CN112857924B - Small and medium-sized experimental animal exhaled aerosol collection system - Google Patents
Small and medium-sized experimental animal exhaled aerosol collection system Download PDFInfo
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- CN112857924B CN112857924B CN202110383657.0A CN202110383657A CN112857924B CN 112857924 B CN112857924 B CN 112857924B CN 202110383657 A CN202110383657 A CN 202110383657A CN 112857924 B CN112857924 B CN 112857924B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/22—Devices for withdrawing samples in the gaseous state
- G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
- G01N1/2205—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling with filters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
- A61L2/10—Ultra-violet radiation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/22—Devices for withdrawing samples in the gaseous state
- G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
- G01N2001/222—Other features
- G01N2001/2223—Other features aerosol sampling devices
Abstract
The invention discloses a middle and small-sized experimental animal exhaled aerosol collecting device, which relates to the technical field of gas sample collection and comprises a collecting device body, wherein the collecting device body comprises an animal fixing system, a sampling system, a monitoring system and a controller; the animal fixing system comprises a bin body, the bin body is arranged on a support frame, a bin cover is arranged at the top of the bin body, and an animal fixing device is arranged in the bin body and used for fixing small and medium-sized experimental animals; the bottom of the bin body is provided with a sampling port, a pipeline connector is mounted on the sampling port, an air inlet of the pipeline connector is connected with the animal fixing device, the sampling system is connected with an air outlet of the pipeline connector, and the bin body is also connected with the monitoring system; the sampling system and the monitoring system are both connected with the controller. The invention can safely and quickly collect aerosol samples exhaled by small and medium-sized experimental animals.
Description
Technical Field
The invention relates to the technical field of gas sample collection, in particular to a device for collecting exhaled aerosol of small and medium-sized experimental animals.
Background
Aerosols (Aerosol) are stable dispersions of particles and air in which solid or liquid particles are suspended for extended periods of time in the air. If the particles contain microorganisms, a microbial aerosol is formed. Depending on the type of microorganism, they can be classified into viral aerosols (viraerosol), bacterial aerosols (bacteriolaerosol), and fungal aerosols (fungaeerosol). The particle size range that a person can call in is 0.5-5 μm. Since these particles are themselves small enough, the settling velocity in a gaseous medium is low, they can be suspended in air for long periods of time, and they can drift away with the wind.
The wide spread and increased concentration of the microbial aerosol can cause atmospheric environmental pollution, so that the probability of outbreak of certain infectious diseases is increased, and the microbial aerosol poses serious threats to human health, normal life and normal production of animal husbandry.
For example, influenza virus is an important respiratory transmission pathogen, has wide host range, high mutation speed and strong transmission capability, even causes pandemics in the world for many times, and brings great harm to human health and livestock and poultry breeding industry. The guinea pig is one of important animal models for evaluating the transmission capability of influenza viruses among mammals, and the understanding of the aerosol detoxification rule of the guinea pig infected with the influenza viruses has important reference significance for scientifically judging the transmission capability and comprehensive prevention and control of the influenza viruses. However, no experimental device capable of monitoring and collecting aerosol particles exhaled by small and medium-sized experimental animals such as guinea pigs in real time exists at present.
Therefore, it is needed to provide a device for collecting exhaled breath sols from small and medium-sized experimental animals to solve the above problems in the prior art.
Disclosure of Invention
The invention aims to provide a device for collecting exhaled aerosol of small and medium-sized experimental animals, which is used for solving the problems in the prior art and safely and quickly collecting aerosol samples exhaled by the small and medium-sized experimental animals.
In order to achieve the purpose, the invention provides the following scheme:
the invention provides a middle and small-sized experimental animal exhaled aerosol collecting device which comprises a collecting device body, wherein the collecting device body comprises an animal fixing system, a sampling system, a monitoring system and a controller; the animal fixing system comprises a bin body, the bin body is arranged on a support frame, a bin cover is arranged at the top of the bin body, and an animal fixing device is arranged in the bin body and used for fixing small and medium-sized experimental animals; the bottom of the bin body is provided with a sampling port, a pipeline connector is mounted on the sampling port, an air inlet of the pipeline connector is connected with the animal fixing device, the sampling system is connected with an air outlet of the pipeline connector, and the bin body is also connected with the monitoring system; the sampling system and the monitoring system are both connected with the controller.
Preferably, the animal fixing device is provided with a plurality of animal fixing devices which are uniformly distributed around the sampling port along an annular shape.
Preferably, a plurality of air inlets are arranged on the pipeline connecting head, the number of the air inlets is equal to the number of the animal fixing devices correspondingly, and each air inlet is connected with one animal fixing device; the gas outlet of pipeline connector is provided with two, including first gas outlet and second gas outlet, first gas outlet with sampling system connects.
Preferably, the monitoring system comprises a particle size spectrometer, and the particle size spectrometer is connected with the second air outlet;
the monitoring system further comprises a pressure sensor, a humidity sensor, a temperature sensor and an oxygen concentration sensor, wherein the pressure sensor, the humidity sensor, the temperature sensor and the oxygen concentration sensor are all installed in the bin body.
Preferably, the sampling system comprises a fractional sampler, the fractional sampler is connected with the first gas outlet, and the fractional sampler is further connected with a sampling pump.
Preferably, the bin body is further provided with two air filters, the two air filters comprise a first air filter and a second air filter, and the first air filter and the second air filter are symmetrically arranged on two sides of the top of the bin body respectively.
Preferably, a lighting lamp is further arranged in the bin body;
still be provided with degassing unit in the storehouse body, degassing unit adopts ultraviolet lamp.
Preferably, the front surface of the bin body is made of transparent materials, and the front surface of the bin body is also provided with an operation window; the operation window is provided with a detachable operation sleeve, one end of the operation sleeve is provided with a sleeve hole and is arranged on the sampling window, and the other end of the operation sleeve is provided with a glove which extends into the bin body.
Preferably, the animal fixing device comprises a fixing bottle body, the tail end of the fixing bottle body is provided with a fixing cover, and the front end of the fixing bottle body is provided with an opening for connecting with an air inlet of the pipeline connector; a push plate is further arranged in the fixing bottle body and used for fixing small and medium-sized experimental animals, and the push plate is connected with a push rod which penetrates through the fixing cover; the fixed cover is also provided with a vent hole, and the vent hole is provided with a filter screen.
Preferably, the fixed bottle body is arranged on a fixed support, and the fixed support comprises a base, a support rod, a rotary sleeve and an arc-shaped mounting plate; the bottom of the supporting rod is connected with the base, the top of the supporting rod is rotatably provided with the rotating sleeve, and the arc-shaped mounting plate is arranged at the top of the rotating sleeve and used for supporting the fixed bottle body; the bottom of the arc-shaped mounting plate is rotatably connected with the rotating sleeve through a pin shaft.
Compared with the prior art, the invention has the following technical effects:
the invention fills the technical blank that the particle size spectrum of the animal exhaled breath aerosol particles cannot be accurately analyzed in real time in the prior art, can effectively reduce the influence of environmental aerosol particles on experimental results, can analyze the concentration and the particle size distribution characteristics of total particulate matters in the exhaled breath of guinea pigs, can also carry out microorganism particle size grading sampling, analyzes the concentration and the particle size distribution characteristics of microorganism aerosol, and is favorable for further and systematically researching the popularity and the propagation mechanism of microorganisms.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
FIG. 1 is a schematic structural diagram of a device for collecting exhaled aerosol from a small and medium-sized laboratory animal according to the present invention;
FIG. 2 is a top view of a device for collecting exhaled aerosol from a small or medium-sized laboratory animal according to the present invention;
FIG. 3 is a schematic view of the construction of the animal holding device of the present invention;
FIG. 4 is a schematic structural view of the fixing cover of the present invention;
FIG. 5 is a schematic structural view of a fixing support according to the present invention;
wherein: 1-cabin body, 2-first air filter, 3-second air filter, 4-animal fixing device, 41-fixed bottle body, 42-push plate, 43-push rod, 44-fixed cover, 45-fixed clamp, 46-vent hole, 5-sampling port, 6-ultraviolet lamp, 7-support frame, 8-fixed support, 81-base, 82-support rod, 83-arc-shaped mounting plate, 84-rotary sleeve, 85-pin shaft, 9-left operation window, 10-right operation window, 11-pipeline connector, 12-lighting lamp, 13-particle size spectrometer, 14-fractional sampler, and 15-sampling pump.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without inventive effort based on the embodiments of the present invention, are within the scope of the present invention.
The invention aims to provide a device for collecting exhaled aerosol of small and medium-sized experimental animals, which is used for solving the problems in the prior art and safely and quickly collecting aerosol samples exhaled by the small and medium-sized experimental animals.
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in further detail below.
Example one
As shown in fig. 1-5: the embodiment provides a device for collecting exhaled aerosol of small and medium-sized experimental animals, which comprises a collecting device body, wherein the collecting device body comprises an animal fixing system, a sampling system, a monitoring system and a controller; the animal fixing system comprises a bin body 1, the bin body 1 is preferably a cuboid bin body with the length of 1m, the width of 0.8m and the height of 0.6m, and the size of the bin body can be adjusted according to specific working requirements; the animal experiment device comprises a bin body 1, a bin cover, an animal fixing device 4 and a control device, wherein the bin body 1 is arranged on a support frame 7, the top of the bin body 1 is provided with the bin cover, and the animal fixing device 4 is arranged in the bin body 1 and used for fixing small and medium-sized experimental animals; a sampling port 5 is arranged at the right center of the bottom of the bin body 1, a pipeline connector 11 is arranged on the sampling port 5, an air inlet of the pipeline connector 11 is connected with the animal fixing device 4, a sampling system is connected with an air outlet of the pipeline connector 11, and the bin body 1 is also connected with a monitoring system; the sampling system and the monitoring system are both connected with the controller.
In the embodiment, a plurality of animal fixing devices 4 are arranged, a plurality of animal fixing devices 4 are uniformly distributed around the sampling port 5 along an annular direction, and a plurality of animal fixing devices 4 are arranged, so that a plurality of small and medium-sized experimental animals can be tested at the same time, and the experimental efficiency is improved; in this embodiment, four animal fixing devices 4 are preferably provided, and the small and medium-sized experimental animals may be guinea pigs or the like.
In this embodiment, the pipeline connector 11 is provided with a plurality of air inlets, the number of the air inlets is equal to the number of the animal fixing devices 4, and each air inlet is connected with one animal fixing device 4; two air outlets of the pipeline connector 11 are arranged, and comprise a first air outlet and a second air outlet, and the first air outlet is connected with the sampling system; wherein, all be provided with control flap on air inlet and the gas outlet for control its switch.
In this embodiment, the monitoring system includes a particle size spectrometer 13 of TSI3321 type, the particle size spectrometer 13 is connected to the second air outlet, the particle size spectrometer 13 can monitor the aerodynamic particle size of aerosol particles in the animal fixing system in real time or at different time periods, and give the distribution of aerosol quantity concentration, surface area concentration, volume concentration and mass concentration along with the particle size; the controller is connected with the particle size spectrometer 13, controls the sampling frequency and the sampling time of the particle size spectrometer 13, and reads analysis data.
Further, monitoring system still includes pressure sensor, humidity transducer, temperature sensor and oxygen concentration sensor, and pressure sensor, humidity transducer, temperature sensor and oxygen concentration sensor all install in the storehouse internal, can carry out real-time supervision to the gaseous environment of the storehouse body.
In this embodiment, the sampling system includes a graded sampler 14, the graded sampler 14 is connected to the first gas outlet, and the graded sampler 14 is further connected to a sampling pump 15; the graded sampler 14 is an Anderson six-grade sampler and is used for dividing aerosol particles exhaled by the guinea pig into 6 different particle size intervals for collection so as to analyze the characteristics of the microbial aerosol particles exhaled by the guinea pig; the sampling pump 15 is connected with the Anderson six-stage sampler through a plastic hose, provides a sampling power source (28.3L/min) for the Anderson six-stage sampler 14 and controls sampling time.
In this embodiment, the silo body 1 is further provided with two air filters, the two air filters include a first air filter 2 and a second air filter 3, and the first air filter 2 and the second air filter 3 are respectively symmetrically arranged on two sides of the top of the silo body 1; wherein, air cleaner's kind is selected from prior art according to concrete work needs, sets up two air cleaner and can filters the air microorganism, finally carries sterile air in storehouse body 1.
In this embodiment, the cabin 1 is further provided with an illuminating lamp 12 for illuminating; still be provided with degassing unit in the storehouse body 1, degassing unit adopts ultraviolet lamp 6, can disinfect to the air in the storehouse body 1, reduces the influence of the aerosol that exists in the external environment to the experimental result.
In this embodiment, the front surface of the bin body 1 is made of a transparent material (acrylic plate or glass plate), or the whole bin body 1 is made of a transparent material, and the front surface of the bin body 1 is further provided with two operation windows, including a left operation window 9 and a right operation window 10; the operation window is provided with a detachable operation sleeve, one end of the operation sleeve is provided with a sleeve hole and is arranged on the sampling window, and the other end of the operation sleeve is provided with a glove and extends into the bin body 1.
In this embodiment, the animal fixing device 4 includes a fixing bottle 41, a fixing cover 44 is disposed at the tail end of the fixing bottle 41, and an opening is disposed at the front end for connecting with the air inlet of the pipeline connector 11; the fixed bottle body 41 is also internally provided with a push plate 42, the small and medium-sized laboratory animals are positioned between the opening and the push plate 42, the mouth-nose part of the small and medium-sized laboratory animals is positioned at the opening, the push plate 42 is used for fixing the small and medium-sized laboratory animals, and the laboratory animals with different sizes can be fixed by adjusting the position of the push plate 42; the push plate 42 is connected with a push rod 43, and the push rod 43 penetrates through the fixed cover 44; the fixing cover 44 is further provided with a vent hole 46 for providing sufficient air for the experimental animal in the fixing bottle body 41, and the vent hole 46 is provided with a filter screen. Wherein, the fixing clips 45 are further disposed on the outer walls of the two sides of the fixing bottle 41 for fixing the fixing cover 44.
In this embodiment, the fixed bottle 41 is mounted on the fixed support 8, and the fixed support 8 includes a base 81, a support rod 82, a rotating sleeve 84 and an arc-shaped mounting plate 83; the bottom of the supporting rod 82 is connected with the base 81, the top of the supporting rod is rotatably provided with a rotating sleeve 84, and the rotating sleeve 84 axially rotates along the supporting rod 82; the arc-shaped mounting plate 83 is mounted at the top of the rotating sleeve 84 and used for supporting the fixed bottle body 41, the rotating sleeve 84 can drive the arc-shaped mounting plate 83 to rotate, the whole fixed bottle body 41 is further driven to rotate, and direction adjustment is achieved; the bottom of the arc-shaped mounting plate 83 is rotatably connected with the rotating sleeve 84 through a pin 85, so that the inclination angle adjustment of the fixed bottle body 41 can be realized. Still be provided with fixing device such as magic subsides on the arc mounting panel 83 for fix fixed bottle 41, still be provided with the flexible material layer on the inner wall of arc mounting panel 83, be used for effectively protecting fixed bottle 41.
In this embodiment, the silo body 1 is further connected with an exhaust gas treatment system, and the exhaust gas treatment system comprises an air processor, an exhaust gas flow controller, a control valve and a vacuum pump; specifically, an air outlet on the bin body 1 is connected with an air processor through an air outlet pipe, and residual waste gas in the bin body 1 can be purified and then discharged through the air processor, so that the influence on the environment is reduced; the gas outlet pipe can be provided with a waste gas flow controller and a control valve for control, and is connected with a vacuum pump for providing power.
The working flow in this embodiment is as follows:
when the device works, the front panel of the cabin body 1 is opened, the anesthetized guinea pig to be tested is placed in the cabin body 1, the front panel is closed, and the guinea pig is fixed in the fixed bottle body 41 through the operating gloves of the operating window. After the smell of the guinea pig is stable, firstly connecting a particle size spectrometer 13 to a second air outlet of the pipeline connector 11, and continuously monitoring to obtain aerosol particle size spectrum characteristics in the exhaled gas of the guinea pig; then, connecting an Anderson six-level sampler to a first air outlet, continuously sampling for 30 minutes, and analyzing the concentration and the particle size distribution of the microorganism aerosol exhaled by the guinea pig by measuring the content of the microorganism in the sampled sample; when continuously monitoring or continuously sampling, negative pressure is generated in the experimental cabin body 1, air microorganisms are filtered through the air filter, and finally sterile air is conveyed into the cabin body 1, and directional airflow from the top to the bottom and from the periphery to the center is formed.
During the experiment, the behavior and mental state of the tested animal in the bin body 1 are observed through the transparent panel on the front side of the bin body 1, and the in-bin test operation is carried out through the operation window; the illuminating lamp 12 and the ultraviolet lamp provide required illumination and disinfection in the warehouse for the experimental animals. After the experiment is completed, the waste gas is discharged after being treated by the waste gas treatment system.
The principle and the implementation mode of the present invention are explained by applying specific examples in the present specification, and the above descriptions of the examples are only used to help understanding the method and the core idea of the present invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, the specific embodiments and the application range may be changed. In view of the above, the present disclosure should not be construed as limiting the invention.
Claims (7)
1. The utility model provides a middle-size and small-size experimental animals exhale aerosol collection system which characterized in that: the device comprises a collecting device body, wherein the collecting device body comprises an animal fixing system, a sampling system, a monitoring system and a controller; the animal fixing system comprises a bin body, the bin body is arranged on a support frame, a bin cover is arranged at the top of the bin body, an animal fixing device is arranged in the bin body and used for fixing small and medium-sized experimental animals, and the bin body is also connected with the monitoring system; the bottom of the bin body is provided with a sampling port, a pipeline connector is mounted on the sampling port, an air inlet of the pipeline connector is connected with the animal fixing device, the animal fixing device comprises a fixing bottle body, a fixing cover is arranged at the tail end of the fixing bottle body, and an opening is formed in the front end of the fixing bottle body and used for being connected with the air inlet of the pipeline connector; a push plate is further arranged in the fixing bottle body and used for fixing small and medium-sized experimental animals, and the push plate is connected with a push rod which penetrates through the fixing cover; the fixed cover is also provided with a vent hole, and a filter screen is arranged on the vent hole; a plurality of animal fixing devices are arranged and are uniformly distributed along the ring shape around the sampling port;
the two gas outlets of the pipeline connector comprise a first gas outlet and a second gas outlet, the first gas outlet is connected with the sampling system, the sampling system comprises a graded sampler, the graded sampler is connected with the first gas outlet, the graded sampler is also connected with a sampling pump, and the graded sampler can divide aerosol particles exhaled by the guinea pig into different particle size sections for collection so as to analyze the characteristics of the microbial aerosol particles exhaled by the guinea pig; the monitoring system comprises a particle size spectrometer, the particle size spectrometer is connected with the second air outlet, the particle size spectrometer can monitor the aerodynamic particle size of aerosol particles in the animal fixing device in real time or at different time periods, and the distribution conditions of the quantity concentration, the surface area concentration, the volume concentration and the mass concentration of the aerosol along with the particle size are given; the sampling system and the monitoring system are both connected with the controller;
the bin body is also connected with an exhaust gas treatment system, and the exhaust gas treatment system comprises an air processor, an exhaust gas flow controller, a control valve and a vacuum pump; the air outlet on the bin body is connected with the air processor through an air outlet pipe, the exhaust gas flow controller and the control valve are arranged on the air outlet pipe, and the exhaust gas flow controller and the control valve are connected with the vacuum pump.
2. The device for collecting exhaled aerosol of small and medium-sized laboratory animals according to claim 1, wherein: the pipeline connector is provided with a plurality of air inlets, the number of the air inlets corresponds to the number of the animal fixing devices, and each air inlet is connected with one animal fixing device.
3. The device for collecting exhaled aerosol of small and medium-sized laboratory animals according to claim 2, wherein: the monitoring system further comprises a pressure sensor, a humidity sensor, a temperature sensor and an oxygen concentration sensor, wherein the pressure sensor, the humidity sensor, the temperature sensor and the oxygen concentration sensor are all installed in the bin body.
4. The device for collecting exhaled aerosol of small and medium-sized laboratory animals according to claim 1, wherein: the bin body is further provided with two air filters, each air filter comprises a first air filter and a second air filter, and the first air filters and the second air filters are symmetrically arranged on two sides of the top of the bin body respectively.
5. The device for collecting exhaled aerosol of small and medium-sized laboratory animals according to claim 1, wherein: the bin body is also internally provided with a lighting lamp;
still be provided with degassing unit in the storehouse body, degassing unit adopts ultraviolet lamp.
6. The device for collecting exhaled aerosol of small and medium-sized laboratory animals according to claim 1, wherein: the front side of the bin body is made of transparent materials, and the front side of the bin body is also provided with an operation window; the detachable operation oversleeve is installed on the operation window, one end of the operation oversleeve is provided with an oversleeve hole and is installed on the operation window, and the other end of the operation oversleeve is provided with a glove which extends into the cabin body.
7. The device for collecting exhaled aerosol of small and medium-sized laboratory animals according to claim 1, wherein: the fixed bottle body is arranged on a fixed support, and the fixed support comprises a base, a support rod, a rotary sleeve and an arc-shaped mounting plate; the bottom of the supporting rod is connected with the base, the top of the supporting rod is rotatably provided with the rotating sleeve, and the arc-shaped mounting plate is arranged at the top of the rotating sleeve and used for supporting the fixed bottle body; the bottom of the arc-shaped mounting plate is rotatably connected with the rotating sleeve through a pin shaft.
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| CN202110383657.0A CN112857924B (en) | 2021-04-09 | 2021-04-09 | Small and medium-sized experimental animal exhaled aerosol collection system |
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| CN202110383657.0A CN112857924B (en) | 2021-04-09 | 2021-04-09 | Small and medium-sized experimental animal exhaled aerosol collection system |
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| US4520808A (en) * | 1983-03-10 | 1985-06-04 | Stauffer Chemical Company | Inhalation exposure apparatus |
| CN2865604Y (en) * | 2006-02-17 | 2007-02-07 | 范维林 | Solid phase dust-like dynamic inhalation contamination experimental device |
| CA2701352A1 (en) * | 2007-10-02 | 2009-04-09 | Ann-Charlotte Almstrand | Collection and measurement of exhaled particles |
| KR101348825B1 (en) * | 2012-07-24 | 2014-01-08 | 한국화학연구원 | Exposure chamber for testing inhalation toxicity of nanopaticles for primates |
| CN103645070B (en) * | 2013-12-10 | 2015-12-30 | 天津开发区合普工贸有限公司 | A kind of toy respiration test is used radial without reflux gas sampling apparatus |
| CN203965418U (en) * | 2014-07-08 | 2014-11-26 | 浙江大学 | The greenhouse gases pick-up unit that ruminant is breathed out |
| CN204142464U (en) * | 2014-09-02 | 2015-02-04 | 中国人民解放军军事医学科学院军事兽医研究所 | A kind of can the aerosol transmission pilot system of simulating natural environment |
| CN206540732U (en) * | 2017-01-25 | 2017-10-03 | 北京师范大学 | Animal expiration collection device |
| CN207913734U (en) * | 2017-08-19 | 2018-09-28 | 中国人民解放军军事医学科学院军事兽医研究所 | A kind of pathogenic microorganism aerosol research system |
| CN109374359A (en) * | 2018-09-17 | 2019-02-22 | 北京师范大学 | Animal expiration collection device |
| CN209435980U (en) * | 2018-10-10 | 2019-09-27 | 中国人民解放军军事科学院军事医学研究院 | Big animal pathogen air borne experimental provision in high-grade biological safety protection formula |
| CN209802930U (en) * | 2019-03-06 | 2019-12-17 | 南京农业大学 | animal feeding test device under dust exposes |
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| CN211652770U (en) * | 2019-12-24 | 2020-10-09 | 北京市机械工业局技术开发研究所 | Wearable monitoring device for greenhouse gas exhaled by ruminant |
| CN211793596U (en) * | 2020-03-05 | 2020-10-30 | 南开大学 | Laboratory is with mouse particulate matter expose cabin device |
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