CN210844570U - Dual plasma exchange device - Google Patents
Dual plasma exchange device Download PDFInfo
- Publication number
- CN210844570U CN210844570U CN201921032795.9U CN201921032795U CN210844570U CN 210844570 U CN210844570 U CN 210844570U CN 201921032795 U CN201921032795 U CN 201921032795U CN 210844570 U CN210844570 U CN 210844570U
- Authority
- CN
- China
- Prior art keywords
- plasma
- separator
- pump
- outlet
- inlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- External Artificial Organs (AREA)
Abstract
The utility model discloses a double plasma replacement device, which comprises a blood pump, a plasma separator, a vein pot, a waste slurry pump and a waste slurry collecting bag, wherein the inlet of the blood pump is used for being connected with the arterial end of a patient, the outlet of the blood pump is connected with the inlet of the plasma separator, the first outlet of the plasma separator is connected with the inlet of the vein pot, and the outlet of the vein pot is used for being connected with the venous end of the patient; the outlet of the waste slurry pump is connected with a waste slurry bag; also comprises a plasma separating pump and a plasma component separator; the second outlet of the plasma separator is connected with the inlet of the plasma component separator through a plasma separating pump, the first outlet of the plasma component separator is connected with the inlet of the waste plasma pump, and the second outlet of the plasma component separator is connected with the inlet of the venous kettle. The double plasma exchange device of the utility model filters the plasma twice and selectively removes macromolecular pathogenic substances; meanwhile, after secondary filtration, the concentration of pathogenic substances in the blood plasma pumped by the waste plasma pump is very high, so that a large amount of pathogenic substances can be removed once.
Description
Technical Field
The utility model belongs to the technical field of medical care, in particular to dual plasma exchange device.
Background
Plasmapheresis (PE) is a blood purification therapy used to remove large molecules from blood. As shown in fig. 1, the existing plasma replacement device comprises a blood pump 1, a plasma separator 2, a venous pot 3, a waste plasma pump 4 and a waste plasma collecting bag 5, wherein an inlet of the blood pump 1 is used for being connected with an arterial end of a patient, an outlet of the blood pump 1 is connected with an inlet of the plasma separator 2, a first outlet of the plasma separator 2 is connected with an inlet of the venous pot 3, a second outlet of the plasma separator 2 is connected with the waste plasma collecting bag 5 through the waste plasma pump 4, and an outlet of the venous pot 3 is used for being connected with a venous end of the patient. The working process is as follows: the blood pump 1 is used for feeding blood into the plasma separator 2 from the arterial end of a patient, the plasma mixed with harmful substances is pumped into the waste plasma collecting bag 5 by the waste plasma pump 4 after the plasma is filtered by the plasma separator 2, and the residual plasma enters the venous pot 3 and finally returns to the venous end of a human body.
The existing plasmapheresis devices have the following disadvantages:
first, since the separation accuracy of the plasma separator 2 is low, it is impossible to selectively remove the macromolecular pathogenic factors. Thus, for therapeutic purposes, the large amount of plasma exiting the second outlet of the plasma separator 2 is eventually discarded, resulting in the loss of proteins, coagulation factors. Therefore, the replacement fluid in the replacement fluid bag 8 needs to be pumped by the replacement pump 9 to supplement the replacement fluid, and this method needs to supplement a large amount of plasma to supplement a large amount of necessary substances such as proteins and blood coagulation factors necessary for the human body, but a large amount of blood products such as plasma are often infused, which increases the risk of infection.
Second, the treatment is non-specific and does not selectively remove pathogenic agents.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a dual plasma exchange device, to above-mentioned prior art not enough, harmful substance concentration is high in the plasma that pumps through useless thick liquid pump, can get rid of pathogenic substance in a large number by the single, can also realize the selectivity simultaneously and get rid of pathogenic substance.
In order to solve the technical problem, the utility model discloses the technical scheme who adopts is:
a dual plasma replacement device comprises a blood pump, a plasma separator, a venous pot, a waste slurry pump and a waste slurry collecting bag, wherein an inlet of the blood pump is connected with an arterial end of a patient, an outlet of the blood pump is connected with an inlet of the plasma separator, a first outlet of the plasma separator is connected with an inlet of the venous pot, and an outlet of the venous pot is connected with a venous end of the patient; the outlet of the waste slurry pump is connected with a waste slurry collecting bag; it is characterized in that the plasma separator also comprises a plasma separating pump and a plasma component separator; the second outlet of the plasma separator is connected with the inlet of the plasma component separator through a plasma separating pump, the first outlet of the plasma component separator is connected with the inlet of the waste plasma pump, and the second outlet of the plasma component separator is connected with the inlet of the venous kettle.
Compared with the prior art, the utility model discloses at first adopt ordinary plasma separator (first grade membrane) to separate plasma and blood cell, adopt plasma composition separator (second grade membrane) to carry out the secondary separation to the less protein of molecular weight relatively again. After the secondary separation, the plasma containing macromolecular pathogenic substances is pumped into a waste plasma collecting bag by a waste plasma pump and is discarded, and plasma protein containing albumin and the like with relatively small molecular weight is returned to a human body.
The plasma component separator is a membrane separator for separating large molecular proteins and small molecular proteins from plasma, and the average pore size (representing the size of molecular weight cut-off) of the membrane is between that of a hemofiltration filter and that of a plasma separator. According to the different molecular weight of the pathogenic substance to be removed, the plasma component separator with different membrane pore diameters can be made for the treatment of different diseases. Taking the product of Asahi Kasei Corp., Japan, the plasma component separators are classified into four different types, EC20W, EC30W, EC40W and EC50W, from small to large according to the pore size of the membrane. The aperture of the EC20W membrane is 0.01 um, the aperture of the EC30w membrane is 0.02 um, the aperture of the EC40W membrane is 0.03 um, and the aperture of the EC50W membrane is 0.035 um. The plasma component separator can be selected according to the molecular weight of pathogenic substances to be removed in different diseases.
Therefore, the double plasma exchange device of the utility model filters the plasma twice to selectively remove the macromolecular pathogenic substances; meanwhile, after secondary filtration, the concentration of pathogenic substances in the blood plasma pumped by the waste plasma pump is very high, so that a large amount of pathogenic substances can be removed once.
Drawings
Fig. 1 is a schematic diagram of a prior art structure.
Fig. 2 is a schematic structural diagram of an embodiment of the present invention.
Wherein, 1 is a blood pump, 2 is a plasma separator, 3 is a venous kettle, 4 is a waste slurry pump, 5 is a waste slurry collecting bag, 6 is a slurry separating pump, 7 is a plasma component separator, 8 is a replacement liquid bag, and 9 is a replacement pump.
Detailed Description
As shown in fig. 1, the dual plasma replacement device comprises a blood pump 1, a plasma separator 2, a venous pot 3, a waste plasma pump 4 and a waste plasma collecting bag 5, wherein an inlet of the blood pump 1 is connected with an arterial end of a patient, an outlet of the blood pump 1 is connected with an inlet of the plasma separator 2, a first outlet of the plasma separator 2 is connected with an inlet of the venous pot 3, and an outlet of the venous pot 3 is connected with a venous end of the patient; the outlet of the waste slurry pump 4 is connected with a waste slurry collecting bag 5; also comprises a plasma separating pump 6 and a plasma component separator 7; the second outlet of the plasma separator 2 is connected with the inlet of a plasma component separator 7 through a plasma separating pump 6, the first outlet of the plasma component separator 7 is connected with the inlet of a waste slurry pump 4, and the second outlet of the plasma component separator 7 is connected with the inlet of a venous pot 3.
Compared with the prior art, the utility model discloses at first adopt ordinary plasma separator 2 (first grade membrane) to separate plasma and blood cell, adopt plasma composition separator 7 (second grade membrane) to carry out the secondary separation to the less protein of molecular weight relatively again. After the second separation, the plasma containing macromolecular pathogenic substances is pumped into a waste slurry collecting bag 5 by a waste slurry pump 4 to be discarded, and the plasma protein containing albumin and other plasma proteins with relatively small molecular weight is returned to the human body.
The plasma component separator 7 is a membrane separator for separating large molecular proteins and small molecular proteins from plasma, and has a membrane having an average pore size (size representing a molecular weight cut-off) between a hemofiltration filter and the plasma separator 2. According to the different molecular weight of the pathogenic substance, the plasma component separator 7 with different membrane pore diameters can be made for different diseases. Taking the product of Asahi Kasei Corp., Japan, the plasma component separator 7 is classified into four different types, EC20M, EC30W, EC40W and EC50W, from small to large according to the pore size of the membrane. The aperture of the EC20W membrane is 0.01 um, the aperture of the EC30w membrane is 0.02 um, the aperture of the EC40W membrane is 0.03 um, and the aperture of the EC50W membrane is 0.035 um. The plasma component separator can be selected according to the molecular weight of pathogenic substances to be removed in different diseases.
The embodiments of the present invention have been described with reference to the accompanying drawings, but the present invention is not limited to the above-mentioned embodiments, which are only illustrative and not restrictive, and those skilled in the art can make many forms without departing from the spirit and scope of the present invention, which is within the protection scope of the present invention.
Claims (1)
1. A double plasma replacement device comprises a blood pump (1), a plasma separator (2), a venous pot (3), a waste slurry pump (4) and a waste slurry collecting bag (5), wherein the inlet of the blood pump (1) is connected with the arterial end of a patient, the outlet of the blood pump (1) is connected with the inlet of the plasma separator (2), the first outlet of the plasma separator (2) is connected with the inlet of the venous pot (3), and the outlet of the venous pot (3) is connected with the venous end of the patient; the outlet of the waste slurry pump (4) is connected with a waste slurry collecting bag (5);
characterized in that the plasma separator also comprises a plasma separating pump (6) and a plasma component separator (7); the second outlet of the plasma separator (2) is connected with the inlet of the plasma component separator (7) through the plasma separating pump (6), the first outlet of the plasma component separator (7) is connected with the inlet of the waste slurry pump (4), and the second outlet of the plasma component separator (7) is connected with the inlet of the venous kettle (3).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921032795.9U CN210844570U (en) | 2019-07-04 | 2019-07-04 | Dual plasma exchange device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921032795.9U CN210844570U (en) | 2019-07-04 | 2019-07-04 | Dual plasma exchange device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210844570U true CN210844570U (en) | 2020-06-26 |
Family
ID=71301736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921032795.9U Active CN210844570U (en) | 2019-07-04 | 2019-07-04 | Dual plasma exchange device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210844570U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114225140A (en) * | 2021-10-29 | 2022-03-25 | 南京国青血液净化科技有限公司 | Extracorporeal circulation system for dual plasma replacement |
| CN114225141A (en) * | 2021-10-29 | 2022-03-25 | 南京国青血液净化科技有限公司 | Adsorption filtration purification system for plasmapheresis treatment |
-
2019
- 2019-07-04 CN CN201921032795.9U patent/CN210844570U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114225140A (en) * | 2021-10-29 | 2022-03-25 | 南京国青血液净化科技有限公司 | Extracorporeal circulation system for dual plasma replacement |
| CN114225141A (en) * | 2021-10-29 | 2022-03-25 | 南京国青血液净化科技有限公司 | Adsorption filtration purification system for plasmapheresis treatment |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4579692B2 (en) | Method and apparatus for separating whole blood into erythrocyte concentrate, platelet-containing plasma and, where appropriate, cell-free plasma under the action of gravity | |
| CN210844570U (en) | Dual plasma exchange device | |
| Ronco et al. | First clinical experience with an adjunctive hemoperfusion device designed specifically to remove ß2-microglobulin in hemodialysis | |
| CN102500005B (en) | Blood transfusion system for autologous blood recovery, filtration and purification | |
| CN208943042U (en) | For treating the plasma filtering device of hyperlipidemia | |
| CN203507201U (en) | Separating type hemodialysis absorber | |
| JP2001061955A (en) | Autotransfusion device and method | |
| JPH0261265B2 (en) | ||
| CN203619966U (en) | Blood ascites purifying device for hemodiafiltration joint ascites ultrafiltration and reinfusion | |
| CN204379871U (en) | A kind of hemoperfusion cascading hemodialysis filtration system | |
| CN203354984U (en) | Plasma exchange adsorption filtration purification system for preparing square plasma storage pond | |
| CN203677608U (en) | Device for adopting CRRT machine to perform blood purification united ascites ultra-filtration reinfusion | |
| CN114225141A (en) | Adsorption filtration purification system for plasmapheresis treatment | |
| CN205626598U (en) | Multi -functional recovery system of autoblood | |
| CN106377812B (en) | A kind of plasma circulation acceleration purification system | |
| JPS5911865A (en) | Blood purifier | |
| CN208552666U (en) | A kind of plasma exchange dialysis adsorption system | |
| CN203989183U (en) | The apparatus for purifying blood of integrated strip hemoperfusion and hemodialysis structure | |
| CN106512121A (en) | Method and filtering device for removing AIDS viruses | |
| CN203329103U (en) | Double-pump hemodialysis machine used for conducting plasma adsorption treatment | |
| CN206026804U (en) | Infusion utensil is with automatic bubble device that removes | |
| CN210583234U (en) | Blood component separation and multiple adsorption system of plasma molecule | |
| CN209864813U (en) | Blood component separation and multiple clean system of plasma molecule | |
| JPS6362B2 (en) | ||
| CN216319191U (en) | Half whole blood replacement device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20210923 Address after: 510000 703, Tower B, 191 TIYU West Road, Tianhe District, Guangzhou, Guangdong Province (office only) Patentee after: Guangzhou Beishan Medical Technology Co., Ltd Address before: 410008 Hunan province Changsha Kaifu District, Xiangya Road No. 87 Patentee before: XIANGYA HOSPITAL, CENTRAL SOUTH University |
|
| TR01 | Transfer of patent right |