CN214622331U - Saliva alpha amylase detection device - Google Patents
Saliva alpha amylase detection device Download PDFInfo
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- CN214622331U CN214622331U CN202120172897.1U CN202120172897U CN214622331U CN 214622331 U CN214622331 U CN 214622331U CN 202120172897 U CN202120172897 U CN 202120172897U CN 214622331 U CN214622331 U CN 214622331U
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Abstract
The utility model provides a saliva alpha amylase detection device, which comprises a sampling component and a detection component which are both in a flat plate shape, wherein the detection component and the sampling component are pivoted and fixed in a detachable mode; the saliva sampler comprises a sampling component, a detection component and a reaction component, wherein the sampling component is arranged on one side of the sampling component, which faces the detection component, and is used for collecting saliva to be detected, the detection component is arranged on one side of the detection component, which faces the water absorption component, the reaction component comprises a reaction part made of amylase reaction reagent, and when the detection component rotates to a preset position around a pin joint part, the reaction part is contacted with the water absorption component. The utility model discloses a set up the component that absorbs water and react the component, improved saliva detection efficiency greatly, and detect the saliva by the component collection that absorbs water, for the dry-type is collected, portable and operation, and easy operation is convenient, is favorable to popularizing and applying, can also effectively solve simultaneously and detect the problem that the saliva is lost and is mixed up, can use in the scene of utensil extensive detection quantity, has improved the practicality of using.
Description
Technical Field
The embodiment of the utility model provides a relate to medical instrument technical field, more specifically say, relate to a saliva alpha amylase detection device.
Background
Stress is defined as the state of homeostasis of an organism threatened by a potentially adverse physiological or psychological state (a state that is real or perceived.
Stress is inevitable. The body has evolved a response to stress aimed at maintaining healthy physiological functions, but frequent stress is detrimental to health. Stress leads to immune dysfunction, impaired cognitive ability and self-injury. Stress is associated with a number of diseases with a high incidence of aging, such as cardiovascular disease, atherosclerosis, cancer or type 2 diabetes. Aging is associated with several psychobiological changes, such as increased susceptibility to oxidative stress, imbalances in central neurotransmitter pathways, and changes in mood regulation.
Stress initiates a stress response by activating the hypothalamic-pituitary-adrenal axis, which leads to the release of glucocorticoids, and the sympatho-adrenal-medullary axis, which leads to the release of catecholamines-epinephrine and norepinephrine. The sympathetic-adrenal-medullary axis activation initially responds more rapidly upon stress activation than the hypothalamic-pituitary-adrenal axis.
Stress hormones are essential for quantifying and tracking stress responses. To better understand the stress response system, it is necessary to expand the scope of research on physiological stress markers. The development of a non-invasive method is very useful in assessing stress response.
The saliva test is a nondestructive diagnostic tool for the testee and can help to prevent, diagnose and treat various diseases. Advantages and advantages of saliva analysis:
the saliva is used as a detection sample, and has the advantages of convenient collection, repeated collection, no restriction of environment and time and easy operation.
And saliva inspection can reduce the damage of the organism, and has the characteristics of no wound, no stimulation and pain.
And thirdly, saliva inspection can reduce detection conditions and detection cost, improve detection speed and dynamically monitor indexes.
And fourthly, the risk of infecting hepatitis B virus, HIV virus and the like in the inspection process is reduced.
At present, the existing saliva detection method mostly uses a sampling tube to collect saliva, and then sends the sampling tube to a detection center for detection. The existing saliva detection method is a non-dry detection method, and a detection result cannot be directly obtained on site, so that the detection efficiency is low, the saliva detection method is inconvenient to operate and carry, and the popularization and the application of the saliva detection are not facilitated.
In addition, the existing saliva detection method collects saliva by means of a sampling tube and cannot directly detect the saliva, so that the problems of loss and confusion exist, and the practicability is insufficient.
SUMMERY OF THE UTILITY MODEL
The embodiment of the utility model provides a to above-mentioned unable on-the-spot direct acquisition testing result of present saliva detection method, detection efficiency low, be not convenient for operation and carry, be unfavorable for the popularization and application of saliva detection and the problem that the existence is lost and is mixed up, provide a saliva alpha amylase detection device.
The embodiment of the present invention provides a saliva alpha amylase detecting device, which comprises a sampling member and a detecting member, both of which are flat-shaped, wherein the detecting member and the sampling member are pivotally connected and fixed in a detachable manner; the saliva detection device comprises a sampling component, a detection component and a reaction component, wherein the sampling component is provided with a water absorption component for collecting saliva to be detected on one side facing the detection component, the detection component is provided with a reaction component on one side facing the water absorption component, the reaction component comprises a reaction part made of amylase reaction reagent, and when the detection component rotates to a preset position around a pin joint part, the reaction part is in contact with the water absorption component.
Preferably, the detection member includes a first detection window, the reaction member includes a main body portion made of a transparent material, and the reaction portion is located on a side of the main body portion facing the sampling member; the reaction member covers the first detection window, and the first detection window is opposite to the reaction part, and the reaction part is optically detected through the first detection window.
Preferably, the sampling member includes a second detection window, the water absorbing member covers the second detection window, and when the reaction portion is in contact with the water absorbing member, the second detection window is opposed to the reaction portion, and optically detects the reaction portion through the first detection window and the second detection window.
Preferably, the saliva alpha amylase detection device further comprises a protection member in a flat plate shape, and the protection member is positioned on one side of the sampling member, which is opposite to the detection member, and is symmetrically distributed with the detection member;
the protective component comprises a third detection window and is pivoted and fixed with the sampling component in a detachable mode; when the protection member and the detection member are respectively buckled on the sampling member, the water absorption member on the sampling member is positioned between the protection member and the detection member, and the third detection window is opposite to the second detection window.
Preferably, a first elastic buckle in a C shape is arranged in the middle of the sampling member, the first elastic buckle is arranged along the width direction of the sampling member, the sampling member is divided by the first elastic buckle to form a handle section and a sampling section, and the water absorbing member is arranged in the sampling section;
one end of the detection component is provided with a first pivot shaft matched with the first elastic buckle, the first pivot shaft is perpendicular to the length direction of the detection component, and the detection component is pivoted and fixed with the sampling component in a mode that the first pivot shaft is clamped into the first elastic buckle;
a C-shaped second elastic buckle is arranged on one side, back to the first elastic buckle, of the sampling component, and the opening direction of the second elastic buckle is opposite to that of the first elastic buckle; one end of the protection component is provided with a second pivot shaft matched with the second elastic buckle, the second pivot shaft is perpendicular to the length direction of the protection component, and the protection component is pivoted and fixed with the sampling component in a mode that the second pivot shaft is clamped into the second elastic buckle.
Preferably, the reaction member comprises a hydrophobic part, the hydrophobic part is positioned on one side of the main body part facing the sampling member, and the reaction part is made of amylase reaction reagent through a vacuum drying process;
the hydrophobic part surrounds the periphery of the reaction part, and is formed by molding a waterproof material to the surface of the main body part by a laser printing technology.
Preferably, the outer edge of one side, facing the sampling member, of the detection member is provided with a first clamping edge structure, the outer edge of the sampling member is provided with a first clamping groove structure matched with the first clamping edge structure, and when the detection member is fastened to the sampling member, the first clamping edge structure is clamped into the first clamping groove structure in a tight fit manner so as to limit and fix the detection member on the sampling member;
the outer edge of one side, facing the sampling component, of the protection component is provided with a second clamping edge structure, the outer edge of the sampling component is provided with a second clamping groove structure matched with the second clamping edge structure, and when the protection component is buckled on the sampling component, the second clamping edge structure is clamped in the second clamping groove structure in a tight fit mode so as to limit and fix the protection component on the sampling component;
when the protection component and the detection component are respectively buckled on the sampling component, the sampling section of the sampling component is positioned in a cavity formed by the protection component and the detection component.
Preferably, theThe thickness of the water absorbing component is 0.2-0.5 mm, and the water absorption capacity of the water absorbing component is 5-20ul/cm2The water absorbing member is adhered and fixed on the sampling member through an adhesive layer; the water absorbing member is made of glass cellulose, quantitative filter paper, or cellulose acetate.
Preferably, the reaction member is in a rectangular sheet shape, and the thickness of the reaction member is 0.1-0.5 mm; the main body part of the reaction member is made of polyethylene terephthalate, polymethyl methacrylate, polystyrene or polycarbonate;
one side of the detection component, which faces the sampling component, is provided with an assembly groove matched with the reaction component, and the reaction component is adhered and fixed in the assembly groove through an adhesive layer; when the reaction member is fitted into the fitting groove, the reaction portion of the reaction member protrudes from the opening plane of the fitting groove.
Preferably, the first detection window, the second detection window and the third detection window are respectively formed by a plurality of through holes arranged along the length direction of the saliva alpha amylase detection device.
The utility model discloses saliva alpha amylase detection device has following beneficial effect: by arranging the water absorbing member on the sampling member and the reaction member on the detection member, the reaction part of the reaction member is contacted with the water absorbing member when the detection member rotates to a preset position around the rotating part, that is, the saliva to be detected is collected by the water absorption component, the reaction part of the reaction component is contacted with the saliva to be detected to carry out chemical reaction, the content of amylase in the saliva to be detected is reflected by the color generated by the reaction part, at this time, the color of the reaction part of the reaction component is observed only by external detection equipment, the content data of amylase in the saliva to be detected can be obtained, the saliva detection is completed, so that the detection result can be directly obtained on site after the saliva is collected, the saliva detection efficiency is greatly improved, the saliva to be detected is collected by the water absorption component, and the dry collection is convenient to carry and operate, is simple and convenient to operate and is beneficial to popularization and application; because above-mentioned detection device detects saliva through the collection of the component that absorbs water, and can on-the-spot direct detection, consequently effectively solved and detected the problem that saliva lost and mix up, and then can use in the on-the-spot of utensil extensive detection quantity, improved the practicality of using.
Drawings
Fig. 1 is a schematic structural diagram of a saliva alpha amylase detection device provided by an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a lateral projection of a saliva alpha amylase detection device provided by an embodiment of the present invention;
FIG. 3 is a schematic structural diagram of a reaction member provided in an embodiment of the present invention;
fig. 4 is a schematic structural diagram of a vertical projection of a saliva alpha amylase detection device provided by an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
As shown in fig. 1, the structural schematic diagram of the saliva alpha amylase detection device provided by the embodiment of the present invention is shown, and the saliva alpha amylase detection device can be applied to the technical field of medical devices. Referring to fig. 2, the saliva α -amylase detecting device in this embodiment includes a sampling member 1 and a detecting member 2, both of which are in a flat plate shape, and the detecting member 2 and the sampling member 1 are pivotally connected and fixed in a detachable manner, so that the detecting member 2 can rotate relative to the sampling member 1, thereby avoiding obstructing the sampling operation of the sampling member 1. In practical applications, the sampling member 1 and the detecting member 2 are preferably in the form of long flat plates, which facilitates the sampling and storing operations.
The pivoting structure between the detection member 2 and the sampling member 1 can be determined according to actual conditions; for example, the detection member 2 is assembled with the sampling member 1 in a clamping manner, and the clamping manner is convenient for simplifying the structural design and is beneficial to realizing detachable fixed connection. The detection member 2 and the sampling member 1 are detachably connected, which is beneficial to the processing and assembly of the detection member 2 and the sampling member 1.
Specifically, the side of the sampling member 1 facing the detection member 2 is provided with a water absorbing member 3 (such as a water absorbing paper) for collecting saliva to be detected, and the water absorbing member 3 is preferably arranged at a position close to the end of the sampling member 1, so that the water absorbing member 3 can be placed under the tongue when the sampling member 1 extends into the oral cavity, thereby completing the collection of saliva.
Referring to fig. 3, the side of the detecting member 2 facing the water absorbing member 3 is provided with a reaction member 4, the reaction member 4 includes a reaction part 41 made of an amylase reaction reagent (i.e., a detection reagent for amylase detection), the size of the reaction part 41 can be determined according to actual conditions, and the reaction part 41 is in contact with the water absorbing member 3 when the detecting member 2 rotates around the pivot part to a preset position. Because the reaction part 41 is made of amylase reaction reagent and the saliva to be detected in the water absorbing component 3 contains amylase, the reaction part 41 can generate chemical reaction under the catalysis of the amylase so as to generate color, and at the moment, the activity and the content of the saliva amylase in the saliva to be detected can be obtained only by obtaining the color depth of the reaction part 41, so that the function of detecting the saliva is achieved.
The preset position can be determined according to actual conditions, and is preferably the position where the detection component 2 is buckled on the sampling component 1, so that the convenience of operation is improved. The pivoting portion is a structure in which the detecting member 2 is pivotally connected to the sampling member 1.
The using steps are as follows: opening and rotating the detection member 2, keeping the detection member 2 away from the water absorbing member 3, placing the part of the sampling member 1 provided with the water absorbing member 3 below the tongue (the specific position can be adjusted according to the actual situation), collecting enough saliva to be detected by the water absorbing member 3, taking out the sampling member 1, then folding the detection member 2, enabling the reaction member 4 to be in contact with the water absorbing member 3, standing for a certain time, carrying out optical detection (light reflection detection and light perspective detection) on the reaction part 41 of the reaction member 4 through external detection equipment (such as a biological test paper detection device), obtaining the color depth of the reaction part 41, and finally obtaining the amylase content in the saliva to be detected through an algorithm. Of course, the saliva alpha-amylase detecting device of the embodiment can also be applied to saliva detection of other saliva biomarkers (such as dogs), and is not limited to saliva detection of human bodies.
Above-mentioned saliva alpha amylase detection device is through setting up water absorbing member 3 at sampling component 1, set up reaction member 4 at detection component 2, so when detection component 2 rotates to predetermineeing the position around the rotating part, reaction unit 41 of reaction member 4 contacts with water absorbing member 3, it treats saliva by water absorbing member 3 collection promptly, reaction unit 41 by reaction member 4 contacts with treating saliva, in order to carry out chemical reaction, and produce the color through reaction unit 41 and reflect the content of amylase in treating saliva, only need at this moment to observe the color of reaction unit 41 of reaction member 4 through external testing equipment, can acquire the content data of amylase in treating saliva, accomplish saliva detection, thereby can directly obtain the testing result on the spot after having collected saliva, saliva detection efficiency has been improved greatly.
In addition, above-mentioned saliva alpha amylase detection device is collected by water absorption component 3 and is waited to detect saliva, for dry-type collection, portable and operation, and easy operation is convenient, is favorable to popularizing and applying. In addition, the saliva to be detected is collected by the saliva alpha amylase detection device through the water absorption component 3, and the saliva to be detected can be directly detected on site, so that the problems of loss and confusion of the saliva to be detected are effectively solved, the saliva alpha amylase detection device can be used on site with large-scale detection quantity, and the practicability of use is improved.
In an embodiment of the present invention, the detecting member 2 includes a first detecting window 21, the reaction member 4 includes a main body portion made of a transparent material (preferably polyethylene terephthalate), and the reaction portion 41 is located on one side of the main body portion facing the sampling member 1, so as to ensure that the reaction portion 41 can reliably contact with the water absorbing member 3, and avoid contact failure due to misalignment. Further, the reaction member 4 covers the first detection window 21 of the detection member 2, and the first detection window 21 is opposite to the reaction portion 41 of the reaction member 4, but since the main body portion of the reaction member 4 is transparent, the reaction portion 41 can be optically detected through the first detection window 21, that is, the reaction portion 41 of the reaction member 4 can be optically detected through the first detection window 21 by an external detection device to obtain the shade of the reaction portion 41.
In practical applications, the first detection window 21 may be specifically set according to a light source of an external detection device; for example, it is composed of a plurality of through holes arranged along a straight line to correspond to a plurality of light sources on the external detection device to realize the optical detection of reflection and/or transmission.
In order to facilitate the optical perspective detection of the reaction part 41 of the reaction member 4, the above-mentioned sampling member 1 is provided with the second detection window 11, and the water absorbing member 3 covers the second detection window 11, and when the reaction part 41 is in contact with the water absorbing member 3, the second detection window 11 is opposed to the reaction part 41, whereby the reaction part 41 can be optically detected by reflection and/or transmission through the first detection window 21 and the second detection window 11. Of course, the detection mode of the reaction portion 41 can be specifically determined according to actual conditions. When the detecting member 2 rotates to the predetermined position around the pivot portion, the first detecting window 21 and the second detecting window 11 are preferably located on the same straight line.
The structural design of the second detection window 11 may be the same as that of the first detection window 21; for example, the structure is convenient to unify due to the fact that the through holes are formed by the through holes which are arranged along a straight line, the structural design can be simplified, and the compatibility with the same external detection equipment can be guaranteed.
In the utility model discloses a in another implementation, saliva alpha amylase detection device is still including being flat-plate-shaped protective member 5, and protective member 5 is located sampling member 1 one side that detects component 2 dorsad to with detect component 2 symmetric distribution, protective member 5 is located the one side that absorbs water component 3 detected component 2 dorsad promptly, can be enclosed by protective member 5 and detection component 2 like this and close the parcel and absorb water component 3, improve the reliability of detection.
The protection member 5 includes a third detection window 51, and the protection member 5 is detachably pivotally connected to the sampling member 1. When the protection member 5 and the detection member 2 are respectively buckled on the sampling member 1, the water absorption member 3 on the sampling member 1 is positioned between the protection member 5 and the detection member 2, and the third detection window 51 is opposite to the second detection window 11, so that the existence of the protection member 5 is prevented from blocking the optical perspective detection of an external detection device. In particular, the first detection window 21, the second detection window 11 and the third detection window 51 are preferably located on the same line when the detection member 2 and the guard member 5 are rotationally snapped onto the sampling member 1. The third detection window 51 may have the same structural design as the first detection window 21; for example, it is constituted by a plurality of through holes arranged in a straight line.
In practical applications, the sampling member 1, the shielding member 5 and the detecting member 2 are preferably made of black opaque materials (e.g., plastics), which facilitates the external detecting device to optically detect the reaction portion 41 through the first detecting window 21, the second detecting window 11 and the third detecting window 51.
In an embodiment of the present invention, the middle of the sampling member 1 is provided with a first elastic buckle 12 in a C shape, the first elastic buckle 12 is disposed along the width direction of the sampling member 1, the sampling member 1 is separated by the first elastic buckle 12 to form a handle section 13 and a sampling section 14, and the water absorbing member 3 is disposed in the sampling section 14. The sampling component 1 is convenient to carry and handle by forming the handle section 13, and the stability in the operation process is improved. Of course, an anti-slip structure (such as a pattern) may be disposed on the handle segment 13, or the shape of the handle segment 13 may be adapted to the palm, so as to improve the stability of holding the hand, so that the saliva alpha amylase detection device is not easy to fall off, and waste is avoided. The first elastic buckle 12 is preferably made of plastic or plastic material, and has small processing difficulty and low material cost, thereby being beneficial to batch manufacturing and controlling the manufacturing cost. Of course, the first elastic buckle 12 can be made of other materials, such as stainless steel, according to the actual situation.
Furthermore, one end of the detecting member 2 is provided with a first pivot shaft 22 adapted to the first elastic buckle 12, the first pivot shaft 22 is perpendicular to the length direction of the detecting member 2, and the detecting member 2 is pivotally connected to the sampling member 1 by the way that the first pivot shaft 22 is clamped into the first elastic buckle 12. Because first elasticity buckle 12 is the C style of calligraphy, consequently, can guarantee that first elasticity buckle 12 possesses better elasticity, be favorable to first pin joint axle 22 card to go into first elasticity buckle 12 in, when the installation promptly, accessible extrusion makes first elasticity buckle 12 take place elastic deformation, and then the card is gone into in the buckle position of first elasticity buckle 12, can enough realize dismantling between detection component 2 and the sampling component 1 and be connected from this, can guarantee again that the pin joint of detection component 2 and sampling component 1 is fixed, make detection component 2 can be around pin joint portion (being first pin joint axle 22) do the rotary motion for sampling component 1.
Because the first elastic buckle 12 is arranged along the width direction of the sampling member 1, and the first pivot shaft 22 is perpendicular to the length direction of the detection member 2 (i.e. the width direction of the detection member 2), the detection member 2 is pivotally connected and fixed with the sampling member 1 in a manner that the first pivot shaft 22 is matched with the first elastic buckle 12, so that the detection member 2 can be prevented from rotating around the first pivot shaft 22 and protruding towards the width direction of the sampling member 1, the rationality of the structural design is improved, and meanwhile, the detection member 2 is prevented from rotating towards the width direction of the sampling member 1 and hindering the sampling operation of the sampling member 1 (i.e. the collection operation of saliva to be detected) or causing scratches or scratches.
Similarly, a second elastic buckle 15 having a C-shape is disposed on a side of the sampling member 1 facing away from the first elastic buckle 12, and an opening direction of the second elastic buckle 15 is opposite to an opening direction of the first elastic buckle 12. One end of the protection component 5 is provided with a second pivot shaft 52 matched with the second elastic buckle 15, the second pivot shaft 52 is perpendicular to the length direction of the protection component 5, and the protection component 5 is pivotally connected and fixed with the sampling component 1 in a mode that the second pivot shaft 52 is clamped into the second elastic buckle 15. The above-mentioned pivot connection between the protection member 5 and the sampling member 1 can be the same as the pivot connection between the detection member 2 and the sampling member 1, and will not be described herein again.
In another embodiment of the present invention, the reaction member 4 comprises a hydrophobic portion 42, the hydrophobic portion 42 is located on one side of the main body portion facing the sampling member 1, and the reaction portion 41 of the reaction member 4 is made of an amylase reaction reagent by a vacuum drying process. And, the hydrophobic part 42 is surrounded on the outer circumference of the reaction part 41, and the hydrophobic part 42 is formed of a water-repellent material (preferably a water-repellent ink) molded to the surface of the body part by a laser printing technique to form a hydrophobic barrier, serving a hydrophobic function. Because the hydrophobic part 42 surrounds the periphery of the reaction part 41, the saliva to be detected on the water absorbing member 3 can be more easily contacted with the reaction part 41, the reaction of the reaction part 41 and amylase in the saliva to be detected is ensured to be more thorough, and the detection is more accurate.
In addition, the outer edge of one side of the detection member 2 facing the sampling member 1 is provided with a first clamping edge structure 23, the outer edge of the sampling member 1 is provided with a first clamping groove structure 16 matched with the first clamping edge structure 23, and when the detection member 2 is buckled on the sampling member 1, the first clamping edge structure 23 is clamped in the first clamping groove structure 16 in a tight fit manner so as to limit and fix the detection member 2 on the sampling member 1. The mode joint that detects the component 2 through the tight fit is to sample component 1, conveniently dismantles and detects component 2 and will detect component 2 and lock to sample component 1 on, improves convenient operation nature, can simplify the structure simultaneously, avoids making the structure complicated and improve manufacturing cost.
Similarly, the outer edge of the side of the protection member 5 facing the sampling member 1 is provided with a second clamping edge structure 53, the outer edge of the sampling member 1 is provided with a second clamping groove structure 17 matched with the second clamping edge structure 53, and when the protection member 5 is fastened on the sampling member 1, the second clamping edge structure 53 is clamped in the second clamping groove structure 17 in a tight fit manner, so as to limit and fix the protection member 5 on the sampling member 1.
In practical application, the connection between the detecting member 2 and the sampling member 1 and the connection between the protecting member 5 and the sampling member 1 can be determined according to practical situations; for example, the detection component 2 and the protection component 5 are provided with a clamping groove structure, the sampling component 1 is provided with a clamping edge structure, and the detection component 2 and the protection component 5 are locked on the sampling component 1 in a manner of being tightly matched and connected with the clamping edge structure through the clamping groove structure.
In particular, when the protection member 5 and the detection member 2 are respectively buckled on the sampling member 1, the sampling section 14 of the sampling member 1 is positioned in a cavity formed by the protection member 5 and the detection member 2, so that the water absorbing member 3 is positioned in the cavity, the water absorbing member 3 can be protected, meanwhile, the water absorbing member 3 is prevented from contacting with the outside air to absorb moisture in the air, the concentration of saliva to be detected is prevented from being influenced, and the detection accuracy is ensured.
In one embodiment of the present invention, the thickness of the water absorbing member 3 is 0.2-0.5 mm (the thickness of the water absorbing member 3 is preferably 0.3mm), and the water absorption capacity of the water absorbing member 3 is 5-20ul/cm2(the water absorption capacity of the water-absorbent member 3 is preferably 15ul/cm2) And the water absorbing member 3 may be fixed to the sampling member 1 by adhesion with an adhesive layer (e.g., double-sided tape). The water absorbing member 3 may be water absorbing paper, and the material is preferably glass cellulose. Of course, in practical applications, the material of the water absorbing member 3 may be quantitative filter paper or cellulose acetate, and may be determined according to practical situations.
In another embodiment of the present invention, the reaction member 4 is a rectangular sheet, and the thickness of the reaction member 4 is 0.1-0.5 mm (the thickness of the reaction member 4 is preferably 0.2 mm). In particular, the main body of the reaction member 4 may also be composed of polymethyl methacrylate, polystyrene or polycarbonate.
Furthermore, the side of the detection member 2 facing the sampling member 1 is provided with a fitting groove 24, and the reaction member 4 is fixed in the fitting groove 24 by adhesive layer bonding (e.g. applying glue). The shape and size of the assembly groove 24 are preferably matched with those of the reaction component 4, so that the reaction component 4 can be limited by the assembly groove 24, the installation difficulty of the reaction component 4 can be reduced, the reaction component 4 can be positioned by the assembly groove 24, the position precision of the reaction component 4 is improved, and the play dislocation is avoided.
To ensure that the reaction part 41 of the reaction member 4 can be reliably brought into contact with the water absorbing member 3, the reaction part 41 of the reaction member 4 should protrude out of the plane of the opening of the fitting groove 24 when the reaction member 4 is fitted into the fitting groove 24.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention should be covered by the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (10)
1. The saliva alpha amylase detection device is characterized by comprising a sampling component and a detection component which are both in a flat plate shape, wherein the detection component and the sampling component are pivoted and fixed in a detachable mode; the saliva detection device comprises a sampling component, a detection component and a reaction component, wherein the sampling component is provided with a water absorption component for collecting saliva to be detected on one side facing the detection component, the detection component is provided with a reaction component on one side facing the water absorption component, the reaction component comprises a reaction part made of amylase reaction reagent, and when the detection component rotates to a preset position around a pin joint part, the reaction part is in contact with the water absorption component.
2. The salivary alpha amylase testing device of claim 1, wherein the testing member comprises a first testing window, the reaction member comprises a main body portion composed of a transparent material, and the reaction portion is located on a side of the main body portion facing the sampling member; the reaction member covers the first detection window, and the first detection window is opposite to the reaction part, and the reaction part is optically detected through the first detection window.
3. The salivary alpha amylase testing device according to claim 2, wherein the sampling member comprises a second testing window, the water absorbing member covers the second testing window, and when the reaction part is in contact with the water absorbing member, the second testing window is opposite to the reaction part, and the reaction part is optically tested through the first and second testing windows.
4. The saliva alpha-amylase testing device of claim 3, further comprising a guard member having a flat plate shape, wherein the guard member is located on a side of the sampling member opposite to the testing member and is symmetrically distributed with the testing member;
the protective component comprises a third detection window and is pivoted and fixed with the sampling component in a detachable mode; when the protection member and the detection member are respectively buckled on the sampling member, the water absorption member on the sampling member is positioned between the protection member and the detection member, and the third detection window is opposite to the second detection window.
5. The saliva alpha-amylase detecting device according to claim 4, wherein a first elastic buckle in a C shape is arranged in the middle of the sampling member, the first elastic buckle is arranged along the width direction of the sampling member, the sampling member is divided by the first elastic buckle to form a handle section and a sampling section, and the water absorbing member is arranged in the sampling section;
one end of the detection component is provided with a first pivot shaft matched with the first elastic buckle, the first pivot shaft is perpendicular to the length direction of the detection component, and the detection component is pivoted and fixed with the sampling component in a mode that the first pivot shaft is clamped into the first elastic buckle;
a C-shaped second elastic buckle is arranged on one side, back to the first elastic buckle, of the sampling component, and the opening direction of the second elastic buckle is opposite to that of the first elastic buckle; one end of the protection component is provided with a second pivot shaft matched with the second elastic buckle, the second pivot shaft is perpendicular to the length direction of the protection component, and the protection component is pivoted and fixed with the sampling component in a mode that the second pivot shaft is clamped into the second elastic buckle.
6. The salivary alpha amylase testing device of claim 2, wherein the reaction member comprises a hydrophobic part, the hydrophobic part is positioned on one side of the main body part facing the sampling member, and the reaction part is made of amylase reaction reagent through a vacuum drying process;
the hydrophobic part surrounds the periphery of the reaction part, and is formed by molding a waterproof material to the surface of the main body part by a laser printing technology.
7. The saliva alpha-amylase detecting device according to claim 5, wherein an outer edge of a side of the detecting member facing the sampling member is provided with a first clamping edge structure, an outer edge of the sampling member is provided with a first clamping groove structure matched with the first clamping edge structure, and when the detecting member is buckled on the sampling member, the first clamping edge structure is clamped in the first clamping groove structure in a tight fit manner so as to position and fix the detecting member on the sampling member;
the outer edge of one side, facing the sampling component, of the protection component is provided with a second clamping edge structure, the outer edge of the sampling component is provided with a second clamping groove structure matched with the second clamping edge structure, and when the protection component is buckled on the sampling component, the second clamping edge structure is clamped in the second clamping groove structure in a tight fit mode so as to limit and fix the protection component on the sampling component;
when the protection component and the detection component are respectively buckled on the sampling component, the sampling section of the sampling component is positioned in a cavity formed by the protection component and the detection component.
8. The saliva alpha-amylase detecting device of claim 1, wherein the thickness of the water absorbing member is 0.2-0.5 mm, and the water absorption capacity of the water absorbing member is 5-20ul/cm2The water absorbing member is adhered and fixed on the sampling member through an adhesive layer; the water absorbing member is made of glass cellulose, quantitative filter paper, or cellulose acetate.
9. The salivary alpha amylase testing device according to claim 1, wherein the reaction member is in a rectangular sheet shape, and the thickness of the reaction member is 0.1-0.5 mm; the main body part of the reaction member is made of polyethylene terephthalate, polymethyl methacrylate, polystyrene or polycarbonate;
one side of the detection component, which faces the sampling component, is provided with an assembly groove matched with the reaction component, and the reaction component is adhered and fixed in the assembly groove through an adhesive layer; when the reaction member is fitted into the fitting groove, the reaction portion of the reaction member protrudes from the opening plane of the fitting groove.
10. The saliva alpha-amylase detecting device according to claim 6, wherein the first detecting window, the second detecting window, and the third detecting window are respectively formed by a plurality of through holes arranged along a length direction of the saliva alpha-amylase detecting device.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120172897.1U CN214622331U (en) | 2021-01-21 | 2021-01-21 | Saliva alpha amylase detection device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120172897.1U CN214622331U (en) | 2021-01-21 | 2021-01-21 | Saliva alpha amylase detection device |
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| CN214622331U true CN214622331U (en) | 2021-11-05 |
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| CN202120172897.1U Active CN214622331U (en) | 2021-01-21 | 2021-01-21 | Saliva alpha amylase detection device |
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