CN214514421U - Dry granulating machine - Google Patents

Abstract

The utility model discloses a dry granulator. The dry granulating machine comprises a feeding mechanism, a granulating box body, an extruding mechanism, a crushing mechanism, a granulating mechanism and a sorting mechanism; feeding mechanism and pelletization box are connected in order to be used for to the internal feed of pelletization box, extrusion mechanism, broken mechanism and whole grain mechanism all are located the pelletization box and along material flow direction sequence distribution, extrusion mechanism is used for the extrusion to come from the material preparation shaping material of feeding mechanism, broken mechanism is used for the broken shaping material preparation broken material that comes from the extrusion mechanism, whole grain mechanism is used for grading broken material, sorting mechanism connects in whole grain mechanism in order to be used for sorting granule and the farine that comes from whole grain mechanism, the pelletization box has the compressed air interface, the compressed air interface is used for to the input compressed air of pelletization box. The dry-process granulator has high dry-pressing and granulating efficiency.

Description

Dry granulating machine

Technical Field

The utility model relates to a chemical industry, medicine field especially relate to a dry process granulator.

Background

At present, a dry granulating machine adopts a front box body to cover an extrusion mechanism, a crushing mechanism and a granulating mechanism, and can prevent dust from flying in the dry-pressing granulating process of materials to a certain extent. Although a sealing ring is added between the front box body and the box body, the material is still influenced by the humidity of the external environment air, so that the requirement of the humidity of a clean area required by the material cannot reach 45% -65%. For materials which are not easy to absorb moisture, the influence is small, and normal production can be realized; however, for materials which are easy to absorb moisture, water molecules in the air of the external environment are easy to absorb, so that the moisture content of the materials is increased, the fluidity is poor, the materials are bonded into blocks and adhered to the compression roller, the granulation rate of the formed pieces is low, and the production efficiency is reduced or even cannot be carried out. Simultaneously, because at the dry-pressing in-process, constantly have new material to continue to extrude through the compression roller, produce certain heat after long-time dry-pressing easily, then produce the hot melt easily to the material that contains sugar volume height, make the piece that extrudes become soft and become sticky, be difficult to be scraped by the scraper and glue on the compression roller, and because the piece that extrudes is too soft too sticky and also be difficult to be chopped up into the granule by whole grain wheel, lead to dry-pressing inefficiency, even the dry-pressing machine can't be moved down, cause production to stop production. Must shut down when above-mentioned condition and clear up the material of adhesion on the compression roller when appearing, the installation carries out dry pressing again, if the adhesion compression roller appears once more, then need clear the machine once more, the installation is repeated operation again, and the material that bonds the blocking after many times dry pressing is difficult to reuse basically, has not only caused the serious waste of material, still intangible greatly increased manufacturing cost, has reduced production efficiency.

SUMMERY OF THE UTILITY MODEL

Based on this, there is a need for a dry granulator. The dry granulating machine can avoid the condition that the materials are bonded into blocks and adhered to the compression roller to cause the abnormal production due to high air humidity of the external environment; meanwhile, the heat generated by long-time extrusion of the materials in the dry pressing process can be reduced, the situation that the materials with high sugar content and easy to melt when heated are softened and become sticky after being extruded is avoided, the dry pressing and granulating efficiency is improved, the material waste is avoided, and the production cost is reduced.

A dry granulating machine comprises a feeding mechanism, a granulating box body, an extruding mechanism, a crushing mechanism, a granulating mechanism and a sorting mechanism; the feeding mechanism is connected with the granulating box body and used for feeding materials into the granulating box body, the extruding mechanism, the crushing mechanism and the granulating mechanism are all positioned in the granulating box body and are sequentially distributed along the material flowing direction, the extrusion mechanism is used for extruding the material from the feeding mechanism to prepare the molding material, the crushing mechanism is used for crushing the molding material from the extrusion mechanism to prepare the crushed material, the sizing mechanism is configured to size the crushed material, the sorting mechanism is connected to the sizing mechanism and sorts the particles and the fine powder from the sizing mechanism, the granulation box body is provided with a compressed air interface, and the compressed air interface is used for inputting compressed air into the granulation box body so that the extrusion mechanism, the crushing mechanism, the granule finishing mechanism and the sorting mechanism in the granulation box body are in a dry and/or low-temperature micro-positive pressure environment.

In one embodiment, the dry granulator further comprises a first air compression mechanism in communication with the compressed air interface for inputting compressed air to the granulation tank;

and/or the extrusion mechanism comprises a first extrusion roller, a second extrusion roller and an extrusion driving component, the first extrusion roller and the second extrusion roller are arranged oppositely, an extrusion channel for the material to pass through is formed between the first extrusion roller and the second extrusion roller, the extrusion driving component is connected with the first extrusion roller and/or the second extrusion roller, and the extrusion driving component is used for driving the first extrusion roller and the second extrusion roller to rotate oppositely;

and/or the crushing mechanism comprises a crushing roller and a crushing driving part, the outer peripheral wall of the crushing roller is provided with a plurality of crushing teeth, the crushing driving part is connected with the crushing roller for driving the crushing roller to rotate, and the crushing roller is positioned at the discharge end of the extrusion mechanism;

and/or the granule adjusting mechanism includes a granule adjusting roller having a plurality of granule adjusting teeth on an outer peripheral wall thereof, and a granule adjusting driving member connected to the granule adjusting roller for driving the granule adjusting roller to rotate, the granule adjusting roller being positioned below the crushing mechanism.

In one embodiment, the dry granulator further comprises a scraping mechanism, the scraping mechanism comprises a first scraper and a second scraper, the first scraper and the second scraper are both installed in the granulation box body, the first scraper is matched with the first squeezing roller, and the second scraper is matched with the second squeezing roller;

the first scraper is located above the second scraper and is in contact fit with the first squeeze roll, the knife edge end of the second scraper is in contact fit with the second squeeze roll, and the knife tail end extends to the crushing mechanism.

In one embodiment, the granulating mechanism is provided with a plurality of granulating mechanisms which are distributed in the granulating box body in sequence along the vertical direction;

and/or the dry type granulator further comprises a feeding mechanism, wherein the feeding mechanism is connected between the feeding mechanism and the extrusion mechanism;

the feeding mechanism comprises a feeding box, a feeding roller and a feeding driving part, the feeding box is provided with a feeding input end and a feeding output end, the feeding output end faces the extrusion mechanism, the feeding roller is rotatably arranged in the feeding box and extends from the feeding input end to the feeding output end, and the driving part is connected to the feeding roller to drive the feeding roller to rotate.

In one embodiment, the dry granulator further comprises a return powder storage mechanism, wherein the return powder storage mechanism is communicated with the fine powder outlet of the sorting mechanism for recovering the fine powder;

the powder returning storage mechanism is further communicated with the feeding mechanism, a powder outlet of the powder returning storage mechanism is communicated with a second air compression mechanism, and the second air compression mechanism is used for conveying fine powder in the powder returning storage mechanism to the feeding mechanism or making the fine powder in the powder returning storage mechanism form a dry and/or low-temperature micro-positive pressure environment through compressed air.

In one embodiment, the dry granulator further comprises a new powder feeding mechanism, a feeding port of the new powder feeding mechanism is communicated with the feeding mechanism through a communicating pipe, the communicating pipe is spiral, a third air compression mechanism is connected to the feeding port, and the third air compression mechanism is used for conveying fine powder in the new powder feeding mechanism to the feeding mechanism through compressed air or enabling a dry and/or low-temperature micro-positive pressure environment to be formed in the new powder feeding mechanism through compressed air;

and/or, the dry granulator further comprises a vacuum feeding pump connected to the feeding mechanism for assisting in feeding;

and/or the sorting mechanism is a vibrating screen.

The dry-method granulator can avoid the situation that the materials are bonded into blocks and adhered to the compression roller to cause abnormal production due to high air humidity of the external environment; meanwhile, the heat generated by long-time extrusion of the materials in the dry pressing process can be reduced, the situation that the materials with high sugar content and easy to melt when heated are softened and become sticky after being extruded is avoided, the dry pressing and granulating efficiency is improved, the material waste is avoided, and the production cost is reduced. Specifically, the utility model discloses a dry process granulator passes through extrusion mechanism and extrudees the material extrusion, and the broken material that forms of rethread crushing mechanism is broken, and broken material obtains granule and farine after whole grain processing of whole grain mechanism, sorting mechanism are selected separately, and farine can get into back the powder and store mechanism recycle, has improved the utilization ratio of resource, in extrusion, breakage, whole grain, through an air compression mechanism to pelletization box input compressed air, compressed air accords with GMP requirement and humidity after dehumidification purification before letting in and is not more than 20% and/or the temperature is not higher than 20 ℃, can keep the microenvironment humidity in the pelletization box below 40%, has avoided the material to absorb moisture to appear bonding blocking, adhesion on the compression roller and lead to producing the condition emergence that can't go on.

The dry granulator of the utility model has the following beneficial effects.

(1) The utility model discloses let in the granulation box and purify through the dehumidification, accord with GMP (production of pharmaceuticals quality control standard) requirement, humidity is below 20% and/or the compressed air of temperature not more than 20 ℃, can keep the extrusion mechanism in the granulation box, broken mechanism, humidity is below 40% in the microenvironment of whole grain mechanism etc., this humidity is less than 45% ~ 65% humidity in traditional granulator, can prevent effectively that the material from absorbing moisture and appearing bonding blocking and adhesion on first squeeze roll and second squeeze roll, the condition that leads to producing unable going on takes place.

(2) The utility model discloses a set up back powder storage mechanism, can effectively retrieve the fine powder of selecting separately in the sorting mechanism, during the fine powder can directly get into feed mechanism again, perhaps gets into feed mechanism in the lump with the new powder in the new powder feed mechanism, pelletizes again, has improved the utilization ratio of resource, has avoided the waste of raw materials.

(3) The utility model discloses all let in through dehumidification purification, accord with GMP requirement, humidity in the compressed air below 8% in new powder feed mechanism, return powder storage mechanism, can keep humidity in the microenvironment in new powder feed mechanism, the return powder storage mechanism below 40%, prevent that the material from absorbing the moisture before the feeding and bonding the blocking, avoided the material to feed the condition emergence of difficulty, dry-pressing inefficiency.

(4) The utility model discloses let in the pelletization box through dehumidification purification, accord with GMP (pharmaceutical production quality control standard) requirement, humidity is below 20% and/or the temperature is not higher than 20 ℃ compressed air, can reduce the heat that produces because first squeeze roll and the long-time extrusion of second squeeze roll in the extrusion process, it softens the phenomenon that becomes sticky to avoid the high material extrusion of meeting heat fusible of sugar content to take place, the material after the extrusion is difficult to glue on first squeeze roll and second squeeze roll, the material extrusion can not be too soft too sticky, be cut into particles by whole grain wheel easily, dry pressing is efficient, effectively avoided the extravagant phenomenon of material, and the production cost is reduced.

(5) The utility model discloses a set up first scraper and second scraper in order to cooperate first squeeze roll and second squeeze roll respectively, scrape the material after the extrusion of adhesion on first squeeze roll and the second squeeze roll down, prevent that the phenomenon of the material adhesion after the extrusion from taking place.

Drawings

Fig. 1 is a schematic view of a dry granulator according to an embodiment of the present invention.

Description of the reference numerals

10. A dry granulator; 100. a granulation box body; 200. a feeding mechanism; 300. a feeding mechanism; 310. a feeding box; 311. a feed input; 312. a feed output end; 320. a feed roller; 400. a vacuum feed pump; 500. an extrusion mechanism; 510. a first squeeze roll; 520. a second squeeze roll; 600. a scraping mechanism; 610. a first scraper; 620. a second scraper; 700. a crushing mechanism; 800. a grading mechanism; 900. a sorting mechanism; 910. a particle outlet; 920. a fine powder outlet; 1000. a returned powder storage mechanism; 1010. a powder outlet; 1100. a new powder feeding mechanism; 1200. a first air compression mechanism; 1300. a second air compression mechanism; 1400. a third air compression mechanism; 1510. a first conduit; 1520. a second conduit; 1530. a communicating pipe; 1610. a first three-way valve; 1620. a second three-way valve; 1630. a third three-way valve; 1710. a first control valve; 1720. a second control valve; 1730. and a third control valve.

Detailed Description

In order to facilitate understanding of the present invention, the present invention will be described more fully hereinafter with reference to the accompanying drawings. The preferred embodiments of the present invention are shown in the drawings. The invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

In the description of the present invention, it should be understood that the terms used in the present invention are used in the description of the present invention, and it should be understood that the terms "center", "upper", "lower", "bottom", "inner", "outer" and the like used in the present invention are used as the terms of the orientation or the positional relationship shown in the drawings, and are only used for convenience of description and simplification of the description, but do not indicate or imply that the device or the element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be interpreted as limiting the present invention.

It should be understood that the terms "first", "second", etc. are used herein to describe various information, but the information should not be limited to these terms, and these terms are only used to distinguish one type of information from another. For example, "first" information may also be referred to as "second" information, and similarly, "second" information may also be referred to as "first" information, without departing from the scope of the present invention.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "connected" and "connected" are to be interpreted broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening elements, or they may be in communication within two elements, i.e., when an element is referred to as being "secured to" another element, it may be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

Referring to fig. 1, an embodiment of the present invention provides a dry granulation machine 10, which includes a granulation tank 100, a feeding mechanism 200, an extruding mechanism 500, a crushing mechanism 700, a granulating mechanism 800, and a sorting mechanism 900.

The feeding mechanism 200 is connected and communicated with the granulating tank 100, and the feeding mechanism 200 is used for conveying raw materials into the granulating tank 100.

The pressing mechanism 500, the crushing mechanism 700, and the granulating mechanism 800 are all provided in the granulating tank 100 and are sequentially distributed in the material flow direction. The pressing mechanism 500 is used to press the material from the feeding mechanism 200. The crushing mechanism 700 is used for crushing the molding material from the pressing mechanism 500 to obtain a crushed material. The sizing mechanism 800 is used to size the crushed material.

The sorting mechanism 900 is connected to the granulating mechanism 800 to sort the granules and the fine powder from the granulating mechanism 800. The sorting mechanism 900 has a particle outlet 910 and a fines outlet 920.

The granulation tank 100 has a compressed air inlet for inputting compressed air into the granulation tank 100 so that the pressing mechanism 500, the crushing mechanism 700, the granulating mechanism 800, and the sorting mechanism 900 in the granulation tank 100 are in a dry and/or low-temperature micro-positive pressure environment.

Preferably, the dry granulator 10 further comprises a first air compression mechanism 1200. The first air compression mechanism 1200 is in communication with the compressed air port of the granulation chamber 100 for inputting compressed air to the granulation chamber 100.

The dry granulator 10 introduces the dehumidified and purified compressed air meeting the GMP (good manufacturing practice) requirement and having a humidity within a predetermined value, such as below 20%, into the granulation box 100, so that the heat generated by long-time extrusion of the first extrusion roller 510 and the second extrusion roller 520 in the extrusion process can be reduced, the phenomenon that the extruded sugar content of the material which is high and is easily melted by heat is softened and sticky is avoided, the extruded material is not easily stuck to the first extrusion roller 510 and the second extrusion roller 520, the material is not too soft and sticky, the material is easily cut into granules by the granulating wheel, the dry pressing efficiency is high, the phenomenon of material waste is effectively avoided, and the production cost is reduced.

In one embodiment, the pressing mechanism 500 includes a first pressing roller 510, a second pressing roller 520, and a pressing driving part. The pressing drive is not shown in fig. 1. The first pressing roll 510 is disposed opposite to the second pressing roll 520, and a pressing channel for passing the material is formed between the first pressing roll 510 and the second pressing roll 520. The interval between the first pressing roll 510 and the second pressing roll 520 is adjustable. The extrusion driving part is installed in the granulating tank 100 and connected to the first extrusion roller 510 and the second extrusion roller 520, and the extrusion driving part is used for driving the first extrusion roller 510 and the second extrusion roller 520 to rotate towards each other. The pressing driving part may be a driving motor.

In one embodiment, the crushing mechanism 700 includes crushing rollers and a crushing drive component. The crushing drive member is not shown in fig. 1. The peripheral wall of the crushing roller has a plurality of crushing teeth, and the crushing drive unit is installed in the pelletization box 100 and is connected with the crushing roller for driving the crushing roller to rotate, and the crushing roller is located at the extrusion discharge end of the extrusion mechanism 500. The crushing drive member may be a drive motor.

In one embodiment, the sizing mechanism 800 includes a sizing roller and a sizing drive member. The granule-straightening drive is not shown in fig. 1. The outer peripheral wall of the granulating roller has a plurality of granulating teeth. The granule finishing driving means is installed in the granulation tank 100 and connected to the granule finishing roller for driving the granule finishing roller to rotate. The granule adjusting roller is located below the crushing mechanism 700.

In one embodiment, there are multiple grading mechanisms 800. The plurality of granulation units 800 are sequentially distributed in the vertical direction in the granulation tank 100. Referring to fig. 1, the number of the granulation mechanisms 800 is two, and the two granulation mechanisms 800 are distributed in the granulation tank 100 in the vertical direction.

In one embodiment, the dry granulator 10 further comprises a feed mechanism 300. The feeding mechanism 300 is connected between the feeding mechanism 200 and the pressing mechanism 500.

Preferably, the feeding mechanism 300 includes a feeding box 310, a feeding roller 320, and a feeding driving part. The feed drive components are not shown in figure 1. The feed magazine 310 has a feed input 311 and a feed output 312. The feed output 312 is directed toward the extrusion mechanism 500. The feeding roller 320 is rotatably disposed in the feeding box 310 and extends from the feeding input end 311 to the feeding output end 312, and the driving member is connected to the feeding roller 320 for driving the feeding roller 320 to rotate. The feed drive member may be a drive motor.

Further, the feeding box 310 is a column structure, the feeding box 310 is located outside the granulating tank 100, and the feeding output end 312 is communicated with the granulating tank 100. The feed roll 320 is a screw structure. When the feeding driving component drives the feeding roller 320 to rotate, the feeding driving component can drive the material at the feeding input end 311 to move towards the feeding output end 312.

In one embodiment, the dry granulator 10 further comprises a scraping mechanism 600. The scraping mechanism 600 includes a first scraper 610 and a second scraper 620, and the first scraper 610 and the second scraper 620 are both installed in the granulation tank 100. The first scraper 610 cooperates with the first pressing roll 510 to scrape off the materials adhered on the surface of the first pressing roll 510. The second doctor blade 620 is engaged with the second pressing roll 520. The utility model discloses a set up first scraper 610 and second scraper 620 in order to cooperate first squeeze roll 510 and second squeeze roll 520 respectively, scrape the material after the extrusion of adhesion on first squeeze roll 510 and the second squeeze roll 520, prevent that the phenomenon of the material adhesion after the extrusion from taking place.

Preferably, the first scraper blade 610 is positioned above the second scraper blade 620 and in contact engagement with the first squeeze roll 510, the nose end of the second scraper blade 620 is in contact engagement with the second squeeze roll 520 and the tail end extends to the crushing mechanism 700. The second blade 620 is located directly below the first blade 610. The second scraper 620 is provided in a diagonal shape in the granulating tank 100, and one end of the second scraper 620 remote from the second press roll 520 is inclined downward and extends to the granulating mechanism 800.

In one embodiment, the first air compression mechanism 1200 feeds compressed air to the granulation tank 100 with a humidity of no greater than 20%. For example, the humidity of the compressed air supplied to the granulation tank 100 by the first air compression mechanism 1200 is 20%, or the humidity of the compressed air supplied to the granulation tank 100 by the first air compression mechanism 1200 is 10%, or the humidity of the compressed air supplied to the granulation tank 100 by the first air compression mechanism 1200 is 5%. The utility model discloses let in pelletization box 100 through dehumidification purification, accord with the GMP requirement, humidity is at the compressed air below 20%, can keep extrusion mechanism 500 in the pelletization box 100, crushing mechanism 700, humidity is below 40% in the microenvironment of whole grain mechanism 800 etc., this humidity is less than 45% ~ 65% humidity in traditional granulator, can prevent effectively that the material from absorbing moisture and appearing bonding blocking and the adhesion is on first squeeze roll 510 and second squeeze roll 520, lead to the condition that production can't go on to take place.

In one embodiment, the dry granulator 10 further comprises a backsize storage mechanism 1000. The returned powder storage mechanism 1000 is connected to the sorting mechanism 900 for recovering the fine powder. Specifically, the returned powder storage mechanism 1000 is connected to the fine powder outlet 920 of the sorting mechanism 900. The returned powder storage mechanism 1000 may be a returned powder tank. The utility model discloses a set up back powder storage mechanism 1000, can effectively retrieve the fine powder that selects in sorting mechanism 900, during the fine powder can directly get into feed mechanism 200 again, perhaps gets into feed mechanism 200 with the new powder in the new powder feed mechanism 1100 in the lump, pelletizes again, has improved the utilization ratio of resource, has avoided the waste of raw materials.

In one embodiment, the powder outlet 1010 of the returned powder storage mechanism 1000 is also communicated with the feeding mechanism 200. The powder outlet 1010 of the powder return storage mechanism 1000 is communicated with a second air compression mechanism 1300, and the second air compression mechanism 1300 is used for conveying the fine powder in the powder return storage mechanism 1000 to the feeding mechanism 200 through compressed air or forming a dry and/or low-temperature micro-positive pressure environment in the powder return storage mechanism 1000 through compressed air. The humidity of the compressed air input from the second air compression mechanism 1300 is not higher than 8%.

Specifically, the returned powder storage mechanism 1000 is communicated with the feeding mechanism 200 through a first pipeline 1510. The second air compression mechanism 1300 is in communication with the first conduit 1510.

In one embodiment, the dry granulator 10 further includes a new powder feeding mechanism 1100, a feeding port of the new powder feeding mechanism 1100 is communicated with the feeding mechanism 200, a third air compression mechanism 1400 is connected to the feeding port, and the third air compression mechanism 1400 is used for conveying the fine powder in the new powder feeding mechanism 1100 to the feeding mechanism 200 by compressed air or enabling the new powder feeding mechanism 1100 to form a dry and/or low-temperature micro-positive pressure environment by compressed air. The humidity of the compressed air input from the third air compressing mechanism 1400 is not higher than 8%. The utility model discloses all let in through dehumidification purification, accord with GMP requirement, humidity in the compressed air below 8% in new powder feed mechanism 1100, return powder storage mechanism 1000, can keep humidity in the microenvironment in new powder feed mechanism 1100, the return powder storage mechanism 1000 below 40%, prevent that the material from absorbing the moisture before the feeding and bonding the blocking, avoided the material feeding difficulty, the condition emergence of dry-pressing inefficiency.

The new powder feeding mechanism 1100 communicates with the feeding mechanism 200 through the second pipe 1520. The third air compression mechanism 1400 is in communication with the second conduit 1520. Preferably, the first pipeline 1510 connected to the returned powder storage mechanism 1000 and the second pipeline 1520 connected to the new powder feeding mechanism 1100 are connected in parallel and then communicated with the feeding mechanism 200 through a communicating pipe 1530.

Further, in one embodiment, the first pipe 1510, the second pipe 1520, and the connection pipe 1530 are connected through the first three-way valve 1610.

Preferably, in one embodiment, the first line 1510 is connected to the returned powder storage mechanism 1000 by a third three-way valve 1630. The second pipe 1520 is connected to the new powder feeding mechanism 1100 by a second three-way valve 1620.

In one embodiment, a first control valve 1710 is disposed on a conduit between the first air compressing mechanism 1200 and the granulation tank 100. A second control valve 1720 is arranged on a pipeline between the powder outlet 1010 of the powder return storage mechanism 1000 and the powder return storage mechanism 1000. A third control valve 1730 is provided on the connection pipe 1530.

In one embodiment, the dry granulator 10 further comprises a vacuum feed pump 400, the vacuum feed pump 400 being connected to the feeding mechanism 200 for assisting in feeding.

In one embodiment, the sorting mechanism 900 is a shaker.

Preferably, in one embodiment, the communication pipe 1530 may have a spiral shape. The spiral communicating pipe 1530 is provided to maintain a certain height of the new powder or the fine powder entering the communicating pipe 1530 during the pulse-type feeding process of the returned powder storage mechanism 1000 or the new powder feeding mechanism 1100, so that the new powder or the fine powder rising along the communicating pipe 1530 at a certain height does not fall back when the pulse is intermittent, and the new powder or the fine powder rising at a certain height continues to enter the feeding mechanism 200 when the pulse is next time.

The dry granulator 10 of the utility model can avoid the situation that the material is bonded into blocks due to high air humidity of the external environment and is adhered to the compression roller, so that the production can not be carried out; meanwhile, the heat generated by long-time sheet extrusion of the compression roller in the dry pressing process can be reduced, the situation that the sheet becomes soft and sticky when the sugar content of the material which is high and is easily melted when being heated is avoided, the dry pressing efficiency is improved, the material waste is prevented, and the production cost is reduced. Specifically, the utility model discloses a dry process granulator 10 is through 500 material extrusion of extrusion mechanism, the broken material that forms of rethread crushing mechanism 700, broken material is through whole grain processing of whole grain mechanism 800, sorting mechanism 900 selects separately the back and obtains granule and farine, farine can get into back the powder and store 1000 recycle of mechanism, the utilization ratio of resource has been improved, at the extrusion, it is broken, whole grain in, through an air compression mechanism 1200 to pelletization box 100 input compressed air, compressed air accords with GMP requirement and humidity and is not more than 20% after dehumidifying and purifying before letting in, can keep the microenvironment humidity in pelletization box 100 below 40%, avoided the material to absorb moisture the appearance and bond the blocking, the adhesion is on the compression roller and lead to producing the condition emergence that can't go on.

An embodiment of the present invention further provides a dry granulation method using the dry granulator 10. The dry granulation method comprises the following steps:

a dry granulation process comprising the steps of:

the material is fed into the granulation tank 100 through the feeding mechanism 200, the first air compression mechanism 1200 or an external air source (the external air source may be a self-contained air source system in a pharmaceutical factory or a workshop) is controlled to input compressed air into the granulation tank 100, so that the extrusion mechanism 500, the crushing mechanism 700, the granulating mechanism 800 and the sorting mechanism 900 in the granulation tank 100 are in a dry and/or low-temperature micro-positive pressure environment, the humidity of the compressed air input into the granulation tank 100 is not more than 20%, and/or the temperature of the compressed air input into the granulation tank 100 is not more than 20 ℃.

The material is extruded by an extrusion mechanism 500 to produce a shaped material.

The molding material is crushed by a crushing mechanism 700 to prepare a crushed material.

The crushed material is granulated by the granulation mechanism 800.

The sorting mechanism 900 is controlled to sort the granules and the fine powder from the granule sorting mechanism 800.

In one embodiment, the temperature of the compressed air input to the granulation tank 100 is 10 ℃ to 20 ℃. For example, the first air compression mechanism 1200 may supply compressed air to the granulation tank 100 at a temperature of 10 ℃, 11 ℃, 15 ℃, 17 ℃, 20 ℃ or other values.

In one embodiment, the dry granulation process further comprises the steps of: controlling the second air compression mechanism 1300 or an external air source (the external air source can be a self-contained air source system in a pharmaceutical factory or a workshop) to introduce compressed air into the returned powder storage mechanism 1000, wherein the humidity of the compressed air input into the returned powder storage mechanism 1000 is not more than 8%, and/or the temperature of the compressed air input into the returned powder storage mechanism 1000 is not higher than 20 ℃, and fine powder in the sorting mechanism 900 enters the returned powder storage mechanism 1000.

Preferably, the temperature of the compressed air input to the returned powder storage mechanism 1000 is 10 ℃ to 20 ℃. For example, the temperature of the compressed air supplied to the returned powder storage means 1000 may be 10 ℃, 11 ℃, 15 ℃, 17 ℃, 20 ℃ or other values.

In one embodiment, the dry granulation process further comprises the steps of: controlling the third air compression mechanism 1400 or an external air source (the external air source can be a self-contained air source system in a pharmaceutical factory or a workshop) to input compressed air into the new powder feeding mechanism 1100, wherein the humidity of the compressed air input into the new powder feeding mechanism 1100 is not more than 8%, and/or the temperature of the compressed air input into the new powder feeding mechanism 1100 is not higher than 20 ℃, and new powder in the new powder feeding mechanism 1100 and/or fine powder in the returned powder storage mechanism 1000 flow back to the feeding mechanism 200.

Preferably, the temperature of the compressed air input to the fresh powder feeding mechanism 1100 is 10-20 ℃. For example, the temperature of the compressed air input to the fresh powder feeding mechanism 1100 may be 10 ℃, 11 ℃, 15 ℃, 17 ℃, 20 ℃ or other values.

Example 1

The present embodiment provides a dry granulator 10. The dry granulation machine 10 is used for dry granulation of the lobelia extract which is easy to absorb moisture.

Referring to fig. 1, a dry granulator 10 includes a granulation tank 100, a feeding mechanism 200, a feeding mechanism 300, a vacuum feeding pump 400, an extruding mechanism 500, a scraping mechanism 600, a crushing mechanism 700, a granulating mechanism 800, a sorting mechanism 900, a powder returning and storing mechanism 1000, a new powder feeding mechanism 1100, and a first air compressing mechanism 1200.

The feeding mechanism 200 is connected and communicated with the granulating tank 100, and the feeding mechanism 200 is used for conveying raw materials into the granulating tank 100. A vacuum feed pump 400 is connected to the feed mechanism 200 for auxiliary feeding.

The pressing mechanism 500, the crushing mechanism 700, and the granulating mechanism 800 are all provided in the granulating tank 100 and distributed in order. The pressing mechanism 500 is used to press the material from the feeding mechanism 200. The crushing mechanism 700 is used for crushing the molding material from the pressing mechanism 500 to obtain a crushed material. The sizing mechanism 800 is used to size the crushed material.

The feeding mechanism 300 is connected between the feeding mechanism 200 and the pressing mechanism 500. The feeding mechanism 300 includes a feeding cassette 310, a feeding roller 320, and a feeding driving part. The feed magazine 310 has a feed input 311 and a feed output 312. The feed output 312 is directed toward the extrusion mechanism 500. The feeding roller 320 is rotatably disposed in the feeding box 310 and extends from the feeding input end 311 to the feeding output end 312, and the driving member is connected to the feeding roller 320 for driving the feeding roller 320 to rotate. The feeding box 310 is a columnar structure, the feeding box 310 is located outside the granulating box 100, and the feeding output end 312 is communicated with the granulating box 100. The feed roll 320 is a screw structure. When the feeding driving component drives the feeding roller 320 to rotate, the feeding driving component can drive the material at the feeding input end 311 to move towards the feeding output end 312.

The sorting mechanism 900 is connected to the granulating mechanism 800 to sort the granules and the fine powder from the granulating mechanism 800. The sorting mechanism 900 has a particle outlet 910 and a fines outlet 920. The sorting mechanism 900 is a shaker.

The first air compression mechanism 1200 is connected to and communicates with the granulation tank 100 for inputting compressed air to the granulation tank 100. The first air compressing mechanism 1200 inputs the compressed air which is dehumidified and purified, meets GMP requirements, has a humidity of 10% and is cooled to 15 ℃ into the granulating tank 100.

The pressing mechanism 500 includes a first pressing roller 510, a second pressing roller 520, and a pressing driving part. The first pressing roll 510 is disposed opposite to the second pressing roll 520, and a pressing channel for passing the material is formed between the first pressing roll 510 and the second pressing roll 520. The interval between the first pressing roll 510 and the second pressing roll 520 is adjustable. The extrusion driving part is installed in the granulating tank 100 and connected to the first extrusion roller 510 and the second extrusion roller 520, and the extrusion driving part is used for driving the first extrusion roller 510 and the second extrusion roller 520 to rotate towards each other.

The scraping mechanism 600 includes a first scraper 610 and a second scraper 620, and the first scraper 610 and the second scraper 620 are both installed in the granulation tank 100. The first doctor blade 610 is engaged with the first pressing roll 510. The second doctor blade 620 is engaged with the second pressing roll 520. The first scraper blade 610 is located above the second scraper blade 620 and is in contact fit with the first squeeze roll 510, the edge end of the second scraper blade 620 is in contact fit with the second squeeze roll 520, and the edge end extends to the crushing mechanism 700. The second blade 620 is located directly below the first blade 610. The second scraper 620 is provided in a diagonal shape in the granulating tank 100, and one end of the second scraper 620 remote from the second press roll 520 is inclined downward and extends to the granulating mechanism 800.

The crushing mechanism 700 includes crushing rollers and a crushing drive component. The peripheral wall of the crushing roller has a plurality of crushing teeth, and the crushing drive unit is installed in the pelletization box 100 and is connected with the crushing roller for driving the crushing roller to rotate, and the crushing roller is located at the extrusion discharge end of the extrusion mechanism 500.

The sizing mechanism 800 includes a sizing roller and a sizing driving means. The outer peripheral wall of the granulating roller has a plurality of granulating teeth. The granule finishing driving means is installed in the granulation tank 100 and connected to the granule finishing roller for driving the granule finishing roller to rotate. The granule adjusting roller is located below the crushing mechanism 700.

The number of the granulation mechanisms 800 is two, and the two granulation mechanisms 800 are distributed in the granulation tank 100 in the vertical direction.

The returned powder storage mechanism 1000 is connected to the sorting mechanism 900 for recovering the fine powder. Specifically, the returned powder storage mechanism 1000 is connected to the fine powder outlet 920 of the sorting mechanism 900. The returned powder storage mechanism 1000 is communicated with the feeding mechanism 200 through a first pipeline 1510. The powder outlet 1010 of the powder return storage mechanism 1000 is communicated with a second air compression mechanism 1300, and the second air compression mechanism 1300 is used for conveying the fine powder in the powder return storage mechanism 1000 to the feeding mechanism 200 through compressed air. The air input by the second air compression mechanism 1300 is the compressed air which is dehumidified and purified, meets the GMP requirement, has the humidity of 10% and is cooled to 15 ℃. The second air compression mechanism 1300 is in communication with the first conduit 1510.

The feeding port of the new powder feeding mechanism 1100 is communicated with the feeding mechanism 200 through a second pipeline 1520, the second pipeline 1520 is connected with a third air compression mechanism 1400 in a communicating manner, and the third air compression mechanism 1400 is used for conveying fine powder in the new powder feeding mechanism 1100 to the feeding mechanism 200 through compressed air. The air input by the third air compression mechanism 1400 is the compressed air which is dehumidified and purified, meets the GMP requirement, has the humidity of 10% and is cooled to 15 ℃. The first pipeline 1510 connected to the returned powder storage mechanism 1000 and the second pipeline 1520 connected to the new powder feeding mechanism 1100 are connected in parallel and then communicated with the feeding mechanism 200 through a communicating pipe 1530.

Example 2

The present embodiment provides a dry granulator 10.

The dry granulation machine 10 of this example was used to dry granulate the material Lobelia chinensis extract, which is moisture-absorbent. The present embodiment adopts the dry granulator 10 according to embodiment 1, and is different from embodiment 1 in that in the present embodiment, the air input from the first air compression mechanism 1200, the second air compression mechanism 1300, and the third air compression mechanism 1400 is dehumidified and purified, and the compressed air meets the GMP requirement and has a humidity of 10%.

Example 3

The present embodiment provides a dry granulator 10.

The dry granulation machine 10 of this example was used to dry granulate the material Lobelia chinensis extract, which is moisture-absorbent. The present embodiment adopts the dry granulator 10 of embodiment 1, and is different from embodiment 1 in that in this embodiment, the air input from the first air compressing mechanism 1200 is dehumidified and purified, and is compressed air with a humidity of 10% and meeting GMP requirements. The second air compression mechanism 1300 and the third air compression mechanism 1400 do not input and compress air.

Example 4

The present embodiment provides a dry granulator 10.

The dried orange peel extract, which has a high sugar content and is easily melted, is dry-granulated by using the dry granulator 10 of this example. In this embodiment, the dry granulator 10 of embodiment 1 is used, and the difference from embodiment 1 is that in this embodiment, the air input by the first air compression mechanism 1200, the second air compression mechanism 1300, and the third air compression mechanism 1400 is dehumidified and purified, and is compressed air which meets GMP requirements, has a humidity of 10%, and is cooled to 15 ℃.

Example 5

The present embodiment provides a dry granulator 10.

The dried orange peel extract, which has a high sugar content and is easily melted, is dry-granulated by using the dry granulator 10 of this example. The embodiment adopts the dry granulator 10 of embodiment 1, and is different from embodiment 1 in that in this embodiment, the air input by the first air compression mechanism 1200, the second air compression mechanism 1300, and the third air compression mechanism 1400 is dehumidified and purified, and the compressed air meets GMP requirements, has a humidity of 10%, and is cooled to 20 ℃.

Example 6

The present embodiment provides a dry granulator 10.

The dried orange peel extract, which has a high sugar content and is easily melted, is dry-granulated by using the dry granulator 10 of this example. In this embodiment, the dry granulator 10 of embodiment 1 is used, and the difference from embodiment 1 is that in this embodiment, the air input by the first air compression mechanism 1200 is all dehumidified and purified, and is compressed air which meets GMP requirements, has a humidity of 20%, and is cooled to 20 ℃. The second air compression mechanism 1300 and the third air compression mechanism 1400 do not input and compress air.

Comparative example 1

The comparative example adopts a conventional dry granulation machine in the prior art to perform dry granulation on the lobelia extract which is easy to absorb moisture.

Comparative example 2

The comparative example adopts a conventional dry granulation machine in the prior art to perform dry granulation on the dried orange peel extract which has high sugar content and is easy to melt.

The dry pressing efficiencies and the water contents of the produced pellets in examples 1 to 6 and comparative examples 1 to 2 were counted, and the results are shown in table 1, wherein the dry pressing efficiency improvement rate is ((example dry pressing efficiency-comparative example dry pressing efficiency)/comparative example dry pressing efficiency) × 100%.

TABLE 1 Dry pressing of the granules

Can know by embodiment 1 ~ 6 and comparison 1 ~ 2 comparison, the utility model provides a dry process granulator 10 can control the humiture of environment effectively, forms dry, microthermal, stable microenvironment to obviously improve the material dry pressure efficiency of easy moisture absorption or sugar content height, easy hot melt.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only represent some embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

Claims (10)

1. A dry granulator is characterized by comprising a feeding mechanism, a granulating box body, an extruding mechanism, a crushing mechanism, a granule finishing mechanism and a sorting mechanism; the feeding mechanism is connected with the granulating box body and used for feeding materials into the granulating box body, the extruding mechanism, the crushing mechanism and the granulating mechanism are all positioned in the granulating box body and are sequentially distributed along the material flowing direction, the extrusion mechanism is used for extruding the material from the feeding mechanism to prepare the molding material, the crushing mechanism is used for crushing the molding material from the extrusion mechanism to prepare the crushed material, the sizing mechanism is configured to size the crushed material, the sorting mechanism is connected to the sizing mechanism and sorts the particles and the fine powder from the sizing mechanism, the granulation box body is provided with a compressed air interface, and the compressed air interface is used for inputting compressed air into the granulation box body so that the extrusion mechanism, the crushing mechanism, the granule finishing mechanism and the sorting mechanism in the granulation box body are in a dry and/or low-temperature micro-positive pressure environment.

2. The dry granulator of claim 1 further comprising a first air compression mechanism in communication with the compressed air port for inputting compressed air to the granulation tank;

and/or the extrusion mechanism comprises a first extrusion roller, a second extrusion roller and an extrusion driving component, the first extrusion roller and the second extrusion roller are arranged oppositely, an extrusion channel for the material to pass through is formed between the first extrusion roller and the second extrusion roller, the extrusion driving component is connected with the first extrusion roller and/or the second extrusion roller, and the extrusion driving component is used for driving the first extrusion roller and the second extrusion roller to rotate oppositely;

and/or the crushing mechanism comprises a crushing roller and a crushing driving part, the outer peripheral wall of the crushing roller is provided with a plurality of crushing teeth, the crushing driving part is connected with the crushing roller for driving the crushing roller to rotate, and the crushing roller is positioned at the discharge end of the extrusion mechanism;

and/or the granule adjusting mechanism includes a granule adjusting roller having a plurality of granule adjusting teeth on an outer peripheral wall thereof, and a granule adjusting driving member connected to the granule adjusting roller for driving the granule adjusting roller to rotate, the granule adjusting roller being positioned below the crushing mechanism.

3. The dry granulator of claim 2 further comprising a scraping mechanism comprising a first scraper and a second scraper, the first scraper and the second scraper both mounted within the granulation tank, the first scraper engaged with the first squeeze roll, the second scraper engaged with the second squeeze roll;

the first scraper is located above the second scraper and is in contact fit with the first squeeze roll, the knife edge end of the second scraper is in contact fit with the second squeeze roll, and the knife tail end extends to the crushing mechanism.

4. The dry granulator according to any one of claims 1 to 3 wherein the granulation mechanism has a plurality of granulation mechanisms, and the plurality of granulation mechanisms are sequentially distributed in the vertical direction in the granulation tank.

5. The dry granulator according to any of claims 1-3 further comprising a feeding mechanism connected between the feeding mechanism and the extrusion mechanism;

the feeding mechanism comprises a feeding box, a feeding roller and a feeding driving part, the feeding box is provided with a feeding input end and a feeding output end, the feeding output end faces the extrusion mechanism, the feeding roller is rotatably arranged in the feeding box and extends from the feeding input end to the feeding output end, and the driving part is connected to the feeding roller to drive the feeding roller to rotate.

6. The dry granulator according to any of claims 1 to 3 further comprising a return fines storage means in communication with the fines outlet of the classifying means for recovering the fines.

7. The dry granulator of claim 6 wherein the powder return storage mechanism is further communicated with the feeding mechanism, and a powder outlet of the powder return storage mechanism is communicated with a second air compression mechanism, and the second air compression mechanism is used for conveying the fine powder in the powder return storage mechanism to the feeding mechanism by compressed air or forming a dry and/or low-temperature micro-positive pressure environment in the powder return storage mechanism by compressed air.

8. The dry granulator according to any one of claims 1 to 3 further comprising a new powder feeding mechanism, wherein a feeding port of the new powder feeding mechanism is communicated with the feeding mechanism through a communicating pipe, the communicating pipe is spiral, a third air compression mechanism is connected to the feeding port, and the third air compression mechanism is used for conveying fine powder in the new powder feeding mechanism to the feeding mechanism through compressed air or enabling a dry and/or low-temperature micro-positive pressure environment to be formed in the new powder feeding mechanism through compressed air.

9. The dry granulator according to any of claims 1-3 further comprising a vacuum feed pump connected to the feeding mechanism for assisting feeding.

10. The dry granulator according to any of claims 1 to 3 wherein the sorting mechanism is a vibrating screen.

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