CN214503260U - Device for researching evolution of virus aerosol in atmosphere - Google Patents
Device for researching evolution of virus aerosol in atmosphere Download PDFInfo
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- CN214503260U CN214503260U CN202023043789.9U CN202023043789U CN214503260U CN 214503260 U CN214503260 U CN 214503260U CN 202023043789 U CN202023043789 U CN 202023043789U CN 214503260 U CN214503260 U CN 214503260U
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- aerosol
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- atmosphere
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Images
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a device for researching evolution of virus aerosol in atmosphere, which comprises an aerosol introduction module, an aerosol simulated evolution module and an aerosol measurement module; the aerosol introducing module comprises a sample introduction cabin, an aerosol generator, a nitrogen source and a simulation air source; the aerosol simulated evolution module comprises a roller and a driving device for driving the roller to rotate; the aerosol measurement module comprises a sample outlet bin, a temperature and humidity probe, an aerosol detection device and air filtrationA device. The device for researching the evolution of the virus aerosol in the atmosphere can comprehensively investigate the meteorological conditions (temperature, humidity and illumination) and the atmospheric environmental conditions (including the oxidizing substances in the atmosphere, such as O)3,NOx,SO2OH free radical, etc.) and the physical and chemical properties of the stored particles on the physical characteristics and the infection activity of the virus aerosol, and is more suitable for the evolution research of the virus aerosol in the atmosphere.
Description
Technical Field
The utility model relates to a device for studying evolution of virus aerosol in atmosphere.
Background
The virus aerosol transmission has the characteristics of high transmission speed, wide infection range, high prevention and control difficulty and the like, is easy to cause major public health accidents, and generates major life and economic losses. The effective prevention and control of epidemic situations is undoubtedly a major challenge facing human beings, the key of the prevention and control of the epidemic situations is to block a transmission way, aerosol transmission is used as a transmission way, and the intensive research on the important scientific problems can provide theoretical and scientific support for the effective prevention and control of the serious epidemic situations in the future.
Aerosol transmission is one of the potential transmission paths of viruses, and the occurrence condition, the influence range and the change rule of the virus infection capacity in the transmission process are important scientific problems facing the actual requirements of the virus aerosol transmission path prevention and control. It has been shown that atmospheric environmental and meteorological factors may affect the spread and activity changes of viral Aerosols (Kormuth, K.A.; Lin, K.; Prussin, A.J., II; Vejerano, E.P.; Tiwari, A.J.; Cox, S.S.; Myerburg, M.M.; Lakdawala, S.S.; Marr, L.C., Influenza Virus infection in microorganisms and impurities introduction of Relative humidity. the Journal of infection Diseases 2018,218, (5), 739. 747), (Pani, S.K.; Lin N.H.; ravindrabangbu, S.S., Association of Cooperation 19. weather, Science, III. and filtration of microorganism, microorganism of animal 112, microorganism of animal of Japan, animal of Japan, No. 112, animal of Japan, No. 112, animal of Japan, No. 112, No. 7, animal of, No. 7, vitamin, No. 7, No.. However, only a few laboratories in the world currently have simulated research devices for the evolution of viral aerosols in the atmosphere. In addition, The devices for researching The evolution rule of The virus aerosol in The atmosphere only consider The regulation and control of The temperature and humidity (Marr, L.C.; Tang, J.W.; Van Mullekom, J.; Lakdawala, S.S., mechanical inertia in The effect of humidity on air in fluorine virus measure and maintain, transmission and intake, Journal of The Royal Society Interface 2019,16, (150),20180298), and The actual atmospheric conditions (such as illumination, temperature, humidity, atmospheric oxidant, etc.) are still difficult to be considered comprehensively.
Therefore, designing a simulation device which can be used for researching the evolution rule of the virus aerosol and the infection activity thereof in the atmosphere has important significance for deeply researching aerosol transmission and activity influence factors of the virus.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a device for studying evolution of virus aerosol in the atmosphere can study the evolution law of virus aerosol and infectious activity in the atmosphere.
In order to achieve the above object, the utility model adopts the following technical scheme:
a device for researching evolution of virus aerosol in atmosphere comprises an aerosol introduction module, an aerosol simulated evolution module and an aerosol measurement module;
the aerosol introducing module comprises a sample introduction cabin, an aerosol generator, a nitrogen source and a simulation air source; the aerosol simulated evolution module comprises a roller and a driving device for driving the roller to rotate; the aerosol measurement module comprises a sample outlet bin, a temperature and humidity probe, an aerosol detection device and an air filter;
the sample feeding bin and the sample discharging bin are horizontally fixed on the bracket at intervals, and the roller is rotatably arranged between the sample feeding bin and the sample discharging bin and is communicated with the sample feeding bin and the sample discharging bin; the simulation air source is connected with the sample injection bin, the nitrogen source is divided into two paths, one path is directly connected with the sample injection bin, and the other path is connected with the sample injection bin through the aerosol generator; the temperature and humidity probe is arranged on the sample outlet bin, and the aerosol detection device and the air filter are respectively connected with the sample outlet bin.
Furthermore, the sample feeding bin is provided with a heating module which can be used for controlling the temperature of the inlet airflow.
Furthermore, the sample feeding bin or the cover plate at the end part of the roller are made of transparent materials, and a simulated solar light source is arranged outside the device and used for simulating atmospheric illumination conditions.
Further, the inner wall of the roller is provided with a Teflon coating. The Teflon material has the characteristics of high temperature resistance, corrosion resistance, non-adhesion, no toxicity and the like, can reduce the wall loss, prevent the roller from being corroded under the simulated high humidity condition, and prevent the base effect influencing the activity of the virus aerosol from being generated under the exposure conditions of high humidity, high oxidation, illumination and the like.
The device of the utility model is used for researching the occurrence state and the infection activity of the virus aerosol in the atmosphere, and investigating the meteorological conditions (temperature, humidity and illumination) and the atmospheric environmental conditions including the oxidizing substances (such as O) in the atmosphere3,NOx,SO2OH radicals, etc.) and existing particulate matter physicality on the physical characteristics of the viral aerosol and the infectious activity.
Compared with the prior art, its beneficial effect is:
1. not only the temperature and humidity which influence the activity of the virus aerosol are considered, but also the illumination, atmospheric oxidation, existing aerosol particles and the like are considered.
2. The Teflon material coating adopted by the inner wall of the roller has the characteristics of high temperature resistance, corrosion resistance, non-adhesion, no toxicity and the like, can avoid the basal effect which influences the activity of the virus aerosol under the conditions of high humidity, high oxidability, illumination and the like, reduces the loss in the simulation process, and is more suitable for the evolution research of the virus aerosol in the atmosphere.
Drawings
Fig. 1 is a schematic view of the overall structure of the device disclosed by the present invention.
Description of reference numerals: 1-a roller; 2-sample introduction chamber; 3, discharging a sample bin; 4-a simulated air source; a source of 5-nitrogen; 6-aerosol generator; 7-a temperature and humidity probe; 8-aerosol detection means; 9-an air filter; 10-a stent.
Detailed Description
The technical solutions of the present application will be described clearly and completely with reference to the accompanying drawings in the embodiments, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
In the description of the present application, it is to be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the present application and for simplicity in description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the present application.
Referring to fig. 1, a device for studying viral aerosol evolution in the atmosphere mainly includes an aerosol introduction module, an aerosol simulated evolution module, and an aerosol measurement module.
The aerosol simulated evolution module mainly comprises a hollow cylindrical roller 1 and a driving device (not shown in the figure) for driving the roller 1 to rotate so as to simulate the evolution of virus aerosol under the condition of manually setting atmospheric environment, and the aerosol loss is reduced to the minimum by controlling the rotating speed of the roller 1.
The roller 1 is preferably made of aluminum, the inner diameter of the roller is about 40 cm, the length of the roller is about 80 cm, and the inner part of the roller 1 is coated with a coating made of Teflon material, so that the wall loss can be reduced, the roller is prevented from being corroded under simulated high humidity conditions, and the base effect influencing the activity of virus aerosol is prevented from being generated under the conditions of high humidity, high oxidation, illumination and the like.
The specific structure of the driving module may be realized by a conventional technical means, for example, the drum 1 may be driven to rotate by a motor + belt transmission, a motor + gear transmission, which is not described herein.
The aerosol introducing module mainly comprises a sample introduction cabin 2, a simulated air source 4, a nitrogen source 5 and an aerosol generator 6. The aerosol measurement module mainly comprises a sample outlet bin 3, a temperature and humidity probe 7, an aerosol detection device 8 and an air filter 9.
The sample feeding bin 2 and the sample discharging bin 3 are horizontally fixed on the support 10 at intervals, the roller 1 is rotatably installed between the sample feeding bin 2 and the sample discharging bin 3 and is communicated with each other, and the rotary connection mode can adopt conventional modes such as O-ring dynamic seal, circular slide rail and the like, and the details are not repeated.
The simulation air source 4 is connected with the sample injection bin 2 through a pipeline, the nitrogen source 5 is divided into two paths, one path is directly connected with the sample injection bin 2 through the pipeline, and the other path is connected with the sample injection bin 2 through the aerosol generator 6 through the pipeline. The simulated air source 4 comprises pure dry air and an oxidant, and can be specifically configured according to experimental requirements, for example, humidity in the drum 1 can be controlled by configuring different proportions of the dry air and the nitrogen, and different configurations of the simulated air can be realized by controlling the concentration of the oxidant. An aerosol generator 6 is commercially available, which produces droplets of virus carried into the drum 1 by a nitrogen gas stream.
Preferably, the sample inlet chamber 2 may also be provided with a heating module (not shown in the figures), such as a conventional electric heater or the like, to control the temperature of the inlet gas flow. In addition, the cylindrical shell of the sample inlet bin 2 or the cover plates at the two ends of the roller 1 can be made of transparent materials, such as transparent resin, glass and the like, and a simulated solar light source is additionally arranged outside the device to simulate the atmospheric illumination condition. It can be understood that the simulated solar light source can also be arranged inside the roller 1, and thus, the illumination effect can be realized without adopting transparent materials.
Temperature and humidity probe 7 sets up on appearance storehouse 3 for the inside humiture of monitoring devices, of course, temperature and humidity probe 7 also can set up on cylinder 1. Aerosol detection device 8 and air cleaner 9 then link to each other with the storehouse of drawing a sample 3 through the pipeline respectively, and aerosol detection device 8 is commercially available, including sample thief, particle counter etc. for collection, detection etc. of aerosol sample, and air cleaner 9 can select the high efficiency particle air cleaner, filtration when mainly used device interior exhaust emission.
During the experiment, the whole set of device can be placed in an experimental biological safety cabinet, and the following description is provided by a specific embodiment:
1) and adjusting the proportion of the pure dry air and the nitrogen flow and the heating module of the sample injection bin to maintain the temperature and the humidity of the air at a set value. Light or dark conditions can be preset by replacing the roller cover plate.
2) A viral suspension of a certain titer is placed in an aerosol generator and the generated aerosol is passed into a roller. The flow rate of the aerosol generator is 3.9L/min, and the generation time is 20 min. The inlet and outlet valves of each pipe were closed, and the drum was set to rotate at 2.5rpm, mixing for 1 min.
3) Control group: and opening the inlet and outlet valves. Collecting aerosol samples to a gelatin filter membrane through a biological aerosol sampler, wherein the sampling flow is 5L/min, and the sampling time is 5 min; in addition, the particle number concentration was also measured by a particle counter.
4) Control group: and closing the sample outlet bin valve. The exposure experiment was performed on the virus aerosol by passing a concentration of oxidant (e.g., NOx, O3, etc.). The sampling bin valve is closed and the drum is rotated for a period of time (e.g., 60 min). Opening the inlet and outlet valves, collecting aerosol sample on 80-mm gel filter membrane, sampling flow at 5L/min, and collecting for 5 min.
5) The above processes are repeated, and the exposure control group of the virus aerosol can be set with different temperature, humidity, oxidant and illumination conditions.
The above detailed description is specific to possible embodiments of the present invention, and the embodiments are not intended to limit the scope of the present invention, and all equivalent implementations or modifications that do not depart from the scope of the present invention should be included within the scope of the present invention.
Claims (4)
1. An apparatus for studying the evolution of a viral aerosol in the atmosphere, characterized by: the system comprises an aerosol introduction module, an aerosol simulated evolution module and an aerosol measurement module;
the aerosol introducing module comprises a sample introduction cabin, an aerosol generator, a nitrogen source and a simulation air source; the aerosol simulated evolution module comprises a roller and a driving device for driving the roller to rotate; the aerosol measurement module comprises a sample outlet bin, a temperature and humidity probe, an aerosol detection device and an air filter;
the sample feeding bin and the sample discharging bin are horizontally fixed on the bracket at intervals, and the roller is rotatably arranged between the sample feeding bin and the sample discharging bin and is communicated with the sample feeding bin and the sample discharging bin; the simulation air source is connected with the sample injection bin, the nitrogen source is divided into two paths, one path is directly connected with the sample injection bin, and the other path is connected with the sample injection bin through the aerosol generator; the temperature and humidity probe is arranged on the sample outlet bin, and the aerosol detection device and the air filter are respectively connected with the sample outlet bin.
2. The apparatus of claim 1, wherein the apparatus is further configured to study the evolution of viral aerosols in the atmosphere: and the sample feeding bin is provided with a heating module.
3. The apparatus of claim 1, wherein the apparatus is further configured to study the evolution of viral aerosols in the atmosphere: the sample feeding bin or the cover plate at the end part of the roller is made of transparent materials, and a simulated solar light source is arranged outside the device.
4. The apparatus of claim 1, wherein the apparatus is further configured to study the evolution of viral aerosols in the atmosphere: the inner wall of the roller is provided with a Teflon coating.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023043789.9U CN214503260U (en) | 2020-12-15 | 2020-12-15 | Device for researching evolution of virus aerosol in atmosphere |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023043789.9U CN214503260U (en) | 2020-12-15 | 2020-12-15 | Device for researching evolution of virus aerosol in atmosphere |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214503260U true CN214503260U (en) | 2021-10-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202023043789.9U Expired - Fee Related CN214503260U (en) | 2020-12-15 | 2020-12-15 | Device for researching evolution of virus aerosol in atmosphere |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214503260U (en) |
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2020
- 2020-12-15 CN CN202023043789.9U patent/CN214503260U/en not_active Expired - Fee Related
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
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Granted publication date: 20211026 |