CN214408997U - Kit for joint detection of infection projects - Google Patents

Kit for joint detection of infection projects Download PDF

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Publication number
CN214408997U
CN214408997U CN202022630016.4U CN202022630016U CN214408997U CN 214408997 U CN214408997 U CN 214408997U CN 202022630016 U CN202022630016 U CN 202022630016U CN 214408997 U CN214408997 U CN 214408997U
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detection
reagent
sample
reagent strip
pad
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芮兵
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Nanjing Baikang Biotechnology Co ltd
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Nanjing Baikang Biotechnology Co ltd
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Abstract

The utility model relates to a bedside short-term test technical field, concretely relates to joint detection infects kit of project, including the detection portion, the detection portion includes that a plurality of reagent strips and sample buffer memory fill up, and is a plurality of the reagent strip is rectangular form structure, and is a plurality of the reagent strip is word interval align to grid, and is a plurality of the reagent strip bottom all fills up with the sample buffer memory and is connected. The plurality of reagent strips are respectively a C-reactive protein reagent strip, a procalcitonin reagent strip and a serum amyloid A reagent strip. In the using process, the detection reagent is added into the sample buffer pad through the sample adding hole, waits for a moment, and analyzes the detection result through the observation window. The utility model discloses solved the bedside well and detected mostly single detection project, the operation is loaded down with trivial details relatively, the big scheduling problem of sample use amount.

Description

Kit for joint detection of infection projects
Technical Field
The utility model relates to a bedside short-term test technical field, concretely relates to joint detection infects kit of project outside the bed.
Background
Infectious diseases are common diseases in clinical medicine and are often accompanied by various complications. For most infectious diseases, accurate and timely detection of the etiology has great significance for accurate treatment, the morbidity characteristics of single infectious diseases are often not obvious, and the diagnosis requirement cannot be met only by depending on clinical symptoms, physical signs and imaging.
With the rapid development of in vitro diagnosis industry, serological detection items such as C-reactive protein (CRP), Procalcitonin (PCT) and Serum Amyloid A (SAA) are researched and applied more in the aspects of distinguishing infection degrees, distinguishing viral infection from bacterial infection, evaluating sepsis risks, guiding antibiotic medication and the like. Three inflammatory markers play corresponding respective advantages in the diagnosis and monitoring of different infectious diseases. The CRP and SAA combined detection items can effectively distinguish bacterial infection from viral infection in acute infectious diseases, the CRP index is obviously increased in bacterial infection and is not obvious in partial viral infection; the concentration level of the SAA index rises very quickly and greatly in bacterial infection, and the SAA index rises obviously in viral infection; the concentration level of the PCT index is not obviously increased when the PCT index is locally infected, the increase amplitude of the PCT index is large when the PCT index is seriously infected by severe bacteria and sepsis of the whole body, the risk degree of septic shock can be evaluated by monitoring the concentration level of the PCT index, the antibiotic is guided to be scientifically used, and the drug resistance caused by the abuse of the antibiotic is avoided.
Chinese patent with application number CN01242327.0 discloses a detect reagent box in biochemical detection field, including lid and box base, be equipped with a application of sample recess that link up on the lid, a plurality of observation holes and a plurality of application of sample hole, be equipped with the bellied test paper strip place the platform upwards that can place many test paper strips on the box base, can put a plurality of test paper strips of multiple different combination projects on the place the platform of box base, cover the lid, from the application of sample hole department application of sample, directly judge the result from observation hole department. The detection kit can detect a plurality of items simultaneously, does not need any instrument and equipment, has simple structure, low cost and simple and convenient operation, and can be widely used in the field of biochemical detection.
Present bedside detects CRP, PCT and SAA inflammation project and is mostly single detection project, and the operation is loaded down with trivial details relatively, and the sample use amount is big, the utility model provides a kit of joint detection infection project to solve above-mentioned problem.
SUMMERY OF THE UTILITY MODEL
To the above-mentioned weak point that exists among the prior art, the utility model provides a joint detection infects kit of project for solve the other detection of bed and mostly be single detection project, the operation is loaded down with trivial details relatively, the big scheduling problem of sample use amount.
In order to solve the technical problem, the utility model discloses a following technical scheme:
the utility model provides a kit of joint detection infection project, includes the detection portion, the detection portion includes a plurality of reagent strips and sample buffer pad, and is a plurality of the reagent strip is rectangular form structure, and is a plurality of the reagent strip is word interval align to grid, and is a plurality of the reagent strip bottom all is connected with sample buffer pad.
Furthermore, the plurality of reagent strips are respectively a C-reactive protein reagent strip, a procalcitonin reagent strip and a serum amyloid A reagent strip.
Further, the reagent strip includes absorbent paper, nitrocellulose membrane, sample pad and mark pad, absorbent paper folds and presses in the upper end of nitrocellulose membrane, the lower extreme at the nitrocellulose membrane is folded to the mark pad, the sample pad folds and presses in mark pad lower extreme top, sample pad end and sample buffer memory fill up to link up the coincidence.
Further, still include the box body, inside the box body was arranged in to the detection part, the inside edge of box body is equipped with a plurality of fixed columns, and is a plurality of the fixed column middle part is equipped with the fixed orifices, box body outer wall top is equipped with the joint groove.
The box cover is arranged at the top of the box body and is clamped with the box body, and the box cover comprises a plurality of observation windows, sample adding holes and mounting rods; the lid top is equipped with a plurality of observation windows, and is a plurality of the even interval arrangement of observation window, the lid bottom is arranged in to the application of sample hole, the inside edge of lid is equipped with a plurality of installation poles, and is a plurality of the installation pole is installed in the fixed orifices.
Furthermore, the lid still includes a plurality of antislip strips, and is a plurality of the even interval distribution of antislip strip is in the lid bottom.
Furthermore, the nitrocellulose membranes are coated with a quality control C line and a detection T line, the quality control C line is close to the absorbent paper, and the detection T line is close to the marking pad.
Compared with the prior art, the utility model, following beneficial effect has:
(1) the utility model discloses can detect three kinds of indexes of infection inflammation simultaneously, can effectively distinguish viral and bacterial infection, aassessment infection risk degree and guide the antibiotic to use medicine.
(2) The utility model is simple in operation, detect fast, a application of sample can obtain 3 testing results, is fit for the other short-term test demand of bed, has great using value in basic hospital.
(3) The utility model discloses an immunofluorescence chromatography technique, kit have sensitivity height, good reproducibility, result degree of accuracy characteristics such as high.
The utility model discloses solved the bedside well and detected mostly single detection project, the operation is loaded down with trivial details relatively, the big scheduling problem of sample use amount. The utility model discloses simple structure, convenient operation, reliable and stable.
Drawings
FIG. 1 is a schematic structural diagram of a box body in a kit for combined detection of infection projects according to the present invention;
FIG. 2 is a schematic view of a structure of a box cover of the kit for combined detection of infection projects according to the present invention;
reference numerals in the drawings of the specification include:
a box body 1; a fixed column 101; a clip groove 102; a box cover 2; a viewing window 201; a sample addition hole 202; a mounting rod 203; anti-slip strips 204; a detection unit 3; c-reactive protein reagent strip 301; procalcitonin reagent strips 302; serum amyloid a reagent strip 303; absorbent paper 304; a nitrocellulose membrane 305; a sample pad 306; a marking pad 307; a sample buffer pad 308.
Detailed Description
In order to make the present invention better understood by those skilled in the art, the technical solutions of the present invention are further described below with reference to the accompanying drawings and examples.
The first embodiment is as follows:
as shown in fig. 1-2, a kit for jointly detecting infection items includes a detection portion 3, the detection portion 3 includes a plurality of reagent strips and a sample buffer pad 308, the plurality of reagent strips are all strip-shaped structures, the plurality of reagent strips are uniformly arranged in a line at intervals, and bottoms of the plurality of reagent strips are connected with the sample buffer pad 308.
The utility model discloses be equipped with a plurality of reagent strips and be connected with sample buffer memory pad 308, examine time measuring, drip detect reagent on sample buffer memory pad 308, can realize that the application of sample can obtain 3 testing results once, easy operation, detection are quick, are fit for the other short-term test demand of bed, have great using value in basic hospital.
Preferably, the plurality of reagent strips are a C-reactive protein reagent strip 301, a procalcitonin reagent strip 302 and a serum amyloid A reagent strip 303.
The CRP and SAA combined detection items can effectively distinguish bacterial infection from viral infection in acute infectious diseases, the CRP index is obviously increased in bacterial infection and is not obvious in partial viral infection; the concentration level of the SAA index rises very quickly and greatly in bacterial infection, and the SAA index rises obviously in viral infection; the concentration level of the PCT index is not obviously increased when the PCT index is locally infected, the increase amplitude of the PCT index is large when the PCT index is seriously infected by severe bacteria and sepsis of the whole body, the risk degree of septic shock can be evaluated by monitoring the concentration level of the PCT index, the antibiotic is guided to be scientifically used, and the drug resistance caused by the abuse of the antibiotic is avoided.
Preferably, the reagent strip comprises absorbent paper 304, a nitrocellulose membrane 305, a sample pad 306 and a marking pad 307, wherein the absorbent paper 304 is laminated on the upper end of the nitrocellulose membrane 305, the marking pad 307 is laminated on the lower end of the nitrocellulose membrane 305, the sample pad 306 is laminated above the lower end of the marking pad 307, and the tail end of the sample pad 306 is jointed and coincided with a sample buffer pad 308. The nitrocellulose membranes 305 are coated with a quality control C line and a detection T line, the quality control C line is close to the absorbent paper 304, and the detection T line is close to the marking pad 307.
Dropping the reagent on the sample buffer pad 308, connecting the sample pad 306 with the nitrocellulose membrane 305, continuously attracting the reagent onto the nitrocellulose membrane 305 by the absorbent paper 304 at the top until the reagent covers the whole nitrocellulose membrane 305, and judging the detection result by the quality control C line and the detection T line.
Example two:
as shown in fig. 1-2, a kit for jointly detecting infection items includes a detection portion 3, the detection portion 3 includes a plurality of reagent strips and a sample buffer pad 308, the plurality of reagent strips are all strip-shaped structures, the plurality of reagent strips are uniformly arranged in a line at intervals, and bottoms of the plurality of reagent strips are connected with the sample buffer pad 308.
The utility model discloses be equipped with a plurality of reagent strips and be connected with sample buffer memory pad 308, examine time measuring, drip detect reagent on sample buffer memory pad 308, can realize that the application of sample can obtain 3 testing results once, easy operation, detection are quick, are fit for the other short-term test demand of bed, have great using value in basic hospital.
Preferably, the plurality of reagent strips are a C-reactive protein reagent strip 301, a procalcitonin reagent strip 302 and a serum amyloid A reagent strip 303.
The CRP and SAA combined detection items can effectively distinguish bacterial infection from viral infection in acute infectious diseases, the CRP index is obviously increased in bacterial infection and is not obvious in partial viral infection; the concentration level of the SAA index rises very quickly and greatly in bacterial infection, and the SAA index rises obviously in viral infection; the concentration level of the PCT index is not obviously increased when the PCT index is locally infected, the increase amplitude of the PCT index is large when the PCT index is seriously infected by severe bacteria and sepsis of the whole body, the risk degree of septic shock can be evaluated by monitoring the concentration level of the PCT index, the antibiotic is guided to be scientifically used, and the drug resistance caused by the abuse of the antibiotic is avoided.
Preferably, the reagent strip comprises absorbent paper 304, a nitrocellulose membrane 305, a sample pad 306 and a marking pad 307, wherein the absorbent paper 304 is laminated on the upper end of the nitrocellulose membrane 305, the marking pad 307 is laminated on the lower end of the nitrocellulose membrane 305, the sample pad 306 is arranged above the marking pad 307, and the tail end of the sample pad 306 is jointed and coincided with a sample buffer pad 308. The nitrocellulose membranes 305 are coated with a quality control C line and a detection T line, the quality control C line is close to the absorbent paper 304, and the detection T line is close to the marking pad 307.
Dropping the reagent on the sample buffer pad 308, connecting the sample pad 306 with the nitrocellulose membrane 305, continuously attracting the reagent onto the nitrocellulose membrane 305 by the absorbent paper 304 at the top until the reagent covers the whole nitrocellulose membrane 305, and judging the detection result by the quality control C line and the detection T line.
As preferred scheme, still include box body 1, inside detection portion 3 arranged box body 1 in, the inside edge of box body 1 was equipped with a plurality of fixed columns 101, and a plurality of fixed column 101 middle parts are equipped with the fixed orifices, and box body outer wall top is equipped with joint groove 102. The box cover 2 is arranged at the top of the box body 1, the box cover 2 is clamped with the box body 1, and the box cover 2 comprises a plurality of observation windows 201, sample adding holes 202 and mounting rods 203; 2 tops of lid are equipped with a plurality of observation windows 201, and a plurality of observation windows 201 are the even interval arrangement, and 2 bottoms of lid are arranged in to application of sample hole 202, and 2 inside edges of lid are equipped with a plurality of installation poles 203, and a plurality of installation poles 203 are installed in the fixed orifices.
Box body 1 provides accommodation space for detection portion 3, installation pole 203 and fixed column 101 joint, 2 inner walls of lid and joint groove 102 joints, and inspection window 201 can observe the testing process in real time.
Preferably, the box cover 2 further includes a plurality of anti-slip strips 204, and the plurality of anti-slip strips 204 are uniformly distributed at the bottom of the box cover 2 at intervals.
The anti-slip strips 204 provide contact points, improve the friction force of the box cover 2 and prevent the damage of the reagent box caused by the slip in the using process.
Advantages of the second embodiment over the first embodiment:
the detection efficiency and the detection accuracy of the kit are improved, the function of sampling at one time to obtain various results is realized to the maximum extent, and the detection sensitivity and the multiplexing rate of the kit are improved.
The use method of the kit comprises the following steps:
the detection reagent is added into the sample buffer pad 308 through the sample addition hole 202, and the detection result is observed through the observation window 201 after waiting for a moment.
In the description of the present invention, it is to be understood that the terms "front end", "rear end", "horizontal", "upper", "lower", "left", "right", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
The above description is only for the embodiments of the present invention, and the common general knowledge of the known specific structures and characteristics in the schemes is not described herein too much, and those skilled in the art will know all the common technical knowledge in the technical field of the present invention before the application date or the priority date, can know all the prior art in this field, and have the ability to apply the conventional experimental means before this date, and those skilled in the art can combine their own ability to perfect and implement the schemes, and some typical known structures or known methods should not become obstacles for those skilled in the art to implement the present application. It should be noted that, for those skilled in the art, without departing from the structure of the present invention, several modifications and improvements can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicability of the patent.

Claims (7)

1. A kit for the combined detection of infectious items, characterized in that: including measuring part (3), measuring part (3) include a plurality of reagent strips and sample buffer pad (308), and are a plurality of the reagent strip is rectangular form structure, and is a plurality of the reagent strip is word interval align to grid, and is a plurality of the reagent strip bottom all is connected with sample buffer pad (308).
2. The kit for the combined detection of infectious items according to claim 1, wherein: the plurality of reagent strips are respectively a C-reactive protein reagent strip (301), a procalcitonin reagent strip (302) and a serum amyloid A reagent strip (303).
3. The kit for the combined detection of infectious items according to claim 2, wherein: the reagent strip comprises absorbent paper (304), a nitrocellulose membrane (305), a sample pad (306) and a marking pad (307), wherein the absorbent paper (304) is laminated on the upper end of the nitrocellulose membrane (305), the marking pad (307) is laminated on the lower end of the nitrocellulose membrane (305), the sample pad (306) is laminated above the lower end of the marking pad (307), and the tail end of the sample pad (306) is jointed and coincided with a sample buffer pad (308).
4. The kit for the combined detection of infectious items according to claim 3, wherein: still include box body (1), inside box body (1) was arranged in to detection portion (3), box body (1) inside edge is equipped with a plurality of fixed columns (101), and is a plurality of fixed column (101) middle part is equipped with the fixed orifices, box body outer wall top is equipped with joint groove (102).
5. The kit for the combined detection of infectious items according to claim 4, wherein: the box cover is characterized by further comprising a box cover (2), wherein the box cover (2) is arranged at the top of the box body (1), the box cover (2) is clamped with the box body (1), and the box cover (2) comprises a plurality of observation windows (201), sample adding holes (202) and mounting rods (203); lid (2) top is equipped with a plurality of observation window (201), and is a plurality of observation window (201) evenly spaced apart, lid (2) bottom is arranged in to application of sample hole (202), lid (2) inside edge is equipped with a plurality of installation poles (203), and is a plurality of installation pole (203) are installed in the fixed orifices.
6. The kit for the combined detection of infectious items according to claim 5, wherein: the box cover (2) further comprises a plurality of anti-slip strips (204), and the anti-slip strips (204) are evenly distributed at the bottom of the box cover (2) at intervals.
7. The kit for the combined detection of infectious items according to claim 6, wherein: the cellulose nitrate membranes (305) are coated with a quality control C line and a detection T line, the quality control C line is close to the absorbent paper (304), and the detection T line is close to the marking pad (307).
CN202022630016.4U 2020-11-13 2020-11-13 Kit for joint detection of infection projects Active CN214408997U (en)

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CN202022630016.4U CN214408997U (en) 2020-11-13 2020-11-13 Kit for joint detection of infection projects

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115410653A (en) * 2022-08-31 2022-11-29 吉林金域医学检验所有限公司 Bacterial drug resistance monitoring method and device, computer equipment and storage medium

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115410653A (en) * 2022-08-31 2022-11-29 吉林金域医学检验所有限公司 Bacterial drug resistance monitoring method and device, computer equipment and storage medium
CN115410653B (en) * 2022-08-31 2023-10-17 吉林金域医学检验所有限公司 Bacterial drug resistance monitoring method, device, computer equipment and storage medium

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