CN214704036U - Vaginal suppository detection device - Google Patents

Abstract

The utility model relates to a pessary detection device includes: operating the body; the light-emitting piece is arranged in the operation body and used for generating light; the probe is provided with a first end and a second end which are oppositely arranged, and the first end is matched and connected with one end of the operation body; and a light-diffusing member coupled to the second end; the probe comprises an operation body, a probe and a light-emitting piece, wherein one end of the operation body, which is close to the probe, is provided with a first light conduction part, and light generated by the light-emitting piece can be conducted to the first end of the probe through the first light conduction part; the probe is provided with a second light transmission part connected between the first end and the second end, light transmitted to the first end can be transmitted to the second end through the second light transmission part, and the light scattering part is used for scattering the light transmitted to the second end. Through this pessary detection device, can detect the pessary of little volume or the vagina depths in experimental animals vagina inside easily to the detection efficiency and the detection precision to experimental animals pessary have been improved.

Description

Vaginal suppository detection device

Technical Field

The utility model relates to an experimental animals diagnosis technical field of gestation especially relates to pessary detection device.

Background

The experimental animal is an animal engaged in scientific research, teaching, production, detection and scientific experiments thereof, is widely applied to aspects of biomedicine, medicine research and development, teaching experiments, biological detection and the like, and plays an important role in life science research. Because the gene similarity of the mouse and the human is 99 percent, and the breeding of the mouse are relatively cheap and the breeding is rapid. At present, about 9 mice out of 10 experimental animals are used, and the application fields include immunology, oncology, physiology, pathology, embryology and reproduction, and the application in neuroscience is increasing, and the mice are also the pronouns of experimental animals.

In the work of research on reproduction, before various experimental operations are carried out by using fertilized eggs and embryos of mice, whether the male and female cage mice on the day mate successfully needs to be determined. At present, methods for identifying the success or failure of mouse cage mating mainly comprise a mouse vaginal smear method and a mouse vaginal suppository examination method.

However, when the method is used for detecting whether the vaginal pessary exists in the vagina of the mouse, the detection efficiency is low, and the accuracy is not high.

SUMMERY OF THE UTILITY MODEL

Therefore, it is necessary to provide a vaginal suppository detection device capable of improving detection efficiency and detection accuracy, which is aimed at the problems of low detection efficiency and low detection accuracy when a mouse vaginal suppository is detected at present.

According to an aspect of the present application, there is provided a vaginal suppository detection device for detecting the presence or absence of a vaginal suppository in a vagina of a laboratory animal, the vaginal suppository detection device comprising:

operating the body;

the light-emitting piece is arranged in the operation body and used for generating light;

the probe is provided with a first end and a second end which are oppositely arranged, and the first end is matched and connected with one end of the operation body; and

a diffuser coupled to the second end;

the operating body is provided with a first light transmission part at one end close to the probe, and light generated by the light-emitting piece can be transmitted to the first end of the probe through the first light transmission part;

the probe is provided with a second light transmission part connected between the first end and the second end, light transmitted to the first end can be transmitted to the second end through the second light transmission part, and the light scattering part is used for scattering the light transmitted to the second end.

In one embodiment, the radial dimension of the probe is configured to gradually decrease from the first end to the second end.

In one embodiment, the diffuser is ellipsoidal.

In one embodiment, the radial dimension of the operating body is configured to gradually decrease toward the first end and form a light-gathering portion.

In one embodiment, the light emitting member is disposed in the light collecting portion.

In one embodiment, the vaginal suppository detection device further comprises an energy source member disposed within the operating body for providing light-generating energy to the light emitting member.

In one embodiment, the pessary detecting device further comprises a control member, wherein the control member is coupled to the operation body and is in signal connection with the energy source member.

In one embodiment, the pessary testing device further comprises a cleaning member fixed to an end of the operating body away from the probe.

In one embodiment, the vaginal suppository detecting device further comprises a positioning piece, the positioning piece is detachably connected to one end, far away from the probe, of the operating body, and the cleaning piece is fixed on the operating body through the positioning piece.

In one embodiment, a positioning opening is formed in one side of the positioning piece, the positioning piece is provided with a positioning cavity communicated with the positioning opening, and the cleaning piece is installed in the positioning cavity and at least partially protrudes out of the positioning opening.

Above-mentioned pessary detection device stretches into the probe in experimental animals's vagina, and the light that will transmit the probe through the astigmatic spare is inside scattering in experimental animals vagina for the operator can easily observe the less pessary of volume, perhaps embeds darker pessary. Therefore, the detection efficiency and the detection precision of the pessary of the experimental animal can be improved.

Drawings

Fig. 1 is a schematic structural diagram of a vaginal embolus detecting device in an embodiment of the present application;

FIG. 2 is a flow chart illustrating the detection of the vaginal embolus detecting device shown in FIG. 1;

fig. 3 is a flow chart of the detection of the preferred embodiment of the vaginal embolus detection device shown in fig. 1.

Detailed Description

In order to make the above objects, features and advantages of the present invention more comprehensible, embodiments of the present invention are described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. The present invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein, as those skilled in the art will be able to make similar modifications without departing from the spirit and scope of the present invention.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", and the like, indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

In the present application, unless expressly stated or limited otherwise, the first feature may be directly on or directly under the second feature or indirectly via intermediate members. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.

In order to facilitate understanding of the technical solution of the present invention, prior to the detailed explanation, the prior method for detecting the pessary of the experimental animal will be explained first.

Female mice after mating will develop a mating plug, also known as a pessary, within the vagina. The mouse vaginal suppository is formed by coagulation reaction of protein in seminal plasma of a male mouse in the vagina of a female mouse, and the physiological characteristic provides a direction for accurately checking whether the male and female cooped mice mate successfully.

At present, methods for identifying the success or failure of mouse cage mating mainly comprise a mouse vaginal smear method and a mouse vaginal suppository examination method. The mouse vaginal smear method has high accuracy, but the operation is complicated, and each caged female mouse needs to independently make a vaginal secretion smear, so that the time and the labor are wasted, and the speed of embolus detection is slow; the mouse vaginal suppository examination principle is direct and rapid, but a vaginal suppository with smaller volume or a vaginal suppository with deeper built-in is difficult to find by naked eyes. In addition, some black mice and brown mice have dark fur color and strong light absorption, so that under the illumination of a common fluorescent lamp in an SPF animal house, light reaching the vaginal opening of a female mouse is reduced, the difficulty is increased for the visual inspection of the vaginal suppository of the mouse, and the possibility of missed detection and wrong detection is improved.

Second, the mouse tail needs to be lifted during the procedure to examine the mouse vaginal suppository to expose the vaginal opening. However, the physiological characteristic of the tail lifting urination reflex of the mouse is that urine can block the vaginal orifice, form small liquid drops and pollute the vaginal orifice, which brings little trouble to the suppository detection work of a detector. Still other female mice have congenital defects such as vaginal mediastinum. The vaginal mediastinum is born at the mouse vaginal orifice and appears like a post-mating mouse embolus, which may confound the test results.

Accordingly, the present application provides a vaginal embolus detecting device and a detecting method, which can preferably improve the above-mentioned problems.

The engine cooling system and the vehicle of the present application will be described with reference to the drawings.

Fig. 1 is a schematic structural diagram of a vaginal embolus detecting device in an embodiment of the present application; FIG. 2 is a flow chart illustrating the detection of the vaginal embolus detecting device shown in FIG. 1; fig. 3 is a flow chart of the detection of the preferred embodiment of the vaginal embolus detection device shown in fig. 1. For the purpose of illustration, only the structures described in connection with the present application are illustrated in the drawings.

Referring to the drawings, the pessary detecting device 100 provided in at least one embodiment of the present application for detecting whether a pessary exists in a vagina of a laboratory animal includes an operating body 40, a light emitting member 10, a probe 20, and a light scattering member 30. The probe 20 has a first end and a second end which are oppositely arranged, the operation body 40 is connected with the first end of the probe 20, the light dispersion member 30 is connected with the second end of the probe 20, and the light emitting member 10 is arranged in the operation body 40.

In some embodiments, the operating body 40 is used to provide an operating space for an operator to hold. In some embodiments, the shape of the operation body 40 may be a cylindrical shape, a prism shape, or other shapes, and the present application is not limited thereto. As a preferred embodiment, the operating body 40 may be a cylindrical rod to improve the convenience of the operator.

Further, the operating body 11 may be a hollow cylindrical rod to effectively reduce the weight of the vaginal suppository detecting device 100 and improve the convenience of the vaginal suppository detecting device 100.

Further, the operation body 11 may be a hollow cylindrical rod, and the surface of the rod is further provided with concave and convex portions to improve the operability of the operator. In some embodiments, the concave-convex portion may be a texture machined on the surface of the operation body 11.

In some embodiments, the longitudinal length of the operating body 40 may be set to 40mm-60 mm.

In some embodiments, the operation body 40 has a light-focusing portion 41, and the light-focusing portion 41 is disposed at an end of the operation body 40 close to the probe 20. The radial dimension of the light-condensing portion 41 is configured to be gradually reduced from the operation body 40 toward the probe 20. Specifically, the light condensing portion 41 may be a tapered stage.

In some embodiments, the light emitting member 10 is disposed in the operation body 11 and can be used to generate light. In some embodiments, the light emitting member 10 is disposed in the light collecting portion 41 of the operation body 11. Thus, the light generated by the light emitting member 10 can be more concentrated, so as to improve the illumination effect of the light emitting member 10.

In some embodiments, the light emitting element can be an LED light source, so that the lighting effect is good and the energy consumption is low. It is understood that the illuminating element can be other illuminating light sources, and the application is not limited in this respect.

Further, the pessary detecting device 100 further includes an energy source disposed in the operating body 11 and connected to the light emitting member 10 for providing energy to the light emitting member 10. In some embodiments, the light emitting element 10 converts light energy from electrical energy, and the energy source element may be configured as a battery. It should be understood that the energy source may also provide energy to the glowing member 10 in other forms of energy.

In some embodiments, the vaginal suppository detection device 100 further includes a control member signally connected to the energy member to control whether the light-emitting member 10 emits light or not.

Further, the control member is also capable of controlling the intensity of the energy provided by the energy source member to the glowing member 10. Thus, the operator can conveniently adjust the luminous intensity of the luminous element 10 according to the experimental environment.

Further, the control member is coupled to the operating body 11. This can improve the convenience of the operator in controlling the luminous member 10.

In some embodiments, the operating body 11 has a first light-transmitting portion at an end close to the probe 20, and the light generated by the light-emitting element 10 can be transmitted to the first end of the probe 20 through the first light-transmitting portion.

In some embodiments, the first light-transmitting part may be a blind hole opened at an end of the operation body 11 close to the probe 20, and the blind hole opens toward the probe 20 and is connected to the first end of the probe 20. Further, the shape of the blind hole may be circular, prismatic, or triangular, and the present application is not limited specifically herein. As a preferred embodiment, the shape of the light emitting hole is selected to be circular, so that the light emitted from the light emitting member 10 can be condensed to improve the illumination effect.

In some embodiments, the first end of the probe 20 is removably attached to the handle body 11. Thus, when the probe 20 is damaged, the probe 20 can be conveniently detached and replaced.

In some embodiments, the first end of the probe 20 is provided with an external thread, and the inner wall of the operation body 11 is provided with an internal thread capable of being connected with the probe 20. In this way, the connection tightness between the probe 20 and the operation body 11 can be improved. In other embodiments, the first end of the probe 20 is also provided with an internal thread, and the outer wall of the operation body 11 is provided with an external thread capable of being matched and connected with the probe 20. In this way, the tightness of the connection between the probe 20 and the operation body 11 can be improved. In other embodiments, the probe 20 can be connected to the operation body 11 by clipping.

In some embodiments, the probe 20 has a second light-transmitting portion connected between the first end and the second end, and light transmitted to the first end can be transmitted to the second end through the second light-transmitting portion. In particular, in some embodiments, the probe 20 can be made of a transparent material, such as a transparent silicone material. In this manner, light can be conducted from the first end to the second end of the probe 20.

In some embodiments, the radial dimension of the probe 20 is configured to gradually decrease from the first end to the second end. Therefore, on one hand, the light emitted by the luminous piece 10 can be gathered, the light utilization rate is improved, the lighting effect is enhanced, and the detection efficiency and the detection precision of the vaginal suppository are improved; on the other hand, the probe 20 can be conveniently extended into the vagina of the experimental animal, so that the detection efficiency of the vaginal suppository is improved.

In particular, in some embodiments, the axial dimension of the probe 20 may be 20mm to 40 mm.

In some embodiments, the light diffuser 30 is disposed at the second end of the probe 20, and the light transmitted to the second end can be diffused inside the vagina of the experimental animal through the light diffuser 30 to improve visual brightness, so that a small volume of pessary inside the vagina or a pessary deep in the vagina can not be missed. Therefore, the detection efficiency and the detection precision of the vaginal suppository in the experimental animal vagina are improved.

In some embodiments, the light-scattering member 30 may be an ellipsoid, a sphere, or other body types. The utility model discloses the people is through practice and experiment repeatedly, finds the astigmatic piece 30 of oval size and gives a camera to the effect preferred that diverges. Therefore, as a preferred embodiment, the light dispersion member 30 is of an ellipsoidal type.

In some embodiments, the pessary detecting device 100 further comprises a cleaning member 60, and the cleaning member 60 is fixed at an end of the operation body 11 away from the probe 20 for cleaning the vaginal opening of the experimental animal.

In practical application, if contaminants, such as urine, exist at the vaginal orifice of the experimental animal, the detection accuracy of the vaginal suppository can be affected. The vaginal orifice of the test animal can be wiped by the cleaning member 60 to clean the contaminants, and then the probe 20 can be inserted into the vagina of the test animal. Therefore, the influence of pollutants at the vaginal orifice of the experimental animal on the detection precision of the pessary can be eliminated.

In particular, in some embodiments, the cleaning members 60 comprise at least one of cotton yarn and sponge. More specifically, the cleaning member 60 may be absorbent cotton, gauze, or other similar absorbent material.

In some embodiments, the vaginal suppository detecting device 100 further comprises a positioning member 70, the positioning member 70 is connected to an end of the operation body 11 far away from the probe 20, and the cleaning member 60 is fixed on the light emitting member 10 through the positioning member 70.

Further, the positioning member 70 is detachably attached to an end of the operation body 11 away from the probe 20. Particularly, in practical application, after the detection work of the cleaning piece 60 polluted by the bolt detection work on the same day is completed, the cleaning piece 60 can be replaced by detaching the positioning piece 70 for the detection work of the experimental animals in a batch.

Specifically, in some embodiments, the positioning member 70 is provided with an external thread, and the inner wall of the operation body 11 is provided with an internal thread capable of being connected with the positioning member 70 in a matching manner. In this way, the connection tightness between the retainer 70 and the operation body 11 can be improved. In other embodiments, the positioning member 70 is also provided with an internal thread, and the outer wall of the operation body 11 is provided with an external thread capable of being matched and connected with the positioning member 70. In this way, the tightness of the connection between the probe 20 and the operation body 11 can be improved. In other embodiments, the positioning member 70 may be connected to the operation body 11 by a snap-fit method.

In some embodiments, the positioning member 70 has a positioning cavity 71, and the opening of the positioning cavity 71 on the positioning member 70 is configured to form a positioning port 711. The cleaning member 60 is installed in the positioning cavity 71 and at least partially protrudes from the positioning hole 711. Thus, the stabilizing effect of the cleaning member 60 is improved, and the cleaning effect of the cleaning member 60 is not affected.

In some embodiments, the positioning port 711 is disposed at an end of the positioning member 70 away from the operating body 11. Thus, the cleaning convenience when using the pessary detecting device 100 is improved.

Further, the positioning hole 711 may have only one or a plurality of holes, and the present application is not limited in this respect.

An embodiment of the present application further provides a detection method of the vaginal suppository detection device 100, including the following steps:

step S310: the glowing member 10 is activated.

Step S320: the probe 20 is extended into the vagina of the experimental animal.

Step S330: the test animals were observed for the presence of vaginal emboli in their vagina.

In some embodiments, the step of observing the presence or absence of a vaginal plug in the vagina of the test animal further comprises the step of:

step S340: the probe 20 is flicked or slid within the vagina of the experimental animal to identify the vaginal plug.

Specifically, when a suppository examination work is performed on an experimental animal having mediastinum of vagina due to congenital defect, the mediastinum of vagina may be mistaken for a vaginal suppository. To avoid this, the accuracy of pessary detection can be improved by slightly flicking or sliding the probe 20 after the probe 20 enters the mouse vaginal opening. If a flesh-like tissue longitudinal span is observed at the mouse vaginal orifice and the probe 20 has a flesh-like tactile sensation, it is the vaginal mediastinum; if the probe 20 exhibits a hard waxy tactile feel, it is a vaginal plug.

The pessary detecting device 100 can clearly observe the pessary with smaller volume and the pessary positioned in the deep vagina by the divergent light of the light scattering member 30 positioned at the second end of the probe 20; the cleaning piece 60 can clean the pollutants at the vaginal orifice and eliminate the influence of the pollutants on the thrombus detection result; the diaphragm and pessary can be distinguished and differentiated by the tactile feel of the probe 20 inside the vagina. Therefore, the detection efficiency and the detection precision of the vaginal suppository of the experimental animal are improved.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only represent some embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

Claims (10)

1. A vaginal plug detection device, comprising:

operating the body;

the light-emitting piece is arranged in the operation body and used for generating light;

the probe is provided with a first end and a second end which are oppositely arranged, and the first end is matched and connected with one end of the operation body; and

a diffuser coupled to the second end;

the operating body is provided with a first light transmission part at one end close to the probe, and light generated by the light-emitting piece can be transmitted to the first end of the probe through the first light transmission part;

the probe is provided with a second light transmission part connected between the first end and the second end, light transmitted to the first end can be transmitted to the second end through the second light transmission part, and the light scattering part is used for scattering the light transmitted to the second end.

2. The vaginal plug detection device of claim 1, wherein the probe is configured to gradually decrease in radial dimension from the first end to the second end.

3. The pessary detection device of claim 1, wherein the diffuser is ellipsoidal.

4. The vaginal embolus detection device of claim 1, wherein the operation body is provided with a light-gathering part, and the light-gathering part is arranged at one end of the operation body close to the probe; the radial dimension of the light-condensing portion is configured to be gradually reduced from the operation body toward the probe.

5. The device of claim 4, wherein the light emitting member is disposed within the light focusing portion.

6. The device of claim 1, further comprising an energy source disposed within the operational body for providing a light-generating energy source to the light emitting member.

7. The device of claim 6, further comprising a control member coupled to the operating body and in signal communication with the energy source.

8. The device of claim 1, further comprising a cleaning member secured to an end of the operating body distal from the probe.

9. The device of claim 8, further comprising a positioning member detachably connected to an end of the operating body away from the probe, wherein the cleaning member is fixed to the operating body by the positioning member.

10. The vaginal embolus detection device of claim 9, wherein a positioning opening is formed in one side of the positioning member, the positioning member is provided with a positioning cavity communicated with the positioning opening, and the cleaning member is installed in the positioning cavity and at least partially protrudes out of the positioning opening.

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