CN213631099U - Ultralow temperature storage system - Google Patents
Ultralow temperature storage system Download PDFInfo
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- CN213631099U CN213631099U CN202022393723.6U CN202022393723U CN213631099U CN 213631099 U CN213631099 U CN 213631099U CN 202022393723 U CN202022393723 U CN 202022393723U CN 213631099 U CN213631099 U CN 213631099U
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Abstract
The utility model relates to an ultra-low temperature storage system, which comprises a system frame, an ultra-low temperature storage device, an auxiliary opening and closing device, a vacuum generating device and a sample transportation device, wherein the ultra-low temperature storage device, the auxiliary opening and closing device, the vacuum generating device and the sample transportation device are arranged on the system frame; the auxiliary opening and closing device is matched with a cover plug of the ultralow temperature storage device to expose the freezing storage tube, and the vacuum generating device is connected with the sample conveying device and moves to a preset position under the driving of the sample conveying device to take and place the freezing storage tube; the ultra-low temperature storage device comprises a liquid nitrogen tank, a metal disc and a plurality of metal tubes, wherein the metal disc and the metal tubes are installed in the liquid nitrogen tank, a plurality of through holes which are communicated from top to bottom are distributed on the metal disc, and the plurality of through holes which are inserted into the metal disc and correspond to the plurality of metal tubes one to one are suspended in the liquid nitrogen tank. The utility model can automatically take samples, avoid excessive external interference, improve the efficiency and the space utilization rate, and improve the safe reliability of storage and sampling; the utility model discloses a densely covered formula alloy pipe subassembly stores and freezes the deposit pipe, convenient manufacturing, low cost.
Description
Technical Field
The utility model relates to a biological sample ultra-low temperature stores relevant technical field, concretely relates to ultra-low temperature storage system especially relates to a system that can full-automatic storage biological sample.
Background
The biological sample bank is also called biological bank (Biobank) and mainly refers to standardized collection, treatment, storage and application of samples such as biological macromolecules, cells, tissues and organs of healthy and disease organisms, including human organ tissues, whole blood, blood plasma, blood serum, biological body fluid or treated biological samples (DNA, RNA, protein and the like), and clinical, pathological, treatment, follow-up visit, informed consent and other data related to the biological samples, and a quality control, information management and application system thereof.
After a certain amount of samples are accumulated, manual searching and storing of the samples are difficult and error-prone, and the utilization efficiency of containers (such as refrigerators and liquid nitrogen tanks) for storing the samples is gradually reduced. Because the samples may be stored in a sorted order initially, but depending on the scientific needs, the samples are taken from different positions of the container, and a large amount of scattered vacant space is generated in the container after a period of time, and the scattered vacant space cannot be effectively utilized. Therefore, an information system is needed to automatically allocate and search the sample storage positions, and the space utilization efficiency of the container is improved.
At present, some low-temperature storage systems exist at home and abroad, but the low-temperature storage systems are high in price or need to operate the whole cryopreservation box, and other cryopreservation tubes are easily influenced.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the technical problem that to prior art not enough, provide an ultra-low temperature storage system.
The utility model provides an above-mentioned technical problem's technical scheme as follows: an ultra-low temperature storage system comprises a system frame, and an ultra-low temperature storage device, an auxiliary opening and closing device, a vacuum generating device and a sample transportation device which are arranged on the system frame; the auxiliary opening and closing device is matched with a cover plug of the ultralow-temperature storage device to expose the cryopreservation tube, and the vacuum generating device is connected with the sample conveying device and moves to a preset position under the driving of the sample conveying device to take and place the cryopreservation tube; the ultra-low temperature storage device comprises a liquid nitrogen tank, a metal disc and a plurality of metal tubes, wherein the metal disc and the metal tubes are arranged in the liquid nitrogen tank, a plurality of through holes which are communicated from top to bottom are distributed on the metal disc, and the metal tubes are inserted into the through holes of the metal disc in a one-to-one correspondence manner and are suspended in the liquid nitrogen tank.
The utility model has the advantages that: the utility model discloses an ultra-low temperature storage system can get the sample automatically, avoids too much external interference, improves efficiency and space utilization, improves the safe reliability of storage and sample; the utility model discloses a densely covered formula alloy pipe subassembly stores and freezes the deposit pipe, convenient manufacturing, low cost.
On the basis of the technical scheme, the utility model discloses can also do following improvement.
Furthermore, a circle of annular shoulder is arranged on the outer side wall, close to the upper end, of the metal pipe, and the metal pipe is erected on the metal disc through the annular shoulder.
The beneficial effect of adopting the further scheme is that: the metal pipe can be suspended on the metal disc by arranging the annular circular bead on the outer side wall of the metal pipe, and the metal pipes with different lengths can be arranged as required.
Further, the metal plate is an aluminum plate, and the metal pipe is an aluminum alloy pipe formed by stamping, machining or casting.
The beneficial effect of adopting the further scheme is that: convenient manufacture and low cost.
The liquid nitrogen storage tank is internally provided with a liquid level sensor and a temperature sensor, wherein the liquid level sensor and/or the temperature sensor are/is connected with the system display controller;
the external refrigeration assembly comprises a liquid nitrogen replenishing tank and an automatic liquid replenishing system, the automatic liquid replenishing system is respectively connected with the liquid nitrogen replenishing tank and the liquid nitrogen tank, and the system display controller is connected with the automatic liquid replenishing system and is used for controlling the automatic liquid replenishing system to convey liquid nitrogen in the liquid nitrogen replenishing tank into the liquid nitrogen tank; and the external refrigeration assembly comprises a low-temperature refrigerator, and the system display controller is connected with the low-temperature refrigerator.
The beneficial effect of adopting the further scheme is that: the temperature sensor can monitor the internal temperature of the liquid nitrogen tank in real time, the storage reliability of the cryopreservation pipe can be ensured, the liquid level sensor can monitor the amount of liquid nitrogen in the liquid nitrogen tank, and the liquid nitrogen tank can be automatically refrigerated through the external refrigeration assembly; when level sensor detected need supply liquid nitrogen in the liquid nitrogen jar, liquid nitrogen of liquid nitrogen fluid infusion jar can also set up level sensor in the liquid nitrogen fluid infusion jar automatically supply liquid nitrogen jar, when level sensor in the liquid nitrogen fluid infusion jar detected the liquid nitrogen not enough, can automatic alarm remind the replenishment, the liquid nitrogen fluid infusion jar outside is provided with the liquid level display moreover, can look over liquid nitrogen volume at any time. Certainly, if the temperature sensor detects that the temperature in the liquid nitrogen tank can not meet the requirement, the system display controller controls the low-temperature refrigerant to cool the liquid nitrogen tank to the temperature of minus 110 ℃ to minus 150 ℃.
Further, a first cover plug is installed on the liquid nitrogen tank, a long-strip-shaped slotted hole is formed in the first cover plug, a second cover plug is installed at the slotted hole, and a magnetic part is arranged at the top of the second cover plug;
the auxiliary opening and closing device comprises a first electric rotating device, an electric lifting device, a second electric rotating device and an electromagnet, the first electric rotating device is installed on the system frame, the electric lifting device is installed at the rotary driving end of the top of the first electric rotating device, a first transverse rod is arranged on the electric lifting device, the free end of the first transverse rod is provided with the second electric rotating device, the position of the first transverse rod, which is close to the free end of the first transverse rod, is provided with the electromagnet, the rotary driving end of the lower part of the second electric rotating device is matched with the first cover plug, and the electromagnet is matched with the magnetic piece.
The beneficial effect of adopting the further scheme is that: utilize first lid to fill in sealed liquid nitrogen container, utilize the second lid to fill in and realize getting of cryopreserving pipe and take, avoid the too much loss of air conditioning.
Furthermore, a second cross rod is arranged at the rotary driving end at the lower part of the second electric rotating device, two ends of the lower part of the second cross rod are respectively provided with a limiting column, and a limiting groove matched with the limiting column is formed in the center of the top end face of the first cover plug.
The beneficial effect of adopting the further scheme is that: through the cooperation of restriction post and spacing groove, realize the rotational positioning of electric rotary device two pairs of first lid stopper.
Further, the sample transportation device comprises an X-axis translation driving part, a Y-axis translation driving part and a Z-axis translation driving part, the Y-axis translation driving part is installed on the X-axis translation driving part, the Z-axis translation driving part is installed on the Y-axis translation driving part, and the vacuum generation device is installed on the Z-axis translation driving part.
The beneficial effect of adopting the further scheme is that: can realize vacuum generating device omnidirectional movement, deposit the pipe to freezing of different angles and realize snatching.
Further, vacuum generating device includes air compressor, vacuum generating equipment, vacuum suction pipe and negative pressure pipeline, air compressor with vacuum generating equipment intercommunication, vacuum generating equipment is connected with system display controller, vacuum generator pass through the negative pressure pipeline with vacuum suction pipe intercommunication, the vertical arrangement of vacuum suction pipe and its lower extreme are equipped with vacuum suction head, vacuum suction head with tubular metal resonator upper end inner chamber looks adaptation.
The sample transfer device comprises an electric translation device and a sample transfer barrel, and the electric translation device is arranged in the system frame and drives the sample transfer barrel to a set position.
Furthermore, a shell is arranged outside the system frame, the shell and the system frame form a cavity, an automatic table board is arranged in the cavity, and the sample conveying device and the auxiliary opening and closing device are respectively arranged on the automatic table board; the automatic table board divides the cavity into an upper closed inner cavity and a lower semi-closed inner cavity, a dehumidifier is installed in the upper closed inner cavity, and the lower semi-closed inner cavity is provided with a code scanning device for scanning two-dimensional codes on the cryopreservation tube to identify and store sample information.
The beneficial effect of adopting the further scheme is that: the full-automatic sample storage, sample information collection and recording and informatization real-time monitoring can be realized.
Drawings
Fig. 1 is a schematic perspective view of an ultra-low temperature storage system of the present invention;
FIG. 2 is a schematic top view of the ultra-low temperature storage system of the present invention;
FIG. 3 is a schematic structural view of the liquid nitrogen container of the present invention;
FIG. 4 is a cross-sectional view taken along plane A-A of FIG. 3;
FIG. 5 is an enlarged view of the portion A of FIG. 4;
FIG. 6 is an enlarged view of the portion B in FIG. 4;
fig. 7 is a schematic perspective view of a sample transport device in an ultra-low temperature storage system according to the present invention;
fig. 8 is a schematic perspective view of the vacuum generator of the present invention;
fig. 9 is a schematic perspective view of an auxiliary opening and closing device in the ultra-low temperature storage system of the present invention;
fig. 10 is a schematic perspective view of a sample transfer device in an ultra-low temperature storage system according to the present invention;
fig. 11 is a schematic perspective view of the system frame of the present invention;
fig. 12 is a schematic perspective view of the system display controller according to the present invention.
In the drawings, the components represented by the respective reference numerals are listed below:
100. a system frame; 101. a housing; 102. an automated table top;
200. an ultra-low temperature storage device; 201. a liquid nitrogen tank; 202. a first cap plug; 203. a second cap plug; 204. A limiting groove; 205. a magnetic member; 206. a metal disc; 207. a metal tube; 208. a connecting section; 209. An inner edge;
300. an auxiliary opening and closing device; 301. a first electric rotating device; 302. a second electric rotating device; 303. An electric lifting device; 304. a first cross bar; 305. a second cross bar; 306. a limiting column; 307. an electromagnet;
400. a vacuum generating device; 401. a vacuum generating device; 402. a vacuum suction tube; 403. a negative pressure pipeline; 404. a vacuum suction head; 405. a connecting plate;
500. a sample transport device; 501. an X-axis translation drive section; 502. a Y-axis translation drive section; 503. A Z-axis translation drive section;
600. a sample transfer device; 601. an electric translation device; 602. the sample is transferred to a storage barrel;
700. a system display controller; 701. an electric cabinet; 702. a display; 800. a dehumidifier.
Detailed Description
The principles and features of the present invention are described below in conjunction with the following drawings, the examples given are only intended to illustrate the present invention and are not intended to limit the scope of the present invention.
As shown in fig. 1 to 12, an ultra-low temperature storage system of the present embodiment includes a system frame 100, and an ultra-low temperature storage device 200, an auxiliary opening and closing device 300, a vacuum generating device 400, and a sample transport device 500 mounted on the system frame 100; the auxiliary opening and closing device 300 is matched with the cover plug of the ultra-low temperature storage device 200 to expose the cryopreservation tube, and the vacuum generating device 400 is connected with the sample transport device 500 and moves to a preset position under the driving of the sample transport device 500 to take and place the cryopreservation tube; the ultra-low temperature storage device 200 comprises a liquid nitrogen tank 201, a metal disc 206 and a plurality of metal tubes 207, wherein the metal disc 206 is mounted in the liquid nitrogen tank 201, a plurality of through holes which are communicated up and down are distributed on the metal disc 206, and the plurality of metal tubes 207 are correspondingly inserted into the plurality of through holes of the metal disc 206 one by one and are suspended in the liquid nitrogen tank 201.
The ultralow temperature storage system of the embodiment can automatically take samples, avoid excessive external interference, improve the efficiency and the space utilization rate, and improve the safety and reliability of storage and sampling; the utility model discloses a densely covered formula alloy pipe subassembly stores and freezes the deposit pipe, convenient manufacturing, low cost.
The liquid nitrogen tank 201 of the present embodiment has a customized right circular cylindrical structure, and the metal plate 206 has a disc-shaped structure.
As shown in fig. 4-5, the outer side wall of the metal tube 207 of this embodiment near the upper end is provided with a ring-shaped shoulder, and the metal tube 207 is erected on the metal disc 206 through the ring-shaped shoulder. That is, the portion of the metal tube 207 near the upper end is a connection section 208, the inner diameter of the connection section 208 is larger than the inner diameter of the metal tube 207, and the outer diameter of the connection section 208 is larger than the outer diameter of the metal tube 207. Specifically, the upper end opening of the connecting section 208 is a bell mouth, the middle part is a straight cylinder structure, and the lower end is connected to the metal tube after closing up. The metal pipe can be suspended on the metal disc by arranging the annular circular bead on the outer side wall of the metal pipe, and the metal pipes with different lengths can be arranged as required. In addition, as shown in fig. 6, a ring-shaped inner edge 209 is further provided at a position of the metal pipe 207 near the lower end, so that the frozen pipe stored in the metal pipe 207 does not leak out of the metal pipe. The lower part of the metal pipe 207 may be submerged in the liquid nitrogen tank 201 or may be located above the liquid nitrogen.
In a preferred embodiment of this embodiment, the metal plate 206 is an aluminum plate, and the metal tube 207 is an aluminum alloy tube formed by stamping, machining or casting. The aluminum alloy pipe not only can be used for storing the frozen pipes, but also can be used for transferring the frozen pipes. A plurality of freezing pipes which are sequentially arranged up and down can be placed in each aluminum alloy pipe. The aluminum alloy pipe is evenly arranged on the aluminum plate to form the densely distributed alloy pipe assembly, the aluminum alloy pipe is inserted into the aluminum plate, and the installation is completed, so that the aluminum alloy pipe is simple, practical and convenient to process and manufacture.
A further scheme of this embodiment is that a temperature sensor or/and a liquid level sensor are/is arranged in the liquid nitrogen tank 201, and the temperature sensor or/and the liquid level sensor are/is respectively connected with the system display controller 700; the external refrigeration assembly comprises a liquid nitrogen replenishing tank and an automatic liquid replenishing system, the automatic liquid replenishing system is respectively connected with the liquid nitrogen replenishing tank and the liquid nitrogen tank 201, and the system display controller 700 is connected with the automatic liquid replenishing system and is used for controlling the automatic liquid replenishing system to convey liquid nitrogen in the liquid nitrogen replenishing tank into the liquid nitrogen tank 201; or/and the external refrigeration component comprises a cryogenic refrigerator, and the system display controller 700 is connected with the cryogenic refrigerator. The temperature sensor can monitor the internal temperature of the liquid nitrogen tank in real time, the storage reliability of the cryopreservation pipe can be ensured, the liquid level sensor can monitor the amount of liquid nitrogen in the liquid nitrogen tank, and the liquid nitrogen tank can be automatically refrigerated through the external refrigeration assembly; when level sensor detected need supply liquid nitrogen in the liquid nitrogen jar, liquid nitrogen of liquid nitrogen fluid infusion jar can also set up level sensor in the liquid nitrogen fluid infusion jar automatically supply liquid nitrogen jar, when level sensor in the liquid nitrogen fluid infusion jar detected the liquid nitrogen not enough, can automatic alarm remind the replenishment, the liquid nitrogen fluid infusion jar outside is provided with the liquid level display moreover, can look over liquid nitrogen volume at any time. Certainly, if the temperature sensor detects that the temperature in the liquid nitrogen tank can not meet the requirement, the system display controller controls the low-temperature refrigerant to cool the liquid nitrogen tank to the temperature of minus 110 ℃ to minus 150 ℃.
As shown in fig. 1 to 4, a first cover plug 202 is installed on the liquid nitrogen tank 201 of this embodiment, a long-strip-shaped slot hole is formed in the first cover plug 202, a second cover plug 203 is installed at the slot hole, and a magnetic member 205 is installed at the top of the second cover plug 203; the auxiliary opening and closing device 300 comprises a first electric rotating device 301, an electric lifting device 303, a second electric rotating device 302 and an electromagnet 307, wherein the first electric rotating device 301 is installed on the system frame 100, the electric lifting device 303 is installed at a rotating driving end at the top of the first electric rotating device 301, a first cross rod 304 is arranged on the electric lifting device 303, the second electric rotating device 302 is arranged at the free end of the first cross rod 304, the electromagnet 307 is arranged at the position, close to the free end, of the first cross rod 304, the rotating driving end at the lower part of the second electric rotating device 302 is matched with the first cover plug 202, and the electromagnet 307 is matched with the magnetic piece 205. Utilize first lid to fill in sealed liquid nitrogen container, utilize the second lid to fill in and realize getting of cryopreserving pipe and take, avoid the too much loss of air conditioning.
The first cover plug 202 of the embodiment is used for sealing the liquid nitrogen tank 201, the first cover plug 202 is made of foamed polyurethane and stainless steel materials, and the pore characteristics of the foamed polyurethane can seal cold air in the liquid nitrogen tank and prevent the internal air pressure from being too high and being discharged. The material of the second cover plug 203 is the same as that of the first cover plug 202, and the top magnetic member 205 of the second cover plug 203 can be attracted by an electromagnet for opening the second cover plug 203.
As shown in fig. 9, a second cross bar 305 is disposed at the rotation driving end of the lower portion of the second electric rotating device 302 of this embodiment, two ends of the lower portion of the second cross bar 305 are respectively disposed with a limiting post 306, and a limiting groove 204 adapted to the limiting post 306 is disposed at the center of the top end surface of the first cap plug 202. Through the cooperation of restriction post and spacing groove, realize the rotational positioning of electric rotary device two pairs of first lid stopper.
As shown in fig. 1 and 7, the sample transport apparatus 500 of the present embodiment includes an X-axis translation driving part 501, a Y-axis translation driving part 502, and a Z-axis translation driving part 503, the Y-axis translation driving part 502 is mounted on the X-axis translation driving part 501, the Z-axis translation driving part 503 is mounted on the Y-axis translation driving part 502, and the vacuum generating device 400 is mounted on the Z-axis translation driving part 503. Can realize vacuum generating device omnidirectional movement, to the frozen pipe realization of different angles snatch, move operations such as transfer. The connecting plate 405 is installed on the Z-axis translation driving portion 503, the connecting plate 405 includes a fixing plate and an L-shaped plate, the fixing plate is fixed on the Z-axis translation driving portion 503, the L-shaped plate is fixed on the fixing plate, and the vacuum suction pipe 402 vertically penetrates through and is fixed on the L-shaped plate.
The X-axis translation driving portion 501 and the Y-axis translation driving portion 502 of this embodiment can both adopt a synchronous belt structure and adopt a stepping motor to drive, can adopt a profile and guide rail structure to guide, and can also increase a grating ruler to improve positioning accuracy. The Z-axis translation driving part 503 can adopt a screw structure and a stepping motor for driving, can adopt a profile and guide rail structure for guiding, and can also increase a grating ruler to improve the positioning accuracy.
As shown in fig. 8, the vacuum generating apparatus 400 of this embodiment includes an air compressor, a vacuum generating device 401, a vacuum suction pipe 402 and a negative pressure pipeline 403, the air compressor is communicated with the vacuum generating device 401, the vacuum generating device 401 is connected with a system display controller 700, the vacuum generating device 401 is communicated with the vacuum suction pipe 402 through the negative pressure pipeline 403, the vacuum suction pipe 402 is vertically arranged and a vacuum suction head 404 is arranged at a lower end of the vacuum suction pipe 402, and the vacuum suction head 404 is adapted to an inner cavity at an upper end of the metal pipe 207. The vacuum generator 401 of this embodiment may be a vacuum generator with a pressure switch, and the vacuum generator is electrically connected to the system display controller 700, and generates a vacuum negative pressure effect by controlling the compressed air provided by the air compressor. When the vacuum suction head 404 on the vacuum suction pipe 402 sucks the cryopreservation pipe, the pressure switch can detect the pressure change, so that the cryopreservation pipe is judged to be successfully sucked. Vacuum generating device 401 can also select for use the vacuum pump of taking vacuum monitoring, and the vacuum pump passes through negative pressure pipeline and vacuum suction tube to be connected, realizes the absorption and put down of cryopreserving pipe. Wherein, the vacuum suction head 404 and the vacuum suction pipe 402 are made of low temperature resistant materials respectively.
As shown in fig. 1 and 10, the ultra-low temperature storage system of the present embodiment further includes a sample transfer device 600, wherein the sample transfer device 600 includes a motorized translation device 601 and a sample transfer barrel 602, and the motorized translation device 601 is installed in the system frame 100 and drives the sample transfer barrel 602 to a set position. The sample transferring barrel 602 can adopt a commercially available vacuum heat-insulating barrel, a transferring tray of a freezing tube is arranged at the barrel mouth of the sample transferring barrel 602, a temperature conduction device is arranged at the bottom of the sample transferring barrel, liquid nitrogen is added into the sample transferring barrel during use, and the freezing tube is arranged on the transferring tray. The electric translation device 601 may be a screw structure, and may be driven by a stepping motor, or may be guided by a profile and guide rail structure.
As shown in fig. 1 and fig. 11, a casing 101 is provided outside the system frame 100, the casing 101 and the system frame 100 form a cavity, an automation table 102 is provided in the cavity, and the sample transportation device 500 and the auxiliary opening and closing device 300 are respectively mounted on the automation table 102; the automatic table-board 102 divides the cavity into an upper closed inner cavity and a lower semi-closed inner cavity, a dehumidifier 800 is installed in the upper closed inner cavity, and a code scanning device for scanning two-dimensional codes on the cryopreservation tube to identify and store sample information is arranged in the lower semi-closed inner cavity. The full-automatic sample storage, sample information collection and recording and informatization real-time monitoring can be realized. An automatic opening and closing door is arranged at the position of the shell 101 corresponding to the sample transfer device 600.
As shown in fig. 12, the system display controller 700 of this embodiment includes an electric cabinet 701 and a display 702, and the system display controller 700 may adopt a windows system or an android system. The system display controller is electrically connected with the motors and the sensors of all the devices.
The working process of the ultra-low temperature storage system of this embodiment does, when the pipe is deposited to needs storage freezing, will freeze and deposit the pipe and put into sample transfer and deposit the bucket earlier, utilize electronic translation device to transfer the sample and deposit the bucket and carry the lower semi-closed inner chamber that enters into in the shell, sample conveyer drives the vacuum suction pipe and removes to freeze and deposit the pipe top, and simultaneously, supplementary device that opens and shuts removes directly over the second stopper, the electro-magnet adsorbs the magnetic part on the second stopper, and place the second stopper automatic mesa relevant position, after the completion, supplementary spacing post on the device upper cross rod two that opens and shuts and the spacing groove adaptation on the first stopper, utilize electronic rotary device two to rotate first stopper, make the slotted hole on the first stopper rotate to the position that needs placed and freeze and deposit the pipe. Z axle translation drive division drives the vacuum suction tube and absorbs and freezes and deposit the pipe, removes to automatic mesa and sweeps yard device top, accomplishes and sweeps yard discernment, confirms errorlessly back through system display controller, and sample conveyer drives and freezes to deposit the pipe and remove to liquid nitrogen tank top, and Z axle translation drive division drives the vacuum suction tube, will freeze and deposit the pipe and put into the aluminium alloy pipe in the liquid nitrogen tank intraductally, accomplish and freeze and deposit of depositing the pipe. And after all the freezing pipes are completely stored, the sample conveying device automatically returns. The auxiliary opening and closing device rotates the first cover plug to return to the initial position, and the auxiliary opening and closing device adsorbs the second cover plug and moves to the position right above the first cover plug groove hole for sealing. Meanwhile, the sample transfer device in the shell extends out, and after the sample transfer barrel is taken away, the sample transfer device enters the shell, and lofting is completed. When the cryopreserved pipe was taken out to needs, the automatic door that opens and shuts on the shell was opened, and the electronic translation device of sample transfer device stretches out, puts into electronic translation device with sample transfer bucket, and sample transfer device enters into the cavity in the shell, and the automatic door that opens and shuts on the shell is closed. Supplementary device that opens and shuts removes directly over the second stopper, the electro-magnet adsorbs the second stopper and places the fixed position of automatic mesa, then supplementary device that opens and shuts rotates first stopper, make slotted hole on the first stopper rotate to the storage position that freezes the pipe that needs take out, Z axle translation drive division drives vacuum suction tube and absorbs other freezes and deposits the pipe in target freezes and deposits pipe top, put into the transfer aluminum alloy pipe that is used for the transfer, it is located the top until the target freezes deposits the pipe, then absorb the target and freeze and deposit the pipe again, it sweeps a yard device top to remove to automatic mesa, the sign indicating number discernment is swept in the completion, confirm after having no mistake, put back the normal position with freezing of depositing the intraductal pipe of transfer aluminum alloy. The completion freezes the back of taking out of depositing the pipe, and the sample conveyer is automatic to be playback, and the supplementary device that opens and shuts rotates first lid stopper and returns to initial position, and the supplementary device that opens and shuts adsorbs the second lid stopper to remove and seal directly over first lid stopper slotted hole. Meanwhile, an automatic opening and closing door on the shell is opened, the sample transfer device extends out of the automatic opening and closing door, a worker takes away the sample transfer barrel, the sample transfer device enters the inner cavity of the shell, the automatic opening and closing door on the shell is closed, and sampling is completed.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", and the like, indicate the orientation or positional relationship indicated based on the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
In the present application, unless expressly stated or limited otherwise, the first feature may be directly on or directly under the second feature or indirectly via intermediate members. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.
Although embodiments of the present invention have been shown and described, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art without departing from the scope of the present invention.
Claims (10)
1. An ultra-low temperature storage system is characterized by comprising a system frame, and an ultra-low temperature storage device, an auxiliary opening and closing device, a vacuum generating device and a sample transportation device which are arranged on the system frame; the auxiliary opening and closing device is matched with a cover plug of the ultralow-temperature storage device to expose the cryopreservation tube, and the vacuum generating device is connected with the sample conveying device and moves to a preset position under the driving of the sample conveying device to take and place the cryopreservation tube; the ultra-low temperature storage device comprises a liquid nitrogen tank, a metal disc and a plurality of metal tubes, wherein the metal disc and the metal tubes are arranged in the liquid nitrogen tank, a plurality of through holes which are communicated from top to bottom are distributed on the metal disc, and the metal tubes are inserted into the through holes of the metal disc in a one-to-one correspondence manner and are suspended in the liquid nitrogen tank.
2. The ultra-low temperature storage system of claim 1, wherein said metal tube has a ring-shaped shoulder on an outer side wall thereof near an upper end thereof, said metal tube being bridged on said metal plate by said ring-shaped shoulder.
3. The ultra-low temperature storage system of claim 1, wherein said metal plate is an aluminum plate and said metal tube is an aluminum alloy tube stamped or machined or cast.
4. The ultra-low temperature storage system of claim 1, further comprising an external refrigeration assembly, wherein a temperature sensor or/and a liquid level sensor are arranged in the liquid nitrogen tank, and the temperature sensor or/and the liquid level sensor are respectively connected with a system display controller;
the external refrigeration assembly comprises a liquid nitrogen replenishing tank and an automatic liquid replenishing system, the automatic liquid replenishing system is respectively connected with the liquid nitrogen replenishing tank and the liquid nitrogen tank, and the system display controller is connected with the automatic liquid replenishing system; and the external refrigeration assembly comprises a low-temperature refrigerator, and the system display controller is connected with the low-temperature refrigerator.
5. The ultra-low temperature storage system as claimed in claim 1, wherein a first cover plug is mounted on the liquid nitrogen tank, a slotted hole with a long strip shape is formed in the first cover plug, a second cover plug is mounted at the slotted hole, and a magnetic part is arranged at the top of the second cover plug;
the auxiliary opening and closing device comprises a first electric rotating device, an electric lifting device, a second electric rotating device and an electromagnet, the first electric rotating device is installed on the system frame, the electric lifting device is installed at the rotary driving end of the top of the first electric rotating device, a first transverse rod is arranged on the electric lifting device, the free end of the first transverse rod is provided with the second electric rotating device, the position of the first transverse rod, which is close to the free end of the first transverse rod, is provided with the electromagnet, the rotary driving end of the lower part of the second electric rotating device is matched with the first cover plug, and the electromagnet is matched with the magnetic piece.
6. The ultra-low temperature storage system of claim 5, wherein a second cross bar is disposed at a rotary driving end of a lower portion of the second electrical rotary device, two ends of a lower portion of the second cross bar are respectively provided with a limiting post, and a central position of a top end surface of the first lid plug is provided with a limiting groove adapted to the limiting post.
7. The ultra-low temperature storage system of claim 1, wherein the sample transporter includes an X-axis translational drive portion, a Y-axis translational drive portion and a Z-axis translational drive portion, the Y-axis translational drive portion being mounted on the X-axis translational drive portion, the Z-axis translational drive portion being mounted on the Y-axis translational drive portion, the vacuum generator being mounted on the Z-axis translational drive portion.
8. An ultra-low temperature storage system as claimed in claim 1, wherein the vacuum generating device comprises an air compressor, a vacuum generating device, a vacuum suction pipe and a negative pressure pipeline, the air compressor is connected with the vacuum generating device, the vacuum generating device is connected with the system display controller, the vacuum generating device is connected with the vacuum suction pipe through the negative pressure pipeline, the vacuum suction pipe is vertically arranged and the lower end of the vacuum suction pipe is provided with a vacuum suction head, and the vacuum suction head is matched with the inner cavity at the upper end of the metal pipe.
9. The ultra-low temperature storage system of claim 1, further comprising a sample relay device, said sample relay device comprising a motorized translation device and a sample transfer barrel, said motorized translation device mounted within said system frame and driving said sample transfer barrel to a set position.
10. The ultra-low temperature storage system of claim 1, wherein the system frame is externally provided with a housing, the housing and the system frame form a cavity, an automatic table is arranged in the cavity, and the sample transportation device and the auxiliary opening and closing device are respectively mounted on the automatic table; the automatic table board divides the cavity into an upper closed inner cavity and a lower semi-closed inner cavity, a dehumidifier is installed in the upper closed inner cavity, and the lower semi-closed inner cavity is provided with a code scanning device for scanning two-dimensional codes on the cryopreservation tube to identify and store sample information.
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| CN202022393723.6U CN213631099U (en) | 2020-10-23 | 2020-10-23 | Ultralow temperature storage system |
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| CN202022393723.6U CN213631099U (en) | 2020-10-23 | 2020-10-23 | Ultralow temperature storage system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116555030A (en) * | 2023-06-12 | 2023-08-08 | 北京康泰联和国际生物科技有限公司 | Storage equipment based on umbilical cord mesenchymal stem cell culture |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116555030A (en) * | 2023-06-12 | 2023-08-08 | 北京康泰联和国际生物科技有限公司 | Storage equipment based on umbilical cord mesenchymal stem cell culture |
| CN116555030B (en) * | 2023-06-12 | 2023-12-08 | 北京康泰联和国际生物科技有限公司 | Storage equipment based on umbilical cord mesenchymal stem cell culture |
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