CN215012479U - Rat chronic temperature and stress experimental device capable of semi-automatically replacing padding - Google Patents
Rat chronic temperature and stress experimental device capable of semi-automatically replacing padding Download PDFInfo
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- CN215012479U CN215012479U CN202120350606.3U CN202120350606U CN215012479U CN 215012479 U CN215012479 U CN 215012479U CN 202120350606 U CN202120350606 U CN 202120350606U CN 215012479 U CN215012479 U CN 215012479U
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- bedding
- squirrel cage
- side plate
- padding
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- 230000001684 chronic effect Effects 0.000 title claims abstract description 16
- 241000700159 Rattus Species 0.000 claims abstract description 44
- 241000555745 Sciuridae Species 0.000 claims abstract description 28
- 239000000463 material Substances 0.000 claims abstract description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 239000007921 spray Substances 0.000 claims description 10
- 238000005192 partition Methods 0.000 claims description 4
- 230000001678 irradiating effect Effects 0.000 claims description 3
- 238000005253 cladding Methods 0.000 claims description 2
- 230000005611 electricity Effects 0.000 claims description 2
- 230000037326 chronic stress Effects 0.000 claims 7
- 230000035882 stress Effects 0.000 claims 3
- 238000002474 experimental method Methods 0.000 abstract description 12
- 230000008859 change Effects 0.000 abstract description 8
- 230000000638 stimulation Effects 0.000 description 9
- 238000000034 method Methods 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 229910000831 Steel Inorganic materials 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
- 238000013508 migration Methods 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 230000004938 stress stimulation Effects 0.000 description 2
- 208000034656 Contusions Diseases 0.000 description 1
- 230000009519 contusion Effects 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000009182 swimming Effects 0.000 description 1
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Abstract
The utility model relates to a chronic mild stress experimental facilities, the rat chronic temperature that specifically says so can trade bedding and padding partly with stress experimental apparatus, including the squirrel cage that can feed many rats, one side of squirrel cage is provided with the district compartment, install telescopic cylinder in the district compartment, this telescopic cylinder drives the diapire slope of squirrel cage. The utility model discloses a telescopic cylinder drive diapire rotates, can make the diapire slope to realize the mild stress experiment of rat. When the experiment device is adopted, a worker only needs to start the telescopic air cylinder, and the experiment efficiency is greatly improved. And simultaneously, the utility model discloses still adopt push-and-pull cylinder and work or material rest to realize the semi-automatic change of bedding and padding, the staff only needs to start push-and-pull cylinder and pulls out the work or material rest, then more renew the bedding and padding, promotes the work or material rest again and resets and can accomplish the change of bedding and padding, has further improved experimental efficiency.
Description
Technical Field
The utility model relates to a chronic mild stress experimental facilities, the chronic mild stress experimental apparatus of rat that specifically says so can semi-automatically trade bedding and padding.
Background
The chronic mild stress model refers to the induction of an animal into a state of depression by using chronic, mild and unpredictable stress stimuli. The chronic mild stress model is considered as an animal model closest to depression caused by stress and contusion which people encounter in daily life for a long time, and is widely applied to the research of depression as an effective animal model. For example, the rats are raised in a mild stress stimulation environment, wherein the mild stress stimulation environment comprises foot electric shock, stroboscopic stimulation, overnight illumination, water deprivation, fasting, cage tilting, cage shaking, day and night reversing, forced swimming, noise stimulation, moist dressing, crowded raising and the like, the stimulation is randomly selected to be performed every day, the stimulation of the same kind is not continuously used within two days, after modeling for a certain time (generally 4 weeks), the animals show a certain similarity in horizontal activity and vertical activity times, the sugar water consumption is reduced, and the clinical common mental movement state change and interest loss of depression patients have certain similarity, and the success or failure of modeling can be confirmed after corresponding detection.
At present, a rat chronic mild stress model is that an experimenter artificially raises a rat by adopting a common rat cage, selects one stimulation every day and applies the stimulation to an animal body by the experimenter, and some stimulations need special tools, such as foot sole electric shock, stroboscopic stimulation, day and night inversion, noise stimulation and the like, which are troublesome in operation and take much time; and the experimental personnel need to replace the padding polluted by the rats every 3-5 days, the time spent on replacing the padding every time is long, and if the number of the rats is large, the time and the energy spent by the working personnel are too much, so the experimental efficiency is influenced.
SUMMERY OF THE UTILITY MODEL
To the technical problem, the utility model provides an efficiency of the experiment can be improved rat chronic temperature and stress experimental apparatus of semi-automatic pad changing.
The utility model provides a technical scheme that above-mentioned technical problem adopted does: the utility model provides a can change chronic temperature of rat and stress experimental apparatus of bedding and padding semi-automatically, is including the squirrel cage that can feed many rats, one side of squirrel cage is provided with the district compartment, install telescopic cylinder in the district compartment, this telescopic cylinder drives the diapire slope of squirrel cage.
Preferably, one side of the bottom wall of the squirrel cage is hinged to the left side plate of the other side of the squirrel cage, the other side of the bottom wall extends into the partition and is connected with the telescopic rod of the telescopic cylinder, and the telescopic cylinder drives the other side of the bottom wall to rotate through the telescopic rod.
Preferably, the right side plate on one side of the squirrel cage is fixedly connected with the bottom wall, a strip-shaped hole is formed in the cover plate of the squirrel cage, and the right side plate penetrates through the strip-shaped hole.
Preferably, a bottom plate fixedly connected with the left side plate is arranged on the lower side of the bottom wall, a side door is vertically and fixedly connected onto the bottom plate, and the cover plate, the right side plate, the bottom plate and the side door are coated into the partition.
Preferably, the side door comprises a door frame fixedly connected with the bottom plate, and a movable door is mounted on the door frame.
Preferably, a material rack capable of placing padding materials is arranged on the bottom wall, an opening is formed in the right side plate, and the material rack penetrates through the opening and can move left and right.
Preferably, the material rest comprises a frame body capable of placing padding and a side plate vertically connected with the frame body, the frame body is pushed to the bottom wall from the opening through the side plate, the side plate is tightly attached to the right side plate, and the side plate is driven to move through a push-pull air cylinder arranged in the area compartment.
Preferably, the bottom wall adopts a multilayer conductive steel wire mesh structure, and the bottom wall is electrically connected with a power supply arranged in the partition.
Preferably, a light source capable of irradiating rats in the mouse cage is mounted on the right side plate, and the power supply supplies power to the light source.
Preferably, the cover plate is provided with a feeding groove capable of storing food and water, spray heads are arranged on two sides of the feeding groove, and an external water source can spray water to the rats in the squirrel cage through the spray heads.
According to the technical scheme provided by the utility model, the utility model discloses a telescopic cylinder drive diapire rotates, can make the diapire slope to realize the mild stress experiment of rat. When the experiment device is adopted, a worker only needs to start the telescopic air cylinder, and the experiment efficiency is greatly improved. And simultaneously, the utility model discloses still adopt push-and-pull cylinder and work or material rest to realize the semi-automatic change of bedding and padding, the staff only needs to start push-and-pull cylinder and pulls out the work or material rest, then more renew the bedding and padding, promotes the work or material rest again and resets and can accomplish the change of bedding and padding, has further improved experimental efficiency.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic structural diagram of the material shelf of the present invention.
Detailed Description
The present invention will be described in detail with reference to fig. 1 and 2, and the exemplary embodiments and descriptions of the present invention are provided to explain the present invention, but not to limit the present invention.
The utility model provides a can trade chronic temperature of rat and stress experimental apparatus of bedding and padding semi-automatically, it is including the squirrel cage 1 that can feed many rats, one side of squirrel cage is provided with district compartment 2, install telescopic cylinder 3 in the district compartment, this telescopic cylinder drives the diapire 17 slope of squirrel cage makes the rat on the diapire stand on the plane of slope to realize stress experiment. Specifically, one side of the bottom wall of the squirrel cage is hinged with a left side plate 11 on the other side of the squirrel cage, for example, a rotating shaft can be arranged on the left side plate and hinged with the bottom wall; this diapire opposite side stretches into district compartment with telescopic cylinder's telescopic link is connected, and this telescopic cylinder passes through the telescopic link drive the diapire opposite side rotates to the slope form is rotated to the assurance diapire. In the implementation process, the right side plate 12 of one side of the squirrel cage is fixedly connected with the bottom wall, so that the squirrel cage can rotate along with the bottom wall, the cover plate 13 of the squirrel cage is provided with the strip-shaped hole 14, the right side plate penetrates through the strip-shaped hole, and the strip-shaped hole provides a rotating space for the right side plate.
The utility model discloses a diapire downside be equipped with left side board fixed connection's bottom plate 15 can set up the support bar on the bottom plate and support the diapire, vertical fixedly connected with side door 21 on the bottom plate, apron, right side board, bottom plate and side door cladding become the district compartment, of course, district compartment and squirrel cage have front bezel and back plate (not shown in the figure) in addition to constitute six three-dimensional enclosure spaces. The utility model separates the compartment from the rat cage, on one hand, the independence of the rat cage can be ensured, and the experiment is convenient; and a driving device, a power supply device and the like are conveniently arranged in the other part of the interval, and interference is avoided. In practice, the side door 21 includes a door frame 22 fixedly connected to the bottom plate, and a movable door 23 is installed on the door frame, and when the padding needs to be repaired or replaced, the movable door can be opened. Especially when the padding is replaced, after the movable door is opened, the material rack can move to the outside of the movable door, so that the material rack can be completely pulled out.
Preferably, a material rack 4 capable of containing the padding 6 is arranged on the bottom wall, an opening 18 is formed in the right side plate, the material rack penetrates through the opening and can move left and right, and therefore the padding on the material rack can be replaced. Specifically, the material rest 4 comprises a frame body 41 capable of placing padding materials and a side plate 42 vertically connected with the frame body, the frame body is pushed to the bottom wall from the opening through the side plate, the side plate is tightly attached to the right side plate, and the side plate is driven to move through a push-pull air cylinder 5 arranged in the area compartment. In the implementation process, push-and-pull cylinder bottom articulates on the right side board, can rotate along with the right side board, can not interfere the rotation of diapire, and articulated push-and-pull cylinder passes through link mechanism drive sideboard horizontal migration, if set up the support on the diapire, be equipped with the horizon bar on the support, and support this horizon bar, horizon bar one end is connected with the sideboard, the other end is articulated with the push-and-pull cylinder top, because the equal swing joint in push-and-pull cylinder both ends, consequently at the in-process that push-and-pull cylinder extends or shortens, the horizon bar keeps horizontal migration under the restraint of support. The design can ensure that the material rest is completely pulled out, and the padding can be conveniently replaced. When need changing the bedding and padding, can open the dodge gate, start push-and-pull cylinder pulling sideboard in the interval from the district, the framework with pollute the bedding and padding right side shift in the lump, then change new bedding and padding, restart push-and-pull cylinder promotes the sideboard, from this the framework with new bedding and padding left side shift in the lump to arranging in on the diapire to realized semi-automatic change bedding and padding, improved experimental efficiency greatly.
The utility model discloses a diapire adopts the electrically conductive wire net structure of multilayer, the diapire is connected with the power 7 electricity that sets up in the interval. The multi-layer conductive steel wire mesh structure has stronger supporting force on one hand and can support rats; on the other hand, after being electrified, the electric shock can be carried out on the rat in the mouse cage, so that the purpose of stress experiment is achieved. In practice, the rack is pulled out with the padding, the rat is allowed to stand on the bottom wall, and then the bottom wall is energized to shock the rat. Preferably, the right side plate is provided with a light source 8 capable of irradiating rats in the mouse cage, and the power supply supplies power to the light source so as to irradiate the rats in the mouse cage. In the implementation process, a feeding groove 16 capable of storing food and water is arranged on the cover plate, so that rats can be conveniently fed; spray nozzles 9 are arranged on two sides of the feeding trough, and an external water source can spray water to rats in the mouse cage through the spray nozzles, so that a water spray stress experiment is carried out on the rats. The device of the utility model integrates stress experiments such as water spraying, illumination, electric shock, inclination and the like, and has the advantages of various functions and high experimental efficiency; and the use is convenient, and the structure is simple.
Claims (10)
1. The utility model provides a chronic mild stress experimental apparatus of rat that can semi-automatically trade bedding, includes the squirrel cage that can feed many rats, its characterized in that: one side of squirrel cage is provided with the district compartment, install telescopic cylinder in the district compartment, this telescopic cylinder drives the diapire slope of squirrel cage.
2. A semi-automatic bedding-changing chronic stress and temperature testing apparatus for rats according to claim 1, wherein: one side of the bottom wall of the squirrel cage is hinged to the left side plate of the other side of the squirrel cage, the other side of the bottom wall extends into the partition and is connected with the telescopic rod of the telescopic cylinder, and the telescopic cylinder drives the other side of the bottom wall to rotate through the telescopic rod.
3. A semi-automatic bedding-changing chronic stress and temperature testing apparatus for rats according to claim 2, wherein: the right side plate of one side of the squirrel cage is fixedly connected with the bottom wall, a strip-shaped hole is formed in the cover plate of the squirrel cage, and the right side plate penetrates through the strip-shaped hole.
4. A semi-automatic bedding-changing chronic stress and temperature testing apparatus for rats according to claim 3, wherein: the bottom wall lower side be equipped with left side board fixed connection's bottom plate, vertical fixedly connected with limit door on the bottom plate, apron, right side board, bottom plate and limit door cladding become the district compartment.
5. A semi-automatic bedding changeable rat chronic mild stress experimental facility as claimed in claim 4, wherein: the side door comprises a door frame fixedly connected with the bottom plate, and a movable door is installed on the door frame.
6. A semi-automatic bedding changeable rat chronic stress and temperature experimental facility according to any one of claims 3 to 5, characterized in that: the bottom wall is provided with a material rack for placing padding, the right side plate is provided with an opening, and the material rack penetrates through the opening and can move left and right.
7. A semi-automatic bedding changeable rat chronic mild stress experimental facility as claimed in claim 6, wherein: the material rack comprises a frame body capable of containing padding and a side plate vertically connected with the frame body, the frame body is pushed to the bottom wall through the side plate from the opening, the side plate is tightly attached to the right side plate, and the side plate is driven to move through a push-pull air cylinder arranged in the area compartment.
8. A semi-automatic bedding-changing chronic stress and temperature testing apparatus for rats according to claim 7, wherein: the diapire adopts the electrically conductive wire net structure of multilayer, the diapire is connected with the power electricity that sets up in the district compartment.
9. A semi-automatic bedding-changing chronic stress and temperature testing apparatus for rats according to claim 8, wherein: the right side plate is provided with a light source capable of irradiating rats in the mouse cage, and the power supply supplies power to the light source.
10. A semi-automatic bedding-changing chronic stress and temperature testing apparatus for rats according to claim 3, wherein: the cover plate is provided with a feeding groove capable of storing food and water, spray heads are arranged on two sides of the feeding groove, and an external water source can spray water to rats in the squirrel cage through the spray heads.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120350606.3U CN215012479U (en) | 2021-02-08 | 2021-02-08 | Rat chronic temperature and stress experimental device capable of semi-automatically replacing padding |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120350606.3U CN215012479U (en) | 2021-02-08 | 2021-02-08 | Rat chronic temperature and stress experimental device capable of semi-automatically replacing padding |
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| Publication Number | Publication Date |
|---|---|
| CN215012479U true CN215012479U (en) | 2021-12-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120350606.3U Expired - Fee Related CN215012479U (en) | 2021-02-08 | 2021-02-08 | Rat chronic temperature and stress experimental device capable of semi-automatically replacing padding |
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| Country | Link |
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| CN (1) | CN215012479U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115721437A (en) * | 2022-11-16 | 2023-03-03 | 武汉科技大学 | Mouse chronic fatigue syndrome composite factor modeling device and method |
-
2021
- 2021-02-08 CN CN202120350606.3U patent/CN215012479U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115721437A (en) * | 2022-11-16 | 2023-03-03 | 武汉科技大学 | Mouse chronic fatigue syndrome composite factor modeling device and method |
| CN115721437B (en) * | 2022-11-16 | 2023-09-12 | 武汉科技大学 | Device and method for modeling chronic fatigue syndrome composite factors of mice |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211207 |
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| CF01 | Termination of patent right due to non-payment of annual fee |