CN214962242U

CN214962242U - Automatic change liquid nitrogen biological sample storage device

Info

Publication number: CN214962242U
Application number: CN202121679920.2U
Authority: CN
Inventors: 王兴宇
Original assignee: Suzhou Carbon Card Intelligent Technology Co ltd
Current assignee: Suzhou Carbon Card Intelligent Technology Co ltd
Priority date: 2021-07-22
Filing date: 2021-07-22
Publication date: 2021-12-03
Anticipated expiration: 2031-07-22

Abstract

The utility model provides an automatic change liquid nitrogen biological sample storage device, including the cabinet body, central channel, sample cell, sample cabinet, liquid nitrogen main channel, liquid nitrogen branch passageway, interlayer the central channel runs through the centre of a circle of cylinder upper and lower bottom surface, the central point of central channel puts and is provided with the pivot, and many liquid nitrogen main channels are being distributed to equidistance around the pivot, be provided with a plurality of liquid nitrogen branch passageways on the passageway wall of liquid nitrogen main channel, the left side of the cabinet body is provided with multilayer sample cell, the left and right sides of sample cell is provided with the slide rail respectively, links through the pulley between the slide rail that belongs to have the liquid level board, a plurality of holes have been seted up on the liquid level board, the below of sample cell is provided with slider; the right side of the cabinet body is provided with the multilayer sample cabinet, the sample cabinet sets up to the drawer structure, sample cabinet inside is provided with a plurality of cryopreserved pipe racks. The utility model provides a difficult problem of drawing and unable realization automation and datamation of biological sample.

Description

Automatic change liquid nitrogen biological sample storage device

Technical Field

The utility model relates to a storage device, especially an automatic change liquid nitrogen biological sample storage device.

Background

Long term storage of biological samples typically uses as low a temperature as possible to reduce biochemical reactions within the sample and to improve the stability of various components within the sample. Common storage temperatures for biomacromolecules, cells, tissues and organs are-800 ℃ (ultra-low temperature refrigerator), -1400 ℃ (liquid nitrogen gas phase or cryogenic refrigerator) and-1960 ℃ (liquid nitrogen liquid phase), the lower the temperature the longer the stable storage time of the sample. The temperature of 0 to-600 ℃ is the crystallization temperature of water, easily causes damage to cells and microstructures of tissues, and the temperature is not generally used for preserving the tissues and the cells. Part of purified biological macromolecules can be stably stored for a certain time at 0-600 ℃, but the biological macromolecules in a tissue sample are influenced by various factors in cell tissues, and the stability is possibly obviously reduced, so that the sample library does not use 0-600 ℃ as the storage temperature.

The commonly used liquid nitrogen biological sample storage device often needs to rotate the target to the opening part, and the hand-basket is lifted manually, takes out the freezing dish of a certain layer, but this kind of method can't realize datamation and automation, and the operation is wasted time and energy, consequently needs an automatic liquid nitrogen biological sample storage device urgently.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing an automatic change liquid nitrogen biological sample storage device.

The utility model provides a following technical scheme:

an automatic liquid nitrogen biological sample storage device is characterized by comprising a cabinet body, a central channel, a sample pool, a sample cabinet, a liquid nitrogen main channel, a liquid nitrogen branch channel and an interlayer, the whole cabinet body is a cuboid, the top end of the cabinet body is provided with an LED screen, the central channel penetrates through the circle centers of the upper bottom surface and the lower bottom surface of the cylinder, a rotating shaft is arranged at the central position of the central channel, a plurality of liquid nitrogen main channels are distributed around the rotating shaft at equal intervals, a plurality of liquid nitrogen branch channels are arranged on the channel wall of the liquid nitrogen main channel, a valve is arranged between the liquid nitrogen main channel and the liquid nitrogen branch channels, a plurality of layers of sample tanks are arranged on the left side of the cabinet body, slide rails are respectively arranged on the left side and the right side of each sample tank, liquid level plates are connected between the slide rails through pulleys in a chain manner, the liquid level plate is provided with a plurality of holes, and a sliding device is arranged below the sample cell;

the right side of the cabinet body is provided with multilayer sample cabinet, the sample cabinet sets up to the drawer structure, the inside a plurality of pipe racks that deposit that freeze that is provided with of sample cabinet, the right side of sample cabinet is provided with sealing door, and sealing door's right side is provided with on being located the position of the cabinet body and gets the thing door, the most lower position of sample cell and sample cabinet is provided with liquid nitrogen source one and liquid nitrogen source two respectively.

Preferably, the sample cell is provided with 7 layers, each layer of sample cell is equally divided into 3 intervals according to the area, and each interval corresponds to a fetching door.

Preferably, the sample cabinet is provided with 7 layers, each layer of sample cabinet is equally divided into 3 intervals, each interval corresponds to one fetching door, and the freezing pipe racks in each layer of sample cabinet are sequentially arranged from top to bottom and from small to large.

Preferably, the bottom of the cabinet body is provided with 4 universal wheels.

Preferably, the part of the right side of the sample cell, which is in contact with the central channel, is provided with a recovery hole.

Preferably, a liquid level sensing head and a liquid level sensing line are arranged in the middle of the sample cell.

The utility model has the advantages that:

1. two storage modes of a vapor phase and a liquid phase are realized by arranging the sample pool and the sample cabinet, and the two storage modes are mutually independent and do not interfere with each other and can not pollute each other.

2. The liquid level sensing head and the liquid level sensor line are arranged in the sample pool, so that the height of the liquid level plate can be controlled, and the consumption of liquid-phase liquid nitrogen can be further controlled.

3. The samples in the sample cell and the sample cabinet can be directly taken out through the fetching door, and time and labor are saved.

Drawings

The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention. In the drawings:

fig. 1 is a front view of the present invention;

FIG. 2 is a schematic diagram of the structure of the central channel;

notation in the figure: 1 is the cabinet body, 2 is central channel, 3 is the sample cell, 4 is the slide rail, 5 is the liquid level board, 6 is liquid level sensing head, 7 is slider, 8 is the level sensor line, 9 is the recovery hole, 10 is the sample cabinet, 11 are for getting the thing door, 12 are for freezing the pipe support of depositing, 13 are sealing door, 14 are liquid nitrogen main channel, 15 are liquid nitrogen branch's passageway, 16 are liquid nitrogen source one, 17 are liquid nitrogen source two, 18 are the LED screen, 19 are the interlayer.

Detailed Description

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", and the like, indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention. In the present invention, unless otherwise expressly stated or limited, the terms "disposed," "mounted," "connected," and "fixed" are to be construed broadly, e.g., as meaning either a fixed connection or a removable connection; may be a mechanical connection; may be directly connected or indirectly connected through an intermediate. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art. Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature.

As shown in fig. 1-2, an automatic liquid nitrogen biological sample storage device comprises a cabinet body 1, a central channel 2, a sample pool 3, a sample cabinet 10, a liquid nitrogen main channel 14, liquid nitrogen branch channels 15, and an interlayer 19, wherein the whole cabinet body 1 is a cuboid, an LED screen 18 is arranged at the top end of the cabinet body 1, the central channel 2 penetrates through the centers of the upper and lower bottom surfaces of a cylinder, a rotating shaft is arranged at the central position of the central channel 2, a plurality of liquid nitrogen main channels 14 are equidistantly distributed around the rotating shaft, a plurality of liquid nitrogen branch channels 15 are arranged on the wall of the liquid nitrogen main channel 14, a valve is arranged between the liquid nitrogen main channel 14 and the liquid nitrogen branch channels 15, a plurality of layers of sample pools 3 are arranged on the left side of the cabinet body 1, slide rails 4 are respectively arranged on the left and right sides of the sample pools 3, and liquid level plates 5 are linked between the slide rails 4 through pulleys, a plurality of holes are formed in the liquid level plate 5, and a sliding device 7 is arranged below the sample cell 3;

the right side of the cabinet body 1 is provided with multilayer sample cabinet 10, sample cabinet 10 sets up to the drawer structure, sample cabinet 10 is inside to be provided with a plurality of freezes and deposits pipe support 12, sample cabinet 10's right side is provided with sealing door 13, and sealing door 13's right side is provided with on the position of the cabinet body 1 and gets thing door 11, the most lower position of sample cell 3 and sample cabinet 10 is provided with liquid nitrogen source one 16 and liquid nitrogen source two 17 respectively.

The sample cell 3 is provided with 7 layers, and every layer of sample cell 3 equally divide into 3 intervals according to the area, and every interval correspondence has one to get thing door 11. The sample cabinet 10 is provided with 7 layers, each layer of sample cabinet 10 is equally divided into 3 intervals, each interval corresponds to one fetching door 11, and the freezing pipe racks 12 in each layer of sample cabinet 10 are sequentially arranged from top to bottom from small to large. 4 universal wheels are arranged at the bottom of the cabinet body 1. The portion of the right side of the sample cell 3 in contact with the central passage 2 is provided with a recovery hole 9. The middle position of the sample cell 3 is provided with a liquid level sensing head 6 and a liquid level sensing line 8.

The utility model discloses a theory of operation is: after the biological sample is placed in the sample cell 3 or the sample cabinet 10, the corresponding liquid nitrogen source one 16 or liquid nitrogen source two 17 is started by a motor (not shown) and a pump body (not shown), so that the liquid nitrogen is transported upwards through the liquid nitrogen main channel 14, and the corresponding valve is opened through the LED screen 18, so that the liquid nitrogen enters the sample cabinet 10 and the sample cell 3 respectively in a gas form or a liquid form. After liquid nitrogen enters the sample pool 3, the liquid level sensing head 6 and the liquid level sensing line 8 monitor the liquid level of the liquid nitrogen, and the liquid level sensing head and the liquid level sensing line carry out appropriate liquid nitrogen supplement through the liquid nitrogen branch channel 15, and the liquid level plate 5 can slide up and down in time through the slide rail 4. When the sample pool 3 is pulled out, the fetching door 11 is opened, and a sample needs to be fetched, the recovery hole 9 starts to generate suction force to prevent the leakage of liquid nitrogen. The sample holder 10 on the right side operates in the same manner as the sample cell.

Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing embodiments, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The automatic liquid nitrogen biological sample storage device is characterized by comprising a cabinet body (1), a central channel (2), a sample pool (3), a sample cabinet (10), a liquid nitrogen main channel (14), liquid nitrogen branch channels (15) and an interlayer (19), wherein the whole cabinet body (1) is a cuboid, an LED screen (18) is arranged at the top end of the cabinet body (1), the central channel (2) penetrates through the circle centers of the upper and lower bottom surfaces of a cylinder, a rotating shaft is arranged at the central position of the central channel (2), the liquid nitrogen main channels (14) are distributed around the rotating shaft at equal intervals, a plurality of liquid nitrogen branch channels (15) are arranged on the channel wall of the liquid nitrogen main channel (14), a valve is arranged between the liquid nitrogen main channel (14) and the liquid nitrogen branch channels (15), and a plurality of layers of sample pools (3) are arranged on the left side of the cabinet body (1), the left side and the right side of the sample cell (3) are respectively provided with a slide rail (4), a liquid level plate (5) is connected between the slide rails (4) through a pulley, a plurality of holes are formed in the liquid level plate (5), and a sliding device (7) is arranged below the sample cell (3);

the right side of the cabinet body (1) is provided with multilayer sample cabinet (10), sample cabinet (10) sets up to the drawer structure, sample cabinet (10) inside is provided with a plurality of freezes and deposits pipe support (12), the right side of sample cabinet (10) is provided with sealing door (13), is provided with on the right side of sealing door (13) is located the position of the cabinet body (1) and gets thing door (11), the most lower position of sample cell (3) and sample cabinet (10) is provided with liquid nitrogen source one (16) and liquid nitrogen source two (17) respectively.

2. The automated liquid nitrogen biological sample storage device according to claim 1, wherein the sample pools (3) are arranged in 7 layers, each layer of the sample pools (3) is divided into 3 equal intervals according to the area, and each interval corresponds to one fetching door (11).

3. The automatic liquid nitrogen biological sample storage device according to claim 1, wherein the sample cabinets (10) are provided with 7 layers, each layer of sample cabinets (10) is equally divided into 3 sections, each section corresponds to one fetching door (11), and the freezing storage pipe racks (12) in each layer of sample cabinets (10) are sequentially arranged from top to bottom and from small to large.

4. The automated liquid nitrogen biological sample storage device according to claim 1, wherein the bottom of the cabinet body (1) is provided with 4 universal wheels.

5. An automated liquid nitrogen biological sample storage device according to claim 1, characterized in that the part of the right side of the sample cell (3) in contact with the central channel (2) is provided with a recovery hole (9).

6. An automated liquid nitrogen biological sample storage device according to claim 1, characterized in that the middle position of the sample cell (3) is provided with a liquid level sensing head (6) and a liquid level sensing line (8).