CN214881582U

CN214881582U - Automatic stirring cell culture fermentation cylinder

Info

Publication number: CN214881582U
Application number: CN202120590713.3U
Authority: CN
Inventors: 张桂涛; 刘友桃; 陈亮; 张祥涛; 陈静山
Original assignee: Guangzhou Taili Biomedical Technology Co ltd
Current assignee: Guangzhou Taili Biomedical Technology Co ltd
Priority date: 2021-03-17
Filing date: 2021-03-17
Publication date: 2021-11-26
Anticipated expiration: 2031-03-17

Abstract

The utility model discloses an automatic stirring cell culture fermentation tank, which comprises a support frame, a driving mechanism arranged below one side of the support frame, and a fermentation tank which is arranged on the support frame and can adjust and swing through the driving mechanism, wherein the fermentation tank comprises a tank body, a cover body arranged at the top of the tank body, and a stirring motor fixed with the cover body through screws, fixed shafts are arranged on two sides of the upper end of the tank body, ball bearing seats are arranged on the fixed shafts, an iron frame is fixed at the bottom of the tank body through welding, and rollers are arranged on the iron frame; through driving motor drive cam and gyro wheel contact, can make the fermentation cylinder to the swing of one side, the agitator motor of installation on the cooperation fermentation cylinder for the fermentation cylinder carries out automatic swing at automatic stirring in-process, can make the mixture of cell and culture solution more even, more is favorable to the proliferation growth of cell, improves the cell activity.

Description

Automatic stirring cell culture fermentation cylinder

Technical Field

The utility model particularly relates to an automatic stirring cell culture fermentation cylinder.

Background

Due to the rapid development of the biological engineering technology, the genetic engineering product medicines, such as GMCS, GCSF, TPO, EGF and the like, are officially put into clinical medication, bring great social benefits and bring considerable economic benefits to pharmaceutical enterprises.

Fermentation is an important link in bioengineering, and fermentation equipment is important equipment of bioengineering corollary equipment. The aim of researching fermentation equipment is to provide optimal growth and propagation conditions for engineering bacteria or engineering cells, namely, provide optimal external conditions such as temperature, pH value (pH value), stirring speed and dissolved oxygen content, and maximally produce various biochemical substances required by people in the form of inclusion bodies or supernatant after the engineering bacteria or the engineering cells are grown and propagated.

Disclosure of Invention

In view of this, the utility model aims at providing a make the mixture of cell and culture solution more even, more be favorable to cell proliferation to grow, improve the automatic stirring cell culture fermentation cylinder of cell activity.

In order to solve the technical problem, the technical scheme of the utility model is that:

the utility model provides an automatic stirring cell culture fermentation cylinder, includes the support frame, installs actuating mechanism below support frame one side, and place on the support frame, and adjust wobbling fermentation cylinder through actuating mechanism, the fermentation cylinder is including a jar body, installs the lid at jar body top, and with the lid passes through the agitator motor of fix with screw, the fixed axle is installed to the upper end both sides of the jar body, and install ball bearing frame on the fixed axle, the bottom of the jar body still has the iron stand through welded fastening, and install the gyro wheel on the iron stand.

Preferably, the cover body is fastened and fixed with the tank body.

Preferably, the output end of the stirring motor penetrates through the cover body and extends to the inside of the tank body, a stirring shaft is installed at the output end of the stirring motor, and an X-shaped stirring frame is fixedly installed on the stirring shaft through a pin key.

Preferably, the support frame comprises a support frame body and a mounting seat arranged at the upper end of the support frame body and used for placing the fermentation tank.

Preferably, the driving mechanism comprises a driving motor, and a base which is fixed with the supporting frame through a screw and used for supporting and installing the driving motor.

Preferably, a cam is further mounted on the driving motor, and the cam is in contact with the roller.

The utility model discloses technical effect mainly embodies in following aspect: through driving motor drive cam and gyro wheel contact, can make the fermentation cylinder to the swing of one side, the agitator motor of installation on the cooperation fermentation cylinder for the fermentation cylinder carries out automatic swing at automatic stirring in-process, can make the mixture of cell and culture solution more even, more is favorable to the proliferation growth of cell, improves the cell activity.

Drawings

FIG. 1 is a schematic diagram of an automatic stirred cell culture fermenter according to the present invention;

FIG. 2 is a schematic view of the fermenter of FIG. 1.

Detailed Description

The following detailed description of the embodiments of the present invention is made with reference to the accompanying drawings, so that the technical solution of the present invention can be more easily understood and grasped.

In the present embodiment, it should be understood that the terms "middle", "upper", "lower", "top", "right side", "left end", "above", "back", "middle", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description of the present invention, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.

In the present embodiment, if the connection or fixing manner between the components is not specifically described, the connection or fixing manner may be a bolt fixing manner, a pin connecting manner, or the like, which is commonly used in the prior art, and therefore, details thereof are not described in the present embodiment.

Examples

The utility model provides an automatic stirring cell culture fermentation cylinder, as shown in figure 1, includes support frame 1, installs actuating mechanism 2 of support frame 1 one side below, and place on the support frame 1, and adjust wobbling fermentation cylinder 3 through actuating mechanism 2, support frame 1 is including supporting support body 11, sets up support body 11 upper end, be used for placing fermentation cylinder 3's mount pad 12, mount pad 12 is used for clamping ball bearing frame 312 for fermentation cylinder 3 places behind support frame 1, can carry out the horizontal hunting through ball bearing frame 312. The driving mechanism 2 comprises a driving motor 21 and a base 22 which is fixed with the supporting frame 1 through screws and used for supporting and installing the driving motor 21. Still install cam 211 on driving motor 21, cam 211 with gyro wheel 314 contact, when in actual use, driving motor 21 drives cam 211 and rotates, and cam 211 can drive fermentation cylinder 3 to the swing of one side when rotatory, rocks when stirring the cell culture liquid in the fermentation cylinder 3, is favorable to improving the activity of cell culture liquid.

As shown in fig. 2, the fermentation tank 3 includes a tank 31, a cover 32 mounted on the top of the tank 31, and a stirring motor 33 fixed to the cover 32 by screws, wherein fixing shafts 311 are mounted on two sides of the upper end of the tank 31, ball bearing blocks 312 are mounted on the fixing shafts 311, an iron frame 313 is fixed to the bottom of the tank 31 by welding, and rollers 314 are mounted on the iron frame 313. The cover 32 is fastened and fixed with the tank 31, and specifically, the cover 32 can be prevented from loosening due to vibration when the stirring motor 33 operates. The output end of the stirring motor 33 penetrates through the cover body 32 and extends into the tank body 31, a stirring shaft 331 is installed at the output end of the stirring motor 33, and an X-shaped stirring frame 332 is fixedly installed on the stirring shaft 331 through a pin key.

Of course, the above is only a typical example of the present invention, and besides, the present invention can also have other various specific embodiments, and all technical solutions adopting equivalent replacement or equivalent transformation are all within the scope of the present invention as claimed.

Claims

1. The utility model provides an automatic stirring cell culture fermentation cylinder, includes the support frame, installs the actuating mechanism of support frame one side below, and place on the support frame, and adjust wobbling fermentation cylinder, its characterized in that through actuating mechanism: the fermentation cylinder is including a jar body, install the lid at jar body top, and with the lid passes through the agitator motor of fix with screw, the fixed axle is installed to the upper end both sides of the jar body, and install ball bearing frame on the fixed axle, the bottom of the jar body still has the iron stand through welded fastening, and install the gyro wheel on the iron stand.

2. The automated stirred cell culture fermenter of claim 1, wherein: the cover body is fixedly buckled with the tank body.

3. The automated stirred cell culture fermenter of claim 1, wherein: the output of agitator motor runs through the lid and extends to jar internal portion to install the (mixing) shaft on agitator motor's output, there is the stirring frame of X shape on the (mixing) shaft through cotter fixed mounting.

4. The automated stirred cell culture fermenter of claim 1, wherein: the support frame is in including supporting the support body, set up support body upper end, be used for placing the mount pad of fermentation cylinder.

5. The automated stirred cell culture fermenter of claim 1, wherein: the driving mechanism comprises a driving motor and a base which is fixed with the supporting frame through screws and used for supporting and installing the driving motor.

6. An automated stirred cell culture fermenter according to claim 5, wherein: and the driving motor is also provided with a cam, and the cam is in contact with the roller.