CN214621846U - Dry blood spot and dry urine spot collecting card - Google Patents
Dry blood spot and dry urine spot collecting card Download PDFInfo
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- CN214621846U CN214621846U CN202120875327.9U CN202120875327U CN214621846U CN 214621846 U CN214621846 U CN 214621846U CN 202120875327 U CN202120875327 U CN 202120875327U CN 214621846 U CN214621846 U CN 214621846U
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Abstract
The utility model relates to a dry blood spot and dry urine spot collection card, the collection card includes along horizontal protective layer, sample acquisition district and the information acquisition district that connects gradually. The protective layer is foldable along a line of attachment between the protective layer and the sample acquisition region to cover the sample acquisition region. The sample collection area includes two separate sample retention areas. The utility model discloses a dry blood spot and dry urine spot in the sample acquisition district can effectively be protected to the protective layer that the acquisition card set up, and the protection has the trace substance molecule that detects the meaning, improves qualitative and quantitative analysis's the result degree of accuracy. The acquisition card is convenient to use, free of environmental pollution and low in cost, and can be used for collecting and storing urine and blood samples so as to detect trace substances in dry urine spots and dry blood spots.
Description
Technical Field
The utility model relates to a medical sampling equipment field, concretely relates to dry blood spot and dry urine spot collection card is applicable to and carries out gas chromatography, liquid chromatography, gas chromatography/mass spectrum and liquid chromatography/mass spectrum analysis to trace substance in dry blood spot and the dry urine spot, needs to carry out the condition of gathering and preserving to blood sample, urine sample.
Background
The technology for collecting dry blood spots and dry urine spots is a novel blood collection and urine collection and storage mode, namely, a small amount of blood or urine is dripped on a filter paper card, and the filter paper card is placed at normal room temperature and dried to complete the preparation of the dry blood spots and the dry urine spots. The clinical dry blood spot and dry urine spot technology meets the requirements of convenient sampling, small injury, low sample volume and convenient transportation and storage, and is also convenient for clinical monitoring and rapid detection. The dry blood spot and dry urine spot technology is applied to aspects of clinical disease marker screening, pharmacokinetic research, clinical drug monitoring and the like. However, the existing filter paper for preserving the dry blood spots and the dry urine spots has no protective measures, has weak protection on the dry blood spots and the dry urine spots, is easy to lose trace substance molecules with detection significance, and leads to inaccurate results of qualitative and quantitative analysis.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an easy and simple to handle for preserve the collection card of dry blood spot and dry urine spot, use filter paper to preserve dry blood spot and dry urine spot that exist at present in order to solve, nevertheless have the trace substance molecule distribution that detects the meaning between filter paper cellulose chain, make to have the unsafe problem of qualitative and quantitative analysis result of the trace substance molecule that detects the meaning. The utility model adopts the following technical proposal to realize the purpose.
The utility model provides a dry blood spot and dry urine spot collecting card, the collecting card includes along horizontal protective layer, sample acquisition district and the information acquisition district that connects gradually. The protective layer is foldable along a line of attachment between the protective layer and the sample acquisition region to cover the sample acquisition region. The sample collection area includes two separate sample retention areas.
As the further improvement of the dry blood spot and dry urine spot collecting card of the utility model, every the sample preservation area is circular.
As a further improvement of the dry blood spot and dry urine spot collecting card of the utility model, each sample storage area is provided with a piece of filter paper containing anticoagulant; each of the filter papers is a circle of the same size as the sample holding area.
As a further improvement of the collection card for the dry blood spots and the dry urine spots, the anticoagulant is ethylene diamine tetraacetic acid dipotassium.
As a further improvement of the dry blood spot and dry urine spot collecting card of the utility model, every filter paper is medium-speed quantitative filter paper.
As the utility model discloses a dry blood spot and dry urine spot collection card's further improvement, two filter paper is in along vertically (above-mentioned protective layer is horizontal to the direction of sample acquisition district to collection information district) laying in the sample acquisition district.
As the utility model discloses a dry blood spot and dry urine spot collection card's further improvement, protective layer, sample acquisition district and collection information district are squarely, the protective layer with the overall dimension in sample acquisition district is the same.
As a further improvement of the dry blood spot and dry urine spot collecting card of the utility model, the total length of the collecting card is 18cm, and the width is 5 cm; wherein the protective layer and the sample acquisition area are both 4.5cm in length, and the information acquisition area is 9cm in length; the width of the protective layer, the width of the sample collecting area and the width of the information collecting area are all 5 cm.
As the utility model discloses a dry blood spot and dry urine spot collection card's further improvement, the protective layer is transparent or translucent, the printing has the typeface on the protective layer, and this typeface printing is in the one side that deviates from the sample collection district.
As a further improvement of the dry blood spot and dry urine spot collecting card of the utility model, the collecting information area is printed with the characters of name, gender, nationality, identity card number, household registration and current address.
The utility model has the advantages that: the utility model discloses a dry blood spot and dry urine spot in the sample acquisition district can effectively be protected to the protective layer that the acquisition card set up, and the protection has the trace substance molecule that detects the meaning, improves qualitative and quantitative analysis's the result degree of accuracy. The acquisition card is convenient to use, free of environmental pollution and low in cost, and can be used for collecting and storing urine and blood samples so as to detect trace substances in dry urine spots and dry blood spots.
Drawings
Fig. 1 is a schematic diagram of the overall structure of a dry blood spot and dry urine spot collecting card according to an embodiment of the present invention.
Fig. 2 is a schematic diagram of the dry blood spot and dry urine spot collecting card after separating each region according to the embodiment of the present invention.
Reference numerals: a protective layer 1, a sample collection area 2, an information collection area 3, and a sample storage area 20.
Detailed Description
To make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the drawings of the embodiments of the present invention are combined to clearly and completely describe the technical solutions of the embodiments of the present invention, and obviously, the described embodiments are some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention. Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work all belong to the protection scope of the present invention.
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings.
As shown in attached figures 1 and 2, the structure of the collection card for dry blood spots and dry urine spots of the present invention is schematically illustrated. The acquisition card comprises a protective layer 1, a sample acquisition area 2 and an information acquisition area 3 which are sequentially connected along the transverse direction. The protective layer 1 is foldable along a connection line between the protective layer 1 and the sample collection area 2 to cover the sample collection area 2. The sample collection area 2 comprises two separate sample retention areas 20, covered and protected by a protective layer 1. The sample may be a blood or urine sample.
Each of the sample retention areas 20 is circular. Each sample storage area 20 is provided with a piece of filter paper soaked with anticoagulant; each of the filter papers is a circle having the same size as the sample retention area 20. Each piece of filter paper is medium-speed quantitative filter paper. The two pieces of filter paper are arranged in the sample collection area 2 along the longitudinal direction, namely the up-down direction of the sample collection area 2.
Wherein the anticoagulant is ethylene diamine tetraacetic acid dipotassium salt. The anticoagulant can slow down the coagulation of blood and urine samples, so that dry blood spots and dry urine spots on the collection card are kept in a wet state, and the extraction and detection of effective components in the blood and urine samples are facilitated.
Due to the characteristics of the filter paper substrate, trace substance molecules with detection significance are distributed among filter paper cellulose chains, dry blood spots or dry urine spots are often soaked in an organic solvent for long-time ultrasonic oscillation extraction in order to extract the trace substances, and the extracted solution is directly analyzed by an instrument after being separated. However, the content of trace substances in the dried blood spots and the dried urine spots obtained by traditional sampling is very low, and in order to obtain more accurate qualitative and quantitative results, the filter paper is stained with an anticoagulant in advance, so that the accuracy of the detection result can be improved.
The protective layer 1, the sample collection area 2 and the information collection area 3 are square, and the protective layer 1 and the sample collection area 2 have the same external dimension, so that the protective layer 1 can completely cover the sample collection area 2 after being folded, and blood and urine samples in the sample storage area 20 can be protected.
The protective layer 1 is transparent or semitransparent, a blood sampling card and a serial number character are printed on the protective layer 1, and the character is printed on one surface deviating from the sample collecting area 2.
In combination with the above, as shown in fig. 1 and fig. 2, the whole acquisition card (total length 18cm, width 5cm) is composed of three parts: the protective layer 1 is a cover (4.5cm multiplied by 5cm) which is printed with a blood sampling card and a turnover cover with a serial number character, and can protect the sample collection area 2 after being covered; a sample collection area 2, the size of which is 4.5cm multiplied by 5cm, the middle part of which is provided with double sampling rings, the diameter of each sampling ring is 12mm, two samples can be prepared simultaneously, and medium-speed quantitative filter paper (the filter paper is treated by 10 mu g/mL dipotassium ethylenediamine tetraacetate anticoagulant in advance, the thickness of the filter paper is 0.5mm +/-0.01 mm, and the ash content is 0.1% +/-0.001%); the information collecting area 3 can record information including name, sex, nationality, identity card number, household registration, current address and the like.
The acquisition card of the embodiment: the disposable volume of the blood and urine samples is 100-1000 mu L. The use method of the acquisition card comprises the following steps: a proper amount of blood or urine samples are taken by a pipettor, the two sample storage areas 20 in the sample collection area 2 are respectively dripped, sample information is filled in the information collection area 3, and after the samples are dried, the protective layer 1 is folded and covered for long-term storage for subsequent analysis.
The protective layer that the collection card of this utility mode set up can effectively protect dry blood spot and dry urine spot in the sample acquisition district, and the protection has the trace substance molecule that detects the meaning, improves qualitative and quantitative analysis's the result degree of accuracy. The anticoagulant can improve the solubility of dried blood and urine samples in the extracting solution and improve the accuracy of qualitative and quantitative analysis of trace substances in dry blood spots and dry urine spots. The acquisition card is convenient to use, free of environmental pollution and low in cost, and can be used for collecting and storing urine and blood samples so as to detect trace substances in dry urine spots and dry blood spots.
The above description is only some of the embodiments of the present invention, and the detailed description of the embodiments of the present invention is not intended to limit the scope of the present invention, but only to represent selected embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
Claims (10)
1. The collection card for the dry blood spots and the dry urine spots is characterized in that: the acquisition card comprises a protective layer (1), a sample acquisition area (2) and an information acquisition area (3) which are sequentially connected along the transverse direction; the protective layer (1) is foldable along a connection line between the protective layer (1) and the sample collection area (2) to cover the sample collection area (2); the sample collection area (2) comprises two separate sample retention areas (20).
2. The dry blood spot and dry urine spot collection card according to claim 1, wherein: each of the sample retention areas (20) is circular.
3. The dry blood spot and dry urine spot collection card according to claim 2, wherein: each sample holding area (20) is provided with a piece of filter paper containing an anticoagulant; each of the filter papers is a circle of the same size as the sample holding area.
4. The dry blood spot and dry urine spot collection card according to claim 3, wherein: the anticoagulant is ethylene diamine tetraacetic acid dipotassium salt.
5. The dry blood spot and dry urine spot collection card according to claim 3, wherein: each piece of filter paper is medium-speed quantitative filter paper.
6. The dry blood spot and dry urine spot collection card according to claim 3, wherein: two pieces of the filter paper are arranged in the sample collection area (2) along the longitudinal direction.
7. The dry blood spot and dry urine spot collection card according to claim 1, wherein: the protective layer (1), the sample collection area (2) and the information collection area (3) are square, and the protective layer (1) and the sample collection area (2) are identical in external dimension.
8. The dry blood spot and dry urine spot collection card according to claim 1, wherein: the total length of the acquisition card is 18cm, and the width of the acquisition card is 5 cm; wherein the protective layer (1) and the sample acquisition area (2) are both 4.5cm in length, and the information acquisition area (3) is 9cm in length; the width of the protective layer (1), the width of the sample collecting area (2) and the width of the information collecting area (3) are all 5 cm.
9. The dry blood spot and dry urine spot collection card according to claim 1, wherein: the protective layer (1) is transparent or semitransparent, and the protective layer (1) is printed with a typeface which is printed on the surface deviating from the sample collection area (2).
10. The dry blood spot and dry urine spot collection card according to claim 1, wherein: the information collecting area (3) is printed with characters of names, sexes, nationalities, identification numbers, household registers and current addresses.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120875327.9U CN214621846U (en) | 2021-04-26 | 2021-04-26 | Dry blood spot and dry urine spot collecting card |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120875327.9U CN214621846U (en) | 2021-04-26 | 2021-04-26 | Dry blood spot and dry urine spot collecting card |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214621846U true CN214621846U (en) | 2021-11-05 |
Family
ID=78405473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120875327.9U Expired - Fee Related CN214621846U (en) | 2021-04-26 | 2021-04-26 | Dry blood spot and dry urine spot collecting card |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214621846U (en) |
-
2021
- 2021-04-26 CN CN202120875327.9U patent/CN214621846U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211105 |
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| CF01 | Termination of patent right due to non-payment of annual fee |