CN214496265U - 24-hole consumable for nucleic acid extraction instrument - Google Patents

Abstract

The utility model relates to an experiment consumptive material technical field, in particular to 24 hole consumptive materials for nucleic acid extraction appearance, include the deep hole board with be used for installing in apron on the deep hole board, be provided with the magnetic sleeve head on the apron, 24 deep holes have been seted up on the deep hole board, the groove of stepping down has been seted up on the deep hole board, the groove of stepping down with the deep hole is seted up in the both sides of deep hole board. The device has the advantage of convenient use.

Description

24-hole consumable for nucleic acid extraction instrument

Technical Field

The application relates to the technical field of experimental consumables, in particular to a 24-hole consumable for a nucleic acid extraction instrument.

Background

Nucleic acid is one of the most basic substances of life, and is widely present in all animal and plant cells and microorganisms. Along with the popularization of gene detection, personalized drug delivery, prenatal diagnosis and the like, high-throughput and automatic nucleic acid extraction methods are pursued in various fields of the biological industry, and because the magnetic bead method is used for extracting nucleic acid, automatic extraction can be realized, large-scale operation can be carried out, the operation is simple, the time consumption is short, and the magnetic bead method is more and more emphasized in extracting nucleic acid.

In the existing nucleic acid extraction device, a hole consumable is placed on a heating module, and then the bottom of the hole consumable is heated by the heating module, so that the nucleic acid in the hole consumable is heated; or, in order to improve work efficiency, shorten heating time, increased the degree of depth in heating module heated hole to can heat the lateral wall of hole consumptive material, but, can only insert single body to the heated hole of heating module in, practical inconvenient.

SUMMERY OF THE UTILITY MODEL

To the not enough that prior art exists, the purpose of this application is to provide a 24 hole consumptive materials for nucleic acid extraction appearance, and the device has convenient to use's advantage.

The technical purpose of the application is realized by the following technical scheme:

the utility model provides a 24 hole consumptive materials for nucleic acid extraction appearance, includes the deep hole board with be used for installing in apron on the deep hole board, be provided with the magnetic sleeve head on the apron, 24 deep holes have been seted up on the deep hole board, the groove of stepping down has been seted up on the deep hole board, the groove of stepping down with the deep hole is seted up in the both sides of deep hole board.

Through adopting above-mentioned technical scheme, having seted up the groove of stepping down around the deep orifice plate, directly pegging graft the deep orifice plate in the heating module heating hole, at this moment, the heating module can heat the outer peripheral face of the body of deep orifice plate, and then can cross the heating time who shortens the nucleic acid extraction in-process. Therefore, the application has the advantage of convenience in use.

Preferably, the height of the abdicating groove is 2.5-6 cm.

Preferably, the receding groove is provided with a plurality of, and the bottom of deep hole is around there being four receding grooves.

Through adopting above-mentioned technical scheme, can insert the projection of heating module to the inslot of stepping down to can conveniently heat the nucleic acid in the deep hole to the heating module.

Preferably, the peripheral surface of the deep hole plate is provided with an annular frame, the deep hole and the abdicating groove are positioned in the ring of the annular frame, the upper surface of the annular frame is positioned in the middle of the peripheral surface of the deep hole plate, and the lower surface of the annular frame is lower than the lower surface of the deep hole plate.

Through adopting above-mentioned technical scheme, the support to the deep hole board can be realized to the annular frame to can guarantee the stability of deep hole board.

Preferably, the annular frame is fixedly connected to the deep hole plate.

Through adopting above-mentioned technical scheme, with annular frame and deep hole board fixed connection, this deep hole board is disposable deep hole board, facilitates the use.

Preferably, the deep hole plate and the annular frame are detachably connected.

Through adopting above-mentioned technical scheme, can dismantle the deep-hole board and connect on the annular frame, only need change the deep-hole board to can save material.

Preferably, the upper surface of the annular frame is provided with two fixing grooves which are oppositely arranged, the peripheral surface of the deep hole plate is provided with two limiting blocks which are oppositely arranged, when the deep hole plate is inserted into the annular frame, the limiting blocks are arranged in the fixing grooves, and the limiting blocks correspond to the fixing grooves one to one.

Through adopting above-mentioned technical scheme, peg graft the stopper in the fixed slot to can install the deep hole board on the annular frame.

Preferably, one side of the limiting block, which is far away from the deep hole opening, is provided with an insertion block, the insertion block is located at one end of the limiting block, which is far away from the deep hole plate, the annular frame is provided with an insertion groove in the bottom wall of the fixing groove, and when the deep hole plate is inserted in the annular frame, the insertion block is installed in the insertion groove.

By adopting the technical scheme, the inserting block is inserted into the inserting groove, so that the fixing capacity of the deep hole plate can be further improved.

Preferably, the deep hole plate comprises a plurality of rows of sub-plates, and the two limit blocks are respectively positioned on two sides of the sub-plates.

When 24 hole consumptive materials are used to the sample quantity too few, the nucleic acid sample can cause the pollution to other deep holes to lead to the waste of this consumptive material, through adopting above-mentioned technical scheme, the setting of multirow daughter board can be adjusted according to the quantity of sample, reduces the waste of resource.

In summary, the present application has the following beneficial effects: offer the groove of stepping down around with the deep hole board, directly peg graft the deep hole board in the heating module's heating hole, at this moment, the heating module can heat the outer peripheral face of the body of deep hole board, and then can cross the heating time who shortens the nucleic acid extraction in-process. Therefore, the application has the advantage of convenience in use.

Drawings

FIG. 1 is an exploded view of the entire structure of example 1 of the present application;

FIG. 2 is a side view of embodiment 1 of the present application;

FIG. 3 is a cross-sectional view taken along line A-A of FIG. 2;

FIG. 4 is a side view of the present application in example 2;

FIG. 5 is a cross-sectional view taken along line B-B of FIG. 4;

fig. 6 is a partially enlarged schematic view of a portion C in fig. 5.

In the figure: 1. a deep hole plate; 11. a yielding groove; 12. a limiting block; 121. an insertion block; 13. deep holes; 2. a cover plate; 21. a magnetic sleeve head; 22. a limiting plate; 23. a bump; 3. a heating module; 31. heating plates; 311. mounting grooves; 32. mounting blocks; 321. heating the hole; 33. a convex column; 4. an annular frame; 41. fixing grooves; 42. inserting grooves; 43. a groove; 5. a daughter board; 6. and a sub-cover plate.

Detailed Description

The present application is described in further detail below with reference to the attached drawings.

Example 1: referring to FIG. 1, the consumable 24 wells for nucleic acid isolation instrument disclosed in the present application comprises a deep well plate 1 mounted on a heating module 3 and a cover plate 2 mounted on the deep well plate 1.

Heating module 3 includes hot plate 31, installation piece 32 and a plurality of projection 33, and mounting groove 311 has been seted up to the upper surface of hot plate 31, and installation piece 32 sets firmly in the center of mounting groove 311, and a plurality of heated holes 321 have been seted up to the upper surface of installation piece 32, and this embodiment is provided with a heated hole 321, and heated hole 321 is the setting of six rows of four. The convex column 33 is fixedly arranged on the upper surface of the mounting block 32, the convex column 33 is located on the outer side of the heating hole 321, the heating plate 31 and the convex column 33 are both made of heat-conducting metal materials, the periphery of each heating hole 321 corresponds to the four convex columns 33, one side of each convex column 33 facing the heating hole 321 is in arc surface arrangement, and the opening of the arc surface of each convex column 33 faces the direction of the central line of the heating hole 321. When the convex pillar 33 is located at the corner of the heating plate 31, the convex pillar 33 is only close to one heating hole 321; when the convex column 33 is located at the edge of the mounting block 32, the convex column 33 is located in two adjacent heating holes 321, and when the convex column 33 is located inside the mounting block 32, the convex column 33 is located at the center of the four heating holes 321, and the convex column 33 is located at the center of the four heating holes 321. The heating holes 321 are arranged in a cone shape, the depth of the heating holes 321 is 0.5-1.5cm, the height of the convex columns 33 is 2.5-4cm, in the embodiment, the depth of the heating holes 321 is 1cm, and the height of the convex columns 33 is 3 cm.

Referring to fig. 2 and 3, the upper surface of the deep hole plate 1 is provided with 24 deep holes 13, the 24 deep holes 13 are arranged in six rows and six columns, the lower surface of the deep hole plate 1 is provided with a plurality of abdicating grooves 11, the bottom of the deep hole 13 surrounds the four abdicating grooves 11, the height of the abdicating grooves 11 is 2.5-6cm, in this embodiment, the height of the abdicating grooves 11 is 4cm, the abdicating grooves 11 and the deep holes 13 are arranged on the upper and lower sides of the deep hole plate 1, through the abdicating grooves 11, the bottom of the deep hole plate 1 on the outer peripheral surface of the deep hole 13 is arranged in a cone shape, the bottoms of the 24 deep holes 13 independently form 24 tubes, when the bottom of the deep hole plate 1 is inserted into the heating hole 321, the convex column 33 is inserted into the abdicating grooves 11, the arc surface of the convex column 33 abuts against the outer surface of the deep hole plate 1, the convex column 33 heats the tubes of the deep hole plate 1, and the convex column 33 heats the four tubes of the deep hole plate 1 simultaneously, so that the space for installing the boss 33 can be saved.

The outer peripheral face of deep hole board 1 has set firmly annular frame 4, deep hole 13 and the groove 11 of stepping down all are located annular frame 4, and the upper surface of annular frame 4 is located the middle part of deep hole board 1 outer peripheral face, and the lower surface of annular frame 4 is less than the lower surface of deep hole board 1, when pegging graft the body of deep hole board 1 in heating hole 321, and annular frame 4 pegs graft in mounting groove 311 to install deep hole board 1 on heating module 3.

The lower surface of the cover plate 2 is provided with a magnetic sleeve head 21, and when the cover plate 2 is covered on the deep hole plate 1, the magnetic sleeve head 21 is inserted in the deep hole 13; the lower surface of apron 2 has set firmly two limiting plates 22, and two limiting plates 22 are located the both ends of apron 2 respectively, and when installing apron 2 on deep hole board 1, two limiting plates 22 butt in deep hole board 1's both sides to can cover apron 2 on deep hole board 1. The upper surface of apron 2 sets firmly lug 23, and the lower surface of annular frame 4 is seted up flutedly 43, when storing this deep hole board 1, pegs graft in the recess 43 that is located the deep hole board 1 of upper end with lug 23 that is located the deep hole board 1 of lower extreme to can pile together deep hole board 1, and then can save storage space.

The specific working principle in this application: in the process of nucleic acid extraction, place deep hole board 1 on heating module 3, the body of deep hole board 1 is pegged graft in heating hole 321, and simultaneously, projection 33 is pegged graft in the groove of stepping down 11, and projection 33 can heat the body outer peripheral face of deep hole board 1, can increase the heated area of the body of deep hole board 1 to reduce the heat time to the sample, and then improve work efficiency.

Example 2: as shown in fig. 5 and fig. 6, the difference from embodiment 1 is that the deep hole plate 1 includes multiple rows of sub-plates 5, in this embodiment, the deep hole plate 1 includes six rows of sub-plates 5, and the arrangement of the multiple rows of sub-plates 5 can be adjusted according to the number of samples, thereby reducing the waste of resources.

The cover plate 2 comprises a plurality of rows of sub cover plates 6, the deep-hole plate 1 comprises six rows of sub cover plates 6 in the embodiment, and the sub cover plates 6 correspond to the sub plates 5 one by one; the magnetic sleeve head 21 is arranged on the lower surface of the sub-cover plate 6, and when the sub-cover plate 6 is covered on the sub-plate 5, the magnetic sleeve head 21 is inserted in the deep hole 13; two limiting plates 22 are respectively fixedly arranged at two ends of the lower surface of the cover plate 2, when the sub-cover plate 6 is arranged on the daughter board 5, the two limiting plates 22 are abutted against two sides of the daughter board 5, and therefore the sub-cover plate 6 can be covered on the daughter board 5.

Deep hole board 1 can be dismantled and connect on annular frame 4, and two fixed slots 41 have been seted up to the upper surface of annular frame 4, and two fixed slots 41 are located the both ends of annular frame 4 respectively, and fixed slot 41 sets up along the length direction of annular frame 4, and fixed slot 41 is located the upper end of annular frame 4 inner peripheral surface. The outer peripheral face integrated into one piece of daughter board 5 has two stoppers 12, and two stoppers 12 are located the both sides of daughter board 5 respectively, and when placing deep hole board 1 in annular frame 4, two stoppers 12 butt respectively in the upper surface of two fixed slots 41, through stopper 12 and fixed slot 41, realize the support to daughter board 5. The lower surface of stopper 12 sets firmly inserts piece 121, and inserting groove 42 has been seted up in the lower surface of fixed slot 41 to annular frame 4, and when placing stopper 12 in fixed slot 41, inserting piece 121 pegs graft in inserting groove 42, can further increase the fixed ability to deep-hole board 1.

The specific working principle in this application: in the process of extracting nucleic acid, the deep hole plate 1 is placed on the heating module 3, the pipe body of the deep hole plate 1 is inserted into the heating hole 321, meanwhile, the convex column 33 is inserted into the abdicating groove 11, and the convex column 33 can heat the peripheral surface of the pipe body of the deep hole plate 1; in addition, the number of the sub-plates 5 can be selected according to the number of samples by arranging the sub-plates 5, thereby reducing the waste of resources.

The embodiments of the present invention are preferred embodiments of the present application, and the scope of protection of the present application is not limited by the embodiments, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.

Claims (9)

1. The utility model provides a 24 hole consumptive materials for nucleic acid extraction appearance, include deep hole board (1) and install in apron (2) on deep hole board (1), be provided with magnetic sleeve head (21) on apron (2), its characterized in that, 24 deep holes (13) have been seted up on deep hole board (1), set up groove of stepping down (11) on deep hole board (1), groove of stepping down (11) with deep hole (13) are seted up in the both sides of deep hole board (1).

2. The consumable 24-well for nucleic acid isolation instrument according to claim 1, wherein the height of the concession groove (11) is 2.5-6 cm.

3. The consumable of 24-hole nucleic acid extractor according to claim 2, wherein the recess (11) is provided in plurality, and four recess grooves (11) are surrounded at the bottom of the deep hole (13).

4. The 24-well consumable for the nucleic acid extractor according to claim 3, wherein the outer peripheral surface of the deep-well plate (1) is provided with an annular frame (4), the deep hole (13) and the abdicating groove (11) are positioned in the ring of the annular frame (4), the upper surface of the annular frame (4) is positioned in the middle of the outer peripheral surface of the deep-well plate (1), and the lower surface of the annular frame (4) is lower than the lower surface of the deep-well plate (1).

5. The consumable 24-well plate for nucleic acid extractor according to claim 4, wherein the annular frame (4) is fixedly connected to the deep-well plate (1).

6. The consumable 24-well plate for nucleic acid extractor according to claim 4, wherein the deep-well plate (1) and the annular frame (4) are detachably connected.

7. The consumable 24 holes for nucleic acid extracting instrument according to claim 6, wherein the upper surface of the annular frame (4) is provided with two fixing grooves (41) which are oppositely arranged, the outer peripheral surface of the deep hole plate (1) is provided with two limiting blocks (12) which are oppositely arranged, when the deep hole plate (1) is inserted into the annular frame (4), the limiting blocks (12) are installed in the fixing grooves (41), and the limiting blocks (12) and the fixing grooves (41) are in one-to-one correspondence.

8. The consumable with 24 holes for the nucleic acid extractor according to claim 7, wherein an insertion block (121) is disposed on one side of the limit block (12) away from the opening of the deep hole (13), the insertion block (121) is disposed on one end of the limit block (12) away from the deep hole plate (1), an insertion groove (42) is disposed on the bottom wall of the fixing groove (41) of the annular frame (4), and when the deep hole plate (1) is inserted into the annular frame (4), the insertion block (121) is mounted in the insertion groove (42).

9. The consumable 24-well plate for a nucleic acid extractor according to claim 8, wherein the deep-well plate (1) comprises a plurality of rows of sub-plates (5), and the two stoppers (12) are respectively located on two sides of the sub-plates (5).

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