CN214969935U - Dialysis system and plasma separation filter - Google Patents
Dialysis system and plasma separation filter Download PDFInfo
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- CN214969935U CN214969935U CN202121003864.0U CN202121003864U CN214969935U CN 214969935 U CN214969935 U CN 214969935U CN 202121003864 U CN202121003864 U CN 202121003864U CN 214969935 U CN214969935 U CN 214969935U
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- 238000000926 separation method Methods 0.000 title claims abstract description 129
- 238000000502 dialysis Methods 0.000 title claims abstract description 20
- 210000004369 blood Anatomy 0.000 claims abstract description 38
- 239000008280 blood Substances 0.000 claims abstract description 38
- 239000002699 waste material Substances 0.000 claims abstract description 22
- 239000007788 liquid Substances 0.000 claims abstract description 21
- 238000001914 filtration Methods 0.000 claims abstract description 12
- 238000007789 sealing Methods 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 2
- 239000000203 mixture Substances 0.000 abstract description 6
- 238000000034 method Methods 0.000 abstract description 5
- 230000004087 circulation Effects 0.000 abstract description 3
- 230000005484 gravity Effects 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract 1
- 230000001473 noxious effect Effects 0.000 abstract 1
- 239000000306 component Substances 0.000 description 65
- 239000000126 substance Substances 0.000 description 18
- 239000003440 toxic substance Substances 0.000 description 11
- 231100000614 poison Toxicity 0.000 description 9
- 239000012528 membrane Substances 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 102000018297 Immunoglobulin subtype Human genes 0.000 description 4
- 108050007411 Immunoglobulin subtype Proteins 0.000 description 4
- 102000004895 Lipoproteins Human genes 0.000 description 4
- 108090001030 Lipoproteins Proteins 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 3
- 239000012503 blood component Substances 0.000 description 3
- 210000000601 blood cell Anatomy 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 231100000167 toxic agent Toxicity 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 238000002648 combination therapy Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 208000028208 end stage renal disease Diseases 0.000 description 1
- 201000000523 end stage renal failure Diseases 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
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Abstract
The utility model discloses a dialysis system and plasma separation filter. The plasma separation filter includes a housing; a plasma separation component used for separating plasma and a plasma component separation component communicated with a plasma discharge port of the plasma separation component and used for filtering the plasma are arranged in the shell; the plasma separation component and the plasma component separation component are respectively positioned at two ends of the shell; the middle part of the shell is provided with a blood inlet, one end of the shell close to the plasma component separation component is provided with a plasma outlet and a waste liquid outlet, and one end of the shell close to the plasma component separation component is provided with a non-plasma outlet; the plasma outlet and the non-plasma outlet are connected in parallel. This plasma separation filter is integrated in same casing with plasma separation subassembly and plasma composition separation subassembly, realizes realizing that the inside of same casing realizes plasma separation and filters the discharge to the noxious material in the plasma, and existing specific gravity that does benefit to reduce blood at patient extracorporeal circulation, and then reduces the risk of treatment process and patient's uncomfortable and feels, can also prolong the life of product.
Description
Technical Field
The utility model relates to a dialysis field especially relates to a plasma separation filter. Also relates to a dialysis system comprising the plasma separation filter.
Background
Dialysis is one of the effective methods for treating end-stage renal failure.
The prior art generally utilizes a plurality of filters in series to filter the patient's blood during treatment. Because the plurality of filters are communicated through the pipeline, the plurality of filters need to be manually connected, and the requirement on an operator is high; the increased number of filters causes an increase in the number and length of the tubes, which in turn leads to an increased proportion of the patient's blood in the extracorporeal circulation, which is liable to cause discomfort to the patient during the treatment and even to increase the risk of the treatment process.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a plasma separation filter not only can ensure blood filtration effect and increase of service life, still is favorable to reducing the proportion of patient's blood at the extrinsic cycle. Another object of the present invention is to provide a dialysis system, comprising the above plasma separation filter.
In order to achieve the above object, the present invention provides a plasma separation filter, comprising a housing; the shell is internally provided with a plasma separation component for separating plasma and a plasma component separation component which is communicated with a plasma discharge port of the plasma separation component and is used for filtering the plasma; the plasma separation component and the plasma component separation component are respectively positioned at two ends of the shell; a blood inlet is formed in the middle of the shell, a plasma outlet and a waste liquid outlet are formed in one end, close to the plasma component separation assembly, of the shell, and a non-plasma outlet is formed in one end, close to the plasma component separation assembly, of the shell; the plasma outlet and the non-plasma outlet are connected in parallel.
Preferably, the waste liquid outlet is communicated with a waste liquid bag.
Preferably, the housing comprises a first housing within which the plasma separation assembly is disposed and a second housing within which the plasma component separation assembly is disposed; the end part of the first shell and the end part of the second shell are sleeved and connected in a sealing mode.
Preferably, an end of the first housing and an end of the second housing are threadedly connected.
Preferably, the first housing and the second housing are coaxially nested.
Preferably, a waterproof seal is provided between the end of the first housing and the end of the second housing that is threadedly connected thereto.
The utility model discloses still provide a dialysis system, include as above plasma separation filter.
Preferably, the pump further comprises a first pump body, a second pump body and a third pump body; the outlet of the first pump body is communicated with the blood inlet; the inlet of the second pump body is communicated with the non-plasma outlet; the inlet of the third pump body is connected to the waste liquid outlet.
Preferably, a dialyzer is also included; the plasma outlet and the non-plasma outlet are in communication with an inlet of the dialyzer.
Compared with the prior art, the utility model provides a plasma separation filter includes the casing and locates plasma separation subassembly and plasma component separation subassembly in the casing.
Wherein the housing is provided with a blood inlet, a plasma outlet, a waste fluid outlet and a non-plasma outlet. Because the plasma separation component and the plasma component separation component are respectively positioned at two ends of the inner cavity of the shell, the blood inlet is arranged in the middle of the shell, namely positioned between the plasma separation component and the plasma component separation component; the plasma outlet and the waste liquid outlet are positioned at the same end of the shell, in particular to the end close to the plasma component separation component; the non-plasma outlet is located at the other end of the housing, specifically the end near the plasma separation assembly.
The plasma separation filter integrates the plasma separation component and the plasma component separation component in the same shell, utilizes the plasma separation component to separate plasma and non-plasma substances in blood, and utilizes the plasma component separation component to filter and separate toxic substances carried by the plasma and the plasma. Blood substances other than plasma in the blood flow out from the non-plasma outlet, plasma in the blood flows out from the plasma outlet alone after filtration, and toxic substances carried by the plasma, such as immunoglobulin subtype containing pathogenic substances, high molecular weight lipoprotein toxoid, flow out from the waste liquid outlet alone after filtration.
Because the plasma outlet and the non-plasma outlet are connected in parallel, when the plasma separation filter is applied to dialysis, non-plasma substances in blood and filtered clean plasma can be collected and form whole blood, and the specific gravity of the blood circulating outside a patient body can be reduced.
Plasma composition separation module is equipped with the waste liquid export, consequently, the toxic substance that plasma composition separation module filtered and obtained can in time discharge plasma composition separation module, avoids aforementioned toxic substance accumulation in plasma composition separation module, can ensure this plasma separation filter's filter effect and life.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a dialysis system provided in an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a plasma separation filter according to an embodiment of the present invention;
FIG. 3 is a front view of FIG. 2;
fig. 4 is a cross-sectional view of fig. 3 taken along a central axis.
The device comprises a shell 1, a first shell 101, a second shell 102, a blood inlet 11, a plasma outlet 12, a waste liquid outlet 13, a non-plasma outlet 14, a plasma separation component 2, a plasma component separation component 3, a waste liquid bag 4, a first pump 5, a second pump 6, a third pump 7, a dialyzer 8 and a liquid supplementing bag 9.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In order to make the technical field of the present invention better understand, the present invention will be described in detail with reference to the accompanying drawings and the detailed description.
Referring to fig. 1 to 4, fig. 1 is a schematic structural diagram of a dialysis system according to an embodiment of the present invention; fig. 2 is a schematic structural diagram of a plasma separation filter according to an embodiment of the present invention; FIG. 3 is a front view of FIG. 2; fig. 4 is a cross-sectional view of fig. 3 taken along a central axis.
The utility model provides a plasma separation filter, including the casing with locate plasma separation subassembly 2 and plasma composition separation subassembly 3 in the casing.
The plasma separation module 2 and the plasma component separation module 3 are located at both ends of the inner cavity of the housing, respectively.
The plasma separation module 2 is used to separate plasma and non-plasma substances in blood. Wherein, the non-plasma substance mainly refers to blood cells and some macromolecular substances in blood, and does not include non-blood substances such as metabolic waste substances with the size close to that of plasma components. The plasma separated by the plasma separation module 2 is discharged from the plasma discharge port separately to the outside, and since the plasma discharge port communicates with the plasma component separation module 3, the separated plasma and the toxic substances carried by the plasma enter the plasma component separation module 3.
The plasma component separation module 3 is used to filter the plasma and achieve separation of the plasma from non-blood substances, such as toxic substances, carried by the plasma.
The plasma separation component 2 can be internally provided with a plasma separation membrane wire, and under the pressure action, plasma in blood enters the membrane wire through the micropores of the plasma separation membrane wire and further enters a plasma component separator; macromolecular blood substances such as blood cells in the blood cannot enter the inside of the membrane filaments and are finally discharged from the plasma separation module 2.
Similarly, the plasma component separation module 3 may be provided with a plasma component separation membrane for separating the plasma from the immunoglobulin subtype and high molecular weight lipoprotein toxoid containing the pathogenic substance. The immunoglobulin subtype and high molecular weight lipoprotein toxoid containing the pathogenic substance separately flow out of the plasma component separation module 3 after filtration and separation, and the plasma containing no immunoglobulin subtype and high molecular weight lipoprotein toxoid containing the pathogenic substance separately flow out of the plasma component separation module 3.
Wherein the average pore diameter of the plasma separation membrane filaments can be set to 300 nm; the average pore diameter of the plasma component separation membrane may be set to any value of 10 to 30 nm.
In addition, the plasma separation module 2 and the plasma component separation module 3 can be referred to the specific structure and functional principle of the plasma separator and the plasma component separator in the prior art.
The middle part of the shell is provided with a blood inlet 11, and the whole blood which is not filtered from the body of the patient enters the shell from the blood inlet 11; one end of the shell, particularly the end close to the plasma component separation component 3, is provided with a plasma outlet 12 and a waste liquid outlet 13 which are used for respectively discharging the plasma and the toxic substances separated by the plasma component separation component 3; the other end of the housing, specifically the end near the plasma separation module 2, is provided with a non-plasma outlet 14 for the outflow of blood components of the whole blood other than plasma.
In this embodiment, the plasma outlet 12 and the non-plasma outlet 14 of the plasma separation filter are connected in parallel, in other words, the clean plasma filtered by the plasma component separation module 3 and the blood component separated by the plasma separation module 2 except the plasma are collected again to form the whole blood without carrying toxic substances, which can be directly returned to the patient or further filtered by other filters.
In summary, the plasma separation filter integrates the plasma separation component 2 and the plasma component separation component 3 in the same shell, and the plasma separation component 2 is used for separating plasma and non-plasma substances in blood, and the plasma component separation component 3 is used for filtering and separating toxic substances carried by the plasma and the plasma, so that plasma separation and filtering and adsorbing of the toxic substances in the plasma are realized in the same shell. Therefore, when the combined type plasma separation perfusion apparatus is applied to dialysis, clean whole blood can be obtained and applied to blood circulation, and the flow path of blood components such as plasma and non-plasma substances is short, so that the proportion of the blood in extracorporeal circulation of a patient is reduced, the risk of a treatment process and the discomfort of the patient are reduced, and the treatment efficiency and the treatment effect are improved.
The plasma separation filter provided by the present invention will be further described with reference to the accompanying drawings and embodiments.
In addition to the above embodiment, the waste liquid outlet 13 is connected to the waste liquid bag 4. The waste liquid bag 4 is used for collecting harmful substances obtained by filtering the plasma component separation assembly 3, so that the influence of the harmful substances accumulated in the plasma component separation assembly 3 on the use effect and the service life of the plasma component separation assembly 3 is avoided, in other words, the filtering effect of the plasma component separation assembly 3 on plasma can be ensured.
The housing adopted by the present invention may include a first housing 101 and a second housing 102; the first housing 101 and the second housing 102 form a complete housing by means of a sealing assembly. The plasma separation module 2 is provided inside the first casing 101, and the plasma component separation module 3 is provided inside the second casing 102.
As for the specific assembling manner of the first housing 101 and the second housing 102, it includes, but is not limited to, screwing, welding, and gluing.
Illustratively, the end of the first housing 101 and the end of the second housing 102 are threaded for easy disassembly and reassembly by a user, thereby facilitating the user's replacement and maintenance of the plasma separation assembly 2 within the first housing 101 and the plasma component separation assembly 3 within the second housing 102.
To ensure the flow of plasma within the plasma component separation assembly 3 and the flow of non-plasma substances within the plasma separation assembly 2, the first housing 101 and the second housing 102 may be coaxially nested. In this case, the plasma separation filter may be provided with a filter net between the plasma separation module 2 and the plasma component separation module 3 for separating and positioning the plasma separation module 2 and the plasma component separation module 3.
In general, both the first housing 101 and the second housing 102 may be provided as cylindrical housings, and the radial dimensions of both the first housing 101 and the second housing 102 may be equally large.
In addition, a waterproof sealing member, such as a rubber sealing ring, is disposed between the end of the first casing 101 and the end of the second casing 102 screwed thereto, so as to further ensure the sealing effect of the first casing 101 and the second casing 102 and prevent the blood in the casings from leaking outwards.
The utility model also provides a dialysis system, including the plasma separation filter that above-mentioned embodiment provided.
The dialysis system includes a first pump body 5, a second pump body 6, and a third pump body 7 in addition to the plasma separation filter. The outlet of the first pump body 5 is communicated with the blood inlet 11 for pumping the unfiltered whole blood flowing out of the patient into the housing; the inlet of the second pump body 6 is communicated with the non-plasma outlet 14 and is used for providing power for the blood in the shell so as to realize plasma separation by combining the first pump body 5 and the plasma separation component 2; the inlet of the third pump body 7 is connected to the waste liquid outlet 13 for pumping out the toxic substances filtered and separated by the plasma component separation module 3 from the waste liquid outlet 13.
Wherein, the first pump body 5, the second pump body 6 and the third pump body 7 can adopt peristaltic pumps, and the flow rate and the flow at each position are conveniently controlled.
Further, the plasma outlet 12 and the non-plasma outlet 14 are connected to the inlet of the dialyzer 8, i.e., the dialysis system may further comprise the dialyzer 8 for further filtering the blood to achieve a combination therapy that more thoroughly eliminates each molecular weight toxin in one treatment, and retains as much of the beneficial components in the plasma as possible.
As for other structures of the dialysis system, such as connecting pipes, fluid infusion bags, etc., reference can be made to the related structure arrangement in the prior art.
The dialysis system and the plasma separation filter provided by the present invention have been described in detail above. The principles and embodiments of the present invention have been explained herein using specific examples, and the above descriptions of the embodiments are only used to help understand the method and its core ideas of the present invention. It should be noted that, for those skilled in the art, without departing from the principle of the present invention, the present invention can be further modified and modified, and such modifications and modifications also fall within the protection scope of the appended claims.
Claims (9)
1. A plasma separation filter, characterized by comprising a housing (1); a plasma separation component (2) used for separating plasma and a plasma component separation component (3) which is communicated with a plasma discharge port of the plasma separation component (2) and used for filtering the plasma are arranged in the shell (1); the plasma separation component (2) and the plasma component separation component (3) are respectively positioned at two ends of the shell (1); a blood inlet (11) is formed in the middle of the shell (1), a plasma outlet (12) and a waste liquid outlet (13) are formed in one end, close to the plasma component separation assembly (3), of the shell (1), and a non-plasma outlet (14) is formed in one end, close to the plasma component separation assembly (2), of the shell (1); the plasma outlet (12) and the non-plasma outlet (14) are connected in parallel.
2. Plasma separation filter according to claim 1, characterised in that the waste liquid outlet (13) communicates with a waste liquid bag (4).
3. Plasma separation filter according to claim 1, characterized in that the housing (1) comprises a first housing (101) inside which the plasma separation assembly (2) is arranged and a second housing (102) inside which the plasma component separation assembly (3) is arranged; the end part of the first shell (101) and the end part of the second shell (102) are sleeved and connected in a sealing mode.
4. The plasma separation filter according to claim 3, characterized in that the end of the first housing (101) and the end of the second housing (102) are screwed.
5. The plasma separation filter according to claim 4, wherein the first housing (101) and the second housing (102) are coaxially nested.
6. Plasma separation filter according to claim 4, characterized in that a watertight seal is provided between the end of the first housing (101) and the end of the second housing (102) screwed thereto.
7. A dialysis system comprising the plasma separation filter of any one of claims 1 to 6.
8. Dialysis system according to claim 7, further comprising a first pump body (5), a second pump body (6) and a third pump body (7); the outlet of the first pump body (5) is in communication with the blood inlet (11); the inlet of the second pump body (6) communicates with the non-plasma outlet (14); the inlet of the third pump body (7) is connected to the waste liquid outlet (13).
9. The dialysis system of claim 7, further comprising a dialyzer (8); the plasma outlet (12) and the non-plasma outlet (14) communicate with an inlet of the dialyzer (8).
Priority Applications (1)
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CN202121003864.0U CN214969935U (en) | 2021-05-11 | 2021-05-11 | Dialysis system and plasma separation filter |
Applications Claiming Priority (1)
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CN202121003864.0U CN214969935U (en) | 2021-05-11 | 2021-05-11 | Dialysis system and plasma separation filter |
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CN214969935U true CN214969935U (en) | 2021-12-03 |
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CN202121003864.0U Active CN214969935U (en) | 2021-05-11 | 2021-05-11 | Dialysis system and plasma separation filter |
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2021
- 2021-05-11 CN CN202121003864.0U patent/CN214969935U/en active Active
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