draw-in groove and spacing pothook is four, and spacing draw-in groove and the setting of spacing pothook one-to-one.

Preferably, the limiting clamping hook and the fixed frame plate form a clamping structure through the limiting clamping groove and the rubber pad, the inner surface of the rubber pad is attached to the outer surface of the limiting clamping hook, and the inner size of the rubber pad is completely matched with the outer size of the limiting clamping hook.

Preferably, the bottom end of the column tube penetrates through the top of the fixing frame plate and extends to the bottom of the fixing frame plate, the column tube penetrates through the column tube through the circular groove, and the outer wall of the column tube is completely attached to the inner wall of the circular groove.

Preferably, chromatographic column sieve plate body is including fixed frame, sieve composite bed, protection disk and protection disk, and sieve composite bed fixed mounting has the inner wall of fixed frame to the top of sieve composite bed is fixed with the protection disk, and the top of protection disk has been seted up moreover and has been annotated the liquid round hole.

Compared with the prior art, the utility model provides a high pressure liquid chromatography column sieve has following advantage:

1. the fixing frame plate is horizontally erected and fixed on the experiment table by utilizing the supporting rod, the outer wall of the column tube is provided with the limiting clamping hook, the limiting clamping hook is matched with the limiting clamping groove, the column tube can be clamped and fixed on the fixing frame plate, a stable supporting and fixing structure is arranged outside the column tube through the design of the fixing frame plate, and a structure for maintaining the horizontal state of the sieve plate is arranged, so that the column tube of the chromatographic column can be ensured to be always kept in a vertical state when in use, and is not easy to incline, thereby avoiding the damage of the sieve plate caused by the inclination, and being beneficial to ensuring the long-term use of the chromatographic column;

2. be provided with the protection disk at the top of sieve composite bed, the solution that needs to detect can only follow and annotate liquid round hole flow direction sieve composite bed, is provided with fixed frame at the lateral wall of sieve composite bed simultaneously, has played the effect of spacing protection to the sieve composite bed, and the sieve of this chromatographic column is provided with protective structure, and the solvent that needs to detect can follow assigned position infiltration sieve, and the testing result of sieve is difficult for appearing the error.

Drawings

FIG. 1 is a schematic front sectional view of the present invention;

FIG. 2 is a schematic front view of the present invention;

FIG. 3 is an enlarged schematic view of the structure at A of FIG. 1 according to the present invention;

fig. 4 is a schematic view of the structural connection between the fixing frame plate and the support rod of the present invention;

fig. 5 is a schematic view of the cross-sectional structure of the chromatographic column sieve plate body of the present invention.

In the figure: 1. fixing the frame plate; 2. a support bar; 3. a circular groove; 4. a limiting clamping groove; 5. a rubber pad; 6. a column tube; 7. a chromatographic column sieve plate body; 701. a fixing frame; 702. a sieve plate composite layer; 703. protecting the wafer; 704. injecting a round hole; 8. a limit hook; 9. controlling the movable valve; 10. pressing the cap; 11. and sealing the ring.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-5, the present invention provides a technical solution: a high pressure liquid chromatography column sieve plate comprising: a fixed frame plate 1, a support rod 2, a circular groove 3, a limit clamping groove 4, a rubber pad 5, a column tube 6, a chromatographic column sieve plate body 7, a fixed frame 701, a sieve plate composite layer 702, a protection wafer 703, a liquid injection circular hole 704, a limit clamping hook 8, a control movable valve 9, a press cap 10 and a sealing ring 11,

the device comprises a fixed frame plate 1, a support rod 2, a circular groove 3, a limiting clamping groove 4 and a rubber pad 5, wherein the fixed frame plate 1 is erected at the top of the experiment table, the support rod 2 is welded at the bottom of the fixed frame plate 1, the circular groove 3 is formed in the top of the fixed frame plate 1, the limiting clamping groove 4 is formed in the top of the fixed frame plate 1, and the inner wall of the limiting clamping groove 4 is fixed with the rubber pad 5;

the column tube 6 is erected and installed on the experiment table through the fixed frame plate 1, a chromatographic column sieve plate body 7 is arranged inside the column tube 6, and the outer wall of the column tube 6 is fixedly connected with a limiting clamping hook 8;

the control valve 9 is arranged on the outer wall of the column tube 6, and the control valve 9 is positioned right below the fixed frame plate 1;

and the pressing cap 10 is installed at the top of the column tube 6, the pressing cap 10 is positioned right above the fixing frame plate 1, the sealing ring 11 is fixedly installed on the outer wall of the pressing cap 10, and the sealing ring 11 is positioned between the column tube 6 and the pressing cap 10.

Specifically, as shown in fig. 1 and 4, the bottom of the fixing frame plate 1 is connected with the top end of the support rod 2 in a welding manner, the welding positions of the support rod 2 are arranged at four corners of the bottom of the fixing frame plate 1, and the fixing frame plate 1 and the support rod 2 form an integrated structure, so that the fixing frame plate 1 and the support rod 2 are connected more tightly and can stand on the experiment table more stably due to the integrated structure;

specifically, as shown in fig. 1, 2 and 4, the circular groove 3 is located at the center of the top of the fixed frame plate 1, the four sides of the circular groove 3 are uniformly provided with the four limiting clamping grooves 4, the number of the limiting clamping grooves 4 and the number of the limiting clamping hooks 8 are four, the limiting clamping grooves 4 and the limiting clamping hooks 8 are arranged in a one-to-one correspondence manner, and the column tube 6 can be clamped in the circular groove 3 of the fixed frame plate 1 more stably through the arranged limiting clamping grooves 4 and the limiting clamping hooks 8;

specifically, as shown in fig. 1 and 3, the limiting hook 8 and the fixed frame plate 1 form a clamping structure through the limiting clamping groove 4 and the rubber pad 5, the inner surface of the rubber pad 5 is attached to the outer surface of the limiting hook 8, the inner size of the rubber pad 5 is completely matched with the outer size of the limiting hook 8, and the design of the rubber pad 5 fills the gap between the limiting hook 8 and the limiting clamping groove 4, so that the clamping of the limiting hook 8 is more tight;

specifically, as shown in fig. 1, the bottom end of the column tube 6 penetrates through the top of the fixing frame plate 1 and extends to the bottom of the fixing frame plate 1, the column tube 6 penetrates through the column tube 6 through the circular groove 3, the outer wall of the column tube 6 is completely attached to the inner wall of the circular groove 3, and the column tube 6 can penetrate through and be clamped in the fixing frame plate 1 through the circular groove 3;

specifically, as shown in fig. 5, the chromatographic column sieve plate body 7 includes a fixing frame 701, a sieve plate composite layer 702, a protection wafer 703 and a protection wafer 703, the sieve plate composite layer 702 is fixedly provided with an inner wall of the fixing frame 701, the protection wafer 703 is fixed at the top of the sieve plate composite layer 702, a liquid injection round hole 704 is formed in the top of the protection wafer 703, and liquid to be detected can be dispersed from the center of the top of the sieve plate composite layer 702 through the protection wafer 703.

The working principle is as follows: when the high-pressure liquid chromatography column sieve plate is used, according to the figures 1, 2, 3 and 4, firstly, a fixed frame plate 1 is erected and placed on an experiment table through a support rod 2, the surface of the fixed frame plate 1 is kept in a horizontal state, then a column tube 6 penetrates through a circular groove 3 formed in the top of the fixed frame plate 1 and is clamped, a limiting clamping hook 8 is inserted into the limiting clamping groove 4, a rubber pad 5 is arranged on the inner wall of the limiting clamping groove 4 and fills a gap between the limiting clamping hook 8 and the limiting clamping groove 4, so that the clamping of the limiting clamping hook 8 is tighter, the column tube 6 is clamped and fixed on the fixed frame plate 1, a vertical state is kept, a solution to be detected enters the column tube 6 from the top of the column tube 6 and permeates downwards, and the stability of the pressure inside the column tube 6 is ensured through the design of a pressing cap 10 and a sealing ring 11;

according to fig. 1 and 5, a protection wafer 703 is arranged at the top of the sieve plate composite layer 702, so that a solution to be detected can only flow to the sieve plate composite layer 702 from the liquid injection circular hole 704, and meanwhile, the sieve plate composite layer 702 is limited and fixed in the fixing frame 701, the fixing frame 701 plays a role in limiting and protecting the sieve plate composite layer 702, and the sieve plate composite layer 702 can be prevented from deforming under pressure.

Those not described in detail in this specification are within the skill of the art. Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A high pressure liquid chromatography column sieve plate, comprising:

2. The high pressure liquid chromatography column sieve plate of claim 1, wherein: the bottom of the fixed frame plate is connected with the top end of the supporting rod in a welding mode, the welding positions of the supporting rod are arranged at the four corners of the bottom of the fixed frame plate, and the fixed frame plate and the supporting rod form an integrated structure.

3. The high pressure liquid chromatography column sieve plate of claim 1, wherein: the circular groove is located the top central point of fixed frame plate and puts, and evenly is provided with spacing draw-in groove around the circular groove, and the quantity of spacing draw-in groove and spacing pothook is four, and spacing draw-in groove and the setting of spacing pothook one-to-one.

4. The high pressure liquid chromatography column sieve plate of claim 1, wherein: the limiting clamping hook and the fixed frame plate form a clamping structure through the limiting clamping groove and the rubber pad, the inner surface of the rubber pad is attached to the outer surface of the limiting clamping hook, and the inner size of the rubber pad is completely matched with the outer size of the limiting clamping hook.

5. The high pressure liquid chromatography column sieve plate of claim 1, wherein: the bottom of pillar pipe runs through the top of fixed frame board and extends to the bottom of fixed frame board, and the pillar pipe runs through the pillar pipe through the circular recess, and the outer wall of pillar pipe and the inner wall of circular recess laminate completely.

6. The high pressure liquid chromatography column sieve plate of claim 1, wherein: chromatographic column sieve body is including fixed frame, sieve composite bed, protection disk and protection disk, and sieve composite bed fixed mounting has the inner wall of fixed frame to the top of sieve composite bed is fixed with the protection disk, and the top of protection disk has seted up moreover and has annotated the liquid round hole.