CN214458051U - Magnetic rack - Google Patents
Magnetic rack Download PDFInfo
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- CN214458051U CN214458051U CN202022557686.8U CN202022557686U CN214458051U CN 214458051 U CN214458051 U CN 214458051U CN 202022557686 U CN202022557686 U CN 202022557686U CN 214458051 U CN214458051 U CN 214458051U
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Abstract
The embodiment of the utility model provides a magnetic rack, which comprises a rack body and at least two iron blocks arranged on the rack body side by side; defining that the axial direction of the iron block is a first direction, and the direction vertical to the first direction in the horizontal plane is a second direction; the magnetic frame comprises a first magnet and a second magnet which are positioned between adjacent iron blocks and arranged side by side along a first direction, and the axial directions of the first magnet and the second magnet are arranged along a second direction; the magnetic force frame also comprises a gear piece which is arranged corresponding to the first magnet, the axial direction of the gear piece is arranged along the first direction, and the gear piece comprises a gear part and an accommodating groove which is used for accommodating and fixing the second magnet; the gear piece is configured to bring the second magnet into rotation about an axis of the gear piece so that the second magnet rotates relative to the first magnet. The centrifugal tube does not need to be taken down during magnetic bead purification, the operation is simple, and the experimental time is saved.
Description
Technical Field
The utility model relates to a nucleic acid purification technical field, more specifically relates to a magnetic force frame.
Background
The magnetic bead method for extracting nucleic acid is to crack a sample by using a cracking solution, nucleic acid molecules after the sample is cracked are specifically adsorbed on the surfaces of magnetic particles through reaction, and impurities such as protein and the like cannot be adsorbed and remained in liquid. After a period of reaction, under the action of magnetic field, separating magnetic particles from liquid, recovering particles (i.e. magnetic beads and nucleic acid molecule conjugates), washing with washing liquid to remove impurities nonspecifically adsorbed on the magnetic beads, and eluting to obtain pure nucleic acid.
The magnetic force frame among the prior art generally adopts the adsorption mode of fixed magnet, has a great deal of inconvenience on subsequent processing, for example the operation that need take off the centrifuging tube when the magnetic bead purification, and the process is comparatively loaded down with trivial details complicacy and waste experimental time.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a magnetic frame to the realization need not to take off the centrifuging tube when the magnetic bead purification, easy operation practices thrift the experimental time.
To achieve the above object, the present invention provides a magnetic rack, which comprises
The iron block rack comprises a rack body and at least two iron blocks arranged on the rack body side by side;
defining that the axial direction of the iron block is a first direction, and the direction vertical to the first direction in the horizontal plane is a second direction;
the magnetic frame comprises a first magnet and a second magnet which are positioned between adjacent iron blocks and arranged side by side along a first direction, and the axial directions of the first magnet and the second magnet are arranged along a second direction;
the magnetic force frame further comprises a gear piece arranged corresponding to the first magnet, the axial direction of the gear piece is arranged along the first direction, and the gear piece comprises a gear part and an accommodating groove used for accommodating and fixing the second magnet;
the gear piece is configured to bring the second magnet into rotation about an axis of the gear piece so that the second magnet rotates relative to the first magnet.
In addition, preferably, the magnetic frame further comprises a pull rod, and the pull rod is provided with rack teeth matched with the gear part of the gear piece.
In addition, it is preferable that the polarities of the same sides of the first and second magnets are the same so that the iron blocks on both sides of the first magnet have magnetism.
In addition, it is preferable that the polarities of the same sides of the first and second magnets are different so that the iron blocks on both sides of the first magnet have no magnetism.
In addition, preferably, the frame body of the magnetic frame comprises a first plate body, a second plate body and a third plate body;
the first plate body, the second plate body and the third plate body are combined and fixed;
the first plate body comprises a first groove body for accommodating the first magnet and second groove bodies for accommodating the iron blocks respectively;
the gear piece is accommodated and fixed between the second plate body and the third plate body.
In addition, preferably, the first plate body is recessed inwards to form a limiting groove close to the side wall surface of the second plate body; the surface of the side wall of the second plate body, which is close to the first plate body, protrudes outwards to form a first limiting part which is arranged corresponding to the limiting groove;
the first plate body and the second plate body are assembled and fixed with the first limiting part through the limiting groove.
In addition, the preferred scheme is that the third plate body including with the second plate body corresponds the bellying that sets up, the bellying is close to the outside arch of lateral wall surface of first plate body is formed with the spacing portion of second that the spacing groove corresponds the setting, first plate body and third plate body pass through spacing groove and the spacing portion assembly of second and fix.
In addition, preferably, the cross section of the limiting groove is a trapezoidal table, and the cross sections of the first limiting part and the second limiting part are inverted trapezoidal tables matched with the limiting groove.
In addition, the preferred scheme is that the surface that first plate body is kept away from the second plate body is outwards protruding to form the extension, the extension is including a plurality of through-hole that is used for holding the centrifuging tube.
In addition, preferably, the magnetic rack further comprises a pull rod, the second plate body comprises a pull rod groove for accommodating the pull rod, and the pull rod is provided with rack teeth matched with the gear part of the gear part; the pull rod is configured to rotate the gear piece.
The beneficial effect of this application does:
the utility model provides a magnetic force frame adopts the cooperation between first magnet, second magnet and the iron plate, drives the relative first magnet rotation of second magnet through gear spare to the magnetic has or not on the control iron plate, has realized need not to take off the centrifuging tube when the magnetic bead purification, easy operation practices thrift the experimental time.
Drawings
Fig. 1 is an overall schematic view of a magnetic rack in an embodiment of the present invention.
Fig. 2 is a top sectional view of the magnetic stand according to an embodiment of the present invention.
Detailed Description
Various exemplary embodiments of the present invention will now be described in detail with reference to the accompanying drawings. It should be noted that: unless specifically stated otherwise, the relative arrangement of the components and steps, the numerical expressions, and numerical values set forth in these embodiments do not limit the scope of the present invention.
The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the invention, its application, or uses.
Techniques and apparatus known to those of ordinary skill in the relevant art may not be discussed in detail, but are intended to be considered a part of the specification where appropriate.
In all examples shown and discussed herein, any particular value should be construed as merely illustrative, and not limiting. Thus, other examples of the exemplary embodiments may have different values.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, further discussion thereof is not required in subsequent figures.
Need not to take off the centrifuging tube in order to realize when the magnetic bead purification, easy operation practices thrift the experimental time. In an embodiment of the present invention, there is provided a magnetic rack, as shown in fig. 1-2, specifically, the magnetic rack includes a rack body and at least two iron blocks arranged side by side on the rack body; in one particular example, a first iron block 7, a second iron block 8 and a third iron block 9 are included in the magnetic stand.
Defining that the axial direction of the iron block is a first direction, and the direction vertical to the first direction in the horizontal plane is a second direction; in the example shown in fig. 1, the first direction is a direction of the axes of the first iron block 7, the second iron block 8, and the third iron block 9, i.e., a direction extending from the upper right to the lower left; the second direction is a direction extending from top left to bottom right.
The magnetic frame comprises a first magnet and a second magnet which are positioned between the adjacent iron blocks and arranged side by side along a first direction, and the axial directions of the first magnet and the second magnet are arranged along a second direction; in one particular example, the magnet holder comprises a first magnet 11 and a second magnet 10 located between the first iron 7 and the second iron 8, and a third magnet 12 and a fourth magnet 13 located between the second iron 8 and the third iron 9.
The magnetic force frame further comprises a gear piece which is arranged corresponding to the first magnet 11, the axial direction of the gear piece is arranged along the first direction, and the gear piece comprises a gear part and an accommodating groove 16 for accommodating and fixing the second magnet 10; the gear member is configured to bring the second magnet 10 into rotation about its axis such that the second magnet 10 rotates relative to the first magnet 11. For example, the second magnet may be rotated 180 ° relative to the first magnet. In a specific example, the magnetic rack includes a first gear member 21 disposed corresponding to the first magnet 11 and a second gear member 14 disposed corresponding to the third magnet 12, respectively, the first gear member 21 receives and fixes the second magnet 10 therein, and the second gear member 14 receives and fixes the fourth magnet 13 therein.
The utility model provides a magnetic force frame adopts the cooperation between first magnet, second magnet and the iron plate, drives the relative first magnet rotation of second magnet through gear spare to the magnetic has or not on the control iron plate, has realized need not to take off the centrifuging tube when the magnetic bead purification, easy operation practices thrift the experimental time. And the magnetic force frame can realize the generation and disappearance of the magnetic force without consuming any electric energy, does not contain any electronic component, and has simple structure and high reliability.
In a specific embodiment, referring to fig. 1, the magnetic rack further comprises a pull rod 15, and the pull rod 15 is provided with rack teeth matched with the gear part of the gear part. The gear portion cooperation through the rack and gear piece of pull rod 15 and then drive gear piece and rotate, and then drive second magnet 10 and rotate, make the conversion take place in the position of the two poles of the earth of holding tank 16 internal fixation second magnet 10, further realize magnetic force on the magnet have or not, easy operation pulling pull rod 15 can need not other operations, uses manpower sparingly simultaneously.
In one embodiment, the same side of the first magnet 11 and the second magnet 10 has the same polarity, so that the iron blocks on both sides of the first magnet 11 have magnetism. For example, the left polarity of the first magnet 11 and the left polarity of the second magnet 10 are both S-poles, and the iron blocks on both sides of the first magnet 11 have magnetism. When the second magnet 10 rotates 180 ° relative to the first magnet 11, that is, the left end of the second magnet 10 rotates 180 ° so that the left end of the second magnet 10 corresponds to the right end of the first magnet 11, and at this time, the S pole of the first magnet 11 and the N pole of the second magnet 10 are on the same side, the first magnet 11 and the second magnet 10 form a closed magnetic path, and the polarities of the same side of the first magnet 11 and the second magnet 10 are different so that the iron blocks on both sides of the first magnet 11 do not have magnetism. Through the change that is the magnet magnetic pole of arranging side by side on the first direction, realize the switching in magnetic path, reach the magnetism on the iron plate and produce and the quick switching that disappears, reduced the operating procedure that need take off the centrifuging tube when the magnetic bead purification, reduced the required time of experiment, accord with the requirement of nucleic acid purification experiment.
In one embodiment, as shown in fig. 1, the frame body of the magnetic frame includes a first plate body 1, a second plate body 2 and a third plate body 3; the first plate body 1, the second plate body 2 and the third plate body 3 are combined and fixed; the first plate body 1 comprises a first groove body 5 for accommodating the first magnet 11 and second groove bodies 6 for accommodating the iron blocks respectively;
the gear piece is accommodated and fixed between the second plate body 2 and the third plate body 3. Through the installation cooperation between first plate body 1 and second plate body 2 and the third plate body 3 for the simple structure of magnetic frame dismantles simple to operate, can hold the gear spare simultaneously through the cooperation of second plate body 2 and third plate body 3 and fix between second plate body 2 and third plate body 3.
Preferably, the side wall surface of the first plate body 1 close to the second plate body 2 is recessed inwards to form a limiting groove 17; a first limiting part 18 corresponding to the limiting groove 17 is formed on the surface, close to the side wall of the first plate body 1, of the second plate body 2 in an outward protruding manner; the first plate body 1 and the second plate body 2 are assembled and fixed through the limiting groove 17 and the first limiting portion 18. Through the cooperation between the spacing groove 17 on the first plate body 1 and the first spacing portion 18 on the second plate body 2, make the dismantlement simple to operate and the stable in structure safety of magnetic frame.
In a specific embodiment, the third plate body 3 includes a protruding portion corresponding to the second plate body 2, a groove corresponding to the gear is provided on the protruding portion, a second limiting portion 19 corresponding to the limiting groove 17 is formed on the protruding portion, which is close to the side wall surface of the first plate body 1, and the first plate body 1 and the third plate body 3 are assembled and fixed through the limiting groove 17 and the second limiting portion 19. Through the installation cooperation of the limiting groove 17 on the first plate body 1 and the second limiting part 19 on the third plate body 3, the magnetic frame is convenient and quick to detach and install and is stable and safe in structure.
In a specific embodiment, the cross section of the limiting groove 17 is a trapezoid table, and the cross sections of the first limiting portion 18 and the second limiting portion 19 are inverted trapezoid tables matched with the limiting groove 17.
In one embodiment, as shown in fig. 1, the surface of the first plate 1 away from the second plate 2 protrudes outward to form an extension, and the extension includes a plurality of through holes 4 for accommodating centrifuge tubes. The centrifuging tube of guaranteeing to place at through-hole 4 corresponds with the iron plate, and an end butt centrifuging tube's of iron plate outside diapire for adsorb the magnetic particle in the centrifuging tube.
In order to fix the pull rod 15, in a specific embodiment, referring to fig. 1, the magnetic rack further includes a pull rod 15, the second plate 2 includes a pull rod groove 20 for receiving the pull rod 15, and the pull rod 15 is provided with rack teeth matched with the gear portion of the gear member; the pull rod 15 is configured to rotate the gear member. The gear rack has the advantages that the pull rod 15 can be fixed, the slotting direction of the pull rod groove 20 is the second direction, when the pull rod 15 is pulled, the pull rod 15 is fixed in the pull rod groove 20 and can move in the pull rod groove 20 along the second direction, meanwhile, the movement of the pull rod 15 in the first direction is limited, the fixing and guiding effects are achieved, the pull rod 15 is prevented from being separated from the gear part of the gear part, and the section of the plane of the pull rod groove 20 perpendicular to the first direction and the second direction is in an inverted U shape.
In actual use, as shown in fig. 1-2, at this time, the same side polarity of the first magnet 11 and the second magnet 10 is the S-pole, a closed magnetic path is not formed between the first magnet 11 and the second magnet 10, the same side polarity of the third magnet 12 and the fourth magnet 13 is the S-pole, and a closed magnetic path is not formed between the third magnet 12 and the fourth magnet 13, so that the first iron block 7, the second iron block 8, and the third iron block 9 are magnetized to adsorb magnetic beads in the centrifuge tube. Then the pull rod 15 is pulled, the pull rod 15 drives the gear piece to rotate through the rack-and-pinion matching gear part, the first gear piece 21 and the second gear piece 14 drive the second magnet 10 fixed in the first gear piece 21 accommodating groove 16 and the fourth magnet 13 fixed in the second gear piece 14 accommodating groove 16 to rotate 180 degrees around the gear piece axial direction, namely the first direction, at the moment, the same sides of the first magnet 11 and the second magnet 10 have different magnetic poles, the same side of the S pole of the first magnet 11 corresponds to the N pole of the second magnet 10, a closed magnetic path is formed between the first magnet 11 and the second magnet 10, the same sides of the third magnet 12 and the fourth magnet 13 have different magnetic poles, the same side of the S pole of the third magnet 12 corresponds to the N pole of the fourth magnet 13, the third magnet 12 and the fourth magnet 13 form a closed magnetic path, so that the magnetic particles in the centrifuge tube can not be adsorbed when the magnetism on the first iron block 7, the second iron block 8 and the third iron block 9 disappears. Promote pull rod 15 and reset pull rod 15, at this moment, first magnet 11 and second magnet 10 homonymy polarity are the S utmost point all the same, do not form closed magnetic path between first magnet 11 and the second magnet 10, third magnet 12 and fourth magnet 13 homonymy polarity all are the S utmost point, do not form closed magnetic path between third magnet 12 and the fourth magnet 13, then first magnet 11, second magnet 10, third magnet 12 and fourth magnet 13 make first iron plate 9 again, thereby second iron plate 8 and third iron plate 7 take magnetism to adsorb the magnetic bead in the centrifuging tube, thereby magnetism produces and the effect that disappears on the realization iron plate.
Obviously, the above embodiments of the present invention are only examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention, and it is obvious for those skilled in the art to make other variations or changes based on the above descriptions, and all the embodiments cannot be exhausted here, and all the obvious variations or changes that belong to the technical solutions of the present invention are still in the protection scope of the present invention.
Claims (10)
1. A magnetic stand, comprising:
the iron block rack comprises a rack body and at least two iron blocks arranged on the rack body side by side;
defining that the axial direction of the iron block is a first direction, and the direction vertical to the first direction in the horizontal plane is a second direction;
the magnetic frame comprises a first magnet and a second magnet which are positioned between adjacent iron blocks and arranged side by side along a first direction, and the axial directions of the first magnet and the second magnet are arranged along a second direction;
the magnetic force frame further comprises a gear piece arranged corresponding to the first magnet, the axial direction of the gear piece is arranged along the first direction, and the gear piece comprises a gear part and an accommodating groove used for accommodating and fixing the second magnet;
the gear piece is configured to bring the second magnet into rotation about an axis of the gear piece so that the second magnet rotates relative to the first magnet.
2. The magnetic rack according to claim 1, further comprising a pull rod, wherein the pull rod is provided with rack teeth engaged with the gear portion of the gear member.
3. A magnetic frame as claimed in claim 1, wherein the same side of the first and second magnets has the same polarity so that the iron blocks on either side of the first magnet are magnetic.
4. A magnetic frame as claimed in claim 1, wherein the polarity of the same side of the first and second magnets is different so that the iron blocks on either side of the first magnet are non-magnetic.
5. The magnetic rack according to claim 1, wherein the rack body of the magnetic rack comprises a first plate body, a second plate body and a third plate body;
the first plate body, the second plate body and the third plate body are combined and fixed;
the first plate body comprises a first groove body for accommodating the first magnet and second groove bodies for accommodating the iron blocks respectively;
the gear piece is accommodated and fixed between the second plate body and the third plate body.
6. The magnetic rack of claim 5, wherein the first plate body is recessed inwardly adjacent to the side wall surface of the second plate body to form a retaining groove; the surface of the side wall of the second plate body, which is close to the first plate body, protrudes outwards to form a first limiting part which is arranged corresponding to the limiting groove;
the first plate body and the second plate body are assembled and fixed with the first limiting part through the limiting groove.
7. The magnetic rack according to claim 6, wherein the third plate comprises a protruding portion corresponding to the second plate, the protruding portion protrudes outward from a surface of the side wall of the first plate, and a second limiting portion corresponding to the limiting groove is formed, and the first plate and the third plate are assembled and fixed through the limiting groove and the second limiting portion.
8. The magnetic rack of claim 7, wherein the cross section of the limiting groove is a trapezoidal platform, and the cross sections of the first limiting part and the second limiting part are inverted trapezoidal platforms matched with the limiting groove.
9. The magnetic rack of claim 5, wherein the surface of the first plate body away from the second plate body protrudes outward to form an extension portion, and the extension portion includes a plurality of through holes for receiving centrifuge tubes.
10. The magnetic rack according to claim 5, wherein the magnetic rack further comprises a pull rod, the second plate body comprises a pull rod groove for accommodating the pull rod, and the pull rod is provided with rack teeth matched with the gear part of the gear part; the pull rod is configured to rotate the gear piece.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022557686.8U CN214458051U (en) | 2020-11-06 | 2020-11-06 | Magnetic rack |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022557686.8U CN214458051U (en) | 2020-11-06 | 2020-11-06 | Magnetic rack |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214458051U true CN214458051U (en) | 2021-10-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022557686.8U Active CN214458051U (en) | 2020-11-06 | 2020-11-06 | Magnetic rack |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214458051U (en) |
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2020
- 2020-11-06 CN CN202022557686.8U patent/CN214458051U/en active Active
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| CP01 | Change in the name or title of a patent holder |
Address after: 100192 building 4, Tiandi Linfeng, No.1, yongtaizhuang North Road, Haidian District, Beijing Patentee after: Beijing quanshijin Biotechnology Co.,Ltd. Address before: 100192 building 4, Tiandi Linfeng, No.1, yongtaizhuang North Road, Haidian District, Beijing Patentee before: BEIJING TRANSGEN BIOTECH Co.,Ltd. |
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| CP01 | Change in the name or title of a patent holder |